Su appuntamento

e-mail: annamaria.papini@unifi.it

cell: 3478844146

skype contact: pepthome

Education and Scientific Graduation

1977-1983: Italian “Laurea” in Chemistry, Curriculum Organic Chemistry & Chemical Biology of the University of Florence (Italy). Title of the “Laurea” thesis: Regioselective functionalisation of cyclic ethers and thioethers: synthesis of bifunctional derivatives via IVB organometallic compounds”.

1985-1989: International Ph.D. in Chemical Biology of the Italian Ministry of Education Title of the PhD thesis: . 1985-1986 Department of Biochemistry, University of Sherbrooke, Québec, Mentor Prof. Dr. Gilles Dupuis; 1986-1988 Dept. of Organic Chemistry, University of Florence, Mentor: Prof. Gianfranco. Rapi and 1988-1989 Department of Peptide Chemistry, Max Planck Institute für Biochemie, Martinsried Bei Muenchen, Mentor Prof. Dr. Luis Moroder. Title of the PhD thesis: “Synthesis of peptides for chemical, bio-pharmacological and immunological studies”.

1990 Specialisation in Dermatochemistry, Dermatological Department of the Florence University Hospital. Supervisor Pr. M.D. E. Panconesi.

2013-2019 and confirmed for 2018-2024: Habilitation to the function of Full Professor of Organic Chemistry of the Italian Universities.

Since 2001: Habilitation to the function of Full Professor of Organic Chemistry of the French Universities.

Curriculum vitae Anna Maria Papini, PhD

Scaricabile in versione italiana da https://www.peptlab.eu/media/profili/CV%20SITO%20GIUGNO%2020919_1.pdf

Who is interested to follow one of my lessons in Bioorganic Chemistry please copy this link into your browser

https://cloud.cla.unifi.it/owncloud/index.php/s/BKTPrYW6nS3SFTD

or Tape record of the talk: 

Theo Murphy International Scientific Discussion meeting at The Royal Society “Self-assembled peptides: from nanostructure to bioactivity” Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell, Buckinghamshire, MK16 9JJ (UK), October 24-25, 2016. Plenary Lecture October 25, 2016. Title: Autoimmunity and neurodegeneration: the mimicry pathway from aberrant N-glucosylated peptides to specific protein antigens.

http://downloads.royalsociety.org/events/2016/10/self-assembled-peptides/Papini.mp3

Education and Scientific Graduation

1977-1983: Italian “Laurea” in Chemistry, Curriculum Organic Chemistry & Chemical Biology of the University of Florence (Italy). Title of the “Laurea” thesis: Regioselective functionalisation of cyclic ethers and thioethers: synthesis of bifunctional derivatives via IVB organometallic compounds”.

1985-1989: International Ph.D. in Chemical Biology of the Italian Ministry of Education Title of the PhD thesis: . 1985-1986 Department of Biochemistry, University of Sherbrooke, Québec, Mentor Prof. Dr. Gilles Dupuis; 1986-1988 Dept. of Organic Chemistry, University of Florence, Mentor: Prof. Gianfranco. Rapi and 1988-1989 Department of Peptide Chemistry, Max Planck Institute für Biochemie, Martinsried Bei Muenchen, Mentor Prof. Dr. Luis Moroder. Title of the PhD thesis: “Synthesis of peptides for chemical, bio-pharmacological and immunological studies”.

1990 Specialisation in Dermatochemistry, Dermatological Department of the Florence University Hospital. Supervisor Pr. M.D. E. Panconesi.

2013-2019 and renewed for 2018-2024: Habilitation to the function of Full Professor of Organic Chemistry of the Italian Universities.

Since 2001: Habilitation to the function of Full Professor of Organic Chemistry of the French Universities.

Employment History

Since 2004 to date: Co-founder and head of the Interdepartmental Laboratory of Peptide & Protein Chemistry & Biology, Polo Scientifico of the University of Florence associating the Departments of Chemistry, Pharmaceutical Sciences & Neurosciences of the University of Florence.

Since 2010 to date: Founder and coordinator of the French-Italian Laboratory of Peptide & Protein Chemistry & Biology (www.peptlab.eu).

Since 2017 Associated to the CNR Institute IBB (Istituto di Biostrutture e Bioimmagini, Napoli and Catania).

Since 2010 to date: Founder and coordinator of the French-Italian Laboratory of Peptide & Protein Chemistry & Biology associating the Laboratory of Chemical Biology at the Université Paris-Seine, Cergy-Pontoise (France) and the Departments of Chemistry, Pharmaceutical Sciences & Neurosciences of the University of Florence (Italy) (www.peptlab.eu).

Since 2013 Founder and Director of the Platform PeptLab@UCP of the Université Paris-Seine, Cergy-Pontoise (France).

2001: Awarded Full Professor for the Chair of Organic Chemistry of the Claude Bernard University Lyon 1 (France). Waiver.

Since 2002 to date: Associate Professor and Chair of Bioorganic Chemistry of the University of Florence.

2001-2002: Researcher at the Department of Organic Chemistry, University of Florence.

1991-2001: “Tecnico Laureato” at the Department of Organic Chemistry of the University of Florence, associated to the Chair of Chemistry for the Medical School.

Teaching activities at the School of Mathematical, Physical, and Natural Sciences, Department of Chemistry, University of Florence

Chemistry of Biomolecules (6 CFU/ECTS, since 2010), “Laurea Magistrale” in Chemical Sciences, curriculum in Chemistry of Biological Molecules. Bioorganic Chemistry (6 CFU/ECTS, since 2010), “Laurea Magistrale” in Chemical Sciences, curriculum in synthesis, structure and reactivity of organic molecules. Laboratory of Organic Chemistry I, “Laurea triennale” in Chemistry (6 CFU, 2002-2007). Bioorganic Chemistry & Laboratory of Bioorganic Chemistry, “Laurea Specialistica” in Chemistry of Biological Molecules (6 CFU, 2007-2009).

Scientific contributions

1. www.peptlab.eu

Communication of the scientific activity

2001-2018: invited to present 116 lectures in International Symposia (keynotes, invited and plenary), Universities and Research Centres (EU, USA, Canada, Australia, Israel, Japan, China). 1997-2018: 52 oral & 242 poster communications were selected in international symposia and presented by her students or co-workers. 2009-2018: invited to present 10 lectures aimed to technology transfer in the global space of R&D (2 in extra-European countries and 8 in Europe).

Academic Roles and Responsabilities

Since 2013 Delegate of the International Affairs of the School of Sciences of the Uuniversity of Florence (Italy) and Responsible of the Erasmus + Exchanges Programmes for Study and Traineeship of the students incoming and outcoming (ca. 300 students/year) of the School of Sciences (Physics, Chemistry, Mathematics, Informatics, Biological and Natural Sciences, Earth sciences, Optics, Biotechnology, Cultural Heritage). Responsible of the Erasmus + Exchanges Programmes for Staff Teaching and Administrative Mobility.

Since 2005 Coordinator of the Erasmus Programme of Chemistry of the Faculty of Sciences of the University of Florence (Italy). Responsible of Erasmus Exchanges Programme for Study and Traineeship of the students of Chemistry.

2012 Member of the Committee for the selection of TFA A059 (Educational Trainings for teachers of chemistry in the secondary school).

2011 Representative of the Department of Chemistry of the University of Florence in the Pole of innovation for life sciences (“Polo d’Innovazione per le Scienze della Vita”.

Since 2010 Member of the Board of the PhD School in Chemical Sciences of the University of Florence.

2010-2014 Delegate of the Faculty of Sciences in the Board of the Foreign Language Centre (CLA - Centro Linguistico d’Ateneo) of the University of Florence.

2006-2016 Vice President and Delegate for Chemistry in the Board of OpenLab (Educational organisation of the Faculty of Sciences of the University of Florence.

2006-2009 Member of the Board of the PhD School in Non linear systems and complex dynamics of the University of Florence.

Awards for the scientific activity

2009-2014: Chaire d’excellence of the French Agence Nationale de la Recherche (unique of chemistry out of 16 attributed in 2009), ANR-09-CEXC-013-01, Project PepKit : Development of peptide-based-diagnostic kits for autoimmune diseases.

2008: Leonidas Zervas Award for outstanding contribution to peptide chemistry, 30th EPS, Helsinki (Finland), August 31, 2008.

2008: 1st D. Theodoropoulos Memorial Lecture Award for outstanding achievements in Peptide Sciences, 6th Hellenic Forum on Bioactive Peptides, Patras (Greece), May 18, 2008.

2006: Best Poster Award Lucio Senatore, XXII Congresso Nazionale della Società Chimica Italiana [V. Volkov, F. Nuti, Y.Takaoka, R. Chelli, A.M. Papini, and R. Righini. Structure and bonding of water molecules in the polar region of phospholipid membrane investigated by two-dimensional IR spectroscopy and MD computer simulation. XXII Congresso Nazionale della Società Chimica Italiana, Firenze, September 10-15, 2006, Abstract FIS-P-135] attributed to the work performed with the Postdoc student F. Nuti and of the coworker R. Chelli.

2005: Bert Schram Price. Honorable Mention, 19th American Peptide Symposium, San Diego, California, USA [B. Mulinacci, C. Breithaupt, P.P. Pal, N. Budisa, M. Pazzagli, B. Mazzanti, P. Rovero, L. Moroder, and A.M. Papini. Cross-reactivity studies of rMOGED with the synthetic putative autoantigen CSF114(Glc) and [N31(Glc)]hMOG(30-50) in Multiple Sclerosis patients’ sera. 19th American Peptide Symposium (San Diego, CA, USA), June 18-24, 2005, LY 03, Abstract p. 484] attributed to the work performed with the PhD student B. Mulinacci.

2005: Best Poster Award Glycoconjugates “Glyco XVIII”, Florence, Italy [F. Nuti, I. Paolini, B.Mulinacci, M. Pazzagli, F. Lolli, M. Chelli, P. Rovero, and A.M. Papini. Sugar-scan of CSF114(Glc) for autoantibody recognition in Multiple Sclerosis. XVIII International Symposium on Glycoconjugates. Glyco XVIII”, Firenze, September 4-9, 2005, Abstract P057, Glycoconjugate J., 2005, 22(4–6), 254] attributed to the work performed with the PhD student F. Nuti.

1999: Bruce W. Erickson Award for outstanding achievement in peptide sciences, 16th American Peptide Symposium, Minneapolis, Minnesota, USA [E. Nardi, S. Mazzucco, S. Matà, M. Chelli, B. Mazzanti, E. Traggiai, M. Ginanneschi, F. Pinto, L. Massacesi, M. Vergelli, H. Kalbacher, F. Lolli and A.M. Papini. Influence of different N-linked glycosyl moiety at position 31 of hMOG(30-50) on anti-MOG antibody recognition in multiple sclerosis patients. 16th American Peptide Symposium, Minneapolis (Minnesota, USA), June 26-July 1, 1999, Abstract P148] attributed to the work performed with the PhD student E. Nardi.

Awards for the technology transfer activity

2009: Vespucci Award for founding the startup Toscana Biomarkers.

2008: Frost & Sullivan Excellence in Research Award in the European autoimmune disease diagnostics market presented to AMP for the startup Toscana Biomarkers.

2006: Start-Cup for business plan of the start-up Toscana Biomarkers.

2004: Vespucci Award, Research & Ethical Innovation to AMP as inventor of PCT (2003) WO 03000733 A2.

Technology transfer activity

Since 2017 Founder and Scientific Coordinator of PeptFarm “Laboratorio congiunto Università di Firenze – Impresa” joining PeptLab and Fabbrica Italiana Sintetici, F.I.S. Italy to develop large-scale synthesis of peptide-drugs.

2016: Founder of the spin-off company Apotech for R&D of peptide-based cosmeceutics.

Since 2014 Member of the Scientific Advisory Board of Regulaxis (www.regulaxis.com)

2007-2015: Founder & Chief Scientific Officer of the startup Toscana Biomarkers

Since 2003: Founder and member of the Board of EspiKem, 1st spinoff of the University of Florence

Recent Research Funding

2017-2019: “Regione Toscana POR CReO FESR 2014-2020”. EcoReLabel: Ecological removable and recyclable labels. 303.000,00 Euro

2010-2012: “Regione Toscana POR CReO FESR 2007-2013”. MARK: Identification of diagnostic biomarkers of autoimmune diseases.450.000,00 Euro.

2005-2011: “Fondazione Cassa di Risparmio di Firenze”. Molecular characterisation of peptide-protein interaction in autoimmune diseases. 1.500.000 Euro for PeptLab at University of Florence.

2005-2007: International FIRB- Italian Ministry of University & Research and Harvard Medical School. 350.000,00 Euro.

2002-2003, 2005-2006, 2008-2009: PRIN-Italian Ministry of University & Research. Design, synthesis & immunological characterisation of modified peptides to follow up autoimmune diseases. 700.000,00 Euro.

2009-2014: “Chaire d’Excellence” (ANR-09-CEXC-013-01). PepKit: Development of peptide-based-diagnostic kits for autoimmune diseases. 999.998,00 Euro for the PeptLab@UCP platform.

2016-2018 Lauréate MRSEI-ANR Edition 2015, Project REDIPOC to organize and submit a FET-OPEN project by January 2017 for a Reliable Diagnostic Point Of Care Network, 20.000 Euro.

2013-2016 PhD grant CIFRE in cooperation with REGULAXIS, 90.000 Euro.

2015-2018 BIRAC, Indo-French Challenge-oriented Call for proposals 2014 : AMIR-PepKit IVD, R&D of a peptide-based-diagnostic kit for for an early detection of a fatal immune response in acute myocardial infarction patients. 50.000 Euro.

2011-2013: “Fondation Pierre-Gilles de Gennes”. Immune-mediated diseases: Glycopeptidomic-based diagnostics to follow-up disease activity. 2 post-doctoral fellows + 90.000 Euro for materials.

Panel Member of international evaluation committees attended personally

2012-2016: Panel Member for ERC Advanced Grant evaluation PE5 – Synthetic chemistry and materials, Brussels (attended 3 panels, 2 meetings every two years).

24-29 September 2018: Panel member as expert of bioorganic chemistry and chemical biology for assessment of research and development of the universities and research institutions of Lithuania in the field of physical sciences.

26-27 July 2018: Panel member of the Foundation for Polish Science to select the winners of the First Team programme, edition 5/2018, Warsaw (Poland).

6-7 December 2017: Vice-president of the French High Council for Evaluation of Research and Higher Education (HCERES) evaluation committee Group D of the Unit Molecules of Communication and Adaptation of Microorganisms (MCAM) UMR 7245 CNRS Muséum National d’Histoire Naturelle (MNHN).

2016-2019 Elected member of the “Conseil Nationale des Universités” - CNU (France) to deliberate habilitations and promotions of the French University researchers and professors.

2016: Member of the evaluation panel for Promotion of Research and Development Programmes Implementation for the Ministry of Education, Science, and Sport, Republic of Slovenia.

February 2011: Member of the AERES Committee for evaluation of the ICM of the University of Reims.

2011-2012 Member of the Evaluation Committee of research projects submitted to the Fondation de la Recherche Médicale, France.

March 2010: Member of the AERES Committee for evaluation of iBiTecc-S Equipe SIMOPRO (CEA, Saclay).

Since 2010 Member of the Council of “Ordine dei Chimici della Toscana” (Society of Chemists in Tuscany).

Remote Referee of international evaluation committees

2017 Nominee member expert by the German-Israeli Foundation (GIF) for Scientific Research and Development to evaluate projects presented at the GIF Regular Program.

2016 External Member of an “Ad Hoc Committee” for promotion review at The Scripps Research Institute (TSRI) of candidates to the rank of Associate Professor with Tenure.

2016 Nominee evaluator for research projects submitted to the United States – Israel Binational Science Foundation (BSF).

2016 Nominee External evaluator of candidates for Faculty Positions in the subject field: “Organic Chemistry with emphasis on Chemistry” at the University of Patras (Greece).

2015-2016 Nominee Reviewer for research projects submitted to the executive government agency of the Polish National Science Centre (Narodowe Centrum Nauki - NCN; http://www.ncn.gov.pl).

2014 Nominee reviewer by “Vienna Science and Technology Fund (VSTF, Austria)” to evaluate proposals submitted to the Vienna Research Groups for Young Investigators call in the field of “Life Sciences”.

2014 Nominee Reviewer by the National Science Centre in Poland (Narodowe Centrum Nauki - NCN; http://www.ncn.gov.pl) to evaluate projects in the Funding scheme PRELUDIUM.

2011-2013 Nominee reviewer by the “Association Nationale Recherche et Technologie (ANRT, Paris, France) to evaluate proposals CIFRE (Conventions Industrielles de Formation par la Recherche) to fund PhD 50% in industrial environments.

Activity as delegate, panel member and evaluator in Italy

2012-2017 Referee for the Evaluation of the quality of the research of the Italian Universities (VqR )

2012 Member of the Committee for the selection of TFA A059 (Educational Trainings for teachers of chemistry in the secondary school)

2011-2015 Representative of the Department of Chemistry of the University of Florence in the Pole of innovation for life sciences (“Polo d’Innovazione per le Scienze della Vita”.

2010-2014 Delegate of the Faculty of Sciences in the Board of the Foreign Language Centre (CLA - Centro Linguistico d’Ateneo) of the University of Florence.

2010-2020 Member of the Council of “Ordine dei Chimici della Toscana” (Society of Chemists in Tuscany).

2006-2016 Vice President and Delegate for Chemistry in the Board of OpenLab (Educational organisation of the Faculty of Sciences of the University of Florence.

Since 2010 Member of the Board of the PhD School in Chemical Sciences of the University of Florence.

2006-2009 Member of the Board of the PhD School in Non linear systems and complex dynamics of the University of Florence.

2012-2017 Referee for the Evaluation of the quality of the research of the Italian Universities (VqR )

Organisation of international Symposia

2016: Nominee Chairperson of the 14th International Peptide Symposium and 37th European Peptide Symposium that will be held in Florence (Italy), 28 August-2 September 2022.

2016: Chairperson of the 2016 GRC: Chemistry & Biology of Peptides: Crossing Barriers by Peptide Science for Health and Wellness, with Prof. Dr. P. Dawson, Ventura, CA (USA), 21-26/02/2016

2014: Vice-chair of the GRC: Chemistry & Biology of Peptides: Peptide Science in the Era of Synthetic Biology, Ventura, CA (USA), 23-28/02/2014.

2016: Chairperson of 1st Mass Spectrometry Peptide Day, Convento di Sant’Apollonia, Firenze, 10-12 February 2016 (http://www.spettrometriadimassa.it/Congressi/1MS-PeptideDay/)

2014: Chairperson of the International Symposium Peptides in Paris PIPS 2014 and Training Course 5-10 October 2014. Co-editor of the special issue in Biopolymers Peptide Science together with S. Lavielle (UPMC, Paris) and W.D. Lubell (Université de Montreal).

2014: Responsible of the thematic semester “Peptides & Proteins Molecules of Life. Université de Cergy Pontoise (France) as final event of the Chaire d’Excellence 2009-2014.

2011: Chair of the Symposium "PEPTIDES AND PROTEINS IN THE NEW MILLENNIUM" organised in honour of the Doctorate Honoris Causa attributed from the Université de Cergy-Pontoise to Prof. Luis Moroder in Neuville-sur-Oise (France), 5-6 October, 2011.

2011: Microwave-Assisted Organic Peptie Synthesis (MAOPS2), Chiostro del Maglio, Firenze (Italy), 26-28 April 2011.

2010: 1ST ITALY-AUSTRALIA PEPTIDE SYMPOSIUM ON BIOMOLECULES FOR DIAGNOSTICS & THERAPEUTICS, Satellite of 31st European Peptide Symposium, Monash University, Prato (Italy), 10-12 September, 2010.

2007: EUROCOMBI4, 1ST INTERNATIONAL SYMPOSIUM ON COMBINATORIAL SCIENCES IN BIOLOGY, CHEMISTRY, CATALYSTS AND MATERIALS, Chiostro del Maglio, Firenze (Italy), 15-18 July, 2007.

2006: INTERNATIONAL TRAINING COURSE ON MASS SPECTROMETRY & HIGH PERFORMANCE LIQUID CHROMATOGRAPHY OF PROTEINS (sponsored by UNESCO), Polo Scientifico, Università di Firenze, 1-12 May 2006.

2003: 1ST PRACTICAL TRAINING COURSE: INNOVATIVE COMBINATORIAL APPROACHES AND TECHNOLOGIES (sponsored by European Society of Combinatorial Sciences,) Polo Scientifico, Università di Firenze, 9-11 April, 2003.

Member of scientific committees of international symposia

2018: Member of the Scientific Committee of the 16th Naples Workshop on Bioactive Peptides, Naples (Italy) June 7-9, 2018.

2017: Nominee member of the Advisory Committee of the American Peptide Symposium 2019, Monterey, CA, USA, June 22-27, 2019.

2017: Nominee member of the Organising Committee of the European Chemistry Conference, Roma (Italy) June 11-13, 2018.

2016: 34th European Peptide Symposium, Leipzig (Germany); 2014: 33rd European Peptide Symposium, Sofia (Bulgaria), 2010: 31st European Peptide Symposium, Copenhagen (Denmark).

2009: SCS-09 2nd International Symposium on Combinatorial Sciences in Biology, Chemistry, Catalysts and Materials, Bejing (China).

2002 and 2004: 2nd, 3rd and 5th Medicinal Chemistry Conference: Drug discovery and Design, University of Patras (Greece).

Member of international evaluation and selection committees of PhD and habilitation exams 

August-September 2018 Member of the selection committee of the 34thPhD Course in Chemical Sciences of the University of Florence (Italy).

2010, 2012 & 2013 Referee at Ecole Doctorale Université Pierre et Marie Curie, Paris (France)

2010 Referee at Ecole Doctorale Université Montpellier 2

2009 Referee at Ecole Doctorale Université de Bourgogne

2008, 2010 & 2011 Referee at Ecole Doctorale Université de Strasbourg

2011, 2016 & 2016 Referee at Ecole Doctorale Université Paris-Sud (France)

2012 Referee at PhD School University of Montreal (Canada).

Referee of “Habilitations à diriger les recherches” (HDR)

2008 University of Strasbourg (France)

2011 Université Pierre et Marie Curie, Paris (France).

Activities as Visiting Professor/Scientist

2018 Erasmus Teaching Mobility at the University of Wroclaw (Poland)

2016 Erasmus Teaching Mobility at the University of Wroclaw (Poland)

2010 Erasmus Teaching Mobility at the University of Bolu (Turkey)

2010 Erasmus Teaching Mobility at the University of Balikesir (Turkey)

2010 Erasmus Teaching Mobility at the University of Patras (Greece)

2010 Erasmus Teaching Mobility at the University of Gdansk (Poland)

2008 Invited Professor at the Université de Cergy-Pontoise (France)

2008 Invited Professor at the Université de Bourgogne, Dijon (France)

2005 Invited Professor of Organic Chemistry at the Université de Bourgogne, Dijon (France)

1999 Visiting Scientist at the Medizinisch Naturwissenschaftlichens Forschungs Zentrum, University of Tuebingen (Germany)

1998-1999 Invited Professor of Organic Chemistry, U.F.R. Sciences et Techniques, Neuville sur Oise, Université de Cergy-Pontoise (France)

Innovative Teaching and Dissemination Activities in Italy

2010-2012 Director of the “Corso di Specializzazione per la Professione di Chimico”, Faculty of Sciences of the University of Florence in cooperation with Ordine dei Chimici della Toscana.

2010 and 2011 Organiser of the Course “Rischio Chimico” for VVFF (Vigili del Fuoco) in the Regione Toscana in cooperation with OpenLab and Ordine dei Chimici della Toscana

2010 Organiser of the Course “Mass Spectrometry” for VVFF (Vigili del Fuoco) in the Regione Toscana in cooperation with OpenLab and Ordine dei Chimici della Toscana.

2002-2003 Member of the Board and teaching activity in the Master 2nd level “Innovative Synthetic Methodologies” of the Faculty of Sciences of the University of Florence.

2002 Member of the Organising Board of the Open day of the Department of Chemistry XII Week of Scientific Culture in Tuscany.

Since 2001 Organiser of Chemistry Activities for OpenLab – Dissemination of Science at the Polo Scientifico e Tecnologico of the University of Florence for students from 3 to 18 years old of the Schools in Tuscany.

1986-1990 Trainer of Chemistry for Teachers of Primary Schools in the Project IRRSAE in Tuscany.

Supervisor of diploma/master/bachelor and PhD theses

Supervisor of 20 finalized PhD theses in Chemical Sciences and 5 ongoing, 47 finalised master theses and 3 ongoing in Chemical Sciences, supervisor of 22 Bachelor students and 1 ongoing. Tutor of Erasmus students: 19 Traineeship for periods going from 4 months till 1 year, 14 Master and 5 PhD students.

Snap-shot of the group (as of September 2018, IT & FR)

4 PhDs; 5 Post-docs; 1 Senior Researcher; 3 Associate Professors (1 IT and 2FR); 5 Master students; 6 Bachelor students; 4 Erasmus traineeship students. Since March 2017 the Rita Levi Montalcini 2014 Recipient Dr Claudia Bello joined PeptLab at the University of Florence with the tenure track position RTDb.

Editorial Advisory Board Member

Since 2005 Editor-for-Europe of Protein & Peptide Letters, Bentham Science Publishers Ltd.

Since 2004 Current Drug Delivery, Bentham Science Publishers Ltd. Since 2005 International Journal of Peptide Research and Therapeutics.

Since 2009 Member of the Editorial Advisory Board of Journal of Peptide Science, Wiley Publisher.

Since 2013 Member of the Editorial Advisory Board of Current Protein & Peptide Science, Bentham Science Publishers Ltd.

Since 2003 Member of the Editorial Advisory Board of International Journal of Peptide Research and Therapeutics, Springer

Since 2017 Member of the Editorial Board di Biosensors – Open Access Jounal MDPI (ISSN 2079-6374; CODEN: BIOSHU

Since 2018 Review Editor of Frontiers in Chemistry – Chemical Biology Open access publisher

Since 2018: Associate Editor of Current Peptide and Protein Sciences, Bentham Science Publishers Ltd.

2007-2016 Member of the Editorial Board of Chemistry Today, Editor Teknoscienze

Member of the board of scientific societies

2011-2020: Treasurer and member of the Board of the European Peptide Society.

2017-2020: Nominee Member of the Scientific Committee of the Italian Peptide Society

2004-2008: Nominee Member of the Scientific Affairs Committee of the European Peptide Society.

2000-2013: Nominee academic representative for Italy in the Board of the Society of Combinatorial Chemistry.

Scientific Societies Membership

Since 1988: Charter Member of the American Peptide Society.

Since 1988: Member of the European Peptide Society. Since 1988: Member of the Federation of American Societies for Experimental Biology.

Since 2000: Member of the Society of Combinatorial Sciences.

Since 1993: Charter Member of the Division of Chemistry of Biological Systems of the Italian Society of Chemistry.

Since 2016: Founder and member of the Italian Peptide Society

Scientific Fields of interest

Peptide and protein organic chemistry. Development of innovative synthetic solid-phase strategies. Microwave assisted peptide synthesis. Bioorganic chemistry of peptides and proteins. Synthetic & semi-synthetic strategies of co- or post-translationally modified proteins. Unnatural amino acids orthogonally protected for peptide synthesis (constrained amino acids, glycosyl and lipophilic amino acids). Coupling reagents for peptide chemistry (amide and ester bond formation).

Synthetic biology. Production of proteins specifically glycosylated, such as glucosylated adhesin protein from Haemophilus influenzae. Expression of cell-surface adhesins including N-Glc, to establish a connection between H. influenzae infection and autoimmune diseases, such as Multiple Sclerosis. We exploited the biosynthetic machinery from the opportunistic pathogen H. influenzae (and the homologous enzymes from A. pleuropneumoniae) to produce a unique set of defined glucosylated adhesin proteins to detect specific and high affinity antibodies.

Industrial applications

In vitro Diagnostics and peptide biomarkers. Autoimmune diseases. Molecular mechanisms of immune-mediated autoimmune diseases. Cross-reaction with infectious diseases. Glycoconjugates as diagnostic and prognostic tools for human, animal, and plant diseases. Diagnosis and therapy of autoimmune diseases: role of co- or post-translational modifications of myelin proteins and peptides for immunological studies on multiple sclerosis for the development of diagnostic/prognostic tools, innovative immunotherapies and characterisation of biomarkers of disease activity. Apheresis technologies. In vivo Diagnostics and imaging techniques. DOTA peptide analogues for cancer pre-targeting diagnosis & therapy. FIV peptides for the development of an anti-retroviral therapy for felines. Cultural heritage. Peptide-based immunoassays for characterization of glues, in particular collagen. Peptide Nutraceuticals and cosmeceutics. Spiruline. Fish feed. Peptides involved in collagen turnover. Development of processes for large scale solid-phase peptide synthesis. GMP production of active peptides as pharmaceutical ingredients. MW-technology. Peptide materials.

Anna Maria Papini was born in Firenze (Italy) on February 2, 1959. Married with 2 daughters Giulia (born in 1991) and Elena (born in 1996). French and Italian nationality. Bilingual: French and Italian mother tongues. Language skills: English and German.

 September 10, 2018

Scientific contributions

Anna Maria Papini contributed with 251 scientific publications: 143 peer-reviewed articles in scientific journals, 108 peer-reviewed articles in books, 10 International Patents. Bibliometric indicators (22-06-2018): Results found: 142 (Scopus) and 278 (WoS). Sum of the Times Cited: 2022 (Scopus), 2005 (WoS). h-index: 26 (Scopus), 25 (WoS). Full paper list is available at www.peptlab.eu

Communication of the scientific activity

2001-2018: invited to present 116 lectures in International Symposia (keynotes, invited and plenary), Universities and Research Centres (EU, USA, Canada, Australia, Israel, Japan, China). 1997-2018: 52 oral & 242 poster communications were selected in international symposia and presented by her students or co-workers. 2009-2018: invited to present 10 lectures aimed to technology transfer in the global space of R&D (2 in extra-European countries and 8 in Europe).

Publications in peer-reviewed scientific journals (1983-2018)

1983-1990

[1] M. Taddei, A.M. Papini, M. Fiorenza, A. Ricci and G. Seconi. Ring opening reactions of thiiranes with group IVB organometallics: a new regioselective route to b-amino and b-cyanide thiols. Tetrahedron Lett. (1983) 24, 2311-2314. Pubblicato a Oxford, Gran Bretagna, Maggio 1983.

[2] A.M. Papini, A. Ricci, M. Taddei, G. Seconi and P. Dembech. Regiospecific Conversion of Oxiranes, Oxetanes, and Lactones into Difunctional Nitrogen Compounds via Aminosilanes and Aminostannanes. J. Chem. Soc. Perkin Trans. I (1984)2261-2265. Pubblicato a Cambridge, gran Bretagna, Ottobre 1984.

[3] S. Francalanci, S. Giorgini, M. Gola, M. Ginanneschi, A.M. Papini and A. Sertoli. Eczema da contatto da antifungino topico. Boll. Dermatol. Allergol. e professionale (1986) 1, 9-13.

[3] M. Ginanneschi, A. Sertoli, A.M. Papini and G. Rapi. Chemical aspects of hapten-carrier interaction in contact allergy. Giorn. It. Derm. Vener. (1987) 122, 389-395. PubMed ID 3666799.

[4] S. Giuliani, R. Amann, A.M. Papini, C.A. Maggi and A. Meli. Modulatory action of galanin on responses due to antidromic activation of peripheral terminals of capsaicin-sensitive sensory nerves. Eur. J. Pharmacol. (1989) 163, 91-96. Pubblicato a Amsterdam, olanda, Aprile 1989.

[5] M. Ginanneschi, M. Chelli, A.M. Papini and G. Rapi. Highly efficient synthesis of steroid-17-spiro-5’-oxazolidine-2’,4’-diones from 17-keto steroids. Steroids (1990) 55, 501-506. Pubblicato a Stoneham, Massachusetts (U.S.A.), Novembre 1990.

[6] M. Chelli, G. Dupuis, S. Evangelista, M. Ginanneschi, A. Meli, A.M. Papini and G. Rapi. Suppression of the skin response to alantolactone in alantolactone-sensitized guinea pigs treated with N-acetyl-l-cysteinyl-l-alanine methyl ester. Eur. J. Med. Chem. (1990) 25, 107-115. Pubblicato a Parigi, Francia, Marzo 1990.

1991-1998

[7] R. von Grünigen, G. Siglmüller, A.M. Papini, K. Köcher, B. Traving, W. Göhring and L. Moroder. Enzyme Immunoassay with Captured Hapten. A sensitive Gastrin Assay with Biotinyl-Gastrin Derivatives. Biol. Chem. Hoppe-Seyler (1991) 372, 163-172. Pubblicato a Berlino, Germania, Marzo 1991. Oggi Biol. Chem.

[8] A.M. Papini, S. Rudolph, G. Siglmüller, H.-J. Musiol, W. Göhring and L. Moroder. Alkylation of histidine with maleimido-compounds. Int. J. Pept. Prot. Res. (1992) 39, 348-355. Pubblicato a copenhagen, Danimarca, Aprile 1992. Oggi J. Pept. Res.

[9] D. Donati, M. Ginanneschi, M. Chelli, G. Rapi and A.M. Papini. X-ray structure analysis of 3,11,17-trioxoandrostane-5a-carbonitrile and of 17a-ethoxycarbonyloxy-3-oxoandrost-4-ene-17-carbonitrile. Steroids (1992) 57, 502-506. Pubblicato a Stoneham, Massachusetts (U.S.A.), Ottobre 1992.

[10] L. Moroder, A.M. Papini, G. Siglmüller, K. Köcher, E. Dörrer and C.H. Schneider. Induction and Detection of Anti-Peptide Antibody Specificity Is Critically Affected by the Mode of Hapten Presentation. Biol. Chem. Hoppe-Seyler (1992) 373, 315-321. Pubblicato a Berlino, Germania, Giugno 1992. Oggi Biol. Chem.

[11] M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani and G. Rapi. Cyclization of C-Terminal Histidine Peptides to 7-Amino-dihydroimidazo[1,5-c]pyrimidin-5-one Derivatives. J. Chem. Research (S) (1993) 118-119. Pubblicato a Cambridge, gran Bretagna, Marzo 1993.

[12] M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani, G. Rapi, E. Borghi, F. Laschi and M. Occhiuzzi. Complexation Properties of Histidyl-Glycyl-Containing Peptides. Part 1. Synthesis of cyclo(L-His-Gly)4 J. Chem. Research (S) (1993) 437-438 and J. Chem. Res.(M) (1993) 2929-2938. Pubblicato a Cambridge, gran Bretagna, Novembre 1993.

[13] E. Borghi, F. Laschi, M. Occhiuzzi, M. Chelli, M. Ginanneschi, A.M. Papini and G. Rapi. Complexation Properties of Histidyl-Glycyl containing Peptides. Part 2. An X-band EPR Study of Divalent Paramagnetic Metal Ions Interacting in Solution with H-(L-His-Gly)2-OMe. J. Chem. Research (S) (1994) 48-49. Pubblicato a Cambridge, gran Bretagna, Gennaio 1994.

[14] D. Pinzani, A.M. Papini, M. Chelli, M. Ginanneschi, C.A. Maggi, R. Patacchini, L. Quartara and G. Rapi. Synthesis and biological activity of tachykinin analogs containing the adamantane moiety. Lett. Pept. Sci. (1995), 2, 307-313. Pubblicato a Leiden, olanda, Febbraio 1996.

[15] M. Ginanneschi, M. Chelli, A.M. Papini, D. Pinzani and G. Rapi. Structure of the adduct of Alantolactone with Z-l-Cys-l-Ala-OMe and 1H and 13C assignment of the Alantolactone moiety by 14 Tesla NMR. Magn. Reson. Chem.(1996) 34, 95-99. Pubblicato a Chichester, W. Sussex, Inghilterra, Febbraio 1996.

[16] D. Pinzani, A.M. Papini, M.E. Vallecchi, M. Chelli, M. Ginanneschi, G. Rapi, L. Quartara, R. Patacchini, C.A. Maggi and F.M. Arcamone. Glycosyl derivatives of NK2 tachykinin receptor antagonists. Bioorg. Med. Chem. Lett.(1996) 6, 367-372. Pubblicato a Kidlington, Oxford, Inghilterra, Febbraio 1996.

[17] G. Giorgi, M. Ginanneschi, M. Chelli, A.M. Papini, F. Laschi and E. Borghi. Histidyl-Glycyl containing peptides. Characterization and complexation properties of H(L-His-Gly)₂-R with hydrogen and alkali metal ions in the gas-phase. Rapid Commun. Mass Spectrom. (1996) 10, 1266-1272. Pubblicato a Chichester, W. Sussex, Inghilterra, Ottobre 1996.

[18] G. Caminati, A.M. Papini, S. Mazzucco and G. Gabrielli. Lipopeptides of myelin basic protein in mono- and multilayers. Thin Solid Films (1998) 327-329(1-2), 37-41. Pubblicato a Kidlington, Oxford, Inghilterra, 31 Agosto 1998.

[19] M. Ciuffi, C. Cellai, S. Franchi-Micheli, P. Failli, L. Zilletti, M. Ginanneschi, M. Chelli, A.M. Papini and F. Paoletti. An in vivo, ex vivo and in vitro comparative study of activity of copper oligopeptide complexes vs Cu(II) ions. Pharmacol. Res. (1998) 38, 279-287. Pubblicato a Londra, Gran Bretagna, febbraio 1998.

1999

[20] S. Mazzucco, E. Nardi, M. Chelli, M. Ginanneschi, G. Rapi, A.M. Papini, M. Vergelli, B. Mazzanti, L. Massacesi and L. Amaducci. Synthesis of lipopeptides of the immunodominant epitope hMBP(83-99) containing amide or C-C bond linked hydrophobic chains for the study of T cell response. Lett. Pept. Sci. (1999) 6, 51-59. Pubblicato a Dordrecht, Olanda, Gennaio 1999.

[21] G. Sabatino, M. Chelli, S. Mazzucco, M. Ginanneschi and A M. Papini. Cyclisation of Histidine Containing Peptides in the Solid-Phase by Anchoring the Imidazole Ring to Trityl Resins. Tetrahedron Lett. (1999) 40(4), 809-812. Pubblicato a Oxford, Gran Bretagna, Gennaio 1999.

[22] S. Mazzucco, S. Matà, M. Vergelli, R. Fioresi, E. Nardi, B. Mazzanti, M. Chelli, F. Lolli, M. Ginanneschi, F. Pinto, L. Massacesi and A.M. Papini. A Synthetic Glycopeptide of Human Myelin Oligodendrocyte Glycoprotein to Detect Antibody Responses in Multiple Sclerosis and Other Neurological Diseases. Bioorg. Med. Chem. Lett. (1999) 9(2), 167-172. Pubblicato a Kidlington, Oxford, Gran Bretagna, Gennaio 1999.

[23] M. Casolaro, M. Chelli, M. Ginanneschi, F. Laschi, M. Muniz-Miranda, A.M. Papini and G. Sbrana. Spectroscopic and potentiometric study of copper(ii) complexes with l-histidyl-glycyl-l-histidyl-glycine in aqueous solution. Spectrochim. Acta Part A, Mol. & Biomol. Spectroscopy (1999) 55(7-8), 1675-1689. Pubblicato a Kidlington, Oxford, Gran Bretagna, Luglio-Agosto 1999.

[24] C. Galoppini, S. Meini, M. Tancredi, A. Di Fenza, A. Triolo, L. Quartara, C.A. Maggi, F. Formaggio, C. Toniolo, S. Mazzucco, A.M. Papini and P. Rovero. A new class of pseudopeptide antagonists of the kinin B1 receptor containing alkyl spacers. J. Med. Chem. (1999) 42(3), 409-414. Pubblicato in U.S.A., 11 Febbraio 1999.

2001

[25] C. Giragossian, E. Nardi, C. Savery, M. Pellegrini, S. Meini, C.A. Maggi, A.M. Papini, and D. Mierke. Structural Characterization of Lipopeptide Agonists for the Bradykinin B2 Receptor. Biopolymers (2001) 58, 511-520.

[26] A.M. Papini, B. Mazzanti, E. Nardi, E. Traggiai, C. Ballerini, T. Biagioli, H. Kalbacher, H. Beck, M. Deeg, M. Chelli, M. Ginanneschi, L. Massacesi, and M. Vergelli. Palmitoyl Derivatives of GpMBP Epitopes: T-Cell Response and Peptidases Susceptibility. J. Med. Chem. (2001) 44, 3504-3510.

[27] F. Meyer, J. Uziel, A.M. Papini, and S. Jugé. Triphenylphosphonium salts bearing an l-alanyl substituents: short synthesis and enantiomeric analysis by NMR. Tetrahedron Lett. (2001) 42, 3981-3984.

[28] A. Carotenuto, A.M. D’Ursi, E. Nardi, A.M. Papini, and P. Rovero. Conformational analysis of a glycosylated Human Oligodendrocyte Glycoprotein peptide epitope able to detect antibody response in Multiple Sclerosis. J. Med. Chem. (2001), 44, 2378-2381.

2002

[29] E. Peroni, G. Caminati, P. Baglioni, F. Nuti, M. Chelli,and A.M. Papini. A New lipophilic fluorescent probe for interaction studies of bioactive lipopeptides with membrane models. Bioorg. Med. Chem. Lett. (2002) 12, 1731-1734.

[30] M. Casolaro, M. Chelli, M. Ginanneschi, F. Laschi, L. Messori, M. Muniz-Miranda, A.M. Papini, T. Kowalik-Jankowska, and H. Kozlowski. Spectroscopic and potentiometric study of the SOD mimic system Copper/Acetyl-L-histidyl-glycyl-L-histidyl-glycine. J. Inorganic Biochem. (2002) 89, 181-190.

[31] A.M. Papini,E. Nardi, F. Nuti, J. Uziel, M. Ginanneschi, M. Chelli, and A. Brandi. Diastereoselective alkylation of Schiff bases for the synthesis of lipidic unnatural Fmoc-protected a-amino acids. Eur. J. Org. Chem. (2002) 16, 2736-2741.

[32] C. Giragossian, S. Stone, A.M. Papini, L. Moroder, and D.F. Mierke. Conformational and molecular modeling studies of sulfated cholecystokinin-15. Biochem. Biophys. Res. Commun. (2002) 293, 1053-1059.

[33] G. Sabatino, B. Mulinacci, M.C. Alcaro, M. Chelli, P. Rovero, and A.M. Papini. Assessment of new 6Cl-HOBt based coupling reagents for peptide synthesis. Part 1: Coupling efficiency study. Lett. Pept. Sci. (2002) 9, 119-123.

2003

[34] G. Sabatino, M. Chinol, G. Paganelli, S. Papi, M. Chelli, G. Leone, A.M. Papini, A. De Luca, and M. Ginanneschi. ANew Biotin Derivative-DOTA Conjugate as a candidate for pre-targeted diagnosis and therapy of tumors. J. Med. Chem. (2003) 46, 3170-3173.

[35] M.C. Alcaro, M. Orfei, M. Chelli, M. Ginanneschi, and A.M. Papini. Solid-phase approach to the synthesis of cyclen derivatives from cyclotetrapeptides. Tetrahedron Letters (2003) 44, 5217-5219.

[36] F. Meyer, A. Laaziri,A.M. Papini, J. Uziel, and S. Jugé. Efficient synthesis of b-halogeno protected L-alanines and their b-phosphonium derivatives. Tetrahedron Asymmetry (2003) 14,2229-2238.

[37]A.M. Papini, and P. Rovero. A combinatorial approach towards a diagnostic tool for MS. Speciality Chemicals Magazine (2003) 23(7), 26-27. Chem. Abs., 2003, 140, 355261.

[38] M.C. Alcaro, E. Peroni, P. Rovero, and A.M. Papini. Synthetic peptides in the diagnosis of HIV infection. Current Protein and Peptide Science (2003) 4, 285-290. Chem. Abs., 2003, 139, 212483.

[39] F. Lolli, B. Mazzanti, P. Rovero, and A.M. Papini. Synthetic peptides in the diagnosis of neurological diseases. Current Protein and Peptide Science (2003) 4, 277-284. Chem. Abs., 2003, 140, 283516.

2004

[40] M.C. Alcaro, G. Sabatino, J. Uziel, M. Chelli, M. Ginanneschi, P. Rovero, and A.M. Papini.On-resin head-to-tail cyclization of cyclotetrapeptides: optimization of crucial parameters. J. Peptide Science (2004)10(4), 218-228. DOI: 10.1002/psc.512.

[41] F. Meyer, A. Laaziri,A.M. Papini, J. Uziel, and S. Jugé. A novel phosphorus-carbon bond formation by ring opening with diethyl phosphite of oxazolines derived from serine. Tedrahedron (2004) 60, 3593-3597.

[42] F. Machetti, F.M. Cordero, F. De Sarlo, A.M. Papini, M.C. Alcaro, and A. Brandi. Synthesis of free and N^a-Fmoc/N^a-Boc protected (2S, 4S)- and (2S, 4R)-4-aminopipecolic acids. Eur. J. Org. Chem. (2004) 13, 2928-2935.

[43] A. Innocenti, A. Casini, M.C. Alcaro, A.M. Papini, A. Scozzafava,and C.T. Supuran. Carbonic anhydrase inhibitors: The first on-resin screening of a 4-sulfamoylphenylthioureas library. J. Med. Chem. (2004) 47(21), 5224-5229. DOI: 10.1021/jm049692i.

[44] G. Caminati, E. Peroni, A.M. Papini, and P. Baglioni. Photophysical investigation of lipopeptides of myelin basic protein in phospholipid vesicles. Progress in Colloid & Polymer Science (2004) 126, 163-168. DOI: 10.1007/b93987.

[45] G. Sabatino, M. Chelli, A. Brandi, andA.M. Papini.Analytical methods for solid phase peptide synthesis. Current Organic Chemistry (2004) 8(4),291-301. DOI: 10.2174/1385272043485954

2005

[46] A. Carotenuto, D. D’Addona, E. Rivalta, M. Chelli, A.M. Papini, P. Rovero, and M. Ginanneschi. Synthesis of a dicarba-analogue of octreotide keeping the type II’ b-turn of the pharmacophore in water solution. Lett. Org. Chem. (2005) 2, 274-279.

[47] J. Matsoukas, V. Apostolopoulos, H. Kalbacher, A.M. Papini, T. Tselios, K. Chatzantoni, T. Biagioli, F. Lolli, S. Deraos, P. Papathanassopoulos, A. Troganis, E. Mantzourani, T. Mavromoustakos, and A. Mouzaki. Design and synthesis of a novel potent myelin basic protein epitope 87-99 cyclic analogue: enhanced stability and biological properties of mimics render them a potentially new class of immunomodulators. J. Med. Chem. (2005) 48, 1470-1480.

[48] F. Nuti, S. Hildenbrand, M. Chelli, R. Wodarzb, and A.M. Papini.Synthesis of DEHP metabolites as biomarkers for GC-MS evaluation of phthalates as endocrine disrupters. Bioorg. Med. Chem. (2005) 13, 3461-3465.

[49] A.M. Papini. Simple test for Multiple Sclerosis, Nature Medicine (2005) 11(1), 13.

[50] Lolli F, Mulinacci B, Carotenuto A, Bonetti B, Sabatino G, Mazzanti B, D'Ursi AM, Novellino E, Pazzagli M, Lovato L, Alcaro MC, Peroni E, Pozo-Carrero MC, Nuti F, Battistini L, Borsellino G, Chelli M, Rovero P, Papini AM. An N-glucosylated peptide detecting disease-specific autoantibodies, biomarkers of multiple sclerosis. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10273-8.

[51] F. Lolli, B. Mazzanti, M. Pazzagli, E. Peroni, M.C. Alcaro, R. Lanzillo, V. Brescia Morra, L. Santoro, C. Gasperini, S. Galgani, M.M. D’ Elios, V. Zipoli, S. Sotgiu, M. Pugliatti, P. Rovero, M. Chelli, and A.M. Papini.The glycopeptide CSF114(Glc) detects serum antibodies in Multiple Sclerosis. J. Neuroimmunol. (2005) 167(1-2), 131-137.

[52] S. Giannecchini, M.C. Alcaro, P. Isola, O. Sichi, M. Pistello, A.M. Papini, P. Rovero, and M. Bendinelli. Feline immunodeficiency virus plasma load reduction by a retroinverso octapeptide reproducing the Trp-rich motif of the transmembrane glycoprotein. Antiviral Therapy (2005) 10, 671-680.

[53] F. Lolli, P. Rovero, M. Chelli, and A.M. Papini.Antibodies against glycosylated native MOG are elevated in patients with Multiple Sclerosis. Neurology (2005) 65(5), 781-782.

[54] Kamiński ZJ, Kolesińska B, Kolesińska J, Sabatino G, Chelli M, Rovero P, Błaszczyk M, Główka ML, Papini AM. N-triazinylammonium tetrafluoroborates. A new generation of efficient coupling reagents useful for peptide synthesis. J Am Chem Soc. 2005 Dec 7;127(48):16912-20.

2006

[55] F. Minutolo, S. Bertini, L. Betti, R. Danesi, G. Gervasi, G. Giannaccini, A. Martinelli, A.M. Papini, E. Peroni, G. Placanica, S. Rapposelli, T. Tuccinardi, and M. Macchia. Synthesis of stable snalogues of geranylgeranyl Diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition. Chem. Med. Chem. (2006) 1(2), 218-224.  DOI: 10.1002/cmdc.200500010

[56] A.M. D’Ursi, S. Giannecchini, C. Esposito, M.C. Alcaro, O. Sichi, M.R. Armenante, A. Carotenuto, A.M. Papini, M. Bendinelli, and P. Rovero. Development of antiviral fusion inhibitors: short modified peptides derived from the transmembrane glycoprotein of feline immunodeficiency virus. Chem. Biochem. (2006) 7(5), 774-779. DOI: 10.1002/cbic.200500390

[57] Alcaro MC, Vinci V, D'Ursi AM, Scrima M, Chelli M, Giuliani S, Meini S, Di Giacomo M, Colombo L, Papini AM. Bradykinin antagonists modified with dipeptide mimetic beta-turn inducers. Bioorg Med Chem Lett. 2006 May 1;16(9):2387-90.

[58] M.C. Alcaro, and A.M. Papini. Contribution of peptides to Multiple Sclerosis research. Biopolymers: Peptide Science (2006) 84, 349-367.

[59] V.V. Volkov, F. Nuti, Y. Takaoka, R. Chelli, A.M. Papini, and R. Righini. Hydration and hydrogen bonding of carbonyls in dimyristoyl-phospahtidylcholine bilayer. J. Am. Chem. Soc. (2006) 128, 9466-9471.

[60] A. Carotenuto, A.M. D’Ursi, B. Mulinacci, I. Paolini, F. Lolli, A.M. Papini, E. Novellino, and P. Rovero. Conformation-activity relationship of designed glycopeptides as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis. J. Med. Chem. (2006) 49, 5072-5079.

[61] F. Lolli, P. Rovero, M. Chelli, and A.M. Papini. Toward biomarkers in multiple sclerosis: new advances. Expert Rev. Neurotherapeutics (2006) 6, 781-794.

2007

[62] Rizzolo F, Sabatino G, Chelli M, Rovero P, Papini AM. A convenient microwave-enhanced solid-phase synthesis of difficult peptide sequences: case study of Gramicidin A and CSF114(Glc). Int. J. Pept. Res.Ther. 2007, 13, 1-2, 203-208. doi:10.1007/s10989-006-9066-8

[63] K. Jastrząbek, B. Kolesińska, G. Sabatino, F. Rizzolo, A.M. Papini, and Z.J. Kamiński. Benzyloxy derivatives of triazine-based coupling reagents designed for an efficient solid phase peptide synthesis on polystyrene resin. Int. J. Pept. Res. Ther. (2007) 13, 1-2, 229-236.

[64] B. Kolesińska, J. Frączyk, G. Sabatino, A.M. Papini, and Z.J. Kamiński. Sulfonates of N-triazinylammonium salts as highly efficient, inexpensive and environmentally friendly coupling reagents for peptide synthesis. Chemistry Today (2007) 25(1), 10-13.

[65] I. Paolini, F. Nuti, M.C. Pozo-Carrero, F. Barbetti, B. Kolesinska, Z.J. Kaminski, M. Chelli, and A.M. Papini. A convenient microwave-assisted synthesis of N-glycosyl amino acids. Tetrahedron Letters (2007) 48, 2901-2904.

[66] F. Nuti, I. Paolini, F. Cardona, M. Chelli, F. Lolli, A. Brandi, A. Goti, P. Rovero, and A.M. Papini. Fmoc-protected iminosugar modified asparagine derivatives as building blocks for glycomimetics-containing peptides. Bioorg. Med. Chem. (2007) 15, 3965-3973.

[67] M.C. Alcaro, F. Lolli, P. Migliorini, M. Chelli, P. Rovero, and A.M. Papini. Peptides as autoimmune diseases antigenic probes: a peptide-based reverse approach to detect biomarkers of autoimmune diseases. Chemistry Today (2007) 25(3), 14-16.

[68] V.V. Volkov, R. Chelli, W. Zhuang, F. Nuti, Y. Takaoka, A.M. Papini, S. Mukamel, and R. Righini. Electrostatic interactions in phospholipid membranes revealed by coherent two-dimensional infrared spectroscopy. Proc. Natl. Acad. Sci., U.S.A. (2007) 104, 15323-15327. doi:  10.1073/pnas.0706426104

2008

[69] D'Addona D, Carotenuto A, Novellino E, Piccand V, Reubi JC, Di Cianni A, Gori F, Papini AM, Ginanneschi M. Novel sst5-selective somatostatin dicarba-analogues: synthesis and conformation-affinity relationships. J Med Chem. 2008 Feb 14;51(3):512-20. doi: 10.1021/jm070886i.

[70] F. Real Fernández, A. Chamois-Colson, J. Bayardon, F. Nuti, E. Peroni, R. Meunier-Prest, F. Lolli, M. Chelli, C. Darcel, S. Jugè, and A.M. Papini. Ferrocenyl Glycopeptides as Electrochemical Probes to Detect Autoantibodies in Multiple Sclerosis Patients’ Sera Biopolymers (2008) 90(4), 488-495. DOI: 10.1002/bip.20955

[71] Cantel S, Isaad Ale C, Scrima M, Levy JJ, DiMarchi RD, Rovero P, Halperin JA, D'Ursi AM, Papini AM, Chorev M. Synthesis and conformational analysis of a cyclic peptide obtained via i to i+4 intramolecular side-chain to side-chain azide-alkyne 1,3-dipolar cycloaddition. J Org Chem. 2008 Aug 1;73(15):5663-74. doi: 10.1021/jo800142s. Feautured article and cover.

[72] I. Paolini, F. Rizzolo, and A.M. Papini. Optimized strategies for the synthesis of biomolecules by the microwave approach. Supplement to Chimica Oggi/CHEMISTRY TODAY (2008) 26(3), 16-18.

[73] A. Carotenuto, M.C. Alcaro, M.R. Saviello, E. Peroni, F. Nuti, A.M. Papini, E. Novellino, and P. Rovero. Designed glycopeptides with different b-turn types as synthetic probes for the detection of autoantibodies, biomarkers of Multiple Sclerosis. J. Med. Chem. (2008) 51(17), 5304-5309. DOI: 10.1021/jm800391y.

[74] Le Chevalier Isaad A, Barbetti F, Rovero P, D’Ursi AM, Chelli M, Chorev M, Papini AM.. N(alpha)-Fmoc-Protected omega-Azido and omega-Ynoic-alpha-Amino Acids as Building Blocks for the Synthesis of "Clickable" Peptides. Eur J Org Chem 2008 Nov 31, 5308-5314. DOI: 10.1002/ejoc.200800717

[75] G. Sabatino, and A.M. Papini. Advances in automatic, manual and microwave-assisted solid-phase peptide synthesis Current Opinion in Drug Discovery & Development (2008) 11(6), 762-768.

2009

[76] S. Carganico, P. Rovero, J. A. Halperin, A.M. Papini, and M. Chorev Building Blocks for the Synthesis of Post-Translationally Modified Glycated Peptides and Proteins. J. Pept. Sci. (2009) 15(2), 67-71. DOI: 10.1002/psc.1105.

[77] M.C. Alcaro, I. Paolini, F. Lolli, P. Migliorini, P. Rovero, A.M. Papini. Peptide contribution to the diagnosis of autoimmune diseases. Chimica Oggi/CHEMISTRY TODAY (2009), 27, 2, 11-14.

[78] A.M. Papini Towards peptide-based diagnostics. Chimica Oggi/CHEMISTRY TODAY (2009), 27, 2, 2.

[79] M. Angeles Bonache, F. Nuti, A. Le Chevalier Isaad, F. Real-Fernandez, M. Chelli, P. Rovero, and A.M. Papini. Synthesis of new ribosylated Asn building blocks as useful tools for glycopeptide and glycoprotein synthesis. Tetrahedron Letters (2009) 50, 4151-4153. DOI: 10.1016/j.tetlet.2009.04.124.

[80] A. Le Chevalier-Isaad, A.M. Papini, M. Chorev,andP. Rovero. Side chain-to-side chain cyclization by click reaction. J. Pept. Sci.(2009), 15(7), 451-454.

[81] A.M. Papini. The use of post-translationally modified peptides for detection of biomarkers of immune-mediated diseases. J. Pept. Sci. (2009), 15, 621-628.

[82] M.A Bonache, A. Le Chevalier, F. Nuti, E. Peroni, M. Chelli, P. Rovero, and A.M. Papini. Ribose building block for the synthesis of glycopeptides for fishing out antibodies in autoimmune diseases. Adv. Exp. Med. Biol. (2009) 611:441-2.

2010

[82] Scrima M, Le Chevalier-Isaad A, Rovero P, Papini AM, Chorev M, D'Ursi AM. CuI-Catalyzed Azide–Alkyne Intramolecular i-to-(i+4) Side-Chain-to-Side-Chain Cyclization Promotes the Formation of Helix-Like Secondary Structures. Eur J Org Chem 2010 Jan, 446-457. DOI: 10.1002/ejoc.200901157.

[83] F. Real-Fernández, F. Nuti, M.A. Bonache, M. Boccalini, S. Chimichi, M. Chelli, and A.M. Papini. Microwave-assisted reaction of glycosylamine with aspartic acid. Amino Acids (2010) 39, 599-604. doi: 10.1007/s00726-010-0484-8. Epub 2010 Feb 4.

[84] M. Frediani, D. Sémeril, D. Matt, F. Rizzolo, A.M. Papini, P. Frediani and L. Rosi. Ring Opening Polymerization of rac-Lactide using a calix[4]arene-based Titanium (IV) Complex. International Journal of Polymer Science (2010), 1-6.

[85] M. Frediani, D. Sémeril, D. Matt, F. Rizzolo, A.M. Papini, P. Frediani, L. Rosi, M. Santella, G. Giachi. L-Lactide Polymerization by Calix[4]arene-Titanium (IV) Complex Using Conventional Heating and Microwave Irradiation. e-Polymers (2010) 19, 1-8.

[86] F. Nuti, E. Peroni, F. Real-Fernández, M.A. Bonache, A. Le Chevalier-Isaad, M. Chelli, N. Lubin-Germain, J. Uziel, P. Rovero, F. Lolli, and A.M. Papini. Post-translationally modified peptides efficiently mimicking neo-antigens: a challenge for theragnostics of autoimmune diseases. Biopolymers: Peptide Science (2010) 94, 6, 791-799. DOI: 10.1002/bip.21456

[87] Di Cianni A, Carotenuto A, Brancaccio D, Novellino E, Reubi JC, Beetschen K, Papini AM, Ginanneschi M. Novel octreotide dicarba-analogues with high affinity and different selectivity for somatostatin receptors. J Med Chem. 2010 Aug 26;53(16):6188-97. doi: 10.1021/jm1005868.

[88] A.M. Papini. Cosmetics toward peptide-based cosmeceutics. Chimica Oggi/CHEMISTRY TODAY (2010) 28, 6, 3-4.

2011

[89] F. Gori, B. Mulinacci, L. Massai, C. Avolio, M. Caragnano, E. Peroni, S. Lori, M. Chelli, A.M. Papini, P. Rovero, F. Lolli. IgG and IgM antibodies to the refolded MOG(1-125) extracellular domain in humans. J.Neuroimmunol. (2011) 233, 216-220. ISSN: 0165-5728, DOI: 10.1016/j.jneuroim.2010.11.011

[90] F. Rizzolo, C. Testa, D. Lambardi, M. Chorev, M. Chelli, P. Rovero, A.M. Papini. Conventional and microwave-assisted SPPS approach: a comparative synthesis of PTHrP(1–34)NH₂. J.Pept. Sci. (2011) 17, 708-714. ISSN: 1075-2617, DOI: 10.1002/psc.1395

[91] A.M. Papini. Peptide chemistry revolution. Chimica Oggi/CHEMISTRY TODAY (2011) 29, 5, 29-30. ISSN: 0392-839X

[92] C. Selmi, A.M. Papini, P.Pugliese, M.C. Alcaro, M.E. Gershwin. Environmental pathways to autoimmune diseases: the cases of primary biliary cirrhosis and multiple sclerosis, Archives of Medical Science (2011), 7, 368-380. ISSN: 1734-1922, doi: 10.5114/aoms.2011.23398

2012

[93] C. Testa, F. Nuti, J. Hayek, C. De Felice, M. Chelli, P. Rovero, G. Latini, and A.M. Papini. Di(2-ethylhexyl)phthalate and Autism Spectrum Disorders. ASN NEURO (American Society for Neurochemistry) (2012) 4(4), 223-229 (Open Access http://creativecommons.org/licenses/by-nc/2.5; art:e00089. DOI:10.1042/AN20120015). [3.833]

[94] F. Real-Fernández, I. Passalacqua, E. Peroni, M. Chelli, F. Lolli, A.M. Papini, and P. Rovero. Glycopeptide-based antibody detection in Multiple Sclerosis by surface plasmon resonance. Sensors (2012), 12, 5596-5607; DOI:10.3390/s120505596. ISSN 1424-8220 (Open Access).

[95] Scrima M, Grimaldi M, Di Marino S, Testa C, Rovero P, Papini AM, Chorev M, D'Ursi AM. Solvent independent conformational propensities of [1,2,3]triazolyl-bridged parathyroid hormone-related peptide-derived cyclo-nonapeptide analogues. Biopolymers. 2012;98(6):535-45. doi: 10.1002/bip.22139.

[96] Guardiani C, Signorini GF, Livi R, Papini AM, Procacci P. Conformational landscape of N-glycosylated peptides detecting autoantibodies in multiple sclerosis, revealed by Hamiltonian replica exchange. J Phys Chem B. 2012 May 10;116(18):5458-67. doi: 10.1021/jp301442n.

[97] Pandey, S.; Alcaro, M.C.; Scrima, M.; Peroni, E.; Paolini, I.; Di Marino, S.; Barbetti, F.; Carotenuto, A.; Novellino, E.; Papini, A.M.; D'Ursi, A.M.; and Rovero P. Designed glycopeptides mimetics of myelin protein epitopes as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis. J.Med.Chem. (2012) Dec 13;55(23):10437-47. doi: 10.1021/jm301031r. Epub 2012 Dec 3.

2013

[98] Pandey, S.; Dioni, I.; Lambardi, D.; Real-Fernandez, F.; Peroni, E.; Pacini, G.; Lolli, F.; Seraglia, R.; Papini, A.M. and Rovero P. Alpha actinin is specifically recognized by multiple sclerosis autoantibodies isolated using an N-glucosylated peptide epitope. Mol.Cell.Proteomics. (2013) 12(2), 277-282. DOI: 10.1074/mcp.M112.017087. Epub 2012 Nov 8.

[99] Potenza, M.; Sabatino, G.; Giambi, F.; Rosi, L.; Papini, A.M. and Dei, L. Analysis of egg-based model wall paintings by use of an innovative combined dot-ELISA and UPLC-based approach. Analytical & Bioanalytical Chemistry (2013) 405, 691-701. PRINT ISSN 1618-2642, Online ISSN 1618-265, DOI: 10.1007/s00216-012-6049-9. [IF 3.841].

[100] Chanson J-B., Paolini I., Collongues N., Alcaro M.C., Blanc F., Barbetti F., Fleury M., Peroni E., Rovero P., Rudolf G., Lolli F., Trifilieff E., Papini A.M., de Seze J. Evaluation of new immunological targets in neuromyelitis optica. J. Pept. Sci. (2013) Jan;19(1):25-32. DOI: 10.1002/psc.2470. Epub 2012 Nov 28. PMID: 23193094 [PubMed - indexed for MEDLINE].

[101] Friligou I, Rizzolo F, Nuti F, Tselios T, Evangelidou M, Emmanouil M, Karamita M, Matsoukas J, Chelli M, Rovero P, Papini AM. Divergent and convergent synthesis of polymannosylated dibranched antigenic peptide of the immunodominant epitope MBP(83-99). Bioorg Med Chem. 2013 Nov 1;21(21):6718-25. doi: 10.1016/j.bmc.2013.08.008.

[102] Candelaresi M, Ragnoni E, Cappelli C, Corozzi A, Lima M, Monti S, Mennucci B, Nuti F, Papini AM, Foggi P. Conformational analysis of Gly-Ala-NHMe in D(2)O and DMSO solutions: a two-dimensional infrared spectroscopy study. J Phys Chem B. 2013 Nov 21;117(46):14226-37. doi: 10.1021/jp406139t.

2014

[103] Naegeli A, Neupert C, Fan YY, Lin CW, Poljak K, Papini AM, Schwarz F, Aebi M. Molecular analysis of an alternative N-glycosylation machinery by functional transfer from Actinobacillus pleuropneumoniae to Escherichia coli. J Biol Chem. 2014 Jan 24;289(4):2170-9. doi: 10.1074/jbc.M113.524462.

[104] Pratesi A, Gabbiani C, Michelucci E, Ginanneschi M, Papini AM, Rubbiani R, Ott I, Messori L. Insights on the mechanism of thioredoxin reductase inhibition by Gold N-heterocyclic carbene compounds using the synthetic linear Selenocysteine containing C-terminal peptide hTrxR(488-499): An ESI-MS investigation. J Inorg Biochem. (2014) 136, 161-169. Epub 2014 Jan 21. pii: S0162-0134(14)00013-0. doi: 10.1016/j.jinorgbio.2014.01.009. [Epub ahead of print].

[105] C. Gellini, G. Sabatino, A.M. Papini, M. Muniz-Miranda.SERS study of a tetrapeptide based on histidine and glycine residues, adsorbed on copper/silver colloidal nanoparticles. J. Raman Spectrosc. (2014), 45(6), 418-423. Article first published online: 8 May 2014. doi: 10.1002/jrs.4484

[106] M. Di Pisa, P. Buccato, G. Sabatino, F. Real Fernández, B. Berti, F. Cocola, A.M. Papini, P. Rovero. Epitope Mapping of the N-terminal Portion of Tissue Transglutaminase Protein Antigen to Identify Linear Epitopes in Celiac Disease. J.Pept.Sci. (2014) 20(9), 689-695. Epub 2014 May 15. doi: 10.1002/psc.2650. [Epub ahead of print].

[107] Papini AM, Nuti F, Real-Fernandez F, Rossi G, Tiberi C, Sabatino G, Pandey S, Leoncini S, Signorini C, Pecorelli A, Guerranti R, Lavielle S, Ciccoli L, Rovero P, De Felice C, Hayek J. Immune dysfunction in Rett syndrome patients revealed by high levels of serum anti-N(Glc) IgM antibody fraction. J Immunol Res. 2014;2014:260973. doi: 10.1155/2014/260973.

[108] Auberger N, Di Pisa M, Larregola M, Chassaing G, Peroni E, Lavielle S, Papini AM, Lequin O, Mallet JM. Glaser oxidative coupling on peptides: stabilization of β-turn structure via a 1,3-butadiyne constraint. Bioorg Med Chem. 2014 Dec 15;22(24):6924-32. doi: 10.1016/j.bmc.2014.10.026.

[109] Testa C, Scrima M, Grimaldi M, D'Ursi AM, Dirain ML, Lubin-Germain N, Singh A, Haskell-Luevano C, Chorev M, Rovero P, Papini AM. 1,4-disubstituted-[1,2,3]triazolyl-containing analogues of MT-II: design, synthesis, conformational analysis, and biological activity. J Med Chem. 2014 Nov 26;57(22):9424-34. doi: 10.1021/jm501027w.

2015

[110] Kolesinska B, Rozniakowski KK, Fraczyk J, Relich I, Papini AM, Kaminski ZJ. The Effect of Counter-ion and Tertiary Amine on the Efficiency of N-Triazinylammonium Sulfonates in Solution and Solid-Phase Peptide Synthesis. Eur J O C 2015 Jan; 2, 401-408. doi: 10.1002/ejoc.201402862

[111] Di Pisa M, Pascarella S, Scrima M, Sabatino G, Real-Fernández F, Chelli M, Renzi D, Calabrò A, D'Ursi AM, Papini AM, Rovero P. Synthetic peptides reproducing tissue transglutaminase-gliadin complex neo-epitopes as probes for antibody detection in celiac disease patients' sera. J Med Chem. 2015 Feb 12;58(3):1390-9. doi: 10.1021/jm5017126.

[112] Smerieri A, Testa C, Lazzeroni P, Nuti F, Grossi E, Cesari S, Montanini L, Latini G, Bernasconi S, Papini AM, Street ME. Di-(2-ethylhexyl) phthalate metabolites in urine show age-related changes and associations with adiposity and parameters of insulin sensitivity in childhood. PLoS One. 2015 Feb 23;10(2):e0117831. doi: 10.1371/journal.pone.0117831.

[113] Pratesi A, Ginanneschi M, Melani F, Chinol M, Carollo A, Paganelli G, Lumini M, Bartoli M, Frediani M, Rosi L, Petrucci G, Messori L, Papini AM. Design and solid phase synthesis of new DOTA conjugated (+)-biotin dimers planned to develop molecular weight-tuned avidin oligomers. Org Biomol Chem. 2015 Apr 7;13(13):3988-4001. doi: 10.1039/c4ob02685c.

[114] Rentier C, Monasson O, Nuti F, Rovero P, Sabatino G, Papini AM. Methionine sulfoxide- and sulfone-containing peptide synthesis: management of a relevant post-translational modifications in proteins. Chimica Oggi - Chemistry Today 2015 Mar-Apr Supplement S 33;2:32-35.

[115] Rentier C, Pacini G, Nuti F, Peroni E, Rovero P, Papini AM. Synthesis of diastereomerically pure Lys(Nå-lipoyl) building blocks and their use in Fmoc/tBu solid phase synthesis of lipoyl-containing peptides for diagnosis of primary biliary cirrhosis. J Pept Sci. 2015 May;21(5):408-14. doi: 10.1002/psc.2761.

[116] Real-Fernández F, Rossi G, Lolli F, Papini AM, Rovero P. Label-free method for anti-glucopeptide antibody detection in Multiple Sclerosis. MethodsX. 2015 Mar 12;2:141-4. doi: 10.1016/j.mex.2015.03.004.

[117] Real Fernández F, Di Pisa M, Rossi G, Auberger N, Lequin O, Larregola M, Benchohra A, Mansuy C, Chassaing G, Lolli F, Hayek J, Lavielle S, Rovero P, Mallet JM, Papini AM. Antibody recognition in multiple sclerosis and Rett syndrome using a collection of linear and cyclic N-glucosylated antigenic probes. Biopolymers. 2015 Sep;104(5):560-76. doi: 10.1002/bip.22677.

[118] Papini AM, König E. Novel diagnostic tools and solutions for multiple sclerosis treatment: a patent review (2009-2014). Expert Opin Ther Pat. 2015;25(8):873-84. doi: 10.1517/13543776.2015.1043267. Review.

[119] Bellagha-Chenchah W, Sella C, Real Fernandez F, Peroni E, Lolli F, Amatore C, Thouin L, Papini AM. Interactions between Human Antibodies and Synthetic Conformational Peptide Epitopes: Innovative Approach for Electrochemical Detection of Biomarkers of Multiple Sclerosis at Platinum Electrodes. Electrochimica Acta 2015, Sep 10;176, 1239-1247. doi.org/10.1016/j.electacta.2015.07.158

[120] Pacini G, Carotenuto A, Rentier C, Nuti F, Real-Fernandez F, Brancaccio D, Sabatino G, Larregola M, Peroni E, Migliorini P, Novellino E, Battezzati PM, Selmi C, Papini AM, Rovero P. Role of Lipoylation of the Immunodominant Epitope of Pyruvate Dehydrogenase Complex: Toward a Peptide-Based Diagnostic Assay for Primary Biliary Cirrhosis. J Med Chem. 2015 Aug 27;58(16):6619-29. doi: 10.1021/acs.jmedchem.5b00783.

[121] Real-Fernández F, Cimaz R, Rossi G, Simonini G, Giani T, Pagnini I, Papini AM, Rovero P. Surface plasmon resonance-based methodology for anti-adalimumab antibody identification and kinetic characterization. Anal Bioanal Chem. 2015 Sep;407(24):7477-85. doi: 10.1007/s00216-015-8915-8.

[122] Rentier C, Pacini G, Nuti F, Rovero P, Papini AM. Lipoylated peptides and proteins. In: Top Heterocycl Chem 18 pages. DOI: 10.1007/7081_2015_193 Springer International Publishing Switzerland 2015

[123] Becucci L, Benci S, Nuti F, Real-Fernandez F, Vaezi Z, Stella L, Venanzi M, Rovero P, Papini AM. Interaction Study of Phospholipid Membranes with an N-Glucosylated β-Turn Peptide Structure Detecting Autoantibodies Biomarkers of Multiple Sclerosis. Membranes (Basel). 2015 Sep 30;5(4):576-96. doi: 10.3390/membranes5040576.

[124] Papini AM, Lavielle S, Lubell WD; Co-editors and PIPS organizers. Peptides in Paris. Biopolymers. 2015 Sep;104(5):v-vii. doi: 10.1002/bip.22738.

2016

[125] Walvoort MT, Testa C, Eilam R, Aharoni R, Nuti F, Rossi G, Real-Fernandez F, Lanzillo R, Brescia Morra V, Lolli F, Rovero P, Imperiali B, Papini AM. Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of non-typeable Haemophilus influenzae. Sci Rep. 2016 Dec 23;6:39430. doi: 10.1038/srep39430.

[126] Production of peptides as generic drugs: a patent landscape of octreotide. Sabatino G, Guryanov I, Rombecchi A, Zanon J, Ricci A, Cabri W, Papini AM, Rovero P. Expert Opin Ther Pat. 2016;26(4):485-95. doi: 10.1517/13543776.2016.1158810. Review.

[127] Rett syndrome: An autoimmune disease? De Felice C, Leoncini S, Signorini C, Cortelazzo A, Rovero P, Durand T, Ciccoli L, Papini AM, Hayek J. Autoimmun Rev. 2016 Apr;15(4):411-6. doi: 10.1016/j.autrev.2016.01.011. Review.

[128] Multi-Stage Mass Spectrometry Analysis of Sugar-Conjugated β-Turn Structures to be Used as Probes in Autoimmune Diseases. Giangrande C, Auberger N, Rentier C, Papini AM, Mallet JM, Lavielle S, Vinh J. J Am Soc Mass Spectrom. 2016 Apr;27(4):735-47. doi: 10.1007/s13361-015-1321-9.

[129] Pacini G, Ieronymaki M, Nuti F, Sabatino G, Larregola M, Aharoni R, Papini AM, Rovero P. Epitope mapping of anti-myelin oligodendrocyte glycoprotein (MOG) antibodies in a mouse model of multiple sclerosis: microwave-assisted synthesis of the peptide antigens and ELISA screening. J Pept Sci. 2016 Jan;22(1):52-8. doi: 10.1002/psc.2839.

[130] Pascarella S, Tiberi C, Sabatino G, Nuti F, Papini AM, Giovannelli L, Rovero P. Serpin A1 C-Terminal Peptides as Collagen Turnover Modulators. ChemMedChem. 2016 Aug 19;11(16):1850-5. doi: 10.1002/cmdc.201500472.

2017

[131] Champy AS, Mitaine-Offer AC, Miyamoto T, Tanaka C, Papini AM, Lacaille-Dubois MA. Structural analysis of oleanane-type saponins from the roots of Wisteria frutescens. Magn Reson Chem. 2017 55(6), 595-600. doi: 10.1002/mrc.4550. Epub 2016 Dec 21

[132] Pratesi A, Ginanneschi M, Lumini M, Papini AM, Novellino E, Brancaccio D, Carotenuto A. DOTA-Derivatives of Octreotide Dicarba-Analogs with High Affinity for Somatostatin sst2,5 Receptors. Front Chem. 2017 Feb 23;5:8. doi: 10.3389/fchem.2017.00008. eCollection 2017.

[133] Pratesi A, Stazzoni S, Lumini M, Sabatino G, Carotenuto A, Brancaccio D, Novellino E, Chinol M, Rovero P, Ginanneschi M, Papini AM. Synthesis of dicarba-cyclooctapeptide Somatostatin analogs by conventional and MW-assisted RCM: a study about the impact of the configuration at Cα of selected amino acids. Chemical Engineering & Processing 2017, 122, 365-372. doi.org/10.1016/j.cep.2017.02.005. Available online 22 February 2017.

[134] Ieronymaki M, Nuti F, Brancaccio D, Rossi G, Real-Fernández F, Cao Y, Monasson O, Larregola M, Peroni E, Uziel J, Sabatino G, Novellino E, Carotenuto A, Papini AM, Rovero P. Structure-Activity Relationship Studies, SPR Affinity Characterization, and Conformational Analysis of Peptides That Mimic the HNK-1 Carbohydrate Epitope. ChemMedChem. 2017 May 22;12(10):751-759. doi: 10.1002/cmdc.201700042. Epub 2017 May 3.

[135] Uber, D; Wyrzykowski, D; Tiberi, C; Sabatino, G; Zmudzinska, W; Chmurzynski, L; Papini, AM; Makowska, J. Conformation-dependent affinity of Cu(II) ions peptide complexes derived from the human Pin1 protein ITC and DSC study. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY 2017, 127:2, 1431-1443. DOI: 10.1007/s10973-016-5387-9. Published: FEB 2017

[136] Champy, AS; Mitaine-Offer, AC; Paululat, T; Papini, AM; Lacaille-Dubois, MA. Triterpene Saponins from Wisteria floribunda "macrobotrys" and "rosea". NATURAL PRODUCT COMMUNICATIONS 2017, 12:10, 1573-1576. Published: OCT 2017

2018

[137] Grage SL, Kara S, Bordessa A, Doan V, Rizzolo F, Putzu M, Kubař T, Papini AM, Chaume G, Brigaud T, Afonin S, Ulrich AS. Orthogonal ^¹8F-labeling for solid-state NMR reveals the conformation and orientation of short peptaibols in membranes.Chem.Eur.J. 2018 Jan 11. doi: 10.1002/chem.201704307.

[138] Chiara Testa; Debora D’Addona; Mario Scrima; Anna Maria Tedeschi; Anna Maria D’Ursi; Claire Bernhard; Franck Denat; Claudia Bello; Paolo Rovero; Michael Chorev; Anna Maria Papini. Design, Synthesis and Conformational Studies of [DOTA]-Octreotide Analogues Containing [1,2,3]Triazolyl as a Disulfide Mimetic. PEPTIDE SCIENCE 2018. DOI: 10.1002/pep2.24071

[139] Kukacka Zdenek; Iurascu Marius; Lupu Loredana; Rusche Hendrik; Murphy Mary; Altamore Lorenzo; Borri Fabio; Maeser Stefan; Papini Anna-Maria; Hennermann Julia; Przybylski Michael Antibody Epitope of human α-Galactosidase A revealed by affinity-mass spectrometry: a basis for reversing immunoreactivity in enzyme replacement therapy of Fabry Disease. CHEMMEDCHEM 2018; 13(9); 909-915. DOI:10.1002/cmdc.201800094.

[140] Becucci, Lucia; Aloisi, Giovanni; Papini, Anna Maria; Guidelli, Rolando. Channel-forming activity of nisin in two mercury-supported biomimetic membranes. JOURNAL OF ELECTROANALYTICAL CHEMISTRY 2018; 812; 186-193. DOI:10.1016/j.jelechem.2017.11.06

[141] Champy-Tixier AS, Mitaine-Offer AC, Fernández FR, Miyamoto T, Tanaka C, Papini AM, Lacaille-Dubois MA. Oleanane-type glycosides from the roots of Weigela florida "rumba" and evaluation of their antibody recognition. Fitoterapia. 2018 Apr 30. pii: S0367-326X(18)30258-2. doi: 10.1016/j.fitote.2018.04.017. [Epub ahead of print] PMID: 29723564

[142] Chiara Testa, Anna Maria Papini, Michael Chorev, Paolo Rovero. Copper-catalyzed azide alkyne cycloaddition (CuAAC)-mediated macrocylization of peptides: impact on conformation and biological activity. Curr. Topics Med. Chem 2018 accepted May 5, 2018 Review. DOI: 10.2174/1568026618666180518095755.

[143] Maria Elisabeth Street 1, ID , Sabrina Angelini, Sergio Bernasconi, Ernesto Burgio, Alessandra Cassio, Cecilia Catellani, Francesca Cirillo, Annalisa Deodati, Enrica Fabbrizi, Vassilios Fanos, Giancarlo Gargano, Enzo Grossi, Lorenzo Iughetti, Pietro Lazzeroni, Alberto Mantovani, Lucia Migliore, Paola Palanza, Giancarlo Panzica , Anna Maria Papini, Stefano Parmigiani, Barbara Predieri, Chiara Sartori, Gabriele Tridenti and Sergio Amarri. Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting. Int. J. Mol. Sci. 2018, 19(6), 1647 (44 pages); https://doi.org/10.3390/ijms19061647 (registering DOI) Received: 16 April 2018 / Revised: 23 May 2018 / Accepted: 31 May 2018 / Published: 2 June 2018. Review IF 3.226

[144] Testa C, Papini A.M., Chorev M., Rovero P. Copper-catalyzed Azide-alkyne Cycloaddition (CuAAC)-mediated Macrocyclization of Peptides: Impact on Conformation and Biological Activity. CURRENT TOPICS IN MEDICINAL CHEMISTRY 2018, 18(7), 591-610. Review. DOI: 10.2174/1568026618666180518095755. WOS:000438190700005

Peer-reviewed articles published in books

(Period 1993-2018)

1993-2000

[1] M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani and G. Rapi. Cyclization of histidine azide: A side reaction during peptide synthesis. In: Peptides 1992, C.H. Schneider and A.N. Eberle eds., Escom Science Publishers B.V., Leiden, (1993) pp. 255-256.Pubblicato a Leiden, olanda, 1993. Chem. Abs., 1994, 121, 281171

[2] L. Quartara, G. Balacco, C.A. Maggi, P. Rovero, M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani and G. Rapi. Conformation-activity relationship on MEN 10376 neurokinin A antagonist: Effect of cyclization. In: Peptides 1992, C.H. Schneider and A.N. Eberle eds., Escom Science Publishers B.V., Leiden, The Netherlands, (1993) pp. 591-592. Pubblicato a Leiden, olanda, 1993. Chem. Abs., 1994, 121, 222201.

[3] L. Moroder, K. Köcher, A.M. Papini, M. Dufresne and C.H. Schneider. The mode of Peptide-Antigen Presentation Critically Affects The Specificity of Both Immune Response and Antigen-Antibody Recognition. In: Chemistry of Peptides and Proteins, (1993) Vol. 5/6, part B, D. Brandenburg, V. Ivanov and W. Voelter eds., Verlag Mainz, Aachen, pp. 783-791. Pubblicato a Aachen, Germania, 1993. Chem. Abs., 1994, 121, 298655.

[4] D. Pinzani, A.M. Papini, M.E. Vallecchi, M. Chelli, M. Ginanneschi, C.A. Maggi, R. Patacchini, M. Astolfi, L. Quartara, F.M. Arcamone and G. Rapi. Synthesis and biological activities of glycopeptides of NK2 receptor antagonists. In: Peptides: Chemistry, Structure and Biology P.T.P. Kaumaya and R.S. Hodges eds., Mayflower Scientific Ltd., Kingswindford, U.K. (1996) pp. 649-650. Pubblicato a Kingswindford, West Midlands, gran Bretagna, 1996. Chem. Abs., 1996, 126, 26939.

[5] A.M. Papini, S. Mazzucco, R. Fioresi, E. Nardi, M. Ginanneschi, M. Chelli, S. Matà, F. Lolli, F. Pinto, B. Mazzanti, L. Massacesi and M. Vergelli. [Asn³¹(N-b-d-Glucopyranosyl)]hMOG(30-50): an antigen to identify anti-hMOG peptide antibodies in multiple sclerosis patients. In: Proceedings of the 10^th International Congress of Immunology, New Delhi, India, 1-6 November 1998, Monduzzi Editore, International Proceedings Division Bologna, Italy, Ottobre 1998, pp. 1239-1244. ISBN 88-323-1101-1.

[6] A.M. Papini, S. Mazzucco, E. Nardi, M. Chelli, M. Ginanneschi and G. Rapi. Fmoc-2-aminopalmitic acid for the synthesis of lipopeptides with an hydrophobic chain on a C-C bond. In: Peptides: Frontiers of Peptide Science, James P. Tam andPravin T.P. Kaumaya (Eds.) Kluwer/Escom Academic Publishers, Dordrecht/Boston/London, The Netherlands (1999) pp. 345-346. Chem. Abs., 1999, 131, 200040.

[7] A.M. Papini, S. Mazzucco, D. Pinzani, M. Biondi, M. Chelli, M. Ginanneschi, G. Rapi, B. Mazzanti, M. Vergelli, L. Massacesi and L. Amaducci. Lipoderivatives of an immunodominant epitope of myelin basic protein increased T cell responsiveness in Lewis rats. In: Peptides: Frontiers of Peptide Science, James P. Tam andPravin T.P. Kaumaya (Eds.) Kluwer/Escom Academic Publishers, Dordrecht/Boston/London, The Netherlands (1999) pp. 700-702. Chem. Abs., 1999, 131, 227631

[8] S. Mazzucco, E. Nardi, M. Chelli, M. Ginanneschi, E. Traggiai, M. Vergelli, B. Mazzanti, G. Rapi, L. Massacesi and A.M. Papini. Comparison of the T Cell Proliferative Response to Lipopeptides of the Immunodominant EpitopeshMBP(83-99) and hMBP(141-160). In: Peptides 1998, S. Bajusz and F. Hudecz (Eds.), Akadémiai Kiadò, Budapest (1999) pp. 604-605.Chem. Abs., 2000, 134, 41080

[9] S. Mazzucco, R. Fioresi, S. Matà, M. Vergelli, M. Chelli, F. Lolli, M. Ginanneschi, F. Pinto, B. Mazzanti, L. Massacesi, G. Rapi and A.M. Papini. Glycopeptides of hMOG(30-50) Detect Antibody Response in Multiple Sclerosis and other Neurological Diseases. In: Peptides 1998, S. Bajusz and F. Hudecz (Eds.), Akadémiai Kiadò, Budapest (1999) pp. 46-47. Chem. Abs., 2000, 133, 361706

[10]A.M. Papini, E. Nardi, S. Mazzucco, B. Mazzanti, E. Traggiai, C. Ballerini, H. Kalbacher, H. Beck, M. Chelli, M. Ginanneschi, L. Massacesi and M. Vergelli. Lipophilic modifications of peptide epitopes: T-cell response and susceptibility to peptidases.In: Peptides for the New Millenium G.B. Fields, J.P. Tam and G. Barany, Kluwer/Escom academic publishers, Dordrecht/Boston/London, The Netherlands (2000) pp.697-699. Chem. Abs., 2001, 135, 59864.

[11] E. Nardi,S. Mazzucco, S. Matà, M. Chelli, B. Mazzanti, E. Traggiai, M. Ginanneschi, F. Pinto, L. Massacesi, M. Vergelli, H. Kalbacher, F. Lolli and A.M. Papini. Recombinant MOG from baculovirus inhibits anti-hMOG(30-50) antibodies by the synthetic antigen [Asn³¹(Glc)]hMOG(30-50). In: Peptides for the New Millenium G.B. Fields, J.P. Tam and G. Barany, Kluwer/Escom academic publishers, Dordrecht/Boston/London, The Netherlands (2000) pp. 708-709. Chem. Abs., 2001, 135, 60022.

2001

[12] E. Nardi, M. Chelli, M. Ginanneschi, S. Meini, L. Quartara, M.R. Altamura, C.A. Maggi, F. Formaggio, C. Toniolo, Q.B. Broxterman, P. Rovero, and A.M. Papini. Lipophilic modifications of bradykinin agonists, In: Peptides 2000, J. Martinez ; J.-A. Fehrentz (Eds.), Editions EDK, Paris, France (2001) pp. 929-930. Chem. Abs., 2003, 140, 175310.

[13] J. Uziel, M.C. Alcaro, G. Sabatino, A. Di Fenza, M. Ginanneschi, M. Chelli, P. Rovero, and A.M. Papini.Constrained head-to-tail cyclopeptides by amino acid side chain anchoring to trityl resins. In: Peptides 2000, J. Martinez ; J.-A. Fehrentz (Eds.), Editions EDK, Paris, France (2001) pp. 285-286. Chem. Abs., 2003, 140, 199689

[14] E. Nardi, E. Mastrangelo,S. Matà, B. Mazzanti, V. Zipoli,M. Chelli, M. Ginanneschi, L. Massacesi, M. Vergelli,F. Lolli, F. Pinto,and A.M. Papini.Study of the role of the glycosyl moiety in autoantibody recognition in Multiple Sclerosis. In: Peptides 2000, J. Martinez ; J.-A. Fehrentz (Eds.), Editions EDK, Paris, France (2001) pp. 895-896, Chem. Abs., 2003, 139, 83847.

[15] Carotenuto, A.M. D’Ursi, E. Nardi, E. Mastrangelo, A.M. Papini,and P. Rovero. Conformational studies on a glycopeptide of the human Myelin Oligodendrocyte Glycoprotein. In: Peptides 2000, J. Martinez ; J.-A. Fehrentz (Eds.), Editions EDK, Paris, France (2001) pp. 469-470. Chem. Abs., 2003, 140, 212640.

[16] A.M. Papini,E. Nardi, B. Mazzanti, T. Biagioli, E. Traggiai,M. Chelli, M. Ginanneschi, H. Kalbacher, L. Massacesi, and Marco Vergelli. Effect of lipoconjugation on MBP peptide epitopes for CD4+ T cell responsiveness. In: Peptides 2000, J. Martinez ; J.-A. Fehrentz (Eds.), Editions EDK, Paris, France (2001) pp. 69-70. Chem. Abs., 2003, 140, 161980.

[17] E. Peroni, G. Caminati, P. Baglioni, M. Chelli, and A.M. Papini.A new lipophilic fluorescent probe for interaction studies of bioactive lipopeptides with membrane models. In: Peptides 2000, J. Martinez ; J.-A. Fehrentz (Eds.), Editions EDK, Paris, France (2001) pp. 989-990, Chem. Abs., 2003, 140, 141967.

[18] M.C. Alcaro, A.M. Papini, M. Chelli, D.Fishlock, C. Atkins, and G.A. Lajoie. Stereoselective syntheses of b,g-unsaturated amino acids. In: Peptides 2000, J. Martinez ; J.-A. Fehrentz (Eds.), Editions EDK, Paris, France (2001) pp.359-360, Chem. Abs., 2003, 140, 164146.

2002

[19] A. Carotenuto, A. Di Fenza, E. Nardi, A.M. Papini, and P. Rovero. Conformational studies of a glycopeptide recognized with high affinity by autoantibodies in Multiple Sclerosis. pag. 340-341. In: Peptides. The Wave of the Future. M. Lebl; R.A. Houghten (Eds.), American Peptide Society, San Diego, CA,USA (2001) pp. 340-341, Chem. Abs., 2002, 138, 380990.

[20] M.C. Alcaro, G. Sabatino, M. Ginanneschi, M. Chelli, A. Di Fenza, P. Rovero, and A.M. Papini.A synthetic strategy toward constrained head-to-tail cyclopeptides. In: Peptides 2002, E. Benedetti; C. Pedone (Eds.), Edizioni Ziino, Castellammare di Stabia, Italie (2002) pp. 16-17. Chem. Abs., 2004, 141, 28295.

[21] M.C. Alcaro, T. Terzani, F. Nuti, M. Chelli, F. Machetti, L. Quartara, R. Patacchini, S. Meini, S. Giuliani, A. Brandi, P. Rovero, and A.M. Papini. New constrained amino acids for the study of the role of the basic residues in bradykinin antagonists. In: Peptides 2002, E. Benedetti; C. Pedone (Eds.), Edizioni Ziino, Castellammare di Stabia, Italie (2002) pp. 18-19. Chem. Abs., 2004, 141, 28296.

[22] F. Nuti, S. Cicchi, E. Peroni, M. de la Cruz Pozo-Carrero, B. Mazzanti, M. Pazzagli, F. Lolli,M. Chelli, A.M. Papini, and A. Brandi. Synthesis of new Fmoc-protected iminosugars to study the role of the glycosyl moiety in autoantibody recognition in autoimmune diseases. In: Peptides 2002, E. Benedetti; C. Pedone (Eds.), Edizioni Ziino, Castellammare di Stabia, Italie (2002) pp. 238-239. Chem. Abs., 2004, 141, 52673.

[23] G. Sabatino, B. Mulinacci, M.C. Alcaro, M. Chelli, P. Rovero, andA.M. Papini. A comparative study of coupling reagents for automatic multiple peptide synthesizers. In: Peptides 2002, E. Benedetti; C. Pedone (Eds.), Edizioni Ziino, Castellammare di Stabia, Italie (2002) pp. 272-273. Chem. Abs., 2004, 141, 28422.

[24] B. Mulinacci, E. Peroni, G. Sabatino, B. Mazzanti, M. Pazzagli, M. de la Cruz Pozo-Carrero, M. Chelli, A. Carotenuto, P. Rovero, F. Lolli, and A.M. Papini. Towards rationally designed glycopeptide antigens recognizing autoantibodies in Multiple Sclerosis patients. In: Peptides 2002, E. Benedetti; C. Pedone (Eds.), Edizioni Ziino, Castellammare di Stabia, Italie (2002) pp. 388-389. Chem. Abs., 2004, 141, 37314.

[25] E. Peroni, F. Lolli, B. Mulinacci, F. Nuti, M. Chelli, P. Rovero, and A.M. Papini. Innovative biocompatible immunoadsorbents containing immobilized selective glycopeptide antigens for Multiple Sclerosis therapy, In: Peptides 2002, E. Benedetti; C. Pedone (Eds.), Edizioni Ziino, Castellammare di Stabia, Italie (2002) pp. 584-585. Chem. Abs., 2004, 141, 37453.

[26]A.M. Papini,B. Mulinacci, E. Peroni, G. Sabatino, M. Chelli, A. Carotenuto, P. Rovero, S. Matà, F. Lolli, CSF114(Glc): the glycopeptide detecting autoantibodies in Multiple Sclerosis. PepKit, the first diagnostic test to follow-up the disease activity. In: Peptides 2002, E. Benedetti; C. Pedone (Eds.), Edizioni Ziino, Castellammare di Stabia, Italie (2002) pp. 998-999. Chem. Abs., 2004, 141, 52674.

2004

[27] M.C. Alcaro, P. Campiglia, P. Grieco, E. Novellino, M. Chelli, and A.M. Papini. An efficient microwave-assisted synthesis of 2,5-diketopiperazines libraries. In: Peptide Revolution: Genomics, Proteomics & Therapeutics. M. Chorev & T.K. Sawyer(Eds),American Peptide Society, San Diego, CA, USA (2004)pp. 17-18.

[28] G. Sabatino, M.C. Alcaro, M.C. Pozo-Carrero, M. Chelli, P. Rovero, and A.M. Papini.Assessment of 6Cl-HOBt-based coupling reagents in solid-phase cyclopeptide synthesis. In: Peptide Revolution: Genomics, Proteomics & Therapeutics. M. Chorev & T.K. Sawyer(Eds),American Peptide Society, San Diego, USA (2004)pp. 49-50.

[29] E. Peroni, F. Lolli, B. Mazzanti, M. Pazzagli, B. Bonetti, J. Hoebeke, M. Chelli, P. Rovero, and A.M. Papini.Isolation and characterization of autoantibodies in Multiple Sclerosis patients sera: towards a novel apheresis treatment. In: Peptide Revolution: Genomics, Proteomics & Therapeutics. M. Chorev & T.K. Sawyer(Eds),American Peptide Society, San Diego, CA, USA (2004), pp. 75-76.

[30] F. Nuti, I. Paolini, B. Mulinacci, M.C. Pozo-Carrero, B. Mazzanti, M. Pazzagli, F. Lolli, M. Chelli, F.M. Cordero, A. Brandi, andA.M. Papini. Small focused library of CSF114-type glycopeptides for the characterization of autoantibody recognition in Multiple Sclerosis, In: Peptide Revolution: Genomics, Proteomics & Therapeutics. M. Chorev & T.K. Sawyer(Eds),American Peptide Society, San Diego, CA, USA (2004)pp. 77-78.

[31] A.M. Papini, B. Mulinacci, A. Carotenuto, B. Bonetti, G. Sabatino, E. Peroni, F. Nuti, M.C. Alcaro, M.C. Pozo-Carrero, B. Mazzanti, M. Pazzagli, L. Massacesi, L. Battistini, M. Chelli, P. Rovero, and F. Lolli. MS PepKit: the first diagnostic test to follow-up Multiple Sclerosis. In: Peptide Revolution: Genomics, Proteomics & Therapeutics. M. Chorev & T.K. Sawyer(Eds),American Peptide Society, San Diego, CA, USA (2004)pp.942-944.

[32] B. Mulinacci, F. Nuti, G. Sabatino, M. Chelli, A. Carotenuto, P. Rovero, B. Mazzanti, M. Pazzagli, F. Lolli, and A.M. Papini. Structure-activity relationship study of glycopeptide antigens recognizing specific autoantibodies in Multiple Sclerosis. In: Peptide Revolution: Genomics, Proteomics & Therapeutics. M. Chorev & T.K. Sawyer(Eds),American Peptide Society, San Diego, CA, USA (2004)pp. 1007-1008.

2005

[33] D. D’Addona, M. Chelli, A.M. Papini, A. Carotenuto, F. Budelli, and M. Ginanneschi.Synthesis of a new dicarba-analogue of the drug octreotide^â. In: Peptides 2004. Bridges Between Disciplines. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds),Kenes International, Geneva, Switzerland (2005), pp. 202-203.

[34]B. Kolesinska, G. Sabatino, J. Kolesinska, M. Chelli, P. Rovero, Z. Kaminski, and A.M. Papini. ACP solid phase synthesis by new efficient TBCRs.In: Peptides 2004. Bridges Between Disciplines. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds),Kenes International, Geneva, Switzerland (2005), pp. 232-233.

[35] A.M. Papini, B. Kolesinska, G. Sabatino, J. Kolesinska, and Z. Kaminski. Triazine-based coupling reagents useful tools for SPPS. In: Peptides 2004. Bridges Between Disciplines. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds),Kenes International, Geneva, Switzerland (2005), pp. 252-253.

[36]M. de la Cruz Pozo-Carrero, B. Kolesinska, G. Sabatino, M. Chelli, P. Rovero, Z. Kaminski, and A.M. Papini. An efficient strategy for attachment of Fmoc-amino acids to resins by TBCRs. In: Peptides 2004. Bridges Between Disciplines. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds),Kenes International, Geneva, Switzerland (2005), pp. 257-258.

[37] G. Sabatino, B. Kolesinska, M. Chelli, P. Rovero, Z. Kaminski, and A.M. Papini. Automatic SPPS by the new generation of TBCRs. In: Peptides 2004. Bridges Between Disciplines. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds),Kenes International, Geneva, Switzerland (2005), pp. 263-264.

[38] K. Jastrzabek, B. Kolesinska, M. Blaszczyk, M.L. Glòwka, A.M. Papini, and Z. Kaminski. 2-Chloro-4,6-dibenzyloxy-1,3,5-triazine and N-(4,6-dibenzyloxy-1,3,5-triazinyl-2)ammonium tetrafluoroborates as highly efficient coupling reagents for peptide synthesis in solution.In: Peptides 2004. Bridges Between Disciplines. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds),Kenes International, Geneva, Switzerland (2005), pp. 335-336.

[39] J. Kolesinska, B. Kolesinska, A.M. Papini, and Z. Kaminski. Tetrafluoroborates of N-triazinylammonium salts as highly efficient coupling reagents for peptide synthesis in solution.In: Peptides 2004. Bridges Between Disciplines. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds),Kenes International, Geneva, Switzerland (2005), pp. 337-338.

[40] M.C. Alcaro, E. Naldini, B. Mulinacci, B. Mazzanti, M. Pazzagli, E. Peroni, M. Chelli, P. Rovero, and A.M. Papini. Identification of new autoantigens in Multiple Sclerosis by glycopeptide libraries. In: Peptides 2004. Bridges Between Disciplines. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds),Kenes International, Geneva, Switzerland (2005), pp. 374-375.

[41] B. Mulinacci, I. Paolini, A. Carotenuto, B. Mazzanti, M. Pazzagli, M. Chelli, F. Lolli, P. Rovero, and A.M. Papini. b-Hairpin glycopeptides as mimetic autoantigens in multiple sclerosis. In: Peptides 2004. Bridges Between Disciplines. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds),Kenes International, Geneva, Switzerland (2005), pp. 593-594.

[42] I. Paolini, F. Nuti, B. Kolesinska, F. Cardona, M. Chelli, A. Brandi, and A.M. Papini. New glycosylated building-blocks useful for glycopeptide synthesis. In: Peptides 2004. Bridges Between Disciplines. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds),Kenes International, Geneva, Switzerland (2005), pp. 597-598.

[43] E. Peroni, F. Peri, F. Nuti, M. Chelli, and A.M. Papini. Synthetic strategies for forming the glycan-peptide linkage. In: Peptides 2004. Bridges Between Disciplines. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds),Kenes International, Geneva, Switzerland (2005), pp. 599-600.

2006

[44]I. Paolini, F. Nuti, G. Sabatino, M. Chelli, A.M. Papini. Microwave-assisted synthesis of N-glycosylated building blocks. In: Understanding Biology Using Peptides. S.E. Blondelle (Ed.), American Peptide Society, San Diego, USA (2006), pp. 190-191.

[45]B. Mulinacci, C. Breithaupt, P.P. Pal, N. Budisa, M. Pazzagli, B. Mazzanti, P. Rovero, L. Moroder, A.M. Papini. Cross-reactivity studies of rMOGED with synthetic putative autoantigens CSF114(Glc) and [N³¹(Glc)]hMOG(30-50) in Multiple Sclerosis patients’ sera. In: Understanding Biology Using Peptides. Vol. 9, Part 11, pp. 769-770. (2006). S.E. Blondelle (Ed.), Springer New York, USA. Pubblicato Tuesday, October 23, 2007. ISBN 978-0-387-26569-8 (Print) 978-0-387-26575-9 (Online).

[46]F. Nuti, I. Paolini, E. Peroni, F. Real-Fernandez, M. Pazzagli, M.C. Pozo-Carrero, F. Lolli, M. Chelli, P. Rovero, A.M. Papini. Does an Aberrant Glucosylation Trigger Autoimmunity in Multiple Sclerosis? In: Understanding Biology Using Peptides. Vol. 9, Part 11, pp. 775-776 (2006). S.E. Blondelle (Ed.), Springer New York, USA. Pubblicato October 23, 2007. ISBN 978-0-387-26569-8 (Print) 978-0-387-26575-9 (Online).

[47]M.C. Alcaro, F. Barbetti, F. Nuti, F. Real-Fernandez, B. Mazzanti, M. Chelli, P. Rovero, A.M. Papini. Optimization of Multiple Sclerosis Antigenic Probes by a Combinatorial Approach. In: Understanding Biology Using Peptides Vol. 9, Part 11, pp. 779-780 (2006). S.E. Blondelle (Ed.), Springer New York, USA. Pubblicato October 23, 2007. ISBN 978-0-387-26569-8 (Print) 978-0-387-26575-9 (Online).

[48] E.S. Bulukin, E. Peroni, M. Minunni, M. Pazzagli, P. Rovero, M. Mascini, A.M. Papini. Development of an Efficient Multiple Sclerosis Diagnostic Technology Based on an Optical Glycopeptide Immunosensor. In: Understanding Biology Using Peptides. Vol. 9, Part 11, pp. 785-786. (2006), S.E. Blondelle (Ed.), Springer New York, USA. Pubblicato October 23, 2007. ISBN 978-0-387-26569-8 (Print) 978-0-387-26575-9 (Online).

2007

[49] B. Kolesińska, J. Kolesińska, A. Frymarkiewicz, K.K. Wąsikowska, N. Piątkowska, K. G. Jastrząbek, G. Sabatino, F. Rizzolo, A.M. Papini, Z.J. Kamiński. Synthesis of building blocks for peptide synthesis by using 4-(4,6-dimethoxy-[1,3,5]triazin-2-yl)-4-methyl-morpholinium toluene-4-sulfonate. In: Peptides 2006. K. Rolka, P. Rekowski, J. Silberring (Eds.), Kenes International, Geneva, Switzerland(2007), pp 518-519.

[50] D. D'Addona, F. Gori, A. Di Cianni, F. Bucelli, M. Chelli, A.M. Papini, A. Carotenuto, M. Ginanneschi. A new synthetic approach to unsaturated and saturated dicarba-analogues of octreotide. In: Peptides 2006. K. Rolka, P. Rekowski, J. Silberring (Eds.), Kenes International, Geneva, Switzerland(2007), pp 582-583.

[51] F. Nuti, E. Peroni, E.S. Bulukin, M. Minunni, B. Mulinacci, M. Chelli, M. Mascini, P. Rovero, A.M. Papini. Improvement of autoantibody detection in autoimmune diseases by innovative solid-phase glycopeptide based technologies. In: Peptides 2006. K. Rolka, P. Rekowski, J. Silberring (Eds.), Kenes International, Geneva, Switzerland(2007), pp 588-589.

[52] B. Kolesińska, J. Kolesińska, A. Frymarkiewicz, K.K. Rożniakowski, G. Sabatino, F. Rizzolo, A.M. Papini, Z.J. Kamiński. Sulfonates of N-triazinylammonium salts as highly efficient, inexpensive and environmentally friendly coupling reagents for peptide synthesis in solution. In: Peptides 2006. K. Rolka, P. Rekowski, J. Silberring (Eds.), Kenes International, Geneva, Switzerland(2007), pp 604-605.

[53] B. Kolesińska, S. Grabowski, I. Konieczna, W. Kaca, E. Peroni, A. Papini, P. Rovero Z.J. Kamiński. Immunoenzymatic assay with peptide antigens immobilized on cellulose: effect of the linker on antibody recognition. In: Peptides 2006. K. Rolka, P. Rekowski, J. Silberring (Eds.), Kenes International, Geneva, Switzerland(2007), pp 616-617.

[54] I. Paolini, F. Nuti, E. Peroni, F. Lolli, M. Chelli, P. Rovero, A.M. Papini. An universal peptide scaffold to develop antigenic probes specific for autoimmune diseases.

In: Peptides 2006. K. Rolka, P. Rekowski, J. Silberring (Eds.), Kenes International, Geneva, Switzerland(2007), pp 672-673.

[55] A. Le Chevalier, N. Lubin-Germain, J. Uziel, M. Chelli, F. Lolli, P. Rovero, A.M. Papini. Sugar building-blocks for solid-phase glycopeptides synthesis. In: Peptides 2006. K. Rolka, P. Rekowski, J. Silberring (Eds.), Kenes International, Geneva, Switzerland(2007), pp 680-681

[56] M.C. Alcaro, A. Carotenuto, C. Bonaccini, B. Mulinacci, G. Bonechi, F. Lolli, M. Chelli, P. Gratteri, A. Tramontano, E. Novellino, A.M. Papini, P. Rovero. Conformationally driven rational design of glycopeptides as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis. In: Peptides 2006. K. Rolka, P. Rekowski, J. Silberring (Eds.), Kenes International, Geneva, Switzerland(2007), pp 684-685.

[57] N. Alexandris, M.C. Alcaro, R. Bianchini, A.M. Papini. Design and Synthesis of heme peptides for bioremediation. In: Peptides 2006. K. Rolka, P. Rekowski, J. Silberring (Eds.), Kenes International, Geneva, Switzerland(2007), pp 688-689.

[58] F. Rizzolo, G. Sabatino, I. Paolini, M.C. Alcaro, M.R Moncelli, R. Guidelli, M. Chelli, A.M. Papini, P. Rovero. An efficient microwave-assisted solid phase synthesis of gramicidin a for studies in bilayer-lipid membrane. In: Peptides 2006. K. Rolka, P. Rekowski, J. Silberring (Eds.), Kenes International, Geneva, Switzerland(2007), pp 690-691.

2008

[59] F. Rizzolo, G. Sabatino, M. Fridkin, M. Chelli, P. Rovero, and A.M. Papini. Microwave-assisted solid-phase peptide synthesis: shifting off the limitations affecting conventional synthetic strategies. In Peptides 2008 H. Lankinen, J. Vallivirta, T. Strandin, J. Hepojoki (Eds.) 2008. pp 156-157. ISBN 978-952-92-5198-8.

[60] M.A. Bonache, F. Nuti, A. Le Chevalier Isaad, E. Peroni, M. Chelli, P. Rovero, A.M. Papini. New Building Blocks Useful For The Synthesis Of Ribosylated Peptides. In Peptides 2008 H. Lankinen, J. Vallivirta, T. Strandin, J. Hepojoki (Eds.) 2008. pp 188-189. ISBN 978-952-92-5198-8.

[61] A. Le Chevalier Isaad, M. Scrima, S. Cantel, J. Levy, P. Rovero, A.M. D'Ursi, M. Chorev, A.M. Papini. Synthesis of a Series of Cyclic i-to-i+4 Side Chain-to-Side Chain 1,4-Disubstituted [1,2,3]triazolyl-Bridged PTHrP(11-19) Derivatives.In Peptides 2008 H. Lankinen, J. Vallivirta, T. Strandin, J. Hepojoki (Eds.) 2008. pp 200-201. ISBN 978-952-92-5198-8.

[62] M. Scrima, A. Le Chevalier-Isaad, M. Grimaldi, Paolo Rovero, A.M. Papini, M. Chorev, A.M. D'Ursi. Conformational Preferences of Cyclopeptides Formed by i-to-i+4 Side Chain-to-Side Chain Cyclization via 1,4-Disubstituted [1,2,3]Triazolyl Moiety. In Peptides 2008 H. Lankinen, J. Vallivirta, T. Strandin, J. Hepojoki (Eds.) 2008. pp 266-267. ISBN 978-952-92-5198-8.

[63] A. Di Cianni, D. D’Addona, F. Rizzolo, A.M. Papini, M. Ginanneschi. On-resin microwaves-assisted ring closing metathesis for rapid synthesis of octreotide dicarba-analogues. In Peptides 2008 H. Lankinen, J. Vallivirta, T. Strandin, J. Hepojoki (Eds.) 2008. pp 274-275. ISBN 978-952-92-5198-8.

[64] F. Nuti, N. Qvit, F. Rizzolo, M. Hurevich, E. Peroni, M. Chelli, P. Rovero, C. Gilon, A.M. Papini. Microwave-Assisted Solid Phase Synthesis of Backbone Cyclic Glycopeptide Libraries. In Peptides 2008 H. Lankinen, J. Vallivirta, T. Strandin, J. Hepojoki (Eds.) 2008. pp 278-279. ISBN 978-952-92-5198-8.

[65] A.M. Papini. Peptide-based immunoassays for biomarkers detection: a challenge for translational research. In Peptides 2008 H. Lankinen, J. Vallivirta, T. Strandin, J. Hepojoki (Eds.) 2008. pp 438-439. ISBN 978-952-92-5198-8.

[66] F. Gori, B. Mulinacci, A.M. Papini, P. Rovero, and A.G. Beck-Sickinger. Semi-synthetic approaches to glycosylation of MOG as autoantigen in Multiple Sclerosis disease. In Peptides 2008 H. Lankinen, J. Vallivirta, T. Strandin, J. Hepojoki (Eds.) 2008. pp 444-445. ISBN 978-952-92-5198-8.

[67] E. Innocenti, E. Peroni, F. Nuti, M. Chelli, P. Rovero, C. Selmi and A. M. Papini. Post translational modified peptide-based ELISA to detect autoantibodies in Primary Biliary Cirrhosis. In Peptides 2008 H. Lankinen, J. Vallivirta, T. Strandin, J. Hepojoki (Eds.) 2008. pp 470-471. ISBN 978-952-92-5198-8.

2009

[68] M.C. Alcaro, A. Carotenuto, F. Nuti, I. Paolini, E. Peroni, G. Sabatino, E. Novellino, F. Lolli, A.M. Papini, and P. Rovero. Modified peptides for the diagnosis of autoimmune diseases. New Perspective in Medicinal Chemistry (2009), Vol. 1: 149-158.

[69] E. Peroni, M. Tontini, B. Mulinacci, M. Chelli, F. Lolli, P. Rovero, and A.M. Papini. A Glycopeptide-based Technique for Selective Antibodies Purification. In: Peptides for Youth S. Del Valle, E. Escher, W.D. Lubell (Eds.), Springer (2009), pp. 369-370. ISBN: 978-0-387-73656-3.

[70] M.A. Bonache, A. Le Chevalier, F. Nuti, E. Peroni, M. Chelli, P. Rovero, and A.M. Papini. Ribose Building Block For The Synthesis Of Glycopeptides For Fishing Out Antibodies In Autoimmune Diseases. In: Peptides for Youth S. Del Valle, E. Escher, W.D. Lubell (Eds.), Springer (2009), pp. 441-442. ISBN: 978-0-387-73656-3.

[71] F. Nuti, B. Mulinacci, E. Peroni, M.C. Alcaro, I. Paolini, F. Benedetti, A. Carotenuto, F. Ciolli, F. Lolli, M. Chelli, P. Rovero, and A.M. Papini. Studies for Identification of the Minimal Epitope(s) mimicked by the Synthetic Glucopeptide CSF114(Glc). In: Peptides for Youth S. Del Valle, E. Escher, W.D. Lubell (Eds.), Springer (2009), pp. 431-432.ISBN: 978-0-387-73656-3

[72] F. Gori, B. Mulinacci, E. Bonchi, M. Chelli, F. Lolli, A.M. Papini, and P. Rovero. Semi-Synthetic Strategies to Obtain Glucosylated MOG to Identify Antibodies as Biomarkers in Multiple Sclerosis Disease. In: Peptides for Youth S. Del Valle, E. Escher, W.D. Lubell (Eds.), Springer (2009), pp. 327-328. ISBN: 978-0-387-73656-3.

[73] F. Real-Fernández, A. Chamois-Colson, J. Bayardon, F. Nuti, E. Peroni, M.R. Moncelli, R. Meunier-Prest, S. Jugè, and A.M. Papini. Synthesis Of Organometallic Glycopeptides And Electrochemical Studies To Detect Autoantibodies In Multiple Sclerosis Patients´ Sera. In: Peptides for Youth. S. Del Valle, E. Escher, W.D. Lubell (Eds.), Springer (2009), pp. 435-436. ISBN: 978-0-387-73656-3.

[74] S. Carganico, M.A. Bonache, M.C. Alcaro, M. Chelli, P. Rovero, M. Chorev, A. Lapolla, P. Traldi, and A.M. Papini. Synthetic strategies to Advanced Glycation End products peptides involved in diabetes. In: Peptides for Youth. S. Del Valle, E. Escher, W.D. Lubell (Eds.), Springer (2009), pp.  ISBN: 978-0-387-73656-3.

[75] S. Cantel, J.A. Halperin, M. Chorev, M. Scrima, A.M. D’Ursi, J.J. Levy, R.D. Di Marchi, A. Le Chevalier, P. Rovero, and A.M. Papini. Side chain-to-Side chain Cyclization by Intramolecular Click Reaction - Building Blocks, Solid Phase Synthesis and Conformational Characterization. In: Peptides for Youth. S. Del Valle, E. Escher, W.D. Lubell (Eds.), Springer (2009), pp. 175-176. ISBN: 978-0-387-73656-3.

2010

[76] S. Pandey, E. Peroni, M.C. Alcaro, F. Rizzolo, M. Chelli, P. Rovero, F. Lolli, A.M. Papini. Mimicry Effect of the Neo-Epitope [Asn⁶⁴¹(Glc)]FAN(635-655) with CSF114(Glc) Detecting Autoantibodies in Multiple Sclerosis. In: Peptides 2010. Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). 2010 pp 4-5. ISBN 0-9715560-5-9.

[77] C. Testa, S. Carganico, F. Nuti, M. Scrima, A.M. D’Ursi, M.L. Dirain, N. Lubin Germain, C. Haskell-Luevano, M. Chorev, P. Rovero and A.M. Papini. Stabilization of β Turn Conformation in Melanocortin-Like Peptide by Click Side Chain-To-Side Chain Cyclization. In: Peptides 2010. Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). 2010 pp 14-15. ISBN 0-9715560-5-9.

[78] G. Cane, A. Di Cianni, M. Lumini, AM. Papini, and M. Ginanneschi. An Efficient MW-Assisted Synthesis of Dicarba-Analogues. In: Peptides 2010. Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). 2010 pp 184-185. ISBN 0-9715560-5-9.

[79] F. Rizzolo, F. Nuti, S. Pandey, M. Chelli, P. Rovero, A.M. Papini. Microwave-Assisted Solid Phase Synthesis of [Asn⁶⁴¹(Glc)]FAN(635-655): A New Case Study for Optimisation of Glycopeptide Synthesis. In: Peptides 2010 Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). 2010 pp 186-187. ISBN 0-9715560-5-9.

[80] F. Rizzolo, C. Testa, M. Chorev, M. Chelli, P. Rovero, A.M. Papini. Conventional and Microwave-Assisted SPPS Approach: A Comparative Study of PTHrP(1-34)NH₂ Synthesis. In: Peptides 2010 Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). 2010 pp 188-189. ISBN 0-9715560-5-9.

[81] M. Scrima, A.M. Papini, M. Chorev, A.M. D’Ursi. Molecular Dynamics Calculation and NMR Conformational Studies of Heterodetic Triazolyl Cyclo-Nonapeptides: A Comparative Study. In: Peptides 2010 Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). 2010 pp 220-221. ISBN 0-9715560-5-9.

[82] S. Pandey, D. Lambardi, F. Real-Fernández, M.C. Alcaro, E. Peroni, M. Chelli, A.M. Papini, F. Lolli, P. Rovero. Recognition of Cytoskeletal Proteins Monoclonal IgGs by CSF114(Glc), the Synthetic Probe of Multiple Sclerosis. In: Peptides 2010 Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). 2010 pp 290-291. ISBN 0-9715560-5-9.

[83] M. Di Pisa, G. Sabatino, M. Chelli, P. Rovero, C. Tiberti, A.M. Papini. Celiac Disease: Synthesis of Overlapping Linear Peptide Epitopes of tTG[Aa(1-230)]. In: Peptides 2010 Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). 2010 pp 492-493. ISBN 0-9715560-5-9.

[84] M. Di Pisa, G. Sabatino, M. Chelli, P. Rovero, C. Tiberti, A.M. Papini. Celiac Disease: Characterization of Amino Acids and Short Peptides Finger Print for a Fast I.V.D. In: Peptides 2010 Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). 2010 pp 494-495. ISBN 0-9715560-5-9.

[85] F. Real-Fernández, I. Passalacqua, E. Peroni, F. Lolli, P. Rovero, A.M. Papini. Characterisation of the Minimal Epitope Detecting Autoantibodies in Multiple Sclerosis by Surface Plasmon Resonance. In: Peptides 2010 Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). 2010 pp 498-499. ISBN 0-9715560-5-9.

[86] F. Gori, B. Mulinacci, L. Massai, F. Lolli, A.M. Papini, P. Rovero. Antigenic Probes for Autoantibody Detection in Multiple Sclerosis: Synthetic Peptides versus Recombinant Proteins. In: Peptides 2010 Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). 2010 pp 500-501. ISBN 0-9715560-5-9.

[87] S. Pandey, E. Peroni, P. Rovero, F. Lolli, M. Chelli, A.M. D’Ursi, A.M. Papini. Rational Design and Optimization of the Newly Designed Glycopeptide Sequence to Develop the Diagnostic/Prognostic Assay for Multiple Sclerosis. In: Peptides 2010 Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). 2010 pp 504-505. ISBN 0-9715560-5-9.

2012

[88] F. Nuti, F. Real-Fernandez, G. Rossi, S. Pandey, G. Sabatino, C. Tiberi, M. Larregola, S. Lavielle, J. Hayek, C. De Felice,P. Rovero, A.M. Papini. Autoantibodies to N-glucosylated peptide sequons in Rett syndrome: the first insight to disclose an autoimmune mechanism. In: In: Peptides 2012. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, 2012 pp432-433.ISBN 978-960-466-121-3.

[89] C. Rentier, F. Nuti, M. Chelli, G. Pacini, P. Rovero, C. Selmi, and A. M. Papini. First synthesis of both pure diastereomeric N⁶-(1,2-dithiolane-(3R or S)-pentanoyl)-N²-Fmoc-L-Lys-OH for Fmoc/tBu SPPS. In: Peptides 2012. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, 2012 pp626-627.ISBN 978-960-466-121-3.

[90] C. Rentier, O. Monasson, F. Nuti, P. Traldi, A. Lapolla, M. Larregola, P. Rovero, M. Chorev, and A. M. Papini  Synthesis of glycated and glycosylated peptides to detect autoantibodies in diabetic patients’ sera. In: Peptides 2012. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, 2012 pp186-187. ISBN 978-960-466-121-3.

[91] C. Tiberi, G. Sabatino, M. Di Pisa, G. Rossi, P. Rovero, A. M. Papini  SPPS of N-glucosylated Multivalent Epitopes to detect autoantibodies in Multiple Sclerosis patients’ sera In: Peptides 2012. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, 2012 pp620-621. ISBN 978-960-466-121-3.

[92] G. Sabatino,. M. Di Pisa, F. Potenza, L. Rosi, L. Dei, A.M. Papini Statistical analysis of amino acid fingerprint to characterize protein binders in works of art. In: Peptides 2012. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, 2012 pp644-645. ISBN 978-960-466-121-3.

[93] M. Di Pisa, G. Sabatino, S. M. Chelli, P. Rovero, A. M. Papini Design and synthesis of cross-linked peptide probes for the development of an in vitro diagnostics for Coeliac Disease In: Peptides 2012. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, 2012 pp 630-631.ISBN 978-960-466-121-3

[94] S. Pandey, E. Peroni, I. Dioni, P. Rovero, A. M. Papini From aberrant N-glucosylation to alpha actinin 1 as a new candidate autoantigen of an antibody mediated form of Multiple Sclerosis In: Peptides 2012. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, 2012 pp16-17. ISBN 978-960-466-121-3.

[95] F. Rizzolo, C. Testa, D. Lambardi, M. Chorev, M. Chelli, P. Rovero, A.M. Papini. Fast and efficient microwave-assisted monitoring of difficult peptide sequences. In: Peptides 2012. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, 2012 pp410-411. ISBN 978-960-466-121-3.

[96] O. Monasson, F. Rizzolo, P. Traldi, A. Lapolla, M Chorev, P.Rovero, A.M. Papini Synthesis of the first Multivalent Epitope containing Nε-(1-deoxy-D-fructosyl)lysyl as diagnostic tool for diabetes In: Peptides 2012. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, 2012 pp596-597. ISBN 978-960-466-121-3.

[97] C. Testa, D. D’Addona, M. Scrima,  A. M. D’Ursi, M. L. Dirain, M. Chorev, C. Haskell-Luevano, P. Rovero, A. M. Papini. Synthesis and in vitro activity examinations of 1,4-disubstituted-[1,2,3]triazolyl-containing cyclopeptides, analogs of MT-II, obtained via i to i+5 intramolecular side chain to side chain azide-alkyne cycloaddition.In: Peptides 2012. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, 2012 pp548-549. ISBN 978-960-466-121-3.

2014

[98] C. Rentier, G. Pacini, F. Nuti, E. Peroni, P. Rovero, and A.M. Papini. Synthesis of diastereomeric building-blocks of lipoylated-Lysine and their use in SPPS. In: Peptides 2014. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors) European Peptide Society, 2014 pp45-47. ISBN 978-619-90427-2-4.

[99] D. Petkova, B. Yanachkova, O. Monasson, A.M. Papini, and I. Stoineva. Short Synthetic Peptides as Inhibitors of Angiotensin Converting Enzyme. In: Peptides 2014. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors) European Peptide Society, 2014 pp 59-60. ISBN 978-619-90427-2-4.

[100] C. Rentier, O. Monasson, Z. Ferhat, F. Nuti, M. Larregola , E. Peroni, and A.M. Papini. Methionine oxidation in the tetradecapeptide CSF114(8-21).A case of study. In: Peptides 2014. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors) European Peptide Society, 2014 pp69-70. ISBN 978-619-90427-2-4.

[101] S. Pascarella, F. Melani, L Giovannelli, A.M. Papini, P. Rovero. Molecular modelling assisted design of a TASP mimicking SERPINH1 chaperone function in collagen biosynthesis. In: Peptides 2014. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors) European Peptide Society, 2014 pp152-153. ISBN 978-619-90427-2-4.

[102] S. Pascarella, C. Tiberi, L. Giovannelli, L. Pino, A.M. Papini, P. Rovero. Design, synthesis and biological activity evaluation of peptides as collagen turnover modulators for cosmeceutical purpose. In: Peptides 2014. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors) European Peptide Society, 2014 pp242-243. ISBN 978-619-90427-2-4.

[103] C. Rentier, G. Rossi, F. Nuti, E. Peroni, A. Lapolla, P. Traldi, P. Rovero, and A.M. Papini. Synthesis and evaluation of kynurenine-containing peptides as diagnostic tools for Multiple Sclerosis. In: Peptides 2014. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors) European Peptide Society, 2014 pp262-263. ISBN 978-619-90427-2-4.

[104] G. Rossi, F. Real-Fernández, F. Panza, F. Pratesi, P. Migliorini, A.M. Papini, P. Rovero. SPR-based biosensor analysis of autoantibodies from Rheumatoid Arthritis patients’ sera interacting with citrullinated Multiple Antigen Peptides. In: Peptides 2014. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors) European Peptide Society, 2014 pp266-267. ISBN 978-619-90427-2-4.

[105] F. Real-Fernández,  G. Rossi, F. Niccheri, M. Ramazzotti, D. Degl'Innocenti, F. Lolli, A.M. Papini, P. Rovero. Surface Plasmon Resonance to Select and Characterize Recombinant Human Domain Antibodies. In: Peptides 2014. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors) European Peptide Society, 2014 pp268-269. ISBN 978-619-90427-2-4.

[106] G. Pacini, C. Rentier, F. Nuti, E. Peroni, F. Real Fernàndez, P.M. Battezzati, C. Selmi, P. Rovero, and A.M. Papini. Aberrant post-translational modifications and autoimmunity: the case of Primary Biliary Cirrhosis. In: Peptides 2014. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors) European Peptide Society, 2014 pp 270-271. ISBN 978-619-90427-2-4.

[107] G. Pacini, M. Ieronymaki, M. Larregola, F. Burlina, S. Lavielle, J. Offer, P. Rovero, A.M. Papini. Semi-synthetic strategy to obtain aberrantly N31-glucosylated Myelin Oligodendrocyte Glycoprotein. In: Peptides 2014. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors) European Peptide Society, 2014 pp 290-291. ISBN 978-619-90427-2-4.

[108] V. Doan, G. Chaume, A. Bordessa, F. Rizzolo, E. Peroni, A.M. Papini, S. Kara, S. Afonin, A.S. Ulrich, and T. Brigaud. Solid Phase Peptide Synthesis Of A 19F-Labeled Harzianin: An

Antimicrobal Peptaibol. In: Peptides 2014. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors) European Peptide Society, 2014 pp 362-363. ISBN 978-619-90427-2-4.

Patents

[1] “Glycopeptides, their preparation and use in the diagnosis or therapeutic treatment of Multiple Sclerosis”. Inventors: A.M. Papini,P. Rovero, M. Chelli, F. Lolli. Applicant: University of Florence, Italy. PCT (2003) WO 03000733 A2. Italian Patent n. 0001327122 (27/04/2005). Granted USA, Australian and European Patent (02/08/2005). Licensed to IMMCO Diagnostics, Buffalo, USA.

[2] “Immuno-absorption columns for the subtraction of antibodies from blood with selective plasma filtration techniques”. Inventors: F. Pinto, A.M. Papini, M. Chelli, P. Rovero, F. Lolli. Applicant: University of Florence, Italy. PCT International Application (2003) WO 2003009887 Priority Application: IT 2001-FI144.

[3] “Process for the preparation of N-triazinylammonium salts”. Filing date 07/11/2005. Applicant: Italvelluti S.p.a. Inventors: Z. Kaminski, A.M. Papini, B. Kolesinska, J. Kolesinska, K. Jastrzabek, G. Sabatino, R. Bianchini. PCT/EP2005/055793 (2005).

Kaminski, Zbigniew Jerzy; Papini, Anna Maria; Jastrzabek, Konrad; Kolesinska, Beata; Kolesinska, Justyna; Sabatino, Giuseppina; Bianchini, Roberto. Process for the preparation of n-triazinylammonium salts.    PCT Int. Appl.  (2007),     14pp.  CODEN: PIXXD2  WO  2007051496  A1  20070510  AN 2007:511982    CAPLUS. Licensed to ITALVELLUTI (Italy).

[4] “Somatostatin analogues” Filing date 10.03.2005. Applicant: Giuntini Mauro. Inventors: M. Giuntini, M. Ginanneschi, M. Chelli, A.M. Papini. EPC Application (2005) 05101866.1-2401 Priority Application: IT/10.03.04/ITA FI20040057.

Giuntini, Mauro; Ginanneschi, Mauro; Chelli, Mario; Papini, Anna Maria.  Preparation of somatostatin analogues.    Eur. Pat. Appl.  (2005),     10 pp.  CODEN: EPXXDW  EP  1598366  A1  20051123  CAN 144:7091  AN 2005:1235907    CAPLUS

[5] European patent EP2050761 B1, title “Galactosylated peptides, their preparation and use in autoimmune diseases diagnosis”. Inventors: Alcaro M.C.; Chelli M.; Lolli F.; Migliorini P.; Paolini I.; Papini A.M.; Rovero P.

[6] European patent application EP 2284188 A1 - US 2011028409 A1, title “Detection of anti-ribosomal P protein antibodies by means of synthetic peptides”). Inventors: Pratesi F., Alcaro M.C., Chelli M., Fantini P., Lolli F., Paolini I., Papini A.M., Rovero P., Migliorini P. EP09167004.2 (2009). Patent application number EP10168270.6 - PCT/EP2011/061006 (2010). Non exclusive licenses to Theradiag (France), DIESSE (Italy), DIAMETRA (Italy), Amar Immunodiagnostics (India).

[7]"Method for the diagnosis of rheumatoid arthritis". Inventors: Alcaro M.C.; Pratesi F.; Paolini I.; Chelli M.; Lolli F.; Papini A.M.; Rovero P.; Migliorini P. Applicant Toscana Biomarkers Srl. Patent application number EP11167420.6. (2011). Non exclusive licenses to Theradiag (France), DIESSE (Italy), DIAMETRA (Italy), Amar Immunodiagnostics (India).

[8] European patent application EP2402368 A1 - WO2012001103 A1, title "Histone citrullinated peptides and uses thereof". Inventori: Pratesi F., Alcaro M.C., Chelli M., Lolli F., Paolini I., Papini A.M., Rovero P., Migliorini P. Non exclusive licenses to Theradiag (France), DIESSE (Italy), DIAMETRA (Italy), Amar Immunodiagnostics (India).

[9] F. Denat, D. D’Addona, C. Bernhard, A.M. Papini-Rovero, M. Chorev “Clicked somatostatin conjugated analogs for biological applications”. EP 11193530, 14.12.2011. Déposants: Université de Cergy-Pontoise CNRS and Université de Bourgogne.

[10] J. Hayek, C. De Felice, A.M. Papini, P. Rovero, F. Nuti, F. Real-Fernandez, G. Sabatino, C. Tiberi (2012). Nuovi peptidi glicosilati. Azienda Ospedaliera Universitaria Senese. Licensed to Toscana Biomarkers (Italy).

Invited lectures in Universities and Research Centres, plenary and keynote lectures in International Symposia presented by Anna Maria Papini

(Period 2004-2018)

2004

[IL11] Ciclo de Cursos del Aula “Caja de Burgos” de Estudios Científicos, Avances de la Ciencia y la Tecnología, Burgos, Spagna (Invitata dal Prof. T. Torroba)

February 9-10, 2004, Salòn de Actos de la Faculdad de Ciencias. 3° Curso « The contribution of bioorganic chemitry to the study of autoimmune diseases».

February 9, 2004, h. 16:30: “Lipopeptides of myelin basic protein to study the animal model of multiple sclerosis”

February 10, 2004, h. 16:30: “Glycopeptides for the development of innovative prognostic tests to follow-up multiple sclerosis”.

[IL12] Simposio “Direzioni future nella sclerosi multipla”, Facoltà di Medicina e Chirurgia, Università di Firenze, Dipartimento di Scienze Neurologiche e Psichiatriche, Firenze, Italia (Invitata dal Prof. S. Sorbi) 6 Aprile 2004, h. 9:40, Aula Magna della Facoltà di Medicina. “CSF114(Glc): un glicopeptide sintetico, marker innovativo di sclerosi multipla mediata da autoanticorpi

[IL13] 5th Conference “Medicinal Chemistry: Drug Design and Development”, Conference and Cultural Centre, University of Patras, Greece (Invitata dal Prof. J. Matsoukas) March 11-13, 2004, March 11, L14, h. 15:20. “Development of the innovative designed glycopeptide CSF114(Glc), as prognostic tool for the characterization of an antibody-mediated multiple sclerosis subgroup”

[IL14] 9th Naples Workshop, Peptides as Therapeutic, Diagnostics & Vaccines, Villa Orlandi, Anacapri, Italy (Invitata dal Prof. E. Benedetti) May 8-11, 2004, May 9, h. 11:10. “Peptide-based immunoassays for the diagnosis of autoimmune diseases”

[IL15] Laboratoire de Synthése et Electrosynthése et Organométalliques UMR CNRS 5188 Faculté des Sciences, Dijon, France (Invitata dal Prof. S. Jugé) June 11, 2004,h. 10 :30. “Solid-phase strategy to cyclic structures”

[IL16] D.E.A. Microbiologie-Enzymologie-Nutrition (Aspects Moléculaires et Cellulaires), Magistére Microbiologie-Enzymologie (3éme année). Module Biophysique et Biologie Structurale, Université Henry Poincare, Nancy 1, Faculté des Sciences et Techniques, Nancy, France (Invitata dal Dr. A. Aubry e dal Prof. B. Vitoux) December 3, 2004, h. 14.30-16.30. “Peptides portants des modifications post-traductionnelles pour le diagnostic et la thérapie de pathologies autoimmunes”.

2005

[IL17] Weizmann Institute of Science, Rehovot, Israel (Invitata dal Prof. M. Sela) January 18, 2005. “Glycosylated synthetic probes to detect disease-specific autoantibodies, biomarkers of Multiple Sclerosis”

[IL18] European-Japanese Bioorganic Meeting, Okayama, Japan (Invitata dal Prof. Tetsuo Toraya) March 15-19, 2005. “CSF114(Glc): the first synthetic glycopeptide probe to follow-up disease acrivity in Multiple Sclerosis patients”.

[IL19] Seminaris del Parc Cientific de Barcelona 2005, Universitat de Barcelona, Spagna (Invitata dal Prof. Fernando Albericio), May 19, 2005. “A combinatorial approach for the rational design of innovative prognostic tools for multiple sclerosis”.

[IL20] Laboratoire de Synthése et Electrosynthése et Organométalliques UMR CNRS 5188 Faculté des Sciences, Dijon, France (Invitata dal Prof. C. Moise) May 2, 2005,h. 13.00. « Les bases de la synthése peptidique »

[IL21] Conférences de l’Institut de Chimie des Substances Naturelles, CNRS-UPR2301, Bâtiment 27, Gif-sur-Yvette, Francia (Invitata dal Prof. Jean-Yves Lallemand), 7 Julliet, 2005, h. 11.00. “Les glycopeptides pour le développement de tests prognostiques innovatifs pour suivre la sclérose en plaque: vers un traitement thérapeutique nouveau”.

[IL22] Laboratoire de Synthése et Electrosynthése et Organométalliques UMR CNRS 5188 et Laboratoire d’Ingénierie moléculaire pour la séparation et les applications des Gaz « LIMSAG » (UMR 5633) Université de Bourgogne, Dijon, France (Invitata dal Prof. R. Guilard) 8 Julliet, 2005,h. 10:30. « Bioorganic approach for novel prognostic tests and therapeutic treatment of Multiple Sclerosis”

2006

[IL23] Center for Synthesis and Chemical Biology. Recent Advances in Synthesis and Chemical Biology V. “An Innovative Chemical Reverse Approach to the Discovery of Specific Biomarkers of Autoimmune Diseases” O'Flanagan Theatre, Royal College of Surgeons in Ireland (RCSI) (Invitata dal Prof. Kevin B. Nolan) December 15, 2006, 3.45 p.m. Dublin, Ireland.

2007

[IL24] Israeli-Italian Bi-National Conference Brain functions: from Basic Reasearch to clinical Applications, (invited by Prof. M. Tsodyks). “A chemical reverse approach to biomarker of neurological disordes.” Weizmann Institute of Science, Rehovot, Israel, March 14, 2007, 2:00-2:45 pm.

[IL25] Department of Biological Chemistry, Judea & Samaria College, (invited by Dr. Gary Gellerman). “An aberrant N-glucosylation triggering autoimmunity in Multiple Sclerosis from follow-up of disease activity to specific therapeutic treatments”.Ariel,Israel,March 15, 2007, 11:00 am.

[IL26] The 6^th Congress of the Israeli association for Medicinal Chemistry, Weizmann Institute of Science(invited by Prof. M. Fridkin). “A chemical Reverse Approach to detect biomarkers of autoimmune diseases.” Weizmann Institute of Science, Rehovot, Israel, March 18, 2007, 9:00-9:45 am

[IL27] Department of Chemistry,Bar-Ilan University,(invited by Prof. Gerardo Byk). “Optimized synthetic strategies to glycopeptides for the development of a diagnostic/prognostic test for Multiple Sclerosis.”Ramat-Gan, Israel March 19, 2007, h. 2:00 pm

[IL28]Istituto di Biofisica- Unità Operativa di Pisa. Area Ricerca Pisa- S. Cataldo (invited by Dr. Santi Chillemi). “A chemical reverse approach to decte autoantibodies as biomarkers of autoimmune diseases” May, 2, 2007, 3.00 p.m. Pisa Italy.

[IL29] Modern Solid Phase Peptide Synthesis & its applications. An official satellite meeting of the 7^th international australian peptide symposium (invited by Dr. J. Wade). “N-Triazinylammonium coupling reagents: from the concept of superactive esters to a versatile assistance for peptide synthesis.” Port Douglas, Australia October 18, 2007, 11:00 pm.

[IL30] Howard Florey Institute, University of Melbourne (Invited by Prof. John Wade) “An aberrant N-glucosylation triggering autoimmunity in Multiple Sclerosis: from an efficient follow-up of disease activity to a guide for specific therapeutic treatments” Melbourne, Australia. October 29, 2007.

[IL31] “Peptide Users Group”, Spring Symposium (Invited by Mimotopes). “Optimised synthetic strategies to develop an efficient diagnostic/prognostic test for Multiple Sclerosis” Mimotopes, Melbourne, Australia. October 30, 2007.

[IL32] Burnet Institute, Austin Campus, Heidelberg, Australia (Invited by Prof. V. Apostolopoulos) “Strategies for characterisation of a Multiple Sclerosis pattern disease based on specific autoantibodies as biomarkers” October 31, 2007.

2008

[IL33] Third ERA Chemistry 'Flash' Conference in Killarney, Ireland,.'Carbohydrates at the interfaces of biology, medicine and materials science' ERA-Chemistry Network, the Irish Research Council for Science, Engineering and Technology (IRCSET Ireland) Killarney, Ireland, 9-13 March, 2008 (invited by Prof. S. Oscarson and Prof. P. Murphy) “Aberrant glycosylations as biomarkers of autoimmune diseases correlating with disease activity: toward the development of reliable diagnostic/prognostic tools” March 13, 2008.

[IL34] 6^th Hellenic Forum on Bioactive Peptides, The Conference and Cultural Centre of the University of Patras, Greece, 1st Dimitrios Theodoropoulos Memorial Lecture Award (by Hellenic Peptide Society – Chairman: Prof. P. Cordopatis - e dalla in cooperation with European Peptide Society) A “Chemical Reverse Approach” to modified peptides as synthetic antigenic probes to detect autoantibodies as biomarkers of multiple sclerosis. May 18, 2008.

[IL35] 5th Bulgarian Peptide Symposium 28-30 Maggio 2008 Rila Mountain, Bulgaria (invited by Prof. L. Vezenkov) “Post-translationally modified peptides to develop reliable diagnostic/prognostic assays to follow up autoimmune diseases” May 30, 2008.

[IL36] InvitedProfessor at Département de Chimie de l’Universitè de Cergy-Pontoise, France (invited by Prof. J. Augée and Prof. T. Brigaud) « Conformationally-driven rational design and optimisation of synthetic strategies: a chemical approach to dissect the molecular mechanisms of autoimmune diseases.” April 7, 2008.

[IL37-39] InvitedProfessor at Institut de Chimie Moléculaire de l’Université de Bourgogne, Dijon, France, Société Française de Chimie, Section Bourgogne Franche-Comté, École doctorale Carnot. Salle B401 aile B Bâtiment « Sciences Mirande » (invited by Prof. S. Jugé).

June 13, 2008: Synthesis and Conformational Analysis of a Collection of Clicked PTH Peptides via Intramolecular Side-Chain-to-Side-Chain Cu(I)-Catalyzed Huisgen Reaction

June 16, 2008: N-Triazinylammonium Coupling Reagents:from the Concept of Superactive Esters to a Versatile Assistance for Peptide Synthesis

June 19, 2008: Microwave-Assisted Synthesis: a Challenge for Glycosylated Tools to Dissect the Molecular Mechanisms of Autoimmunity

[IL40] 30th European Peptide Symposium 31 Agosto-5 Settembre  2008, Helsinki, Finland Leonidas Zervas Memorial Lecture Award 2008 (nominated by the European Peptide Society) in commemoration of L. Zervas and the outstanding contributions he made to peptide chemistry “Peptide-based immunoassays for biomarkers detection: a challenge for translational research” 31 Agosto 2008.

[IL41] Istituto Clinico Humanitas Centro di Ricerca e Didattica, Rozzano (Milano, Italy). December 17, 2008. Title: A “Chemical Reverse Approach” to Detect Biomarkers of Autoimmune Diseases: a Challenge for Translational Research

2009

[IL42] Barcelona Biomedical Research Park PRBB-CRG Seminar, Pompeu Fabra University, Barcelona (Spain). February 23, 2009. Title: Peptide-based Immunoassays for  Biomarkers Detection: a Challenge for Translational Research.

[IL43] BioInItaly, Milano (Italy). April 8, 2009. Title: The Start-up Toscana Biomarkers

[IL44] Master di II livello in “Progettazione e Sviluppo di Farmaci” Attualità nella Ricerca Farmaceutica Farmaci peptidici e peptoidici Università degli Studi di Pavia (Italy). April 17, 2009. Title: Recenti progressi nella sintesi di peptidi d’interesse biomedico.

[IL45] BioInItaly, Milano (Italy). May 5, 2009. Title: The Start-up Toscana Biomarkers

[IL46] MAOPS, Microwave Assisted Organic and Peptide Synthesis 2009, La Grande Motte (France). June 4-5, 2009. Title: Optimised strategies for the synthesis of biomolecules: the microwave approach to complex peptides for diagnostics.

[IL47] Conseil Général du Val d’Oise. July 7, 2009. Title: Molecular Detection for Life Sciences (MoDeLS). A project under the Seventh Framework Programme – Regions of Knowledge Initiative

[IL48] 11th International Congress on Amino Acids, Peptides and Proteins, Vienna (Austria). August 3-7, 2009 (Conference August 6, 2009). Title: Glycated and glycosylated amino acids for Solid-Phase GlycoPeptide Synthesis: a challenge to microwave-assisted strategies for R&D diagnostics of autoimmune diseases.

[IL49] Barcelona BioMed Conference – Peptide engineering: Therapeutic peptides. October 26-28, 2009. Title: Click chemistry reaction: a challenge for peptide engineering to develop efficient drugs and diagnostics.

[IL50] Does size matter? Beyond small molecule therapeutics: challenges and success stories”, Université Libre de Bruxelles, Bruxelles (Belgium). November, 6, 2009. Title: Synthetic post-translationally modified peptides for the discovery of new biomarkers of autoimmune diseases: a “Chemical Reverse Approach”.

[IL51] Region of Osaka (Japan) Mission Economique du Val d’Oise. November 10, 2009. Title. Molecular Detection for Life Sciences (MoDeLS): A project under the Seventh Framework Programme – Regions of Knowledge Initiative.

[IL52] Prefectural University of Osaka (Japan). November 12, 2009. Title: Post-translationally modified peptides for detection of biomarkers of immune-mediated diseases: A “Chemical Reverse Approach”.

[IL53] State University of Osaka (Japan). November 13, 2009. Title: Molecular Detection for Life Sciences: An European Project coordinated by the Conseil Général du Val d’Oise.

[IL54] Ricerca Impresa, Polo Scientifico di Sesto Fiorentino, Università di Firenze (Italy). December 3, 2009. Title:Molecular Detection for Life Sciences (MoDeLS): An European Project coordinated by CGVO – Ile de France.

[IL55] Conseil Régional de Bourgogne, Dijon (France). December 9, 2009. Title: Molecular Detection for Life Sciences (MoDeLS): An Innovative Management Model of European Projects

[IL56] TLS Work in Progress, Centro Ricerche Novartis, Siena (Italy). December 11, 2009. Title: Toscana Biomarkers S.r.l. R&D start-up company

[IL57] BioInItaly, Milano (Italy). December 21, 2009. Title: The Start-up Toscana Biomarkers.

2010

[IL58] Presentation to Cosmetic Valley in Neuville Université. February 24, 2010. Title: European Leonardo Institute of Technology@UCP. An Infrastructure to favour Innovation in Cosmetics towards Cosmeceutics.

[IL59] Hybrigenics, Paris (France). March 10, 2010. Title: Post-translationally modified peptides to characterise specific biomarkers of immune-mediated diseases: a challenge for "theragnostics"

[IL60] CGVO Semaine de la Recherche et de l’Innovation Cergy-Pontoise (France).May 3, 2010. Title: Molecular Detection for Life Sciences. An Institute of Technology@UCP. An Infrastructure to favour Innovation in Diagnostics: an European Model

[IL61] XII Convegno-Scuola sulla Chimica dei Carboidrati, Gruppo Interdivisionale Chimica dei Carboidrati della S.C.I. Pontignano (Siena). June 20-23, 2010. Title: Glycated and glycosylated amino acids for Solid-Phase GlycoPeptide Synthesis: a challenge for R&D diagnostics of immune-mediated neurodegenerative diseases.

[IL62] Abant Izzet Baysal University, Faculty of Arts & Sciences Bolu (Turkey). September 20-23, 2010.

Title: 1) Post-translationally modified peptides efficiently mimicking neo-antigens: a challenge for theragnostics of autoimmune diseases.

Title: 2) Click chemistry reaction: a challenge for peptide engineering to develop efficient drugs and diagnostics

[IL63] University of Balikesir (Turkey). September 23-25, 2010. Title: Post-translationally modified peptides for detection of biomarkers of immune-mediated diseases: A “Chemical Reverse Approach”.

[IL64] EU Project Innovation Centre, Chengdu (Sichuan, China). 5th EU-China Business & Technology Cooperation Fair” Biopharmaceutical Forum. October 18, 2010. Title: Molecular Diagnostics for Life Sciences (MoDeLS) An European Infrastructure based on a Technology Platform Network to favour R&D in SMEs

[IL65] Université de Versailles, Saint Quentin en Yvelines (France).November 4, 2010. Title: Chemical approaches to modulate peptide secondary structures inducing specific biological recognition.

[IL66] China – Italy Regional Cooperation Forum on Technology and Innovation, Firenze (Italy). November 11, 2010. Title: Toscana Biomarkers Srl. The proof-of-concept of an innovative approach to molecular diagnostics.

[IL67] Juvenil Diabetes Research Foundation Workshop “Role of Beta Cell Antigen Modifications in the Pathogenesis of T1D and their Diagnostic and Therapeutic Potential”,New York (USA). December 13th, 2010. Title: A “Chemical Reverse Approach” to detect autoantibodies as biomarkers of autoimmune diseases: a challenge for theragnostics.

2011

[IL68] University of Gdansk (Poland). January 17-19, 2011.

Title: 1) Peptide Diagnostics and Therapeutics for Technology Transfer

Title: 2) Chemical approaches to modulate peptide secondary structures inducing specific biological recognition

[IL69] iBiTec-S, CEA/Saclay, Gif sur Yvette (France). January 25, 2011. Title: Post-translationally modified peptides to characterise specific biomarkers of immune-mediated diseases: a challenge for "theragnostics"

[IL70] F. Hoffman La Roche, Basel (Switzerland). February 1, 2011. Title: Toscana Biomarkers S.r.l. R&D start-up company.

[IL71] ICOA - UMR 6005 / Université d'Orléans, Orleans (France). March 30, 2011. Title: Chemical approaches to modulate peptide secondary structures inducing specific biological recognition.

[IL72] Cycle thématique "Dynamiques  des systèmes complexes" : Modélisation de macromolécules biologiques" (Organisateur Pr. R. Livi). St  Martin, Université de Cergy-Pontoise. 31 March, 2011. Title: 3D structures mimicking protein biological activity: from a rational design to peptide-based diagnostics and therapeutics.

[IL73] Attualità nella Ricerca Farmaceutica Farmaci peptidici e peptoidici. Università degli Studi di Pavia, Pavia (Italy). April 15, 2011. Title: “Approcci sintetici per indurre strutture secondarie e modulare l'attività biologica di peptidi. Master 2nd level “Progettazione e Sviluppo di Farmaci”

[IL74] LA NEONATOLOGIA ED OLTRE - NEONATOLOGY AND BEYOND. Sala Universitaria - Palazzo Granafei Nervegna, Brindisi. 14 Maggio 2011. Title: Ricerca di biomarcatori nelle malattie mediate dal sistema immunitario. Corso di aggiornamento

[IL75] Ecole Doctorale, Université de Montpellier (France). May 26, 2011. Title: The importance of a “Chemical Reverse Approach” to modulate peptide secondary structures inducing specific and high affinity biological recognition.

[IL76] Italian-German Meeting: Green and SustainableApproach to Process Intensification, Torino (Italy). 2-3 June 2011. Title: Efficient synthetic strategies aimed to R&D of diagnostics.

[IL77] INSERM U829, Laboratoire SABNP "Structure-Activité des Biomolécules Normales et Pathologiques" Université d'Evry-Val d'Essonne (France). June 7, 2011. Title : A « Chemical Reverse Approach » to develop efficient diagnostic/prognostic assays for immune-mediated diseases.

[IL78] Gordon Research Conference – Carbohydrates Colby College, Waterville, ME. June 21, 2011. Title: The “Chemical Reverse Approach” to develop glycopeptides as synthetic antigens characterising autoantibodies as biomarkers of neurodegenerative diseases.

[IL79] Dipartimento di Scienze della Vita, Università degli Studi di Trieste, Trieste (Italy). July 25, 2011. Title : A « Chemical Reverse Approach » to develop efficient and reliable diagnostics for immune-mediated diseases.

[IL80] Meeting UCP & 3M, Neuville Université. September 1, 2011. Title: Molecular Diagnostics for Life Sciences (MoDeLS). An European Infrastructure based on a Technology Platform Network to favour R&D in SMEs.

2012

[IL81] IPSEN INNOVATION – ZI de Courtaboeuf 5, Av. Du Canada 91940 Les Ulis (France). January 18, 2012. Title: The importance of a “Chemical Reverse Approach” to modulate peptide secondary structures inducing specific and high affinity biological recognition.

[IL82] Gordon Research Conference: Peptides, Chemistry & Biology of Peptides as Signals, BioMaterials and Therapeutics. Ventura Beach Marriott, Ventura, CA (USA) February 19-24, 2012, CA. Chairs: Fred R. Naider & Maria A. Bednarek. February 21, 2012. Discussion Leader: Anna Maria Papini, Session Peptide Vaccines

[IL83] 1^st See-Drug Workshop From chemical to systems biology – Peptide synthesis and protein production May 9-10, 2012, Patras (Greece). May 9, 2012. Title: The importance of a “chemical reverse approach” to modulate secondary structures inducing specific and high affinity biological recognition.

[IL84] Scuola di Dottorato, Aula 1, Edificio E della Presidenza della Facoltà di Scienze dell'Università di Pisa, Via Buonarroti 1, Pisa (Italy). May 28, 2012. Title: Problem solving in diagnostics of immune-mediated diseases: a Chemical Reverse Approach.

[IL85] 13th Naples Workshop on Bioactive Peptides, Aula Magna Partenope, Napoli (Italy). June 7-9, 2012. Title: The mimicry pathway from glycopeptides to specific protein antigens of autoimmune neurodegenerative diseases.

[IL85] Saxon Biotechnology Symposium, BIO CITY LEIPZIG, Centre for Biotechnology and Biomedicine, Deutscher Platz 5, 01403 Leipzig (Germany). June 20th, 2012. Title: Post-translational modified peptides to develop efficient IVD to follow up disease activity of autoimmune diseases: a challenge for theragnostics.

[IL86] 32nd European Peptide Symposium, Athens (Greece). September 2-7 2012 (Conference September 7). Title: The mimicry pathway from anti-glycopeptide antibodies to specific protein antigens of immune-mediated neurodegenerative/neuroregressive diseases: the case study of Rett syndrome.

[IL87] 2nd Austrian Peptide Symposium, Vienna (Austria). November 29 2012. Title: Post-translationally modified peptides detecting autoantibodies as biomarkers of neurodegenerative diseases: A challenge for theragnostics of immune-mediated diseases.

[IL88] Département de Chimie, Faculté des arts et des sciences, Université de Montreal (Québec), Salle 1035, Pavillon J.-A. Bombardier. December 12, 2012 (11h30). Title: A “Chemical Reverse Approach” to Modulate Peptide Secondary Structures Inducing Specific and High Affinity Biological Recognition.

2013

[IL89] Karlsruhe Institute of Technology , Karlsruhe (Germany).January 21, 2013. Title: Peptide secondary structures modulating biological recognition: a “chemical reverse approach”.

[IL90] 22nd Polish Peptide Symposium Kudowa Zdroj (Poland). September 1-5, 2013. Title: Autoimmunity and Neurodegeneration: the Mimicry Pathway From Aberrant N-glucosylated Peptides to Specific Protein Antigens.

[IL91] 4^th Annual EuroPEPTIDES 2013, Clarion Congress Hotel Prague (Czech Republic). November 13-14, 2013. Title: “Optimised Synthetic Strategies to Post-Translationally Modfied Peptides as Reliable Diagnostics of Immune-Mediated Diseases”.

2014

[IL92] 1ère Edition des rencontres interdisciplinaires «Chimie-Biologie». SATT idfinnov, Cité Internationale Universitaire – Maison de Norvège, Paris (France). March 18, 2014. Title : « Projet « PepKit » Mise en place et développement d’une approche de « chimie inverse » à l’Université de Cergy-Pontoise et création de la plateforme PeptLab@UCP ».

[IL93] Hungarian Peptide Symposium, Lake Balaton (Hungary). May 28, 2014. Title: “Post-translationally modified peptides to develop efficient IVDs to follow up disease activity: a challenge for theragnostics of autoimmune diseases”.

[IL94] 14^th Naples Workshop on Bioactive Peptides “The Renaissance era of Peptides in Drug Discovery”, Napoli (Italy), 12-14 June 2014. June 13, 2014. Keynote Lecture Title: “From an N-glucopeptide synthetic probe to an hyper-glucosylated protein antigen: a bacterial infection triggering and antibody mediated form of multiple sclerosis?”.

[IL95] First European Workshop on Tolerogenic Vaccination in Autoimmune Diseases, University of Piemonte Orientale “Amedeo Avogadro” Aula Magna, Via Solaroli 17, 28100 Novara (Italy). November 20, 2014. Title: “Glycopeptides and immune response”.

[IL96] IVScuola di Chimica. CHIMICAMBIENTE – Chimica e prodotti agro-alimentari. Villa Celestina, Pineta Marradi, Castiglioncello (Livorno, Italy).Chema Srl and associazione Chimici della Toscana. November 20-22, 2014. Title: “Amminoacidi, peptidi e proteine negli alimenti”.

2015

[IL97] Conférence Inter-professionnelle SUP’BIOTECH.Dermo-Cosmétologie: les enjeux de la R&D ! Paris (France), February 10, 2015. Title: « Peptides et applications cosmétiques avec la présentation des plateformes de recherche sur les peptides (Université de Cergy-Pontoise) ».

[IL98] Technische Universität München, Emil-Erlenmeyer-Forum 5, Freising-Weihenstephen. Invited by Prof. A. Kaporniotu. June 2, 2015. Title: A “Chemical Reverse Approach” to Modulate Peptide Secondary Structures Inducing Specific and High Affinity Biological Recognition.

IL99] International Joint Israel-Greek-Italian Neuroimmunology Meeting, Elounda, Crete (Greece), June 11-14, 2015. Title: From synthetic glycopeptides to the discovery of bacterial proteins cross-reacting with anti-N-glucosylation antibodies in Multiple Sclerosis.

IL100] COMET 2015, Cergy Pontoise (France), 8 & 9 June 2015, Title : An in vitro technique for biological screening of collagen turnover modulating peptides as anti-aging.

[IL101] 23rd Polish Peptide Symposium August 30 – September 3, 2015. Hotel Zacisze Piłsudskiego 97-215 Spała (Poland). Plenary Lecture September 1, 2015. Title: “Strategies for modulation of secondary structures to optimise biological recognition”.

[IL102] 15th International Conference on Microwave and High Frequency Heating AMPERE 2015, Krakow, Poland, September 14-17, 2015. Keynote Lecture September 16, 2015. Title: The challenge of MW-assisted solid-phase peptide synthesis: R&D of peptide-based diagnostics.

2016

[IL103] Department of Biology, Technische Universität Darmstadt (Germany). Invited by Prof. Maria Cristina Cardoso. July 7, 2016. Title: From an N-glucosylated peptide to a bacterial protein involved in triggering autoantibodies in Multiple Sclerosis and Rett Syndrome

[IL104] BioCIS - Biomolécules: Conception, Isolement, Synthèse, Faculté de Pharmacie, Université Paris-Sud, Chatenay-Malabry (France), October 13, 2016. Invited by Dr. Bruno Figadère. Title: Antibodies from Multiple Sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus Influenzae.

[IL105] Theo Murphy International Scientific Discussion meeting, The Royal Society “Self-assembled peptides: from nanostructure to bioactivity” Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell, Buckinghamshire, MK16 9JJ (UK), October 24-25, 2016. Plenary Lecture October 25, 2016. Title: Autoimmunity and neurodegeneration: the mimicry pathway from aberrant N-glucosylated peptides to specific protein antigens. Tape record of the talk: http://downloads.royalsociety.org/events/2016/10/self-assembled-peptides/Papini.mp3

[IL106] IBB - Istituto CNR di Bostrutture e Bioimmagini, Sezione di Catania (Italy), December 6, 2016. Invited by Dr. Giuseppe Pappalardo. Title: Autoimmunity and neurodegeneration. The mimicry pathway from aberrant N-glucosylated peptides to specific protein antigens, antibodies from Multiple Sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus Influenzae.

2017

[IL107] SECO 54 – 54th Edition of the « Semaine d’Etude en Chimie Organique », May 7-13 2017, Saint Martin de Londres, Hérault (France). Invited by Dr. Kévin Fauché. Title : Peptide and peptidomimetic bioorganic chemistry: the mimicry pathway to contribute to R&D of Diagnostics and Therapeutics understanding the molecular mechanisms of disease conditions.

[IL108] 24th Polish Peptide Symposium on the occasion of the 50th anniversary of the first meeting of Polish scientists working in the field of peptides, Jastrzębia Góra, Gdańsk (Poland), September 3-7, 2017. Invited by Prof. Sylwia Rodziewicz-Motowidło, Chairman of the 24^th Polish Peptide Symposium. Title: Cosmeceuticals behind the secret of youth: a peptide point of view.

2018

[IL109] Technische Universität München, Emil-Erlenmeyer-Forum 5, Freising-Weihenstephen, January 9, 2018. Invited by Prof. Dr. Aphrodite Kapurniotu. Title: Peptides in the pharmaceutical market: state-of-the art and perspectives.

[IL110] Center of Evolutionary Chemical Biology, Department of Chemistry & Nano Science Center, University of Copenhagen, January 11, 2018. Invited by Prof. Dr. Morten Meldal. Title: Antibodies from Multiple Sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus Influenzae.

[IL111] “Endocrine Disrupting Chemicals and Developmental Origins of Health and Disease”, Reggio Emilia, 23 Febbraio 2018. Moderatore della IV session: Nuovi supporti per la ricerca,  invitata dalla Dr. Maria Street.

[IL112] “Peptides and conjugates for tumor targeting, therapy and diagnosis: RiminiPeptides 2018, June 16-18, 2018 Rimini (Italy). Keynote lecture invited by Prof. Dr. Norbert Sewald. Title:Exotic side chain-to-side-chain cyclization modes in octreotide analogs for tumor pretargeting.

[IL113] Euro Chemistry Conference 2018 June 11-13, 2018 Rome, Italy. Keynote lecture Title: Autoimmunity and neurodegeneration: the mimicry pathway from aberrant N-glucosylated peptides to specific bacterial antigens.

[IL114] Wroclaw University of Technology, Zakład Technologii Organicznej i Farmaceutycznej Wydział Chemiczny (Poland), June 28, 2018. Invited by Prof. Dr. Rafal Latajka. Title: "Peptides and conjugates for tumor targeting, therapy and diagnosis: the wonderful world of click chemistry".

[IL115] Symposium “Peptides and conjugates for tumor targeting, therapy and diagnosis: RiminiPeptides2018”, Rimini (Italy), June 16-18, 2018. Invited by Prof. Dr. Norbert Sewald. Invited lecture Title: “Exotic side chain-to-side chain cyclization modes in octreotide analogs for tumor pretargeting”.

[IL116] International Workshop & Summer School “Mass spectrometry in Medical Technology and Biotechnology” Int. MSc Course “Medizintechnik/ Medical Technology”, Rhein Main University, Rüsselsheim am Main (Germany), August 19-25, 2018. Invted by Prof. Dr. Michael Przybylski Plenary opening lecture Title: “A chemical approach to identify peptide epitopes for high affinity antibodies in autoimmune diseases”.

Oral Communications at International Symposia

Underlined the name of the lecturer

2004

[OC21] I. Paolini, F. Nuti, B. Mulinacci, E. Peroni, M.C. Alcaro, G. Sabatino, B. Mazzanti, M. Chelli, A. Brandi, F. Lolli, P. Rovero, and A.M. Papini. Glicopeptidi per la diagnosi e la terapia della sclerosi multipla. Riunione Scientifica Annuale della Società Chimica Italiana Organica, Sezione Toscana, 17 Décembre, 2004.

2005

[OC22] B. Mulinacci, C. Breithaupt, P.P. Pal, N. Budisa, M. Pazzagli, B. Mazzanti, P. Rovero, L. Moroder, and A.M. Papini. Cross-reactivity studies of rMOG_ED with the synthetic putative autoantigen CSF114(Glc) and [N³¹(Glc)]hMOG(30-50) in Multiple Sclerosis patients’ sera. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 Juin, 2005. Bert Schram Price for Young Investigators. LY 03, Abstract p. 484 (presentato dalla Dottoranda B. Mulinacci).

[OC23] A.M. Papini, M.C. Alcaro, E. Peroni, B. Mulinacci, A. Carotenuto, G. Sabatino, B. Mazzanti, M. Pazzagli, M.C. Pozo-Carrero, F. Nuti, L. Battistini, M. Chelli, F. Lolli, and P. Rovero. A combinatorial approach to optimise a prognostic test to follow-up Multiple Sclerosis disease activity. EUROCOMBI3, Winchester, U.K., 18-21 Juillet, 2005, Abstract p. 34.

[OC24] F. Lolli, M. Chelli, P. Rovero, and A.M. Papini. An aberrant N-glucosylation triggering autoimmunity in Multiple Sclerosis. XVIII International Symposium on Glycoconjugates, Glyco XVIII, 4-9 Septembre, 2005, Florence, Italie. L160, Glycoconjugate J., 2005, 22(4–6), 220.

[OC25] B. Kolesinska, Z. Kaminski, and A.M. Papini. New generation of Triazine-based Coupling Reagents. 18th Polish Peptide Symposium, Wroclaw, Pologne, 4-8 Septembre, 2005, Abstract L-18.

[OC26] F. Lolli, M. Chelli, P. Rovero,and A.M. Papini. Role of glycosylation in autoimmune diseases. Mini-Symposium “Multidisciplinary approaches to dissect the molecular mechanisms of diseases”, First European Conference on Chemistry for Life Sciences, Rimini, Italie, 4-8 Octobre, 2005, Lecture, Abstract p. 73.

2006

[OC27] A.M. Papini. An aberrant glucosylation of myelin proteins triggering autoimmunity in Multiple Scleorsis. Chemistry & Biology of Peptides, Gordon Research Conference, February 19-24, 2006 Ventura Beach Marriott, CA, USA.

[OC28] A.M. Papini, A. Carotenuto, M.C. Alcaro, B. Mulinacci, E. Peroni, G. Sabatino, F. Nuti, I. Paolini, M. Chelli, F. Lolli, and P. Rovero. From aberrant post translational modifications of myelin proteins to synthetic antigen probes detecting biomarkers of autoimmune diseases. Promelab, 1^st International Workshop on Expression, Function & Structure of Membrane Proteins. 18-22 June 2006, Firenze, Italy.

[OC29] A.M. Papini, M. C. Alcaro, B. Mulinacci, E. Peroni, G. Sabatino, F. Nuti, I. Paolini, M. Chelli, F. Lolli and P. Rovero. From aberrant post translational modifications of proteins to synthetic antigenic probes detecting biomarkers of autoimmune diseases. 1^st European Chemistry Congress, 27-31 August 2006, Budapest, Hungary (Comunicazione orale presentatata dall’assegnista di ricerca B. Mulinacci).

[OC30] B. Kolesinska, G. Sabatino, M. Chelli, P. Rovero, J. Kolesinska, K.G. Jastrzabek, Z.J. Kaminski, and A.M. Papini. A new generation of N-triazinylammonium coupling reagents versatile for peptide synthesis by different strategies. 29^th European peptide Symposium, Gdansk, Poland, September 3-8, 2006, Abstract L009.

[OC31]G. Sabatino, B. Kolesinska, M. Chelli, J. Kolesinska, P. Rovero, Z. Kaminski, and A.M. Papini. A new generation of N-triazinylammonium coupling reagents versatile for peptide synthesis by different strategies. XXII Congresso Nazionale della Società Chimica Italiana, Firenze, 10-15 Settembre 2006. Abstract ORG-F-17 (Flash Communication presentata dall’assegnista di ricerca G. Sabatino).

[OC32]M.C. Alcaro, A. Carotenuto, A.M. D’Usi, C. Bonaccini, F. Barbetti, F. Lolli, M.Chelli, A. Tramontano, E. Novellino, A.M. Papini, and P. Rovero. Conformationally Driver Rational Design of Glycopeptides as Synthetic Probes for the Detection of Autoantibodies, Biomarkers of Multiple Sclerosis. XXII Congresso Nazionale della Società Chimica Italiana, Firenze, 10-15 Settembre 2006. Abstract GCP-O-06 (Comunicazione orale presentata dall’assegnista di ricerca M.C. Alcaro).

2007

[OC33] A.M. Papini. An innovative “chemical reverse approach” for autoimmune diseases diagnosis: a consistent strategy to include aberrant post-translational modifications. 4th International Peptide Symposium, 7° Australian Peptide Symposium & 2nd Asian Pacific International Peptide Symposium, Cairns, QLA, Australia, October 21-25, 2007. Abstract 26.

2010

[OC34]C. Testa, S. Carganico, F. Nuti, M. Scrima, A. M. D’Ursi, M. L. Dirain, N. Lubin Germain,  C. H. Luevano, M. Chorev,  P. Rovero, A.M. Papini. Stabilization of b-turn conformation in melanocortin like peptide by click side chain-to-side chain cyclization. 31stEuropean Peptide Symposium, 31st EPS, Copenhagen (Denmark), 5-9 September 2010. Oral O8

[OC35] S. Pandey, E. Peroni, MC Alcaro, F. Rizzolo, F. Nuti, M. Chelli, S Matà, P. Rovero, F. Lolli, AM. Papini. Mimicry effect of the neo-epitope [Asn641(Glc)]FAN(635-655) with CSF114(Glc) detecting autoantibodies in Multiple Sclerosis, 31^th European Peptide Symposium, Copenhagen (Denmark), 5-9 September 2010. Abstract O1

2012

[OC36] C. Rentier, and A.M. Papini. Aberrant post-translationally modified peptides for diagnostics and monitoring of autoimmune diseases3rd Ph.D. Day, Florence (Italy), May 16, 2012.

[OC37] C. Rentier, O. Monasson, F. Nuti, E. Peroni, G. Pacini, G. Rossi, M. Larregola, P. Rovero and A.M. Papini. Synthesis of post-translationnally modified peptides as molecular probes for immune-mediated diseases: the case of Primary Biliary Cirrhosis. 18th Congress of GFPP, May 28th, Le Lazaret, Sète (France). Abstract O11, pag. 43.

2014

[OC38] C. Rentier, G. Pacini, F. Nuti, C. Selmi, P.M. Battezzati, P. Rovero and A.M. Papini Peptides of the dihydrolipoyl acetyltransferase for the detection of autoantibodies in autoimmune diseases. 14th Naples Workshop on Bioactive Peptides “The Renaissance Era of Peptides in Drug Discovery”, Naples (Italy), June 12-14 2014.

[OC39] C. Rentier, G. Pacini, F. Nuti, C. Selmi, P.M. Battezzati, P. Rovero and A.M. Papini. PEPTIDES OF THE DIHYDROLIPOAMIDE ACETYLTRNSFERASE FOR THE DETECTION OF AUTOANTIBODIES IN AUTOIMMUNE DISEASES. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Oral. Abstract YO08 – p. 37.

[OC40] M. Larregola, N. Auberger, M. Di Pisa, E. Peroni, G. Chassaing, S. Lavielle, O. Lequin, J.M. Mallet, A.M. Papini. A CONFORMATIONAL STUDY OF NEW GLASER-CYCLIZED PEPTIDES. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Oral. Abstract O45, p 66.

[OC41] S. Pascarella, F. Melani, L. Giovannelli, A.M. Papini, P. Rovero. Mimicking Serine Protease Inhibitor H1 Chaperone Function in Collagen Biosytnhetic Pathway via the Template Assembled Synthetic Protein Approach. Peptides in Paris – PIPS 2014, Gennevilliers site of the University of Cergy-Pontoise, Institute of Advanced Studies. October 5-8, 2014. Abstract YIO10, p. 40.

2015

[OC42] A.M. Papini and M. Larregola. Peptide stability and formulation. Proteinov. Colloque Adebiotech. Biocitech, Cité des entreprises de santé et de Biotechnologies, Romainville (France). 23-24 September 2015.

[OC43] Rentier C, Pacini, G.; A. Carotenuto, Nuti, F.;Selmi,C.; P.M. Battezzati, Rovero, P.; Papini, A.M. Peptides of the dihydrolipoyl acetyltransferase for the detection of autoantibodies in primary biliary cirrhosis. 52^nd Japanese Peptide Symposium, Hiratsuka Japan, November 16-18, 2015 Abstract Y-13 (Best Oral Young Investigator Oral).

2016

[OC44] C. Testa, M.T.C. Walvoort, R. Eilam, R. Aharoni, F. Nuti, G. Rossi, F. Real-Fernandez, R. Lanzillo, V. Brescia Morra, F. Lolli, P. Rovero, B. Imperiali, A.M. Papini. Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus influenza. Cortona Procarioti, Cortona (Italia) 12-14 Maggio 2016. Oral O28.

[OC45] C. Testa, M.T.C. Walvoort, R. Eilam, R. Aharoni, F. Nuti, G. Rossi, F. Real-Fernandez, R. Lanzillo, V. Brescia Morra, F. Lolli, P. Rovero, B. Imperiali, A.M. Papini. Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus influenza. 15^th Naples Workshop on Bioactive Peptides, Napoli (Italia) 23-25 Giugno 2016. Oral O4.

[OC46] C. Testa, M.T.C. Walvoort, R. Eilam, R. Aharoni, F. Nuti, G. Rossi, F. Real-Fernandez, R. Lanzillo, V. Brescia Morra, F. Lolli, P. Rovero, B. Imperiali, A.M. Papini. Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus influenza. 34^th European Peptide Symposium and the 8^th International Peptide Symposium, Leipzig (Germany), 4 – 9 Settembre 2016.

[OC47] L. Altamore, G. Sabatino, F. Real-Fernandez, G. Rossi, A. Lapolla, P. Rovero, A.M. Papini. Peptidi dell'enterovirus Coxsackie: studio della cross-reattività con anticorpi anti-hGAD nel diabete di tipo 1. Prima Giornata Scientifica della Società Italiana Peptidi (ItPS), Napoli (Italia) 22 Giugno 2016. Oral.

2018

[OC48] B. Dalla Volta, G. Sabatino, A. Grammatikopoulos, M. Vignoli, A.M. Papini, G. Pappalardo, P. Rovero, A. Kapurniotu. Conformationally constrained analogues of amyloidogenic segments of Islet Amyloid Polypeptide. II National Conference of Italian Peptide Society, AulaMagna Partenope – Centro Congressi “Federico II”, June 5-6, 2018. O2

[OC49] A. Mazzoleni, C. Testa, S. Francesconi, S. Lavielle, P. Rovero, J.-M. Mallet, and A.M. Papini. Synthesis and characterisation of glucosylated peptides: toward selective plasmapheresis-based treatment of Multiple Sclerosis. II National Conference of Italian Peptide Society, AulaMagna Partenope – Centro Congressi “Federico II”, June 5-6, 2018. O14

[OC50] L. Altamore, C. Testa, F. Real-Fernandez, G. Sabatino, A. Lapolla, C. Selmi, F. Borri, M. Przybylski, J. Hayek, P. Rovero, and A.M. Papini. Use of peptide mimetics of proteins to characterise immune resposne in different pathologies: a powerful approach. II National Conference of Italian Peptide Society, AulaMagna Partenope – Centro Congressi “Federico II”, June 5-6, 2018. O16.

[OC51] C. Bello, A.M. Papini, and C.W. W. Becker. Toward homogeneous glycoproteins via auxiliary-assisted sequential glycosylation and ligation of peptides. 16^th Naples Workshop on Bioactive Peptides, Napoli (Italia) June 7-9, 2018. Oral O27.

[OC52] C. Bello, A.M. Papini, and C.W. W. Becker. Toward homogeneous glycoproteins via auxiliary-assisted sequential glycosylation and ligation of peptides. 35th European Peptide Symposium, University College Dublin (Ireland) August 26-31, 2018. Oral OP7.

Poster presentations at International Symposia

2004

[P74] M. C. Alcaro, E. Naldini, B. Mulinacci, B. Mazzanti, M. Pazzagli, F. Lolli, M. Chelli, P. Rovero, and A.M. Papini. Identification of new autoantigens in Multiple Sclerosis by glycopeptide libraries. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 Septembre, 2004, P125, Abstract p. 153.

[P75] B. Mulinacci, I. Paolini, A. Carotenuto, B. Mazzanti, M. Pazzagli, M. Chelli, F. Lolli, P. Rovero, and A.M. Papini. β-hairpin glycopeptides as mimetic autoantigens in Multiple Sclerosis. 3^rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5-10 Septembre, 2004, P303, Abstract p. 199.

[P76] I. Paolini, F. Nuti, B. Kolesinska, F. Cardona, M. Chelli, B.Mazzanti, F. Lolli, A. Brandi, and A.M. Papini. Optimisation of synthetic strategies to glycosylated amino acids. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 Septembre, 2004, P306, Abstract p. 200.

[P77] E. Peroni, F. Peri, F. Nuti, B. Mazzanti, M. Chelli, and A.M. Papini. An innovative approach to the synthesis of N-glycopeptides. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 Septembre, 2004, P307, Abstract p. 200.

[P78] G. Sabatino, B. Kolesinska, M. Chelli, P. Rovero, Z. J. Kaminski, and A.M. Papini. A comparative study on new not azabenzotriazole-based coupling reagents for SPPS. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 Septembre, 2004, P56, Abstract p. 134.

[P79] M.C. Pozo Carrero, B. Kolesinska, G. Sabatino, M. Chelli, P. Rovero, Z.J. Kaminski, and A.M. Papini. Synthesis of useful building blocks for peptide synthesis: a comparative study of different coupling reagents for ester and amide bonds. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 Septembre, 2004, P51, Abstract p. 133.

[P80] J. Kolesinska, B. Kolesinska, A.M. Papini, and Z.J. Kaminski. N-Triazinylammonnium tetrafluoroborates as new, highly efficient coupling reagents for peptide synthesis in solution. 3rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5-10 Septembre, 2004, P106, Abstract p. 147.

[P81] K. Jastrząbek, M. Błaszczyk, M.L. Główka, B. Kolesinska, A.M. Papini, and Z.J. Kaminski. 2-Chloro-4,6-dibenzyloksy-1,3,5-triazine and N-(3,5-dibenzyloxy-1,3,5-triazinyl-1)ammonium tetrafluoroborates as highly efficient coupling reagents for peptide synthesis in solution. 3rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5-10 Septembre, 2004, P105, Abstract p. 147.

[P82] B. Kolesinska, G. Sabatino, J. Kolesinska, M. Chelli, P. Rovero, Z.J. Kaminskiand, A.M. Papini. New generation of triazine-based coupling reagents useful for SPPS. 3rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5-10 Septembre, 2004, P33, Abstract p. 129.

[P83] A.M. Papini, B. Kolesinska, G. Sabatino, J. Kolesinska, Z.J. Kaminski. Selection of the best triazine-based condensing reagent for SPPS. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 Septembre, 2004, P49, Abstract p. 133.

[P84] B. Mazzanti, M. Pazzagli, M.C. Alcaro, B. Mulinacci, E. Peroni, F. Nuti, G. Sabatino, M.C. Pozo-Carrero, A. Carotenuto, B. Bonetti, L. Battistini, D. Franciotta, S. Sotgiu, R. Lanzillo, M. Chelli, P. Rovero, F. Lolli, and A.M. Papini. A proteomic approach to characterize a native antigen involved in autoantibody response in Multiple Sclerosis by a structure-based designed glycopeptide. Seventh International Congress of the International Society of Neuroimmunology, Venise (Italie) 28 Septembre-2 Octobre, 2004, Abstract 313 in: J. Neuroimmunol. (2004) 154, 95.

2005

[P85] M.C. Alcaro, P. Rovero, and A.M. Papini. Fishing for antigens recognizing autoantibodies in Multiple Sclerosis. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 Juin, 2005, PY 20, Abstracts p. 507.

[P86] E. Bulukin, E. Peroni, M. Minunni, M. Pazzagli, P. Rovero, M. Mascini, and A.M. Papini. Development of an efficient Multiple Sclerosis diagnostic technique based on an optical glycopeptide immunosensor. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 Juin, 2005.

[P87] E. Peroni, M.C. Alcaro, F Barbetti, F. Nuti, F. Real-Fernàndez, B. Mazzanti, M.Chelli, P. Rovero, and A.M. Papini. Combinatorial approach to develop the optimal glycopeptide as molecular probe to characterize autoantibodies in Multiple Sclerosis. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 Juin, 2005, PY 46, Abstracts p. 512.

[P88] F.Nuti, I. Paolini, B.Mazzanti, F. Real-Fernàndez, M.C. Pozo-Carrero, M. Chelli, P.Rovero, and A.M. Papini. Asparaginyl glucose is fundamental for autoantibody recognition in Multiple Sclerosis. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 Juin, 2005, PY 17, Abstracts p. 507.

[P89] G. Sabatino, I. Paolini, M.C. Pozo-Carrero, M. Chelli, P. Rovero, and A.M. Papini. Optimized conditions for glycopeptide synthesis by a microwave peptide synthesizer. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 Juin, 2005, PY 16, Abstracts p. 507.

[P90] I. Paolini, F. Nuti, I. Matteini, G. Sabatino, M. Chelli, and A.M. Papini. Microwave-assisted synthesis of glycosylated building blocks. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 Juin, 2005, PY 15, Abstracts p. 507.

[P91] E. Peroni, E. Bulukin, M. Minunni, M. Pazzagli, P. Rovero, M. Mascini, and A.M. Papini. Development of a high-throughput screening for Multiple Sclerosis patients’ sera based on an optical glycopeptide immunosensor. EUROCOMBI-3 conference, Winchester, U.K. 18-21 Juin, 2005. Abstract p. 98

[P92] K. Jastrzabek, B. Kolesinska, A.M. Papini, G. Sabatino, and Z. Kaminski. 2-Chloro-4,6-dibenzyloxy-1,3,5-triazine and its quaternary N-1,3,5-triazinylammonium salts. Highly efficient coupling reagents of new generation with modified substituents in triazine ring. 18th Polish Peptide Symposium, Wroclaw, Pologne, 4-8 Septembre, 2005, Abstract P-33W.

[P93] F. Nuti, I. Paolini, B.Mulinacci, M. Pazzagli, F. Lolli, M. Chelli, P. Rovero, and A.M. Papini. Sugar-scan of CSF114(Glc) for autoantibody recognition in Multiple Sclerosis. XVIII International Symposium on Glycoconjugates. Glyco XVIII”, Florence (Italie), 4-9 Septembre, 2005, Abstract P057, Glycoconjugate J., 2005, 22(4–6), 254. Best Poster Award.

[P94] F. Rizzolo, B. Mulinacci, F. Nuti, M. Pazzagli, M. Chelli, F. Lolli, P. Rovero, and A.M. Papini. Synthesis of glucosylated peptides: role of the amino acid sequence in autoantibody recognition in Multiple Sclerosis patients’ sera. XVIII International Symposium on Glycoconjugates. Glyco XVIII”, Florence (Italie), 4-9 Septembre, 2005, Abstract P063, Glycoconjugate J., 2005, 22(4–6), 257.

[P95] B. Mulinacci, C. Breithaupt, N. Budisa, P. Rovero, L. Moroder, and A.M. Papini. Cross-reactivity studies of rMOG_ED with the synthetic putative autoantigen CSF114(Glc) in Multiple Sclerosis patients’ sera. XVIII International Symposium on Glycoconjugates. Glyco XVIII”, Florence (Italie), 4-9 Septembre, 2005, Abstract P262, Glycoconjugate J., 2005, 22(4–6), 337.

[P96] A. Le Chevalier,M. Ousmer, N. Lubin-Germain,J. Uziel, E. Peroni, M. Chelli, F. Lolli, P. Rovero, and A.M. Papini. Role of glucose bonding to amino acids in myelin proteins for autoantibody recognition in Multiple Sclerosis. XVIII International Symposium on Glycoconjugates. Glyco XVIII”, Florence (Italie), 4-9 Septembre, 2005, Abstract P051, Glycoconjugate J., 2005, 22(4–6), 252.

[P97] G. Fontanive, I. Adamo, F. Berti, F. Benedetti, I. Paolini, and A.M. Papini. Stereoselective synthesis of pseudopeptides containing the minimal epitope fundamental for antibody recognition in Multiple Sclerosis. 1st European Conference on Chemistry for Life Sciences, Rimini (Italie), 4-8 Octobre, 2005, Poster, Abstract p. 97.

[P98] M. Ginanneschi, D. D’Addona, F. Gori, M. Chelli, A.M. Papini, and F. Bucelli. Synthesis of new octreotide dicarba-analogues. 1st European Conference on Chemistry for Life Sciences, Rimini (Italie), 4-8 Octobre, 2005, Poster, Abstract p. 115.

[P99] M. de la Cruz Pozo-Carrero, F. Nuti, I. Paolini, G. Sabatino, M. Pazzagli, M. Chelli, F. Lolli, P. Rovero, and A.M. Papini. An aberrant N-glucosylation triggering autoimmunity in Multiple Sclerosis. 1st European Conference on Chemistry for Life Sciences, Rimini (Italie), 4-8 Octobre, 2005, Poster, Abstract p. 157.

[P100] G. Sabatino, Z.J. Kamiński, B. Kolesińska, J. Kolesińska, M. Pozo-Carrero, M. Chelli, P. Rovero, and A.M. Papini. New generation of a Triazine-Based coupling reagent useful for a large scale solid-phase synthesis of a specific Multiple Sclerosis antigenic probe. 1st European Conference on Chemistry for Life Sciences, Rimini (Italie), 4-8 Octobre, 2005, Poster, Abstract p. 161.

2006

[P101] M.C. Alcaro, B. Mulinacci, G. Bonechi, F. Barbetti, I. Paolini, E. Peroni, F. Nuti, G. Sabatino, M. Chelli, C. Bonaccini, A. Tramontano, F. Lolli, A. Carotenuto, P. Rovero, and A. M. Papini. Looking for native antigens triggering an autoantibody response in Multiple Sclerosis. Chemistry & Biology of Peptides, Gordon Research Conference, February 19-24, 2006 Ventura Beach Marriott, CA, USA.

[P102] E. Peroni, I. Paolini, F. Nuti, B. Mulinacci, G. Sabatino, M. C. Alcaro, E. S. Bulukin, F. Lolli, M. Chelli, P. Rovero, and A. M. Papini.A universal peptide scaffold to develop antigenic probes specific for autoimmune diseases. Chemistry & Biology of Peptides, Gordon Research Conference, February 19-24, 2006 Ventura Beach Marriott, CA, USA.

[P103] B. Mulinacci, C. Breithaupt, P.P. Pal, N. Budisa, M. Pazzagli, B. Mazzanti, P. Rovero, L. Moroder, and A.M. Papini. Cross-reactivity studies of rMOG_ED with the synthetic putative autoantigen CSF114(Glc) and [N³¹(Glc)]hMOG(30-50) in Multiple Sclerosis patients’ sera. Promelab, 1^st International Workshop on Expression, Function & Structure of Membrane Proteins. June 18-22, 2006, Firenze, Italy.

[P104]C. Tommasi, M.C. Alcaro, C. Anzilotti, D. Chimenti, F. Pratesi, M. Rosati, A.M. Papini, P. Rovero, P. Migliorini.Synovial Antigens Target of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis.1^st Congress of the Italian Proteomic Association (ItPA), Pisa (Italy), July 2-4, 2006, Abstract H47.

[P105]B. Kolesinska, S. Grabowski, W. Kaca, E.Peroni, A.M. Papini, P. Rovero, and Z.J. Kaminski. Immunoenzymatic assay with peptide antigens immobilised on cellulose: effect of the linker on antibody recognition. 29^th European Peptide Symposium, Gdansk, Poland, September 3-8, 2006, Abstract Th480.

[P106] A. Carotenuto, M.C. Alcaro, C. Bonaccini, F. Barbetti, F. Lolli, M. Chelli, A. Tramontano, E. Novellino, A.M. Papini, and P. Rovero. Conformationally driven rational design of glycopeptides as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis. 29^th European Peptide Symposium, Gdansk, Poland, September 3-8, 2006, Abstract Tu494.

[P107]F. Nuti, E. Peroni, E.S. Bulukin, B. Mulinacci, M. Chelli, P. Rovero, and A.M. Papini. Improvement of autoantibody detection in autoimmune diseases by innovative solid-phase glycopeptide based technologies. 29^th European Peptide Symposium, Gdansk, Poland, September 3-8, 2006, Abstract M541.

[P108] A. Le Chevalier, N. Lubin-Germain, J. Uziel, M. Chelli, F. Lolli, P. Rovero, and A. M. Papini.Sugar building blocks for solid-phase glycopeptides synthesis. 29^th European Peptide Symposium, Gdansk, Poland, September 3-8, 2006, Abstract M028.

[P109] I. Paolini, F. Nuti, E. Peroni, F. Lolli, M. Chelli, P. Rovero, and A. M. Papini.An universal peptide scaffold to develop antigenic probes specific for autoimmune diseases. 29^th European Peptide Symposium, Gdansk, Poland, September 3-8, 2006, Abstract Th504.

[P110] M.C. Alcaro, B. Mulinacci, G. Bonechi, F. Barbetti, I. Paolini, E. Peroni, F. Nuti, G. Sabatino, M. Chelli, C. Bonaccini, A. Tramontano, F. Lolli, A. Carotenuto, P. Rovero, and A. M. Papini. Looking for native antigens triggering an autoantibody response in Multiple Sclerosis.29^th European Peptide Symposium, Gdansk, Poland, September 3-8, 2006, Abstract .

[P111] D. D’Addona, F. Gori, A. Di Cianni, F. Bucelli, A. Carotenuto, M. Chelli, A. M. Papini, and M. Ginanneschi. A new synthetic approach to saturated and unsaturated dicarba-analogues of octeotride. 29^th European Peptide Symposium, Gdansk, Poland, September 3-8, 2006, Abstract Th081.

[P112] F. Rizzolo, G. Sabatino, I. Paolini, M.C. Alcaro, M.R. Moncelli, R. Guidelli, M. Chelli, and A.M. Papini, P.Rovero. An efficient microwave-assisted soli-phase synthesis of Gramicidin A for studies in bilayer lipid membrane. 29^th European Peptide Symposium, Gdansk, Poland, September 3-8, 2006, Abstract Th107.

[P113] Nikos Alexandris, Maria Claudia Alcaro, Roberto Bianchini,and Anna Maria Papini. Design and Synthesis of heme peptides for bioremediation. 29^th European Peptide Symposium, Gdansk, Poland, September 3-8, 2006, Abstract Th321.

[P114] V. Volkov, R. Chelli, R. Righini, F. Nuti, and A.M. Papini. Local structure and dynamics of phospholipid membranes investigated by two-dimensional IR spectroscopy and MD simulation. XXII Congresso Nazionale della Società Chimica Italiana, Firenze, September 10-15, 2006. Abstract FIS-P-134.

[P115] V. Volkov, F. Nuti, Y.Takaoka, R. Chelli, A.M. Papini, and R. Righini. Structure and bonding of water molecules in the polar region of phospholipid membrane investigated by two-dimensional IR spectroscopy and MD computer simulation. XXII Congresso Nazionale della Società Chimica Italiana, Firenze, September 10-15, 2006. Abstract FIS-P-135. Premio per il miglior poster della Divisione di Chimica Fisica.

[P116] F. Rizzolo, G. Sabatino, M.R. Moncelli, R. Guidelli, M. Chelli, and A.M. Papini, P.Rovero. A microwave-assisted synthesis of Gramicidin A for interaction studies in biomimetic membranes. XXII Congresso Nazionale della Società Chimica Italiana, Firenze, September 10-15, 2006. Abstract SBI-P-24.

2007

[P117]F. Real-Fernández,M. R. Moncelli, P. Rovero, A. M. Papini, Electrochemical studies of antigenic glycopeptides in biomimetic membranes, XIX International symposium on Bioelectrochemistry and Bioenergetics, BES 2007, Toulouse, France, 1-4 April 2007. B1-P10, Abstract p. 138.

[P118]F. Gori, B. Mulinacci, E. Bonchi, M. Chelli, F. Lolli, A.M. Papini and P. Rovero. Semi-synthesis of glucosylated recombinant MOG as auto-antigen in Multiple Sclerosis. VII European Symposium of The Protein Society, Stockholm, Sweden, May 12-16, 2007 .Abstract III-87.

[P119]A. Colson, J. Bayardon, E. Rémond, H. Lauréano, F. Nuti, R. Meunier-Prest, M. Kubicky, C. Darcel, A.M. Papini and S. Jugé. New b-Ferrocenyl Phosphino a-Aminoacids as Modular  Electrochemical Biomarkers for CSF114(Glyco)peptides. 17th international Conference on Phosphorus Chemistry, ICPC-17 sponsored by IUPAC, Xiamen (China), April 15-19, 2007. Poster P-176. Abstract Book p 228

[P120] F Nuti, E Peroni, B Mulinacci, I Paolini, MC Alcaro, F Benedetti, F Ciolli, F. Lolli, M Chelli, P. Rovero, AM Papini. An N-glucosylated peptide as multiple sclerosis antigenic probe to fishing out autoantibodies in serum and monitoring disease activity.

Benzon Symposium no. 54, Glycosylation opportunities in drug development, Copenhagen, Denmark,June 11-14, 2007. Abstract III-14

[P121] I. Paolini, M.C. Alcaro, F Nuti, P. Migliorini, F. Lolli, M. Chelli, P. Rovero, A.M. Papini. Glycosylated Peptides as Diagnostic Tools for Autoimmune Diseases: a Chemical Reverse Approach. Benzon Symposium no. 54, Glycosylation opportunities in drug development, Copenhagen, Denmark,June 11-14, 2007. Abstract III-13

[P122] M.C. Alcaro, F. Nuti, G. Bonechi, F. Benedetti, A. Carotenuto, C. Bonaccini, P. Gratteri, A. Tramontano, F. Lolli, M. Chelli, E. Novellino, P. Rovero, A.M. Papini

New Generation of Families of Antigenic Probes for Detection of Multiple Sclerosis Biomarkers. 20^th American Peptide Symposium, Montreal, Québec, June 26-30, 2007, Abstract PS2-381

[P123] F Nuti, E Peroni, B Mulinacci, I Paolini, MC Alcaro, F Benedetti, F Ciolli, F Lolli, M Chelli, P Rovero, A.M. Papini. Studies for identification of the minimal epitope(s) mimicked by the synthetic glucopeptide CSF114(Glc). 20^th American Peptide Symposium, Montreal, Québec, June 26-30, 2007, Abstract PS2-423

[P124] F. Real Fernández, A. Chamois-Colson, G. Bayardon, F.Nuti, E.Peroni, M.R. Moncelli, R. Meunier-Prest, S. Jugè, A.M.Papini. Synthesis of organometallic glycopeptides and electrochemical studies to detect autoantibodies in multiple sclerosis patients´ sera. 20^th American Peptide Symposium, Montreal, Québec, June 26-30, 2007, Abstract PS2 429. (semi-finalist participant in the Young Investigator Poster Competition-Peptide Idol).

[P125] M.A. Bonache, A. Le Chevalier, F. Nuti, E. Peroni, M. Chelli, P. Rovero, A.M. Papini. Ribose building block for the synthesis of glycopeptides to fishing out antibodies in autoimmune diseases. 20^th American Peptide Symposium, Montreal, Québec, June 26-30, 2007, Abstract PS2 463

[P126] F. Rizzolo, G. Sabatino, B. Kolesińska, Z.J. Kamiński, M.R. Moncelli, M. Chelli, P. Rovero and A.M. Papini. Optimized solid-phase synthesis of difficult peptide sequences: case study of Gramicidin A. 20^th American Peptide Symposium, Montreal, Québec, June 26-30, 2007, Abstract PS2-426.

[P127] S. Cantel, J.A. Halperin, M. Chorev, M. Scrima, A.M. D'Ursi, J. J. Levy, R.D. DiMarchi, A. Le Chevalier, P. Rovero, and A.M. Papini. Side chain-to-Side chain Cyclization by Intramolecular Click Reaction - Building Blocks, Solid Phase Synthesis and Conformational Characterization. 20^th American Peptide Symposium, Montreal, Québec, June 26-30, 2007, Abstract PS2-412.

[P128] S. Carganico, M.A. Bonache, M.C. Alcaro, M. Chelli, P. Rovero, A.M. Papini, M. Chorev, A. Lapolla, P. Traldi, Synthetic strategies to Advanced Glycation End products peptides involved in diabetes. 20^th American Peptide Symposium, Montreal, Québec, June 26-30, 2007, Abstract PS2-425.

[P129] E. Peroni, M. Tontini, B. Mulinacci, M. Chelli, P. Rovero and A.M. Papini A Glycopeptide-based Technique for Selective Antibodies Purification. 20^th American Peptide Symposium Montreal, Québec, June 26-30, 2007, Abstract PS2-509.

[P130] M.C. Alcaro, F. Barbetti, F. Nuti, I. Paolini, F. Real-Fernandez, A.M. Papini, and P. Rovero Evaluation of the Efficiency of Post-Translational Modified Peptide Libraries for Biomarkers Discovery. First International Symposium on Combinatorial Sciences in Biology, Chemistry, Catalysts and Materials, Firenze, Italy, July 15-18, 2007, Abstract PP21.

[P131] A. Le Chevalier, P. Rovero, M. Chorev, and A.M. Papini. Synthesis of N ^a-Protected w-Ynoic and w-Azido a-Amino Acids as Building Blocks for the Development of [1,2,3]Triazole Containing Peptide Libraries. Eurocombi4, Firenze, Italy, July 15-18, 2007, Abstract PP14.

[P132] S. Centi, E. Bulukin, M. Minunni, E. Peroni, A.M. Papini, P. Rovero, M. Mascini. “Glycopeptide-based electrochemical immunomagnetic sensors for antibody detection in sera from autoimmuno disease patients”. EUROanalysis XIV Conference, Antwerpen Belgium, September 9-14 2007. Abstract P123.

2008

[P133] A.M. Papini. Ferrocenyl glycopeptides as electrochemical probes to detect autoantibodies in multiple sclerosis patients’ sera. Third ERA Chemistry “Flash” Conference in Killarney, Ireland,.’Carbohydrates at the interfaces of biology, medicine and materials science' Killarney, Ireland, 9-13 March, 2008.

[P134] A.M. Papini (2008). Zervas Award Memorial Lecture. Peptide-based immunoassays for biomarkers detection: A challenge for translational research. 30^th European Peptide Symposium, 31 August-5 September 2008, Helsinki, Finland. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 8, ISSN: 1075-2617, doi: 10.1002/psc.1088.

[P135] Le Chevalier Isaad, M. Scrima, S. Cantel, J. Levy, P. Rovero, A.M. D'Ursi, M. Chorev, A.M. Papini (2008). Synthesis and conformational analysis of a series of cyclic i-to-i+4 side chain-to-side chain 1,4-disubstituted [1,2,3]triazolyl-bridged PTHrP(11-19) derivatives. 30^th European Peptide Symposium, 31 August-5 September 2008, Helsinki, Finland. Abstract Y04. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 3, ISSN: 1075-2617, doi: 10.1002/psc.1073.

[P136] F. Real-Fernández , A. Colson, J. Bayardon, F. Nuti, E. Peroni, R. Meunier-Prest, F. Lolli, M. Chelli, C. Darcel, S. Jugé, and A.M. Papini. Electrochemical Glycopeptide Probes to Detect Autoantibodies in Multiple Sclerosis Patients’ Sera. 30th European Peptide Symposium, Helsinki, Finland, August 31-September 6, 2008, Abstract P31501-022. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 136, ISSN: 1075-2617, doi: 10.1002/psc.1090.

[P137] E. Innocenti, E. Peroni, F. Nuti, M. Chelli, P. Rovero, C. Selmi, A.M.Papini.Post translational modified peptide-based ELISA to detect autoantibodies in Primary Biliary Cirrhosis. 30^th European Peptide Symposium, Helsinki, Finland, August 30-September 6, 2008, Abstract P30915-010. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 133, ISSN: 1075-2617, doi: 10.1002/psc.1090.

[P138] F. Nuti, N. Qvit, F. Rizzolo, M. Hurevich, A. Carotenuto, E. Peroni,M. Chelli, P. Rovero, C. Gilon and A.M. Papini. Microwave-assisted solid phase synthesis of backbone cyclic glycopeptide libraries. 30^th European Peptide Symposium, 31 August -5 September 2008, Helsinki,Finland. Abstract 30102-001.  JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(S), p. 131, ISSN: 1075-2617, doi: 10.1002/psc.1090.

[P139] G. Sabatino, F. Rizzolo, B. Kolesinska, M. Chelli, P. Rovero, Z.J. Kaminski, A.M. Papini (2008). Microwave-assisted attachment of Fmoc-amino acids to resins via triazine superactive esters. 30^th European Peptide Symposium, 31 August -5 September 2008, Helsinki, Finland. Abstract P10104-046. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(S), p. 58-59, ISSN: 1075-2617, doi: 10.1002/psc.1090.

[P140] F. Rizzolo, G. Sabatino, E. Perugia, M. Fridkin, M. Chelli, P. Rovero, A. M. Papini (2008). Microwave-assisted solid-phase synthesis of peptide probes to detect specific biomarkers: shifting off limitations affecting conventional synthetic strategies. 30^th European Peptide Symposium, 31 August -5 September 2008, Helsinki, Finland. Abstract 10417-110. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(S), p. 74-75, ISSN: 1075-2617, doi: 10.1002/psc.1090.

[P141] Di Cianni, D. D'Addona, F. Rizzolo, A.M. Papini, M. Ginanneschi (2008). On-resin microwaves-assisted Ring Closing Metathesis for the synthesis of Octreotide dicarba-analogues. 30^th European Peptide Symposium, 31 August -5 September 2008, Helsinki, Finland. Abstract P20104-012. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(S), p. 83, ISSN: 1075-2617, doi: 10.1002/psc.1090.

[P142] M. Scrima, A. Le Chevalier-Isaad, S. Chantel, J.J. Levy, P. Rovero, A.M. Papini, M. Chorev, A.M. D'Ursi (2008). A new library of cyclic peptides obtained via i-to-i+4 intramolecular side chain-to-side chain azide-alkyne 1,3-dipolar cycloaddition: CD and NMR conformational analysis. 30^th European Peptide Symposium, 31 August -5 September 2008, Helsinki,Finland. Abstract P22829-185. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 129, ISSN: 1075-2617, doi: 10.1002/psc.1090.

[P143] M.A. Bonache, F. Nuti, A. Le Chevalier-Isaad, E. Peroni, M. Chelli, P. Rovero, A.M. Papini (2008). New ribosylated building blocks useful for glycopeptide synthesis. 30^th European Peptide Symposium, 31 August -5 September 2008, Helsinki, Finland. Abstract 30208-003. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 131, ISSN: 1075-2617, doi: 10.1002/psc.1090.

[P144] M.C. Alcaro, I. Paolini, P. Fantini, F. Barbetti, M. Chelli, P. Migliorini, F. Lolli, P. Rovero, A.M. Papini (2008). A chemical reverse approach for autoimmune diseases diagnosis. 30^th European Peptide Symposium, 31 August -5 September 2008, Helsinki, Finland. Abstract P31509-024. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 137, ISSN: 1075-2617, doi: 10.1002/psc.1090.

[P145] A.M. Papini, P. Rovero, F. Lolli, M. Chelli, P. Migliorini (2008). Peptide-based a challenge for high performance diagnostics & prognostics of autoimmune diseases. 30^th European Peptide Symposium, 31 August -5 September 2008, Helsinki,Finland. Abstract P31509-025. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 137, ISSN: 1075-2617, doi: 10.1002/psc.1090.

[P146] A Le Chevalier-Isaad, M. Scrima, S. Cantel, P. Rovero, A.M. D'Ursi, M. Chorev, A.M. Papini. (2008). Synthesis of a series of cyclic i-to-i+4 side chain-to-side chain 1,4-disubstituted[1,2,3]triazolyl-bridged PTHrP(11-19) derivatives. 30^th European Peptide Symposium, 31 August -5 September 2008, Helsinki, Finland. Abstract P10100-020. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 52, ISSN: 1075-2617, doi: 10.1002/psc.1090.

2009

[P147] M. Frediani, D. Sémeril, F. Rizzolo, A.M. Papini, L. Rosi, M.Santella, P. Frediani, D. Matt “Lactide polymerization by acalix[4]arene titanium complex using conventional heating andmicrowave irradiation” XXVIII CONGRESSO INTERREGIONALE TUMA 2009, 20-22 September 2009, Pisa, Italy.

[P148] F. Nuti, Peroni E, Carganico S, Alcaro MC, Chelli M, Migliorini P, Selmi C, Lolli F, Chorev M, Rovero P, Papini AM Post translationally modified peptides for an efficient detection of autoantibody biomarkers of autoimmune diseases. 11th International Congress on Amino Acids, Peptides and Proteins, Vienna (Austria) 3-7 Agosto 2009

[P149] I. Friligou, F. Rizzolo, J. Matsoukas, T. Tselios, P. Rovero and A. M. Papini. Microwave assisted solid phase peptidesynthesis of a multiple antigen peptide (MAP) with two branches,containing the immunodominant epitope of rat myelin, MOG35-55. 10thInternational Conference in Medicinal Chemistry: Drug Design andDevelopment, 18-20 March 2009, Patras, Greece

[P150] Peroni E, F. Nuti, F. Real-Fernández, F. Lolli, Chelli M, Rovero P, Papini AM Improvement of autoantibody detection in multiple sclerosis by solid-phase glycopeptide based technologies. France-German meeting on multiple sclerosis “18th Francois Lhermitte’s Conferences “, Paris (France) March 6, 2009 Abstract IMM-20.

2010

[P151] I. S. Rice, P. M. Thompson, F. Nuti, A. M. Papini, A. D. Wallace Impact of DEHP Metabolites on Human Androgen Receptor Activity, 49th Annual Meeting of the Society of Toxicology, Salt Lake City (USA), March 7–11, 2010

[P152] C Testa, F Nuti, M Scrima, AM D’Ursi, N Lubin Germain, M Chorev, P Rovero, AM Papini. Probing the Bioactive Conformation of melanocortin like peptide by Click Reaction. Probes for peptide science: design and methodological development, April 8-9, 2010, Abstract P28

[P153] F Nuti, F. Real-Fernández, M. A Bonache, M Boccalini, S Chimichi, M Chelli, AM. Papini Glycopeptide probes for characterising immune response in neurological diseases: design and synthetic strategies, Probes for peptide science: design and methodological development, April 8-9, 2010, Abstract P19

[P154] E Peroni, F. Nuti, F. Real Fernández, F. Lolli, M. Chelli, P. Rovero, AM PapiniImprovement of Autoantibody Detection in Multiple Sclerosis by Solid-Phase Glycopeptide Based Technologies. Probes for peptide science: design and methodological development, April 8-9, 2010, Abstract P22

[P155] J.B. Chanson, I. Paolini, N. Collongues, M.C. Alcaro, F. Blanc, F. Barbetti, M. Fleury, E. Peroni, P. Rovero, G. Rudolf, F. Lolli, E. Trifilieff, A.M. Papini, J. de Seze. (2010). Evaluation of New Immunological Targets in Neuromyelitis Optica. . NEUROLOGY, vol. 74(9S2),  P-A390, ISSN: 0028-3878.

[P156] F Nuti, F. Real-Fernández, M. A Bonache, M Boccalini, S Chimichi, M Chelli, AM. PapiniMicrowave-assisted reaction of building blocks for glycopeptides synthesis. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P057.

[P157] F. Rizzolo, F. Nuti, S. Pandey, M. Chelli, P. Rovero, and AM. Papini Microwave-assisted solid phase synthesis of [Asn641(Glc)]FAN(635-655): a new case study for optimisation of glycopeptide synthesis. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P106.

[P158] M. Scrima, P. Rovero, A.M. Papini, M. Chorev, A.M. D'Ursi. Molecular dynamics calculation and NMR conformational studies of heterodetic triazolyl cyclo-nonapeptides: a comparative study. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P144.

[P159] S. Pandey, E. Peroni, MC Alcaro, F. Rizzolo, F. Nuti, M. Chelli, S Matà, P. Rovero, F. Lolli, AM. Papini. Mimicry effect of the neo-epitope [Asn641(Glc)]FAN(635-655) with CSF114(Glc) detecting autoantibodies in Multiple Sclerosis. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract O1.

[P160] S. Pandey, D. Lambardi, F. Real Fernández, M. C. Alcaro, I. Doni, E. Peroni, M. Chelli, F. Lolli, A.M. Papini, P. Rovero. Identification of cytoskeletal proteins monoclonal anbibodies recognized by CSF114(Glc), the synthetic probe of multiple sclerosis.Italian Proteomics Association, 5^th annual national conference (ItPA), Firenze (Italy), 9-12 July, 2010. Abstract p.1.59.

[P161] F. Real-Fernández, I. Passalacqua, E. Peroni, F. Lolli, P. Rovero, A.M. Papini. A surface-plasmon resonance-based label-free in vitro serodiagnostic technology for multiple sclerosis. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P403.

[P162] F. Real-Fernández, I. Passalacqua, E. Peroni, F. Lolli, P. Rovero, A.M. Papini. Characterisation of the minimal epitope detecting autoantibodies in Multiple Sclerosis by surface plasmon resonance. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P404.

[P163] S. Pandey, D. Lambardi, M.C. Alcaro, F. R. Fernández, E. Peroni, P. Rovero, M. Chelli, F. Lolli, A.M. Papini. Identification of cytoskeletal proteins monoclonal antibodies recognized by CSF114(Glc), the synthetic probe of Multiple Sclerosis. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P206.

[P164] C. Testa, F. Nuti, M. Scrima, A.M. D’Ursi, N. Lubin-Germain, M. Chorev, P. Rovero, A.M. Papini. Stabilization of beta-turn conformation in melanocortin like peptide by click reaction. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract O8.

[P165] F. Rizzolo, C. Testa, M. Chorev, M. Chelli, P. Rovero, A.M. Papini. Conventional and microwave-assisted SPPS approach: a comparative study of PTHrP(1-34)NH₂ synthesis. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P107.

[P166] S. Carganico, N. Zanella, G. Sabatino, P. Rovero, M. Chorev, A.M. Papini. A novel diagnostic-prognostic tool for diabetes: UPLC analysis of glycated metabolites. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P379.

[P167] M. Di Pisa, G. Sabatino, M. Chelli, P. Rovero, C. Tiberti, A.M. Papini.Celiac disease: characterization of linear autoantigenic epitopes.31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P399.

[P168] G. Sabatino, M. Di Pisa, M. Chelli, P. Rovero, C. Tiberti, and A. M. Papini. Celiac disease: characterization of amino acids/short peptides finger print for a fast I.V.D. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P400.

[P169] L.M. Lumini, G. Cane, A. Di Cianni, A.M. Papini, and M. Ginanneschi. A study on the microwaves synthesis of the somatostatin dicarba-analogues. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P105

[P170] F. Nuti, F. Rizzolo, F. Gori, M. Chelli, P. Rovero, L. Moroder, A.M. Papini. Microwave-assisted solid phase synthesis of collagen peptides. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P110

[P171] F. Gori, B. Mulinacci, L. Massai, F. Lolli, A.M. Papini, P. Rovero. Antigenic probes for autoantibody detection in Multiple Sclerosis: synthetic peptides versus recombinant proteins. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P-405.

[P172] S. Pandey, E. Peroni, P. Rovero, F. Lolli, M. Chelli, A. M. D’Ursi and A. M. Papini. Rational design and optimization of newly designed glycopeptide to develop the diagnostic/prognostic assays for Multiple Sclerosis. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P407.

[P173]  E. Peroni, N. Brodie Linder, A.M. Papini. On-silica peptide probes: innovative in vitro diagnostic devices for detection of antibodies as biomarkers of autoimmune diseases. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P471.

[P174] P. Fantini, M.C. Alcaro, I. Paolini, F. Barbetti, D. Valoriani, A.M. Papini, F. Lolli, P. Rovero, F. Pratesi, P. Migliorini. The 'Chemical Reverse Approach' to identify autoantibodies in Systemic Lupus Erithematosus patients. 31st European Peptide Symposium, Copenhagen (Denmark), September 5-9, 2010. Abstract P398.

2011

[P175] Testa, C., Carganico, S., Scrima, M., D’Ursi, A.M., Germain, N.L., Chorev, M., Rovero, P., and Papini, A.M..Biological studies of synthesized homologues of melanocortin hormones 2nd PhD Day, University of Florence, Sesto Fiorentino, Florence (Italy), 18 May 2011

[P176] ME Street, A.M Papini, C. Testa, F. Nuti, E. Grossi, S Bernasconi Relationships between urinary concentrations of PHTALOX, obesity and insulin sensitivity in obese children: a pilot study. The Obese Species workshop, Erice Italy 21-26 October 2011.

[P177] F. Real-Fernández, F. Nuti, M.Angeles Bonache, M. Boccalini, S. Chimichi, M. Chelli, and AM. Papini. Controlled microwave-assisted coupling reaction to obtain glycosylated aspartic acid. International Microwave-Assisted Organic and Peptide Synthesis Symposium, Firenze (Italy), April 27-29, 2011 Abstract PP-9

[P178] Y. Cao, C. Tiberi, F. Nuti, E. Peroni, J.Uziel, and A.M. Papini. A convergent microwave-assisted approach for solid-phase synthesis of O-glycopeptide sequences. International Microwave-Assisted Organic and Peptide Synthesis Symposium, Firenze (Italy), April 27-29, 2011 Abstract PP-12.

[P179] M Di Pisa,G Sabatino,M Chelli,P. Rovero,and A.M. Papini Characterization of linear autoantigenic epitopes in CeliacDisease MW assisted and conventional solid phase synthesis. International Microwave-Assisted Organic and Peptide Synthesis Symposium, Firenze (Italy), April 27-29, 2011 Abstract PP-14

[P180] G. Cane, M. Lumini, A.M. Papini and M. Ginanneschi Microwave-assisted RCM in the synthesis of Somatostatin dicarba-analogues. A case study MW assisted and conventional solid phase synthesis. International Microwave-Assisted Organic and Peptide Synthesis Symposium, Firenze (Italy), April 27-29, 2011 Abstract PP-10

[P181] G. Sizun-Thome, G.Sabatino, B.Gatto, E. Peroni, Paolo Rovero, A.M. Papini.Solid-phase synthesis of NCp7(12-55) peptide: a comparison between MW assisted and conventional solid phase synthesis. International Microwave-Assisted Organic and Peptide Synthesis Symposium, Firenze (Italy), April 27-29, 2011 Abstract PP-11

[P182] O. Monasson C. Rentier, F. Rizzolo, E. Peroni, and A.M. Papini. Microwave-assisted solid-phase synthesis of peptide probes to detect specific biomarkers: shifting off limitations affecting conventional synthetic strategies.International Microwave-Assisted Organic and Peptide Synthesis Symposium, Firenze (Italy), April 27-29, 2011 Abstract PP-13

[P183] F. Rizzolo, C. Testa, M. Chorev, M. Chelli, P. Rovero, A. M. Papini, Conventional and microwave-assisted SPPS of PTHrP(1-34)NH₂ - A comparative study.2nd International Microwave-Assisted Organic and Peptide Synthesis Symposium, MAOPS2, Florence (Italy), 27-29 April 2011. Abstract FP-4

[P184] I. Friligou1, F. Rizzolo , T Tselios, J Matsoukas, P Rovero, and A.M. Papini Protocol for Microwave-Assisted Convergent and Divergent Synthesis of Multiple Antigen Peptide Systems (MAPs) 2nd International Microwave-Assisted Organic and Peptide Synthesis Symposium, MAOPS2, Florence (Italy), 27-29 April 2011. Abstract FP-6

2012

[P185] Testa, C., D’Addona, D., Scrima, M., D’Ursi, A.M., Dirain, M.L., Chorev, M., Haskell-Luevano, C., Rovero, P., Papini, A.M. SAR studies of triazolyl-containing cyclopeptides: A defined β-turn structure increases potency and selectivity to melanocortin receptor subtypes. 32ndEuropean Peptide Symposium, Athens (Greece), 2-7 September 2012. Abstract-P-301

[P186] Rentier, C., Nuti, F., Monasson, O., Rossi, G., Pacini, G., Sabatino, G., Rovero, P., Papini, A.M. Post-translationally modified peptides for diagnostics and follow-up of autoimmune diseases.University of Florence 1st year Ph.D. students (cycle XXVII), Florence, (Italy), December 17 2012

[P187] Larregola, M., Pacini, G., Rizzolo, F., Burlina, F., Lavielle, S., Rovero, P., Papini, A.M. Towards semi-synthetic N-glucosylated MOG to identify aberrantly modified native protein autoantigens in multiple sclerosis 2^nd Austrian Peptide Symposium, Vienna (Austria), November 29 2012

[P188] Rentier, C., Monasson, O., Nuti, F., Traldi, P., Lapolla, A., Larregola, M., Rovero, P., Papini, A.M. Synthesis of post-translationally modified peptides for detection of autoantibodies in diabetic patients’ sera 32^nd European Peptide Symposium, Atene (Grecia),Settembre 2-7, 2012. Abstract P-032

[P189] Cao, Y., Nuti, F., Rossi, G., Uziel, J., Rovero, P., Papini, A.M. Synthesis of peptides and sulfated monosaccharides able to identify antibodies in IgM monoclonal gammopathy 32^nd European Peptide Symposium, Athens (Greece), September 2-7, 2012 Abstract P-118.

[P190] Y. Cao, F. Nuti, C. Tiberi, J. Uziel, P. Rovero, A.M. Papini. Synthesis of building blocks for the synthesis of glycopeptides to detect anti-ganglioside antibodies in Amyotrophic Lateral Sclerosis. 32^nd European Peptide Symposium, Athens (Greece), September 2-7, 2012 Abstract P-117.

[P191] Nuti, F., Real-Fernandez, F., Pandey, S., Hayek, J., De Felice, C., Lavielle, S., Larregola, M., Rovero, P., Papini, A.M. Autoantibodies to N-glucosylated peptide sequons in Rett syndrome: the first insight to disclose an autoimmune mechanism 32^nd European Peptide Symposium, Athens (Greece), September 2-7, 2012 Abstract P-218

[P192] Rentier, C., Nuti, F., Pacini, G., Rovero, P., Selmi, C., Papini, A.M. Synthesis of diastereoisomeric modified amino acids derived from -lipoic acid for use in solid phase peptide synthesis 32^nd European Peptide Symposium, Athens (Greece), September 2-7, 2012 Abstract-P-362.

[P193] Larregola, M., Pacini, G., Rizzolo, F., Burlina, F., Lavielle, S., Rovero, P., Papini, A.M.  Towards semi-synthetic N-glucosylated MOG to identify aberrantly modified native protein autoantigens in multiple sclerosis 32^nd European Peptide Symposium, Athens (Greece), September 2-7 2012 Abstract-P-119

[P194] Monasson, O., Rizzolo, F., Traldi, P., Lapolla, A., Papini, A.M. Design and synthesis of new peptide scaffold presenting AGEs as diagnostic tool to monitor biomarkers in diabetes 32^nd European Peptide Symposium, Athens (Greece), September 2-7 2012 Abstract-P-339

[P195] Rizzolo, F., Testa, C., Lambardi, D., Chorev, M., Chelli, M., Rovero, P., Papini, A.M.. Fast and efficient microwave-assisted monitoring of difficult peptide sequences. 32^nd European Peptide Symposium, Athens (Greece), September 2-7 2012 Abstract-P-202

[P196] C. Tiberi, G. Sabatino, M. Di Pisa, P. Rovero, A.M. Papini. SPPS of glucosylated multiple antigen peptides (MAPs) as synthetic probes for detection of autoantibodies in multiple sclerosis patients’ sera. 32^nd European Peptide Symposium, Athens (Greece), September 2-7 2012 Abstract-P-359

[P197] M. Di Pisa, G. Sabatino, M. Chelli, P. Rovero, A.M. Papini. (2012). Synthesis of newly designed peptides for the diagnosis of Celiac Disease. 32^nd European Peptide Symposium, Athens (Greece), September 2-7 2012 Abstract-P-364.

[P198] G. Sabatino, F. Di Pisa, M. Potenza, L. Dei, A.M. Papini. (2012). UPLC-based amino acid analysis of paintings and statistical analysis of chromatographic profiles for conservation of cultural heritage. 32^nd European Peptide Symposium, Athens (Greece), September 2-7 2012, Abstract-P-373.

[P199] Larregola, M., Papini,A.M. The importance of a “Chemical Reverse Approach” to detect biomarkers of immune‑mediated diseases. 13^th Naples Workshop on Bioactive Peptides, Naples (Italy), June 7-10 2012

[P200] Larregola, M., Papini,A.M. “Chemical Reverse Approach” to detect biomarkers of immune-mediated diseases. 3rd ERI-ICP conference "Death, Danger, Inflammation and Immunity", Institut Pasteur, Paris (France), May 31-June 1 2012

[P201] Larregola, M., Papini, A.M.The importance of a “Chemical Reverse Approach” to detect biomarkers of immune‑mediated diseases. Gordon Research Conference on Peptides, Chemistry & Biology, Ventura, CA (USA), February 19-24 2012

[P202] A. Pratesi, C. Gabbiani, M. Ginanneschi, A.M. Papini, L. Messori Reactions of Cytotoxic Gold(I) and Gold(III) Complexes with the Active Site of Thioredoxin Reductase. Atti del 12th Workshop on PharmacoBioMetallics – BIOMET12, pag. 71 – P15, Padova, 26-28 Ottobre 2012.

2013

[P203] C. Rentier. and A.M. Papini Synthesis of modified peptides to set-up diagnostic tests for autoimmune diseases. Presentation session for “Les Doctoriales”, Vélizy-Villacoublay (France), June 17, 2012.

[P204] C. Rentier, O. Monasson, F. Nuti, E. Peroni, G. Pacini, G. Rossi, M. Larregola, P. Rovero, and A.M. Papini Synthesis of lipoylated lysines ready for SPPS to be used as post-translational modifications in peptidomimetics for immune-related diseases diagnostics. Journées de Chimie Organique de la Societé Chimique de France 2013, Ecole Polytechnique, Palaiseau (France),September 24-26, 2013. Abstract P278, pag. 380.

[P205] C. Rentier, F. Nuti, E. Peroni, G. Pacini, P. Rovero, and A.M. Papini. Preparation of peptide-resin conjugates to remove pathogenic antibodies from autoimmune diseases patients’ sera: the case of Primary Biliary Cirrhosis.PepMat 2013, October 28-31, 2013, Sorrento (Italy). Abstract P37.

[P206]M. Di Pisa, G. Sabatino, P. Rovero, and A.M. Papini. Epitope mapping of N-terminal portion of tissue transglutaminase protein antigen to identify linear epitopes in coeliac disease. 18ème GFPP, Sète (France), 26-31 May 2013.

[P207]N. Auberger, M. Di Pisa, M. Larregola, O. Lequin, E. Peroni, A.M. Papini, G. Chassaing, J.M. Mallet, and S. Lavielle. Synthesis of new cyclo(glyco)peptides for the diagnosis of autoimmune diseases. 18ème GFPP, Sète (France), 26-31 May 2013.

[P208]M. T. C. Walvoort, C. Testa, G. Pacini, G. Rossi, A. M. Papini, B. Imperiali. Protein Glycosylation in Bacteria A New Variation on an Old Theme. MIT Bio-Retreat, 10-11 June 2013 Sea Crest Beach Hotel (Falmouth), USA.

2014

[P209]C. Rentier, G. Pacini, G. Rossi, F. Nuti, E. Peroni, M. Larregola, C. Selmi, P. Rovero and A.M. Papini. Post-translationally modified peptides for diagnostics and follow-up of autoimmune diseases. Frontiers of Chemical Biology: investigating life with Chemistry, June 6th 2014, Paris (France).

[P210] M. Di Pisa, N. Auberger, M. Larregola, G. Chassaing, E. Peroni, S. Lavielle, A.M. Papini, O. Lequin, J.-M. Mallet. Glaser Oxidative Coupling on Peptides: Stabilization of β-Turn Structure. PD04, RICT 2014, Rouen, 2-4 July 2014, Awarded with a Poster Prize by the SCT (Société de Chimie Thérapeutique).

[P211] V. Doan, G. Chaume, F. Rizzolo, E. Peroni, A-M. Papini, S. Kara, S. Afonin, E. Strandberg, A. Ulrich, T. Brigaud. SOLID PHASE PEPTIDE SYNTHESIS OF A 19F-LABELED HARZIANIN: AN ANTIMICROBIAL PEPTAIBOL. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract YP38, p. 107-108.

[P212] D. Petkova, B. Yanachkova, O.Monasson, A-M. Papini, I. Stoineva. SHORT SYNTHETIC PEPTIDES AS INHIBITORS OF ANGIOTENSIN CONVERTIN ENZYME. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract P011, p. 122.

[P213] C. Rentier, O. Monasson, Z. Ferhat, F. Nuti, G. Sabatino, M. Larregola, E. Peroni and A.M. Papini. COMPARATIVE STUDY OF METHIONINE OXIDATION IN SELECTED PEPTIDE SEQUENCES. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract P022, p. 128.

[P214] S. Pascarella, F. Melani, L. Giovannelli, A. M. Papini, P. Rovero. MIMICKING SERIN PROTEASE INHIBITOR H1 CHAPERONE FUNCTION IN COLLAGEN BIOSYTNHETIC PATHWAY VIA THE TEMPLATE ASSEMBLED SYNTHETIC PROTEIN APPROACH. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract P100, p. 173-174.

[P215] D. Uber, J. Makowska, C. Tiberi, A- M. Papini, L. Chmurzyński. SYNTHESIS AND CONFORMATION ALANALYSIS OF PEPTIDES DERIVED FROM HUMAN PIN1 PROTEIN (WW DOMAIN). 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract P131, p. 192-193.

[P216] S. Pascarella, C. Tiberi, L. Giovannelli, L. Pino, A. M. Papini, P. Rovero. DESIGN, SYNTHESIS AND BIOLOGICAL CHARACTERIZATION OF COLLAGEN TURNOVER MODULATORS: DEGRADATION INHIBITOR AND PRODUCTION ENHANCER PEPTIDES. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract P193, p. 230.

[P217] M. Ieronymaki, M. Larregola, G. Pacini, F. Burlina, S. Lavielle, J. Offer, P. Rovero, and A.M. Papini. SEMI-SYNTHETIC STRATEGY TO OBTAIN ABERRANTLY N-GLUCOSYLATED MYELIN OLIGODENDROCYTE GLYCOPROTEIN: PART I: OPTIMIZATION OF THE SYNTHESIS OF Asn31(Glc)hMOG(1-34). 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract P208, p. 239-240.

[P218] M. Ieronymaki,  E. Peroni, F. Nuti, G. Rossi, P. Rovero, and A.M. Papini. SYNTHETIC STRATEGIES TO CYCLIC PEPTIDE MIMICS OF HNK-1, A POSSIBLE SYNTHETIC ANTIGENIC PROBES FOR CHRONIC DEMYELINATION DISEASE DIAGNOSTICS. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract P209, p. 240-241.

[P219] C. Rentier, G. Rossi, F. Nuti, A. Lapolla, P. Traldi, P. Rovero and A.M. Papini. KYNURENINE: A POST-TRANSLATIONAL MODIFICATION POSSIBLY INVOLVED IN MULTIPLE SCLEROSIS. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract P217, p. 245.

[P220] G. Rossi, F. Real-Fernández, F. Panza, F. Pratesi, P. Migliorini, A.M. Papini, P. Rovero. BIOSENSOR CHARACTERIZATION OF THE INTERACTION BETWEEN SYNTHETIC CITRULLINATED PEPTIDES AND AUTOANTIBODIES IN RHEUMATOID ARTHRITIS PATIENTS’ SERA. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract P219, p. 246-247.

[P221] F. Real-Fernández, G. Rossi, F. Niccheri, M. Ramazzotti, D. Degl’Innocenti, F. Lolli, A.M. Papini and P. Rovero. CHARACTERIZATION OF RECOMBINANT HUMAN DOMAIN ANTIBODIES BY SURFACE PLASMON RESONANCE. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract P220, p. 247.

[P222] G. Pacini, C. Rentier, F. Nuti, E. Peroni, F. Real Fernàndez, P.M. Battezzati, C. Selmi, P.

Rovero  and A.M. Papini. DETECTION OF AUTOANTIBODIES IN PRIMARY BILIARY CIRRHOSIS USING PEPTIDES OF THE DIHYDROLIPOAMIDE ACETYLTRANSFERASE. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract P221, p. 247-248.

[P223] G. Pacini, M. Larregola, M. Ieronymaki, A.M. Papini, and P. Rovero. SEMI-SYNTHETIC STRATEGY TO OBTAIN ABERRANTLY N-GLUCOSYLATED MYELIN OLIGODENDROCYTE GLYCOPROTEIN: PART II: EXPRESSION OF RECOMBINANT FRAGMENT hMOG(35-117). 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract P255, p. 269-270.

[P224] E. Peroni,  W. Bellagha-Chenchah, F. Real Fernandez , P. Rovero, Z. Ferhat, C. Sella, L. Thouin, C. Amatore, A.M. Papini. INNOVATIVE ELECTROCHEMICAL DIAGNOSTIC DEVICES BASED ON SYNTHETIC CONFORMATIONAL PEPTIDE EPITOPE MIMICS. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Abstract P311, p. 304-305.

[P225] E. Koenig, A.M. Papini. Anti-Galectin-Autoantibodies as Biomarkers in Autoimmune Diseases and Cancer. Peptides in Paris – PIPS 2014, Institute of Advanced Studies, Gennevilliers site of the University of Cergy-Pontoise (France). October 5-8, 2014. Abstract P1, p. 51.

[P226] V. Doan, G. Chaume, A. Bordessa, F. Rizzolo, E. Peroni, A-M. Papini, S. Kara, S. Afonin, A. Ulrich, T. Brigaud. Solid Phase Peptide Synthesis of a 19F-Labeled Harzianin: an Antimicrobial Peptaibol. Peptides in Paris – PIPS 2014, Institute of Advanced Studies, Gennevilliers site of the University of Cergy-Pontoise (france).. October 5-8, 2014. Abstract P7, p. 57.

[P227] Y. Cao, G. Rossi, F. Nuti, P. Rovero, J. Uziel and A.M. Papini. Sugar and Peptide Mimics for SPR Characterization of Autoantibodies in Monoclonal Gammopathy. Peptides in Paris – PIPS 2014, Institute of Advanced Studies, Gennevilliers site of the University of Cergy-Pontoise (France). October 5-8, 2014. Abstract P8, p. 58.

[P228] M. Ieronymaki, M. Larregola, G. Pacini, F. Burlina, S. Lavielle, J. Offer, P. Rovero, and A.-M. Papini. Semi-Synthetic Strategy to Obtain Aberrantly N-Glucosylated Myelin Oligodendrocyte Glycoprotein: Part I: Optimization of the Synthesis of Asn31(Glc)hMOG(1-34). Peptides in Paris – PIPS 2014, Institute of Advanced Studies, Gennevilliers site of the University of Cergy-Pontoise (France). October 5-8, 2014. Abstract P12, p. 62.

[P229] C. Rentier, G. Pacini, G. Rossi, F. Nuti, E. Peroni, M. Larregola, C. Selmi, P. Rovero and A.M.Papini. Post-Translationally Modified Peptides for Diagnostics and Follow-Up of Autoimmune Diseases. Peptides in Paris – PIPS 2014, Institute of Advanced Studies, Gennevilliers site of the University of Cergy-Pontoise (France). October 5-8, 2014. Abstract P15, p. 65.

[P230] G. Pacini, M. Larregola, M. Ieronymaki, A.M. Papini, and P. Rovero. Semi-Synthetic Strategy to Obtain Aberrantly N-Glucosylated Myelin Oligodendrocyte Glycoprotein: Part II: Expression of Recombinant Fragment hMOG(35-117). Peptides in Paris – PIPS 2014, Institute of Advanced Studies, Gennevilliers site of the University of Cergy-Pontoise (France). October 5-8, 2014. Abstract P16, p. 66.

[P231] E. Peroni, G. Sabatino, F. Nuti ,P. Rovero, F. Lolli, and A.M. Papini. The “Chemical Reverse Approach”: from N-Glucosylated Beta-Turn Peptide Structures Mimicking Conformational Epitopes to Novel Protein Autoantigens of Multiple Sclerosis. Peptides in Paris – PIPS 2014, Institute of Advanced Studies, Gennevilliers site of the University of Cergy-Pontoise (France). October 5-8, 2014. Abstract P17, p. 67.

2015

[P232] Pascarella, Simona; Tiberi, Caterina; Sabatino, Giuseppina; Nuti, F; Papini, AM; Giovannelli, L; Rovero, P. SerpinA1 C-Terminal Peptides as Collagen Turnover Modulators CHEMMEDCHEM 11(SI) (16) P: 1850-1855 23^rd National Meeting of the Medicinal-Chemistry-Division of the Italian-Chemical-Society (DCF-SCI): Salerno, (ITALY) Date: 2015.

[P233] Makowska, J;Uber, D;Zmudzinska, W; Tiberi, C; Chmurzynski, L;Papini, AM. Conformational analysis of fragments of the human Pin1 protein: the influence of charged amino-acid residues on the beta-hairpin structure PROTEIN SCIENCE 24(SI) (1) P:86 Meeting Abstract: PD-026 29^th Annual Symposium of the Protein-Society Barcelona, SPAIN JUL 22-25, 2015

2016

[P234] Larregola M.; Monasson O; Ieronymaki M.; SackoS.; Pantelia A.; Nuti F.; Burlina F.; Lavielle S.; Offer J.; Rovero P.; Papini A.M. Synthesis of N-Glucosylated Myelin Oligodendrocyte glycoprotein: a challenging route J Pept Sci 22(S1) 52 p: 67 Meeting Abstract: PP-025. 34^th European Peptide Symposium, Leipzig (Germany), 4-9 September, 2016.

[P235] O. Monasson, M. Larregola, M. Ieronymaki, S. Sacko, A. Pantelia, F. Nuti, F. Burlina, S. Lavielle, J. Offer, P. Rovero, A.M. Papini. Synthesis of N-glucosylated Myelin Oligodendrocyte Glycoprotein: a challenging route. 15^th Naples Workshop on Bioactive Peptides, Naples (Italy) 23-25 June 2016.

2018

[P236] A. Mazzoleni, C. Testa, S. Francesconi, S. Lavielle, P. Rovero, J.-M. Mallet, and A.M. Papini. Synthesis and characterisation of glucosylated peptides: toward selective plasmapheresis-based treatment of Multiple Sclerosis. 16^th Naples Workshop on Bioactive Peptides, Naples (Italy) June 7-9, 2018. Poster P04.

[P237] B. Dalla Volta, G. Sabatino, A. Grammatikopoulos, M. Vignoli, A.M. Papini, G. Pappalardo, P. Rovero, A. Kapurniotu. Conformationally constrained analogues of amyloidogenic segments of Islet Amyloid Polypeptide. 16^th Naples Workshop on Bioactive Peptides, Naples (Italy) June 7-9, 2018. Poster P28.

[P238] F. Real-Fernandez, I. Guryanov, N. Prisco, G. Sabatino, B. Biondi, F. Formaggio, A.M. Papini, T. Tennikova, and P. Rovero. Peptide sto study HIV-1 and CCR5 interactions by surface plasmon resonance. 16^th Naples Workshop on Bioactive Peptides, Naples (Italy) June 7-9, 2018. Poster P36.

[P239] H. Rusche, Z. Kukacka, L. Lupu, L. Altamore, F. Bori, S. Maeser, J. Hennermann, M. Przybylski, and A.M. Papini. Antibody epitope of human a-galactosidase A revealed by affinity-mass spectrometry. 16^th Naples Workshop on Bioactive Peptides, Naples (Italy) June 7-9, 2018. Poster P45.

[P240] L. Altamore, C. Testa, F. Real-Fernandez, G. Sabatino, R. Bechara, M. Pallardy, A. Lapolla, C. Selmi, F. Borri, M. Przybylski, J. Hayek, P. Rovero, and A.M. Papini. Use of peptide mimetics of proteins to characterise immune response in different pathologies: a powerful approach. 16th Naples Workshop on Bioactive Peptides, Naples (Italy) June 7-9, 2018. Poster P47.

[P241] H. Rusche, Z. Kukacka, L. Lupu, L. Altamore, F. Bori, S. Maeser, J. Hennermann, M. Przybylski, and A.M. Papini. Antibody epitope of human a-galactosidase A revealed by affinity-mass spectrometry. 35th European Peptide Symposium, University College Dublin (Ireland) August 26-31, 2018. Poster P155.

[P242] F. Errante, S. Pascarella, C. Cipriani, L. Giovannelli, A.M. Papini, P. Rovero. Serpin A1 derivatives as Collagen turnover modulators for cosmeceutical uses. 35th European Peptide Symposium, University College Dublin (Ireland) August 26-31, 2018. Poster P158.

Abstracts in J Pept Science, Biopolymers, Peptide Science

(Period 2008-2017)

2008

[A1]F. Real-Fernández , A. Colson, J. Bayardon, F. Nuti, E. Peroni, R. Meunier-Prest, F. Lolli, M. Chelli, C. Darcel, S. Jugé, and A.M. Papini. Electrochemical Glycopeptide Probes to Detect Autoantibodies in Multiple Sclerosis Patients’ Sera. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 136, ISSN: 1075-2617, doi: 10.1002/psc.1090

[A2]E. Innocenti, E. Peroni, F. Nuti, M. Chelli, P. Rovero, C. Selmi, A.M.Papini.Post translational modified peptide-based ELISA to detect autoantibodies in Primary Biliary Cirrhosis. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 133, ISSN: 1075-2617, doi: 10.1002/psc.1090

[A3]A.M. Papini (2008). Zervas Award Memorial Lecture. Peptide-based immunoassays for biomarkers detection: A challenge for translational research. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 8, ISSN: 1075-2617, doi: 10.1002/psc.1088.

[A4]Le Chevalier Isaad, M. Scrima, S. Cantel, J. Levy, P. Rovero, A.M. D'Ursi, M. Chorev, A.M. Papini (2008). Synthesis and conformational analysis of a series of cyclic i-to-i+4 side chain-to-side chain 1,4-disubstituted [1,2,3]triazolyl-bridged PTHrP(11-19) derivatives JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 3, ISSN: 1075-2617, doi: 10.1002/psc.1073.

[A5]F. Rizzolo, G. Sabatino, E. Perugia, M. Fridkin, M. Chelli, P. Roveroand A.M. Papini. Microwave-assisted solid-phase synthesis of peptideprobes to detect specific biomarkers: shifting off limitationsaffecting conventional synthetic strategies. 30th European PeptideSymposium, 31 August -5 September 2008, Helsinki, Finland.

[A6]F. Nuti, N. Qvit, F. Rizzolo, M. Hurevich, A. Carotenuto, E. Peroni,M. Chelli, P. Rovero, C. Gilon and A.M. Papini. Microwave-assistedsolid phase synthesis of backbone cyclic glycopeptide libraries. 30thEuropean Peptide Symposium, 31 August -5 September 2008, Helsinki,Finland. Abstract.  JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(S), p. 131, ISSN: 1075-2617, doi: 10.1002/psc.1090

[A7]G. Sabatino, F. Rizzolo, B. Kolesińska, M. Chelli, P. Rovero, Z. J. Kamiński, and A.M. Papini.Microwave-assisted attachment of Fmoc-amino acids to resins viatriazine “superactive esters”. 30th European Peptide Symposium, 31August -5 September 2008, Helsinki, Finland.

[A8]A. Di Cianni, D. D’Addona, F. Rizzolo, A.M. Papini, and M. Ginanneschi. On-resin microwaves-assisted Ring Closing Metathesis for the synthesis of Octreotide dicarba-analogues. 30th European Peptide Symposium, Helsinki (Finland), August 31-September 5, 2008, J. Pept. Sci. 14(Suppl), P20104-012, 83.

2010

[A9]F Nuti, F. Real-Fernández, M. A Bonache, M Boccalini, S Chimichi, M Chelli, AM. PapiniMicrowave-assisted reaction of building blocks for glycopeptides synthesis. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 64, ISSN: 1075-2617, doi: 10.1002/psc.1303

[A10]F. Rizzolo, I. Bartolini, F. Nuti, S. Pandey, M. Chelli, P. Rovero, and AM. Papini Microwave-assisted solid phase synthesis of [Asn641(Glc)]FAN(635-655): a new case study for optimisation of glycopeptide synthesis. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 78, ISSN: 1075-2617, doi:10.1002/psc.1303

[A11]M. Scrima, P. Rovero, A.M. Papini, M. Chorev, A.M. D'Ursi. Molecular dynamics calculation and NMR conformational studies of heterodetic triazolyl cyclo-nonapeptides: a comparative study. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 91-92, ISSN: 1075-2617, doi: 10.1002/psc.1303

[A12]S. Pandey, E. Peroni, MC Alcaro, F. Rizzolo, F. Nuti, M. Chelli, S Matà, P. Rovero, F. Lolli, AM. Papini. Mimicry effect of the neo-epitope [Asn641(Glc)]FAN(635-655) with CSF114(Glc) detecting autoantibodies in Multiple Sclerosis. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 26, ISSN: 1075-2617, doi: 0.1002/psc.1301.

[A13]S. Pandey, D. Lambardi, F. Real Fernández, M. C. Alcaro, I. Doni, E. Peroni, M. Chelli, F. Lolli, A.M. Papini, P. Rovero. Identification of cytoskeletal proteins monoclonal anbibodies recognized by CSF114(Glc), the synthetic probe of multiple sclerosis.Italian Proteomics Association, 5^th annual national conference (ItPA), Firenze (Italy), 9-12 July, 2010. Abstract p.1.59.

[A14]F. Real-Fernández, I. Passalacqua, E. Peroni, F. Lolli, P. Rovero, A.M. Papini. A surface-plasmon resonance-based label-free in vitro serodiagnostic technology for multiple sclerosis. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 177, ISSN: 1075-2617, doi: 10.1002/psc.1303

[A15]F. Real-Fernández, I. Passalacqua, E. Peroni, F. Lolli, P. Rovero, A.M. Papini. Characterisation of the minimal epitope detecting autoantibodies in Multiple Sclerosis by surface plasmon resonance. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 177-178, ISSN: 1075-2617, doi: 10.1002/psc.1303

[A16]S. Pandey, D. Lambardi, M.C. Alcaro, F. R. Fernández, E. Peroni, P. Rovero, M. Chelli, F. Lolli, A.M. Papini. Identification of cytoskeletal proteins monoclonal antibodies recognized by CSF114(Glc), the synthetic probe of Multiple Sclerosis. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 112, ISSN: 1075-2617, doi: 10.1002/psc.1303

[A17]C. Testa, F. Nuti, M. Scrima, A.M. D’Ursi, N. Lubin-Germain, M. Chorev, P. Rovero, A.M. Papini. Stabilization of beta-turn conformation in melanocortin like peptide by click reaction. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 28-29, ISSN: 1075-2617, doi: 10.1002/psc.1301.

[A18]F. Rizzolo, C. Testa, M. Chorev, M. Chelli, P. Rovero, A.M. Papini. Conventional and microwave-assisted SPPS approach: a comparative study of PTHrP(1-34)NH₂ synthesis. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 78-79, ISSN: 1075-2617, doi: 10.1002/psc.1303

[A19]S. Carganico, N. Zanella, G. Sabatino, P. Rovero, M. Chorev, A.M. Papini. A novel diagnostic-prognostic tool for diabetes: UPLC analysis of glycated metabolites. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 169, ISSN: 1075-2617, doi: 10.1002/psc.1303.

[A20]M. Di Pisa, G. Sabatino, M. Chelli, P. Rovero, C. Tiberi, A.M. Papini.Celiac disease: characterization of linear autoantigenic epitopes.JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 176, ISSN: 1075-2617, doi: 10.1002/psc.1303.

[A21]G. Sabatino, M. Di Pisa, M. Chelli, P. Rovero, C. Tiberti, and A. M. Papini. Celiac disease: characterization of amino acids/short peptides finger print for a fast I.V.D. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 176, ISSN: 1075-2617, doi: 10.1002/psc.1303.

[A22]M. Lumini, G. Cane, A. Di Cianni, A.M. Papini, and M. Ginanneschi. A study on the microwaves synthesis of the somatostatin dicarba-analogues. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 78, ISSN: 1075-2617, doi: 10.1002/psc.1303.

[A23]F. Nuti, F. Rizzolo, F. Gori, M. Chelli, P. Rovero, L. Moroder, A.M. Papini. Microwave-assisted solid phase synthesis of collagen peptides. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 79, ISSN: 1075-2617, doi: 10.1002/psc.1303

[A24]F. Gori, B. Mulinacci, L. Massai, F. Lolli, A.M. Papini, P. Rovero. Antigenic probes for autoantibody detection in Multiple Sclerosis: synthetic peptides versus recombinant proteins. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 178, ISSN: 1075-2617, doi: 10.1002/psc.1303.

[A25]S. Pandey, E. Peroni, P. Rovero, F. Lolli, M. Chelli, A. M. D’Ursi and A. M. Papini. Rational design and optimization of newly designed glycopeptide to develop the diagnostic/prognostic assays for Multiple Sclerosis. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 178-179, ISSN: 1075-2617, doi: 10.1002/psc.1303.

[A26]E. Peroni, N. Brodie Linder, C. Alba-Simionesco, A.M. Papini. On-silica peptide probes: innovative in vitro diagnostic devices for detection of antibodies as biomarkers of autoimmune diseases. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 200, ISSN: 1075-2617, doi: 10.1002/psc.1303.

[A27]P. Fantini, M.C. Alcaro, I. Paolini, F. Barbetti, D. Valoriani, A.M. Papini, F. Lolli, P. Rovero, F. Pratesi, P. Migliorini. The 'Chemical Reverse Approach' to identify autoantibodies in Systemic Lupus Erithematosus patients. JOURNAL OF PEPTIDE SCIENCE (2010), vol. 16(S1), p. 175-176, ISSN: 1075-2617, doi: 10.1002/psc.1303.

2012

[A28] C. Testa, D. D'Addona, M. Scrima, A.M. D'Ursi, M.L. Dirain, M. Chorev, P. Rovero, C. Haskell-Luevano, and A.M. Papini. SAR studies of triazolyl-containing cyclopeptides: A defined beta-turn structure increases potency and selectivity to melanocortin receptor subtypes. . JOURNAL OF PEPTIDE SCIENCE (2012), vol. 18(S1), p. S166-S167, ISSN: 1075-2617, doi: 10.1002/psc.2449

[A29]F. Rizzolo, C. Testa, D. Lambardi, M. Chorev, M. Chelli, P. Rovero, A.M. Papini. Fast and Efficient Microwave-Assisted Monitoring of Difficult Peptide Sequences.. JOURNAL OF PEPTIDE SCIENCE (2012), vol. 18(S1), p. 131-132, ISSN: 1075-2617, doi: 10.1002/psc.244

[A30]G. Sabatino, F. Di Pisa, M. Potenza, L. Dei, A.M Papini. UPLC-based amino acid analysis of paintings and statistical analysis of chromatographic profiles for conservation of cultural heritage. JOURNAL OF PEPTIDE SCIENCE (2012), vol. 18(S1), p. S191, ISSN: 1075-2617, doi: 10.1002/psc.2449

[A31]C. Rentier, O. Monasson, F. Nuti, P. Traldi, A. Lapolla, M. Larregola, P. Rovero, A.M. Papini. Synthesis of post-translationally modified peptides for detection of autoantibodies in diabetic patients' sera.. JOURNAL OF PEPTIDE SCIENCE (2012), vol. 18(S1), p. 68-69, ISSN: 1075-2617, doi: 10.1002/psc.2449.

[A32]F. Nuti, F. Real-Fernandez, S. Pandey, J. Hayek, C. De Felice, S. Lavielle, M. Larregola, P. Rovero, A.M. Papini. Autoantibodies to N-glucosylated peptide sequons in Rett syndrome: the first insight to disclose an autoimmune mechanism.. JOURNAL OF PEPTIDE SCIENCE (2012), vol. 18(S1), p. 137, ISSN: 1075-2617, doi: 10.1002/psc.2449.

[A33]C. Rentier, F. Nuti, G. Pacini, P. Rovero, C. Selmi, A.M. Papini. Synthesis of diastereoisomeric modified amino acids derived from lipoic acid for use in solid phase peptide synthesis . JOURNAL OF PEPTIDE SCIENCE (2012), vol. 18(S1), p. S187, ISSN: 1075-2617, doi: 10.1002/psc.2449.

[A34]M. Larregola, G. Pacini, F. Rizzolo, F. Burlina, S. Lavielle, P. Rovero, A.M. Papini. Towards semi-synthetic N-glucosylated MOG to identify aberrantly modified native protein autoantigens in multiple sclerosis.. JOURNAL OF PEPTIDE SCIENCE (2012), vol. 18(S1), p. 101, ISSN: 1075-2617, doi: 10.1002/psc.2449.

[A35]O. Monasson, F. Rizzolo, P. Traldi, A. Lapolla, A.M. Papini. Design and synthesis of new peptide scaffold presenting AGEs as diagnostic tool to monitor biomarkers in diabetes. . JOURNAL OF PEPTIDE SCIENCE (2012), vol. 18(S1), p. S180, ISSN: 1075-2617, doi: 10.1002/psc.2449.

[A36]M. Di Pisa, G. Sabatino, M. Chelli, P. Rovero, A.M. Papini. Synthesis of newly designed peptides for the diagnosis of Celiac Disease.. JOURNAL OF PEPTIDE SCIENCE (2012), vol. 18(S1), p. S188, ISSN: 1075-2617, doi: 10.1002/psc.2449.

[A37]Y. Cao, F. Nuti, G. Rossi, J. Uziel, P. Rovero, A.M. Papini. Synthesis of peptides and sulphated monosaccharides able to identify antibodies in IgM onoclonal gammopathy. JOURNAL OF PEPTIDE SCIENCE (2012), vol. 18(S1), p. S100-S101, ISSN: 1075-2617, doi: 10.1002/psc.2449.

[A38]Y. Cao, F. Nuti, C. Tiberi, J. Uziel, P. Rovero, A.M. Papini. Synthesis of building blocks for the synthesis of glycopeptides to detect anti-ganglioside antibodies in Amyotrophic Lateral Sclerosis. JOURNAL OF PEPTIDE SCIENCE (2012), vol. 18(S1), p. S100, ISSN: 1075-2617, doi: 10.1002/psc.2449.

[A39]A.M. Papini. The mimicry pathway from anti-glycopeptide antibodies to specific protein antigens of immune-mediated neurodegenerative/neuroregressive diseases: the case study of Rett syndrome. JOURNAL OF PEPTIDE SCIENCE (2012), vol. 18(S1), p. S23, ISSN: 1075-2617, doi: 10.1002/psc.2448.

[A40]C. Tiberi, G. Sabatino, M. Di Pisa, P. Rovero, A.M. Papini. SPPS of glucosylated multiple antigen peptides (MAPs) as synthetic probes for detection of autoantibodies in multiple sclerosis patients’ sera. JOURNAL OF PEPTIDE SCIENCE (2012), vol. 18(S1), p. S186, ISSN: 1075-2617, doi: 10.1002/psc.2448.

2014

[A41] C. Rentier, G. Pacini, F. Nuti, C. Selmi, P.M. Battezzati, P. Rovero and A.M. Papini. PEPTIDES OF THE DIHYDROLIPOAMIDE ACETYLTRNSFERASE FOR THE DETECTION OF AUTOANTIBODIES IN AUTOIMMUNE DISEASES. Journal of Peptide Science (2014), Vol. 20(S1). p. S37, Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2686. Abstract YO08 – p. 37.

[A42] M. Larregola, N. Auberger, M. Di Pisa, E. Peroni, G. Chassaing, S. Lavielle, O. Lequin, J.M. Mallet, A.M. Papini. A CONFORMATIONAL STUDY OF NEW GLASER-CYCLIZED PEPTIDES. Journal of Peptide Science (2014), Vol. 20(S1). p. S66, Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2687. Abstract O45, p 66.

[A43] V. Doan, G. Chaume, F. Rizzolo, E. Peroni, A-M. Papini, S. Kara, S. Afonin, E. Strandberg, A. Ulrich, T. Brigaud. SOLID PHASE PEPTIDE SYNTHESIS OF A 19F-LABELED HARZIANIN: AN ANTIMICROBIAL PEPTAIBOL. Journal of Peptide Science (2014), Vol. 20(S1). p. S107-S108, Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract YP38 – p. 107-108.

[A44] D. Petkova, B. Yanachkova, O.Monasson, A-M. Papini, I. Stoineva. SHORT SYNTHETIC PEPTIDES AS INHIBITORS OF ANGIOTENSIN CONVERTIN ENZYME. Journal of Peptide Science (2014), Vol. 20(S1). p. S122. Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract P011 – p. 122.

[A45] C. Rentier, O. Monasson, Z. Ferhat, F. Nuti, G. Sabatino, M. Larregola, E. Peroni and A.M. Papini. COMPARATIVE STUDY OF METHIONINE OXIDATION IN SELECTED PEPTIDE SEQUENCES. Journal of Peptide Science (2014), Vol. 20(S1). p. S128. Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract P022 – p. 128.

[A46] S. Pascarella, F. Melani, L. Giovannelli, A. M. Papini, P. Rovero. MIMICKING SERIN PROTEASE INHIBITOR H1 CHAPERONE FUNCTION IN COLLAGEN BIOSYTNHETIC PATHWAY VIA THE TEMPLATE ASSEMBLED SYNTHETIC PROTEIN APPROACH. Journal of Peptide Science (2014), Vol. 20(S1). p. S173-S174. Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract P100 – p. 173-174.

[A47] D. Uber, J. Makowska, C. Tiberi, A- M. Papini, L. Chmurzyński. SYNTHESIS AND CONFORMATION ALANALYSIS OF PEPTIDES DERIVED FROM HUMAN PIN1 PROTEIN (WW DOMAIN). Journal of Peptide Science (2014), Vol. 20(S1). p. S192-S193. Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract P131 – p. 192-193.

[A48] S. Pascarella, C. Tiberi, L. Giovannelli, L. Pino, A. M. Papini, P. Rovero. DESIGN, SYNTHESIS AND BIOLOGICAL CHARACTERIZATION OF COLLAGEN TURNOVER MODULATORS: DEGRADATION INHIBITOR AND PRODUCTION ENHANCER PEPTIDES. Journal of Peptide Science (2014), Vol. 20(S1). p. S230. Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract P193 – p. 230.

[A49] M. Ieronymaki, M. Larregola, G. Pacini, F. Burlina, S. Lavielle, J. Offer, P. Rovero, and A.M. Papini. SEMI-SYNTHETIC STRATEGY TO OBTAIN ABERRANTLY N-GLUCOSYLATED MYELIN OLIGODENDROCYTE GLYCOPROTEIN: PART I: OPTIMIZATION OF THE SYNTHESIS OF Asn31(Glc)hMOG(1-34). Journal of Peptide Science (2014), Vol. 20(S1). p. S239-S240. Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract P208 – p. 239-240.

[A50] M. Ieronymaki,  E. Peroni, F. Nuti, G. Rossi, P. Rovero, and A.M. Papini. SYNTHETIC STRATEGIES TO CYCLIC PEPTIDE MIMICS OF HNK-1, A POSSIBLE SYNTHETIC ANTIGENIC PROBES FOR CHRONIC DEMYELINATION DISEASE DIAGNOSTICS. Journal of Peptide Science (2014), Vol. 20(S1). p. S240-S241. Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract P209 – p. 240-241.

[A51] C. Rentier, G. Rossi, F. Nuti, A. Lapolla, P. Traldi, P. Rovero and A.M. Papini. KYNURENINE: A POST-TRANSLATIONAL MODIFICATION POSSIBLY INVOLVED IN MULTIPLE SCLEROSIS. Journal of Peptide Science (2014), Vol. 20(S1). p. S245. Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract P217 – p. 245.

[A52] G. Rossi, F. Real-Fernández, F. Panza, F. Pratesi, P. Migliorini, A.M. Papini, P. Rovero. BIOSENSOR CHARACTERIZATION OF THE INTERACTION BETWEEN SYNTHETIC CITRULLINATED PEPTIDES AND AUTOANTIBODIES IN RHEUMATOID ARTHRITIS PATIENTS’ SERA. Journal of Peptide Science (2014), Vol. 20(S1). p. S246-S247. Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract P219 – p. 246-247.

[A53] F. Real-Fernández, G. Rossi, F. Niccheri, M. Ramazzotti, D. Degl’Innocenti, F. Lolli, A.M. Papini and P. Rovero. CHARACTERIZATION OF RECOMBINANT HUMAN DOMAIN ANTIBODIES BY SURFACE PLASMON RESONANCE. Journal of Peptide Science (2014), Vol. 20(S1). p. S247. Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract P220 – p. 247.

[A54] G. Pacini, C. Rentier, F. Nuti, E. Peroni, F. Real Fernàndez, P.M. Battezzati, C. Selmi, P.

Rovero  and A.M. Papini. DETECTION OF AUTOANTIBODIES IN PRIMARY BILIARY CIRRHOSIS USING PEPTIDES OF THE DIHYDROLIPOAMIDE ACETYLTRANSFERASE. Journal of Peptide Science (2014), Vol. 20(S1). p. S247-S248. Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract P221 – p. 247-248.

[A55] G. Pacini, M. Larregola, M. Ieronymaki, A.M. Papini, and P. Rovero. SEMI-SYNTHETIC STRATEGY TO OBTAIN ABERRANTLY N-GLUCOSYLATED MYELIN OLIGODENDROCYTE GLYCOPROTEIN: PART II: EXPRESSION OF RECOMBINANT FRAGMENT hMOG(35-117). Journal of Peptide Science (2014), Vol. 20(S1). p. S269-S270. Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract P255 – p. 269-270.

[A56] E. Peroni, W. Bellagha-Chenchah, F. Real Fernandez , P. Rovero, Z. Ferhat, C. Sella, L. Thouin, C. Amatore, A.M. Papini. INNOVATIVE ELECTROCHEMICAL DIAGNOSTIC DEVICES BASED ON SYNTHETIC CONFORMATIONAL PEPTIDE EPITOPE MIMICS. Journal of Peptide Science (2014), Vol. 20(S1). p. S304-305. Article first published online: 20 AUG 2014. DOI: 10.1002/psc.2688. Abstract P311 – p. 304-305.

22 June, 2018

Peptide organic chemistry

Development of innovative synthetic solid-phase strategies. Microwave assisted peptide and organic synthesis. Bioorganic chemistry of biomolecules: i.e., peptides and proteins. Synthetic & semi-synthetic strategies of co- or post-translationally modified proteins. Unnatural amino acids orthogonally protected for peptide synthesis (i.e., constrained amino acids, glycosyl and lipophilic amino acids, etc.). Peptidomimetics for the development of therapeutic treatments (i.e., cyclisation via click chemistry). Coupling reagents for peptide chemistry (amide and ester bond formation).

Molecular mechanisms of immune-mediated diseases

This project is performed in cooperation with clinicians supporting specimen and clinics of patients. An innovative "Chemical Reverse Approach" has been developed in PeptLab to characterise immune mediated diseases by circulating antibodies and/or metabolites in biological fluids: neurodegenerative and neurodevelopment diseases, i.e. Multiple Sclerosis, Optical Neuromyelitis, Rett Syndrome, Autistic Spectrum Disorders; Rheumatoid Arthritis; Gluten disease;  Primary Biliary Cyrrhosis. Cross-linked peptides, glycoconjugates and all kind of modified peptides (i.e. MAP) and other biomolecules are used as diagnostic, prognostic, and theragnostic tools to follow up disease activity in humans and setting up animal models. For the diagnosis and therapy of autoimmune diseases we investigate the role of co- or post-translational modifications of proteins and peptides (native versus aberrant) by immunochemical studies. The development of innovative diagnostic/prognostic tools by characterisation of biomarkers of disease activity is performed in the context of a strong technology transfer activities sponsored by the Regione Toscana (in cooperation with new start up and spin-off companies, i.e., EspiKem and Apotech). The fundamental research of this project is performed thanks to ANR and Fondation Pierre Gilles de Gennes in cooperation with the Ecole Normale Superieure in Paris.

Recently (January 2017) we established PeptFarm in the MOD&LS lab funded by the Regione Toscana and located at RISE b, Polo Scientifico of Sesto Fiorentino (https://www.unifi.it/upload/sub/csavri/rise_scheda_laboratori.pdf) a joined laboratory between PeptLab and the Industry Fabbrica Italiana Sintetici, F.I.S. SpA to develop large-scale protocols for the GMP synthesis of peptide-based active pharmaceutical ingredients.

Scientific Fields of interest

Peptide and protein organic chemistry. Development of innovative synthetic solid-phase strategies. Microwave assisted peptide synthesis. Bioorganic chemistry of peptides and proteins. Synthetic & semi-synthetic strategies of co- or post-translationally modified proteins. Unnatural amino acids orthogonally protected for peptide synthesis (constrained amino acids, glycosyl and lipophilic amino acids). Coupling reagents for peptide chemistry (amide and ester bond formation).

Synthetic biology. Production of proteins specifically glycosylated, such as glucosylated adhesin protein from Haemophilus influenzae. Expression of cell-surface adhesins including N-Glc, to establish a connection between H. influenzae infection and autoimmune diseases, such as Multiple Sclerosis. We exploited the biosynthetic machinery from the opportunistic pathogen H. influenzae (and the homologous enzymes from A. pleuropneumoniae) to produce a unique set of defined glucosylated adhesin proteins to detect specific and high affinity antibodies.

Industrial applications

In vitro Diagnostics and peptide biomarkers. Autoimmune diseases. Molecular mechanisms of immune-mediated autoimmune diseases. Cross-reaction with infectious diseases. Glycoconjugates as diagnostic and prognostic tools for human, animal, and plant diseases. Diagnosis and therapy of autoimmune diseases: role of co- or post-translational modifications of myelin proteins and peptides for immunological studies on multiple sclerosis for the development of diagnostic/prognostic tools, innovative immunotherapies and characterisation of biomarkers of disease activity. Apheresis technologies. In vivo Diagnostics and imaging techniques. DOTA peptide analogues for cancer pre-targeting diagnosis & therapy. FIV peptides for the development of an anti-retroviral therapy for felines. Cultural heritage. Peptide-based immunoassays for characterization of glues, in particular collagen. Peptide Nutraceuticals and cosmeceutics. Spiruline. Fish feed. Peptides involved in collagen turnover. Development of processes for large scale solid-phase peptide synthesis. GMP production of active peptides as pharmaceutical ingredients. MW-technology. Peptide materials.

Who is interested to follow one of my lessons in Bioorganic Chemistry please copy this link into your browser

https://cloud.cla.unifi.it/owncloud/index.php/s/BKTPrYW6nS3SFTD

Chi fosse interessato a effettuare un'esperienza all'estero nell'ambito del suo ciclo di studi o anche successivamente, offro supporto in qualità di delegato per il programma Erasmus (LLP e Placement) per la Chimica e in qualità di delegato del Corso di laurea in Chimica per l'organizzazione di tirocini curriculari e extra-curriculari.

Contattemi via e-mail: annamaria.papini@unifi.it

Education and Scientific Graduation

1977-1983: Italian “Laurea” in Chemistry, Curriculum Organic Chemistry & Chemical Biology of the University of Florence (Italy). Title of the “Laurea” thesis: Regioselective functionalisation of cyclic ethers and thioethers: synthesis of bifunctional derivatives via IVB organometallic compounds”.

1985-1989: International Ph.D. in Chemical Biology of the Italian Ministry of Education Title of the PhD thesis: . 1985-1986 Department of Biochemistry, University of Sherbrooke, Québec, Mentor Prof. Dr. Gilles Dupuis; 1986-1988 Dept. of Organic Chemistry, University of Florence, Mentor: Prof. Gianfranco. Rapi and 1988-1989 Department of Peptide Chemistry, Max Planck Institute für Biochemie, Martinsried Bei Muenchen, Mentor Prof. Dr. Luis Moroder. Title of the PhD thesis: “Synthesis of peptides for chemical, bio-pharmacological and immunological studies”.

1990 Specialisation in Dermatochemistry, Dermatological Department of the Florence University Hospital. Supervisor Pr. M.D. E. Panconesi.

2013-2019, confirmed for 2018-2024: Habilitation to the function of Full Professor of Organic Chemistry of the Italian Universities.

Since 2001: Habilitation to the function of Full Professor of Organic Chemistry of the French Universities.

Curriculum vitae Anna Maria Papini, PhD

Who is interested to follow one of my lessons in Bioorganic Chemistry please copy this link into your browser

https://cloud.cla.unifi.it/owncloud/index.php/s/BKTPrYW6nS3SFTD

or Tape record of the talk: 

Theo Murphy International Scientific Discussion meeting at The Royal Society “Self-assembled peptides: from nanostructure to bioactivity” Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell, Buckinghamshire, MK16 9JJ (UK), October 24-25, 2016. Plenary Lecture October 25, 2016. Title: Autoimmunity and neurodegeneration: the mimicry pathway from aberrant N-glucosylated peptides to specific protein antigens.

http://downloads.royalsociety.org/events/2016/10/self-assembled-peptides/Papini.mp3

Education and Scientific Graduation

1977-1983: Italian “Laurea” in Chemistry, Curriculum Organic Chemistry & Chemical Biology of the University of Florence (Italy). Title of the “Laurea” thesis: Regioselective functionalisation of cyclic ethers and thioethers: synthesis of bifunctional derivatives via IVB organometallic compounds”.

1985-1989: International Ph.D. in Chemical Biology of the Italian Ministry of Education Title of the PhD thesis: . 1985-1986 Department of Biochemistry, University of Sherbrooke, Québec, Mentor Prof. Dr. Gilles Dupuis; 1986-1988 Dept. of Organic Chemistry, University of Florence, Mentor: Prof. Gianfranco. Rapi and 1988-1989 Department of Peptide Chemistry, Max Planck Institute für Biochemie, Martinsried Bei Muenchen, Mentor Prof. Dr. Luis Moroder. Title of the PhD thesis: “Synthesis of peptides for chemical, bio-pharmacological and immunological studies”.

1990 Specialisation in Dermatochemistry, Dermatological Department of the Florence University Hospital. Supervisor Pr. M.D. E. Panconesi.

2013-2019 and renewed for 2018-2024: Habilitation to the function of Full Professor of Organic Chemistry of the Italian Universities.

Since 2001: Habilitation to the function of Full Professor of Organic Chemistry of the French Universities.

Employment History

Since March 1, 2020: Appointed Full Professor (professore ordinario) of Organic Chemistry at the Department of Chemistry “Ugo Schiff” of the University of Florence (Italy). (s.c. 03/C1 Chimica Organica, s.s.d. CHIM/06 Chimica Organica, Call D.R. n. 473, 17 April 2019 ex art. 18, c.1, Law 240/10; approval of the acts D.R. n. 1471, 20 November 2019, Deliberation 29 November 2019 of the Council of the Dept. of Chemistry, deliberation of the Consiglio di Amministrazione 31 January 2020).

Since 2017: Associated to the CNR Institute of Cristallography (Director Michele Saviano, Istituto CNR di Cristallografia, www.ic.cnr.it/ic4/en/).

Since 2004 to date: Co-founder and head of the Interdepartmental Laboratory of Peptide & Protein Chemistry & Biology, Polo Scientifico of the University of Florence associating the Departments of Chemistry, Pharmaceutical Sciences & Neurosciences of the University of Florence.

2010-2019: Founder and coordinator of the French-Italian Laboratory of Peptide & Protein Chemistry & Biology associating the Departments of Chemistry, Pharmaceutical Sciences & Neurosciences of the University of Florence (Italy) and the Laboratory of Chemical Biology of the Université Paris-Seine, Cergy-Pontoise (France).

Since 2013 Founder and Director of the Platform PeptLab@UCP of the Université Paris-Seine, Cergy-Pontoise (France), since 2020 CY Cergy Paris Université.

2001: Awarded Full Professor for the Chair of Organic Chemistry of the Claude Bernard University Lyon 1 (France). Waiver.

November 2002-February 2020: Associate Professor and Chair of Organic Chemistry of the University of Florence.

2001-2002: Researcher at the Department of Organic Chemistry, University of Florence.

1991-2001: “Tecnico Laureato” at the Department of Organic Chemistry of the University of Florence, associated to the Chair of Chemistry for the Medical School.

Teaching activities at the School of Mathematical, Physical, and Natural Sciences, Department of Chemistry, University of Florence

Since 2019-2020: English Master Course in Advanced Molecular Sciences: Course Advanced synthetic methods (6CFU/ECTS).

Since 2010 to date: “Laurea Magistrale” in Chemical Sciences: curriculum in Chemistry of Biological Molecules: Course Chemistry of Biomolecules (6 CFU/ECTS); curriculum in Synthesis and reactivity of organic molecules, Course Bioorganic Chemistry (6 CFU/ECTS).

2002-2007: “Laurea triennale” in Chemistry (6 CFU/ECTS): Course Laboratory of Organic Chemistry I.

2007-2009: “Laurea Specialistica” in Chemistry of Biological Molecules: Course Bioorganic Chemistry & Laboratory of Bioorganic Chemistry (6 CFU/ECTS).

Scientific contributions

1. www.peptlab.eu

A.M. Papini contributed with 260 scientific publications: 152 peer-reviewed articles in scientific journals (of which reviews, editorials), 108 peer-reviewed articles in books, 11 International Patents.

Communication of the scientific activity

2000-2020: invited to present 127 lectures: 100 lectures in International Symposia (keynotes, invited and plenary), Universities and Research Centres (EU, USA, Canada, Australia, Israel, Japan, China) and 27 lectures aimed to technology transfer in the global space of R&D. 1997-2020: 59 oral & 251 poster communications were selected in international symposia and presented by her students or co-workers or personally. 

Academic Roles and Responsabilities

Since 2013 Delegate of the International Affairs of the School of Sciences of the Uuniversity of Florence (Italy) and Responsible of the Erasmus + Exchanges Programmes for Study and Traineeship of the students incoming and outcoming (ca. 300 students/year) of the School of Sciences (Physics, Chemistry, Mathematics, Informatics, Biological and Natural Sciences, Earth sciences, Optics, Biotechnology, Cultural Heritage). Responsible of the Erasmus + Exchanges Programmes for Staff Teaching and Administrative Mobility.

Since 2005 Coordinator of the Erasmus Programme of Chemistry of the Faculty of Sciences of the University of Florence (Italy). Responsible of Erasmus Exchanges Programme for Study and Traineeship of the students of Chemistry.

2012 Member of the Committee for the selection of TFA A059 (Educational Trainings for teachers of chemistry in the secondary school).

2011 Representative of the Department of Chemistry of the University of Florence in the Pole of innovation for life sciences (“Polo d’Innovazione per le Scienze della Vita”.

Since 2010 Member of the Board of the PhD School in Chemical Sciences of the University of Florence.

2010-2014 Delegate of the Faculty of Sciences in the Board of the Foreign Language Centre (CLA - Centro Linguistico d’Ateneo) of the University of Florence.

2006-2016 Vice President and Delegate for Chemistry in the Board of OpenLab (Educational organisation of the Faculty of Sciences of the University of Florence.

2006-2009 Member of the Board of the PhD School in Non linear systems and complex dynamics of the University of Florence.

Awards for the scientific activity

2019-2020: Rita Levi Montalcini Award for Italian-Israeli Cooperation for the project “Role of sugars in immune-mediated diseases”. 4-Month scientific visits in Israel: 22-24 December 2019, Azrieli Faculty of Medicine, Bar Ilan University, Safed (Prof. Nir Quit). 4-11 January 2020, Department of Immunology, Weizmann Institute of Sciences, Rehovot (Dr. Rina Aharoni and Prof. Ruth Arnon). 12-16 February 2020, Department of Immunology, Weizmann Institute of Sciences, Rehovot (Dr. Rina Aharoni) 17-24 February 2020, Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem (Dr. Mattan Hurevich, Prof. Assaf Friedler, and Prof. Shlomo Yitzchaik.

2009-2014: Chaire d’excellence of the French Agence Nationale de la Recherche (unique of chemistry out of 16 attributed in 2009), ANR-09-CEXC-013-01, Project PepKit : Development of peptide-based-diagnostic kits for autoimmune diseases.

2008: Leonidas Zervas Award for outstanding contribution to peptide chemistry, 30th EPS, Helsinki (Finland), August 31, 2008.

2008: 1st D. Theodoropoulos Memorial Lecture Award for outstanding achievements in Peptide Sciences, 6th Hellenic Forum on Bioactive Peptides, Patras (Greece), May 18, 2008.

2006: Best Poster Award Lucio Senatore, XXII Congresso Nazionale della Società Chimica Italiana [V. Volkov, F. Nuti, Y.Takaoka, R. Chelli, A.M. Papini, and R. Righini. Structure and bonding of water molecules in the polar region of phospholipid membrane investigated by two-dimensional IR spectroscopy and MD computer simulation. XXII Congresso Nazionale della Società Chimica Italiana, Firenze, September 10-15, 2006, Abstract FIS-P-135] attributed to the work performed with the Postdoc student F. Nuti and of the coworker R. Chelli.

2005: Bert Schram Price. Honorable Mention, 19th American Peptide Symposium, San Diego, California, USA [B. Mulinacci, C. Breithaupt, P.P. Pal, N. Budisa, M. Pazzagli, B. Mazzanti, P. Rovero, L. Moroder, and A.M. Papini. Cross-reactivity studies of rMOGED with the synthetic putative autoantigen CSF114(Glc) and [N31(Glc)]hMOG(30-50) in Multiple Sclerosis patients’ sera. 19th American Peptide Symposium (San Diego, CA, USA), June 18-24, 2005, LY 03, Abstract p. 484] attributed to the work performed with the PhD student B. Mulinacci.

2005: Best Poster Award Glycoconjugates “Glyco XVIII”, Florence, Italy [F. Nuti, I. Paolini, B.Mulinacci, M. Pazzagli, F. Lolli, M. Chelli, P. Rovero, and A.M. Papini. Sugar-scan of CSF114(Glc) for autoantibody recognition in Multiple Sclerosis. XVIII International Symposium on Glycoconjugates. Glyco XVIII”, Firenze, September 4-9, 2005, Abstract P057, Glycoconjugate J., 2005, 22(4–6), 254] attributed to the work performed with the PhD student F. Nuti.

1999: Bruce W. Erickson Award for outstanding achievement in peptide sciences, 16th American Peptide Symposium, Minneapolis, Minnesota, USA [E. Nardi, S. Mazzucco, S. Matà, M. Chelli, B. Mazzanti, E. Traggiai, M. Ginanneschi, F. Pinto, L. Massacesi, M. Vergelli, H. Kalbacher, F. Lolli and A.M. Papini. Influence of different N-linked glycosyl moiety at position 31 of hMOG(30-50) on anti-MOG antibody recognition in multiple sclerosis patients. 16th American Peptide Symposium, Minneapolis (Minnesota, USA), June 26-July 1, 1999, Abstract P148] attributed to the work performed with the PhD student E. Nardi.

Awards for the technology transfer activity

2009: Vespucci Award for founding the startup Toscana Biomarkers.

2008: Frost & Sullivan Excellence in Research Award in the European autoimmune disease diagnostics market presented to AMP for the startup Toscana Biomarkers.

2006: Start-Cup for business plan of the start-up Toscana Biomarkers.

2004: Vespucci Award, Research & Ethical Innovation to AMP as inventor of PCT (2003) WO 03000733 A2.

Technology transfer activity

2017-2020 Founder and Scientific Coordinator of PeptFarm “Laboratorio congiunto Università di Firenze – Impresa” joining PeptLab and Fabbrica Italiana Sintetici, F.I.S. Italy to develop large-scale synthesis of active pharmaceutical peptide drugs.

2016: Founder of the spin-off company Apotech for R&D of peptide-based cosmeceutics.

Since 2014 Member of the Scientific Advisory Board of Regulaxis (www.regulaxis.com)

2007-2015: Founder & Chief Scientific Officer of the startup Toscana Biomarkers

Since 2003: Founder and member of the Board of EspiKem, 1st spinoff of the University of Florence

Recent Research Funding

2020-2024: “Mother and Infant dyads: Lowering the impact of endocrine disrupting Chemicals in milk for a Healthy Life” LIFE18 ENV/IT/000460 “life MILCH”. Total cost of the project for the University of Florence € 711.028 (UNIFI will contribute with € 326.150 of own financial resources and will receive from the coordinating beneficiary a maximum amount of € 384.878).

2017-2019: “Regione Toscana POR CReO FESR 2014-2020”. EcoReLabel: Ecological removable and recyclable labels. 303.000,00 Euro

2010-2012: “Regione Toscana POR CReO FESR 2007-2013”. MARK: Identification of diagnostic biomarkers of autoimmune diseases.450.000,00 Euro.

2005-2011: “Fondazione Cassa di Risparmio di Firenze”. Molecular characterisation of peptide-protein interaction in autoimmune diseases. 1.500.000 Euro for PeptLab at University of Florence.

2005-2007: International FIRB- Italian Ministry of University & Research and Harvard Medical School. 350.000,00 Euro.

2002-2003, 2005-2006, 2008-2009: PRIN-Italian Ministry of University & Research. Design, synthesis & immunological characterisation of modified peptides to follow up autoimmune diseases. 700.000,00 Euro.

2009-2014: “Chaire d’Excellence” (ANR-09-CEXC-013-01). PepKit: Development of peptide-based-diagnostic kits for autoimmune diseases. 999.998,00 Euro for the PeptLab@UCP platform.

2016-2018 Lauréate MRSEI-ANR Edition 2015, Project REDIPOC to organize and submit a FET-OPEN project by January 2017 for a Reliable Diagnostic Point Of Care Network, 20.000 Euro.

2013-2016 PhD grant CIFRE in cooperation with REGULAXIS, 90.000 Euro.

2015-2018 BIRAC, Indo-French Challenge-oriented Call for proposals 2014 : AMIR-PepKit IVD, R&D of a peptide-based-diagnostic kit for for an early detection of a fatal immune response in acute myocardial infarction patients. 50.000 Euro.

2011-2013: “Fondation Pierre-Gilles de Gennes”. Immune-mediated diseases: Glycopeptidomic-based diagnostics to follow-up disease activity. 2 post-doctoral fellows + 90.000 Euro for materials.

Panel Member of international evaluation committees attended personally

2020: Panel member (representing the CNU Section 32) of the of the French High Council for Evaluation of Research and Higher Education (HCERES) for the evaluation committee Group A of the Unit Institut de Biomolécules Max Mousseron, Montpellier (February 25-28, 2020).

2012-2019: Panel Member for ERC Advanced Grant evaluation PE5 – Synthetic chemistry and materials, Brussels (attended 4 panels, 2 meetings every two years).

2018 & 2019: Expert Evaluator by REA for H2020-MSCA-IF.

2019-2021: Nominated as 1 out of 8 members of the External Scientific Advisory Board of The Institute for Advanced Chemistry of Catalonia (IQAC), belonging to the Spanish National Research Council (CSIC), and devoted to research of excellence in Chemical Sciences as a leading scientist in peptide chemistry and the application of peptides in different fields (first Meeting in Barcelona, Catalonia 25-26 November 2019)

2020: Member of the expert panel and acting as Leader of the expert panel for the Research Council of Lithuania for the “Distinguished Professor Programme”. Evaluation of 12 projects in the field of Natural, Technical, Medical and Agricultural Sciences (01 February-2020-05 March 2020).

2019: Member of the panel to evaluate the Erasmus Mundus joint Master Degree SERP+ (for Qualifications in the European Higher Education Area - FQ-EHEA), a two-year programme in Surface, Electro, Radiation, and Photo-Chemistry with elements of Management, Business, Innovation and Valorisation, Communication and Patent law (Université Paris-Sud, Universidade de Porto, Università degli studi di Genova, Uniwersytet im. Adama Mickiewicza). Poznan (Poland), June 1-3, 2019.

2019: Member of the expert commission of the Research Council of Lithuania for the Competitive Funding of Research and Dissemination Projects (evaluation of 27 projects). Two-stage evaluation process: 1st stage individual expert assessment of the proposal remotely (by March 17, 2019); 2^nd stage participation at the panel’s assessment followed by the summary evaluation on March 22, 2019, 9:00-18:00, Research Council of Lithuania in Vilnius (Gedimino av.3, Room 212), Lithuania.

2019: Nominated member of the Scientific Evaluation Committee N° 44 " Biochemistry of living organisms " for the French Agence Nationale de la Recherche. ChâteauForm’ République 8 Bis Rue De La Fontaine Au Roi, 75011 – Paris (France), January 14-15, 2019 and 17-18 June 2019.

12-14 November 2018: Member of the training committee for the implementation of the European Approach to Quality Assurance of Erasmus Mundus Joint Master Degrees to evaluate in 2019 the Joint Master SERP+ Programme (Surface, Electro, Radiation, and Photo-Chemistry) based on the consortium composed of Université Paris-Sud, Università degli studi di Genova, Universidade do Porto, Uniwersytet im. Adama Mickiewicza University in Poznan (in Poznan on June-July 2019).

24-29 September 2018: Panel member as expert of bioorganic chemistry and chemical biology for assessment of research and development of the universities and research institutions of Lithuania in the field of physical sciences.

26-27 July 2018: Panel member of the Foundation for Polish Science to select the winners of the First Team programme, edition 5/2018, Warsaw (Poland).

6-7 December 2017: Vice-president of the French High Council for Evaluation of Research and Higher Education (HCERES) evaluation committee Group D of the Unit Molecules of Communication and Adaptation of Microorganisms (MCAM) UMR 7245 CNRS Muséum National d’Histoire Naturelle (MNHN).

2016-2019 Elected member of the “Conseil Nationale des Universités” - CNU (France) to deliberate habilitations and promotions of the French University researchers and professors.

June 2016: Member of the evaluation panel for Promotion of Research and Development Programmes Implementation for the Ministry of Education, Science, and Sport, Republic of Slovenia.

February 2011: Member of the AERES Committee for evaluation of the ICM of the University of Reims.

2011-2012 Member of the Evaluation Committee of research projects submitted to the Fondation de la Recherche Médicale, France.

March 2010: Member of the AERES Committee for evaluation of iBiTecc-S Equipe SIMOPRO (CEA, Saclay).

Since 2010 Member of the Council of “Ordine dei Chimici della Toscana” (Society of Chemists in Tuscany).

Remote Referee of international evaluation committees

2019: Expert member for the European Science Foundation

2017 Expert member for the German-Israeli Foundation (GIF) for Scientific Research and Development to evaluate projects presented at the GIF Regular Program.

2016 External Member of an “Ad Hoc Committee” for promotion review at The Scripps Research Institute (TSRI) of candidates to the rank of Associate Professor with Tenure.

2016 Appointed external evaluator for research projects submitted to the United States – Israel Binational Science Foundation (BSF).

2016 Appointed External evaluator of candidates for Faculty Positions in the subject field: “Organic Chemistry with emphasis on Chemistry” at the University of Patras (Greece).

2015-2016 Appointed Reviewer for research projects submitted to the executive government agency of the Polish National Science Centre (Narodowe Centrum Nauki - NCN; http://www.ncn.gov.pl).

2014 Appointed reviewer by “Vienna Science and Technology Fund (VSTF, Austria)” to evaluate proposals submitted to the Vienna Research Groups for Young Investigators call in the field of “Life Sciences”.

2014 Appointed Reviewer by the National Science Centre in Poland (Narodowe Centrum Nauki - NCN; http://www.ncn.gov.pl) to evaluate projects in the Funding scheme PRELUDIUM.

2011-2013 Appointed reviewer by the “Association Nationale Recherche et Technologie (ANRT, Paris, France) to evaluate proposals CIFRE (Conventions Industrielles de Formation par la Recherche) to fund PhD 50% in industrial environments.

Activity as delegate, panel member and evaluator in Italy

2012-2017 Referee for the Evaluation of the quality of the research of the Italian Universities (VqR )

2012 Member of the Committee for the selection of TFA A059 (Educational Trainings for teachers of chemistry in the secondary school)

2011-2015 Representative of the Department of Chemistry of the University of Florence in the Pole of innovation for life sciences (“Polo d’Innovazione per le Scienze della Vita”.

2010-2014 Delegate of the Faculty of Sciences in the Board of the Foreign Language Centre (CLA - Centro Linguistico d’Ateneo) of the University of Florence.

2010-2020 Member of the Council of “Ordine dei Chimici della Toscana” (Society of Chemists in Tuscany).

2006-2016 Vice President and Delegate for Chemistry in the Board of OpenLab (Educational organisation of the Faculty of Sciences of the University of Florence.

Since 2010 Member of the Board of the PhD School in Chemical Sciences of the University of Florence.

2006-2009 Member of the Board of the PhD School in Non linear systems and complex dynamics of the University of Florence.

2012-2017 Referee for the Evaluation of the quality of the research of the Italian Universities (VqR )

Organisation of international Symposia

2022: Elected in 2016 by the General Assembly of the European Peptide Society Chairperson of the 14th International Peptide Symposium and 37th European Peptide Symposium that will be held in Florence (Italy), 28 August-2 September 2022.

2019: Chairperson of the “Giornata scientifica della Società Italiana Peptidi dedicata ai Soci Giovani, Premio scientifico Vittorio Erspamer. September 21, 2019, Polo Didattico Morgagni, University of Florence, Viale Morgagni 44, Firenze (Italy)

2019: Chairperson with Fernando Albericio of the International Oligonucleotides and Peptides Conference, Track Peptides, Ramada Plaza Hotel, Milano (Italy), September 17-18, 2019.

2019: Chairperson Session III: Peptide Nutraceutics and Cosmeceutics and Session IV: Peptide Engineering and Smart Materials, CIS 2019 - Chemistry meets Industry and Society, Società Chimica Italiana, WS3 – Smart Peptide Chemistry for next generation industry in a sustainable society, Grand Hotel Salerno, Salerno (Italy), August 28-30, 2019.

2016: Chairperson of the 2016 GRC: Chemistry & Biology of Peptides: Crossing Barriers by Peptide Science for Health and Wellness, with Prof. Dr. P. Dawson, Ventura, CA (USA), 21-26/02/2016

2014: Vice-chair of the GRC: Chemistry & Biology of Peptides: Peptide Science in the Era of Synthetic Biology, Ventura, CA (USA), 23-28/02/2014.

2016: Chairperson of 1st Mass Spectrometry Peptide Day, Convento di Sant’Apollonia, Firenze, 10-12 February 2016 (http://www.spettrometriadimassa.it/Congressi/1MS-PeptideDay/)

2014: Chairperson of the International Symposium Peptides in Paris PIPS 2014 and Training Course 5-10 October 2014. Co-editor of the special issue in Biopolymers Peptide Science together with S. Lavielle (UPMC, Paris) and W.D. Lubell (Université de Montreal).

2014: Responsible of the thematic semester “Peptides & Proteins Molecules of Life. Université de Cergy Pontoise (France) as final event of the Chaire d’Excellence 2009-2014.

2011: Chair of the Symposium "PEPTIDES AND PROTEINS IN THE NEW MILLENNIUM" organised in honour of the Doctorate Honoris Causa attributed from the Université de Cergy-Pontoise to Prof. Luis Moroder in Neuville-sur-Oise (France), 5-6 October, 2011.

2011: Microwave-Assisted Organic Peptie Synthesis (MAOPS2), Chiostro del Maglio, Firenze (Italy), 26-28 April 2011.

2010: 1ST ITALY-AUSTRALIA PEPTIDE SYMPOSIUM ON BIOMOLECULES FOR DIAGNOSTICS & THERAPEUTICS, Satellite of 31st European Peptide Symposium, Monash University, Prato (Italy), 10-12 September, 2010.

2007: EUROCOMBI4, 1ST INTERNATIONAL SYMPOSIUM ON COMBINATORIAL SCIENCES IN BIOLOGY, CHEMISTRY, CATALYSTS AND MATERIALS, Chiostro del Maglio, Firenze (Italy), 15-18 July, 2007.

2006: INTERNATIONAL TRAINING COURSE ON MASS SPECTROMETRY & HIGH PERFORMANCE LIQUID CHROMATOGRAPHY OF PROTEINS (sponsored by UNESCO), Polo Scientifico, Università di Firenze, 1-12 May 2006.

2003: 1ST PRACTICAL TRAINING COURSE: INNOVATIVE COMBINATORIAL APPROACHES AND TECHNOLOGIES (sponsored by European Society of Combinatorial Sciences,) Polo Scientifico, Università di Firenze, 9-11 April, 2003.

Member of scientific committees of international symposia

2020: Member of the Scientific Advisory Board of the 12th International Peptide Symposium and 36^th European Peptide Symposium, Sitges (Spain) August 30-September4, 2020.

2018: Member of the Scientific Committee of the 16th Naples Workshop on Bioactive Peptides, Naples (Italy) June 7-9, 2018.

2017: Nominee member of the Advisory Committee of the American Peptide Symposium 2019, Monterey, CA, USA, June 22-27, 2019.

2017: Nominee member of the Organising Committee of the European Chemistry Conference, Roma (Italy) June 11-13, 2018.

2016: 34th European Peptide Symposium, Leipzig (Germany); 2014: 33rd European Peptide Symposium, Sofia (Bulgaria), 2010: 31st European Peptide Symposium, Copenhagen (Denmark).

2009: SCS-09 2nd International Symposium on Combinatorial Sciences in Biology, Chemistry, Catalysts and Materials, Bejing (China).

2002 and 2004: 2nd, 3rd and 5th Medicinal Chemistry Conference: Drug discovery and Design, University of Patras (Greece).

Member of international evaluation and selection committees of PhD and habilitation exams

August-September 2018 Member of the selection committee of the 34thPhD Course in Chemical Sciences of the University of Florence (Italy).

2010, 2012 & 2013 Referee at Ecole Doctorale Université Pierre et Marie Curie, Paris (France)

2010 Referee at Ecole Doctorale Université Montpellier 2

2009 Referee at Ecole Doctorale Université de Bourgogne

2008, 2010 & 2011 Referee at Ecole Doctorale Université de Strasbourg

2011, 2016 & 2016 Referee at Ecole Doctorale Université Paris-Sud (France)

2012 Referee at PhD School University of Montreal (Canada).

Referee of “Habilitations à diriger les recherches” (HDR)

2008 University of Strasbourg (France)

2011 Université Pierre et Marie Curie, Paris (France).

Activities as Visiting Professor/Scientist

2020 Staff Teaching Mobility, Université de Rouen (8h teaching)

2019 Erasmus Teaching Mobility at the University of Wroclaw (Poland) (13h teaching – 1 week)

2018 Erasmus Teaching Mobility at the University of Wroclaw (Poland)

2016 Erasmus Teaching Mobility at the University of Wroclaw (Poland)

2010 Erasmus Teaching Mobility at the University of Bolu (Turkey)

2010 Erasmus Teaching Mobility at the University of Balikesir (Turkey)

2010 Erasmus Teaching Mobility at the University of Patras (Greece)

2010 Erasmus Teaching Mobility at the University of Gdansk (Poland)

2008 Invited Professor at the Université de Cergy-Pontoise (France)

2008 Invited Professor at the Université de Bourgogne, Dijon (France)

2005 Invited Professor of Organic Chemistry at the Université de Bourgogne, Dijon (France)

1999 Visiting Scientist at the Medizinisch Naturwissenschaftlichens Forschungs Zentrum, University of Tuebingen (Germany)

1998-1999 Invited Professor of Organic Chemistry, U.F.R. Sciences et Techniques, Neuville sur Oise, Université de Cergy-Pontoise (France)

Innovative Teaching and Dissemination Activities in Italy

2020: Panel member of the evaluation committee of the finalists of FameLab 2020: “Talent della scienza, la competizione internazionale di comunicazione scientifica per giovani ricercatori e studenti universitari” OpenLab, Psiquadro, and British Council Italy (the first 2 will partecipate 17-19 aprile 2020 at masterclass in comunicazione della scienza in vista della finale nazionale di Trieste, 4 maggio 2020 e della finale internazionale di Cheltenham, nel Regno Unito il 4-5 giugno 2020.

2010-2012 Director of the “Corso di Specializzazione per la Professione di Chimico”, Faculty of Sciences of the University of Florence in cooperation with Ordine dei Chimici della Toscana.

2010 and 2011 Organiser of the Course “Rischio Chimico” for VVFF (Vigili del Fuoco) in the Regione Toscana in cooperation with OpenLab and Ordine dei Chimici della Toscana

2010 Organiser of the Course “Mass Spectrometry” for VVFF (Vigili del Fuoco) in the Regione Toscana in cooperation with OpenLab and Ordine dei Chimici della Toscana.

2002-2003 Member of the Board and teaching activity in the Master 2nd level “Innovative Synthetic Methodologies” of the Faculty of Sciences of the University of Florence.

2002 Member of the Organising Board of the Open day of the Department of Chemistry XII Week of Scientific Culture in Tuscany.

Since 2001 Organiser of Chemistry Activities for OpenLab – Dissemination of Science at the Polo Scientifico e Tecnologico of the University of Florence for students from 3 to 18 years old of the Schools in Tuscany.

1986-1990 Trainer of Chemistry for Teachers of Primary Schools in the Project IRRSAE in Tuscany.

Supervisor of diploma/master/bachelor and PhD theses

Supervisor of 26 PhD theses in Chemical Sciences: 22 finalised and 4 ongoing, 54 finalised master theses in Chemical Sciences, supervisor of 27 Bachelor students of which 1 ongoing. Tutor of Erasmus students: 26 Traineeship for periods going from 4 months till 1 year.

Snap-shot of the group (as of March 2020, IT & FR)

4 PhDs; 5 Post-docs; 1 Senior Researcher; 3 Associate Professors (1 IT and 2FR); 5 Master students; 6 Bachelor students; 4 Erasmus traineeship students. Since March 2017 Dr Claudia Bello was accepted to join PeptLab at the University of Florence with the 3-year tenure track position RTDb as recipient of the Italian Rita Levi Montalcini 2014 Programme funded by the Italian Ministry of Education for reintegration of Italian young scientists from abroad and since March 1, 2020 she was promoted to associate professor with a permanent position.

Editorial Advisory Board Member

Since 2005 Editor-for-Europe of Protein & Peptide Letters, Bentham Science Publishers Ltd.

Since 2004 Current Drug Delivery, Bentham Science Publishers Ltd. Since 2005 International Journal of Peptide Research and Therapeutics.

Since 2009 Member of the Editorial Advisory Board of Journal of Peptide Science, Wiley Publisher.

Since 2013 Member of the Editorial Advisory Board of Current Protein & Peptide Science, Bentham Science Publishers Ltd.

Since 2003 Member of the Editorial Advisory Board of International Journal of Peptide Research and Therapeutics, Springer

Since 2017 Member of the Editorial Board di Biosensors – Open Access Jounal MDPI (ISSN 2079-6374; CODEN: BIOSHU

Since 2018 Review Editor of Frontiers in Chemistry – Chemical Biology Open access publisher

Since 2018: Associate Editor of Current Peptide and Protein Sciences, Bentham Science Publishers Ltd.

2007-2016 Member of the Editorial Board of Chemistry Today, Editor Teknoscienze

Member of the board of scientific societies

2019-2025: Elected Councilor of the American Peptide Society.

2011-2020: Treasurer and member of the Board of the European Peptide Society.

2017-2020: Nominee Member of the Scientific Committee of the Italian Peptide Society

2004-2008: Nominee Member of the Scientific Affairs Committee of the European Peptide Society.

2000-2013: Nominee academic representative for Italy in the Board of the Society of Combinatorial Chemistry.

Scientific Societies Membership

Since 1988: Charter Member of the American Peptide Society.

Since 1988: Member of the European Peptide Society. Since 1988: Member of the Federation of American Societies for Experimental Biology.

Since 2000: Member of the Society of Combinatorial Sciences.

Since 1993: Charter Member of the Division of Chemistry of Biological Systems of the Italian Society of Chemistry.

Since 2016: Founder and member of the Italian Peptide Society

Scientific Fields of interest

Peptide and protein organic chemistry. Development of innovative synthetic solid-phase strategies. Microwave assisted peptide synthesis. Bioorganic chemistry of peptides and proteins. Synthetic & semi-synthetic strategies of co- or post-translationally modified proteins. Unnatural amino acids orthogonally protected for peptide synthesis (constrained amino acids, glycosyl and lipophilic amino acids). Coupling reagents for peptide chemistry (amide and ester bond formation).

Industrial applications

In vitro Diagnostics and peptide biomarkers. Autoimmune diseases. Molecular mechanisms of immune-mediated autoimmune diseases. Cross-reaction with infectious diseases. Glycoconjugates as diagnostic and prognostic tools for human, animal, and plant diseases. Diagnosis and therapy of autoimmune diseases: role of co- or post-translational modifications of myelin proteins and peptides for immunological studies on multiple sclerosis for the development of diagnostic/prognostic tools, innovative immunotherapies and characterisation of biomarkers of disease activity. Apheresis technologies. In vivo Diagnostics and imaging techniques. DOTA peptide analogues for cancer pre-targeting diagnosis & therapy. FIV peptides for the development of an anti-retroviral therapy for felines. Cultural heritage. Peptide-based immunoassays for characterization of glues, in particular collagen. Peptide Nutraceuticals and cosmeceutics. Spiruline. Fish feed. Peptides involved in collagen turnover. Development of processes for large scale solid-phase peptide synthesis. GMP production of active peptides as pharmaceutical ingredients. MW-technology. Peptide materials.

Anna Maria Papini was born in Firenze (Italy) on February 2, 1959. Married with 2 daughters Giulia (born in 1991) and Elena (born in 1996). French and Italian nationality. Bilingual: French and Italian mother tongues. Language skills: English and German.

 March 5, 2020

Scientific contributions

A.M. Papini contributed with 260 scientific publications: 152 peer-reviewed articles in scientific journals (of which reviews, editorials), 108 peer-reviewed articles in books, 11 International Patents.

 Full paper list is available at www.peptlab.eu

Communication of the scientific activity

2000-2020: invited to present 127 lectures: 100 lectures in International Symposia (keynotes, invited and plenary), Universities and Research Centres (EU, USA, Canada, Australia, Israel, Japan, China) and 27 lectures aimed to technology transfer in the global space of R&D. 1997-2020: 59 oral & 251 poster communications were selected in international symposia and presented by her students or co-workers or personally.

Prof. Anna Maria Papini, PhD ORCID: 0000-0002-2947-7107

PUBLICATIONS IN JOURNALS

1983-2020 

1983-1990

[1] M. Taddei, A.M. Papini, M. Fiorenza, A. Ricci, G. Seconi. Ring opening reactions of thiiranes with group IVB organometallics: a new regioselective route to b-amino and b-cyanide thiols. Tetrahedron Lett 1983; 24(22), 2311-2314. DOI: 10.1016/S0040-4039(00)81911-5

Published by ELSEVIER SCIENCE INC, STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA, MAY 1983.

IF: 2,125 - Citations: 14 (Scopus).

[2] A.M. Papini, A. Ricci, M. Taddei, G. Seconi and P. Dembech. Regiospecific Conversion of Oxiranes, Oxetanes, and Lactones into Difunctional Nitrogen Compounds via Aminosilanes and Aminostannanes. J Chem Soc Perkin Trans I 1984; 2261-2265. ISSN: 14727781

Published by ROYAL SOCIETY OF CHEMISTRY, CAMBRIDGE, ENGLAND, OCTOBER 1984.

IF: 2,42 - Citations: 51 (Scopus).

[3] S. Francalanci, S. Giorgini, M. Gola, M. Ginanneschi, A.M. Papini and A. Sertoli. Eczema da contatto da antifungino topico. Boll. Dermatol. Allergol. e professionale (1986) 1, 9-13.

[4] M. Ginanneschi, A. Sertoli, A.M. Papini, G. Rapi. Chemical aspects of hapten-carrier interaction in contact allergy. Giorn It Derm Vener 1987; 122(7-8), 389-395. PubMed ID 3666799. ISSN: 00264741

Published by EDIZIONI MINERVA MEDICA, TORINO, ITALY, JULY-AUGUST 1987

IF: 1,327 - Citations: 0 (Scopus).

[5] S. Giuliani, R. Amann, A.M. Papini, C.A. Maggi, A. Meli. Modulatory action of galanin on responses due to antidromic activation of peripheral terminals of capsaicin-sensitive sensory nerves. Eur J Pharmacol 1989; 163(1), 91-96. DOI: 101016/0014-2999(89)90399-3

Published by ELSEVIER, Amsterdam, THE NETHERLANDS, APRIL 1989.

IF: 3,04 - Citations: 50 (Scopus); 55 (WoS).

[6] M. Ginanneschi, M. Chelli, A.M. Papini, G. Rapi. Highly efficient synthesis of steroid-17-spiro-5’-oxazolidine-2’,4’-diones from 17-keto steroids. Steroids 1990; 55(11), 501-506. DOI:10.1016/0039-128X(90)90088-S

Published by ELSEVIER, STONEHAM, MA, USA, NOVEMBER 1990.

IF: 2,523 - Citations: 7 (Scopus).

[7] M. Chelli, G. Dupuis, S. Evangelista, M. Ginanneschi, A. Meli, A.M. Papini, G. Rapi. Suppression of the skin response to alantolactone in alantolactone-sensitized guinea pigs treated with N-acetyl-l-cysteinyl-l-alanine methyl ester. Eur J Med Chem 1990; 25(2), 107-115. DOI: 10.1016/0223-5234(90)90017-W

Published by ELSEVIER, PARIS, FRANCE, MARCH 1990.

IF: 4,816 - Citations: 3 (Scopus); 3 (WoS).

1991-1998

[8] R. von Grünigen, G. Siglmüller, A.M. Papini, K. Köcher, B. Traving, W. Göhring, L. Moroder. Enzyme Immunoassay with Captured Hapten. A sensitive Gastrin Assay with Biotinyl-Gastrin Derivatives. Biol Chem Hoppe-Seyler 1991; 372(3), 163-172. DOI: 10.1515/bchm3.1991.372.1.163

Published by DE GRUYTER, BERLIN, GERMANY, MARCH 1991.

IF: 3,022 - Citations: 11 (Scopus); 11 (WoS).

[9] A.M. Papini, S. Rudolph, G. Siglmüller, H.-J. Musiol, W. Göhring, L. Moroder. Alkylation of histidine with maleimido-compounds. Int J Pept Prot Res 1992; 39(4), 348-355. DOI: 10.1111/j.1399-3011.1992.tb01594.x

Published by WILEY, COPENHAGEN, DENMARK, APRIL 1992.

IF: 1,432 - Citations: 18 (Scopus); 20 (WoS).

[10] D. Donati, M. Ginanneschi, M. Chelli, G. Rapi, A.M. Papini. X-ray structure analysis of 3,11,17-trioxoandrostane-5a-carbonitrile and of 17a-ethoxycarbonyloxy-3-oxoandrost-4-ene-17-carbonitrile. Steroids 1992; 57(10), 502-506. DOI: 10.1016/0039-128X(92)90045-B

Published by ELSEVIER, STONEHAM, MA, USA, OCTOBER 1992.

IF: 2,523 - Citations: 0 (Scopus); 0 (WoS).

[11] L. Moroder, A.M. Papini, G. Siglmüller, K. Köcher, E. Dörrer, C.H. Schneider. Induction and Detection of anti-peptide antibody specificity is critically affected by the mode of hapten presentation. Biol Chem Hoppe-Seyler 1992; 373(6), 315-321. DOI: 10.1515/bchm3.1992.373.315

Published by DE GRUYTER, BERLIN, GERMANY, JUNE 1992.

IF: 3,022 - Citations: 3 (Scopus); 3 (WoS).

[12] M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani, G. Rapi. Cyclization of C-Terminal Histidine Peptides to 7-Amino-dihydroimidazo[1,5-c]pyrimidin-5-one Derivatives. J Chem Research - S 1993; 3:118-119.

Pubblicato Published by ROYAL SOCIETY OF CHEMISTRY, CAMBRIDGE, ENGLAND, MARCH 1993.

IF: 0,61 - Citations: 2 (WoS).

[13] M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani, G. Rapi, E. Borghi, F. Laschi, M. Occhiuzzi. Complexation properties of Histidyl-Glycyl-containing peptides. Part 1. Synthesis of cyclo(L-His-Gly)4^. J Chem Research - S 1993; 11:437-437 and J Chem Res - M 1993; 11:2929-2938.

Published by ROYAL SOCIETY OF CHEMISTRY, CAMBRIDGE, ENGLAND, NOVEMBER 1993.

IF: 0,61 - Citations: 2 (WoS).

[14] E. Borghi, F. Laschi, M. Occhiuzzi, M. Chelli, M. Ginanneschi, A.M. Papini; G. Rapi. Complexation properties of Histidyl-Glycyl containing peptides. Part 2. An X-band EPR study of divalent paramagnetic metal ions interacting in solution with H-(L-His-Gly)2-OMe. J Chem Research - S 1994; 1:48-49.

Published by ROYAL SOCIETY OF CHEMISTRY, CAMBRIDGE, ENGLAND, JANUARY 1994.

IF: 0,61 - Citations: 4 (WoS).

[15] D. Pinzani, A.M. Papini, M. Chelli, M. Ginanneschi, C.A. Maggi, R. Patacchini, L. Quartara; G. Rapi. Synthesis and biological activity of tachykinin analogs containing the adamantane moiety. Lett Pept Sci 1996; 2(5), 307-313. DOI: 10.1007/BF00142244

Published by SPRINGER VERLAG, LEIDEN, THE NETHERLAND, FEBRUARY 1996

IF: 0,406 - Citations: 0 (Scopus).

[16] M. Ginanneschi, M. Chelli, A.M. Papini, D. Pinzani; G. Rapi. Structure of the adduct of Alantolactone with Z-l-Cys-l-Ala-OMe and 1H and 13C assignment of the Alantolactone moiety by 14 Tesla NMR. Magn Reson Chem 1996; 34(2), 95-99. DOI: 10.1002/(SICI)1097-458X(199602)34

Published by WILEY, CHICHESTER, W. SUSSEX, ENGLAND, FEBRUARY 1996.

IF: 1,776 - Citations: 7 (Scopus); 8 (WoS).

[17] D. Pinzani, A.M. Papini, M.E. Vallecchi, M. Chelli, M. Ginanneschi, G. Rapi, L. Quartara, R. Patacchini, C.A. Maggi, F.M. Arcamone. Glycosyl derivatives of NK2 tachykinin receptor antagonists. Bioorg Med Chem Lett1996; 6(4), 367-372. DOI: 10.1016/0960-894X(96)00039-X

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, FEBRUARY 1996

IF: 2,442 - Citations: 7 (Scopus); 6 (WoS).

[18] G. Giorgi, M. Ginanneschi, M. Chelli, A.M. Papini, F. Laschi, E. Borghi. Histidyl-Glycyl containing peptides. Characterization and complexation properties of H(L-His-Gly)₂-R with hydrogen and alkali metal ions in the gas-phase. Rapid Commun Mass Spectrom 1996; 10(10), 1266-1272. DOI: 10.1002/(SICI)1097-0231(19960731)10

Published by WILEY, CHICHESTER, W. SUSSEX, ENGLAND, OCTOBER 1996.

IF: 1,97 - Citations: 9 (Scopus); 9 (WoS);  (Google Scholar)

[19] G. Caminati, A.M. Papini, S. Mazzucco, G. Gabrielli. Lipopeptides of myelin basic protein in mono- and multilayers. Thin Solid Films 1998; 327:37-41. DOI: 10.1016/S0040-6090(98)00583-5

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 31 AUGUST 1998.

IF: 1,939 - Citations: 0 (Scopus); 0 (WoS).

[20] M. Ciuffi, C. Cellai, S. Franchi-Micheli, P. Failli, L. Zilletti, M. Ginanneschi, M. Chelli, A.M. Papini; F. Paoletti. An in vivo, ex vivo and in vitro comparative study of activity of copper oligopeptide complexes vs Cu(II) ions. Pharmacol Res 1998; 38(4), 279-287. DOI: 10.1006/phrs.1998.0369

Published byPERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, FEBRUARY 1998.

IF: 4,897 - Citations: 14 (Scopus); 11 (WoS).

1999

[21] S. Mazzucco, E. Nardi, M. Chelli, M. Ginanneschi, G. Rapi, A.M. Papini, M. Vergelli, B. Mazzanti, L. Massacesi, L. Amaducci. Synthesis of lipopeptides of the immunodominant epitope hMBP(83-99) containing amide or C-C bond linked hydrophobic chains for the study of T cell response. Lett Pept Sci 1999; 6(1), 51-59. DOI: 10.1007/BF02443618

Published by SPRINGER VERLAG, DORDRECH, THE NETHERLAND, JANUARY 1999.

IF: 0,406 - Citations: 3 (Scopus); 5 (WoS).

[22] G. Sabatino, M. Chelli, S. Mazzucco, M. Ginanneschi, A.M. Papini. Cyclisation of Histidine Containing Peptides in the Solid-Phase by Anchoring the Imidazole Ring to Trityl Resins. Tetrahedron Lett 1999; 40(4), 809-812. DOI: 10.1016/S0040-4039(98)02459-9

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, JANUARY 1999.

IF: 2,125 - Citations: 38 (Scopus); 37 (WoS).

[23] S. Mazzucco, S. Matà, M. Vergelli, R. Fioresi, E. Nardi, B. Mazzanti, M. Chelli, F. Lolli, M. Ginanneschi, F. Pinto, L. Massacesi, A.M. Papini. A synthetic glycopeptide of human Myelin Oligodendrocyte Glycoprotein to detect antibody responses in Multiple Sclerosis and other neurological diseases. Bioorg Med Chem Lett 1999; 9(2), 167-172. DOI: 10.1016/S0960-894X(98)00698-2

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, JANUARY 1999.

IF: 2,442 - Citations: 28 (Scopus); 35 (WoS).

[24] M. Casolaro, M. Chelli, M. Ginanneschi, F. Laschi, M. Muniz-Miranda, A.M. Papini, G. Sbrana. Spectroscopic and potentiometric study of copper(ii) complexes with l-histidyl-glycyl-l-histidyl-glycine in aqueous solution. Spectrochimica Acta Part A, Mol & Biomol Spectroscopy 1999; 55(7-8), 1675-1689. DOI: 10.1016/S1386-1425(98)00328-X

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, JULY-AUGUST 1999.

IF: 2,88 - Citations: 26 (Scopus); 27 (WoS).

[25] C. Galoppini, S. Meini, M. Tancredi, A. Di Fenza, A. Triolo, L. Quartara, C.A. Maggi, F. Formaggio, C. Toniolo, S. Mazzucco, A.M. Papini, P. Rovero. A new class of pseudopeptide antagonists of the kinin B1 receptor containing alkyl spacers. J Med Chem 1999; 42(3), 409-414. DOI: 10.1021/jm980495r

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, 11 FEBRUARY 1999.

IF: 6,253 - Citations: 26 (Scopus); 21 (WoS).

2001

[26] C. Giragossian, E. Nardi, C. Savery, M. Pellegrini, S. Meini, C.A. Maggi, A.M. Papini,D. Mierke. Structural characterization of lipopeptide agonists for the Bradykinin B2 receptor. Biopolymers 2001; 58(5), 511-520. DOI: 10.1002/1097-0282(20010415)58

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 20 FEBRUARY 2001

IF: 1,99 - Citations: 3 (Scopus); 3 (WoS).

[27] A.M. Papini, B. Mazzanti, E. Nardi, E. Traggiai, C. Ballerini, T. Biagioli, H. Kalbacher, H. Beck, M. Deeg, M. Chelli, M. Ginanneschi, L. Massacesi, M. Vergelli. Palmitoyl Derivatives of GpMBP Epitopes: T-Cell Response and Peptidases Susceptibility. J Med Chem 2001; 44(21), 3504-3510. DOI: 10.1021/jm010913j

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, SEPTEMBER 13, 2001

IF: 6,253 - Citations: 7 (Scopus); 7 (WoS).

[28] F. Meyer, J. Uziel, A.M. Papini, S. Jugé. Triphenylphosphonium salts bearing an l-alanyl substituents: short synthesis and enantiomeric analysis by NMR. Tetrahedron Lett 2001; 42(24), 3981-3984. DOI: 10.1016/S0040-4039(01)00650-5

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 11 JUNE 2001

IF: 2,125 - Citations: 11 (Scopus); 11 (WoS).

[29] A. Carotenuto, A.M. D’Ursi, E. Nardi, A.M. Papini, P. Rovero. Conformational analysis of a glycosylated Human Oligodendrocyte Glycoprotein peptide epitope able to detect antibody response in Multiple Sclerosis. J Med Chem 2001; 44(14), 2378-2381. DOI: 10.1021/jm010811t

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, JUNE 7, 2001

IF: 6,253 - Citations: 32 (Scopus); 33 (WoS).

2002

[30] E. Peroni, G. Caminati, P. Baglioni, F. Nuti, M. Chelli,A.M. Papini. A New lipophilic fluorescent probe for interaction studies of bioactive lipopeptides with membrane models. Bioorg Med Chem Lett2002; 12(13), 1731-1734. DOI: 10.1016/S0960-894X(02)00253-6

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 8 JULY 2002

IF: 2,442 - Citations: 15 (Scopus); 15 (WoS).

[31] M. Casolaro, M. Chelli, M. Ginanneschi, F. Laschi, L. Messori, M. Muniz-Miranda, A.M. Papini, T. Kowalik-Jankowska, H. Kozlowski. Spectroscopic and potentiometric study of the SOD mimic system Copper/Acetyl-L-histidyl-glycyl-L-histidyl-glycine. J Inorganic Biochem 2002; 89(3-4), 181-190. DOI: 10.1016/S0162-0134(02)00365-3

Published by ELSEVIER SCIENCE INC, STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA, 1 APRIL 2002

IF: 3,063 - Citations: 49 (Scopus); 52 (WoS).

[32] A.M. Papini,E. Nardi, F. Nuti, J. Uziel, M. Ginanneschi, M. Chelli, A. Brandi. Diastereoselective alkylation of Schiff bases for the synthesis of lipidic unnatural Fmoc-protected a-amino acids. Eur J Org Chem2002; 16, 2736-2741. DOI: 10.1002/1099-0690(200208)2002:16<2736

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, 19 JULY 2002

IF: 2,882 - Citations: 13 (Scopus); 10 (WoS).

[33] C. Giragossian, S. Stone, A.M. Papini, L. Moroder, D.F. Mierke. Conformational and molecular modeling studies of sulfated cholecystokinin-15. Biochem Biophys Res Commun 2002; 293(3), 1053-1059. DOI: 10.1016/S0006-291X(02)00334-0

Published by ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA, 1 MAY 2002

IF: 2,559 - Citations: 9 (Scopus); 9 (WoS).

[34] G. Sabatino, B. Mulinacci, M.C. Alcaro, M. Chelli, P. Rovero, A.M. Papini. Assessment of new 6Cl-HOBt based coupling reagents for peptide synthesis. Part 1: Coupling efficiency study. Lett Pept Sci 2002; 9(2-3), 119-123. DOI: 10.1007/BF02576873

Published by SPRINGER, VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS, MARCH 2002

IF: 0,406 - Citations: 47 (Scopus); 47 (WoS).

2003

[35] G. Sabatino, M. Chinol, G. Paganelli, S. Papi, M. Chelli, G. Leone, A.M. Papini, A. De Luca, M. Ginanneschi. ANew Biotin Derivative-DOTA Conjugate as a candidate for pre-targeted diagnosis and therapy of tumors. J Med Chem2003; 46(14):3170-3173. DOI: 10.1021/jm030789z

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, JUNE 5, 2003

IF: 6,253 - Citations: 41 (Scopus); 39 (WoS).

[36] M.C. Alcaro, M. Orfei, M. Chelli, M. Ginanneschi, A.M. Papini. Solid-phase approach to the synthesis of cyclen derivatives from cyclotetrapeptides. Tetrahedron Letters 2003; 44(28):5217-5219. DOI: 10.1016/S0040-4039(03)01213-9

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 7 JULY 2003

IF: 2,125 - Citations: 10 (Scopus); 10 (WoS).

[37] F. Meyer, A. Laaziri,A.M. Papini, J. Uziel, S. Jugé. Efficient synthesis of b-halogeno protected L-alanines and their b-phosphonium derivatives. Tetrahedron Asymmetry 2003; 14(15):2229-2238. DOI: 10.1016/S0957-4166(03)00484-1

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 1 AUGUST 2003

IF: 2,126 - Citations: 14 (Scopus); 16 (WoS).

[38] M.C. Alcaro, E. Peroni, P. Rovero, A.M. Papini. Synthetic peptides in the diagnosis of HIV infection. REVIEW. Current Protein and Peptide Science 2003; 4(4):285-290. DOI: 10.2174/1389203033487117

Published byBENTHAM SCIENCE PUBL LTD, EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES, in 2003

IF: 2,696 - Citations: 26 (Scopus); 22 (WoS).

[39] F. Lolli, B. Mazzanti, P. Rovero, A.M. Papini. Synthetic peptides in the diagnosis of neurological diseases. REVIEW. Current Protein and Peptide Science2003; 4(4):277-284. DOI: 10.2174/1389203033487162

Published by BENTHAM SCIENCE PUBL LTD, EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES, in 2003

IF: 2,696 - Citations: 3 (Scopus); 1 (WoS).

2004

[40] M.C. Alcaro, G. Sabatino, J. Uziel, M. Chelli, M. Ginanneschi, P. Rovero, A.M. Papini.On-resin head-to-tail cyclization of cyclotetrapeptides: optimization of crucial parameters. J Pept Sci 2004; 10(4), 218-228. DOI: 10.1002/psc.512.

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 10 NOVEMBER 2003

IF: 1,969 - Citations: 45 (Scopus); 47 (WoS).

[41] F. Meyer, A. Laaziri,A.M. Papini, J. Uziel, S. Jugé. A novel phosphorus-carbon bond formation by ring opening with diethyl phosphite of oxazolines derived from serine. Tedrahedron 2004; 60(16), 3593-3597. DOI: 10.1016/j.tet.2004.03.001

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 12 APRIL 2004

IF: 2,377 - Citations: 19 (Scopus); 20 (WoS).

[42] F. Machetti, F.M. Cordero, F. De Sarlo, A.M. Papini, M.C. Alcaro, A. Brandi. Synthesis of free and N^a-Fmoc/N^a-Boc protected (2S, 4S)- and (2S, 4R)-4-aminopipecolic acids. Eur J Org Chem 2004; 13, 2928-2935. DOI: 10.1002/ejoc.200400045

Published by WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, 15 JUNE 2004

IF: 2,882 - Citations: 16 (Scopus); 16 (WoS).

[43] A. Innocenti, A. Casini, M.C. Alcaro, A.M. Papini, A. Scozzafava,C.T. Supuran. Carbonic anhydrase inhibitors: The first on-resin screening of a 4-sulfamoylphenylthioureas library. J Med Chem 2004; 47(21), 5224-5229. DOI: 10.1021/jm049692i.

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, AUGUST 25, 2004

IF: 6,253 - Citations: 44 (Scopus); 43 (WoS).

[44] G. Caminati, E. Peroni, A.M. Papini, P. Baglioni. Photophysical investigation of lipopeptides of myelin basic protein in phospholipid vesicles. Progress in Colloid & Polymer Science 2004; 126, 163-168. DOI: 10.1007/b93987

Published by SPRINGER-VERLAG BERLIN, HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY, OCTOBER 2004

IF: n.a. - Citations: 1 (Scopus).

[45] G. Sabatino, M. Chelli, A. Brandi, A.M. Papini.Analytical methods for solid phase peptide synthesis. Current Organic Chemistry 2004; 8(4), 291-301. DOI: 10.2174/1385272043485954

Published by BENTHAM SCIENCE PUBL LTD, EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES, in 2004

IF: 2,193 - Citations: 5 (Scopus); 4 (WoS).

2005

[46] A. Carotenuto, D. D’Addona, E. Rivalta, M. Chelli, A.M. Papini, P. Rovero, M. Ginanneschi. Synthesis of a dicarba-analogue of octreotide keeping the type II’ b-turn of the pharmacophore in water solution. Lett Org Chem 2005; 2(3), 274-279. DOI: 10.2174/1570178053765276

Published by BENTHAM SCIENCE PUBL LTD, EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES, in 2005

IF: 0,539 - Citations: 13 (Scopus); 16 (WoS).

[47] J. Matsoukas, V. Apostolopoulos, H. Kalbacher, A.M. Papini, T. Tselios, K. Chatzantoni, T. Biagioli, F. Lolli, S. Deraos, P. Papathanassopoulos, A. Troganis, E. Mantzourani, T. Mavromoustakos, A. Mouzaki. Design and synthesis of a novel potent myelin basic protein epitope 87-99 cyclic analogue: enhanced stability and biological properties of mimics render them a potentially new class of immunomodulators. J Med Chem 2005; 48(5), 1470-1480. DOI: 10.1021/jm040849g

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, FEBRUARY 15, 2005

IF: 6,253 - Citations: 54 (Scopus); 56 (WoS).

[48] F. Nuti, S. Hildenbrand, M. Chelli, R. Wodarzb, A.M. Papini.Synthesis of DEHP metabolites as biomarkers for GC-MS evaluation of phthalates as endocrine disrupters. Bioorg Med Chem 2005; 13(10), 3461-3465. DOI: 10.1016/j.bmc.2005.03.005

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 1 MAY 2005

IF: 2,881 - Citations: 16 (Scopus); 15 (WoS).

[49] A.M. Papini. Simple test for Multiple Sclerosis. Nature Medicine2005; 11(1), 13. DOI: 10.1038/nm0105-13

Published by NATURE PUBLISHING GROUP, 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA, 1 JANUARY 2005

IF: 32,621 - Citations: 11 (Scopus); 35 (WoS).

[50] Lolli F, Mulinacci B, Carotenuto A, Bonetti B, Sabatino G, Mazzanti B, D'Ursi AM, Novellino E, Pazzagli M, Lovato L, Alcaro MC, Peroni E, Pozo-Carrero MC, Nuti F, Battistini L, Borsellino G, Chelli M, Rovero P, Papini AM. An N-glucosylated peptide detecting disease-specific autoantibodies, biomarkers of multiple sclerosis. Proc Natl Acad Sci USA 2005; 102(29):10273-10278. DOI: 10.1073/pnas.0503178102

Published by NATL ACAD SCIENCES, 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA, 19 JULY, 2005

IF: 9,504 - Citations: 86 (Scopus); 134 (WoS).

[51] F. Lolli, B. Mazzanti, M. Pazzagli, E. Peroni, M.C. Alcaro, R. Lanzillo, V. Brescia Morra, L. Santoro, C. Gasperini, S. Galgani, M.M. D’ Elios, V. Zipoli, S. Sotgiu, M. Pugliatti, P. Rovero, M. Chelli, A.M. Papini.The glycopeptide CSF114(Glc) detects serum antibodies in Multiple Sclerosis. J Neuroimmunol 2005; 167(1-2), 131-137. DOI: 10.1016/j.jneuroim.2005.05.016

Published by ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, OCTOBER 2005

IF: 2,655 - Citations: 44 (Scopus); 75 (WoS).

[52] S. Giannecchini, M.C. Alcaro, P. Isola, O. Sichi, M. Pistello, A.M. Papini, P. Rovero, M. Bendinelli. Feline immunodeficiency virus plasma load reduction by a retroinverso octapeptide reproducing the Trp-rich motif of the transmembrane glycoprotein. Antiviral Therapy 2005; 10(5), 671-680.

Published by INT MEDICAL PRESS LTD, 2-4 IDOL LANE, LONDON EC3R 5DD, ENGLAND, 1 JANUARY 2005

IF: 2,146 - Citations: 14 (Scopus); 12 (WoS).

[53] F. Lolli, P. Rovero, M. Chelli, A.M. Papini.Antibodies against glycosylated native MOG are elevated in patients with Multiple Sclerosis. Neurology 2005 65(5), 781-782.

LIPPINCOTT WILLIAMS & WILKINS, TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA, SEPTEMBER 13, 2005

IF: 8,055 - Citations: 3 (Scopus); 4 (WoS).

[54] Kamiński ZJ, Kolesińska B, Kolesińska J, Sabatino G, Chelli M, Rovero P, Błaszczyk M, Główka ML, Papini AM. N-triazinylammonium tetrafluoroborates. A new generation of efficient coupling reagents useful for peptide synthesis. J Am Chem Soc 2005; 127(48):16912-16920. DOI: 10.1021/ja054260y

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, NOVEMBER 10, 2005

IF: 14,357 - Citations: 112 (Scopus); 116 (WoS).

2006

[55] F. Minutolo, S. Bertini, L. Betti, R. Danesi, G. Gervasi, G. Giannaccini, A. Martinelli, A.M. Papini, E. Peroni, G. Placanica, S. Rapposelli, T. Tuccinardi, M. Macchia. Synthesis of stable snalogues of geranylgeranyl Diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition. CHEMMEDCHEM 2006; 1(2), 218-224.  DOI: 10.1002/cmdc.200500010

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, FEBRUARY 2006

IF: 3,009 - Citations: 7 (Scopus); 7 (WoS).

[56] A.M. D’Ursi, S. Giannecchini, C. Esposito, M.C. Alcaro, O. Sichi, M.R. Armenante, A. Carotenuto, A.M. Papini, M. Bendinelli, P. Rovero. Development of antiviral fusion inhibitors: short modified peptides derived from the transmembrane glycoprotein of feline immunodeficiency virus. CHEMBIOCHEM 2006; 7(5), 774-779. DOI: 10.1002/cbic.200500390

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, MAY 2006

IF: 2,774 - Citations: 16 (Scopus); 17 (WoS).

[57] Alcaro MC, Vinci V, D'Ursi AM, Scrima M, Chelli M, Giuliani S, Meini S, Di Giacomo M, Colombo L, Papini AM. Bradykinin antagonists modified with dipeptide mimetic beta-turn inducers. Bioorg Med Chem Lett 2006; 16(9):2387-2390. DOI: 10.1016/j.bmcl.2006.01.125

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 28 FEBRUARY 2006

IF: 2,442 - Citations: 6 (Scopus); 6 (WoS).

[58] M.C. Alcaro, A.M. Papini. Contribution of peptides to Multiple Sclerosis research. Biopolymers 2006; 84(4), 349-367. DOI: 10.1002/bip.20498

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2006

IF: 1,99 - Citations: 9 (Scopus); 7 (WoS).

[59] V.V. Volkov, F. Nuti, Y. Takaoka, R. Chelli, A.M. Papini, R. Righini. Hydration and hydrogen bonding of carbonyls in dimyristoyl-phospahtidylcholine bilayer. J Am Chem Soc2006; 128(29), 9466-9471. DOI: 10.1021/ja0614621

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, JULY 26, 2006

IF: 14,357 - Citations: 24 (Scopus); 24 (WoS).

[60] A. Carotenuto, A.M. D’Ursi, B. Mulinacci, I. Paolini, F. Lolli, A.M. Papini, E. Novellino, P. Rovero. Conformation-activity relationship of designed glycopeptides as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis. J Med Chem 2006; 49(17), 5072-5079. DOI: 10.1021/jm060117j

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, AUGUST 24, 2006

IF: 6,253 - Citations: 25 (Scopus); 38 (WoS).

[61] F. Lolli, P. Rovero, M. Chelli, A.M. Papini. Toward biomarkers in multiple sclerosis: new advances. Expert Review Neurotherapeutics 2006; 6(5), 781-794. DOI: 10.1586/14737175.6.5.781

Published by TAYLOR & FRANCIS LTD, 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND, MAY 2006

IF: 3,696 - Citations: 5 (Scopus); 7 (WoS).

2007

[62] Rizzolo F, Sabatino G, Chelli M, Rovero P, Papini AM. A convenient microwave-enhanced solid-phase synthesis of difficult peptide sequences: case study of Gramicidin A and CSF114(Glc). Int J Pept Res Ther 2007; 13(1-2), 203-208. DOI:10.1007/s10989-006-9066-8

Published by SPRINGER, 233 SPRING STREET, NEW YORK, NY 10013 USA, JUNE 2007

IF: 1,132 - Citations: 55 (Scopus); 51 (WoS).

[63] K. Jastrząbek, B. Kolesińska, G. Sabatino, F. Rizzolo, A.M. Papini, Z.J. Kamiński. Benzyloxy derivatives of triazine-based coupling reagents designed for an efficient solid phase peptide synthesis on polystyrene resin. Int J Pept Res Ther 2007; 13(1-2), 229-236. DOI: 10.1007/s10989-006-9071-y

Published by SPRINGER, 233 SPRING STREET, NEW YORK, NY 10013 USA, JUNE 2007

IF: 1,132 - Citations: 12 (Scopus); 12 (WoS).

[64] B. Kolesińska, J. Frączyk, G. Sabatino, A.M. Papini, Z.J. Kamiński. Sulfonates of N-triazinylammonium salts as highly efficient, inexpensive and environmentally friendly coupling reagents for peptide synthesis. Chimica oggi-Chemistry Today 2007; 25(1), 10-13.

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, in 2007

IF: 0,396 - Citations: 11 (Scopus); 12 (WoS).

[65] I. Paolini, F. Nuti, M.C. Pozo-Carrero, F. Barbetti, B. Kolesinska, Z.J. Kaminski, M. Chelli, A.M. Papini. A convenient microwave-assisted synthesis of N-glycosyl amino acids. Tetrahedron Letters 2007; 48(16), 2901-2904. DOI: 10.1016/j.tetlett.2007.02.087

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 16 APRIL 2007 (online 22 FEBRUARY 2007)

IF: 2,125 - Citations: 31 (Scopus); 10 (WoS).

[66] F. Nuti, I. Paolini, F. Cardona, M. Chelli, F. Lolli, A. Brandi, A. Goti, P. Rovero, A.M. Papini. Fmoc-protected iminosugar modified asparagine derivatives as building blocks for glycomimetics-containing peptides. Bioorg Med Chem 2007; 15(12), 3965-3973.

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 15 JUNE 2007

IF: 2,881 - Citations: 12 (Scopus); 12 (WoS).

[67] M.C. Alcaro, F. Lolli, P. Migliorini, M. Chelli, P. Rovero, A.M. Papini. Peptides as autoimmune diseases antigenic probes: a peptide-based reverse approach to detect biomarkers of autoimmune diseases. Chimica oggi-Chemistry Today 2007; 25(3S), 14-16.

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, in 2007

IF: 0,396 - Citations: 13 (Scopus); 24 (WoS).

[68] V.V. Volkov, R. Chelli, W. Zhuang, F. Nuti, Y. Takaoka, A.M. Papini, S. Mukamel, R. Righini. Electrostatic interactions in phospholipid membranes revealed by coherent two-dimensional infrared spectroscopy. Proc Natl Acad. Sci, USA 2007; 104(39):15323-15327. DOI:  10.1073/pnas.0706426104

Published by NATL ACAD SCIENCES, 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA, SEPTEMBER 25, 2007

IF: 9,504 - Citations: 23 (Scopus); 23 (WoS).

2008

[69] D'Addona D, Carotenuto A, Novellino E, Piccand V, Reubi JC, Di Cianni A, Gori F, Papini AM, Ginanneschi M. Novel sst5-selective somatostatin dicarba-analogues: synthesis and conformation-affinity relationships. J Med Chem 2008; 51(3):512-520. DOI: 10.1021/jm070886i

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, FEBRUARY 14, 2008

IF: 6,253 - Citations: 39 (Scopus); 37 (WoS).

[70] F. Real Fernández, A. Chamois-Colson, J. Bayardon, F. Nuti, E. Peroni, R. Meunier-Prest, F. Lolli, M. Chelli, C. Darcel, S. Jugè, A.M. Papini. Ferrocenyl Glycopeptides as Electrochemical Probes to Detect Autoantibodies in Multiple Sclerosis Patients’ Sera. Biopolymers2008; 90(4):488-495. DOI: 10.1002/bip.20955

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, in 2008

IF: 1,99 - Citations: 24 (Scopus); 16 (WoS).

[71] Cantel S, Isaad Ale C, Scrima M, Levy JJ, DiMarchi RD, Rovero P, Halperin JA, D'Ursi AM, Papini AM, Chorev M. Synthesis and conformational analysis of a cyclic peptide obtained via i to i+4 intramolecular side-chain to side-chain azide-alkyne 1,3-dipolar cycloaddition. J Org Chem 2008; 73(15), 5663-5674. DOI: 10.1021/jo800142s. FEATURED ARTICLE AND COVER.

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, AUGUST 1, 2008

IF: 4,805 - Citations: 126 (Scopus); 127 (WoS).

[72] I. Paolini, F. Rizzolo, A.M. Papini. Optimized strategies for the synthesis of biomolecules by the microwave approach. Chimica Oggi-Chemistry Today 2008;26(4S), 35-38.

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, JULY 2008

IF: 0,396 - Citations: 0 (Scopus); 0 (WoS).

[73] A. Carotenuto, M.C. Alcaro, M.R. Saviello, E. Peroni, F. Nuti, A.M. Papini, E. Novellino, P. Rovero. Designed glycopeptides with different b-turn types as synthetic probes for the detection of autoantibodies, biomarkers of Multiple Sclerosis. J Med Chem 2008; 51(17), 5304-5309. DOI: 10.1021/jm800391y

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, AUGUST 20, 2008

IF: 6,253 - Citations: 23 (Scopus); 26 (WoS).

[74] Le Chevalier Isaad A, Barbetti F, Rovero P, D’Ursi AM, Chelli M, Chorev M, Papini AM. N(alpha)-Fmoc-Protected omega-Azido and omega-Ynoic-alpha-Amino Acids as Building Blocks for the Synthesis of "Clickable" Peptides. Eur J Org Chem 2008; 31:5308-5314. DOI: 10.1002/ejoc.200800717

Published by WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, NOVEMBER 2008

IF: 2,882 - Citations: 26 (Scopus); 26 (WoS).

[75] G. Sabatino, A.M. Papini. Advances in automatic, manual and microwave-assisted solid-phase peptide synthesis. REVIEW. Current Opinion in Drug Discovery & Development 2008; 11(6), 762-768.

Published by THOMSON REUTERS (SCIENTIFIC) LTD, 77 HATTON GARDEN, LONDON, EC1N 8JS, ENGLAND, 01 NOVEMBER 2008

IF: 5,121 - Citations: 53 (Scopus); 52 (WoS).

2009

[76] S. Carganico, P. Rovero, J. A. Halperin, A.M. Papini, M. Chorev Building Blocks for the Synthesis of Post-Translationally Modified Glycated Peptides and Proteins. J Pept Sci 2009; 15(2), 67-71. DOI: 10.1002/psc.1105

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, FEBRUARY 2009

IF: 1,969 - Citations: 10 (Scopus); 10 (WoS).

[77] M.C. Alcaro, I. Paolini, F. Lolli, P. Migliorini, P. Rovero, A.M. Papini. Peptide contribution to the diagnosis of autoimmune diseases. Chimica Oggi-Chemistry Today 2009; 27(2), 11-14.

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, MARCH-APRIL 2009

IF: 0,396 - Citations: 3 (WoS).

[78] M. Angeles Bonache, F. Nuti, A. Le Chevalier Isaad, F. Real-Fernandez, M. Chelli, P. Rovero, A.M. Papini. Synthesis of new ribosylated Asn building blocks as useful tools for glycopeptide and glycoprotein synthesis. Tetrahedron Lett 2009; 50(28), 4151-4153. DOI: 10.1016/j.tetlet.2009.04.124

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 15 JULY 2009

IF: 2,125 - Citations: 8 (Scopus); 8 (WoS).

[79] A. Le Chevalier-Isaad, A.M. Papini, M. Chorev, P. Rovero. Side chain-to-side chain cyclization by click reaction. J Pept Sci 2009; 15(7), 451-454. DOI: 10.1002/psc.1141

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, JULY 2009

IF: 1,969 - Citations: 27 (Scopus); 26 (WoS).

[80] A.M. Papini. The use of post-translationally modified peptides for detection of biomarkers of immune-mediated diseases. REVIEW ZERVAS AWARD LECTURE. J Pept Sci 2009, 15(10), 621-628. DOI: 10.1002/psc.1166

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, OCTOBER 2009

IF: 1,969 - Citations: 28 (Scopus); 36 (WoS).

2010

[81] Scrima M, Le Chevalier-Isaad A, Rovero P, Papini AM, Chorev M, D'Ursi AM. CuI-Catalyzed Azide–Alkyne Intramolecular i-to-(i+4) Side-Chain-to-Side-Chain Cyclization Promotes the Formation of Helix-Like Secondary Structures. Eur J Org Chem 2010; 3:446-457. DOI: 10.1002/ejoc.200901157

Published by WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, JANUARY 2010

IF: 2,882 - Citations: 63 (Scopus); 46 (WoS).

[82] F. Real-Fernández, F. Nuti, M.A. Bonache, M. Boccalini, S. Chimichi, M. Chelli, A.M. Papini. Microwave-assisted reaction of glycosylamine with aspartic acid. Amino Acids 2010; 39(2), 599-604. DOI: 10.1007/s00726-010-0484-8

Published by SPRINGER, 233 SPRING ST, NEW YORK, NY 10013 USA, JULY 2010

IF: 2,906 - Citations: 3 (Scopus); 2 (WoS).

[83] M. Frediani, D. Sémeril, D. Matt, F. Rizzolo, A.M. Papini, P. Frediani, L. Rosi. Ring Opening Polymerization of rac-Lactide using a calix[4]arene-based Titanium (IV) Complex. Published by International Journal of Polymer Science 2010, 490724, 1-6.

HINDAWI PUBLISHING CORPORATION, 410 PARK AVENUE, 15TH FLOOR, #287 PMB, NEW YORK, NY 10022 USA, in 2010

IF: 1,718 - Citations: 6 (Scopus); 9 (WoS).

[84] M. Frediani, D. Sémeril, D. Matt, F. Rizzolo, A.M. Papini, P. Frediani, L. Rosi, M. Santella, G. Giachi. L-Lactide Polymerization by Calix[4]arene-Titanium (IV) Complex Using Conventional Heating and Microwave Irradiation. e-Polymers 2010; 19, 1-8.

Published by EUROPEAN POLYMER FEDERATION, 1, QUAI LEZAY-MARNESIA, F067000 STRASBOURG, FRANCE, FEBRUARY 24, 2010

IF: 1,111 - Citations: 7 (Scopus); 0 (WoS).

[85] F. Nuti, E. Peroni, F. Real-Fernández, M.A. Bonache, A. Le Chevalier-Isaad, M. Chelli, N. Lubin-Germain, J. Uziel, P. Rovero, F. Lolli, A.M. Papini. Post-translationally modified peptides efficiently mimicking neo-antigens: a challenge for theragnostics of autoimmune diseases. Biopolymers 2010; 94(6), 791-799. DOI: 10.1002/bip.21456

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA in 2010

IF: 1,99 - Citations: 11 (Scopus); 12 (WoS).

[86] Di Cianni A, Carotenuto A, Brancaccio D, Novellino E, Reubi JC, Beetschen K, Papini AM, Ginanneschi M. Novel octreotide dicarba-analogues with high affinity and different selectivity for somatostatin receptors. J Med Chem 2010; 53(16):6188-6197. DOI: 10.1021/jm1005868

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, AUGUST 26, 2010

IF: 6,253 - Citations: 27 (Scopus); 26 (WoS).

2011

[87] F. Gori, B. Mulinacci, L. Massai, C. Avolio, M. Caragnano, E. Peroni, S. Lori, M. Chelli, A.M. Papini, P. Rovero, F. Lolli. IgG and IgM antibodies to the refolded MOG(1-125) extracellular domain in humans. J Neuroimmunol 2011; 233(1-2), 216-220. DOI: 10.1016/j.jneuroim.2010.11.011

Published by ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, APRIL 2011

IF: 2,655 - Citations: 7 (Scopus); 8 (WoS).

[88] F. Rizzolo, C. Testa, D. Lambardi, M. Chorev, M. Chelli, P. Rovero, A.M. Papini. Conventional and microwave-assisted SPPS approach: a comparative synthesis of PTHrP(1–34)NH₂. J Pept Sci 2011; 17(10), 708-714. DOI: 10.1002/psc.1395

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, OCTOBER 2011

IF: 1,969 - Citations: 14 (Scopus); 13 (WoS).

[89] C. Selmi, A.M. Papini, P.Pugliese, M.C. Alcaro, M.E. Gershwin. Environmental pathways to autoimmune diseases: the cases of primary biliary cirrhosis and multiple sclerosis, Archives of Medical Science 2011; 7(3), 368-380. DOI: 10.5114/aoms.2011.23398

Published by TERMEDIA PUBLISHING HOUSE LTD, KLEEBERGA ST 2, POZNAN, 61-615, POLAND, JUNE 2011

IF: 2,344 - Citations: 16 (Scopus); 10 (WoS).

2012

[90] C. Testa, F. Nuti, J. Hayek, C. De Felice, M. Chelli, P. Rovero, G. Latini, A.M. Papini. Di(2-ethylhexyl)phthalate and Autism Spectrum Disorders. ASN NEURO (American Society for Neurochemistry) 2012; 4(4), 223-229. DOI:10.1042/AN20120015

Published by PORTLAND PRESS LTD, THIRD FLOOR, EAGLE HOUSE, 16 PROCTER STREET, LONDON WC1V 6 NX, ENGLAND in 2012

IF: 3,617 - Citations: 65 (Scopus); 62 (WoS).

[91] F. Real-Fernández, I. Passalacqua, E. Peroni, M. Chelli, F. Lolli, A.M. Papini, P. Rovero. Glycopeptide-based antibody detection in Multiple Sclerosis by surface plasmon resonance. Sensors2012; 12(5):5596-5607. DOI: 10.3390/s120505596

Published by MDPI AG, POSTFACH, CH-4005 BASEL, SWITZERLAND, MAY 2012

IF: 2,475 - Citations: 19 (Scopus); 18 (WoS).

[92] Scrima M, Grimaldi M, Di Marino S, Testa C, Rovero P, Papini AM, Chorev M, D'Ursi AM. Solvent independent conformational propensities of [1,2,3]triazolyl-bridged parathyroid hormone-related peptide-derived cyclo-nonapeptide analogues. Biopolymers 2012; 98(6):535-545. DOI: 10.1002/bip.22139

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA in 2012

IF: 1,99 - Citations: 1 (Scopus); 2 (WoS).

[93] Guardiani C, Signorini GF, Livi R, Papini AM, Procacci P. Conformational landscape of N-glycosylated peptides detecting autoantibodies in multiple sclerosis, revealed by Hamiltonian replica exchange. J Phys Chem B 2012; 116(18):5458-5467. DOI: 10.1021/jp301442n

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, MAY 10, 2012

IF: 3,146 - Citations: 10 (Scopus); 9 (WoS).

[94] Pandey S, Alcaro MC, Scrima M, Peroni E, Paolini I, Di Marino S, Barbetti F, Carotenuto A, Novellino E, Papini AM, D'Ursi AM, Rovero P. Designed glycopeptides mimetics of myelin protein epitopes as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis. J Med Chem 2012; 55(23):10437-10447. DOI: 10.1021/jm301031r

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, DECEMBER 13, 2012

IF: 6,253 - Citations: 11 (Scopus); 12 (WoS).

2013

[95] Pandey S, Dioni I, Lambardi D, Real-Fernandez F, Peroni E, Pacini G, Lolli F, Seraglia R, Papini AM, Rovero P. Alpha actinin is specifically recognized by multiple sclerosis autoantibodies isolated using an N-glucosylated peptide epitope. Mol Cell Proteomics 2013; 12(2), 277-282. DOI: 10.1074/mcp.M112.017087

Published by AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3996 USA, FEBRUARY 2013

IF: 5,236 - Citations: 8 (Scopus); 10 (WoS).

[96] Potenza M, Sabatino G, Giambi F, Rosi L, Papini AM, Dei L. Analysis of egg-based model wall paintings by use of an innovative combined dot-ELISA and UPLC-based approach. Analytical & Bioanalytical Chemistry 2013; 405(2-3), 691-701. DOI: 10.1007/s00216-012-6049-9

Published by SPRINGER HEIDELBERG, TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY, JANUARY 2013

IF: 3,307 - Citations: 20 (Scopus); 18 (WoS).

[97] Chanson J-B, Paolini I, Collongues N, Alcaro MC, Blanc F., Barbetti F., Fleury M., Peroni E, Rovero P, Rudolf G, Lolli F, Trifilieff E, Papini AM, de Seze J. Evaluation of new immunological targets in neuromyelitis optica. J Pept Sci 2013; 19(1):25-32. DOI: 10.1002/psc.2470

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, JANUARY 2013

IF: 1,969 - Citations: 4 (Scopus); 3 (WoS).

[98] Friligou I, Rizzolo F, Nuti F, Tselios T, Evangelidou M, Emmanouil M, Karamita M, Matsoukas J, Chelli M, Rovero P, Papini AM. Divergent and convergent synthesis of polymannosylated dibranched antigenic peptide of the immunodominant epitope MBP(83-99). Bioorg Med Chem 2013; 21(21):6718-6725. DOI: 10.1016/j.bmc.2013.08.008

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, NOVEMBER 1, 2013

IF: 2,881 - Citations: 8 (Scopus); 8 (WoS).

[99] Candelaresi M, Ragnoni E, Cappelli C, Corozzi A, Lima M, Monti S, Mennucci B, Nuti F, Papini AM, Foggi P. Conformational analysis of Gly-Ala-NHMe in D(2)O and DMSO solutions: a two-dimensional infrared spectroscopy study. J Phys Chem B 2013; 117(46):14226-14237. DOI: 10.1021/jp406139t

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, NOVEMBER 21, 2013

IF: 3,146 - Citations: 3 (Scopus); 3 (WoS).

2014

[100] Naegeli A, Neupert C, Fan YY, Lin CW, Poljak K, Papini AM, Schwarz F, Aebi M. Molecular analysis of an alternative N-glycosylation machinery by functional transfer from Actinobacillus pleuropneumoniae to Escherichia coli. J Biol Chem 2014; 289(4):2170-2179. DOI: 10.1074/jbc.M113.524462

Published by AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3996 USA, JANUARY 24, 2014

IF: 4,011 - Citations: 37 (Scopus); 33 (WoS).

[101] Pratesi A, Gabbiani C, Michelucci E, Ginanneschi M, Papini AM, Rubbiani R, Ott I, Messori L. Insights on the mechanism of thioredoxin reductase inhibition by Gold N-heterocyclic carbene compounds using the synthetic linear Selenocysteine containing C-terminal peptide hTrxR(488-499): An ESI-MS investigation. J Inorg Biochem 2014; 136, 161-169. DOI: 10.1016/j.jinorgbio.2014.01.009

Published by ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA, JULY 2014

IF: 3,063 - Citations: 31 (Scopus); 27 (WoS).

[102] C. Gellini, G. Sabatino, A.M. Papini, M. Muniz-Miranda.SERS study of a tetrapeptide based on histidine and glycine residues, adsorbed on copper/silver colloidal nanoparticles. J Raman Spectrosc2014; 45(6), 418-423. DOI: 10.1002/jrs.4484

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, JUNE 2014

IF: 2,879 - Citations: 6 (Scopus); 6 (WoS).

[103] M. Di Pisa, P. Buccato, G. Sabatino, F. Real Fernández, B. Berti, F. Cocola, A.M. Papini, P. Rovero. Epitope Mapping of the N-terminal Portion of Tissue Transglutaminase Protein Antigen to Identify Linear Epitopes in Celiac Disease. J Pept Sci 2014; 20(9), 689-695. DOI: 10.1002/psc.2650

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, SEPTEMBER 2014

IF: 1,969 - Citations: 4 (Scopus); 3 (WoS).

[104] Papini AM, Nuti F, Real-Fernandez F, Rossi G, Tiberi C, Sabatino G, Pandey S, Leoncini S, Signorini C, Pecorelli A, Guerranti R, Lavielle S, Ciccoli L, Rovero P, De Felice C, Hayek J. Immune dysfunction in Rett syndrome patients revealed by high levels of serum anti-N(Glc) IgM antibody fraction. J Immunol Res 2014:260973. DOI: 10.1155/2014/260973

Published by HINDAWI PUBLISHING CORP, 315 MADISON AVE 3RD FLR, STE 3070, NEW YORK, NY 10017 USA in 2014

IF: 3,298 - Citations: 5 (Scopus); 5 (WoS).

[105] Auberger N, Di Pisa M, Larregola M, Chassaing G, Peroni E, Lavielle S, Papini AM, Lequin O, Mallet JM. Glaser oxidative coupling on peptides: stabilization of β-turn structure via a 1,3-butadiyne constraint. Bioorg Med Chem 2014; 22(24):6924-6932. DOI: 10.1016/j.bmc.2014.10.026

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, DECEMBER 15, 2014

IF: 2,881 - Citations: 9 (Scopus); 8 (WoS).

[106] Testa C, Scrima M, Grimaldi M, D'Ursi AM, Dirain ML, Lubin-Germain N, Singh A, Haskell-Luevano C, Chorev M, Rovero P, Papini AM. 1,4-disubstituted-[1,2,3]triazolyl-containing analogues of MT-II: design, synthesis, conformational analysis, and biological activity. J Med Chem 2014; 57(22):9424-9434. DOI: 10.1021/jm501027w

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA in 2014.

IF: 6,253 - Citations: 24 (Scopus); 27 (WoS).

2015

[107] Kolesinska B, Rozniakowski KK, Fraczyk J, Relich I, Papini AM, Kaminski ZJ. The Effect of Counter-ion and Tertiary Amine on the Efficiency of N-Triazinylammonium Sulfonates in Solution and Solid-Phase Peptide Synthesis. Eur J.O.C. 2015; 2:401-408. DOI: 10.1002/ejoc.201402862

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, JANUARY 2015

IF: 2,882 - Citations: 17 (Scopus); 15 (WoS).

[108] Di Pisa M, Pascarella S, Scrima M, Sabatino G, Real-Fernández F, Chelli M, Renzi D, Calabrò A, D'Ursi AM, Papini AM, Rovero P. Synthetic peptides reproducing tissue transglutaminase-gliadin complex neo-epitopes as probes for antibody detection in celiac disease patients' sera. J Med Chem 2015; 58(3):1390-1399. DOI: 10.1021/jm5017126

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, FEBRUARY 12, 2015

IF: 6,253 - Citations: 4 (Scopus); 3 (WoS).

[109] Smerieri A, Testa C, Lazzeroni P, Nuti F, Grossi E, Cesari S, Montanini L, Latini G, Bernasconi S, Papini AM, Street ME. Di-(2-ethylhexyl) phthalate metabolites in urine show age-related changes and associations with adiposity and parameters of insulin sensitivity in childhood. PLOS One 2015; 10(2):e0117831. DOI: 10.1371/journal.pone.0117831

Published by PUBLIC LIBRARY SCIENCE, 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA, FEBRUARY 23, 2015

IF: 2,766 - Citations: 24 (Scopus); 24 (WoS).

[110] Pratesi A, Ginanneschi M, Melani F, Chinol M, Carollo A, Paganelli G, Lumini M, Bartoli M, Frediani M, Rosi L, Petrucci G, Messori L, Papini AM. Design and solid phase synthesis of new DOTA conjugated (+)-biotin dimers planned to develop molecular weight-tuned avidin oligomers. Org Biomol Chem 2015; 13(13):3988-4001. DOI: 10.1039/c4ob02685c

Published by ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND, 2015

IF: 3,423 - Citations: 2 (Scopus); 1 (WoS).

[111] Rentier C, Monasson O, Nuti F, Rovero P, Sabatino G, Papini AM. Methionine sulfoxide- and sulfone-containing peptide synthesis: management of a relevant post-translational modifications in proteins. Chimica Oggi-Chemistry Today 2015; 33(2S):32-35.

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, MARCH-APRIL 2015

IF: 0,396 - Citations: 0 (WoS).

[112] Rentier C, Pacini G, Nuti F, Peroni E, Rovero P, Papini AM. Synthesis of diastereomerically pure Lys(Nå-lipoyl) building blocks and their use in Fmoc/tBu solid phase synthesis of lipoyl-containing peptides for diagnosis of primary biliary cirrhosis. J Pept Sci 2015; 21(5):408-414. DOI: 10.1002/psc.2761

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, MAY 2015

IF: 1,969 - Citations: 7 (Scopus); 7 (WoS).

[113] Real-Fernández F, Rossi G, Lolli F, Papini AM, Rovero P. Label-free method for anti-glucopeptide antibody detection in Multiple Sclerosis. MethodsX 2015; 2:141-144. DOI: 10.1016/j.mex.2015.03.004

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2015

IF: n.a. - Citations: 5 (Scopus); 5 (WoS).

[114] Real Fernández F, Di Pisa M, Rossi G, Auberger N, Lequin O, Larregola M, Benchohra A, Mansuy C, Chassaing G, Lolli F, Hayek J, Lavielle S, Rovero P, Mallet JM, Papini AM. Antibody recognition in multiple sclerosis and Rett syndrome using a collection of linear and cyclic N-glucosylated antigenic probes. Biopolymers 2015; 104(5):560-576. DOI: 10.1002/bip.22677

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, SEPTEMBER 2015

IF: 1,99 - Citations: 4 (Scopus); 4 (WoS).

[115] Papini AM, König E. Novel diagnostic tools and solutions for multiple sclerosis treatment: a patent review (2009-2014). REVIEW. Expert Opin Ther Pat 2015; 25(8):873-84. DOI: 10.1517/13543776.2015.1043267

Published by TAYLOR & FRANCIS LTD, 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND, AUGUST 2015

IF: 2,867 - Citations: 5 (Scopus); 3 (WoS).

[116] Bellagha-Chenchah W, Sella C, Real Fernandez F, Peroni E, Lolli F, Amatore C, Thouin L, Papini AM. Interactions between Human Antibodies and Synthetic Conformational Peptide Epitopes: Innovative Approach for Electrochemical Detection of Biomarkers of Multiple Sclerosis at Platinum Electrodes. Electrochimica Acta 2015; 176, 1239-1247. DOI: 10.1016/j.electacta.2015.07.158

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 10 SEPTEMBER 2015

IF: 5,116 - Citations: 4 (Scopus); 3 (WoS).

[117] Pacini G, Carotenuto A, Rentier C, Nuti F, Real-Fernandez F, Brancaccio D, Sabatino G, Larregola M, Peroni E, Migliorini P, Novellino E, Battezzati PM, Selmi C, Papini AM, Rovero P. Role of Lipoylation of the Immunodominant Epitope of Pyruvate Dehydrogenase Complex: Toward a Peptide-Based Diagnostic Assay for Primary Biliary Cirrhosis. J Med Chem 2015; 58(16):6619-6629. DOI: 10.1021/acs.jmedchem.5b00783

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, AUGUST 27, 2015

IF: 6,253 - Citations: 2 (Scopus); 2 (WoS).

[118] Real-Fernández F, Cimaz R, Rossi G, Simonini G, Giani T, Pagnini I, Papini AM, Rovero P. Surface plasmon resonance-based methodology for anti-adalimumab antibody identification and kinetic characterization. Anal Bioanal Chem 2015; 407(24):7477-7485. DOI: 10.1007/s00216-015-8915-8

Published by SPRINGER HEIDELBERG, TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY, SEPTEMBER 2015

IF: 3,307 - Citations: 7 (Scopus); 8 (WoS).

[119] Becucci L, Benci S, Nuti F, Real-Fernandez F, Vaezi Z, Stella L, Venanzi M, Rovero P, Papini AM. Interaction Study of Phospholipid Membranes with an N-Glucosylated β-Turn Peptide Structure Detecting Autoantibodies Biomarkers of Multiple Sclerosis. Membranes 2015; 5(4):576-596. DOI: 10.3390/membranes5040576

Published by MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, DECEMBER 2015

IF: n.a. - Citations: 1 (Scopus); 1 (WoS).

2016

[120] Walvoort MT, Testa C, Eilam R, Aharoni R, Nuti F, Rossi G, Real-Fernandez F, Lanzillo R, Brescia Morra V, Lolli F, Rovero P, Imperiali B, Papini AM. Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of non-typeable Haemophilus influenzae. Sci Rep 2016; 6:39430. DOI: 10.1038/srep39430

Published by NATURE PUBLISHING GROUP, MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND, DECEMBER 23, 2016

IF: 4,122 - Citations: 6 (Scopus); 7 (WoS).

[121] Sabatino G, Guryanov I, Rombecchi A, Zanon J, Ricci A, Cabri W, Papini AM, Rovero P. Production of peptides as generic drugs: a patent landscape of octreotide. REVIEW. Expert Opin Ther Pat 2016; 26(4):485-495. DOI: 10.1517/13543776.2016.1158810

Published by TAYLOR & FRANCIS LTD, 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND, APRIL 2, 2016

IF: 2,867 - Citations: 2 (Scopus); 1 (WoS).

[122] De Felice C, Leoncini S, Signorini C, Cortelazzo A, Rovero P, Durand T, Ciccoli L, Papini AM, Hayek J. Rett syndrome: An autoimmune disease? REVIEW. Autoimmunity Reviews 2016; 15(4):411-416. DOI: 10.1016/j.autrev.2016.01.011

Published by ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, APRIL 2016

IF: 8,745 - Citations: 5 (Scopus); 6 (WoS).

[123] Giangrande C, Auberger N, Rentier C, Papini AM, Mallet JM, Lavielle S, Vinh J. Multi-Stage Mass Spectrometry Analysis of Sugar-Conjugated β-Turn Structures to be Used as Probes in Autoimmune Diseases. J Am Soc Mass Spectrom 2016; 27(4):735-747. DOI: 10.1007/s13361-015-1321-9

Published by SPRINGER, 233 SPRING ST, NEW YORK, NY 10013 USA, APRIL 2016

IF: 2,869 - Citations: 2 (Scopus); 1 (WoS).

[124] Pacini G, Ieronymaki M, Nuti F, Sabatino G, Larregola M, Aharoni R, Papini AM, Rovero P. Epitope mapping of anti-myelin oligodendrocyte glycoprotein (MOG) antibodies in a mouse model of multiple sclerosis: microwave-assisted synthesis of the peptide antigens and ELISA screening. J Pept Sci 2016; 22(1):52-58. doi: 10.1002/psc.2839

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, JANUARY 2016

IF: 1,969 - Citations: 3 (Scopus); 3 (WoS).

[125] Pascarella S, Tiberi C, Sabatino G, Nuti F, Papini AM, Giovannelli L, Rovero P. Serpin A1 C-Terminal Peptides as Collagen Turnover Modulators. CHEMMEDCHEM 2016; 11(16):1850-1855. doi: 10.1002/cmdc.201500472

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, AUGUST 19, 2016

IF: 3,009 - Citations: 1 (Scopus); 2 (WoS).

[126] E. Peroni, F. Real Fernández, C. Gheri, F. Nuti, A.-C. Mitaine-Offer, F. Lolli, M.-A. Lacaille-Dubois, A.M. Papini. Natural Triterpene Glycosides for Antibody Recognition. Planta Med Lett 2016; 3(01): e2-e7. DOI: 10.1055/s-0035-1568263

Published by GEORG THIEME VERLAG KG, RUDIGERSTR 14, D-70469 STUTTGART, GERMANY, 2016

IF: n.a.

2017

[127] Champy AS, Mitaine-Offer AC, Miyamoto T, Tanaka C, Papini AM, Lacaille-Dubois MA. Structural analysis of oleanane-type saponins from the roots of Wisteria frutescens. Magn Reson Chem 2017; 55(6), 595-600. DOI: 10.1002/mrc.4550

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, JUNE 2017

IF: 1,776 - Citations: 1 (Scopus); 1 (WoS).

[128] Pratesi A, Ginanneschi M, Lumini M, Papini AM, Novellino E, Brancaccio D, Carotenuto A. DOTA-Derivatives of Octreotide Dicarba-Analogs with High Affinity for Somatostatin sst2,5 Receptors. Front Chem 2017; 5:8. DOI: 10.3389/fchem.2017.00008

Published by FRONTIERS MEDIA SA, AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND, 23 FEBRUARY 2017

IF: 4,155 - Citations: 0 (Scopus); 1 (WoS).

[129] Pratesi A, Stazzoni S, Lumini M, Sabatino G, Carotenuto A, Brancaccio D, Novellino E, Chinol M, Rovero P, Ginanneschi M, Papini AM. Synthesis of dicarba-cyclooctapeptide Somatostatin analogs by conventional and MW-assisted RCM: a study about the impact of the configuration at Cα of selected amino acids. Chemical Engineering & Processing 2017; 122, 365-372. DOI:  10.1016/j.cep.2017.02.005

Published by ELSEVIER SCIENCE SA, PO BOX 564, 1001 LAUSANNE, SWITZERLAND, DECEMBER 2017

IF: 2,826 - Citations: 3 (Scopus); 2 (WoS).

[130] Ieronymaki M, Nuti F, Brancaccio D, Rossi G, Real-Fernández F, Cao Y, Monasson O, Larregola M, Peroni E, Uziel J, Sabatino G, Novellino E, Carotenuto A, Papini AM, Rovero P. Structure-Activity Relationship Studies, SPR Affinity Characterization, and Conformational Analysis of Peptides That Mimic the HNK-1 Carbohydrate Epitope. CHEMMEDCHEM 2017; 12(10):751-759. DOI: 10.1002/cmdc.201700042

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, MAY 22, 2017

IF: 3,009 - Citations: 1 (Scopus); 1 (WoS).

[131] Uber, D; Wyrzykowski, D; Tiberi, C; Sabatino, G; Zmudzinska, W; Chmurzynski, L; Papini, AM; Makowska, J. Conformation-dependent affinity of Cu(II) ions peptide complexes derived from the human Pin1 protein ITC and DSC study. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY 2017; 127:2, 1431-1443. DOI: 10.1007/s10973-016-5387-9

Published by SPRINGER, VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS, FEBRUARY 2017

IF: 2,209 - Citations: 1 (Scopus); 2 (WoS).

[132] Champy AS, Mitaine-Offer AC, Paululat T, Papini AM, Lacaille-Dubois MA. Triterpene Saponins from Wisteria floribunda "macrobotrys" and "rosea". NATURAL PRODUCT COMMUNICATIONS 2017; 12:10, 1573-1576.

Published by NATURAL PRODUCTS INC, 7963 ANDERSON PARK LN, WESTERVILLE, OH 43081 USA, OCTOBER 2017

IF: 0,809 - Citations: 1 (Scopus); 1 (WoS).

2018

[133] Grage SL, Kara S, Bordessa A, Doan V, Rizzolo F, Putzu M, Kubař T, Papini AM, Chaume G, Brigaud T, Afonin S, Ulrich AS. Orthogonal ¹⁸F-labeling for solid-state NMR reveals the conformation and orientation of short peptaibols in membranes. Chem Eur J 2018; 24(17), 4328-4335. DOI: 10.1002/chem.201704307

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, MARCH 20, 2018

IF: 5,16 - Citations: 4 (Scopus); 4 (WoS).

[134] C. Testa, D. D’Addona, M. Scrima, A.M. Tedeschi, A.M. D’Ursi, C. Bernhard, F. Denat, C. Bello, P. Rovero, M. Chorev, A.M. Papini. Design, Synthesis and Conformational Studies of [DOTA]-Octreotide Analogues Containing [1,2,3]Triazolyl as a Disulfide Mimetic. PEPTIDE SCIENCE 2018; 110(5) e24071. DOI: 10.1002/pep2.24071

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, SEPTEMBER 2018

IF: 1,99 - Citations: 0 (Scopus); 0 (WoS).

[135] Kukacka Z, Iurascu M, Lupu L, Rusche H, Murphy M, Altamore L, Borri F, Maeser S, Papini AM, Hennermann J, Przybylski M. Antibody Epitope of human α-Galactosidase A revealed by affinity-mass spectrometry: a basis for reversing immunoreactivity in enzyme replacement therapy of Fabry Disease. CHEMMEDCHEM 2018; 13(9); 909-915. DOI:10.1002/cmdc.201800094

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, MAY 8, 2018

IF: 3,009 - Citations: 0 (Scopus); 0 (WoS).

[136] Becucci L, Aloisi G, Papini AM, Guidelli R. Channel-forming activity of nisin in two mercury-supported biomimetic membranes. JOURNAL OF ELECTROANALYTICAL CHEMISTRY 2018; 812; 186-193. DOI:10.1016/j.jelechem.2017.11.06

Published by ELSEVIER SCIENCE SA, PO BOX 564, 1001 LAUSANNE, SWITZERLAND, MARCH 1, 2018

IF: 3,235 - Citations: 1 (Scopus); 2 (WoS).

[137] Champy-Tixier AS, Mitaine-Offer AC, Real-Fernández F, Miyamoto T, Tanaka C, Papini AM, Lacaille-Dubois MA. Oleanane-type glycosides from the roots of Weigela florida "rumba" and evaluation of their antibody recognition. Fitoterapia 2018; 128:198-203. DOI: 10.1016/j.fitote.2018.04.017

Published by ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, JULY 2018

IF: 2,642 - Citations: 0 (Scopus); 0 (WoS).

[138] C. Testa, A.M. Papini, M. Chorev, P Rovero. Copper-catalyzed azide alkyne cycloaddition (CuAAC)-mediated macrocylization of peptides: impact on conformation and biological activity. REVIEW. Curr Topics Med Chem 2018; 18(7), 591-610. DOI: 10.2174/1568026618666180518095755

Published by BENTHAM SCIENCE PUBL LTD, EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES, in 2018

IF: 3,374 - Citations: 1 (Scopus); 1 (WoS).

[139] M.E. Street, S. Angelini, S. Bernasconi, E. Burgio, A. Cassio, C. Catellani, F. Cirillo, A. Deodati, E. Fabbrizi, V. Fanos, G. Gargano, E. Grossi, L. Iughetti, P. Lazzeroni, A. Mantovani, L. Migliore, P. Palanza, G. Panzica , A.M. Papini, S. Parmigiani, B. Predieri, C. Sartori, G. Tridenti, S. Amarri. Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting. REVIEW. Int J Mol Sci 2018; 19(6):1647. DOI:10.3390/ijms19061647

Published by MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, JUNE 2018

IF: 3,687 - Citations: 5 (Scopus); 2 (WoS).

[140] Nuti F, Gallo A, Real-Fernandez F, Crulli M, Rentier C, Piarulli F, Peroni E, Rossi G, Traldi P, Rovero P, Lapolla A, Papini AM. Antibodies to post-translationally modified mitochondrial peptide PDC-E2(167-184) in type 1 diabetes. Arch Biochem Biophys 2018; 659:66-74. DOI: 10.1016/j.abb.2018.09.021

Published by ELSEVIER SCIENCE INC, STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA, DECEMBER 1, 2018

IF: 3,118 - Citations: 0 (Scopus); 0 (WoS).

[141] A.M. Papini. From morphine to endogenous opioid peptides, e.g., endorphins: the endless quest for the perfect painkiller. Substantia 2018; 2(2): 81-91. DOI: 10.13128/substantia-63

Published by University Press, Firenze, ITALY, SEPTEMBER 24, 2018.

IF: n.a.

2019

[142] Real-Fernández F, Pregnolato F, Cimaz R, Papini AM, Borghi MO, Meroni PL, Rovero P. Detection of anti-adalimumab antibodies in a RA responsive cohort of patients using three different techniques. Analytical Biochemistry 2019; 566, 133-138. DOI: 10.1016/j.ab.2018.11.018

Published by ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA, FEBRUARY 1, 2019

IF: 2,275 - Citations: 0 (Scopus); 0 (WoS).

[143] A. Mazzoleni, J.-M. Mallet, P. Rovero, A.M. Papini. Glycoreplica peptides to investigate molecular mechanisms of immune-mediated physiological versus pathological conditions Arch Biochem Biophys 2019; 663, 44-53. DOI: 10.1016/j.abb.2018.12.030

Published by ELSEVIER SCIENCE INC, STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA, MARCH 15, 2019

IF: 3,118 - Citations: 1 (Scopus); 1 (WoS).

[144] I. Guryanov, F. Real-Fernández, G. Sabatino, N. Prisco, E. Popova, V. Korzhikov-Vlakh, B. Biondi, A.M. Papini, E. Korzhikova-Vlakh, P. Rovero, T. Tennikova. Modeling interaction between gp120 HIV protein and CCR5 receptor. J Pept Sci 2019; 25(2):e3142. DOI: 10.1002/psc.3142

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 24 JANUARY 2019

IF: 1,969 - Citations: 0 (Scopus); 0 (WoS).

[145] C. Bello, P. Rovero, A.M. Papini. Just a spoonful of sugar: short glycans affects protein properties and functions. J Pept Sci 2019; 25(5), e31-67. DOI: 10.1002/psc.3167

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, MAY 2019

IF: 1,969 - Citations: 0 (Scopus); 0 (WoS).

[146] V. Iaconisi, G. Secci, G. Sabatino, G. Piccolo, L. Gasco, A.M. Papini, G. Parisi. Effect of mealworm (Tenebrio molitor L.) larvae meal on amino acid composition of gilthead sea bream (Sparus aurata L.) and rainbow trout (Oncorhynchus mykiss W.) fillets. Aquaculture 2019; 513, 734403. Doi: 10.1016/j.aquaculture.2019.734403

[147] F. Nuti, C. Gellini, M. Larregola, L. Squillantini, R. Chelli, P.R. Salvi, O. Lequin, G. Pietraperzia, A.M. Papini. A photochromic azobenzene peptidomimetic of a β-turn model peptide structure as a conformational switch. Frontiers in Chemistry. Section: Supramolecular Chemistry 2019; 7, Art. 180. DOI: 10.3389/fchem.2019.00180

Published by FRONTIERS MEDIA SA, AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND, MARCH 29, 2019

IF: 4,155 - Citations: 0 (Scopus); 0 (WoS).

[148] De Santis, M; Isailovic, N.; Generali, E.; Ceribelli, A.; Altamore, L.; Real-Fernandez, F.; Papini, A.M.; Rovero, P.; Sabatino, G.; Selmi, C. Humoral response against LL-37 in psoriatic disease: comment on the article by Yuan et al. ARTHRITIS & RHEUMATOLOGY 2019; 71(11), 1964-1965. Published in 2019.

[149] Nuti F, Gallo A, Real-Fernandez F, Rentier C, Rossi G, Piarulli F, Traldi P, Carganico S, Rovero P, Lapolla A, Papini AM. Study of Aberrant Modifications in Peptides as a Test Bench to Investigate the Immunological Response to Non-Enzymatic Glycation. Folia Biol (Praha). 2019;65(4):195-202.

[150] Nguyen DH, Mitaine-Offer AC, Maroso S, Papini AM, Paululat T, Bellaye PS, Collin B, Chambin O, Lacaille-Dubois MA. Cytotoxic glycosides from the roots of Weigela x "Bristol Ruby". Fitoterapia. 2019 Sep;137:104242. doi: 10.1016/j.fitote.2019.104242. Epub 2019 Jun 13.

2020

[151] M. Kijewska, F. Nuti, M. Wierzbicka, M. Waliczek, P. Ledwon, A. Staskiewicz, F. Real-Fernandez, G. Sabatino, P. Rovero, P. Stefanowicz, Z. Szewczuk, A.M. Papini. An Optimised Di-Boronate-ChemMatrix Affinity Chromatography to Trap Deoxyfructosylated Peptides as Biomarkers of Glycation. Molecules 2020, 25, 755. doi:10.3390/molecules25030755

[152] A. D’Ercole, G. Sabatino, L. Pacini, E. Impresari, I. Capecchi, A.M. Papini, P. Rovero. On-resin microwave-assisted copper-catalysed azide-alkyne cycloaddition of H1-relaxin B single chain “stapled” analogues. Peptide Science. Accepted on Feb. 28, 2020.

Patents

[1] “Glycopeptides, their preparation and use in the diagnosis or therapeutic treatment of Multiple Sclerosis”. Inventors: A.M. Papini,P. Rovero, M. Chelli, F. Lolli. Applicant: University of Florence, Italy. PCT (2003) WO 03000733 A2. Italian Patent n. 0001327122 (27/04/2005). Granted USA, Australian and European Patent (02/08/2005). Licensed to IMMCO Diagnostics, Buffalo, USA.

[2] “Immuno-absorption columns for the subtraction of antibodies from blood with selective plasma filtration techniques”. Inventors: F. Pinto, A.M. Papini, M. Chelli, P. Rovero, F. Lolli. Applicant: University of Florence, Italy. PCT International Application (2003) WO 2003009887 Priority Application: IT 2001-FI144.

[3] “Process for the preparation of N-triazinylammonium salts”. Filing date 07/11/2005. Applicant: Italvelluti S.p.a. Inventors: Z. Kaminski, A.M. Papini, B. Kolesinska, J. Kolesinska, K. Jastrzabek, G. Sabatino, R. Bianchini. PCT/EP2005/055793 (2005).

Kaminski, Zbigniew Jerzy; Papini, Anna Maria; Jastrzabek, Konrad; Kolesinska, Beata; Kolesinska, Justyna; Sabatino, Giuseppina; Bianchini, Roberto. Process for the preparation of n-triazinylammonium salts.    PCT Int. Appl.  (2007),     14pp.  CODEN: PIXXD2  WO  2007051496  A1  20070510  AN 2007:511982    CAPLUS. Licensed to ITALVELLUTI (Italy).

[4] “Somatostatin analogues” Filing date 10.03.2005. Applicant: Giuntini Mauro. Inventors: M. Giuntini, M. Ginanneschi, M. Chelli, A.M. Papini. EPC Application (2005) 05101866.1-2401 Priority Application: IT/10.03.04/ITA FI20040057.

Giuntini, Mauro; Ginanneschi, Mauro; Chelli, Mario; Papini, Anna Maria.  Preparation of somatostatin analogues.    Eur. Pat. Appl.  (2005),     10 pp.  CODEN: EPXXDW  EP  1598366  A1  20051123  CAN 144:7091  AN 2005:1235907    CAPLUS

[5] European patent EP2050761 B1, title “Galactosylated peptides, their preparation and use in autoimmune diseases diagnosis”. Inventors: Alcaro M.C.; Chelli M.; Lolli F.; Migliorini P.; Paolini I.; Papini A.M.; Rovero P.

[6] European patent application EP 2284188 A1 - US 2011028409 A1, title “Detection of anti-ribosomal P protein antibodies by means of synthetic peptides”). Inventors: Pratesi F., Alcaro M.C., Chelli M., Fantini P., Lolli F., Paolini I., Papini A.M., Rovero P., Migliorini P. EP09167004.2 (2009). Patent application number EP10168270.6 - PCT/EP2011/061006 (2010). Non exclusive licenses to Theradiag (France), DIESSE (Italy), DIAMETRA (Italy), Amar Immunodiagnostics (India).

[7]"Method for the diagnosis of rheumatoid arthritis". Inventors: Alcaro M.C.; Pratesi F.; Paolini I.; Chelli M.; Lolli F.; Papini A.M.; Rovero P.; Migliorini P. Applicant Toscana Biomarkers Srl. Patent application number EP11167420.6. (2011). Non exclusive licenses to Theradiag (France), DIESSE (Italy), DIAMETRA (Italy), Amar Immunodiagnostics (India).

[8] European patent application EP2402368 A1 - WO2012001103 A1, title "Histone citrullinated peptides and uses thereof". Inventori: Pratesi F., Alcaro M.C., Chelli M., Lolli F., Paolini I., Papini A.M., Rovero P., Migliorini P. Non exclusive licenses to Theradiag (France), DIESSE (Italy), DIAMETRA (Italy), Amar Immunodiagnostics (India).

[9] F. Denat, D. D’Addona, C. Bernhard, A.M. Papini-Rovero, M. Chorev “Clicked somatostatin conjugated analogs for biological applications”. EP 11193530, 14.12.2011. Déposants: Université de Cergy-Pontoise CNRS and Université de Bourgogne.

[10] J. Hayek, C. De Felice, A.M. Papini, P. Rovero, F. Nuti, F. Real-Fernandez, G. Sabatino, C. Tiberi (2012). Nuovi peptidi glicosilati. Azienda Ospedaliera Universitaria Senese. Licensed to Toscana Biomarkers (Italy).

[11] F. Errante, L. Giovannelli, A.M. Papini, P. Rovero. Peptidi bioattivi e composizioni che li contengono. Domanda di brevetto italiano n. 102019000008364 del 07/06/2019. Titolari: Espikem Srl (80%), Università di Firenze (20%)

OTHER PUBLICATIONS (PhD THESIS, NOTES and EDITORIALS)

[1] A.M. Papini. Sintesi di peptidi e loro Studio sotto il Profilo Chimico, Biofarmacologico ed Immunologico. Tesi di Dottorato di Ricerca in Scienze Chimiche (I CICLO INTERNAZIONALE e III CICLO, Borsa Ministero della Pubblica Istruzione); Biblioteche Nazionali di Firenze e Roma (1990) 1-118.

[2] A.M. Papini. Towards peptide-based diagnostics. Chimica Oggi-Chemistry Today 2009; 27(2):2. NOTA.

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, MARCH-APRIL 2009

IF: 0,396 - Citations: 0 (Scopus); 0 (WoS).

[3] A.M. Papini. Cosmetics toward peptide-based cosmeceutics. CHIMICA OGGI-CHEMISTRY TODAY 2010, 28, 6, 3-4. NOTA

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, NOVEMBER-DECEMBER 2010

[4] A.M. Papini. Peptide chemistry revolution. Chimica Oggi-Chemistry Today 2012, 30(2), 22-23. NOTA

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, MARCH-APRIL 2012

[5] Papini AM, Lavielle S, Lubell WD. Co-editors and PIPS organizers. Peptides in Paris. EDITORIALE - SPECIAL ISSUE. Biopolymers 2015; 104(5):v-vii. DOI: 10.1002/bip.22738

IF: 1,99 - Citations: 0 (Scopus); 0 (WoS);

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, SEPTEMBER 2015

[6] A.M. Papini. Meet Our Regional Editor. Protein and Peptide Letters 2017, 24(3), 189. EDITORIALE. Published by Bentham Science Publishers, MARCH 2017.

INVITED LECTURES in UNIVERSITIES, RESEARCH CENTRES AND NATIONAL AND INTERNATIONAL CONGRESSES

Anna Maria Papini

2000-2020

2000

[Inv1] IL1 – 1st Conference “Medicinal Chemistry: Drug Design and Development”, Conference and Cultural Centre, University of Patras (Greece), March 1-3, 2000. March 1, 2000: Lecture invited by the Chair Prof. J. Matsoukas. Title: Synthesis of post-translational modified peptide and non-peptide analogues of MBP/MOG myelin antigens in multiple sclerosis research.

2001

[Inv2] IL2 - 2nd Conference “Medicinal Chemistry: Drug Design and Development”, Conference and Cultural Centre, University of Patras (Greece), March 1-3, 2001. March 1, 2001: Lecture invited by the Chair Prof. J. Matsoukas e Prof. P. Cordopatis. Title: Specific role of Asn(Glc) in autoantibody recognition to glycosylated peptides: towards new immunotherapeutic drugs for the treatment of Multiple Sclerosis.

2002

[Inv3] PL1 - 3rd Conference“Medicinal Chemistry: Drug Design and Development”, Conference and Cultural Centre, University of Patras, Greece, March 7-9, 2002. March 7, 2002: Plenary “Memory Lecture in Honour of Marco Vergelli for his contributions to Multiple Sclerosis Research” invited by the Chairs Prof. J. Matsoukas and Prof. P. Cordopatis. Title: A very promising Cyclic MBP Peptide for Multiple Sclerosis.

[Inv4] PL2 -European Commission-funded Intensive Course: “Synthesis for Solving Biological Problems”,Henderson Hall,Newcastle upon Tyne (United Kingdom), August 3-10, 2002. August 3, 2002: Plenary Lecture invited by the Chair Prof. Bernard Golding. Title: Synthesis of post-translationally modified peptidesof myelin proteins. The contribution of bioorganic chemistry to the diagnosis and immunotherapy of the autoimmune disease multiple sclerosis ».

2003

[Inv5] S1 - Institut de Biologie Moléculaire et Cellulaire, Strasbourg (France). Seminar invited by Dr. Jean-Paul Briand, February 21, 2003, h. 9 :30, Salle des Séminaires. Title: CSF114(Glc): the glycopeptide detecting autoantibodies in multiple sclerosis. MS PepKit, the first diagnostic test to follow-up the disease activity.

[Inv6]: S2- INSERM E209, Hôpital Saint-Antoine, Bâtiment Raoul, Paris (France). Seminar invited by Dr. Claude Carnaud, June 23, 2003. Title: Contribution of peptide chemistry to study the autoimmune disease multiple sclerosis.

[Inv7]: S3- Journée de l’Ecole Doctorale: Du Matériau à l’Interface Chimie-Biologie, Université de Paris-Sud, Bâtiment 338, Paris (France). Seminar invited by Prof. Yves Langlois, September 19, 2003. Title: Contribution de le chimie bioorganique à l’étude d’une pathologie auto-immune: cas de la sclérose en plaque.

[Inv8] S4- 1st Pratical Training Course “Innovative combinatorial approaches and technologies”, ComGenex, Budapest (Hungary) & Polo Scientifico, Università di Firenze, Firenze (Italy), April 9-11, 2003. April 11, 2003: Seminario su invito del Dr. Ferenc Darvas, ComGenex, Budapest. Title: A combinatorial approach for the rational design of innovative diagnostic tools for autoimmune diseases.

[Inv9] IL3 - Italian-German Mini Symposiumon Peptides and Proteins. “Structure and Molecular Recognition”, Max Planck Institut für Biochemie, Kleiner Hoersaal, Bauteil T, Martinsried (Germany). December 5, 2003: Lecture su invito del Prof. Luis Moroder. Title: Development of the innovative designed glycopeptide CSF114(Glc) as prognostic tool for the characterizationof an antibody-mediated multiple sclerosis subgroup.

2004

 [Inv10] IL4 - 5th Conference “Medicinal Chemistry: Drug Design and Development”, Conference and Cultural Centre, University of Patras (Greece), March 11-13, 2004. March 11, 2014: Lecture su invito del Chair Prof. J. Matsoukas. Title: Development of the innovative designed glycopeptide CSF114(Glc), as prognostic tool for the characterization of an antibody-mediated multiple sclerosis subgroup.

[Inv11] IL5 - 9th Naples Workshop, Peptides as Therapeutic, Diagnostics & Vaccines, Villa Orlandi, Anacapri (Italy), May 8-11, 2004. May 9, 2004: Lecture su invito del Chair Prof. Ettore Benedetti. Title: Peptide-based immunoassays for the diagnosis of autoimmune diseases.

[Inv12] S5 - Laboratoire de Synthése et Electrosynthése et Organométalliques UMR CNRS 5188 Faculté des Sciences, Dijon (France), June 11, 2004 : Seminario su invito del Prof. Sylvain Jugé. Title: Solid-phase strategy to cyclic structures.

[Inv13] S6- D.E.A (Diplôme d’Etude Avancés): Microbiologie-Enzymologie-Nutrition (Aspects Moléculaires et Cellulaires), Magistére Microbiologie-Enzymologie (3éme année). Module Biophysique et Biologie Structurale, Université Henry Poincare, Nancy 1, Faculté des Sciences et Techniques, Nancy (France), December 3, 2004 : Seminario su invito del Dr. A. Aubry e dal Prof. B. Vitoux. Title : Peptides portants des modifications post-traductionnelles pour le diagnostic et la thérapie de pathologies autoimmunes.

2005

[Inv14] S7 - Weizmann Institute of Science, Rehovot (Israel), January 18, 2005: Seminario su invito del Prof. M. Sela (Past President del Weizmann Institute e inventore del farmaco Copolymer1. Title: Glycosylated synthetic probes to detect disease-specific autoantibodies, biomarkers of Multiple Sclerosis.

[Inv15] IL6 – 4thEuropean-Japanese Bioorganic Meeting & Chemical Biology COE Program sponsored by Okayama University, Hotel Limani, Ushimado, Setoucvhi, Okayama-Pref. (Japan), March 15-19, 2005. March 17, 2005: Lecture su invito del Prof. Tetsuo Toraya. Title: CSF114(Glc): the first synthetic glycopeptide probe to follow-up disease acrivity in Multiple Sclerosis patients.

[Inv16]S8- Seminaris del Parc Cientific de Barcelona 2005, Universitat de Barcelona (Spain),  May 19, 2005: Seminario su invito del Prof. Fernando Albericio. Titolo: A combinatorial approach for the rational design of innovative prognostic tools for multiple sclerosis.

[Inv17] S9 - Laboratoire de Synthése et Electrosynthése et Organométalliques UMR CNRS 5188 Faculté des Sciences, Dijon (France), May 2, 2005 : Seminario su invito del Prof. Claude Moise. Title: Les bases de la synthése peptidique.

[Inv18] S10 - Conférences de l’Institut de Chimie des Substances Naturelles, CNRS-UPR2301, Bâtiment 27, Gif-sur-Yvette (France), 7 Julliet, 2005 : Seminario su invito del Direttore dell’ICSN Prof. Jean-Yves Lallemand. Title: Les glycopeptides pour le développement de tests prognostiques innovatifs pour suivre la sclérose en plaque: vers un traitement thérapeutique nouveau.

2006

[Inv19]: S11– Doctorate School in Chemical Sciences, Università di Siena. Symposium on Metal Ions and Neurodegeneration,Scientific Campus of S. Miniato, Via A. Moro, Siena Room 14. January 31, 2006: Seminario su invito dellla Prof. Elena Gaggelli a nome del Collegio dei Docenti del Dottorato. Title: Aberrant glucosylation triggering autoimmunity in multiple sclerosis.

[Inv20]IL7- Symposium on Recent Advances in Synthesis and Chemical Biology V. Center for Synthesis and Chemical Biology. O'Flanagan Theatre, Royal College of Surgeons in Ireland (RCSI), Dublin (Ireland), December 15, 2006: Lecture su invito del Prof. Kevin B. Nolan. Title: An Innovative Chemical Reverse Approach to the Discovery of Specific Biomarkers of Autoimmune Diseases.

 [Inv21] IL8 - 7th Conference “Medicinal Chemistry: Drug Design and Design”, Conference and Cultural Centre, University of Patras (Greece), March 8-11, 2006. March 9, 2016: Lecture su invito del Chair Prof. J. Matsoukas. Title: Diagnostics and Prognostic Tools in Multiple Sclerosis.

2007

[Inv22] PL3- Israeli-Italian Bi-National Conference Brain functions: from Basic Reasearch to clinical Applications, Weizmann Institute of Science, Rehovot (Israel), March 14, 2007: Plenary Lecture su invito del Prof. M. Tsodyks. Title: A chemical reverse approach to biomarkers of neurological disorders.

[Inv23]S12- Department of Biological Chemistry, Judea & Samaria College, Ariel (Israel),March 15, 2007:Seminario su invito del Dr. Gary Gellerman. Title: An aberrant N-glucosylation triggering autoimmunity in Multiple Sclerosis from follow-up of disease activity to specific therapeutic treatments.

[Inv24] PL4- The 6^th Congress of the Israeli association for Medicinal Chemistry, Weizmann Institute of Science, Rehovot (Israel), March 18, 2007:First Plenary Lecture su invito del Prof. M. Fridkin. Title: A chemical Reverse Approach to detect biomarkers of autoimmune diseases. Notizia riportata nel Bulletin of the Israel Chemical Society N. 23/January 2008.

[Inv25] S13- Bar-Ilan University, Department of Chemistry,Ramat-Gan (Israel), Special Seminar March 19, 2007:Seminario su invito del Prof. Gerardo Byk. Title: Optimized synthetic strategies to glycopeptides for the development of a diagnostic/prognostic test for Multiple Sclerosis.

[Inv26]S14- Istituto di Biofisica- Unità Operativa di Pisa. Area Ricerca Pisa- S. Cataldo, Pisa (Italy). May, 2, 2007: Seminario su invito del Dr. Santi Chillemi. Title: A chemical reverse approach to decte autoantibodies as biomarkers of autoimmune diseases.

[Inv27] IL9 - Modern Solid Phase Peptide Synthesis & its applications. An official satellite meeting of the 7^th International Australian Peptide Symposium, Port Douglas (Australia), October 17-20, 2007. October 18, 2007: Lecture su invito del Prof. J. Wade. Title: N-Triazinylammonium coupling reagents: from the concept of superactive esters to a versatile assistance for peptide synthesis.

[Inv28]S15 - Howard Florey Institute, University of Melbourne, Melbourne (Australia), October 29, 2007: Seminario su invito del Prof. John Wade. Title: An aberrant N-glucosylation triggering autoimmunity in Multiple Sclerosis: from an efficient follow-up of disease activity to a guide for specific therapeutic treatments.

[Inv29] S16 - Burnet Institute, Austin Campus, Heidelberg (Australia), October 31, 2007. Seminario su invito della Prof. V. Apostolopoulos. Title: Strategies for characterisation of a Multiple Sclerosis pattern disease based on specific autoantibodies as biomarkers.

2008

[Inv30] IL10 - Third ERA Chemistry Flash Conference: Carbohydrates at the interfaces of biology, medicine and materials science. ERA-Chemistry “A Network of research councils for the development and implementation oif joint bottom-up European programmes for curiosity driven research”, Embarkinitiative, Killarney (Ireland), 9-13 March, 2008. March 13, 2008: Lecture su invito del Prof. S. Oscarson e dal Prof. P. Murphy. Title: Aberrant glycosylations as biomarkers of autoimmune diseases correlating with disease activity: toward the development of reliable diagnostic/prognostic tools.

[Inv31] AL1 - 6^th Hellenic Forum on Bioactive Peptides, The Conference and Cultural Centre of the University of Patras (Greece), May 18-20, 2008. May 18, 2008: 1st Dimitrios Theodoropoulos Memorial Lecture Award by the Hellenic Peptide Society to A.M. Papini in recognition of her significant contribution to the advancement of peptide science and especially in peptide chemistry. Title: A “Chemical Reverse Approach” to modified peptides as synthetic antigenic probes to detect autoantibodies as biomarkers of multiple sclerosis.

[Inv32] IL11 - 5th Bulgarian Peptide Symposium, Rila Mountain (Bulgaria), 28-30 May 2008. May 30, 2008:Lecture su invito del Prof. L. Vezenkov. Title: Post-translationally modified peptides to develop reliable diagnostic/prognostic assays to follow up autoimmune diseases.

[Inv33] AL2 - 30th European Peptide Symposium 31 Agosto-5 Settembre  2008, Helsinki (Finland). 31 Agosto 2008: Leonidas Zervas Memorial Lecture Award 2008attributed by the European Peptide Society to A.M. Papini for her outstanding achievements in peptide science (in commemoration of L. Zervas and the outstanding contributions he made to peptide chemistry nominated by the European Peptide Society). Title: Peptide-based immunoassays for biomarkers detection: a challenge for translational research.

[Inv34] S17- Istituto Clinico Humanitas Centro di Ricerca e Didattica, Rozzano, Milano (Italy). December 17, 2008: Seminario su invito del Prof. Carlo Selmi. Title: A Chemical Reverse Approach to Detect Biomarkers of Autoimmune Diseases: a Challenge for Translational Research.

[Inv35] IL12 – 6th International Microwaves in Chemistry Conference, Cambridge Mariott@MIT, Cambridge, MA (USA), May 13-16, 2008. May 14, 2008: Lecture su invito del Prof. Stephen L. Buchwald, Camille Dreyfus Professor. Title: Optrimised strategies for the synthesis of biomolecules: the microwave approach to complex peptides for diagnostic/prognostic immunoassays.

2009

[Inv36] S18 - Barcelona Biomedical Research Park PRBB-CRG Seminar, Pompeu Fabra University, Barcelona (Spain). February 23, 2009: Seminario su invito del Prof. David Andreu.Title: Peptide-based Immunoassays for Biomarkers Detection: a Challenge for Translational Research.

[Inv37] S19 -Master di II livello in “Progettazione e Sviluppo di Farmaci”. Attualità nella Ricerca Farmaceutica Farmaci peptidici e peptoidici. Università degli Studi di Pavia (Italy). April 17, 2009: Lecture su invitodella Prof. Ornella Azzolina.Title: Recenti progressi nella sintesi di peptidi d’interesse biomedico.

[Inv38] PL5 - MAOPS, International Symposium on Microwave-Assisted Organic and Peptide Synthesis 2009, La Grande Motte (France). June 4-5, 2009. June 4, 2009: Plenary Lecture su invito del Dr. Gilles Subra.Title: Optimised strategies for the synthesis of biomolecules: the microwave approach to complex peptides for diagnostics.

[Inv39] PL6 - 11th International Congress on Amino Acids, Peptides and Proteins, Vienna (Austria). August 3-7, 2009. August 6, 2009: Prominent speaker e Plenary Lecture su invito del Prof. Norbert Sewald.Title: Glycated and glycosylated amino acids for Solid-Phase GlycoPeptide Synthesis: a challenge to microwave-assisted strategies for R&D diagnostics of autoimmune diseases.

[Inv40] PL7 – Fundacion BBVA – IRB Barcelona BioMed Conference on “Peptide engineering: Therapeutic peptides”, October 26-28, 2009. October, 28, 2009: Plenary Lecture su invito del Prof. Ernest Giralt e del Prof. Claudio Toniolo.Title: Click chemistry reaction: a challenge for peptide engineering to develop efficient drugs and diagnostics.

[Inv41] IL13 - Does size matter? Beyond small molecule therapeutics: challenges and success stories”, Université Libre de Bruxelles, Salle Dupéel, Avenue Jeanne 44, Brusselles (Belgium). November 6, 2009: Distinguished speaker su invito del Dr. Edmond Differding (President of the Medicinal Chemistry Division, SRC) e del Prof. Koen Augustyns (President, Division for Medicinal and Bioorganic Chemistry, KVCV).Title: Synthetic post-translationally modified peptides for the discovery of new biomarkers of autoimmune diseases: a “Chemical Reverse Approach”.

[Inv42] S20 - Prefectural University of Osaka (Japan). November 12, 2009: Seminario su invito del Prof. Ikuo Fujii.Title: Post-translationally modified peptides for detection of biomarkers of immune-mediated diseases: A “Chemical Reverse Approach”.

2010

[Inv43] PL8 - XII Convegno-Scuola sulla Chimica dei Carboidrati, Gruppo Interdivisionale Chimica dei Carboidrati della S.C.I. Pontignano (Siena). June 20-23, 2010. June 21, 2010: Plenary Lecture su invito del Prof. Michelangelo Parrillo a nome del comitato scientifico. Title: Glycated and glycosylated amino acids for solid-phase glycopeptide synthesis: a challenge for R&D diagnostics of neurodegenerative diseases.

[Inv44] S21 - Université de Versailles, Saint Quentin en Yvelines (France). November 4, 2010: Seminario su invito del Prof. Francois Couty.Title: Chemical approaches to modulate peptide secondary structures inducing specific biological recognition.

[Inv45] IL14 - Juvenil Diabetes Research Foundation Workshop “Role of Beta Cell Antigen Modifications in the Pathogenesis of T1D and their Diagnostic and Therapeutic Potential”,New York (USA). December 13th, 2010: Lecture su invito del Comitato scientifico. Title: A “Chemical Reverse Approach” to detect autoantibodies as biomarkers of autoimmune diseases: a challenge for theragnostics.

2011

[Inv46] S22 - iBiTec-S, CEA/Saclay, Gif sur Yvette (France). January 25, 2011: Seminario su invito del Dr. Bernard Rousseau. Title: Post-translationally modified peptides to characterise specific biomarkers of immune-mediated diseases: a challenge for "theragnostics".

[Inv47] S23 - ICOA - UMR 6005 / Université d'Orléans, Orleans (France). March 30, 2011: Seminario su invito del Prof. Patrick Rollin. Title: Chemical approaches to modulate peptide secondary structures inducing specific biological recognition.

[Inv48] S24- Lezione per il Cycle thématique dell’Université de Cergy-Pontoise "Dynamiques  des systèmes complexes: Modélisation de macromolécules biologiques", St  Martin, Université de Cergy-Pontoise (France).March 31, 2011: invitata dall’organizzatore Prof. Roberto Livi. Title: 3D structures mimicking protein biological activity: from a rational design to peptide-based diagnostics and therapeutics.

[Inv49] S25 - Master 2nd level “Progettazione e Sviluppo di Farmaci: Attualità nella Ricerca Farmaceutica Farmaci peptidici e peptoidici”. Università degli Studi di Pavia, Pavia (Italy). April 15, 2011: Seminario su invito della Prof. Ornella Azzolina.Title: “Approcci sintetici per indurre strutture secondarie e modulare l'attività biologica di peptidi.

[Inv50] S26– Neonatology and beyond, Sala Universitaria - Palazzo Granafei Nervegna, Brindisi (Italy). 14 Maggio 2011: Seminario su invito del Chair Dr. Giuseppe Latini. Title: Ricerca di biomarcatori nelle malattie mediate dal sistema immunitario. Corso di aggiornamento per attribuzione di crediti ECM.

[Inv51] S27- Ecole Doctorale, Université de Montpellier (France). May 26, 2011 : Seminario su invito del Doyen de la Faculté de Pharmacie Prof. Jean Martinez. Title: The importance of a “Chemical Reverse Approach” to modulate peptide secondary structures inducing specific and high affinity biological recognition.

[Inv52] IL15- Italian-German Meeting: Green and SustainableApproach to Process Intensification, Torino (Italy), 2-3 June 2011. June 3, 2011: Lecture su invito del Chair Prof. Giancarlo Cravotto. Title: Efficient synthetic strategies aimed to R&D of diagnostics.

[Inv53] S28INSERM U829, Laboratoire SABNP "Structure-Activité des Biomolécules Normales et Pathologiques" Université d'Evry-Val d'Essonne (France). June 7, 2011: Lecturesu invito del Prof. Flavio Toma. Title : A « Chemical Reverse Approach » to develop efficient diagnostic/prognostic assays for immune-mediated diseases.

[Inv54] IL16- Gordon Research Conference – Carbohydrates, Colby College, Waterville, ME (USA), June 19-24, 2011. June 21, 2011: Lecturesu invito dei Chair Robert J. Woods and Nicola Pohl.Title: The “Chemical Reverse Approach” to develop glycopeptides as synthetic antigens characterising autoantibodies as biomarkers of neurodegenerative diseases. https://www.grc.org/carbohydrates-conference/2011/

[Inv55] S29 - Dipartimento di Scienze della Vita, Università degli Studi di Trieste, Trieste (Italy). July 25, 2011: Seminario su invito delDirettore del Dipartimento di Scienze della Vita Prof. Renato Gennaro.Title: A « Chemical Reverse Approach » to develop efficient and reliable diagnostics for immune-mediated diseases.