Crocetti, Letizia; Giovannoni, Maria Paola; Guerrini, Gabriella; Lamanna, Silvia; Melani, Fabrizio; Bartolucci, Gian Luca; Pallecchi, Marco; Paoli, Paola; Lippi, Martina; Wang, Junjie; Dahl, Gerhard (2023). Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 24, pp. 1-23, ISSN:1422-0067 DOI   Accesso ONLINE all'editore

  Tomarchio, Rosario; Patamia, Vincenzo; Zagni, Chiara; Crocetti, Letizia; Cilibrizzi, Agostino; Floresta, Giuseppe; Rescifina, Antonio (2023). Steered Molecular Dynamics Simulations Study on FABP4 Inhibitors. MOLECULES, vol. 28, pp. 2731-2749, ISSN:1420-3049 DOI  

  Crocetti, Letizia; Guerrini, Gabriella; Melani, Fabrizio; Vergelli, Claudia; Giovannoni, Maria Paola (2023). 4,5-Dihydro-5-Oxo-Pyrazolo[1,5-a]Thieno[2,3-c]Pyrimidine: A Novel Scaffold Containing Thiophene Ring. Chemical Reactivity and In Silico Studies to Predict the Profile to GABAA Receptor Subtype. MOLECULES, vol. 28, pp. 3054-3074, ISSN:1420-3049 DOI  

  Gerace A.; Masini V.; Crocetti L.; Giovannoni M.P.; Ferraroni M. (2023). X-ray structural study of human neutrophil elastase inhibition with a series of azaindoles, azaindazoles and isoxazolones. JOURNAL OF MOLECULAR STRUCTURE, vol. 1274, pp. 134595-134601, ISSN:0022-2860 DOI  

  Crocetti, Letizia; Floresta, Giuseppe; Cilibrizzi, Agostino; Giovannoni, Maria Paola (2022). An Overview of PDE4 Inhibitors in Clinical Trials: 2010 to Early 2022. MOLECULES, vol. 27, pp. 4964-4989, ISSN:1420-3049 DOI  

  Claudia Vergelli, Letizia Crocetti, Maria Paola Giovannoni, Giuseppe Floresta, Shabnam Nazir, Amrit Bhogal, Claudio Biancalani, Nicoletta Cesari, Agostino Cilibrizzi (2022). Synthesis and inverse virtual screening of new bi-cyclic structures towards cancer-relevant cellular targets. STRUCTURAL CHEMISTRY, pp. 0-0, ISSN:1040-0400 DOI  

  Crocetti, Letizia; Guerrini, Gabriella; Giovannoni, Maria Paola; Melani, Fabrizio; Lamanna, Silvia; Di Cesare Mannelli, Lorenzo; Lucarini, Elena; Ghelardini, Carla; Wang, Junjie; Dahl, Gerhard (2022). New Panx-1 Blockers: Synthesis, Biological Evaluation and Molecular Dynamic Studies. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23, pp. 4827-4855, ISSN:1422-0067 DOI  

  Cantini N.; Schepetkin I.A.; Danilenko N.V.; Khlebnikov A.I.; Crocetti L.; Giovannoni M.P.; Kirpotina L.N.; Quinn M.T. (2022). Pyridazinones and Structurally Related Derivatives with Anti-Inflammatory Activity. MOLECULES, vol. 27, pp. 3749-3776, ISSN:1420-3049 DOI  

  Floresta, Giuseppe; Crocetti, Letizia; Zagni, Chiara; Cilibrizzi, Agostino (2022). Pyridazin-3(2H)-one as New FABP4 Inhibitors Suggested by Molecular Growing Experiments. MEDICAL SCIENCES FORUM, pp. 19-19, ISSN:2673-9992 DOI  

  Crocetti, Letizia; Floresta, Giuseppe; Zagni, Chiara; Merugu, Divya; Mazzacuva, Francesca; de Oliveira Silva, Renan Rodrigues; Vergelli, Claudia; Giovannoni, Maria Paola; Cilibrizzi, Agostino (2022). Ligand Growing Experiments Suggested 4-amino and 4-ureido pyridazin-3(2H)-one as Novel Scaffold for FABP4 Inhibition. PHARMACEUTICALS, vol. 15, pp. 1335-1365, ISSN:1424-8247 DOI  

  Crocetti, Letizia; Quinn, Mark T; Cilibrizzi, Agostino; Giovannoni, Maria Paola (2022). Editorial: Serine protease inhibitors and their therapeutic applications. FRONTIERS IN CHEMISTRY, vol. 10, pp. 980152-980155, ISSN:2296-2646 DOI  

  Letizia Crocetti, Gabriella Guerrini, Claudia Vergelli, Maria Paola Giovannoni, Gian Luca Bartolucci, Silvia Lamanna, Marco Pallecchi, Paola Paoli, Patrizia Rossi (2022). Molecular manipulation of the 1,5,6,7-tetrahydro-4 H -indazol-4-one scaffold to obtain new human neutrophil elastase (HNE) inhibitors. JOURNAL OF MOLECULAR STRUCTURE, vol. 1263, pp. 133140-133154, ISSN:0022-2860 DOI   Accesso ONLINE all'editore

  Letizia Crocetti, Gabriella Guerrini, Fabrizio Melani, Claudia Vergelli, Maria Paola Giovannoni, Maria Paola Mascia (2022). GABAA receptor modulators with a pyrazolo[1,5-a]quinazoline core: synthesis, molecular modelling studies and electrophysiological assay. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23, pp. 13032-13051, ISSN:1422-0067 DOI  

  Crocetti, Letizia; Vergelli, Claudia; Guerrini, Gabriella; Giovannoni, Maria Paola; Kirpotina, Liliya N.; Khlebnikov, Andrei I.; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Lucarini, Elena; Schepetkin, Igor A.; Quinn, Mark T. (2021). Pyridinone Derivatives as Interesting Formyl Peptide Receptor (FPR) Agonists for the Treatment of Rheumatoid Arthritis. MOLECULES, vol. 26, pp. 6583-6583, ISSN:1420-3049 DOI   Accesso ONLINE all'editore

  Cantini, Niccolò; Khlebnikov, Andrei I.; Crocetti, Letizia; Schepetkin, Igor A.; Floresta, Giuseppe; Guerrini, Gabriella; Vergelli, Claudia; Bartolucci, Gianluca; Quinn, Mark T.; Paola Giovannoni, Maria (2021). Exploration of Nitrogen Heterocycle Scaffolds for the Development of Potent Human Neutrophil Elastase Inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 29, pp. 1-17, ISSN:0968-0896 DOI  

  Crocetti, Letizia; Guerrini, Gabriella; Puglioli, Sara; Giovannoni, Maria Paola; Di Cesare Mannelli, Lorenzo; Lucarini, Elena; Ghelardini, Carla; Wang, Junjie; Dahl, Gerhard (2021). Design and synthesis of the first indole-based blockers of Panx-1 channel. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 223, pp. 113650-113660, ISSN:0223-5234 DOI  

  Cantini, Niccolo; Crocetti, Letizia; Guerrini, Gabriella; Vergelli, Claudia; Schepetkin, Igor A; Pallecchi, Marco; Bartolucci, Gian Luca; Quinn, Mark T; Teodori, Elisabetta; Paola Giovannoni, Maria (2021). 1,5,6,7-Tetrahydro-4H-indazol-4-ones as human neutrophil elastase (HNE) inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 52, pp. 128380-128386, ISSN:0960-894X DOI  

  Vergelli C.; Khlebnikov A.I.; Crocetti L.; Guerrini G.; Cantini N.; Kirpotina L.N.; Schepetkin I.A.; Cilibrizzi A.; Quinn M.T.; Rossi P.; Paoli P.; Giovannoni M.P. (2021). Synthesis, biological evaluation, molecular modeling, and structural analysis of new pyrazole and pyrazolone derivatives as N-formyl peptide receptors agonists. CHEMICAL BIOLOGY & DRUG DESIGN, vol. 98, pp. 582-603, ISSN:1747-0277 DOI  

  Crocetti, Letizia; Guerrini, Gabriella; Cantini, Niccolò; Vergelli, Claudia; Melani, Fabrizio; Mascia, Maria Paola; Giovannoni, Maria Paola (2021). 'Proximity frequencies' a new parameter to evaluate the profile of GABAAR modulators. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 34, pp. 127755-127762, ISSN:0960-894X DOI  

  Crocetti L.; Giovannoni M.P.; Cantini N.; Guerrini G.; Vergelli C.; Schepetkin I.A.; Khlebnikov A.I.; Quinn M.T. (2020). Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors. FRONTIERS IN CHEMISTRY, vol. 8, pp. 795-811, ISSN:2296-2646 DOI  

  Crocetti, Letizia; Guerrini, Gabriella (2020). GABAA receptor subtype modulators in medicinal chemistry: an updated patent review (2014-present). EXPERT OPINION ON THERAPEUTIC PATENTS, vol. .., pp. 1-24, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  Crocetti L.; Vergelli C.; Guerrini G.; Cantini N.; Kirpotina L.N.; Schepetkin I.A.; Quinn M.T.; Parisio C.; Di Cesare Mannelli L.; Ghelardini C.; Giovannoni M.P. (2020). Novel formyl peptide receptor (FPR) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis. BIOORGANIC CHEMISTRY, vol. 100, pp. 1-12, ISSN:0045-2068 DOI  

  Floresta G.; Crocetti L.; Giovannoni M.P.; Biagini P.; Cilibrizzi A. (2020). Repurposing strategies on pyridazinone-based series by pharmacophore- and structure-driven screening. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 1137-1144, ISSN:1475-6366 DOI  

  Μaione, Francesco; Colucci, Mariantonella; Raucci, Federica; Mangano, Giorgina; Marzoli, Francesca; Mascolo, Nicola; Crocetti, Letizia; Giovannoni, Maria Paola; Di Giannuario, Amalia; Pieretti, Stefano (2020). New insights on the arylpiperazinylalkyl pyridazinone ET1 as potent antinociceptive and anti-inflammatory agent. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 888, pp. 173572-173585, ISSN:0014-2999 DOI  

  Maria Paola Giovannoni, Letizia Crocetti, Niccolò Cantini, Gabriella Guerrini, Claudia Vergelli, Antonella Iacovone, Elisabetta Teodori, Igor A. Schepetkin, Mark T. Quinn, Samuele Ciattini,Patrizia Rossi, Paola Paoli (2020). New 3-unsubstituted Isoxazolones as Potent Human Neutrophil Elastase Inhibitors: Synthesis and Molecular Dynamic Simulation. DRUG DEVELOPMENT RESEARCH, vol. 81, pp. 338-349, ISSN:1098-2299 DOI   Accesso ONLINE all'editore

  Giovannoni M.P.; Cantini N.; Crocetti L.; Guerrini G.; Iacovone A.; Schepetkin I.A.; Vergelli C.; Khlebnikov A.I.; Quinn M.T. (2019). Further modifications of 1H-pyrrolo[2,3-b]pyridine derivatives as inhibitors of human neutrophil elastase. DRUG DEVELOPMENT RESEARCH, vol. 2019, pp. 1-12, ISSN:0272-4391 DOI   Accesso ONLINE all'editore

  Guerrini, Gabriella; Vergelli, Claudia; Cantini, Niccolò; Giovannoni, Maria; Daniele, Simona; Mascia, Maria Paola; Martini, Claudia; Crocetti, Letizia (2019). Synthesis of New GABAA Receptor Modulator with Pyrazolo[1,5-a]quinazoline (PQ) Scaffold. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, pp. 1438-1457, ISSN:1422-0067 DOI  

  Gabriella Guerrini, Letizia Crocetti, Simona Daniele, Antonella Iacovone, Niccolò Cantini,Claudia Martini, Fabrizio Melani, Claudia Vergelli, Maria Paola Giovannoni, (2019). New 3,6-disubstituted pyrazolo[1,5-a]quinazolines as ligands to GABAA receptor subtype. JOURNAL OF HETEROCYCLIC CHEMISTRY, vol. 56, pp. 1571-1580, ISSN:1943-5193 DOI  

  Crocetti L.; Quinn M.T.; Schepetkin I.A.; Giovannoni M.P. (2019). A patenting perspective on human neutrophil elastase (HNE) inhibitors (2014-2018) and their therapeutic applications. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 29, pp. 555-578, ISSN:1354-3776 DOI  

  Letizia Crocetti, Maria Paola Giovannoni, Igor A. Schepetkinb, Mark T. Quinn, Andrei I. Khlebnikovc, Niccolò Cantini, Gabriella Guerrini, Antonella Iacovone, Elisabetta Teodori, Claudia Vergelli (2018). 1H-pyrrolo[2,3-b]pyridine: a new scaffold for human neutrophil elastase (HNE) inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 26, pp. 5583-5595, ISSN:0968-0896 DOI  

  Giovannoni, Maria Paola; Schepetkin, Igor A.; Quinn, Mark T.; Cantini, Niccolò; Crocetti, Letizia*; Guerrini, Gabriella; Iacovone, Antonella; Paoli, Paola; Rossi, Patrizia; Bartolucci, Gian Luca; Menicatti, Marta; Vergelli, Claudia (2018). Synthesis, biological evaluation, and molecular modelling studies of potent human neutrophil elastase (HNE) inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 1108-1124, ISSN:1475-6366 DOI  

  Guerrini, Gabriella; Ciciani, Giovanna; Crocetti, Letizia; Daniele, Simona; Ghelardini, Carla; Giovannoni, MARIA PAOLA; Iacovone, Antonella; DI CESARE MANNELLI, Lorenzo; Martini, Claudia; Vergelli, Claudia (2017). Identification of a new pyrazolo[1,5-a]quinazoline ligand highly affine to γ-aminobutyric type A (GABAA) receptor subtype with anxiolytic-like and antihyperalgesic activity. JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, pp. 9691-9702, ISSN:0022-2623 DOI  

  Crocetti, Letizia; Bartolucci Gian Luca, ; Cilibrizzi, Agostino; Giovannoni, Maria Paola; Guerrini, Gabriella; Iacovone, Antonella; Menicatti, Marta; Schepetkin, Igor A; Khlebnikov, Andrei I; Quinn, Mark T; Vergelli, Claudia (2017). Synthesis and analytical characterization of new thiazol-2-(3H)-ones as human neutrophil elastase (HNE) inhibitors. CHEMISTRY CENTRAL JOURNAL, vol. 11, pp. 127-141, ISSN:1752-153X DOI  

  Di Cesare Mannelli, Lorenzo; Micheli, Laura; Crocetti, Letizia; Giovannoni, Maria Paola; Vergelli, Claudia; Ghelardini, Carla (2017). α2 Adrenoceptor: a Target for Neuropathic Pain Treatment. MINI-REVIEWS IN MEDICINAL CHEMISTRY, vol. 16, pp. 95-107, ISSN:1875-5607 DOI  

  Vergelli, Claudia; Schepetkin, Igor A.; Ciciani, Giovanna; Cilibrizzi, Agostino; Crocetti, Letizia; Giovannoni, Maria Paola; Guerrini, Gabriella; Iacovone, Antonella; Kirpotina, Liliya N.; Ye, Richard D.; Quinn, Mark T. (2017). Synthesis of five and six-membered N-phenylacetamido substituted heterocycles as formyl peptide receptor agonists. DRUG DEVELOPMENT RESEARCH, vol. 78, pp. 49-62, ISSN:1098-2299 DOI  

  Guerrini, Gabriella; Ciciani, Giovanna; Crocetti, Letizia; Daniele, Simona; Ghelardini, Carla; Giovannoni, Maria Paola; Lorenzo Di Cesare Mannelli, ; Martini, Claudia; Vergelli, Claudia (2017). Synthesis and pharmacological evaluation of novel GABAA subtype receptor ligands with potential anxiolytic-like and anti-hyperlagesic effect. JOURNAL OF HETEROCYCLIC CHEMISTRY, vol. 54, pp. 2788-2799, ISSN:1943-5193 DOI  

  Vergelli, C; Schepetkin, I. A.; Crocetti, L.; Iacovone, A.; Giovannoni, M. P.; Guerrini, G.; Khlebnikov, A. I.; Ciattini, S.; Ciciani, G.; Quinn, M. T. (2017). Isoxazolo-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 821-831, ISSN:1475-6366 DOI  

  Vergelli, C; Schepetkin, I.A; Ciciani, G; Cilibrizzi, A; Crocetti, L; Giovannoni, M.P; Guerrini, G; Iacovone, A; Kirpotina, L.N; Khlebnikov, A.I; Ye, R.D; Quinn, M.T. (2016). 2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 2530-2543, ISSN:0968-0896

  Crocetti, Letizia; Schepetkin, Igor A.; Ciciani, Giovanna; Giovannoni, Maria Paola; Guerrini, Gabriella; Iacovone, Antonella; Khlebnikov, Andrei I.; Kirpotina, Liliya N.; Quinn, Mark T.; Vergelli, Claudia (2016). Synthesis and pharmacological evaluation of indole derivatives as deaza analogues of potent human neutrophil elastase inhibitors. DRUG DEVELOPMENT RESEARCH, vol. 77, pp. 285-299, ISSN:1098-2299 DOI  

  Giovannoni, Maria Paola; Crocetti, Letizia; Ciciani, Giovanna; Cilibrizzi, Agostino; Guerrini, Gabriella; Vergelli, Claudia (2016). Cinnoline derivatives as human neutrophil elastase inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 628-639, ISSN:1475-6366 DOI  

  Gabriella Guerrini; Giovanna Ciciani; Samuele Ciattini; Letizia Crocetti; Simona Daniele; Claudia Martini; Fabrizio Melani; Claudia Vergelli; Maria Paola Giovannoni (2016). Pyrazolo[1,5-a]quinazoline scaffold as 5-deaza analogue of pyrazolo[5,1-c][1,2,4]benzotriazine system: synthesis of new derivatives, biological activity on GABAA receptor subtype and molecular dynamic study. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 195-204, ISSN:1475-6366 DOI  

  Claudia Vergelli; Giovanna Ciciani; Agostino Cilibrizzi; Letizia Crocetti; Lorenzo Di Cesare Mannelli; Carla Ghelardini; Gabriella Guerrini; Antonella Iacovone; Maria Paola Giovannoni (2015). Synthesis of five and six-membered heterocycles bearing an arylpiperazinylalkyl side chain as orally active antinociceptive agents. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 6237-6245, ISSN:0968-0896

  M. P. Giovannoni;G. Ciciani;A. Cilibrizzi;L. Crocetti;S. Daniele;L. Di Cesare Mannelli;C. Ghelardini;C. Giacomelli;G. Guerrini;C. Martini;M. L. Trincavelli;C. Vergelli (2015). Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 89, pp. 32-41, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  L. Crocetti; C. Vergelli; A. Cilibrizzi; A. Graziano; A.I. Khlebnikov; L.N. Kirpotina; I.A. Schepetkin; M.T. Quinn; M.P. Giovannoni. (2013). Synthesis and pharmacological evaluation of new pyridazin-based thioderivatives as formyl peptide receptor (FPR) agonists. DRUG DEVELOPMENT RESEARCH, vol. 74, pp. 259-271, ISSN:0272-4391 DOI  

  M.P. Giovannoni; I.A. Schepetkin; A. Cilibrizzi; L. Crocetti; A.I. Khlebnikov; C. Dahlgren; A. Graziano; V. Dal Piaz; L.N. Kirpotina; S. Zerbinati; C. Vergelli; M.T. Quinn (2013). Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 64, pp. 512-528, ISSN:0223-5234 DOI  

  A. Cilibrizzi; L. Crocetti; M.P. Giovannoni; A. Graziano; C. Vergelli; G. Bartolucci; G. Soldani; M.T. Quinn; I.A. Schepetkin; C. Faggi. (2013). Synthesis, HPLC enantioresolution and X-ray analysis of a new series of C5-methyl pyridazines as N-formyl peptide receptor (FPR) agonists. CHIRALITY, vol. 25, pp. 400-408, ISSN:0899-0042 DOI  

  C. Vergelli; A. Cilibrizzi; L. Crocetti; A. Graziano; V. Dal Piaz; B. Wan; Y. Wang; S. Franzblau; MP Giovannoni. (2013). Synthesis and evaluation as antitubercular agents of 5-arylethenyl and 5-(hetero)aryl-3-isoxazolecarboxylate. DRUG DEVELOPMENT RESEARCH, vol. 74, pp. 162-172, ISSN:0272-4391 DOI  

  L. Crocetti; I.A. Schepetkin; A. Cilibrizzi; A. Graziano; C. Vergelli; D. Giomi; A.I. Klebnikov; M.T. Quinn; M.P. Giovannoni (2013). Optimization of N-benzoylindazole derivatives as inhibitors of human neutrophil elastase. JOURNAL OF MEDICINAL CHEMISTRY, vol. 56, pp. 6259-6272, ISSN:1520-4804

  A. Graziano; M.P. Giovannoni; A. Cilibrizzi; L. Crocetti; V. Dal Piaz; C. Vergelli; M.L. Trincavelli; C. Martini; C. Giacomelli (2012). New pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4-(3H)-ones fluoroderivatives as human A1 adenosine receptor ligands. ACTA CHIMICA SLOVENICA, vol. 59, pp. 648-655, ISSN:1318-0207

  A. Cilibrizzi; I.A. Schepetkin; G. Bartolucci; L. Crocetti; V. Dal Piaz; M.P. Giovannoni; A. Graziano; L. N. Kirpotina; M.T. Quinn; C. Vergelli (2012). Synthesis, enantioresolution and activity profile of chiral 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones as potent N-formyl peptide receptor agonists.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 20, pp. 3781-3792, ISSN:0968-0896 DOI  

  M.P. Giovannoni; A. Graziano; R. Matucci; M. Nesi; N. Cesari; C. Vergelli; C. Biancalani; L. Crocetti; A. Cilibrizzi; V. Dal Piaz (2011). Synthesis and evaluation as PDE4 inhibitors of pyrimidine-2,4-dione derivatives. DRUG DEVELOPMENT RESEARCH, vol. 72, pp. 274-288, ISSN:0272-4391 DOI  

  L. Crocetti; M.P. Giovannoni; I.A. Schepetkin; M.T. Quinn; A.I. Khlebnikov; A. Cilibrizzi; V. Dal Piaz; A. Graziano; C. Vergelli (2011). Design, synthesis and evaluation of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 19, pp. 4460-4472, ISSN:0968-0896 DOI  

  M. Giovannoni; C. Vergelli; A. Cilibrizzi; L. Crocetti; C. Biancalani; A. Graziano; V. Dal Piaz; M.I. Loza; M.I Cadavid; J. L. Diaz; A. Gavaldà (2010). Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A1 adenosine receptor ligands. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18, pp. 7890-7899, ISSN:0968-0896

  P.Biagini; C.Biancalani; A.Graziano; N.Cesari; M.Giovannoni; A.Cilibrizzi; V.Dal Piaz; C.Vergelli; L.Crocetti; M.Delcanale; E.Armani; A.Rizzi; P.Puccini; P.Gallo; D.Spinabelli; P.Caruso (2010). Functionalized pyrazoles and pyrazolo[3,4-d]pyridazinones: synthesis and evaluation of their phosphodiesterase 4 inhibitory activity. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18, pp. 3506-3517, ISSN:1464-3391