Berrino E.; Carradori S.; Angeli A.; Carta F.; Supuran C.T.; Guglielmi P.; Coletti C.; Paciotti R.; Schweikl H.; Maestrelli F.; Cerbai E.; Gallorini M. (2021). Dual carbonic anhydrase ix/xii inhibitors and carbon monoxide releasing molecules modulate LPS-mediated inflammation in mouse macrophages. ANTIOXIDANTS, vol. 10, pp. 1-24, ISSN:2076-3921 DOI  

  Angeli A.; Carta F.; Nocentini A.; Winum J.-Y.; Zalubovskis R.; Onnis V.; Eldehna W.M.; Capasso C.; Carradori S.; Donald W.A.; Dedhar S.; Supuran C.T. (2021). Response to Perspectives on the Classical Enzyme Carbonic Anhydrase and the Search for Inhibitors. BIOPHYSICAL JOURNAL, vol. 120, pp. 178-181, ISSN:0006-3495 DOI  

  Abdelrahman M.A.; Ibrahim H.S.; Nocentini A.; Eldehna W.M.; Bonardi A.; Abdel-Aziz H.A.; Gratteri P.; Abou-Seri S.M.; Supuran C.T. (2021). Novel 3-substituted coumarins as selective human carbonic anhydrase IX and XII inhibitors: Synthesis, biological and molecular dynamics analysis. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 209, pp. 0-0, ISSN:0223-5234 DOI  

  Nocentini, Alessio; Angeli, Andrea; Carta, Fabrizio; Winum, Jean-Yves; Zalubovskis, Raivis; Carradori, Simone; Capasso, Clemente; Donald, William A; Supuran, Claudiu T (2021). Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 36, pp. 561-580, ISSN:1475-6366 DOI  

  Lenci E.; Angeli A.; Calugi L.; Innocenti R.; Carta F.; Supuran C.T.; Trabocchi A. (2021). Multitargeting application of proline-derived peptidomimetics addressing cancer-related human matrix metalloproteinase 9 and carbonic anhydrase II. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 214, pp. 0-0, ISSN:0223-5234 DOI  

  Bonardi Alessandro, Nocentini Alessio, Gratteri Paola, Supuran Claudiu Trandafir (2021). In silico strategies for the rational design, synthesis, and biological evaluation of ligands targeting macromolecules of pharmaceutical interest. (Tutor: Prof.ssa Paola Gratteri, Prof. Claudiu T. Supuran)

  Bouzina A.; Berredjem M.; Nocentini A.; Bua S.; Bouaziz Z.; Jose J.; Le Borgne M.; Marminon C.; Gratteri P.; Supuran C.T. (2021). Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 209, pp. 112875-112882, ISSN:0223-5234 DOI  

  Aspatwar, Ashok; Hammaren, Milka; Parikka, Mataleena; Parkkila, Seppo; Carta, Fabrizio; Bozdag, Murat; Vullo, Daniela; Supuran, Claudiu T (2020). In vitro inhibition of Mycobacterium tuberculosis β-carbonic anhydrase 3 with Mono- and dithiocarbamates and evaluation of their toxicity using zebrafish developing embryos. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 65-71-71, ISSN:1475-6366 DOI  

  Nguyen, Giang T H; Nocentini, Alessio; Angeli, Andrea; Gratteri, Paola; Supuran, Claudiu T; Donald, William A (2020). Perfluoroalkyl Substances of Significant Environmental Concern Can Strongly Inhibit Human Carbonic Anhydrase Isozymes. ANALYTICAL CHEMISTRY, vol. 92, pp. 4614-4622, ISSN:0003-2700 DOI  

  Silvia Peppicelli, Elena Andreucci, Jessica Ruzzolini, Francesca Bianchini, Chiara Nediani, Claudiu T. Supuran, Lido Calorini (2020). The Carbonic Anhydrase IX inhibitor SLC-0111 as emerging agent against the mesenchymal stem cell-derived pro-survival effects on melanoma cells. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 1185-1193, ISSN:1475-6366 DOI  

  Niccolò Chiaramonte, Soumia Maach, Caterina Biliotti, Andrea Angeli, Gian luca Bartolucci, Laura Braconi, Silvia Dei, Elisabetta Teodori, Claudiu T. Supuran, Maria Novella Romanelli (2020). Synthesis and carbonic anhydrase activating properties of a series of 2-amino-imidazolines structurally related to clonidine. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 1003-1010, ISSN:1475-6366 DOI  

  Ceni C.; Catarzi D.; Varano F.; Ben D.D.; Marucci G.; Buccioni M.; Volpini R.; Angeli A.; Nocentini A.; Gratteri P.; Supuran C.T.; Colotta V. (2020). Discovery of first-in-class multi-target adenosine A2A receptor antagonists-carbonic anhydrase IX and XII inhibitors. 8-Amino-6-aryl-2-phenyl-1,2,4-triazolo [4,3-a]pyrazin-3-one derivatives as new potential antitumor agents. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 201, pp. 0-16, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Angeli A.; Ferraroni M.; Pinteala M.; Maier S.S.; Simionescu B.C.; Carta F.; Del Prete S.; Capasso C.; Supuran C.T. (2020). Crystal structure of a tetrameric type II β-carbonic anhydrase from the pathogenic bacterium burkholderia pseudomallei. MOLECULES, vol. 25, pp. 2269-2278, ISSN:1420-3049 DOI  

  Berrino E.; Angeli A.; Zhdanov D.D.; Kiryukhina A.P.; Milaneschi A.; De Luca A.; Bozdag M.; Carradori S.; Selleri S.; Bartolucci G.; Peat T.S.; Ferraroni M.; Supuran C.T.; Carta F. (2020). Azidothymidine "clicked" into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual-Hybrid Inhibitors. JOURNAL OF MEDICINAL CHEMISTRY, vol. 63, pp. 7392-7409, ISSN:0022-2623 DOI  

  Silvia Bua, Alessio Nocentini, Claudiu T. Supuran, Silvia Selleri (2020). Hybrid Pharmacophores as Carbonic Anhydrase Inhibitors. (Tutor: Claudiu T. Supuran, Silvia Selleri)

  Sharma V.; Kumar R.; Angeli A.; Supuran C.T.; Sharma P.K. (2020). Tail approach synthesis of novel benzenesulfonamides incorporating 1,3,4-oxadiazole hybrids as potent inhibitor of carbonic anhydrase I, II, IX, and XII isoenzymes. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 193, pp. 112219-112219, ISSN:0223-5234 DOI  

  Angeli, Andrea; Carta, Fabrizio; Donnini, Selene; Capperucci, Antonella; Ferraroni, Marta; Tanini, Damiano; Supuran, Claudiu T (2020). Selenolesterase enzyme activity of carbonic anhydrases. CHEMICAL COMMUNICATIONS, pp. 0-0, ISSN:1359-7345 DOI  

  Thacker P.S.; Angeli A.; Argulwar O.S.; Tiwari P.L.; Arifuddin M.; Supuran C.T. (2020). Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. BIOORGANIC CHEMISTRY, vol. 98, pp. 103739-103739, ISSN:0045-2068 DOI  

  Angeli A.; Prete S.D.; Ghobril C.; Hitce J.; Clavaud C.; Marrat X.; Donald W.A.; Capasso C.; Supuran C.T. (2020). Activation studies of the β-carbonic anhydrases from Malassezia restricta with amines and amino acids. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 824-830, ISSN:1475-6366 DOI  

  Mancuso F.; Di Fiore A.; De Luca L.; Angeli A.; Monti S.M.; De Simone G.; Supuran C.T.; Gitto R. (2020). Looking toward the Rim of the Active Site Cavity of Druggable Human Carbonic Anhydrase Isoforms. ACS MEDICINAL CHEMISTRY LETTERS, pp. 0-0, ISSN:1948-5875 DOI  

  Manasa, Kesari Lakshmi; Pujitha, Sravya; Sethi, Aaftaab; Mohammed, Arifuddin; Alvala, Mallika; Angeli, Andrea; Supuran, Claudiu T (2020). Synthesis and Biological Evaluation of Imidazo[2 ,1-b]Thiazole based Sulfonyl Piperazines as Novel Carbonic Anhydrase II Inhibitors. METABOLITES, vol. 10, pp. 136-136, ISSN:2218-1989 DOI  

  Angeli, Andrea; Etxebeste-Mitxeltorena, Mikel; Sanmartín, Carmen; Espuelas, Socorro; Moreno, Esther; Azqueta, Amaya; Parkkila, Seppo; Carta, Fabrizio; Supuran, Claudiu T (2020). Tellurides Bearing Sulfonamides as Novel Inhibitors of Leishmanial Carbonic Anhydrase with Potent Antileishmanial Activity. JOURNAL OF MEDICINAL CHEMISTRY, pp. 0-0, ISSN:0022-2623 DOI  

  Pratesi, Debora; Matassini, Camilla; Goti, Andrea; Angeli, Andrea; Carta, Fabrizio; Supuran, Claudiu T.; Spanevello, Rolando; Cardona, Francesca (2020). Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors. ACS MEDICINAL CHEMISTRY LETTERS, vol. 11, pp. 727-731, ISSN:1948-5875 DOI  

  Ali, Majid; Bozdag, Murat; Farooq, Umar; Angeli, Andrea; Carta, Fabrizio; Berto, Paola; Zanotti, Giuseppe; Supuran, Claudiu T (2020). Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 21, pp. 2560-2560, ISSN:1422-0067 DOI  

  Scheila Daiane Schmidt, Alessia Costa, Barbara Rani, Eduarda Godfried Nachtigall, Maria Beatrice Passani, Fabrizio Carta, Alessio Nocentini, Jociane de Carvalho Myskiw, Cristiane Regina Guerino Furini, Claudiu T. Supuran, Ivan Izquierdo, Patrizio Blandina, Gustavo Provensi (2020). The role of carbonic anhydrases in extinction of contextual fear memory. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, pp. 1-9, ISSN:0027-8424 DOI  

  Patrizio Blandina, Gustavo Provensi, Maria Beatrice Passani, Clemente Capasso, Claudiu T. Supuran (2020). Carbonic anhydrase modulation of emotional memory. Implications for the treatment of cognitive disorders. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 1206-1214, ISSN:1475-6374 DOI  

  D'Ascenzio M.; Secci D.; Carradori S.; Zara S.; Guglielmi P.; Cirilli R.; Pierini M.; Poli G.; Tuccinardi T.; Angeli A.; Supuran C.T. (2020). 1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors. JOURNAL OF MEDICINAL CHEMISTRY, vol. 63, pp. 2470-2488, ISSN:0022-2623 DOI  

  Angeli A.; Peat T.S.; Selleri S.; Saleh Alfawaz Altamimi A.; Supuran C.T.; Carta F. (2020). X-ray crystallography of Epacadostat in adduct with Carbonic Anhydrase IX. BIOORGANIC CHEMISTRY, vol. 97, pp. 103669-103669, ISSN:0045-2068 DOI  

  Zoppi C.; Nocentini A.; Supuran C.T.; Pratesi A.; Messori L. (2020). Native mass spectrometry of human carbonic anhydrase I and its inhibitor complexes. JBIC, pp. 1-15, ISSN:0949-8257 DOI  

  Luchinat E.; Barbieri L.; Cremonini M.; Nocentini A.; Supuran C.T.; Banci L. (2020). Drug Screening in Human Cells by NMR Spectroscopy Allows the Early Assessment of Drug Potency. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 59, pp. 6535-6539, ISSN:1433-7851 DOI   Accesso ONLINE all'editore

  Ruzzolini J, Laurenzana A, Andreucci E, Peppicelli S, Bianchini F, Carta F, Supuran CT, Romanelli MN, Nediani C, Calorini L. (2020). A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 391-397, ISSN:1475-6366 DOI  

  Vistoli, Giulio; Aldini, Giancarlo; Fumagalli, Laura; Dallanoce, Clelia; Angeli, Andrea; Supuran, Claudiu T. (2020). Activation Effects of Carnosine- and Histidine-Containing Dipeptides on Human Carbonic Anhydrases: A Comprehensive Study. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 21, pp. 1761-1761, ISSN:1422-0067 DOI  

  Meleddu R.; Distinto S.; Cottiglia F.; Angius R.; Caboni P.; Angeli A.; Melis C.; Deplano S.; Alcaro S.; Ortuso F.; Supuran C.T.; Maccioni E. (2020). New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII. ACS MEDICINAL CHEMISTRY LETTERS, pp. 0-0, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Emanuela Berrino, Claudiu Supuran, Alessandro Mugelli, Fabrizio Carta (2020). Carbonic Anhydrase Inhibitors: Versatile Agents for the Treatment of Human Diseases. (Tutor: Claudiu Supuran, Alessandro Mugelli)

  Luchinat, Enrico; Barbieri, Letizia; Cremonini, Matteo; Nocentini, Alessio; Supuran, Claudiu T; Banci, Lucia (2020). Intracellular Binding/Unbinding Kinetics of Approved Drugs to Carbonic Anhydrase II Observed by in-Cell NMR. ACS CHEMICAL BIOLOGY, vol. 15, pp. 2792-2800-2800, ISSN:1554-8929 DOI  

  Fois, Benedetta; Distinto, Simona; Meleddu, Rita; Deplano, Serenella; Maccioni, Elias; Floris, Costantino; Rosa, Antonella; Nieddu, Mariella; Caboni, Pierluigi; Sissi, Claudia; Angeli, Andrea; Supuran, Claudiu T; Cottiglia, Filippo (2020). Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 539-548-548, ISSN:1475-6366 DOI  

  Kucukbay H.; Bugday N.; Kucukbay F.Z.; Ageli A.; Bartolucci G.; Supuran C.T. (2020). Synthesis and human carbonic anhydrase I, II, VA, and XII inhibition with novel amino acid–sulphonamide conjugates. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 489-497, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Pinteala, Mariana; Maier, Stelian S; Simionescu, Bogdan C; Milaneschi, Andrea; Abbas, Ghulam; Del Prete, Sonia; Capasso, Clemente; Capperucci, Antonella; Tanini, Damiano; Carta, Fabrizio; Supuran, Claudiu T (2020). Evaluation of Thio- and Seleno-Acetamides Bearing Benzenesulfonamide as Inhibitor of Carbonic Anhydrases from Different Pathogenic Bacteria. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 21, pp. 598-598, ISSN:1422-0067 DOI  

  Del Prete, Sonia; Angeli, Andrea; Ghobril, Cynthia; Hitce, Julien; Clavaud, Cécile; Marat, Xavier; Supuran, Claudiu T; Capasso, Clemente (2020). Sulfonamide Inhibition Profile of the β-Carbonic Anhydrase from Malassezia restricta, An Opportunistic Pathogen Triggering Scalp Conditions. METABOLITES, vol. 10, pp. 39-39, ISSN:2218-1989 DOI  

  Teodori E.; Braconi L.; Bua S.; Lapucci A.; Bartolucci G.; Manetti D.; Romanelli M.N.; Dei S.; Supuran C.T.; Coronnello M. (2020). Dual P-glycoprotein and CA XII inhibitors: A new strategy to reverse the P-gp Mediated Multidrug Resistance (MDR) in cancer cells y. MOLECULES, vol. 25, pp. 1-26, ISSN:1420-3049 DOI   Accesso ONLINE all'editore

  La Regina G.; Puxeddu M.; Nalli M.; Vullo D.; Gratteri P.; Supuran C.T.; Nocentini A.; Silvestri R. (2020). Discovery of New 1,1′-Biphenyl-4-sulfonamides as Selective Subnanomolar Human Carbonic Anhydrase II Inhibitors. ACS MEDICINAL CHEMISTRY LETTERS, vol. 11, pp. 633-637, ISSN:1948-5875 DOI  

  Akgul O.; Singh S.; Andring J.T.; McKenna R.; Selleri S.; Carta F.; Angeli A.; Supuran C.T. (2020). Handling drug-target selectivity: A study on ureido containing Carbonic Anhydrase inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, pp. 0-0, ISSN:0223-5234 DOI  

  Kucukbay H.; Gonul Z.; Kucukbay F.Z.; Angeli A.; Bartolucci G.; Supuran C.T. (2020). Preparation, carbonic anhydrase enzyme inhibition and antioxidant activity of novel 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives incorporating mono or dipeptide moiety. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 1021-1026, ISSN:1475-6366 DOI  

  Costa G.; Maruca A.; Rocca R.; Ambrosio F.A.; Berrino E.; Carta F.; Mesiti F.; Salatino A.; Lanzillotta D.; Trapasso F.; Artese A.; Alcaro S.; Supuran C.T. (2020). In silico identification and biological evaluation of antioxidant food components endowed with IX and XII hCA inhibition. ANTIOXIDANTS, vol. 9, pp. 1-13, ISSN:2076-3921 DOI  

  Aspatwar A.; Berrino E.; Bua S.; Carta F.; Capasso C.; Parkkila S.; Supuran C.T. (2020). Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 1765-1772, ISSN:1475-6366 DOI  

  Bozdag M.; Supuran C.T.; Esposito D.; Angeli A.; Carta F.; Monti S.M.; De Simone G.; Alterio V. (2020). 2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site. CHEMICAL COMMUNICATIONS, vol. 56, pp. 8297-8300, ISSN:1359-7345 DOI  

  Akgul O.; Angeli A.; Vullo D.; Carta F.; Supuran C.T. (2020). Unconventional amino acids in medicinal chemistry: First report on taurine merged within carbonic anhydrase inhibitors. BIOORGANIC CHEMISTRY, vol. 103, pp. 0-0, ISSN:0045-2068 DOI  

  Mori M.; Capasso C.; Carta F.; Donald W.A.; Supuran C.T. (2020). A deadly spillover: SARS-CoV-2 outbreak. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 30, pp. 481-485, ISSN:1354-3776 DOI  

  Ali M.; Angeli A.; Bozdag M.; Carta F.; Capasso C.; Farooq U.; Supuran C.T. (2020). Benzylaminoethylureido-Tailed Benzenesulfonamides Show Potent Inhibitory Activity against Bacterial Carbonic Anhydrases. CHEMMEDCHEM, pp. 0-0, ISSN:1860-7179 DOI  

  Poli G.; Bozdag M.; Berrino E.; Angeli A.; Tuccinardi T.; Carta F.; Supuran C.T. (2020). N-aryl-N′-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions. BIOORGANIC CHEMISTRY, vol. 100, pp. 0-0, ISSN:0045-2068 DOI  

  Angeli A.; Carta F.; Nocentini A.; Winum J.-Y.; Zalubovskis R.; Akdemir A.; Onnis V.; Eldehna W.M.; Capasso C.; Simone G.D.; Monti S.M.; Carradori S.; Donald W.A.; Dedhar S.; Supuran C.T. (2020). Carbonic anhydrase inhibitors targeting metabolism and tumor microenvironment. METABOLITES, vol. 10, pp. 1-21, ISSN:2218-1989 DOI  

  Lucarini L.; Durante M.; Sgambellone S.; Lanzi C.; Bigagli E.; Akgul O.; Masini E.; Supuran C.T.; Carta F. (2020). Effects of new nsaid-cai hybrid compounds in inflammation and lung fibrosis. BIOMOLECULES, vol. 10, pp. 1-20, ISSN:2218-273X DOI  

  Guglielmi P.; Rotondi G.; Secci D.; Angeli A.; Chimenti P.; Nocentini A.; Bonardi A.; Gratteri P.; Carradori S.; Supuran C.T. (2020). Novel insights on saccharin- and acesulfame-based carbonic anhydrase inhibitors: design, synthesis, modelling investigations and biological activity evaluation. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 1891-1905, ISSN:1475-6366 DOI  

  Clima L.; Craciun B.F.; Angeli A.; Petreni A.; Bonardi A.; Nocentini A.; Carta F.; Gratteri P.; Pinteala M.; Supuran C.T. (2020). Synthesis, Computational Studies and Assessment of in Vitro Activity of Squalene Derivatives as Carbonic Anhydrase Inhibitors. CHEMMEDCHEM, vol. 15, pp. 2052-2057, ISSN:1860-7179 DOI  

  Bonardi A.; Nocentini A.; Bua S.; Combs J.; Lomelino C.; Andring J.; Lucarini L.; Sgambellone S.; Masini E.; McKenna R.; Gratteri P.; Supuran C.T. (2020). Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action. JOURNAL OF MEDICINAL CHEMISTRY, vol. 63, pp. 7422-7444, ISSN:0022-2623 DOI  

  Alkhaldi A.A.M.; Al-Sanea M.M.; Nocentini A.; Eldehna W.M.; Elsayed Z.M.; Bonardi A.; Abo-Ashour M.F.; El-Damasy A.K.; Abdel-Maksoud M.S.; Al-Warhi T.; Gratteri P.; Abdel-Aziz H.A.; Supuran C.T.; El-Haggar R. (2020). 3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 207, pp. 0-0, ISSN:0223-5234 DOI  

  Nocentini A.; Alterio V.; Bua S.; Micheli L.; Esposito D.; Buonanno M.; Bartolucci G.; Osman S.M.; Alothman Z.A.; Cirilli R.; Pierini M.; Monti S.M.; Di Cesare Mannelli L.; Gratteri P.; Ghelardini C.; De Simone G.; Supuran C.T. (2020). Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy. JOURNAL OF MEDICINAL CHEMISTRY, vol. 63, pp. 5185-5200, ISSN:0022-2623 DOI  

  Bua S.; Lucarini L.; Micheli L.; Menicatti M.; Bartolucci G.; Selleri S.; Di Cesare Mannelli L.; Ghelardini C.; Masini E.; Carta F.; Gratteri P.; Nocentini A.; Supuran C.T. (2020). Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis. JOURNAL OF MEDICINAL CHEMISTRY, vol. 63, pp. 2325-2342, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Felipe Raposo Passos Mansoldo; Fabrizio Carta; Andrea Angeli; Veronica da Silva Cardoso; Claudiu T. Supuran; Alane Beatriz Vermelho (2020). Chagas Disease: Perspectives on the Past and Present and Challenges in Drug Discovery. MOLECULES, vol. 25, pp. 0-0, ISSN:1420-3049 DOI  

  Pustenko A.; Nocentini A.; Gratteri P.; Bonardi A.; Vozny I.; Zalubovskis R.; Supuran C.T. (2020). The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 1011-1020, ISSN:1475-6366 DOI  

  Said M.A.; Eldehna W.M.; Nocentini A.; Bonardi A.; Fahim S.H.; Bua S.; Soliman D.H.; Abdel-Aziz H.A.; Gratteri P.; Abou-Seri S.M.; Supuran C.T. (2020). Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 185, pp. 1-13, ISSN:0223-5234 DOI  

  Hargunani P.; Tadge N.; Ceruso M.; Leitans J.; Kazaks A.; Tars K.; Gratteri P.; Supuran C.T.; Nocentini A.; Toraskar M.P. (2020). Aryl-4,5-dihydro-1H-pyrazole-1-carboxamide derivatives bearing a sulfonamide moiety show single-digit nanomolar-to-subnanomolar inhibition constants against the tumor-associated human carbonic anhydrases IX and XII. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 21, pp. 1-11, ISSN:1661-6596 DOI  

  Angeli A.; Pinteala M.; Maier S.S.; Simionescu B.C.; Da'dara A.A.; Skelly P.J.; Supuran C.T. (2020). Sulfonamide inhibition studies of an α-carbonic anhydrase from Schistosoma mansoni, a platyhelminth parasite responsible for schistosomiasis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 21, pp. 1842-1850, ISSN:1661-6596 DOI  

  Krasavin M.; Kalinin S.; Zozulya S.; Gryniukova A.; Borysko P.; Angeli A.; Supuran C.T. (2020). Screening of benzenesulfonamide in combination with chemically diverse fragments against carbonic anhydrase by differential scanning fluorimetry. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 306-310, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Llanos M.A.; Sbaraglini M.L.; Villalba M.L.; Ruiz M.D.; Carrillo C.; Soto C.A.; Talevi A.; Angeli A.; Parkkila S.; Supuran C.T.; Gavernet L. (2020). A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 21-30, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Krasavin M.; Kalinin S.; Zozulya S.; Griniukova A.; Borysko P.; Angeli A.; Supuran C.T. (2020). Further validation of strecker-type α-aminonitriles as a new class of potent human carbonic anhydrase II inhibitors: hit expansion within the public domain using differential scanning fluorimetry leads to chemotype refinement. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 165-171, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Angeli A.; Carta F.; Supuran C.T. (2020). Carbonic anhydrases: Versatile and useful biocatalysts in chemistry and biochemistry. CATALYSTS, vol. 10, pp. 1-11, ISSN:2073-4344 DOI  

  Said M.A.; Eldehna W.M.; Nocentini A.; Fahim S.H.; Bonardi A.; Elgazar A.A.; Krystof V.; Soliman D.H.; Abdel-Aziz H.A.; Gratteri P.; Abou-Seri S.M.; Supuran C.T. (2020). Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 189, pp. 1-14, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Andreucci, Elena; Ruzzolini, Jessica; Peppicelli, Silvia; Bianchini, Francesca; Laurenzana, Anna; Carta, Fabrizio; Supuran, Claudiu T.; Calorini, Lido (2019). The carbonic anhydrase IX inhibitor SLC-0111 sensitises cancer cells to conventional chemotherapy. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34, pp. 117-123, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Thacker P.S.; Alvala M.; Arifuddin M.; Angeli A.; Supuran C.T. (2019). Design, synthesis and biological evaluation of coumarin-3-carboxamides as selective carbonic anhydrase IX and XII inhibitors. BIOORGANIC CHEMISTRY, vol. 86, pp. 386-392, ISSN:0045-2068 DOI  

  Küçükbay, Hasan*; Buğday, Nesrin; Küçükbay, F. Zehra; Berrino, Emanuela; Bartolucci, Gian Luca; Del Prete, Sonia; Capasso, Clemente; Supuran, Claudiu T. (2019). Synthesis and carbonic anhydrase inhibitory properties of novel 4-(2-aminoethyl)benzenesulfonamide-dipeptide conjugates. BIOORGANIC CHEMISTRY, vol. 83, pp. 414-423, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Bozdag, Murat; Altamimi, Abdulmalik Saleh Alfawaz; Vullo, Daniela; Supuran, Claudiu T; Carta, Fabrizio (2019). State of the Art on Carbonic Anhydrase Modulators for Biomedical Purposes. CURRENT MEDICINAL CHEMISTRY, vol. 26, pp. 2558-2573, ISSN:0929-8673 DOI  

  Micheli L.; Bozdag M.; Akgul O.; Carta F.; Guccione C.; Bergonzi M.C.; Bilia A.R.; Cinci L.; Lucarini E.; Parisio C.; Supuran C.T.; Ghelardini C.; Di Cesare Mannelli L. (2019). Pain relieving effect of-NSAIDS-CAIs hybrid molecules: Systemic and intra-articular treatments against rheumatoid arthritis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, pp. 1923-1938, ISSN:1422-0067 DOI   Accesso ONLINE all'editore

  Al-Tamimi A.-M.S.; Etxebeste-Mitxeltorena M.; Sanmartin C.; Jimenez-Ruiz A.; Syrjanen L.; Parkkila S.; Selleri S.; Carta F.; Angeli A.; Supuran C.T. (2019). Discovery of new organoselenium compounds as antileishmanial agents. BIOORGANIC CHEMISTRY, vol. 86, pp. 339-345, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Angeli A.; Di Cesare Mannelli L.; Ghelardini C.; Peat T.S.; Bartolucci G.; Menicatti M.; Carta F.; Supuran C.T. (2019). Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 177, pp. 188-197, ISSN:1768-3254 DOI   Accesso ONLINE all'editore

  Eysteinsson T.; Gudmundsdottir H.; Hardarson A.O.; Berrino E.; Selleri S.; Supuran C.T.; Carta F. (2019). Carbonic anhydrase inhibitors of different structures dilate pre-contracted porcine retinal arteries. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, pp. 467-479, ISSN:1661-6596 DOI   Accesso ONLINE all'editore

  Bozdag M.; Poli G.; Angeli A.; Lucarini E.; Tuccinardi T.; Di Cesare Mannelli L.; Selleri S.; Ghelardini C.; Winum J.-Y.; Carta F.; Supuran C.T. (2019). N-aryl-N’-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties. BIOORGANIC CHEMISTRY, vol. 89, pp. 103033-103043, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Tanini, Damiano; Ricci, Lorenzo; Capperucci, Antonella; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Peat, Thomas S; Carta, Fabrizio; Angeli, Andrea; Supuran, Claudiu T (2019). Synthesis of novel tellurides bearing benzensulfonamide moiety as carbonic anhydrase inhibitors with antitumor activity. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 181, pp. 111586-111594, ISSN:1768-3254 DOI  

  Bozdag, Murat; Ferraroni, Marta; Ward, Carol; Carta, Fabrizio; Bua, Silvia; Angeli, Andrea; Langdon, Simon P; Kunkler, Ian H; Al-Tamimi, Abdul-Malek S; Supuran, Claudiu T (2019). Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 182, pp. 111600-111611, ISSN:1768-3254 DOI  

  Berrino E.; Milazzo L.; Micheli L.; Vullo D.; Angeli A.; Bozdag M.; Nocentini A.; Menicatti M.; Bartolucci G.; Di Cesare Mannelli L.; Ghelardini C.; Supuran C.T.; Carta F. (2019). Synthesis and evaluation of carbonic anhydrase inhibitors with carbon monoxide releasing properties for the management of rheumatoid arthritis. JOURNAL OF MEDICINAL CHEMISTRY, vol. 62, pp. 7233-7249, ISSN:1520-4804 DOI  

  Damiano Tanini, Antonella Capperucci, Claudiu T. Supuran, Andrea Angeli (2019). Sulfur, selenium and tellurium containing amines act as effective carbonic anhydrase activators. BIOORGANIC CHEMISTRY, vol. 87, pp. 516-523, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Tanini D.; Capperucci A.; Scopelliti M.; Milaneschi A.; Angeli A.; Supuran C.T. (2019). Syntesis of thio- and seleno-acetamides bearing benzenesulfonamide as potent inhibitors of human carbonic anhydrase II and XII. BIOORGANIC CHEMISTRY, vol. 89, pp. 102984-102984, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Kalisha Vali Y.; Gundla R.; Singh O.V.; Tamboli Y.; Di Cesare Manelli L.; Ghelardini C.; Al-Tamimi A.-M.S.; Carta F.; Angeli A.; Supuran C.T. (2019). Spirocyclic sulfonamides with carbonic anhydrase inhibitory and anti-neuropathic pain activity. BIOORGANIC CHEMISTRY, vol. 92, pp. 103210-103220, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Carta, Fabrizio; Dumy, Pascal; Supuran, Claudiu T; Winum, Jean-Yves (2019). Multivalent Carbonic Anhydrases Inhibitors. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, pp. 5352-5367, ISSN:1422-0067 DOI  

  Supuran C.T.; Altamimi A.S.A.; Carta F. (2019). Carbonic anhydrase inhibition and the management of glaucoma: a literature and patent review 2013-2019. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 29, pp. 781-792, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  Kalinin, Stanislav; Nocentini, Alessio; Kovalenko, Alexander; Sharoyko, Vladimir; Bonardi, Alessandro; Angeli, Andrea; Gratteri, Paola; Tennikova, Tatiana B.; Supuran, Claudiu T.; Krasavin, Mikhail (2019). From random to rational: A discovery approach to selective subnanomolar inhibitors of human carbonic anhydrase IV based on the Castagnoli-Cushman multicomponent reaction. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 182, pp. 111642-111660, ISSN:1768-3254 DOI  

  De Simone, Giuseppina; Di Fiore, Anna; Truppo, Emanuela; Langella, Emma; Vullo, Daniela; Supuran, Claudiu T; Monti, Simona Maria (2019). Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34, pp. 1506-1510-1510, ISSN:1475-6366 DOI  

  Eldehna, Wagdy M.*; Abo-Ashour, Mahmoud F.; Nocentini, Alessio; El-Haggar, Radwan S.; Bua, Silvia; Bonardi, Alessandro; Al-Rashood, Sara T.; Hassan, Ghada S.; Gratteri, Paola; Abdel-Aziz, Hatem A.; Supuran, Claudiu T. (2019). Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 162, pp. 147-160, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Nocentini, Alessio; Gratteri, Paola*; Supuran, Claudiu T. (2019). Phosphorus versus Sulfur: Discovery of Benzenephosphonamidates as Versatile Sulfonamide-Mimic Chemotypes Acting as Carbonic Anhydrase Inhibitors. CHEMISTRY-A EUROPEAN JOURNAL, vol. 25, pp. 1188-1192, ISSN:0947-6539 DOI   Accesso ONLINE all'editore

  Bonardi, Alessandro; Vermelho, Alane Beatriz; Da Silva Cardoso, Veronica; De Souza Pereira, Mirian Claudia; Da Silva Lara, Leonardo; Selleri, Silvia; Gratteri, Paola; Supuran, Claudiu T.; Nocentini, Alessio (2019). N-Nitrosulfonamides as Carbonic Anhydrase Inhibitors: A Promising Chemotype for Targeting Chagas Disease and Leishmaniasis. ACS MEDICINAL CHEMISTRY LETTERS, vol. 10, pp. 413-418, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Tanini, Damiano; Nocentini, Alessio; Capperucci, Antonella; Ferraroni, Marta; Gratteri, Paola; Supuran, Claudiu T.* (2019). Selenols: a new class of carbonic anhydrase inhibitors. CHEMICAL COMMUNICATIONS, vol. 55, pp. 648-651, ISSN:1359-7345 DOI   Accesso ONLINE all'editore

  Niccolò Chiaramontea, Silvia Bua, Andrea Angeli, Marta Ferraroni, Ilaria Picchioni, Gianluca Bartolucci, Laura Braconi, Silvia Dei, Elisabetta Teodori, Claudiu T. Supuran, Maria Novella Romanelli (2019). Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors. BIOORGANIC CHEMISTRY, vol. 91, pp. 1-11, ISSN:0045-2068 DOI  

  Eldehna W.M.; Abdelrahman M.A.; Nocentini A.; Bua S.; Al-Rashood S.T.; Hassan G.S.; Bonardi A.; Almehizia A.A.; Alkahtani H.M.; Alharbi A.; Gratteri P.; Supuran C.T. (2019). Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5(4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX inhibitors endowed with anticancer activity. BIOORGANIC CHEMISTRY, vol. 90, pp. 103102-103111, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Nocentini A.; Osman S.M.; Almeida I.A.; Cardoso V.; Alasmary F.A.S.; AlOthman Z.; Vermelho A.B.; Gratteri P.; Supuran C.T. (2019). Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34 (1), pp. 1164-1171, ISSN:1475-6366, TAYLOR & FRANCIS LTD: DOI   Accesso ONLINE all'editore

  Abdelrahman M.A.; Eldehna W.M.; Nocentini A.; Bua S.; Al-Rashood S.T.; Hassan G.S.; Bonardi A.; Almehizia A.A.; Alkahtani H.M.; Alharbi A.; Gratteri P.; Supuran C.T. (2019). Novel diamide-based benzenesulfonamides as selective carbonic anhydrase ix inhibitors endowed with antitumor activity: Synthesis, biological evaluation and in silico insights. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, pp. 2484-2499, ISSN:1661-6596 DOI   Accesso ONLINE all'editore

  Vats L.; Kumar R.; Bua S.; Nocentini A.; Gratteri P.; Supuran C.T.; Sharma P.K. (2019). Continued exploration and tail approach synthesis of benzenesulfonamides containing triazole and dual triazole moieties as carbonic anhydrase I, II, IV and IX inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 183, pp. 1-10, ISSN:0223-5234 DOI  

  Abo-Ashour M.F.; Eldehna W.M.; Nocentini A.; Bonardi A.; Bua S.; Ibrahim H.S.; Elaasser M.M.; Krystof V.; Jorda R.; Gratteri P.; Abou-Seri S.M.; Supuran C.T. (2019). 3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 184, pp. 1-11, ISSN:0223-5234 DOI  

  Yamali C.; Gul H.I.; Ece A.; Bua S.; Angeli A.; Sakagami H.; Sahin E.; Supuran C.T. (2019). Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors. BIOORGANIC CHEMISTRY, vol. 92, pp. 103222-103222, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Narella S.G.; Shaik M.G.; Mohammed A.; Alvala M.; Angeli A.; Supuran C.T. (2019). Synthesis and biological evaluation of coumarin-1,3,4-oxadiazole hybrids as selective carbonic anhydrase IX and XII inhibitors. BIOORGANIC CHEMISTRY, vol. 87, pp. 765-772, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Tanini, Damiano; Capperucci, Antonella; Ferraroni, Marta; Carta, Fabrizio; Angeli, Andrea; Supuran, Claudiu T. (2019). Direct and Straightforward access to substituted alkyl selenols as novel carbonic anhydrase inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, pp. 111811-111817, ISSN:0223-5234 DOI  

  Gustavo Provensi, Fabrizio Carta, Alessio Nocentini, Claudiu T. Supuran, Fiorella Casamenti, Maria Beatrice Passani, Silvia Fossati (2019). A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer's Disease. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, pp. 4724-4741, ISSN:1422-0067 DOI  

  Moi D.; Nocentini A.; Deplano A.; Balboni G.; Supuran C.T.; Onnis V. (2019). Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 182, pp. 111638-111649, ISSN:1768-3254 DOI  

  Zengin Kurt B.; Sonmez F.; Ozturk D.; Akdemir A.; Angeli A.; Supuran C.T. (2019). Synthesis of coumarin-sulfonamide derivatives and determination of their cytotoxicity, carbonic anhydrase inhibitory and molecular docking studies. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 183, pp. 111702-111702, ISSN:1768-3254 DOI   Accesso ONLINE all'editore

  Mustafa G.; Angeli A.; Zia-ur-Rehman M.; Akbar N.; Ishtiaq S.; Supuran C.T. (2019). An efficient method for the synthesis of novel derivatives 4-5-[4-(4-amino-5-mercapto-4H-[1,2,4]triazol-3-yl)-phenyl]-3-trifluoromethyl-pyrazol-1-yl-benzenesulfonamide and their anti-inflammatory potential. BIOORGANIC CHEMISTRY, vol. 91, pp. 103110-103110, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Distinto S.; Meleddu R.; Ortuso F.; Cottiglia F.; Deplano S.; Sequeira L.; Melis C.; Fois B.; Angeli A.; Capasso C.; Angius R.; Alcaro S.; Supuran C.T.; Maccioni E. (2019). Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34, pp. 1526-1533, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Del Prete S.; Angeli A.; Ghobril C.; Hitce J.; Clavaud C.; Marat X.; Supuran C.T.; Capasso C. (2019). Anion inhibition profile of the β-carbonic anhydrase from the opportunist pathogenic fungus malassezia restricta involved in dandruff and seborrheic dermatitis. METABOLITES, vol. 9, pp. 147-147, ISSN:2218-1989 DOI   Accesso ONLINE all'editore

  Tugrak M.; Gul H.I.; Bandow K.; Sakagami H.; Gulcin I.; Ozkay Y.; Supuran C.T. (2019). Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors. BIOORGANIC CHEMISTRY, vol. 90, pp. 103095-103104, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Swain B.; Singh Digwal C.; Angeli A.; Alvala M.; Singh P.; Supuran C.T.; Arifuddin M. (2019). Synthesis and exploration of 2-morpholino-4-phenylthiazol-5-yl acrylamide derivatives for their effects against carbonic anhydrase I, II, IX and XII isoforms as a non-sulfonamide class of inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 27, pp. 115090-115090, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Angeli A.; Supuran C.T. (2019). Prostaglandin receptor agonists as antiglaucoma agents (a patent review 2013–2018). EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 29, pp. 793-803, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  Angeli A.; Del Prete S.; Osman S.M.; AlOthman Z.; Donald W.A.; Capasso C.; Supuran C.T. (2019). Activation studies of the γ-carbonic anhydrases from the antarctic marine bacteria pseudoalteromonas haloplanktis and colwellia psychrerythraea with amino acids and amines. MARINE DRUGS, vol. 17, pp. 238-247, ISSN:1660-3397 DOI  

  Angeli A.; Ferraroni M.; Nocentini A.; Selleri S.; Gratteri P.; Supuran C.T.; Carta F. (2019). Polypharmacology of epacadostat: A potent and selective inhibitor of the tumor associated carbonic anhydrases IX and XII. CHEMICAL COMMUNICATIONS, vol. 55, pp. 5720-5723, ISSN:1359-7345 DOI   Accesso ONLINE all'editore

  Mboge M.Y.; Chen Z.; Khokhar D.; Wolff A.; Ai L.; Heldermon C.D.; Bozdag M.; Carta F.; Supuran C.T.; Brown K.D.; McKenna R.; Frost C.J.; Frost S.C. (2019). A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells. BIOCHEMICAL JOURNAL, vol. 476, pp. 1497-1513, ISSN:0264-6021 DOI   Accesso ONLINE all'editore

  Costa G.; Carta F.; Ambrosio F.A.; Artese A.; Ortuso F.; Moraca F.; Rocca R.; Romeo I.; Lupia A.; Maruca A.; Bagetta D.; Catalano R.; Vullo D.; Alcaro S.; Supuran C.T. (2019). A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 181, pp. 111565-111572, ISSN:1768-3254 DOI  

  Laura Micheli, Murat Bozdag , Ozlem Akgul , Fabrizio Carta , Clizia Guccione, Maria Camilla Bergonzi, Anna Rita Bilia, Lorenzo Cinci, Elena Lucarini, Carmen Parisio, Claudiu T. Supuran , Carla Ghelardini, Lorenzo Di Cesare Mannelli (2019). Pain Relieving Eect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, pp. 0-0, ISSN:1422-0067

  Abdel-Aziz, Alaa A.-M.; El-Azab, Adel S.; Ghiaty, Adel H.; Gratteri, Paola; Supuran, Claudiu T.; Nocentini, Alessio (2019). 4-Substituted benzenesulfonamides featuring cyclic imides moieties exhibit potent and isoform-selective carbonic anhydrase II/IX inhibition. BIOORGANIC CHEMISTRY, vol. 83, pp. 198-204, ISSN:0045-2068, Academic Press Inc.: 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA DOI   Accesso ONLINE all'editore

  Nocentini, Alessio; Lucidi, Alessia; Perut, Francesca; Massa, Annamaria; Tomaselli, Daniela; Gratteri, Paola; Baldini, Nicola; Rotili, Dante; Mai, Antonello; Supuran, Claudiu T.* (2019). α,γ-Diketocarboxylic Acids and Their Esters Act as Carbonic Anhydrase IX and XII Selective Inhibitors. ACS MEDICINAL CHEMISTRY LETTERS, vol. 10, pp. 661-665, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Allam H.A.; Fahim S.H.; F.Abo-Ashour M.; Nocentini A.; Elbakry M.E.; Abdelrahman M.A.; Eldehna W.M.; Ibrahim H.S.; Supuran C.T. (2019). Application of hydrazino and hydrazido linkers to connect benzenesulfonamides with hydrophilic/phobic tails for targeting the middle region of human carbonic anhydrases active site: Selective inhibitors of hCA IX. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 179, pp. 547-556, ISSN:1768-3254 DOI   Accesso ONLINE all'editore

  Angeli A.; Pinteala M.; Maier S.S.; Del Prete S.; Capasso C.; Simionescu B.C.; Supuran C.T. (2019). Inhibition of α-, β-, γ-, δ-, ζ- and η-class carbonic anhydrases from bacteria, fungi, algae, diatoms and protozoans with famotidine. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34, pp. 644-650, ISSN:1475-6366 DOI  

  Thacker P.S.; Shaikh P.; Angeli A.; Arifuddin M.; Supuran C.T. (2019). Synthesis and biological evaluation of novel 8-substituted quinoline-2-carboxamides as carbonic anhydrase inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34, pp. 1172-1177, ISSN:1475-6366 DOI  

  Angeli A.; Del Prete S.; Pinteala M.; Maier S.S.; Donald W.A.; Simionescu B.C.; Capasso C.; Supuran C.T. (2019). The first activation study of the β-carbonic anhydrases from the pathogenic bacteria Brucella suis and Francisella tularensis with amines and amino acids. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34, pp. 1178-1185, ISSN:1475-6366 DOI  

  Kurt B.Z.; Dag A.; Dogan B.; Durdagi S.; Angeli A.; Nocentini A.; Supuran C.T.; Sonmez F. (2019). Synthesis, biological activity and multiscale molecular modeling studies of bis-coumarins as selective carbonic anhydrase IX and XII inhibitors with effective cytotoxicity against hepatocellular carcinoma. BIOORGANIC CHEMISTRY, vol. 87, pp. 838-850, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Buemi M.R.; Di Fiore A.; De Luca L.; Angeli A.; Mancuso F.; Ferro S.; Monti S.M.; Buonanno M.; Russo E.; De Sarro G.; De Simone G.; Supuran C.T.; Gitto R. (2019). Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 163, pp. 443-452, ISSN:1768-3254 DOI   Accesso ONLINE all'editore

  Da'dara A.A.; Angeli A.; Ferraroni M.; Supuran C.T.; Skelly P.J. (2019). Crystal structure and chemical inhibition of essential schistosome host-interactive virulence factor carbonic anhydrase SmCA. COMMUNICATIONS BIOLOGY, vol. 2, pp. 333-333, ISSN:2399-3642 DOI   Accesso ONLINE all'editore

  Somers K.; Wen V.W.; Middlemiss S.M.C.; Osborne B.; Forgham H.; Jung M.S.; Karsa M.; Clifton M.; Bongers A.; Gao J.; Mayoh C.; Raoufi-Rad N.; Kusnadi E.P.; Hannan K.M.; Scott D.A.; Kwek A.; Liu B.; Flemming C.; Chudakova D.A.; Pandher R.; Failes T.W.; Lim J.; Angeli A.; Osterman A.L.; Imamura T.; Kees U.R.; Supuran C.T.; Pearson R.B.; Hannan R.D.; Davis T.P.; McCarroll J.; Kavallaris M.; Turner N.; Gudkov A.V.; Haber M.; Norris M.D.; Henderson M.J. (2019). A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. ONCOGENE, vol. 38, pp. 3824-3842, ISSN:0950-9232 DOI   Accesso ONLINE all'editore

  Rotondi G.; Guglielmi P.; Carradori S.; Secci D.; De Monte C.; De Filippis B.; Maccallini C.; Amoroso R.; Cirilli R.; Akdemir A.; Angeli A.; Supuran C.T. (2019). Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34, pp. 1400-1413, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Abdel-Aziz A.A.-M.; Angeli A.; El-Azab A.S.; Hammouda M.E.A.; El-Sherbeny M.A.; Supuran C.T. (2019). Synthesis and anti-inflammatory activity of sulfonamides and carboxylates incorporating trimellitimides: Dual cyclooxygenase/carbonic anhydrase inhibitory actions. BIOORGANIC CHEMISTRY, vol. 84, pp. 260-268, ISSN:0045-2068 DOI  

  Angeli A.; Pinteala M.; Maier S.S.; Del Prete S.; Capasso C.; Simionescu B.C.; Supuran C.T. (2019). Inhibition of bacterial α-, β- and γ-class carbonic anhydrases with selenazoles incorporating benzenesulfonamide moieties. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34, pp. 244-249, ISSN:1475-6366 DOI  

  Akdemir A.; Angeli A.; Goktas F.; Eraslan Elma P.; Karali N.; Supuran C.T. (2019). Novel 2-indolinones containing a sulfonamide moiety as selective inhibitors of candida β-carbonic anhydrase enzyme. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34, pp. 528-531, ISSN:1475-6366 DOI  

  Ammazzalorso A.; Carradori S.; Angeli A.; Akdemir A.; De Filippis B.; Fantacuzzi M.; Giampietro L.; Maccallini C.; Amoroso R.; Supuran C.T. (2019). Fibrate-based N-acylsulphonamides targeting carbonic anhydrases: synthesis, biochemical evaluation, and docking studies. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34, pp. 1051-1061, ISSN:1475-6366 DOI  

  Payaz D.U.; Kucukbay F.Z.; Kucukbay H.; Angeli A.; Supuran C.T. (2019). Synthesis carbonic anhydrase enzyme inhibition and antioxidant activity of novel benzothiazole derivatives incorporating glycine, methionine, alanine, and phenylalanine moieties. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34, pp. 343-349, ISSN:1475-6366 DOI  

  Aspatwar A.; Kairys V.; Rala S.; Parikka M.; Bozdag M.; Carta F.; Supuran C.T.; Parkkila S. (2019). Mycobacterium tuberculosisβ-Carbonic Anhydrases: Novel Targets for Developing Antituberculosis Drugs. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, pp. 5153-5169, ISSN:1422-0067 DOI  

  Vats, Lalit; Sharma, Vikas; Angeli, Andrea; Kumar, Rajiv; Supuran, Claudiu T.; Sharma, Pawan K.* (2018). Synthesis of novel 4-functionalized 1,5-diaryl-1,2,3-triazoles containing benzenesulfonamide moiety as carbonic anhydrase I, II, IV and IX inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 150, pp. 678-686, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Awadallah, Fadi M.; Bua, Silvia; Mahmoud, Walaa R.; Nada, Hossam H.; Nocentini, Alessio; Supuran, Claudiu T.* (2018). Inhibition studies on a panel of human carbonic anhydrases with N1-substituted secondary sulfonamides incorporating thiazolinone or imidazolone-indole tails. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 629-638, ISSN:1475-6366 DOI  

  Ferraroni, Marta; Cornelio, Benedetta; Sapi, Janos; Supuran, Claudiu T.; Scozzafava, Andrea (2018). Sulfonamide carbonic anhydrase inhibitors: Zinc coordination and tail effects influence inhibitory efficacy and selectivity for different isoforms. INORGANICA CHIMICA ACTA, vol. 470, pp. 128-132, ISSN:0020-1693 DOI   Accesso ONLINE all'editore

  Havránková, Eva; Csöllei, Jozef; Vullo, Daniela; Garaj, Vladimír; Pazdera, Pavel; Supuran, Claudiu T (2018). Novel sulfonamide incorporating piperazine, aminoalcohol and 1,3,5-triazine structural motifs with carbonic anhydrase I, II and IX inhibitory action. BIOORGANIC CHEMISTRY, vol. 77, pp. 25-37, ISSN:0045-2068 DOI  

  Vullo, Daniela; Lehneck, Ronny; Pöggeler, Stefanie; Supuran, Claudiu T (2018). Sulfonamide inhibition studies of two β-carbonic anhydrases from the ascomycete fungus Sordaria macrospora, CAS1 and CAS2. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 390-396, ISSN:1475-6366 DOI  

  Angapelly, Srinivas; Angeli, Andrea; Jabbar Khan, Arbaj; SriRamya, Posa Venkata; Supuran, Claudiu Trandafir; Arifuddin, Mohammed (2018). Synthesis and Biological Evaluation of 4-sulfamoylphenyl/sulfocoumarin carboxamides as selective inhibitors of carbonic anhydrase isoforms hCA II, IX and XII. CHEMMEDCHEM, pp. 1-9, ISSN:1860-7179 DOI  

  Ibrahim, Hany S.*; Allam, Heba Abdelrasheed; Mahmoud, Walaa R.; Bonardi, Alessandro; Nocentini, Alessio; Gratteri, Paola; Ibrahim, Eslam S.; Abdel-Aziz, Hatem A.; Supuran, Claudiu T. (2018). Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 152, pp. 1-9, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Mujumdar, Prashant; Bua, Silvia; Supuran, Claudiu T.; Peat, Thomas S.; Poulsen, Sally-Ann* (2018). Synthesis, structure and bioactivity of primary sulfamate-containing natural products. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, pp. 1-5, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Harter, Till Sebastian; May, Alexandra G; Federspiel, William J; Supuran, Claudiu T; Brauner, Colin J (2018). The time-course of red blood cell intracellular pH recovery following short-circuiting in relation to venous transit times in rainbow trout, Oncorhynchus mykiss. AMERICAN JOURNAL OF PHYSIOLOGY. REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, pp. 1-44, ISSN:0363-6119 DOI  

  Supuran, Claudiu T.; Alterio, Vincenzo; Di Fiore, Anna; D' Ambrosio, Katia; Carta, Fabrizio; Monti, Simona Maria; De Simone, Giuseppina* (2018). Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one. MEDICINAL RESEARCH REVIEWS, pp. 1-38, ISSN:0198-6325 DOI   Accesso ONLINE all'editore

  Aspatwar A.; Winum J.-Y.; Carta F.; Supuran C.T.; Hammaren M.; Parikka M.; Parkkila S. (2018). Carbonic anhydrase inhibitors as novel drugs against mycobacterial β-carbonic anhydrases: An update on in vitro and in vivo studies. MOLECULES, vol. 23, pp. 2911-2925, ISSN:1420-3049 DOI   Accesso ONLINE all'editore

  Mboge M.Y.; Chen Z.; Wolff A.; Mathias J.V.; Tu C.; Brown K.D.; Bozdag M.; Carta F.; Supuran C.T.; McKenna R.; Frost S.C. (2018). Selective inhibition of carbonic anhydrase IX over carbonic anhydrase XII in breast cancer cells using benzene sulfonamides: Disconnect between activity and growth inhibition. PLOS ONE, vol. 13, pp. e0207417--, ISSN:1932-6203 DOI  

  Mahmood, Shams-ul; Saeed, Aamer*; Bua, Sivia; Nocentini, Alessio; Gratteri, Paola; Supuran, Claudiu T. (2018). Synthesis, biological evaluation and computational studies of novel iminothiazolidinone benzenesulfonamides as potent carbonic anhydrase II and IX inhibitors. BIOORGANIC CHEMISTRY, vol. 77, pp. 381-386, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Angeli A.; Kuuslahti M.; Parkkila S.; Supuran C.T. (2018). Activation studies with amines and amino acids of the α-carbonic anhydrase from the pathogenic protozoan Trypanosoma cruzi. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 26, pp. 4187-4190, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Zolnowska B.; Slawinski J.; Szafranski K.; Angeli A.; Supuran C.T.; Kawiak A.; Wieczor M.; Zielinska J.; Baczek T.; Bartoszewska S. (2018). Novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(1,3,5-triazin-2-ylamino)guanidine derivatives: Inhibition of human carbonic anhydrase cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII, anticancer activity, and molecular modeling studies. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 143, pp. 1931-1941, ISSN:1768-3254 DOI   Accesso ONLINE all'editore

  De Simone G.; Angeli A.; Bozdag M.; Supuran C.T.; Winum J.-Y.; Monti S.M.; Alterio V. (2018). Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate binding. CHEMICAL COMMUNICATIONS, vol. 54, pp. 10312-10315, ISSN:1359-7345 DOI   Accesso ONLINE all'editore

  Mishra C.B.; Kumari S.; Angeli A.; Bua S.; Buonanno M.; Monti S.M.; Tiwari M.; Supuran C.T. (2018). Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in vitro and in vivo appraisal. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 156, pp. 430-443, ISSN:0223-5234 DOI  

  Guzel-Akdemir O.; Angeli A.; Demir K.; Supuran C.T.; Akdemir A. (2018). Novel thiazolidinone-containing compounds, without the well-known sulphonamide zinc-binding group acting as human carbonic anhydrase IX inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 1299-1308, ISSN:1475-6366 DOI  

  Angeli, Andrea; Alasmary, Fatmah A. S.; Del Prete, Sonia; Osman, Sameh M.; AlOthman, Zeid; Donald, William A.; Capasso, Clemente; Supuran, Claudiu T. (2018). The first activation study of a δ-carbonic anhydrase: TweCAδ from the diatom Thalassiosira weissflogii is effectively activated by amines and amino acids. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 680-685, ISSN:1475-6366 DOI  

  Bonardi, Alessandro; Falsini, Matteo; Catarzi, Daniela; Varano, Flavia; Di Cesare Mannelli, Lorenzo; Tenci, Barbara; Ghelardini, Carla; Angeli, Andrea; Supuran, Claudiu T.; Colotta, Vittoria* (2018). Structural investigations on coumarins leading to chromeno[4,3-c]pyrazol-4-ones and pyrano[4,3-c]pyrazol-4-ones: New scaffolds for the design of the tumor-associated carbonic anhydrase isoforms IX and XII. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 146, pp. 47-59, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Monti, Simona Maria; Meccariello, Angela; Ceruso, Mariangela; Szafrański, Krzysztof; Sławiński, Jarosław; Supuran, Claudiu T (2018). Inhibition studies of Brucella suis β-carbonic anhydrases with a series of 4-substituted pyridine-3-sulphonamides. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 255-259, ISSN:1475-6366 DOI  

  Murray, Akilah B; Lomelino, Carrie L; Supuran, Claudiu T; Mckenna, Robert (2018). "Seriously Sweet": Acesulfame K Exhibits Selective Inhibition Using Alternative Binding Modes in Carbonic Anhydrase Isoforms. JOURNAL OF MEDICINAL CHEMISTRY, pp. 1-6, ISSN:0022-2623 DOI  

  Angeli, Andrea; Del Prete, Sonia; Osman, Sameh M; Alasmary, Fatmah A S; Alothman, Zeid; Donald, William A; Capasso, Clemente; Supuran, Claudiu T (2018). Activation studies of the α- and β-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae with amines and amino acids. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 227-233, ISSN:1475-6366 DOI  

  Angeli, Andrea; Tanini, Damiano; Capperucci, Antonella; Supuran, Claudiu T. (2018). First evaluation of organotellurium derivatives as carbonic anhydrase I, II, IV, VII and IX inhibitors. BIOORGANIC CHEMISTRY, vol. 76, pp. 268-272, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Alterio, Vincenzo; Esposito, Davide; Monti, Simona Maria; Supuran, Claudiu T.; De Simone, Giuseppina (2018). Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 151-157, ISSN:1475-6366 DOI  

  De Luca, Laura; Mancuso, Francesca; Ferro, Stefania; Buemi, Maria Rosa; Angeli, Andrea; Del Prete, Sonia; Capasso, Clemente; Supuran, Claudiu T.; Gitto, Rosaria (2018). Inhibitory effects and structural insights for a novel series of coumarin-based compounds that selectively target human CA IX and CA XII carbonic anhydrases. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 143, pp. 276-282, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Nocentini, Alessio; Cadoni, Roberta; Dumy, Pascal; Supuran, Claudiu T; Winum, Jean-Yves (2018). Carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani chagasi are inhibited by benzoxaboroles. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 286-289, ISSN:1475-6366 DOI  

  Angeli, Andrea; Chiaramonte, Niccolò; Manetti, Dina; Romanelli, Maria Novella; Supuran, Claudiu T (2018). Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 303-308, ISSN:1475-6366 DOI  

  Angeli, Andrea; Del Prete, Sonia; Donald, William A.; Capasso, Clemente; Supuran, Claudiu T. (2018). The γ-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae is potently activated by amines and amino acids. BIOORGANIC CHEMISTRY, vol. 77, pp. 1-5, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Del Prete, Sonia; Osman, Sameh M; Alasmary, Fatmah A S; Alothman, Zeid; Donald, William A; Capasso, Clemente; Supuran, Claudiu T (2018). Activation studies with amines and amino acids of the β-carbonic anhydrase encoded by the Rv3273 gene from the pathogenic bacterium Mycobacterium tuberculosis. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 364-369, ISSN:1475-6366 DOI  

  Vullo, Daniela; Syrjänen, Leo; Kuuslahti, Marianne; Parkkila, Seppo; Supuran, Claudiu T (2018). Anion inhibition studies of a beta carbonic anhydrase from the malaria mosquito Anopheles gambiae. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 359-363, ISSN:1475-6366 DOI  

  Peperidou, Aikaterini; Bua, Silvia; Bozdag, Murat; Hadjipavlou-Litina, Dimitra; Supuran, Claudiu T (2018). Novel 6- and 7-Substituted Coumarins with Inhibitory Action against Lipoxygenase and Tumor-Associated Carbonic Anhydrase IX. MOLECULES, vol. 23, pp. 1-17, ISSN:1420-3049 DOI  

  Aday, Burak; Ulus, Ramazan; Tanã§, Muhammet; Kaya, Muharrem; Supuran, Claudiu T. (2018). Synthesis of novel 5-amino-1,3,4-thiadiazole-2-sulfonamide containing acridine sulfonamide/carboxamide compounds and investigation of their inhibition effects on human carbonic anhydrase I, II, IV and VII. BIOORGANIC CHEMISTRY, vol. 77, pp. 101-105, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Arias-Hidalgo, Mariela; Yuan, Qinggong; Carta, Fabrizio; Supuran, Claudiu T.; Gros, Gerolf; Endeward, Volker (2018). CO2Permeability of Rat Hepatocytes and Relation of CO2Permeability to CO2Production. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, vol. 46, pp. 1198-1208, ISSN:1015-8987 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Donald, William A.; Parkkila, Seppo; Supuran, Claudiu T. (2018). Activation studies with amines and amino acids of the β-carbonic anhydrase from the pathogenic protozoan Leishmania donovani chagasi. BIOORGANIC CHEMISTRY, vol. 78, pp. 406-410, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Métayer, Benoit; Angeli, Andrea; Mingot, Agnès; Jouvin, Kévin; Evano, Gwilherm; Supuran, Claudiu T.; Thibaudeau, Sébastien* (2018). Fluoroenesulphonamides: N-sulphonylurea isosteres showing nanomolar selective cancer-related transmembrane human carbonic anhydrase inhibition. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 804-808, ISSN:1475-6366 DOI  

  da Silva Cardoso, Verônica; Vermelho, Alane Beatriz; Ricci Junior, Eduardo; Almeida Rodrigues, Igor; Mazotto, Ana Maria; Supuran, Claudiu T.* (2018). Antileishmanial activity of sulphonamide nanoemulsions targeting the β-carbonic anhydrase from Leishmania species. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 850-857, ISSN:1475-6366 DOI  

  Shabana, Ahmed M; Mondal, Utpal K; Alam, Md Raqibul; Spoon, Taylor; Ross, Codee Alicia; Madesh, Muniswamy; Supuran, Claudiu T; Ilies, Marc A (2018). pH-Sensitive Multi-ligand Gold Nanoplatform Targeting Carbonic Anhydrase IX Enhances the Delivery of Doxorubicin to Hypoxic Tumor Spheroids and Overcomes the Hypoxia-Induced Chemoresistance. ACS APPLIED MATERIALS & INTERFACES, pp. 1-52, ISSN:1944-8244 DOI  

  Menicatti, Marta; Pallecchi, Marco; Bua, Silvia; Vullo, Daniela; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Carta, Fabrizio; Supuran, Claudiu T.; Bartolucci, Gianluca* (2018). Resolution of co-eluting isomers of anti-inflammatory drugs conjugated to carbonic anhydrase inhibitors from plasma in liquid chromatography by energy-resolved tandem mass spectrometry. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 671-679, ISSN:1475-6366 DOI  

  Langella, Emma; Buonanno, Martina; Vullo, Daniela; Dathan, Nina; Leone, Marilisa; Supuran, Claudiu T.; de Simone, Giuseppina*; Monti, Simona Maria (2018). Biochemical, biophysical and molecular dynamics studies on the proteoglycan-like domain of carbonic anhydrase IX. CELLULAR AND MOLECULAR LIFE SCIENCES, pp. 1-14, ISSN:1420-682X DOI   Accesso ONLINE all'editore

  Akgul, Ozlem; Di Cesare Mannelli, Lorenzo; Vullo, Daniela; Angeli, Andrea; Ghelardini, Carla; Bartolucci, Gianluca; Altamimi, Abdulmalik Saleh Alfawaz; Scozzafava, Andrea; Supuran, Claudiu T; Carta, Fabrizio (2018). Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Management of Rheumatoid Arthritis. JOURNAL OF MEDICINAL CHEMISTRY, pp. 1-60, ISSN:0022-2623 DOI  

  Nocentini, Alessio; Carta, Fabrizio; Tanc, Muhammet; Selleri, Silvia; Supuran, Claudiu T.; Bazzicalupi, Carla*; Gratteri, Paola (2018). Deciphering the Mechanism of Human Carbonic Anhydrases Inhibition with Sulfocoumarins: Computational and Experimental Studies. CHEMISTRY-A EUROPEAN JOURNAL, vol. 24, pp. 7840-7844, ISSN:0947-6539 DOI   Accesso ONLINE all'editore

  Angapelly, Srinivas; Ramya, P. V. Sri; Sodhi, Rohini; Angeli, Andrea; Rangan, Krishnan; Nagesh, Narayana; Supuran, Claudiu T.; Arifuddin, Mohammed* (2018). Iodine-mediated one-pot intramolecular decarboxylation domino reaction for accessing functionalised 2-(1,3,4-oxadiazol-2-yl)anilines with carbonic anhydrase inhibitory action. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 615-628, ISSN:1475-6366 DOI  

  Bua, Silvia; Bozdag, Murat; Del Prete, Sonia; Carta, Fabrizio; Donald, William A; Capasso, Clemente; Supuran, Claudiu T (2018). Mono- and di-thiocarbamate inhibition studies of the δ-carbonic anhydrase TweCAδ from the marine diatom Thalassiosira weissflogii. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 707-713, ISSN:1475-6366 DOI  

  Niccolò Chiaramonte, Silvia Bua, Marta Ferraroni, Alessio Nocentini, Alessandro Bonardi, Gian Luca Bartolucci, Maria Concetta Durante, Laura Lucarini, Donata Chiapponi, Silvia Dei, Dina Manetti, Elisabetta Teodori, Paola Gratteri, Emanuela Masini, Claudiu T. Supuran, Maria Novella Romanelli (2018). 2-Benzylpiperazine: a new scaffold for potent human Carbonic Anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 151, pp. 363-375, ISSN:1768-3254 DOI  

  Nocentini, Alessio; Bua, Silvia; Del Prete, Sonia; Heravi, Yeganeh Entezari; Saboury, Ali A; Karioti, Anastasia; Bilia, Anna Rita; Capasso, Clemente; Gratteri, Paola; Supuran, Claudiu T (2018). Natural Polyphenols Selectively Inhibit β-Carbonic Anhydrase from the Dandruff-Producing Fungus Malassezia globosa: Activity and Modeling Studies. CHEMMEDCHEM, vol. 13, pp. 816-823, ISSN:1860-7179 DOI  

  Bua, Silvia; Berrino, Emanuela; Del Prete, Sonia; Murthy, Vallabhaneni S; Vijayakumar, Vijayaparthasarathi; Tamboli, Yasinalli; Capasso, Clemente; Cerbai, Elisabetta; Mugelli, Alessandro; Carta, Fabrizio; Supuran, Claudiu T (2018). Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae α- and β-class enzymes. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 1125-1136, ISSN:1475-6366 DOI  

  Provensi, G ; Schmidt, SD; Rani, B ; Costa, A ; Carta, F ; de Carvalho Myskiw, J.; Passani, MB ; Izquierdo, I ; Supuran, CT; Blandina P (2018). BRAIN CARBONIC ANHYDRASES INHIBITION IMPAIRS FEAR MEMORY EXTINCTION IN RATS. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, vol. 123, pp. 61-61, ISSN:1742-7835

  Logsdon, Derek P.; Shah, Fenil; Carta, Fabrizio; Supuran, Claudiu T.; Kamocka, Malgorzata; Jacobsen, Max H.; Sandusky, George E.; Kelley, Mark R.; Fishel, Melissa L. (2018). Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival. SCIENTIFIC REPORTS, vol. 8, pp. 13759-13773, ISSN:2045-2322 DOI   Accesso ONLINE all'editore

  Angeli A, di Cesare Mannelli L, Lucarini E, Peat TS, Ghelardini C, Supuran CT (2018). Design, synthesis and X-ray crystallography of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, pp. 210-219, ISSN:0223-5234 DOI  

  Chiaramonte, Niccolò*; Romanelli, Maria Novella; Teodori, Elisabetta; Supuran, Claudiu T. (2018). Amino acids as building blocks for carbonic anhydrase inhibitors. METABOLITES, vol. 8, pp. 1-22, ISSN:2218-1989 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Trallori, Elena; Carta, Fabrizio; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Supuran, Claudiu T.* (2018). Heterocoumarins Are Selective Carbonic Anhydrase IX and XII Inhibitors with Cytotoxic Effects against Cancer Cells Lines. ACS MEDICINAL CHEMISTRY LETTERS, vol. 9, pp. 947-951, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Di Cesare Mannelli, Lorenzo; Trallori, Elena; Peat, Thomas S.; Ghelardini, Carla; Carta, Fabrizio; Supuran, Claudiu T.* (2018). Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology. ACS MEDICINAL CHEMISTRY LETTERS, vol. 9, pp. 462-467, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Tanini, Damiano; Capperucci, Antonella; Malevolti, Gianni; Turco, Francesca; Ferraroni, Marta; Supuran, Claudiu T.* (2018). Synthesis of different thio-scaffolds bearing sulfonamide with subnanomolar carbonic anhydrase II and IX inhibitory properties and X-ray investigations for their inhibitory mechanism. BIOORGANIC CHEMISTRY, vol. 81, pp. 642-648, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Ferraroni, Marta; Supuran, Claudiu T.* (2018). Famotidine, an Antiulcer Agent, Strongly Inhibits Helicobacter pylori and Human Carbonic Anhydrases. ACS MEDICINAL CHEMISTRY LETTERS, vol. 9, pp. 1035-1038, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Trallori, Elena; Ferraroni, Marta; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Supuran, Claudiu T.* (2018). Discovery of new 2, 5-disubstituted 1,3-selenazoles as selective human carbonic anhydrase IX inhibitors with potent anti-tumor activity. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 157, pp. 1214-1222, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Ferraroni, Marta*; Gaspari, Roberto; Scozzafava, Andrea; Cavalli, Andrea; Supuran, Claudiu T. (2018). Dioxygen, an unexpected carbonic anhydrase ligand. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 999-1005, ISSN:1475-6366 DOI  

  Silvia Bua; Marta Menicatti; Paola Gratteri; Alessio Nocentini; Claudiu T. Supuran; Gian Luca Bartolucci (2018). STABILITY STUDY IN PLASMA OF NOVEL ESTER-LINKED NSAID - CARBONIC ANHYDRASE INHIBITOR HYBRIDS. In: XXII International Mass Spectrometry Conference, Florence (Italy), August 26-31, 2018, 22nd IMSC SCIENTIFIC COMMITTEE, pp. 841-842, ISBN:9788890738852

  Donato Squillaci; Marta Menicatti; Silvia Bua; Claudiu T. Supuran; Gian Luca Bartolucci (2018). APPLICATION OF LINEAR EQUATIONS DECONVOLUTION ANALYSIS (LEDA) ALGORITHM IN ION TRAP MASS SPECTROMETRY: RESOLUTION OF ISOMERIC PAIRS OF CARBONIC ANHYDRASE AND CYCLOOXYGENASE HYBRIDS INHIBITORS. In: XXII International Mass Spectrometry Conference, Florence (Italy), August 26-31, 2018, 22nd IMSC SCIENTIFIC COMMITTEE, pp. 846-847, ISBN:9788890738852

  Buğday, Nesrin; Küçükbay, F. Zehra; Küçükbay, Hasan*; Bua, Silvia; Bartolucci, Gian Luca; Leitans, Janis; Kazaks, Andris; Tars, Kaspars; Supuran, Claudiu T. (2018). Synthesis of novel dipeptide sulfonamide conjugates with effective carbonic anhydrase I, II, IX, and XII inhibitory properties. BIOORGANIC CHEMISTRY, vol. 81, pp. 311-318, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  E. Teodori, M. Coronnello, S. Bua, L. Braconi, D. Manetti, M.N. Romanelli, C. Supuran, S. Dei (2018). P-glycoprotein and carbonic anhydrases hybrid inhibitors: a new strategy to reverse multidrug resistance (MDR) in cancer cells. In: Italian-Spanish-Portoguese Joint Meeting in Medicinal Chemistry MedChemSicily 2018, Palermo, 17-20 luglio, Società Chimica Italiana, pp. P 31-P 31.

  Zhang Y.; Supuran C.T.; Barboiu M. (2018). Exponential Activation of Carbonic Anhydrase by Encapsulation in Dynameric Host Matrices with Chiral Discrimination. CHEMISTRY-A EUROPEAN JOURNAL, vol. 24, pp. 715-720, ISSN:0947-6539 DOI   Accesso ONLINE all'editore

  Nocentini A, Trallori E, Singh S, Lomelino CL, Bartolucci G, Di Cesare Mannelli L, Ghelardini C, McKenna R, Gratteri P, Supuran CT (2018). 4-Hydroxy-3-nitro-5-ureido-benzenesulfonamides selectively target the tumor-associated carbonic anhydrase isoforms IX and XII showing hypoxia-enhanced anti-proliferative profiles.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 61, pp. 10860-10874, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Nocentini, Alessio; Bonardi, Alessandro; Gratteri, Paola; Cerra, Bruno; Gioiello, Antimo*; Supuran, Claudiu T. (2018). Steroids interfere with human carbonic anhydrase activity by using alternative binding mechanisms. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 1453-1459, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Gul H.I.; Yamali C.; Sakagami H.; Angeli A.; Leitans J.; Kazaks A.; Tars K.; Ozgun D.O.; Supuran C.T. (2018). New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors. BIOORGANIC CHEMISTRY, vol. 77, pp. 411-419, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Meleddu R.; Distinto S.; Cottiglia F.; Angius R.; Gaspari M.; Taverna D.; Melis C.; Angeli A.; Bianco G.; Deplano S.; Fois B.; Del Prete S.; Capasso C.; Alcaro S.; Ortuso F.; Yanez M.; Supuran C.T.; Maccioni E. (2018). Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides. ACS MEDICINAL CHEMISTRY LETTERS, vol. 9, pp. 1045-1050, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Melis C.; Distinto S.; Bianco G.; Meleddu R.; Cottiglia F.; Fois B.; Taverna D.; Angius R.; Alcaro S.; Ortuso F.; Gaspari M.; Angeli A.; Del Prete S.; Capasso C.; Supuran C.T.; Maccioni E. (2018). Targeting Tumor Associated Carbonic Anhydrases IX and XII: Highly Isozyme Selective Coumarin and Psoralen Inhibitors. ACS MEDICINAL CHEMISTRY LETTERS, vol. 9, pp. 725-729, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Angeli A.; Buonanno M.; Donald W.A.; Monti S.M.; Supuran C.T. (2018). The zinc – but not cadmium – containing ζ-carbonic from the diatom Thalassiosira weissflogii is potently activated by amines and amino acids. BIOORGANIC CHEMISTRY, vol. 80, pp. 261-265, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Angeli A.; Abbas G.; del Prete S.; Capasso C.; Supuran C.T. (2018). Selenides bearing benzenesulfonamide show potent inhibition activity against carbonic anhydrases from pathogenic bacteria Vibrio cholerae and Burkholderia pseudomallei. BIOORGANIC CHEMISTRY, vol. 79, pp. 319-322, ISSN:0045-2068 DOI  

  Angeli A.; Del Prete S.; Alasmary F.A.S.; Alqahtani L.S.; AlOthman Z.; Donald W.A.; Capasso C.; Supuran C.T. (2018). The first activation studies of the η-carbonic anhydrase from the malaria parasite Plasmodium falciparum with amines and amino acids. BIOORGANIC CHEMISTRY, vol. 80, pp. 94-98, ISSN:0045-2068 DOI  

  Nocentini, Alessio; Ceruso, Mariangela; Bua, Silvia; Lomelino, Carrie L.; Andring, Jacob T.; McKenna, Robert; Lanzi, Cecilia; Sgambellone, Silvia; Pecori, Riccardo; Matucci, Rosanna; Filippi, Luca; Gratteri, Paola; Carta, Fabrizio; Masini, Emanuela; Selleri, Silvia*; Supuran, Claudiu T. (2018). Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy. JOURNAL OF MEDICINAL CHEMISTRY, vol. 61, pp. 5380-5394, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Mocan A.; Carradori S.; Locatelli M.; Secci D.; Cesa S.; Mollica A.; Riga S.; Angeli A.; Supuran C.T.; Celia C.; Di Marzio L. (2018). Bioactive isoflavones from Pueraria lobata root and starch: Different extraction techniques and carbonic anhydrase inhibition. FOOD AND CHEMICAL TOXICOLOGY, vol. 112, pp. 441-447, ISSN:0278-6915 DOI   Accesso ONLINE all'editore

  Angeli A.; Supuran C.T. (2018). Treatment of sleep apnea with a combination of a carbonic anhydrase inhibitor and an aldosterone antagonist: a patent evaluation of CA2958110 and IN6616DEN2012. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 28, pp. 723-727, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  Stefanucci A.; Angeli A.; Dimmito M.P.; Luisi G.; Del Prete S.; Capasso C.; Donald W.A.; Mollica A.; Supuran C.T. (2018). Activation of β- and γ-carbonic anhydrases from pathogenic bacteria with tripeptides. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 945-950, ISSN:1475-6366 DOI  

  Mikus P.; Krajciova D.; Mikulova M.; Horvath B.; Pecher D.; Garaj V.; Bua S.; Angeli A.; Supuran C.T. (2018). Novel sulfonamides incorporating 1,3,5-triazine and amino acid structural motifs as inhibitors of the physiological carbonic anhydrase isozymes I, II and IV and tumor-associated isozyme IX. BIOORGANIC CHEMISTRY, vol. 81, pp. 241-252, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Annunziato G.; Giovati L.; Angeli A.; Pavone M.; Del Prete S.; Pieroni M.; Capasso C.; Bruno A.; Conti S.; Magliani W.; Supuran C.T.; Costantino G. (2018). Discovering a new class of antifungal agents that selectively inhibits microbial carbonic anhydrases. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 1537-1544, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Bozdag M.; Carta F.; Angeli A.; Osman S.M.; Alasmary F.A.S.; AlOthman Z.; Supuran C.T. (2018). Synthesis of N′-phenyl-N-hydroxyureas and investigation of their inhibitory activities on human carbonic anhydrases. BIOORGANIC CHEMISTRY, vol. 78, pp. 1-6, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Abdoli M.; Bozdag M.; Angeli A.; Supuran C.T. (2018). Benzamide-4-sulfonamides are effective human carbonic anhydrase I, II, VII, and IX inhibitors. METABOLITES, vol. 8, pp. 37-48, ISSN:2218-1989 DOI  

  Bozdag, Murat; Carta, Fabrizio; Ceruso, Mariangela; Ferraroni, Marta; McDonald, Paul C.; Dedhar, Shoukat; Supuran, Claudiu T.* (2018). Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides as SLC-0111 Analogues for the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX. JOURNAL OF MEDICINAL CHEMISTRY, vol. 61, pp. 6328-6338, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Supuran, Claudiu T (2018). Carbonic Anhydrases and Metabolism. METABOLITES, vol. 8, pp. 25-29, ISSN:2218-1989 DOI  

  Gul, Halise Inci*; Yamali, Cem; Bulbuller, Merve; Kirmizibayrak, Petek Ballar; Gul, Mustafa; Angeli, Andrea; Bua, Silvia; Supuran, Claudiu T. (2018). Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes. BIOORGANIC CHEMISTRY, vol. 78, pp. 290-297, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Mishra, Chandra Bhushan; Kumari, Shikha; Angeli, Andrea; Bua, Silvia; Tiwari, Manisha*; Supuran, Claudiu T. (2018). Discovery of benzenesulfonamide derivatives as carbonic anhydrase inhibitors with effective anticonvulsant action: Design, synthesis, and pharmacological evaluation. JOURNAL OF MEDICINAL CHEMISTRY, vol. 61, pp. 3151-3165, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Bragagni M.; Carta F.; Osman S.M.; AlOthman Z.; Supuran C.T. (2017). Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 701-706, ISSN:1475-6366 DOI  

  Aspatwar A.; Hammaren M.; Koskinen S.; Luukinen B.; Barker H.; Carta F.; Supuran C.T.; Parikka M.; Parkkila S. (2017). β-CA-specific inhibitor dithiocarbamate Fc14–584B: a novel antimycobacterial agent with potential to treat drug-resistant tuberculosis. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 832-840, ISSN:1475-6366 DOI  

  Kusuzaki K.; Matsubara T.; Murata H.; Logozzi M.; Iessi E.; Di Raimo R.; Carta F.; Supuran C.T.; Fais S. (2017). Natural extracellular nanovesicles and photodynamic molecules: is there a future for drug delivery?. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 908-916, ISSN:1475-6366 DOI  

  Ivanova J.; Carta F.; Vullo D.; Leitans J.; Kazaks A.; Tars K.; Zalubovskis R.; Supuran C.T. (2017). N-Substituted and ring opened saccharin derivatives selectively inhibit transmembrane, tumor-associated carbonic anhydrases IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 3583-3589, ISSN:0968-0896 DOI  

  Meehan J.; Ward C.; Turnbull A.; Bukowski-Wills J.; Finch A.J.; Jarman E.J.; Xintaropoulou C.; Martinez-Perez C.; Gray M.; Pearson M.; Mullen P.; Supuran C.T.; Carta F.; Harrison D.J.; Kunkler I.H.; Langdon S.P. (2017). Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells. ONCOTARGET, vol. 8, pp. 42857-42875, ISSN:1949-2553 DOI  

  Ivanova, Jekaterīna; Balode, Agnese; Žalubovskis, Raivis; Leitans, Janis; Kazaks, Andris; Vullo, Daniela; Tars, Kaspars; Supuran, Claudiu T. (2017). 5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 857-863, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Kumar, Rajiv; Bua, Silvia; Ram, Sita; Del Prete, Sonia; Capasso, Clemente; Supuran, Claudiu T; Sharma, Pawan K. (2017). Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 1286-1293, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Alper Türkoğlu, Emir; Şentürk, Murat; Supuran, Claudiu T; Ekinci, Deniz (2017). Carbonic anhydrase inhibitory properties of some uracil derivatives. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 74-77, ISSN:1475-6366 DOI  

  Altug, Cevher; Güneş, Hanife; Nocentini, Alessio; Monti, Simona Maria; Buonanno, Martina; Supuran, Claudiu T. (2017). Synthesis of isoxazole-containing sulfonamides with potent carbonic anhydrase II and VII inhibitory properties. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 1456-1464, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Bhatt, Avni; Mahon, Brian P.; Cruzeiro, Vinicius Wilian D.; Cornelio, Benedetta; Laronze-Cochard, Marie; Ceruso, Mariangela; Sapi, Janos; Rance, Graham A.; Khlobystov, Andrei N.; Fontana, Antonella; Roitberg, Adrian; Supuran, Claudiu T.; Mckenna, Robert (2017). Structure–Activity Relationships of Benzenesulfonamide-Based Inhibitors towards Carbonic Anhydrase Isoform Specificity. CHEMBIOCHEM, vol. 18, pp. 213-222, ISSN:1439-4227 DOI   Accesso ONLINE all'editore

  Esirden, İbrahim; Tanç, Muhammet; Supuran, Claudiu T; Kaya, Muharrem (2017). Microwave assisted synthesis of novel tetrazole/sulfonamide derivatives based on octahydroacridine, xanthene and chromene skeletons as inhibitors of the carbonic anhydrases isoforms I, II, IV and VII. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 27, pp. 86-89, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Nescatelli, Riccardo; Carradori, Simone; Marini, Federico; Caponigro, Vicky; Bucci, Remo; De Monte, Celeste; Mollica, Adriano; Mannina, Luisa; Ceruso, Mariangela; Supuran, Claudiu T.; Secci, Daniela (2017). Geographical characterization by MAE-HPLC and NIR methodologies and carbonic anhydrase inhibition of Saffron components. FOOD CHEMISTRY, vol. 221, pp. 855-863, ISSN:0308-8146 DOI   Accesso ONLINE all'editore

  Gul, Halise Inci; Mete, Ebru; Taslimi, Parham; Gulcin, Ilhami; Supuran, Claudiu T (2017). Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 189-192, ISSN:1475-6366 DOI  

  Melis, Claudia; Meleddu, Rita; Angeli, Andrea; Distinto, Simona; Bianco, Giulia; Capasso, Clemente; Cottiglia, Filippo; Angius, Rossella; Supuran, CLAUDIU TRANDAFIR; Maccioni, Elias (2017). Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 68-73, ISSN:1475-6366 DOI  

  Sapegin, Alexander; Kalinin, Stanislav; Angeli, Andrea; Supuran, Claudiu T.; Krasavin, Mikhail (2017). Unprotected primary sulfonamide group facilitates ring-forming cascade en route to polycyclic [1,4]oxazepine-based carbonic anhydrase inhibitors. BIOORGANIC CHEMISTRY, vol. 76, pp. 140-146, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Kalinin, Stanislav; Kopylov, Stanislav; Tuccinardi, Tiziano; Sapegin, Alexander; Dar'In, Dmitry; Angeli, Andrea; Supuran, Claudiu T.; Krasavin, Mikhail (2017). Lucky Switcheroo: Dramatic Potency and Selectivity Improvement of Imidazoline Inhibitors of Human Carbonic Anhydrase VII. ACS MEDICINAL CHEMISTRY LETTERS, vol. 8, pp. 1105-1109, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Wang, Huixin; Yong, Grace; Brown, Susannah L.; Lee, Hyun Eui; Zenaidee, Muhammad A.; Supuran, Claudiu T.; Donald, William A. (2017). Supercharging protein ions in native mass spectrometry using theta capillary nanoelectrospray ionization mass spectrometry and cyclic alkylcarbonates. ANALYTICA CHIMICA ACTA, vol. 1003, pp. 1-9, ISSN:0003-2670 DOI   Accesso ONLINE all'editore

  Bozdag, Murat; Alafeefy, Ahmed Mahmoud; Altamimi, Abdul Malik; Carta, Fabrizio; Supuran, Claudiu T.*; Vullo, Daniela (2017). Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 2782-2788, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Ferraroni, Marta; Lucarini, Laura; Masini, Emanuela; Korsakov, Mikhail; Scozzafava, Andrea; Supuran, Claudiu T.*; Krasavin, Mikhail (2017). 1,3-Oxazole-based selective picomolar inhibitors of cytosolic human carbonic anhydrase II alleviate ocular hypertension in rabbits: Potency is supported by X-ray crystallography of two leads. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 4560-4565, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Carta, Fabrizio; Vullo, Daniela; Osman, Sameh M.; AlOthman, Zeid; Supuran, Claudiu T. (2017). Synthesis and carbonic anhydrase inhibition of a series of SLC-0111 analogs. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 2569-2576, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Supuran, Claudiu T (2017). Advances in structure-based drug discovery of carbonic anhydrase inhibitors. EXPERT OPINION ON DRUG DISCOVERY, vol. 12, pp. 61-88, ISSN:1746-0441 DOI  

  Bruno E.; Buemi M.R.; Di Fiore A.; De Luca L.; Ferro S.; Angeli A.; Cirilli R.; Sadutto D.; Alterio V.; Monti S.M.; Supuran C.T.; De Simone G.; Gitto R. (2017). Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides. JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, pp. 4316-4326, ISSN:0022-2623 DOI  

  Angapelly S.; Ramya P.V.S.; Angeli A.; Monti S.M.; Buonanno M.; Alvala M.; Supuran C.T.; Arifuddin M. (2017). Discovery of 4-sulfamoyl-phenyl-β-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 539-544, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Mboge M.Y.; Mahon B.P.; Lamas N.; Socorro L.; Carta F.; Supuran C.T.; Frost S.C.; McKenna R. (2017). Structure activity study of carbonic anhydrase IX: Selective inhibition with ureido-substituted benzenesulfonamides. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 132, pp. 184-191, ISSN:0223-5234 DOI  

  Del Prete, Sonia; Vullo, Daniela; di Fonzo, Pietro; Carginale, Vincenzo; Supuran, Claudiu T; Capasso, Clemente (2017). Comparison of the anion inhibition profiles of the β- and γ-carbonic anhydrases from the pathogenic bacterium Burkholderia pseudomallei. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 2010-2015, ISSN:0968-0896 DOI  

  Krasavin, Mikhail; Korsakov, Mikhail; Zvonaryova, Zhanna; Semyonychev, Evgenii; Tuccinardi, Tiziano; Kalinin, Stanislav; Tanç, Muhammet; Supuran, Claudiu T (2017). Human carbonic anhydrase inhibitory profile of mono- and bis-sulfonamides synthesized via a direct sulfochlorination of 3- and 4-(hetero)arylisoxazol-5-amine scaffolds. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 1914-1925, ISSN:0968-0896 DOI  

  Capasso, Clemente; Supuran, Claudiu (2017). Inhibition of Bacterial Carbonic Anhydrases as a Novel Approach to Escape Drug Resistance. CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol. 17, pp. 1237-1248, ISSN:1568-0266 DOI  

  Le Duc, Yann; Licsandru, Erol; Vullo, Daniela; Barboiu, Mihail; Supuran, Claudiu T. (2017). Carbonic anhydrases activation with 3-amino-1H-1,2,4-triazole-1-carboxamides: Discovery of subnanomolar isoform II activators. BIOORGANIC & MEDICINAL CHEMISTRY, pp. 31458-31464, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Abdel-Aziz, Aa; Angeli, A; El-Azab, As; Abu El-Enin, Ma; Supuran, Ct (2017). Synthesis and biological evaluation of cyclic imides incorporating benzenesulfonamide moieties as carbonic anhydrase I, II, IV and IX inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY, pp. 31418-31423, ISSN:0968-0896 DOI  

  Vermelho, Ab; Capaci, Gr; Rodrigues, Ia; Cardoso, Vs; Mazotto, Am; Supuran, Ct. (2017). Carbonic anhydrases from Trypanosoma and Leishmania as anti-protozoan drug targets. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 1543-1555, ISSN:0968-0896 DOI  

  Perfetto, Rosa; Del Prete, Sonia; Vullo, Daniela; Sansone, Giovanni; Barone, Carmela; Rossi, Mosè; Supuran, Claudiu T; Capasso, Clemente (2017). Biochemical characterization of the native α-carbonic anhydrase purified from the mantle of the Mediterranean mussel, Mytilus galloprovincialis. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 632-639, ISSN:1475-6366 DOI  

  Fares, Mohamed; Eladwy, Radwa A.; Nocentini, Alessio; El Hadi, Soha R. Abd; Ghabbour, Hazem A.; Abdel-Megeed, Ashraf; Eldehna, Wagdy M.; Abdel-Aziz, Hatem A.; Supuran, Claudiu T. (2017). Synthesis of bulky-tailed sulfonamides incorporating pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-1(5H)-yl) moieties and evaluation of their carbonic anhydrases I, II, IV and IX inhibitory effects. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 2210-2217, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Mishra, Chandra Bhushan; Kumari, Shikha; Angeli, Andrea; Monti, Simona Maria; Buonanno, Martina; Tiwari, Manisha; Supuran, Claudiu T (2017). Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment. JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, pp. 2456-2469, ISSN:0022-2623 DOI  

  Gul, Halise Inci; Yamali, Cem; Yesilyurt, Fatma; Sakagami, Hiroshi; Kucukoglu, Kaan; Gulcin, Ilhami; Gul, Mustafa; Supuran, Claudiu T (2017). Microwave-assisted synthesis and bioevaluation of new sulfonamides. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 369-374, ISSN:1475-6366 DOI  

  Vullo, Daniela; Del Prete, Sonia; Di Fonzo, Pietro; Carginale, Vincenzo; Donald, W Alexander; Supuran, Claudiu T; Capasso, Clemente (2017). Comparison of the Sulfonamide Inhibition Profiles of the β- and γ-Carbonic Anhydrases from the Pathogenic Bacterium Burkholderia pseudomallei. MOLECULES, vol. 22, pp. 421-435, ISSN:1420-3049 DOI  

  Del Prete, Sonia; Vullo, Daniela; Di Fonzo, Pietro; Osman, Sameh M.; Alothman, Zeid; Donald, William A.; Supuran, Claudiu T.; Capasso, Clemente (2017). Sulfonamide inhibition profile of the γ-carbonic anhydrase identified in the genome of the pathogenic bacterium Burkholderia pseudomallei the etiological agent responsible of melioidosis. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 27, pp. 490-495, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Soydan, Ercan; Güler, Ahmet; Bıyık, Selim; Şentürk, Murat; Supuran, Claudiu T; Ekinci, Deniz (2017). Carbonic anhydrase from Apis mellifera: purification and inhibition by pesticides. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 47-50-50, ISSN:1475-6366 DOI  

  Fisher, Gillian M.; Bua, Silvia; Del Prete, Sonia; Arnold, Megan S.J.; Capasso, Clemente; Supuran, Claudiu T.; Andrews, Katherine T.; Poulsen, Sally-Ann (2017). Investigating the antiplasmodial activity of primary sulfonamide compounds identified in open source malaria data. INTERNATIONAL JOURNAL FOR PARASITOLOGY, DRUGS AND DRUG RESISTANCE, vol. 7, pp. 61-70, ISSN:2211-3207 DOI   Accesso ONLINE all'editore

  Del Prete, Sonia; Vullo, Daniela; Di Fonzo, Pietro; Osman, Sameh M.; Alothman, Zeid; Supuran, Claudiu T.; Capasso, Clemente (2017). Anion inhibition profiles of the γ-carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei responsible of melioidosis and highly drug resistant to common antibiotics. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 575-580, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Bozdag, Murat; Alafeefy, Ahmed Mahmoud; Altamimi, Abdul Malik; Vullo, Daniela; Carta, Fabrizio; Supuran, Claudiu T. (2017). Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 677-683, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Monti, Daria M.; De Simone, Giuseppina; Langella, Emma; Supuran, Claudiu T.; Di Fiore, Anna; Monti, Simona Maria (2017). Insights into the role of reactive sulfhydryl groups of carbonic anhydrase III and VII during oxidative damage. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 5-12, ISSN:1475-6366 DOI  

  Bua, Silvia; Di Cesare Mannelli, Lorenzo; Vullo, Daniela; Ghelardini, Carla; Bartolucci, Gianluca; Scozzafava, Andrea; Supuran, Claudiu T; Carta, Fabrizio (2017). Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis. JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, pp. 1159-1170, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Tanini, Damiano; Viglianisi, Caterina; Panzella, Lucia; Capperucci, Antonella; Menichetti, Stefano; Supuran, Claudiu T (2017). Evaluation of selenide, diselenide and selenoheterocycle derivatives as carbonic anhydrase I, II, IV, VII and IX inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 2518-2523, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Entezari Heravi, Yeganeh; Bua, Silvia; Nocentini, Alessio; Del Prete, Sonia; Saboury, Ali Akbar; Sereshti, Hassan; Capasso, Clemente; Gratteri, Paola; Supuran, Claudiu T (2017). Inhibition of Malassezia globosa carbonic anhydrase with phenols. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 2577-2582, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Vaiano, Fabio; Mari, Francesco; Bertol, Elisabetta; Supuran, Claudiu T (2017). Psychoactive substances belonging to the amphetamine class potently activate brain carbonic anhydrase isoforms VA, VB, VII, and XII. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 1253-1259-1259, ISSN:1475-6366 DOI  

  Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Di Cesare Mannelli, Lorenzo; Tenci, Barbara; Ghelardini, Carla; Tanc, Muhammet; Angeli, Andrea; Supuran, Claudiu T.; Colotta, Vittoria (2017). 3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold to Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII. JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, pp. 6428-6439, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Berrino, Emanuela; Bua, Silvia; Mori, Mattia; Botta, Maurizio; Murthy, Vallabhaneni S.; Vijayakumar, Vijayaparthasarathi; Tamboli, Yasinalli; Bartolucci, Gianluca; Mugelli, Alessandro; Cerbai, Elisabetta; Supuran, Claudiu T.; Carta, Fabrizio (2017). Novel sulfamide-containing compounds as selective carbonic anhydrase i inhibitors. MOLECULES, vol. 22, pp. 1049-1065, ISSN:1420-3049 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Tanini, Damiano; Peat, Thomas S. ; Di Cesare Mannelli,Lorenzo; Bartolucci, Gian Luca; Capperucci, Antonella; Ghelardini, Carla; Supuran, Claudiu T.; and Carta, Fabrizio (2017). Discovery of New Selenoureido Analogues of 4-(4-Fluorophenylureido)benzenesulfonamide as Carbonic Anhydrase Inhibitors. ACS MEDICINAL CHEMISTRY LETTERS, vol. 8, pp. 963-968, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Vermelho, Alane Beatriz; da Silva Cardoso, Verônica; Ricci Junior, Eduardo; Dos Santos, Elisabete Pereira; Supuran, Claudiu T. (2017). Nanoemulsions of sulfonamide carbonic anhydrase inhibitors strongly inhibit the growth of Trypanosoma cruzi. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 139-146, ISSN:1475-6366 DOI  

  Ramya, P. V. Sri; Angapelly, Srinivas; Angeli, Andrea; Digwal, Chander Singh; Arifuddin, Mohammed; Babu, Bathini Nagendra; Supuran, Claudiu T; Kamal, Ahmed (2017). Discovery of curcumin inspired sulfonamide derivatives as a new class of carbonic anhydrase isoforms I, II, IX, and XII inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 1274-1281, ISSN:1475-6366 DOI  

  Eldehna, Wagdy M.; Abo-Ashour, Mahmoud F.; Nocentini, Alessio; Gratteri, Paola; Eissa, Ibrahim H.; Fares, Mohamed; Ismael, Omnia E.; Ghabbour, Hazem A.; Elaasser, Mahmoud M.; Abdel-Aziz, Hatem A.; Supuran, Claudiu T. (2017). Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 139, pp. 250-262, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Nocentini, Alessio; Bua, Silvia; Lomelino, Carrie L.; Mckenna, Robert; Menicatti, Marta; Bartolucci, Gianluca; Tenci, Barbara; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Gratteri, Paola; Supuran, Claudiu T. (2017). Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases. ACS MEDICINAL CHEMISTRY LETTERS, vol. 8, pp. 1314-1319, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Abdel-Aziz, Alaa A. -. M.; Nocentini, Alessio; El-Azab, Adel S.; Gratteri, Paola; Supuran, Claudiu T. (2017). Synthesis and carbonic anhydrase inhibition of polycyclic imides incorporating N-benzenesulfonamide moieties. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 5373-5379, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Nocentini, Alessio; Vullo, Daniela; Del Prete, Sonia; Osman, Sameh M.; Alasmary, Fatmah A. S.; Alothman, Zeid; Capasso, Clemente; Carta, Fabrizio; Gratteri, Paola; Supuran, Claudiu T. (2017). Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 1064-1070, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Cadoni, Roberta; Pala, Nicolino; Lomelino, Carrie; Mahon, Brian P.; Mckenna, Robert; Dallocchio, Roberto; Dessã¬, Alessandro; Carcelli, Mauro; Rogolino, Dominga; Sanna, Vanna; Rassu, Mauro; Iaccarino, Ciro; Vullo, Daniela; Supuran, Claudiu T.; Sechi, Mario (2017). Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors. ACS MEDICINAL CHEMISTRY LETTERS, vol. 8, pp. 941-946, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Luisi, Grazia; Angelini, Guido; Gasbarri, Carla; Laghezza, Antonio; Agamennone, Mariangela; Loiodice, Fulvio; Supuran, Claudiu T; Campestre, Cristina; Tortorella, Paolo (2017). Dual targeting of cancer-related human matrix metalloproteinases and carbonic anhydrases by chiral N-(biarylsulfonyl)-phosphonic acids. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 1260-1264, ISSN:1475-6366 DOI  

  Krasavin, Mikhail; Shetnev, Anton; Sharonova, Tatyana; Baykov, Sergey; Tuccinardi, Tiziano; Kalinin, Stanislav; Angeli, Andrea; Supuran, Claudiu T. (2017). Heterocyclic periphery in the design of carbonic anhydrase inhibitors: 1,2,4-Oxadiazol-5-yl benzenesulfonamides as potent and selective inhibitors of cytosolic hCA II and membrane-bound hCA IX isoforms. BIOORGANIC CHEMISTRY, vol. 76, pp. 88-97, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Akocak, Suleyman; Lolak, Nabih; Vullo, Daniela; Durgun, Mustafa; Supuran, Claudiu T. (2017). Synthesis and biological evaluation of histamine Schiff bases as carbonic anhydrase I, II, IV, VII, and IX activators. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 1305-1312, ISSN:1475-6366 DOI  

  Supuran, Claudiu T. (2017). Special Issue: Sulfonamides. MOLECULES, vol. 22, pp. 1-5, ISSN:1420-3049 DOI  

  Nocentini, Alessio; Cadoni, Roberta; Del Prete, Sonia; Capasso, Clemente; Dumy, Pascal; Gratteri, Paola; Supuran, Claudiu T.; Winum, Jean-Yves (2017). Benzoxaboroles as Efficient Inhibitors of the β-Carbonic Anhydrases from Pathogenic Fungi: Activity and Modeling Study. ACS MEDICINAL CHEMISTRY LETTERS, vol. 8, pp. 1194-1198, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Riafrecha, Leonardo E.; Bua, Silvia; Supuran, Claudiu T.; Colinas, Pedro A. (2017). Improving the carbonic anhydrase inhibition profile of the sulfamoylphenyl pharmacophore by attachment of carbohydrate moieties. BIOORGANIC CHEMISTRY, vol. 76, pp. 61-66, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Vullo, Daniela; Del Prete, Sonia; Osman, Sameh M; Alasmary, Fatmah A. S; Alothman, Zeid; Donald, William A; Capasso, Clemente; Supuran, Claudiu T. (2017). Comparison of the amine/amino acid activation profiles of the β- and γ-carbonic anhydrases from the pathogenic bacterium Burkholderia pseudomallei. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 25-30, ISSN:1475-6366 DOI  

  Angapelly, Srinivas; Sri Ramya, P. V.; Angeli, Andrea; Supuran, Claudiu T.; Arifuddin, Mohammed (2017). Sulfocoumarin-, Coumarin-, 4-Sulfamoylphenyl-Bearing Indazole-3-carboxamide Hybrids: Synthesis and Selective Inhibition of Tumor-Associated Carbonic Anhydrase Isozymes IX and XII. CHEMMEDCHEM, vol. 12, pp. 1578-1584, ISSN:1860-7179 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Abbas, Ghulam; Del Prete, Sonia; Carta, Fabrizio; Capasso, Clemente; Supuran, Claudiu T. (2017). Acyl selenoureido benzensulfonamides show potent inhibitory activity against carbonic anhydrases from the pathogenic bacterium Vibrio cholerae. BIOORGANIC CHEMISTRY, vol. 75, pp. 170-172, ISSN:0045-2068 DOI   Accesso ONLINE all'editore

  Supuran, Claudiu T; Capasso, Clemente (2017). An Overview of the Bacterial Carbonic Anhydrases. METABOLITES, vol. 7, pp. 1-19, ISSN:2218-1989 DOI  

  Fragai, Marco; Comito, Giuseppina; Di Cesare Mannelli, Lorenzo; Gualdani, Roberta; Calderone, Vito; Louka, Alexandra; Richichi, Barbara; Francesconi, Oscar; Angeli, Andrea; Nocentini, Alessio; Gratteri, Paola; Chiarugi, Paola; Ghelardini, Carla; Tadini-Buoninsegni, Francesco; Supuran, Claudiu T; Nativi, Cristina (2017). Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX). JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, pp. 9003-9011, ISSN:1520-4804 DOI  

  Vullo, Daniela; Kumar, R. Siva Sai; Scozzafava, Andrea; Ferry, James G; Supuran, Claudiu T. (2017). Sulphonamide inhibition studies of the β-carbonic anhydrase from the bacterial pathogen Clostridium perfringens. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 31-36, ISSN:1475-6366 DOI  

  Andreucci, Elena; Peppicelli, Silvia; Carta, Fabrizio; Brisotto, Giulia; Biscontin, Eva; Ruzzolini, Jessica; Bianchini, Francesca; Biagioni, Alessio; Supuran, Claudiu T.; Calorini, Lido (2017). Carbonic anhydrase IX inhibition affects viability of cancer cells adapted to extracellular acidosis. JOURNAL OF MOLECULAR MEDICINE, vol. 95, pp. 1341-1353, ISSN:0946-2716 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Tanini, Damiano; Capperucci, Antonella; Supuran, Claudiu T. (2017). Synthesis of Novel Selenides Bearing Benzenesulfonamide Moieties as Carbonic Anhydrase I, II, IV, VII, and IX Inhibitors. ACS MEDICINAL CHEMISTRY LETTERS, vol. 8, pp. 1213-1217, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Mollica, Adriano; Macedonio, Giorgia; Stefanucci, Azzurra; Carradori, Simone; Akdemir, Atilla; Angeli, Andrea; Supuran, Claudiu T (2017). Five- and Six-Membered Nitrogen-Containing Compounds as Selective Carbonic Anhydrase Activators. MOLECULES, vol. 22, pp. 1-13, ISSN:1420-3049 DOI  

  Patrikainen, Maarit S.; Tolvanen, Martti E. E.; Aspatwar, Ashok; Barker, Harlan R.; Ortutay, Csaba; Jã¤nis, Janne; Laitaoja, Mikko; Hytã¶nen, Vesa P.; Azizi, Latifeh; Manandhar, Prajwol; Jã¡ger, Edit; Vullo, Daniela; Kukkurainen, Sampo; Hilvo, Mika; Supuran, Claudiu T.; Parkkila, Seppo (2017). Identification and characterization of a novel zebrafish (Danio rerio) pentraxin-carbonic anhydrase. PEERJ, vol. 2017, pp. 1-38, ISSN:2167-8359 DOI   Accesso ONLINE all'editore

  Del Prete, Sonia; Vullo, Daniela; Caminiti-Segonds, Natacha; Zoccola, Didier; Tambutté, Sylvie; Supuran, Claudiu T; Capasso, Clemente (2017). Protonography and anion inhibition profile of the α-carbonic anhydrase (CruCA4) identified in the Mediterranean red coral Corallium rubrum. BIOORGANIC CHEMISTRY, vol. 76, pp. 281-287, ISSN:0045-2068 DOI  

  Cau, Ylenia; Vullo, Daniela; Mori, Mattia; Dreassi, Elena; Supuran, Claudiu T; Botta, Maurizio (2017). Potent and Selective Carboxylic Acid Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII. MOLECULES, vol. 23, pp. 1-14, ISSN:1420-3049 DOI  

  Del Prete, Sonia; Vullo, Daniela; Zoccola, Didier; Tambutté, Sylvie; Supuran, Claudiu T; Capasso, Clemente (2017). Activation Profile Analysis of CruCA4, an α-Carbonic Anhydrase Involved in Skeleton Formation of the Mediterranean Red Coral, Corallium rubrum. MOLECULES, vol. 23, pp. 1-10, ISSN:1420-3049 DOI  

  Iessi, Elisabetta; Logozzi, Mariantonia; Mizzoni, Davide; Di Raimo, Rossella; Supuran, Claudiu T; Fais, Stefano (2017). Rethinking the Combination of Proton Exchanger Inhibitors in Cancer Therapy. METABOLITES, vol. 8, pp. 1-20, ISSN:2218-1989 DOI  

  Vullo, Daniela; Del Prete, Sonia; Nocentini, Alessio; Osman, Sameh M.; Alothman, Zeid; Capasso, Clemente; Bozdag, Murat; Carta, Fabrizio; Gratteri, Paola; Supuran, Claudiu T. (2017). Dithiocarbamates effectively inhibit the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 1260-1265, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Bertol, Elisabetta; Vaiano, Fabio; Mari, Francesco; Di Milia, Maria Grazia; Bua, Silvia; Supuran, Claudiu Trandafir; Carta, Fabrizio (2017). Advances in New Psychoactive Substances Identification: The U.R.I.To.N Consortium. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 841-849, ISSN:1475-6366 DOI  

  Lucarini, Laura; Magnelli, Lucia; Schiavone, Nicola; Crisci, Alfonso; Innocenti, Alessio; Puccetti, Luca; Cianchi, Fabio; Peri, Sara; Supuran, CLAUDIU TRANDAFIR; Papucci, Laura; Masini, Emanuela; (2017). PLASMATIC CARBONIC ANHYDRASE IX AS A DIAGNOSTIC MARKER FOR CLEAR CELL RENAL CELL CARCINOMA. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, pp. 234-240, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Carta, Fabrizio*; Birkmann, Alexander; Pfaff, Tamara; Buschmann, Helmut; Schwab, Wilfried; Zimmermann, Holger; Maresca, Alfonso; Supuran, Claudiu T. (2017). Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action. JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, pp. 3154-3164, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Angeli, Andrea; Carta, Fabrizio; Bartolucci, Gian Luca; Supuran, Claudiu T.* (2017). Synthesis of novel acyl selenoureido benzensulfonamides as carbonic anhydrase I, II, VII and IX inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 3567-3573, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Eldehna, Wagdy M; Al-Ansary, Ghada H.; Bua, Silvia; Nocentini, Alessio; Gratteri, Paola; Altoukhy, Ayman; Ghabbour, Hazem; Ahmed, Hanaa Y.; Supuran, Claudiu T. (2017). Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and molecular docking studies. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 127, pp. 521-530, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Abdoli M.; Angeli A.; Bozdag M.; Carta F.; Kakanejadifard A.; Saeidian H.; Supuran C.T. (2017). Synthesis and carbonic anhydrase I, II, VII, and IX inhibition studies with a series of benzo[d]thiazole-5- and 6-sulfonamides. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 1071-1078, ISSN:1475-6366 DOI  

  Bianco G, Meleddu R, Distinto S, Cottiglia F, Gaspari M, Melis C, Corona A, Angius R, Angeli A, Taverna D, Alcaro S, Leitans J, Kazaks A, Tars K, Supuran CT, Maccioni E. (2017). N-Acylbenzenesulfonamide Dihydro-1,3,4-oxadiazole Hybrids: Seeking Selectivity toward Carbonic Anhydrase Isoforms. ACS MEDICINAL CHEMISTRY LETTERS, pp. 792-796, ISSN:1948-5875 DOI  

  Karali N.; Akdemir A.; Goktas F.; Eraslan Elma P.; Angeli A.; Kizilirmak M.; Supuran C.T. (2017). Novel sulfonamide-containing 2-indolinones that selectively inhibit tumor-associated alpha carbonic anhydrases. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 3714-3718, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Lucas Canto de Souza, Gustavo Provensi, Daniela Vullo, Fabrizio Carta, Andrea Scozzafava, Alessia Costa, Scheila D. Schmidt; Maria Beatrice Passani, Claudiu T. Supuran, Patrizio Blandina (2017). Carbonic anhydrase activation enhances object recognition memory in mice through phosphorylation of the extracellular signal-regulated kinase in the cortex and the hippocampus.. NEUROPHARMACOLOGY, vol. 118, pp. 148-156, ISSN:1873-7064 DOI   Accesso ONLINE all'editore

  Angapelly S.; Ramya P.V.S.; Angeli A.; Del Prete S.; Capasso C.; Arifuddin M.; Supuran C.T. (2017). Development of sulfonamides incorporating phenylacrylamido functionalities as carbonic anhydrase isoforms I, II, IX and XII inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 5726-5732, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Zengin Kurt B.; Sonmez F.; Durdagi S.; Aksoydan B.; Ekhteiari Salmas R.; Angeli A.; Kucukislamoglu M.; Supuran C.T. (2017). Synthesis, biological activity and multiscale molecular modeling studies for coumaryl-carboxamide derivatives as selective carbonic anhydrase IX inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 1042-1052, ISSN:1475-6366 DOI  

  De Vita D.; Angeli A.; Pandolfi F.; Bortolami M.; Costi R.; Di Santo R.; Suffredini E.; Ceruso M.; Del Prete S.; Capasso C.; Scipione L.; Supuran C.T. (2017). Inhibition of the α-carbonic anhydrase from Vibrio cholerae with amides and sulfonamides incorporating imidazole moieties. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 798-804, ISSN:1475-6366 DOI  

  Gul, Halise Inci; Tugrak, Mehtap; Sakagami, Hiroshi; Taslimi, Parham; Gulcin, Ilhami; Supuran, Claudiu T. (2016). Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1619-1624, ISSN:1475-6366 DOI  

  Turan, Burhanettin; Şendil, Kivilcim; Şengül, Emin; Gültekin, Mehmet Serdar; Taslimi, Parham; Gulçin, İlhami; Supuran, Claudiu T. (2016). The synthesis of some β-lactams and investigation of their metal-chelating activity, carbonic anhydrase and acetylcholinesterase inhibition profiles. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 79-88, ISSN:1475-6366 DOI  

  Hanff, Erik; Böhmer, Anke; Zinke, Maximilian; Gambaryan, Stepan; Schwarz, Alexandra; Supuran, Claudiu T.; Tsikas, Dimitrios (2016). Carbonic anhydrases are producers of S-nitrosothiols from inorganic nitrite and modulators of soluble guanylyl cyclase in human platelets. AMINO ACIDS, vol. 48, pp. 1695-1706, ISSN:0939-4451 DOI   Accesso ONLINE all'editore

  Di Fiore, Anna; De Simone, Giuseppina; Alterio, Vincenzo; Riccio, Vincenzo; Winum, Jean-Yves; Carta, Fabrizio; Supuran, Claudiu T. (2016). The anticonvulsant sulfamide JNJ-26990990 and its: S, S -dioxide analog strongly inhibit carbonic anhydrases: Solution and X-ray crystallographic studies. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 14, pp. 4853-4858, ISSN:1477-0520 DOI   Accesso ONLINE all'editore

  Supuran, Claudiu T; Kalinin, Stanislav; Tanç, Muhammet; Sarnpitak, Pakornwit; Mujumdar, Prashant; Poulsen, Sally-Ann; Krasavin, Mikhail (2016). Isoform-selective inhibitory profile of 2-imidazoline-substituted benzene sulfonamides against a panel of human carbonic anhydrases. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 197-202, ISSN:1475-6366 DOI  

  Kumar, Satish; Ceruso, Mariangela; Tuccinardi, Tiziano; Supuran, Claudiu T; Sharma, Pawan K. (2016). Pyrazolylbenzo[d]imidazoles as new potent and selective inhibitors of carbonic anhydrase isoforms hCA IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 2907-2913, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Mishra, Chandra Bhushan; Kumari, Shikha; Angeli, Andrea; Monti, Simona Maria; Buonanno, Martina; Prakash, Amresh; Tiwari, Manisha; Supuran, Claudiu T. (2016). Design, synthesis and biological evaluation of N-(5-methyl-isoxazol-3-yl/1,3,4-thiadiazol-2-yl)-4-(3-substitutedphenylureido) benzenesulfonamides as human carbonic anhydrase isoenzymes I, II, VII and XII inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 174-179, ISSN:1475-6366 DOI  

  Supuran, Claudiu T.; Capasso, Clemente (2016). New light on bacterial carbonic anhydrases phylogeny based on the analysis of signal peptide sequences. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1254-1260, ISSN:1475-6366 DOI  

  Maccallini, Cristina; Di Matteo, Mauro; Vullo, Daniela; Ammazzalorso, Alessandra; Carradori, Simone; De Filippis, Barbara; Fantacuzzi, Marialuigia; Giampietro, Letizia; Pandolfi, Assunta; Supuran, Claudiu T.; Amoroso, Rosa (2016). Indazole, Pyrazole, and Oxazole Derivatives Targeting Nitric Oxide Synthases and Carbonic Anhydrases. CHEMMEDCHEM, vol. 11, pp. 1695-1699, ISSN:1860-7179 DOI   Accesso ONLINE all'editore

  D’Ascenzio, Melissa; Guglielmi, Paolo; Carradori, Simone; Secci, Daniela; Florio, Rosalba; Mollica, Adriano; Ceruso, Mariangela; Akdemir, Atilla; Sobolev, Anatoly P.; Supuran, Claudiu T. (2016). Open saccharin-based secondary sulfonamides as potent and selective inhibitors of cancer-related carbonic anhydrase IX and XII isoforms. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 1-9, ISSN:1475-6366 DOI  

  Nocentini, Alessio; Ferraroni, Marta; Carta, Fabrizio; Ceruso, Mariangela; Gratteri, Paola; Lanzi, Cecilia; Masini, Emanuela; Supuran, Claudiu T (2016). Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations. JOURNAL OF MEDICINAL CHEMISTRY, vol. 59, pp. 10692-10704, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Scozzafava, Andrea; Supuran, Claudiu T; Carta, Fabrizio (2016). Polyamines and α-carbonic anhydrases. MOLECULES, vol. 21, pp. 1726-1735, ISSN:1420-3049 DOI   Accesso ONLINE all'editore

  Modak, Joyanta K.; Liu, Yu.C.; Supuran, Claudiu T.; Roujeinikova, Anna (2016). Structure-Activity Relationship for Sulfonamide Inhibition of Helicobacter pylori α-Carbonic Anhydrase. JOURNAL OF MEDICINAL CHEMISTRY, vol. 59, pp. 11098-11109, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Yamali, Cem; Gul, Halise Inci; Sakagami, Hiroshi; Supuran, Claudiu T. (2016). Synthesis and bioactivities of halogen bearing phenolic chalcones and their corresponding bis Mannich bases. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 125-131, ISSN:1475-6366 DOI  

  Gul, Halise Inci; Mete, Ebru; Eren, Sakip Emre; Sakagami, Hiroshi; Yamali, Cem; Supuran, Claudiu T. (2016). Designing, synthesis and bioactivities of 4-[3-(4-hydroxyphenyl)-5-aryl-4,5-dihydro-pyrazol-1-yl]benzenesulfonamides. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 1-7, ISSN:1475-6366 DOI  

  Krasavin, Mikhail; Stavniichuk, Roman; Zozulya, Sergey; Borysko, Petro; Vullo, Daniela; Supuran, Claudiu T. (2016). Discovery of Strecker-type α-aminonitriles as a new class of human carbonic anhydrase inhibitors using differential scanning fluorimetry. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1707-1711, ISSN:1475-6366 DOI  

  Akocak, Suleyman; Alam, M. Raqibul; Shabana, Ahmed M.; Sanku, Rajesh Kishore Kumar; Vullo, Daniela; Thompson, Harry; Swenson, Erik R.; Supuran, Claudiu T; Ilies, Marc A. (2016). PEGylated Bis-Sulfonamide Carbonic Anhydrase Inhibitors Can Efficiently Control the Growth of Several Carbonic Anhydrase IX-Expressing Carcinomas. JOURNAL OF MEDICINAL CHEMISTRY, vol. 59, pp. 5077-5088, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Mujumdar, Prashant; Teruya, Kanae; Tonissen, Kathryn F.; Vullo, Daniela; Supuran, Claudiu T.; Peat, Thomas S.; Poulsen, Sally-Ann (2016). An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C. JOURNAL OF MEDICINAL CHEMISTRY, vol. 59, pp. 5462-5470, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Burmaoğlu, Serdar; Dilek, Esra; Yılmaz, Ali Osman; Supuran, Claudiu T. (2016). Synthesis of two phloroglucinol derivatives with cinnamyl moieties as inhibitors of the carbonic anhydrase isozymes I and II: an in vitro study. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 208-212, ISSN:1475-6366 DOI  

  Diaz, Jorge R. A.; Fernández Baldo, Martín; Echeverría, Gustavo; Baldoni, Héctor; Vullo, Daniela; Soria, Delia B.; Supuran, Claudiu T.; Camí, Gerardo E (2016). A substituted sulfonamide and its Co (II), Cu (II), and Zn (II) complexes as potential antifungal agents. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 51-62, ISSN:1475-6366 DOI  

  Özbey, Fadime; Taslimi, Parham; Gülçin, İlhami; Maraş, Ahmet; Göksu, Süleyman; Supuran, Claudiu T. (2016). Synthesis of diaryl ethers with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 79-85, ISSN:1475-6366 DOI  

  Costa, Giosuè; Gidaro, Maria Concetta; Vullo, Daniela; Supuran, Claudiu T.; Alcaro, Stefano (2016). Active components of essential oils as anti-obesity potential drugs investigated by in silico techniques. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 64, pp. 5295-5300, ISSN:0021-8561 DOI   Accesso ONLINE all'editore

  Angeli, A; Peat, T.S.; Bartolucci, G.; Nocentini, A.; Supuran, C.T.; Carta, F. (2016). Intramolecular oxidative deselenization of acylselenoureas: a facile synthesis of benzoxazole amides and carbonic anhydrase inhibitors. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 14, pp. 11353-11356, ISSN:1477-0520 DOI   Accesso ONLINE all'editore

  Richichi, B.; Baldoneschi, V.; Burgalassi, S.; Fragai, M.; Vullo, D.; Akdemir, A.; Dragoni, E.; Louka, A.; Mamusa, M.; Monti, D.; Berti, D.; Novellino, E.; Rosa, G. De; Supuran, C.T.; Nativi, C. (2016). A Divalent PAMAM-Based Matrix Metalloproteinase/Carbonic Anhydrase Inhibitor for the Treatment of Dry Eye Syndrome. CHEMISTRY-A EUROPEAN JOURNAL, vol. 22, pp. 1714-1721, ISSN:0947-6539 DOI   Accesso ONLINE all'editore

  Ozgun, Dilan Ozmen; Yamali, Cem; Gul, Halise Inci; Taslimi, Parham; Gulcin, Ilhami; Yanik, Telat; Supuran, Claudiu T. (2016). Inhibitory effects of isatin Mannich bases on carbonic anhydrases, acetylcholinesterase, and butyrylcholinesterase. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1498-1501, ISSN:1475-6366 DOI  

  Zhang, Yan; Legrand, Yves-Marie; Petit, Eddy; Supuran, Claudiu T.; Barboiu, Mihail (2016). Dynamic encapsulation and activation of carbonic anhydrase in multivalent dynameric host matrices. CHEMICAL COMMUNICATIONS, vol. 52, pp. 4053-4055, ISSN:1359-7345 DOI   Accesso ONLINE all'editore

  Alafeefy, Ahmed M; Carta, Fabrizio; Ceruso, Mariangela; Al-Tamimi, Abdul-Malek S; Al-Kahtani, Abdulla A; Supuran, Claudiu T (2016). Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 1402-1407, ISSN:0968-0896 DOI  

  Inci Gul, Halise; Yamali, Cem; Tugce Yasa, Asiye; Unluer, Elif; Sakagami, Hiroshi; Tanc, Muhammet; Supuran, Claudiu T. (2016). Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1375-1380, ISSN:1475-6366 DOI  

  Lomelino, Carrie L.; Mahon, Brian P.; Mckenna, Robert; Carta, Fabrizio; Supuran, Claudiu T. (2016). Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 976-981, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Yamali, Cem; Tugrak, Mehtap; Gul, Halise Inci; Tanc, Muhammet; Supuran, Claudiu T. (2016). The inhibitory effects of phenolic Mannich bases on carbonic anhydrase I and II isoenzymes. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1678-1681, ISSN:1475-6366 DOI  

  Durgun, Mustafa; Turkmen, Hasan; Ceruso, Mariangela; Supuran, Claudiu T. (2016). Synthesis of 4-sulfamoylphenyl-benzylamine derivatives with inhibitory activity against human carbonic anhydrase isoforms I, II, IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 982-988, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Villalba, Maria Luisa; Palestro, Pablo; Ceruso, Mariangela; Gonzalez Funes, Jose L; Talevi, Alan; Bruno Blanch, Luis; Supuran, Claudiu T; Gavernet, Luciana (2016). Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 894-901, ISSN:1464-3391 DOI  

  Petrou, Anthi; Geronikaki, Athina; Terzi, Emine; Guler, Ozen Ozensoy; Tuccinardi, Tiziano; Supuran, Claudiu T. (2016). Inhibition of carbonic anhydrase isoforms I, II, IX and XII with secondary sulfonamides incorporating benzothiazole scaffolds. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1306-1311, ISSN:1475-6366 DOI  

  Del Prete, Sonia; De Luca, Viviana; Vullo, Daniela; Osman, Sameh M.; Alothman, Zeid; Carginale, Vincenzo; Supuran, Claudiu T.; Capasso, Clemente (2016). A new procedure for the cloning, expression and purification of the β-carbonic anhydrase from the pathogenic yeast Malassezia globosa, an anti-dandruff drug target. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1156-1161, ISSN:1475-6366 DOI  

  Orhan, Furkan; Şentürk, Murat; Supuran, Claudiu T. (2016). Interaction of anions with a newly characterized alpha carbonic anhydrase from Halomonas sp. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1119-1123, ISSN:1475-6366 DOI  

  Warren, Ted J.; Van Hook, Matthew J.; Supuran, Claudiu T.; Thoreson, Wallace B. (2016). Sources of protons and a role for bicarbonate in inhibitory feedback from horizontal cells to cones in Ambystoma tigrinum retina. THE JOURNAL OF PHYSIOLOGY, vol. 594, pp. 6661-6677, ISSN:0022-3751 DOI   Accesso ONLINE all'editore

  Bozdag, Murat; Alafeefy, Ahmed M.; Carta, Fabrizio; Ceruso, Mariangela; Al-Tamimi, Abdul-Malek S.; Al-Kahtani, Abdulla A.; Alasmary, Fatmah A.S.; Supuran, Claudiu T (2016). Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 4100-4107, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Supuran, Claudiu T (2016). Structure and function of carbonic anhydrases. BIOCHEMICAL JOURNAL, vol. 473, pp. 2023-2032, ISSN:0264-6021 DOI   Accesso ONLINE all'editore

  Xanthopoulos, Dimitrios; Kritsi, Eftichia; Supuran, Claudiu T.; Papadopoulos, Manthos G.; Leonis, Georgios; Zoumpoulakis, Panagiotis (2016). Discovery of HIV Type 1 Aspartic Protease Hit Compounds through Combined Computational Approaches. CHEMMEDCHEM, vol. 11, pp. 1646-1652, ISSN:1860-7179 DOI   Accesso ONLINE all'editore

  Licsandru, Erol; Tanc, Muhammet; Kocsis, Istvan; Barboiu, Mihail; Supuran, Claudiu T. (2016). A class of carbonic anhydrase I – selective activators. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 32, pp. 1-10, ISSN:1475-6366 DOI  

  van Kuijk, Simon J.A; Parvathaneni, Nanda Kumar; Niemans, Raymon; van Gisbergen, Marike W.; Carta, Fabrizio; Vullo, Daniela; Pastorekova, Silvia; Yaromina, Ala; Supuran, Claudiu T.; Dubois, Ludwig J.; Winum, Jean-Yves; Lambin, Philippe (2016). New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 127, pp. 691-702, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Logsdon, Derek P.; Grimard, Michelle; Luo, Meihua; Shahda, Safi; Jiang, Yanlin; Tong, Yan; Yu, Zhangsheng; Zyromski, Nicholas; Schipani, Ernestina; Carta, Fabrizio; Supuran, Claudiu T.; Korc, Murray; Ivan, Mircea; Kelley, Mark R.; Fishel, Melissa L. (2016). Regulation of HIF1a under hypoxia by APE1/Ref-1 impacts CA9 expression: Dual targeting in patient-derived 3D pancreatic cancer models. MOLECULAR CANCER THERAPEUTICS, vol. 15, pp. 2722-2732, ISSN:1535-7163 DOI   Accesso ONLINE all'editore

  Zhang, Yan; Feng, Wei-Xu; Legrand, Yves-Marie; Supuran, Claudiu T.; Su, Cheng-Yong; Barboiu, Mihail (2016). Dynameric host frameworks for the activation of lipase through H-bond and interfacial encapsulation. CHEMICAL COMMUNICATIONS, vol. 52, pp. 13768-13770, ISSN:1359-7345 DOI   Accesso ONLINE all'editore

  Arslan, Tayfun; Türkoğlu, Emir Alper; Şentürk, Murat; Supuran, Claudiu T. (2016). Synthesis and carbonic anhydrase inhibitory properties of novel chalcone substituted benzenesulfonamides. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 26, pp. 5867-5870, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Karioti, Anastasia; Carta, Fabrizio; Supuran, Claudiu T. (2016). Phenols and polyphenols as Carbonic anhydrase inhibitors. MOLECULES, vol. 21, pp. 1649-1676, ISSN:1420-3049 DOI   Accesso ONLINE all'editore

  Kucukoglu, Kaan; Oral, Fatih; Aydin, Tevfik; Yamali, Cem; Algul, Oztekin; Sakagami, Hiroshi; Gulcin, Ilhami; Supuran, Claudiu T.; Gul, Halise Inci (2016). Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 20-24, ISSN:1475-6366 DOI  

  Del Prete, Sonia; De Luca, Viviana; De Simone, Giuseppina; Supuran, Claudiu T.; Capasso, Clemente (2016). Cloning, expression and purification of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 54-59, ISSN:1475-6366 DOI  

  Arias-Hidalgo, Mariela; Hegermann, Jan; Tsiavaliaris, Georgios; Carta, Fabrizio; Supuran, Claudiu T.; Gros, Gerolf; Endeward, Volker (2016). CO2 and HCO3- Permeability of the Rat Liver Mitochondrial Membrane. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, vol. 39, pp. 2014-2024, ISSN:1015-8987 DOI   Accesso ONLINE all'editore

  Alterio, Vincenzo; Cadoni, Roberta; Esposito, Davide; Vullo, Daniela; Fiore, Anna Di; Monti, Simona Maria; Caporale, Andrea; Ruvo, Menotti; Sechi, Mario; Dumy, Pascal; Supuran, Claudiu T.; Simone, Giuseppina De; Winum, Jean-Yves (2016). Benzoxaborole as a new chemotype for carbonic anhydrase inhibition. CHEMICAL COMMUNICATIONS, vol. 52, pp. 11983-11986, ISSN:1359-7345 DOI   Accesso ONLINE all'editore

  Göksu, Haydar; Topal, Meryem; Keskin, Ali; Gültekin, Mehmet S.; Çelik, Murat; Gülçin, Ilhami; Tanc, Muhammet; Supuran, Claudiu T. (2016). 9,10-Dibromo-N-aryl-9,10-dihydro-9,10-[3,4]epipyrroloanthracene-12,14-diones: Synthesis and Investigation of Their Effects on Carbonic Anhydrase Isozymes I, II, IX, and XII. ARCHIV DER PHARMAZIE, vol. 349, pp. 466-474, ISSN:0365-6233 DOI   Accesso ONLINE all'editore

  Supuran, Claudiu T (2016). Carbonic anhydrase inhibition and the management of neuropathic pain. EXPERT REVIEW OF NEUROTHERAPEUTICS, vol. 16, pp. 961-968, ISSN:1473-7175 DOI  

  Abdel Gawad, Nagwa M.; Amin, Noha H.; Elsaadi, Mohammed T.; Mohamed, Fatma M.M.; Angeli, Andrea; De Luca, Viviana; Capasso, Clemente; Supuran, Claudiu T (2016). Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 3043-3051, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Kã¼ã§ã¼kbay, F. Zehra; Kã¼ã§ã¼kbay, Hasan; Tanc, Muhammet; Supuran, Claudiu T. (2016). Synthesis and carbonic anhydrase I, II, IV and XII inhibitory properties of N-protected amino acid – sulfonamide conjugates. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1476-1483, ISSN:1475-6366 DOI  

  Bozdag, Murat; Carta, Fabrizio; Vullo, Daniela*; Isik, Semra; AlOthman, Zeid; Osman, Sameh M.; Scozzafava, Andrea; Supuran, Claudiu T. (2016). Dithiocarbamates with potent inhibitory activity against the Saccharomyces cerevisiae β-carbonic anhydrase. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 132-136, ISSN:1475-6366 DOI  

  Alafeefy, Ahmed M.; Ahmad, Rehan; Abdulla, Maha; Eldehna, Wagdy M.; Al-Tamimi, Abdul-Malek S.; Abdel-Aziz, Hatem A.; Al-Obaid, Omar; Carta, Fabrizio; Al-Kahtani, Abdulla A.; Supuran, Claudiu T. (2016). Development of certain new 2-substituted-quinazolin-4-ylaminobenzenesulfonamide as potential antitumor agents. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 109, pp. 247-253, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Kalinin, Stanislav; Supuran, Claudiu T.; Krasavin, Mikhail (2016). Multicomponent chemistry in the synthesis of carbonic anhydrase inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 185-199, ISSN:1475-6366 DOI  

  Annunziato G.; Angeli A.; D'Alba F.; Bruno A.; Pieroni M.; Vullo D.; De Luca V.; Capasso C.; Supuran C.T.; Costantino G. (2016). Cover Picture: Discovery of New Potential Anti-Infective Compounds Based on Carbonic Anhydrase Inhibitors by Rational Target-Focused Repurposing Approaches (ChemMedChem 17/2016). CHEMMEDCHEM, vol. 11, pp. 1876-1876, ISSN:1860-7179 DOI   Accesso ONLINE all'editore

  Carta, Fabrizio; Ferraroni, Marta; Scozzafava, Andrea; Supuran, Claudiu T (2016). Fluorescent sulfonamide carbonic anhydrase inhibitors incorporating 1,2,3-triazole moieties: Kinetic and X-ray crystallographic studies. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 104-12-112, ISSN:0968-0896 DOI  

  Del Prete, Sonia; De Luca, Viviana; Capasso, Clemente; Supuran, Claudiu T; Carginale, Vincenzo (2016). Recombinant thermoactive phosphoenolpyruvate carboxylase (PEPC) from Thermosynechococcus elongatus and its coupling with mesophilic/thermophilic bacterial carbonic anhydrases (CAs) for the conversion of CO2 to oxaloacetate. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 220-5-225, ISSN:0968-0896 DOI  

  Eminoğlu, Ayşenur; Vullo, Daniela; Aşık, Aycan; Çolak, Dilşat Nigar; Supuran, Claudiu T; Çanakçı, Sabriye; Osman Beldüz, Ali (2016). Cloning, expression and biochemical characterization of a β-carbonic anhydrase from the soil bacterium Enterobacter sp. B13. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1111-1118, ISSN:1475-6366 DOI  

  Vullo, Daniela; De Luca, Viviana; Del Prete, Sonia; Carginale, Vincenzo; Scozzafava, Andrea; Osman, Sameh M.; Alothman, Zeid; Capasso, Clemente; Supuran, Claudiu T. (2016). Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 26, pp. 1253-1259, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Vullo, Daniela; Durante, Mariaconcetta; Di Leva, Francesco Saverio; Cosconati, Sandro; Masini, Emanuela; Scozzafava, Andrea; Novellino, Ettore; Supuran, Claudiu T.; Carta, Fabrizio (2016). Monothiocarbamates Strongly Inhibit Carbonic Anhydrases in Vitro and Possess Intraocular Pressure Lowering Activity in an Animal Model of Glaucoma. JOURNAL OF MEDICINAL CHEMISTRY, vol. 59, pp. 5857-5867, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Del Prete, Sonia; Vullo, Daniela; De Luca, Viviana; Carginale, Vincenzo; Ferraroni, Marta; Osman, Sameh M.; Alothman, Zeid; Supuran, Claudiu T.; Capasso, Clemente (2016). Sulfonamide inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 1115-1120, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Vullo, Daniela; Del Prete, Sonia; De Luca, Viviana; Carginale, Vincenzo; Ferraroni, Marta; Dedeoglu, Nurcan; Osman, Sameh M.; Alothman, Zeid; Capasso, Clemente; Supuran, Claudiu T. (2016). Anion inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 26, pp. 1406-1410, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Ferraroni, Marta; Carta, Fabrizio; Scozzafava, Andrea; Supuran, Claudiu T. (2016). Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to Coumarins. JOURNAL OF MEDICINAL CHEMISTRY, vol. 59, pp. 462-473, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Cornelio, Benedetta; Laronze Cochard, Marie; Ceruso, Mariangela; Ferraroni, Marta; Rance, Graham A.; Carta, Fabrizio; Khlobystov, Andrei N.; Fontana, Antonella; Supuran, CLAUDIU TRANDAFIR; Sapi, Janos (2016). 4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies. JOURNAL OF MEDICINAL CHEMISTRY, vol. 59, pp. 721-732, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Vullo, Daniela; Supuran, Claudiu T.; Scozzafava, Andrea; De Simone, Giuseppina; Monti, Simona Maria; Alterio, Vincenzo; Carta, Fabrizio (2016). Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine–benzenesulfonamides acting as carbonic anhydrase inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 3643-3648, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Margheri, F; Ceruso, M; Carta, F; Laurenzana, A; Maggi, L; Lazzeri, S; Simonini, G; Annunziato, F; Del Rosso, M; Supuran, CT; Cimaz, R (2016). Overexpression of the transmembrane carbonic anhydrase isoforms IX and XII in the inflamed synovium. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 0-0, ISSN:1475-6366 DOI  

  Küçükbay, F. Zehra; Buğday, Nesrin; Küçükbay, Hasan; Tanc, Muhammet; Supuran, Claudiu T. (2016). Synthesis, characterization and carbonic anhydrase inhibitory activity of novel benzothiazole derivatives. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1221-1225, ISSN:1475-6366 DOI  

  Küçükbay, F. Zehra; Küçükbay, Hasan; Tanc, Muhammet; Supuran, Claudiu T (2016). Synthesis and carbonic anhydrase inhibitory properties of amino acid – coumarin/quinolinone conjugates incorporating glycine, alanine and phenylalanine moieties. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1198-1202, ISSN:1475-6366 DOI  

  Langella, Emma; D'Ambrosio, Katia; D'Ascenzio, Melissa; Carradori, Simone; Monti, Simona M.; Supuran, Claudiu T.; De Simone, Giuseppina (2016). A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic Anhydrases. CHEMISTRY-A EUROPEAN JOURNAL, vol. 22, pp. 97-100, ISSN:0947-6539 DOI   Accesso ONLINE all'editore

  Supuran, Claudiu T (2016). How many carbonic anhydrase inhibition mechanisms exist?. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 345-360, ISSN:1475-6366 DOI  

  Karioti, Anastasia; Carta, Fabrizio; Supuran, Claudiu (2016). An Update on Natural Products with Carbonic Anhydrase Inhibitory Activity. CURRENT PHARMACEUTICAL DESIGN, vol. 22, pp. 1570-1591, ISSN:1381-6128 DOI  

  Mete, Ebru; Comez, Birnur; Inci Gul, Halise; Gulcin, Ilhami; Supuran, Claudiu T. (2016). Synthesis and carbonic anhydrase inhibitory activities of new thienyl-substituted pyrazoline benzenesulfonamides. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1-5, ISSN:1475-6366 DOI  

  Lomelino, Carrie L.; Supuran, Claudiu T.; Mckenna, Robert (2016). Non-classical inhibition of carbonic anhydrase. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 17, pp. 1150-1162, ISSN:1661-6596 DOI   Accesso ONLINE all'editore

  Supuran, Claudiu T (2016). CA IX stratification based on cancer treatment: a patent evaluation of US2016/0002350. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 26, pp. 1105-1109, ISSN:1354-3776 DOI  

  Riafrecha, Leonardo E.; Bua, Silvia; Supuran, Claudiu T.; Colinas, Pedro A. (2016). Synthesis and carbonic anhydrase inhibitory effects of new N-glycosylsulfonamides incorporating the phenol moiety. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 26, pp. 3892-3895, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Zolfaghari Emameh, Reza; Barker, Harlan R.; Syrjänen, Leo; Urbański, Linda; Supuran, Claudiu T.; Parkkila, Seppo (2016). Identification and inhibition of carbonic anhydrases from nematodes. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 176-184, ISSN:1475-6366 DOI  

  Cau, Ylenia; Mori, Mattia; Supuran, Claudiu T; Botta, Maurizio (2016). Mycobacterial carbonic anhydrase inhibition with phenolic acids and esters: Kinetic and computational investigations. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 14, pp. 8322-8330, ISSN:1477-0520 DOI   Accesso ONLINE all'editore

  Aygul, Imdat; Yaylaci Karahalil, Fatma; Supuran, Claudiu T. (2016). Investigation of the inhibitory properties of some phenolic standards and bee products against human carbonic anhydrase I and II. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 119-124, ISSN:1475-6366 DOI  

  Durdagi, Serdar; Korkmaz, Neslihan; Işık, Semra; Vullo, Daniela; Astley, Demet; Ekinci, Deniz; Salmas, Ramin E.; Senturk, Murat; Supuran, Claudiu T. (2016). Kinetic and docking studies of cytosolic/tumor-associated carbonic anhydrase isozymes I, II and IX with some hydroxylic compounds. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1214-1220, ISSN:1475-6366 DOI  

  Yaseen, Raed; Ekinci, Deniz; Senturk, Murat; Hameed, Alhamzah Dh.; Ovais, Syed; Rathore, Pooja; Samim, Mohammed; Javed, Kalim; Supuran, Claudiu T. (2016). Pyridazinone substituted benzenesulfonamides as potent carbonic anhydrase inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 26, pp. 1337-1341, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Supuran, Claudiu T (2016). Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, vol. 12, pp. 423-431, ISSN:1742-5255 DOI  

  Supuran, Claudiu T (2016). Inhibition of carbonic anhydrase from Trypanosoma cruzi for the management of Chagas disease: An underexplored therapeutic opportunity. FUTURE MEDICINAL CHEMISTRY, vol. 8, pp. 311-324, ISSN:1756-8919 DOI   Accesso ONLINE all'editore

  Alderman, Sarah L; Harter, Till S.; Wilson, Jonathan M.; Supuran, Claudiu T.; Farrell, Anthony P.; Brauner, Colin J. (2016). Evidence for a plasma-accessible carbonic anhydrase in the lumen of salmon heart that may enhance oxygen delivery to the myocardium. JOURNAL OF EXPERIMENTAL BIOLOGY, vol. 219, pp. 719-724, ISSN:0022-0949 DOI   Accesso ONLINE all'editore

  Gul, Halise Inci; Yazici, Zehra; Tanc, Muhammet; Supuran, Claudiu T. (2016). Inhibitory effects of benzimidazole containing new phenolic Mannich bases on human carbonic anhydrase isoforms hCA I and II. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1540-1544, ISSN:1475-6366 DOI  

  Sujayev, Afsun; Garibov, Emin; Taslimi, Parham; Gulã§in, İlhami; Gojayeva, Sevinj; Farzaliyev, Vagif; Alwasel, Saleh H.; Supuran, Claudiu T. (2016). Synthesis of some tetrahydropyrimidine-5-carboxylates, determination of their metal chelating effects and inhibition profiles against acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1531-1539, ISSN:1475-6366 DOI  

  Özgeris¸, Bünyamin; Göksu, Süleyman; Polat Köse, Leyla; Gülçin, Ilhami; Salmas, Ramin Ekhteiari; Durdagi, Serdar; Tümer, Ferhan; Supuran, Claudiu T. (2016). Acetylcholinesterase and carbonic anhydrase inhibitory properties of novel urea and sulfamide derivatives incorporating dopaminergic 2-aminotetralin scaffolds. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 2318-2329, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Capasso, Clemente; Supuran, Claudiu (2016). An Overview of the Carbonic Anhydrases from Two Pathogens of the Oral Cavity: Streptococcus mutans and Porphyromonas gingivalis. CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol. 16, pp. 2359-2368, ISSN:1568-0266 DOI  

  Chandak, Navneet; Ceruso, Mariangela; Supuran, Claudiu T; Sharma, Pawan K. (2016). Novel sulfonamide bearing coumarin scaffolds as selective inhibitors of tumor associated carbonic anhydrase isoforms IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 2882-2886, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Federici, Cristina; Lugini, Luana; Marino, Maria Lucia; Carta, Fabrizio; Iessi, Elisabetta; Azzarito, Tommaso; Supuran, Claudiu T.; Fais, Stefano (2016). Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 119-125, ISSN:1475-6366 DOI  

  Zoccola, Didier; Innocenti, Alessio; Bertucci, Anthony; Tambutté, Eric; Supuran, Claudiu T.; Tambutté, Sylvie (2016). Coral carbonic anhydrases: Regulation by ocean acidification. MARINE DRUGS, vol. 14, pp. 109-119, ISSN:1660-3397 DOI   Accesso ONLINE all'editore

  Nocentini, Alessio; Vullo, Daniela; Bartolucci, Gianluca; Supuran, Claudiu T (2016). N-Nitrosulfonamides: A new chemotype for carbonic anhydrase inhibition. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 3612-3617, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Ulus, Ramazan; Aday, Burak; Tanç, Muhammet; Supuran, Claudiu T; Kaya, Muharrem (2016). Microwave assisted synthesis of novel acridine–acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 3548-3555, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Annunziato, Giannamaria; Angeli, Andrea; D'Alba, Francesca; Bruno, Agostino; Pieroni, Marco; Vullo, Daniela; De Luca, Viviana; Capasso, Clemente; Supuran, Claudiu T.; Costantino, Gabriele (2016). Discovery of New Potential Anti-Infective Compounds Based on Carbonic Anhydrase Inhibitors by Rational Target-Focused Repurposing Approaches. CHEMMEDCHEM, vol. 11, pp. 1904-1914, ISSN:1860-7179 DOI   Accesso ONLINE all'editore

  Coviello, Vito; Marchi, Beatrice; Sartini, Stefania; Quattrini, Luca; Marini, Anna Maria; Simorini, Francesca; Taliani, Sabrina; Salerno, Silvia; Orlandi, Paola; Fioravanti, Anna; Desidero, Teresa Di; Vullo, Daniela; Da Settimo, Federico; Supuran, Claudiu T; Bocci, Guido; La Motta, Concettina (2016). 1,2-Benzisothiazole Derivatives Bearing 4-, 5-, or 6-Alkyl/arylcarboxamide Moieties Inhibit Carbonic Anhydrase Isoform IX (CAIX) and Cell Proliferation under Hypoxic Conditions. JOURNAL OF MEDICINAL CHEMISTRY, vol. 59, pp. 6547-6552, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Sneddon, Deborah; Niemans, Raymon; Bauwens, Matthias; Yaromina, Ala; Van Kuijk, Simon J. A.; Lieuwes, Natasja G.; Biemans, Rianne; Pooters, Ivo; Pellegrini, Paul A.; Lengkeek, Nigel A.; Greguric, Ivan; Tonissen, Kathryn F.; Supuran, Claudiu T.; Lambin, Philippe; Dubois, Ludwig; Poulsen, Sally-Ann (2016). Synthesis and in Vivo Biological Evaluation of 68Ga-Labeled Carbonic Anhydrase IX Targeting Small Molecules for Positron Emission Tomography. JOURNAL OF MEDICINAL CHEMISTRY, vol. 59, pp. 6431-6443, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Supuran, Claudiu T (2016). Legionella pneumophila Carbonic Anhydrases: Underexplored Antibacterial Drug Targets. PATHOGENS, vol. 5, pp. 44-59, ISSN:2076-0817 DOI  

  Garibov, Emin; Taslimi, Parham; Sujayev, Afsun; Bingol, Zeynebe; Çetinkaya, Songul; Gulçin, İlhami; Beydemir, Sukru; Farzaliyev, Vagif; Alwasel, Saleh H.; Supuran, Claudiu T. (2016). Synthesis of 4,5-disubstituted-2-thioxo-1,2,3,4-tetrahydropyrimidines and investigation of their acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase I/II inhibitory and antioxidant activities. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1-9, ISSN:1475-6366 DOI  

  El-Azab, Adel S.; Abdel-Aziz, Alaa A.-M.; Ayyad, Rezk R.; Ceruso, Mariangela; Supuran, Claudiu T. (2016). Inhibition of carbonic anhydrase isoforms I, II, IV, VII and XII with carboxylates and sulfonamides incorporating phthalimide/phthalic anhydride scaffolds. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 20-25, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Gülçin, İlhami; Scozzafava, Andrea; Supuran, Claudiu T.; Koksal, Zeynep; Turkan, Fikret; Çetinkaya, Songül; Bingöl, Zeynebe; Huyut, Zübeyir; Alwasel, Saleh H. (2016). Rosmarinic acid inhibits some metabolic enzymes including glutathione S-transferase, lactoperoxidase, acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase isoenzymes. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 1-5, ISSN:1475-6366 DOI  

  Artunç, Tekin; Çetinkaya, Yasin; Göçer, Hülya; Gülçin, Ilhami; Menzek, Abdullah; Şahin, Ertan; Supuran, Claudiu T. (2016). Synthesis of 4-[2-(3,4-dimethoxybenzyl)cyclopentyl]-1,2-dimethoxybenzene Derivatives and Evaluations of Their Carbonic Anhydrase Isoenzymes Inhibitory Effects. CHEMICAL BIOLOGY & DRUG DESIGN, vol. 87, pp. 594-607, ISSN:1747-0277 DOI   Accesso ONLINE all'editore

  Nocentini, Alessio; Ceruso, Mariangela; Carta, Fabrizio; Supuran, Claudiu T. (2016). 7-Aryl-triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrase IX and XII. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1226-1233, ISSN:1475-6366 DOI  

  Sujayev, Afsun; Polat Kose, Leyla; Garibov, Emin; Gülçin, İlhami; Farzaliev, Vagif; Alwasel, Saleh H.; Supuran, Claudiu T. (2016). Synthesis of N-alkyl (aril)-tetra pyrimidine thiones and investigation of their human carbonic anhydrase I and II inhibitory effects. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1192-1197, ISSN:1475-6366 DOI  

  Kose, Leyla Polat; Gulcin, İlhami; Yıldırım, Alper; Atmaca, Ufuk; Çelik, Murat; Alwasel, Saleh H.; Supuran, Claudiu T. (2016). The human carbonic anhydrase isoenzymes I and II inhibitory effects of some hydroperoxides, alcohols, and acetates. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1248-1253, ISSN:1475-6366 DOI  

  Ameis, Helen M.; Drenckhan, Astrid; Freytag, Morton; Izbicki, Jakob R.; Supuran, Claudiu T.; Reinshagen, Konrad; Holland-Cunz, Stefan; Gros, Stephanie J. (2016). Influence of hypoxia-dependent factors on the progression of neuroblastoma. PEDIATRIC SURGERY INTERNATIONAL, vol. 32, pp. 187-192, ISSN:0179-0358 DOI   Accesso ONLINE all'editore

  Del Prete, Sonia; Vullo, Daniela; De Luca, Viviana; Carginale, Vincenzo; Osman, Sameh M.; Alothman, Zeid; Supuran, Claudiu T.; Capasso, Clemente (2016). Cloning, expression, purification and sulfonamide inhibition profile of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 26, pp. 4184-4190, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Supuran, Claudiu T (2016). Bortezomib inhibits bacterial and fungal β-carbonic anhydrases. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 4406-4409, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Del Prete, Sonia; Vullo, Daniela; De Luca, Viviana; Carginale, Vincenzo; di Fonzo, Pietro; Osman, Sameh M.; Alothman, Zeid; Supuran, Claudiu T.; Capasso, Clemente (2016). Anion inhibition profiles of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 4410-4414, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Unluer, Elif; Gul, Halise Inci; Demirtas, Alkan; Sakagami, Hiroshi; Umemura, Naoki; Tanc, Muhammet; Kazaz, Cavit; Supuran, Claudiu T. (2016). Synthesis and bioactivity studies of 1-aryl-3-(2-hydroxyethylthio)-1-propanones. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 105-109, ISSN:1475-6366 DOI  

  Mollica, Adriano; Locatelli, Marcello; Macedonio, Giorgia; Carradori, Simone; Sobolev, Anatoly P.; De Salvador, Roberto F.; Monti, Simona M.; Buonanno, Martina; Zengin, Gokhan; Angeli, Andrea; Supuran, Claudiu T. (2016). Microwave-assisted extraction, HPLC analysis, and inhibitory effects on carbonic anhydrase I, II, VA, and VII isoforms of 14 blueberry Italian cultivars. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1-6, ISSN:1475-6366 DOI  

  Supuran, Claudiu T (2016). Bortezomib inhibits mammalian carbonic anhydrases. BIOORGANIC & MEDICINAL CHEMISTRY, pp. 1-4, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  De Luca, Viviana; Vullo, Daniela; Del Prete, Sonia; Carginale, Vincenzo; Osman, Sameh M.; Alothman, Zeid; Supuran, Claudiu T.; Capasso, Clemente (2016). Cloning, characterization and anion inhibition studies of a γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 835-840, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Barresi, Elisabetta; Salerno, Silvia; Marini, Anna Maria; Taliani, Sabrina; La Motta, Concettina; Simorini, Francesca; Da Settimo, Federico; Vullo, Daniela; Supuran, Claudiu T. (2016). Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 921-927, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Carradori, Simone; Secci, Daniela; De Monte, Celeste; Mollica, Adriano; Ceruso, Mariangela; Akdemir, Atilla; Sobolev, Anatoly P.; Codispoti, Rossella; De Cosmi, Federica; Guglielmi, Paolo; Supuran, Claudiu T. (2016). A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 1095-1105, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Lau, Joseph; Zhang, Zhengxing; Jenni, Silvia; Kuo, Hsiou-Ting; Liu, Zhibo; Vullo, Daniela; Supuran, Claudiu T.; Lin, Kuo-Shyan; Bénard, François (2016). PET Imaging of Carbonic Anhydrase IX Expression of HT-29 Tumor Xenograft Mice with 68Ga-Labeled Benzenesulfonamides. MOLECULAR PHARMACEUTICS, vol. 13, pp. 1137-1146, ISSN:1543-8384 DOI   Accesso ONLINE all'editore

  Eldehna, Wagdy M; Fares, Mohamed; Ceruso, Mariangela; Ghabbour, Hazem A.; Abou-Seri, Sahar M.; Abdel-Aziz, Hatem A.; Abou El Ella, Dalal A.; Supuran, Claudiu T. (2016). Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 110, pp. 259-266, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Bruno, Elvira; Buemi, Maria R.; De Luca, Laura; Ferro, Stefania; Monforte, Anna-Maria; Supuran, Claudiu T.; Vullo, Daniela; De Sarro, Giovambattista; Russo, Emilio; Gitto, Rosaria (2016). In Vivo Evaluation of Selective Carbonic Anhydrase Inhibitors as Potential Anticonvulsant Agents. CHEMMEDCHEM, vol. 11, pp. 1812-1818, ISSN:1860-7179 DOI   Accesso ONLINE all'editore

  Eminoğlu, Ayşenur; Vullo, Daniela; Aşık, Aycan; Çolak, Dilşat Nigar; Çanakçı, Sabriye; Beldüz, Ali Osman; Supuran, Claudiu T. (2016). Sulfonamide inhibition studies of the β-carbonic anhydrase from the newly discovered bacterium Enterobacter sp. B13. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 26, pp. 1821-1826, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Akdemir, Atilla; Güzel-Akdemir, Özlen; Karali, Nilgün; Supuran, Claudiu T. (2016). Isatin analogs as novel inhibitors of Candida spp. β-carbonic anhydrase enzymes. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 24, pp. 1648-1652, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Yılmaz, Sã¼leyman; Akbaba, Yusuf; Ã-zgeriş, Bã¼nyamin; Kã¶se, Leyla Polat; Gã¶ksu, Sã¼leyman; Gã¼lã§in, İlhami; Alwasel, Saleh H.; Supuran, Claudiu T. (2016). Synthesis and inhibitory properties of some carbamates on carbonic anhydrase and acetylcholine esterase. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 1484-1491, ISSN:1475-6366 DOI  

  M. Tanc;F. Carta;A. Scozzafava;C. T. Supuran (2015). 6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA.. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 13, pp. 77-80, ISSN:1477-0520 DOI   Accesso ONLINE all'editore

  A. Scozzafava;P. Kalın;C. T. Supuran;İ. Gülçin;S. H. Alwasel (2015). The impact of hydroquinone on acetylcholine esterase and certain human carbonic anhydrase isoenzymes (hCA I, II, IX, and XII).. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 14, pp. 1-6, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Del Prete, Sonia; De Luca, Viviana; Iandolo, Elena; Supuran, Claudiu T.; Capasso, Clemente (2015). Protonography, a powerful tool for analyzing the activity and the oligomeric state of the γ-carbonic anhydrase identified in the genome of Porphyromonas gingivalis. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 3747-3750, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Abellán-Flos, Marta; Tanç, Muhammet; Supuran, Claudiu T.; Vincent, Stéphane P. (2015). Exploring carbonic anhydrase inhibition with multimeric coumarins displayed on a fullerene scaffold. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 13, pp. 7445-7451, ISSN:1477-0520 DOI   Accesso ONLINE all'editore

  Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Balboni, Gianfranco; Ceruso, Mariangela; Supuran, Claudiu T. (2015). Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 5619-25-5625, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Mori, Mattia; Cau, Ylenia; Vignaroli, Giulia; Laurenzana, Ilaria; Caivano, Antonella; Vullo, Daniela; Supuran, Claudiu T.; Botta, Maurizio (2015). Hit Recycling: Discovery of a Potent Carbonic Anhydrase Inhibitor by in Silico Target Fishing. ACS CHEMICAL BIOLOGY, vol. 10, pp. 1964-1969, ISSN:1554-8929 DOI   Accesso ONLINE all'editore

  Supuran, Claudiu T.; Capasso, Clemente (2015). The η-class carbonic anhydrases as drug targets for antimalarial agents. EXPERT OPINION ON THERAPEUTIC TARGETS, vol. 19, pp. 551-563, ISSN:1472-8222 DOI   Accesso ONLINE all'editore

  Esirden, İbrahim; Ulus, Ramazan; Aday, Burak; Tanç, Muhammet; Supuran, Claudiu T; Kaya, Muharrem (2015). Synthesis of novel acridine bis-sulfonamides with effective inhibitory activity against the carbonic anhydrase isoforms I, II, IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 6573-80-6580, ISSN:0968-0896 DOI  

  Vullo, Daniela; De Luca, Viviana; Del Prete, Sonia; Carginale, Vincenzo; Scozzafava, Andrea; Capasso, Clemente; Supuran, Claudiu T. (2015). Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 1728-1734, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Ibrahim, Hany S; Abou-Seri, Sahar M; Tanc, Muhammet; Elaasser, Mahmoud M; Abdel-Aziz, Hatem A; Supuran, Claudiu T (2015). Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 103, pp. 583-93-593, ISSN:0223-5234 DOI  

  Bozdag, Murat; Isik, Semra; Beyaztas, Serap; Arslan, Oktay; Supuran, Claudiu T. (2015). Synthesis of a novel affinity gel for the purification of carbonic anhydrases. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 240-244, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Balboni, Gianfranco; Dedeoglu, Nurcan; Supuran, Claudiu T. (2015). Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 25, pp. 3850-3853, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Lau, Joseph; Liu, Zhibo; Lin, Kuo-Shyan; Pan, Jinhe; Zhang, Zhengxing; Vullo, Daniela; Supuran, Claudiu T.; Perrin, David M.; Bénard, François (2015). Trimeric radiofluorinated sulfonamide derivatives to achieve in vivo selectivity for carbonic anhydrase IX-targeted PET imaging. THE JOURNAL OF NUCLEAR MEDICINE, vol. 56, pp. 1434-1440, ISSN:0161-5505 DOI   Accesso ONLINE all'editore

  Dedeoglu, Nurcan; Deluca, Viviana; Isik, Semra; Yildirim, Hatice; Kockar, Feray; Capasso, Clemente; Supuran, Claudiu T. (2015). Sulfonamide inhibition study of the β-class carbonic anhydrase from the caries producing pathogen Streptococcus mutans. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 25, pp. 2291-2297, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Shi, Qi; Kaiser, Thomas M.; Dentmon, Zackery W.; Ceruso, Mariangela; Vullo, Daniela; Supuran, Claudiu T.; Snyder, James P. (2015). Design and validation of FRESH, a drug discovery paradigm resting on robust chemical synthesis. ACS MEDICINAL CHEMISTRY LETTERS, vol. 6, pp. 518-522, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Carta, Fabrizio; Osman, Sameh M.; Vullo, Daniela; Alothman, Zeid; Supuran, Claudiu T. (2015). Dendrimers incorporating benzenesulfonamide moieties strongly inhibit carbonic anhydrase isoforms I-XIV. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 13, pp. 6453-6457, ISSN:1477-0520 DOI   Accesso ONLINE all'editore

  Güzel-Akdemir, Özlen; Akdemir, Atilla; Karali, Nilgün; Supuran, Claudiu T. (2015). Discovery of novel isatin-based sulfonamides with potent and selective inhibition of the tumor-associated carbonic anhydrase isoforms IX and XII. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 13, pp. 6493-6499, ISSN:1477-0520 DOI   Accesso ONLINE all'editore

  Tanpure, Rajendra P; Ren, Bin; Peat, Thomas S.; Bornaghi, Laurent F.; Vullo, Daniela; Supuran, Claudiu T.; Poulsen, Sally-Ann (2015). Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site. JOURNAL OF MEDICINAL CHEMISTRY, vol. 58, pp. 1494-1501, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Tanc, Muhammet; Carta, Fabrizio; Scozzafava, Andrea; Supuran, Claudiu T. (2015). α-carbonic anhydrases possess thioesterase activity. ACS MEDICINAL CHEMISTRY LETTERS, vol. 6, pp. 292-295, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Ceruso, Mariangela; Bragagni, Marco; Alothman, Zeid; Osman, Sameh M.; Supuran, Claudiu T. (2015). New series of sulfonamides containing amino acid moiety act as effective and selective inhibitors of tumor-associated carbonic anhydrase XII. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 430-434, ISSN:1475-6366 DOI  

  De Simone, Giuseppina; Monti, Simona Maria; Alterio, Vincenzo; Buonanno, Martina; De Luca, Viviana; Rossi, Mosè; Carginale, Vincenzo; Supuran, Claudiu T; Capasso, Clemente; Di Fiore, Anna (2015). Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 25, pp. 2002-2006, ISSN:1464-3405 DOI  

  Reich, Reuven; Hoffman, Amnon; Suresh, R. Rama; Shai, Ofra; Frant, Julia; Maresca, Alfonso; Supuran, Claudiu T.; Breuer, Eli (2015). Carbamoylphosphonates inhibit autotaxin and metastasis formation in vivo. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 767-772, ISSN:1475-6366 DOI  

  Gülçin, İlhami; Scozzafava, Andrea; Supuran, Claudiu T; Akıncıoğlu, Hulya; Koksal, Zeynep; Turkan, Fikret; Alwasel, Saleh (2015). The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, lactoperoxidase, and carbonic anhydrase isoenzymes I, II, IX, and XII. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 1-7-7, ISSN:1475-6366 DOI  

  Capasso, Clemente; Supuran, Claudiu T. (2015). An overview of the alpha-, beta- and gamma-carbonic anhydrases from Bacteria: Can bacterial carbonic anhydrases shed new light on evolution of bacteria?. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 325-332, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Pérez-Sayáns, Mario; Suárez-Peñaranda, J.M.; Torres-López, M.; Supuran, C.T.; Gándara-Vila, P.; Gayoso-Diz, P.; Barros-Angueira, F.; Gallas-Torreira, M.; García-García, A. (2015). The use of CA-IX as a diagnostic method for oral leukoplakia. BIOTECHNIC & HISTOCHEMISTRY, vol. 90, pp. 124-131, ISSN:1052-0295 DOI   Accesso ONLINE all'editore

  Buemi, Maria Rosa; De Luca, Laura; Ferro, Stefania; Bruno, Elvira; Ceruso, Mariangela; Supuran, Claudiu T.; Pospíšilová, Klára; Brynda, Jiří; Řezáčová, Pavlína; Gitto, Rosaria (2015). Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 102, pp. 223-232, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Mojzych, Mariusz; Ceruso, Mariangela; Bielawska, Anna; Bielawski, Krzysztof; Fornal, Emilia; Supuran, Claudiu T. (2015). New pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 3674-3680, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Alafeefy, Ahmed M; Abdel-Aziz, Hatem A.; Vullo, Daniela; Al-Tamimi, Abdul-Malek S.; Awaad, Amani S.; Mohamed, Menshawy A.; Capasso, Clemente; Supuran, Claudiu T. (2015). Inhibition of human carbonic anhydrase isozymes I, II, IX and XII with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 52-56, ISSN:1475-6366 DOI  

  Mahon, Brian P; Hendon, Alex M.; Driscoll, Jenna M.; Rankin, Gregory M.; Poulsen, Sally-Ann; Supuran, Claudiu T.; Mckenna, Robert (2015). Saccharin: A lead compound for structure-based drug design of carbonic anhydrase IX inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 849-854, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Ombouma, Joanna; Vullo, Daniela; Dumy, Pascal; Supuran, Claudiu T.; Winum, Jean-Yves (2015). Carbonic Anhydrase Glycoinhibitors belonging to the Aminoxysulfonamide Series. ACS MEDICINAL CHEMISTRY LETTERS, vol. 6, pp. 819-821, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  De Simone, Giuseppina; Di Fiore, Anna; Capasso, Clemente; Supuran, Claudiu T. (2015). The zinc coordination pattern in the η-carbonic anhydrase from Plasmodium falciparum is different from all other carbonic anhydrase genetic families. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 25, pp. 1385-1389, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Mojzych, Mariusz; Karczmarzyk, Zbigniew; Wysocki, Waldemar; Ceruso, Mariangela; Supuran, Claudiu T.; Kryštof, Vladimir; Urbańczyk-Lipkowska, Zofia; Kalicki, Przemysław (2015). New approaches to the synthesis of sildenafil analogues and their enzyme inhibitory activity. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 1421-1429, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  De Luca, Viviana; Vullo, Daniela; Del Prete, Sonia; Carginale, Vincenzo; Scozzafava, Andrea; Osman, Sameh M.; Alothman, Zeid; Supuran, Claudiu T.; Capasso, Clemente (2015). Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 4405-4409, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Khloya, Poonam; Ceruso, Mariangela; Ram, Sita; Supuran, Claudiu T.; Sharma, Pawan K. (2015). Sulfonamide bearing pyrazolylpyrazolines as potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 25, pp. 3208-3212, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Cvijetić, Ilija N; Tanç, Muhammet; Juranić, Ivan O.; Verbić, Tatjana Ž.; Supuran, Claudiu T.; Drakulić, Branko J. (2015). 5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 4649-4659, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Durgun, Mustafa; Turkmen, Hasan; Ceruso, Mariangela; Supuran, Claudiu T. (2015). Synthesis of Schiff base derivatives of 4-(2-aminoethyl)-benzenesulfonamide with inhibitory activity against carbonic anhydrase isoforms I, II, IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 25, pp. 2377-2381, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Akdemir, Atilla; De Monte, Celeste; Carradori, Simone; Supuran, Claudiu T. (2015). Computational investigation of the selectivity of salen and tetrahydrosalen compounds towards the tumor-associated hCA XII isozyme. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 114-118, ISSN:1475-6366 DOI  

  Supuran, Claudiu T* (2015). Acetazolamide for the treatment of idiopathic intracranial hypertension. EXPERT REVIEW OF NEUROTHERAPEUTICS, vol. 15, pp. 851-856, ISSN:1473-7175 DOI  

  Di Fiore, Anna; Vergara, Alessandro; Caterino, Marco; Alterio, Vincenzo; Monti, Simona M; Ombouma, Joanna; Dumy, Pascal; Vullo, Daniela; Supuran, Claudiu T; Winum, Jean-Yves; De Simone, Giuseppina (2015). Hydroxylamine-O-sulfonamide is a versatile lead compound for the development of carbonic anhydrase inhibitors. CHEMICAL COMMUNICATIONS, vol. 51, pp. 11519-22-11522, ISSN:1364-548X DOI  

  Akincioğlu, Akin; Akincioğlu, Hülya; Gülçin, Ilhami; Durdagi, Serdar; Supuran, Claudiu T.; Göksu, Süleyman (2015). Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: Novel sulfamoylcarbamates and sulfamides derived from acetophenones. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 3592-3602, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Syrjänen, Leo; Kuuslahti, Marianne; Tolvanen, Martti; Vullo, Daniela; Parkkila, Seppo; Supuran, Claudiu T. (2015). The β-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 2303-2309, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Grandane, Aiga; Tanc, Muhammet; Di Cesare Mannelli, Lorenzo; Carta, Fabrizio; Ghelardini, Carla; Žalubovskis, Raivis; Supuran, Claudiu T. (2015). 6-substituted sulfocoumarins are selective carbonic anhdydrase IX and XII Inhibitors with significant cytotoxicity against colorectal cancer cells. JOURNAL OF MEDICINAL CHEMISTRY, vol. 58, pp. 3975-3983, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Leitans, Janis; Kazaks, Andris; Balode, Agnese; Ivanova, Jekaterina; Zalubovskis, Raivis; Supuran, Claudiu T.; Tars, Kaspars (2015). Efficient Expression and Crystallization System of Cancer-Associated Carbonic Anhydrase Isoform IX. JOURNAL OF MEDICINAL CHEMISTRY, vol. 58, pp. 9004-9009, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Bragagni, Marco; Scozzafava, Andrea; Mastrolorenzo, Antonio; Supuran, Claudiu T.; Mura, Paola (2015). Development and ex vivo evaluation of 5-aminolevulinic acid-loaded niosomal formulations for topical photodynamic therapy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 494, pp. 258-263, ISSN:0378-5173

  Vullo, Daniela; Bhatt, Avni; Mahon, Brian P.; Mckenna, Robert; Supuran, Claudiu T (2015). Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 26, pp. 401-405, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Karioti, Anastasia; Ceruso, Mariangela; Carta, Fabrizio; Bilia, Anna-Rita; Supuran, Claudiu T (2015). New natural product carbonic anhydrase inhibitors incorporating phenol moieties. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 7219-25-7225, ISSN:0968-0896 DOI  

  Cincinelli, Alessandra; Martellini, Tania; Vullo, Daniela; Supuran, Claudiu T (2015). Anion and sulfonamide inhibition studies of an α-carbonic anhydrase from the Antarctic hemoglobinless fish Chionodraco hamatus. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 25, pp. 5485-9-5489, ISSN:0960-894X DOI  

  Maresca, Alfonso; Akyuz, Gulay; Osman, Sameh M; Alothman, Zeid; Supuran, Claudiu T (2015). Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 7181-8-7188, ISSN:0968-0896 DOI  

  Santamaria, Salvatore; Nuti, Elisa; Cercignani, Giovanni; La Regina, Giuseppe; Silvestri, Romano; Supuran, Claudiu T.; Rossello, Armando (2015). Kinetic characterization of 4,4′-biphenylsulfonamides as selective non-zinc binding MMP inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 947-954, ISSN:1475-6366 DOI  

  Yılmaz, Özgür; Özbaş Turan, Suna; Akbuğa, Jülide; Tiber, Pınar Mega; Orun, Oya; Supuran, Claudiu T.; Küçükgüzel, Ş. Güniz (2015). Synthesis of pro-apoptotic indapamide derivatives as anticancer agents. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 967-80-980, ISSN:1475-6366 DOI  

  Diaz, Jorge R A; Camí, Gerardo Enrique; Liu-González, Malva; Vega, Daniel R; Vullo, Daniela; Juárez, Américo; Pedregosa, José C; Supuran, Claudiu T (2015). Salts of 5-amino-2-sulfonamide-1,3,4-thiadiazole, a structural and analog of acetazolamide, show interesting carbonic anhydrase inhibitory properties, diuretic, and anticonvulsant action. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 1-9-9, ISSN:1475-6366 DOI  

  Işık, Semra; Vullo, Daniela; Durdagi, Serdar; Ekinci, Deniz; Şentürk, Murat; Çetin, Ahmet; Şentürk, Esra; Supuran, Claudiu T (2015). Interaction of carbonic anhydrase isozymes I, II, and IX with some pyridine and phenol hydrazinecarbothioamide derivatives. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 25, pp. 5636-41-5641, ISSN:0960-894X DOI  

  Reza Zolfaghari Emameh; Leo Syrjänen; Harlan Barkera; Claudiu T. Supuran; Seppo Parkkila (2015). Drosophila melanogaster: A model organism for controlling Dipteran vectors and pests. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 505-513, ISSN:1475-6366 DOI  

  Carta, Fabrizio; Osman, Sameh M.; Vullo, Daniela; Gullotto, Antonella; Winum, Jean-Yves; Alothman, Zeid; Masini, Emanuela; Supuran, Claudiu T. (2015). Poly(amidoamine) dendrimers with carbonic anhydrase inhibitory activity and antiglaucoma action. JOURNAL OF MEDICINAL CHEMISTRY, vol. 58, pp. 4039-4045, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Bozdag, Murat; Carta, Fabrizio; Vullo, Daniela; Akdemir, Atilla; Isik, Semra; Lanzi, Cecilia; Scozzafava, Andrea; Masini, Emanuela; Supuran, Claudiu T. (2015). Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 2368-2376, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Fulvio Ratto; Ewa Witort; Francesca Tatini; Sonia Centi; Lorenza Lazzeri; Fabrizio Carta; Matteo Lulli; Daniela Vullo; Franco Fusi; Claudiu T. Supuran; Andrea Scozzafava; Sergio Capaccioli; Roberto Pini (2015). Plasmonic Particles that Hit Hypoxic Cells. ADVANCED FUNCTIONAL MATERIALS, vol. 25, pp. 316-323, ISSN:1616-3028 DOI  

  Nocentini, Alessio; Carta, Fabrizio; Ceruso, Mariangela; Bartolucci, Gianluca; Supuran, Claudiu T. (2015). Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 6955-6966, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Dilworth, Jonathan R; Pascu, Sofia I.; Waghorn, Philip A.; Vullo, Daniela; Bayly, Simon R.; Christlieb, Martin; Sun, Xin; Supuran, Claudiu T. (2015). Synthesis of sulfonamide conjugates of Cu(ii), Ga(iii), In(iii), Re(v) and Zn(ii) complexes: Carbonic anhydrase inhibition studies and cellular imaging investigations. DALTON TRANSACTIONS, vol. 44, pp. 4859-4873, ISSN:1477-9226 DOI   Accesso ONLINE all'editore

  Supuran, Claudiu T; Winum, Jean-Yves (2015). Carbonic anhydrase IX inhibitors in cancer therapy: An update. FUTURE MEDICINAL CHEMISTRY, vol. 7, pp. 1407-1414, ISSN:1756-8919 DOI   Accesso ONLINE all'editore

  Ward, Carol; Meehan, James; Mullen, Peter; Supuran, Claudiu; Dixon, J Michael; Thomas, Jeremy S; Winum, Jean-Yves; Lambin, Philippe; Dubois, Ludwig; Pavathaneni, Nanda-Kumar; Jarman, Edward J; Renshaw, Lorna; Um, In Hwa; Kay, Charlene; Harrison, David J; Kunkler, Ian H; Langdon, Simon P (2015). Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models. ONCOTARGET, vol. 6, pp. 24856-70-24870, ISSN:1949-2553 DOI  

  Del Prete, Sonia; Vullo, Daniela; De Luca, Viviana; Alothman, Zeid; Osman, Sameh M.; Supuran, Claudiu T.; Capasso, Clemente (2015). Biochemical characterization of recombinant β-carbonic anhydrase (PgiCAb) identified in the genome of the oral pathogenic bacterium Porphyromonas gingivalis. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 366-370, ISSN:1475-6366 DOI  

  Abdel-Aziz, Alaa A.-M.; El-Azab, Adel S.; Ekinci, Deniz; Şentürk, Murat; Supuran, Claudiu T. (2015). Investigation of arenesulfonyl-2-imidazolidinones as potent carbonic anhydrase inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 81-84, ISSN:1475-6366 DOI  

  Vullo, Daniela; Del Prete, Sonia; Fisher, Gillian M.; Andrews, Katherine T.; Poulsen, Sally-Ann; Capasso, Clemente; Supuran, Claudiu T. (2015). Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 526-531, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Meleddu, Rita; Maccioni, Elias; Distinto, Simona; Bianco, Giulia; Melis, Claudia; Alcaro, Stefano; Cottiglia, Filippo; Ceruso, Mariangela; Supuran, Claudiu T. (2015). New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 25, pp. 3281-3284, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Yildirim, Alper; Atmaca, Ufuk; Keskin, Ali; Topal, Meryem; Çelik, Murat; Gülçin, Ilhami; Supuran, Claudiu T. (2015). N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes i and II. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 2598-2605, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Awadallah, Fadi M; El-Waei, Tamer A.; Hanna, Mona M.; Abbas, Safinaz E.; Ceruso, Mariangela; Oz, Beyza Ecem; Guler, Ozen Ozensoy; Supuran, Claudiu T. (2015). Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 96, pp. 425-435, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Carta, Fabrizio; Osman, Sameh M.; Vullo, Daniela; Alothman, Zeid; Del Prete, Sonia; Capasso, Clemente; Supuran, Claudiu T. (2015). Poly(amidoamine) dendrimers show carbonic anhydrase inhibitory activity against α-, β-, γ- and η-class enzymes. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 6794-6798, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Fidan, İsmail; Salmas, Ramin Ekhteiari; Arslan, Mehmet; Şentürk, Murat; Durdagi, Serdar; Ekinci, Deniz; Şentürk, Esra; Coşgun, Sedat; Supuran, Claudiu T (2015). Carbonic anhydrase inhibitors: Design, synthesis, kinetic, docking and molecular dynamics analysis of novel glycine and phenylalanine sulfonamide derivatives. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 7353-8-7358, ISSN:0968-0896 DOI  

  Ferraroni, Marta; Del Prete, Sonia; Vullo, Daniela; Capasso, Clemente; Supuran, Claudiu T. (2015). Crystal structure and kinetic studies of a tetrameric type II β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. ACTA CRYSTALLOGRAPHICA. SECTION D, BIOLOGICAL CRYSTALLOGRAPHY, vol. 71, pp. 2449-2456, ISSN:0907-4449 DOI   Accesso ONLINE all'editore

  D'Ambrosio, Katia; Carradori, Simone; Monti, Simona M; Buonanno, Martina; Secci, Daniela; Vullo, Daniela; Supuran, Claudiu T; De Simone, Giuseppina (2015). Out of the active site binding pocket for carbonic anhydrase inhibitors. CHEMICAL COMMUNICATIONS, vol. 51, pp. 302-305, ISSN:1364-548X DOI  

  Alterio, V; Tanc, M.; Ivanova, J.; Zalubovskis, R.; Vozny, I.; Monti, S.M.; Di Fiore, A.; De Simone, G.; Supuran, C.T. (2015). X-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 13, pp. 4064-4069, ISSN:1477-0520 DOI   Accesso ONLINE all'editore

  Zolfaghari Emameh, Reza; Kuuslahti, Marianne; Vullo, Daniela; Barker, Harlan R.; Supuran, Claudiu T.; Parkkila, Seppo (2015). Ascaris lumbricoides β carbonic anhydrase: A potential target enzyme for treatment of ascariasis. PARASITES & VECTORS, vol. 8, pp. 479-489, ISSN:1756-3305 DOI   Accesso ONLINE all'editore

  Dedeoglu, Nurcan; De Luca, Viviana; Isik, Semra; Yildirim, Hatice; Kockar, Feray; Capasso, Clemente; Supuran, Claudiu T. (2015). Cloning, characterization and anion inhibition study of a β-class carbonic anhydrase from the caries producing pathogen Streptococcus mutans. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 2995-3001, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  De Luca, Viviana; Del Prete, Sonia; Carginale, Vincenzo; Vullo, Daniela; Supuran, Claudiu T.; Capasso, Clemente (2015). Cloning, characterization and anion inhibition studies of a γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 25, pp. 4970-4975, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Boztaş, Murat; Çetinkaya, Yasin; Topal, Meryem; Gülçin, Ilhami; Menzek, Abdullah; Şahin, Ertan; Tanc, Muhammet; Supuran, Claudiu T. (2015). Synthesis and carbonic anhydrase isoenzymes I, II, IX, and XII inhibitory effects of dimethoxybromophenol derivatives incorporating cyclopropane moieties. JOURNAL OF MEDICINAL CHEMISTRY, vol. 58, pp. 640-650, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Carta, Fabrizio; Di Cesare Mannelli, Lorenzo; Pinard, Melissa; Ghelardini, Carla; Scozzafava, Andrea; Mckenna, Robert; Supuran, Claudiu T. (2015). A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 1828-1840, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Bozdag, Murat; Alafeefy, Ahmed M.; Vullo, Daniela; Carta, Fabrizio; Dedeoglu, Nurcan; Al-Tamimi, Abdul-Malek S.; Al-Jaber, Nabila A.; Scozzafava, Andrea; Supuran, Claudiu T (2015). Benzenesulfonamides incorporating bulky aromatic/heterocyclic tails with potent carbonic anhydrase inhibitory activity. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 7751-7764, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Krasavin, Mikhail; Korsakov, Mikhail; Dorogov, Mikhail; Tuccinardi, Tiziano; Dedeoglu, Nurcan; Supuran, Claudiu T. (2015). Probing the 'bipolar' nature of the carbonic anhydrase active site: Aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 101, pp. 334-347, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Carre, Grégoire; Ouedraogo, Maurice; Magaud, Christophe; Carreyre, Hélène; Becq, Frédéric; Bois, Patrick; Supuran, Claudiu T.; Thibaudeau, Sébastien; Vandebrouck, Clarisse; Bescond, Jocelyn (2015). Vasorelaxation induced by dodoneine is mediated by calcium channels blockade and carbonic anhydrase inhibition on vascular smooth muscle cells. JOURNAL OF ETHNOPHARMACOLOGY, vol. 169, pp. 8-17, ISSN:0378-8741 DOI   Accesso ONLINE all'editore

  Perut, Francesca; Carta, Fabrizio; Bonuccelli, Gloria; Grisendi, Giulia; Di Pompo, Gemma; Avnet, Sofia; Sbrana, Francesca Vittoria; Hosogi, Shigekuni; Dominici, Massimo; Kusuzaki, Katsuyuki; Supuran, Claudiu T; Baldini, Nicola (2015). Carbonic anhydrase IX inhibition is an effective strategy for osteosarcoma treatment. EXPERT OPINION ON THERAPEUTIC TARGETS, pp. 1-13, ISSN:1472-8222 DOI  

  Ceruso, Mariangela; Carta, Fabrizio; Osman, Sameh M.; Alothman, Zeid; Monti, Simona Maria; Supuran, Claudiu T. (2015). Inhibition studies of bacterial, fungal and protozoan β-class carbonic anhydrases with Schiff bases incorporating sulfonamide moieties. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 4181-4187, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Mahon, Brian P; Lomelino, Carrie L.; Ladwig, Janina; Rankin, Gregory M.; Driscoll, Jenna M.; Salguero, Antonieta L.; Pinard, Melissa A.; Vullo, Daniela; Supuran, Claudiu T.; Poulsen, Sally-Ann; Mckenna, Robert (2015). Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates. JOURNAL OF MEDICINAL CHEMISTRY, vol. 58, pp. 6630-6638, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Grandane, Aiga; Tanc, Muhammet; Žalubovskis, Raivis; Supuran, Claudiu T. (2015). Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 1430-1436, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Gidaro, Maria Concetta; Alcaro, Francesca; Carradori, Simone; Costa, Giosuè; Vullo, Daniela; Supuran, Claudiu T.; Alcaro, Stefano (2015). Eriocitrin and apigenin as new carbonic anhydrase VA inhibitors from a virtual screening of calabrian natural products. PLANTA MEDICA, vol. 81, pp. 533-540, ISSN:0032-0943 DOI   Accesso ONLINE all'editore

  Ibrahim, Diaa A.; Lasheen, Deena S.; Zaky, Maysoun Y.; Ibrahim, Amany W.; Vullo, Daniela; Ceruso, Mariangela; Supuran, Claudiu T.; Abou El Ella, Dalal A. (2015). Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 4989-4999, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Sahin, Aysegul; Isik, Semra; Arslan, Oktay; Supuran, Claudiu T.; Ozensoy Guler, Ozen (2015). A new affinity gel for the purification of α-carbonic anhdrases. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 224-228, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Vullo, Daniela; De Luca, Viviana; Del Prete, Sonia; Carginale, Vincenzo; Scozzafava, Andrea; Capasso, Clemente; Supuran, Claudiu T. (2015). Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 25, pp. 3550-3555, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Winum, Jean-Yves; Supuran, Claudiu T. (2015). Recent advances in the discovery of zinc-binding motifs for the development of carbonic anhydrase inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 321-324, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Korkmaz, Neslihan; Obaidi, Oday A.; Senturk, Murat; Astley, Demet; Ekinci, Deniz; Supuran, Claudiu T. (2015). Synthesis and biological activity of novel thiourea derivatives as carbonic anhydrase inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 75-80, ISSN:1475-6366 DOI  

  Le Darz, Alexandre; Mingot, Agnès; Bouazza, Fodil; Castelli, Ugo; Karam, Omar; Tanc, Muhammet; Supuran, Claudiu T.; Thibaudeau, Sébastien (2015). Fluorinated pyrrolidines and piperidines incorporating tertiary benzenesulfonamide moieties are selective carbonic anhydrase II inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 737-745, ISSN:1475-6366 DOI  

  Del Prete, Sonia; Vullo, Daniela; Osman, Sameh M.; Alothman, Zeid; Capasso, Clemente; Supuran, Claudiu T. (2015). Anion inhibition studies of the dandruff-producing fungus Malassezia globosa β-carbonic anhydrase MgCA. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 25, pp. 5194-5198, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  La Regina, Giuseppe; Coluccia, Antonio; Famiglini, Valeria; Pelliccia, Sveva; Monti, Ludovica; Vullo, Daniela; Nuti, Elisa; Alterio, Vincenzo; De Simone, Giuseppina; Monti, Simona Maria; Pan, Peiwen; Parkkila, Seppo; Supuran, Claudiu T.; Rossello, Armando; Silvestri, Romano (2015). Discovery of 1,1′-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors. JOURNAL OF MEDICINAL CHEMISTRY, vol. 58, pp. 8564-8572, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Bragagni, Marco; Bozdag, Murat; Carta, Fabrizio; Scozzafava, Andrea; Lanzi, Cecilia; Masini, Emanuela; Mura, Paola; Supuran, Claudiu T. (2015). Cyclodextrin complexation highly enhances efficacy of arylsulfonylureido benzenesulfonamide carbonic anhydrase inhibitors as a topical antiglaucoma agents. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 6223-6227, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  Di Cesare Mannelli, Lorenzo; Micheli, Laura; Carta, Fabrizio; Cozzi, Andrea; Ghelardini, Carla; Supuran, Claudiu T (2015). Carbonic anhydrase inhibition for the management of cerebral ischemia: in vivo evaluation of sulfonamide and coumarin inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 1-6, ISSN:1475-6366 DOI  

  Singasane, Namrata; Kharkar, Prashant S.; Ceruso, Mariangela; Supuran, Claudiu T.; Toraskar, Mrunmayee P. (2015). Inhibition of carbonic anhydrase isoforms I, II, IX and XII with Schiff’s bases incorporating iminoureido moieties. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 901-7-907, ISSN:1475-6366 DOI  

  Squarcialupi, L.; Falsini, M.; Catarzi, D.; Varano, F.; Betti, M.; Di Cesare Mannelli, L.; Zanardelli, M.; Ghelardini, C.; Tanc, M.; Supuran, C.T.; Colotta, V. (2015). 3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new potent and selective inhibitors of the tumor-associated carbonic anhydrase IX and XII.. In: XXIII National Meeting on Medicinal Chemistry, 6-9 settembre 2015, Salerno., d, pp. 131-131.

  Trabocchi, Andrea; Pala, N.; Krimmelbein, I.; Menchi, Gloria; Guarna, Antonio; Sechi, M.; Dreker, T.; Scozzafava, Andrea; Supuran, CLAUDIU TRANDAFIR; Carta, Fabrizio (2015). Peptidomimetics as protein arginine deiminase 4 (PAD4) inhibitors.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 466-471, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Alafeefy, Ahmed M.*; Abdel-Aziz, Hatem A.; Carta, F.; Supuran, Claudiu T.; Pathak, Shilendra K.; Prasad, Onkar; Sinha, Leena (2015). Exploring QSARs of some benzenesulfonamides incorporating cyanoacrylamide moieties as a carbonic anhydrase inhibitors (specifically against tumor-associated isoforms IX and XII). JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 519-523, ISSN:1475-6366 DOI  

  Strom, T Amanda; Durdagi, Serdar; Ersoz, Suha Salih; Salmas, Ramin Ekhteiari; Supuran, Claudiu T; Barron, Andrew R (2015). Fullerene-based inhibitors of HIV-1 protease. JOURNAL OF PEPTIDE SCIENCE, vol. 21, pp. 862-70-870, ISSN:1075-2617 DOI  

  Vullo, Daniela*; Isik, Semra; Bozdag, Murat; Carta, Fabrizio; Supuran, Claudiu T. (2015). 7-Amino-3,4-dihydro-1H-quinolin-2-one, a compound similar to the substituted coumarins, inhibits α-carbonic anhydrases without hydrolysis of the lactam ring.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 773-777, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Carradori, Simone; Mollica, Adriano; Ceruso, Mariangela; D'Ascenzio, Melissa; De Monte, Celeste; Chimenti, Paola; Sabia, Rocchina; Akdemir, Atilla; Supuran, Claudiu T. (2015). New amide derivatives of Probenecid as selective inhibitors of carbonic anhydrase IX and XII: Biological evaluation and molecular modelling studies. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 2975-2981, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Mollica, Adriano; Costante, Roberto; Akdemir, Atilla; Carradori, Simone; Stefanucci, Azzurra; Macedonio, Giorgia; Ceruso, Mariangela; Supuran, Claudiu T. (2015). Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 5311-8-5318, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  De Luca, Viviana; Del Prete, Sonia; Supuran, Claudiu T.; Capasso, Clemente (2015). Protonography, a new technique for the analysis of carbonic anhydrase activity. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 277-282, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Pinard, Melissa A; Lotlikar, Shalaka R.; Boone, Christopher D.; Vullo, Daniela; Supuran, Claudiu T.; Patrauchan, Marianna A.; Mckenna, Robert (2015). Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, pp. 4831-4838, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Göcer, Hülya; Akincioʇlu, Akin; Göksu, Süleyman; Gülçin, Ilhami; Supuran, Claudiu T. (2015). Carbonic anhydrase and acetylcholinesterase inhibitory effects of carbamates and sulfamoylcarbamates. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 316-320, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Alafeefy AM; Ceruso M; Al-Jaber NA; Parkkila S; Vermelho AB; Supuran CT (2015). A new class of quinazoline-sulfonamides acting as efficient inhibitors against the α-carbonic anhydrase from Trypanosoma cruzi. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 581-585, ISSN:1475-6366 DOI  

  José, O.; Torres-Rodríguez, P.; Forero-Quintero, L.S.; Chávez, J.C.; De La Vega-Beltrán, J.L.; Carta, F.; Supuran, C.T.; Deitmer, J.W.; Treviño, C.L.* (2015). Carbonic anhydrases and their functional differences in human and mouse sperm physiology. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 468, pp. 713-718, ISSN:0006-291X DOI   Accesso ONLINE all'editore

  Del Prete, Sonia; De Luca, Viviana; Supuran, Claudiu T; Capasso, Clemente (2015). Protonography, a technique applicable for the analysis of η-carbonic anhydrase activity. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 920-4-924, ISSN:1475-6366 DOI  

  Dekaminaviciute, Dovile; Kairys, Visvaldas; Zilnyte, Milda; Petrikaite, Vilma; Jogaite, Vaida; Matuliene, Jurgita; Gudleviciene, Zivile; Vullo, Daniela; Supuran, Claudiu T.; Zvirbliene, Aurelija (2014). Monoclonal antibodies raised against 167-180 aa sequence of human carbonic anhydrase XII inhibit its enzymatic activity. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 29, pp. 804-810, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Ghorab, Mostafa M.; Ceruso, Mariangela; Alsaid, Mansour S.; Nissan, Yassin M.; Arafa, Reem K.; Supuran, Claudiu T. (2014). Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: Synthesis, cytotoxic activity and molecular modeling. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 87, pp. 186-196, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Meijer, Tineke W. H; Bussink, Johan; Zatovicova, Miriam; Span, Paul N.; Lok, Jasper; Supuran, Claudiu T.; Kaanders, Johannes H. A. M. (2014). Tumor microenvironmental changes induced by the sulfamate carbonic anhydrase IX inhibitor S4 in a laryngeal tumor model. PLOS ONE, vol. 9, pp. 1-8, ISSN:1932-6203 DOI   Accesso ONLINE all'editore

  Del Prete, Sonia; Vullo, Daniela; De Luca, Viviana; Supuran, Claudiu T.; Capasso, Clemente (2014). Biochemical characterization of the δ-carbonic anhydrase from the marine diatom Thalassiosira weissflogii, TweCA. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 29, pp. 906-911, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  De Luca, Laura; Ferro, Stefania; Damiano, Francesca M.; Supuran, Claudiu T.; Vullo, Daniela; Chimirri, Alba; Gitto, Rosaria (2014). Structure-based screening for the discovery of new carbonic anhydrase VII inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 71, pp. 105-111, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Moeker, Janina; Peat, Thomas S.; Bornaghi, Laurent F.; Vullo, Daniela; Supuran, Claudiu T; Poulsen, Sally-Ann (2014). Cyclic secondary sulfonamides: Unusually good inhibitors of cancer-related carbonic anhydrase enzymes. JOURNAL OF MEDICINAL CHEMISTRY, vol. 57, pp. 3522-3531, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Saluja, Amrita K.; Tiwari, Meena; Vullo, Daniela; Supuran, Claudiu T. (2014). Substituted benzene sulfonamides incorporating 1,3,5-triazinyl moieties potently inhibit human carbonic anhydrases II, IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 1310-1314, ISSN:0960-894X DOI  

  Khloya, Poonam; Celik, Gulsah; Sitaram, Null; Vullo, Daniela; Supuran, Claudiu T.; Sharma, Pawan K (2014). 4-Functionalized 1,3-diarylpyrazoles bearing benzenesulfonamide moiety as selective potent inhibitors of the tumor associated carbonic anhydrase isoforms IX and XII. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 76, pp. 284-290, ISSN:0223-5234 DOI  

  Sitaram, Null; Celik, Gulsah; Khloya, Poonam; Vullo, Daniela; Supuran, Claudiu T.; Sharma, Pawan K. (2014). Benzenesulfonamide bearing 1,2,4-triazole scaffolds as potent inhibitors of tumor associated carbonic anhydrase isoforms hCA IX and hCA XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 1873-1882, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Mercan, Levent; Ekinci, Deniz; Supuran, Claudiu T. (2014). Characterization of carbonic anhydrase from Turkish native "gerze" chicken and influences of metal ions on enzyme activity. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 29, pp. 773-776, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  D'Ascenzio, Melissa; Carradori, Simone; Secci, Daniela; Vullo, Daniela; Ceruso, Mariangela; Akdemir, Atilla; Supuran, Claudiu T. (2014). Selective inhibition of human carbonic anhydrases by novel amide derivatives of probenecid: Synthesis, biological evaluation and molecular modelling studies. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 3982-3988, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  De Monte, Celeste; Carradori, Simone; Secci, Daniela; D'Ascenzio, Melissa; Vullo, Daniela; Ceruso, Mariangela; Supuran, Claudiu T. (2014). Cyclic tertiary sulfamates: Selective inhibition of the tumor-associated carbonic anhydrases IX and XII by N- and O-substituted acesulfame derivatives. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 84, pp. 240-246, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Rosatelli, Emiliano; Carotti, Andrea; Ceruso, Mariangela; Supuran, Claudiu T.; Gioiello, Antimo (2014). Flow synthesis and biological activity of aryl sulfonamides as selective carbonic anhydrase IX and XII inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 3422-3425, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Congiu, Cenzo; Onnis, Valentina; Balboni, Gianfranco; Supuran, Claudiu T. (2014). Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1- enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 1776-1779, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Krall, Nikolaus; Pretto, Francesca; Decurtins, Willy; Bernardes, Gonçalo J. L.; Supuran, Claudiu T.; Neri, Dario (2014). A small-molecule drug conjugate for the treatment of carbonic anhydrase IX expressing tumors. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 53, pp. 4231-4235, ISSN:1433-7851 DOI   Accesso ONLINE all'editore

  Sethi, Kalyan K; Verma, Saurabh M.; Tanç, Muhammet; Purper, Gaultier; Calafato, Gaetan; Carta, Fabrizio; Supuran, Claudiu T. (2014). Carbonic anhydrase inhibitors: Synthesis and inhibition of the human carbonic anhydrase isoforms I, II, IX and XII with benzene sulfonamides incorporating 4- and 3-nitrophthalimide moieties. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 1586-1595, ISSN:0968-0896 DOI  

  Lehneck, Ronny; Neumann, Piotr; Vullo, Daniela; Elleuche, Skander; Supuran, Claudiu T.; Ficner, Ralf; Pöggeler, Stefanie (2014). Crystal structures of two tetrameric β-carbonic anhydrases from the filamentous ascomycete Sordaria macrospora. THE FEBS JOURNAL, vol. 281, pp. 1759-1772, ISSN:1742-464X DOI  

  M. Saada;D. Vullo;J. Montero;A. Scozzafava;C. T. Supuran;J. Winum (2014). Mono- and di-halogenated histamine, histidine and carnosine derivatives are potent carbonic anhydrase I, II, VII, XII and XIV activators.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 4752-4758, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  D. Vullo;M. Milos;B. Galic;A. Scozzafava;C. T. Supuran (2014). Dipotassium-trioxohydroxytetrafluorotriborate, K2[B3O3F4OH], is a potent inhibitor of human carbonic anhydrases.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 1-4, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  I. Nishimori;D. Vullo;T. Minakuchi;A. Scozzafava;C. Capasso;C. T. Supuran (2014). Sulfonamide inhibition studies of two β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 2939-2946, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  A. Scozzafava;C. T. Supuran (2014). Glaucoma and the applications of carbonic anhydrase inhibitors.. In: Supuran C.. Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications, pp. 349-359 SPRINGER, 233 SPRING ST, NEW YORK, NY 10013 USA. DOI   Accesso ONLINE all'editore

  Ombouma, Joanna; Vullo, Daniela; Supuran, Claudiu T.; Winum, Jean-Yves (2014). Ferrier sulfamidoglycosylation of glycals catalyzed by nitrosonium tetrafluoroborate: Towards new carbonic anhydrase glycoinhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 6353-6359, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Akbaba, Yusuf; Akincioǧlu, Akin; Göçer, Hülya; Göksu, Süleyman; Gülçin, Ilhami; Supuran, Claudiu T. (2014). Carbonic anhydrase inhibitory properties of novel sulfonamide derivatives of aminoindanes and aminotetralins. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 29, pp. 35-42, ISSN:1475-6366 DOI  

  Carta, Fabrizio*; Bozdag, Murat; Tanc, Muhammet; Supuran, Claudiu (2014). Next-generation dithiocarbamate carbonic anhydrase inhibitors. In: Claudiu T Supuran e Clemente Capasso (editors). Targeting Carbonic Anhydrases, pp. 114-130 Future Medicine Ltd., ISBN:978-190945391-3. DOI   Accesso ONLINE all'editore

  Abdel-Aziz, Alaa A.-M.; El-Azab, Adel S.; Ceruso, Mariangela; Supuran, Claudiu T. (2014). Carbonic anhydrase inhibitory activity of sulfonamides and carboxylic acids incorporating cyclic imide scaffolds. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 5185-5189, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Sławiński, Jarosław; Brzozowski, Zdzisław; Zołnowska, Beata; Szafrański, Krzysztof; Pogorzelska, Aneta; Vullo, Daniela; Supuran, Claudiu T. (2014). Synthesis of a new series of N4-substituted 4-(2-aminoethyl) benzenesulfonamides and their inhibitory effect on human carbonic anhydrase cytosolic isozymes i and II and transmembrane tumor-associated isozymes IX and XII. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 84, pp. 59-67, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Tauro, Marilena; Loiodice, Fulvio; Ceruso, Mariangela; Supuran, Claudiu T.; Tortorella, Paolo (2014). Arylamino bisphosphonates: Potent and selective inhibitors of the tumor-associated carbonic anhydrase XII. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 1941-1943, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Sarikaya, Busra; Ceruso, Mariangela; Carta, Fabrizio; Supuran, Claudiu T. (2014). Inhibition of carbonic anhydrase isoforms I, II, IX and XII with novel Schiff bases: Identification of selective inhibitors for the tumor-associated isoforms over the cytosolic ones. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 5883-5890, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Abdelrahim, M. Yahia M.; Tanc, Muhammet; Winum, Jean-Yves; Supuran, Claudiu T; Barboiu, Mihail (2014). Dominant behaviours in the expression of human carbonic anhydrase hCA i activity. CHEMICAL COMMUNICATIONS, vol. 50, pp. 8043-8046, ISSN:1359-7345 DOI   Accesso ONLINE all'editore

  Rodrigues, Giseli Capaci; Feijó, Daniel Ferreira; Bozza, Marcelo Torres; Pan, Peiwen; Vullo, Daniela; Parkkila, Seppo; Supuran, Claudiu T.; Capasso, Clemente; Aguiar, Alcino Palermo; Vermelho, Alane Beatriz (2014). Design, synthesis, and evaluation of hydroxamic acid derivatives as promising agents for the management of Chagas disease. JOURNAL OF MEDICINAL CHEMISTRY, vol. 57, pp. 298-308, ISSN:0022-2623 DOI  

  Moeker, Janina; Mahon, Brian P.; Bornaghi, Laurent F.; Vullo, Daniela; Supuran, Claudiu T.; Mckenna, Robert; Poulsen, Sally-Ann (2014). Structural insights into carbonic anhydrase IX isoform specificity of carbohydrate-based sulfamates. JOURNAL OF MEDICINAL CHEMISTRY, vol. 57, pp. 8635-8645, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  S. D. Prete;D. Vullo;A. Scozzafava;C. Capasso;C. T. Supuran (2014). Cloning, characterization and anion inhibition study of the δ-class carbonic anhydrase (TweCA) from the marine diatom Thalassiosira weissflogii.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 531-537, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Alafeefy, Ahmed M; Ceruso, Mariangela; Al-Tamimi, Abdul-Malek S.; Del Prete, Sonia; Capasso, Clemente; Supuran, Claudiu T. (2014). Quinazoline-sulfonamides with potent inhibitory activity against the α-carbonic anhydrase from Vibrio cholerae. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 5133-5140, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Tauro, Marilena; Loiodice, Fulvio; Ceruso, Mariangela; Supuran, Claudiu T.; Tortorella, Paolo (2014). Dual carbonic anhydrase/matrix metalloproteinase inhibitors incorporating bisphosphonic acid moieties targeting bone tumors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 2617-2620, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Draghici, Bogdan; Vullo, Daniela; Akocak, Suleyman; Walker, Ellen A.; Supuran, Claudiu T; Ilies, Marc A. (2014). Ethylene bis-imidazoles are highly potent and selective activators for isozymes VA and VII of carbonic anhydrase, with a potential nootropic effect. CHEMICAL COMMUNICATIONS, vol. 50, pp. 5980-5983, ISSN:1359-7345 DOI   Accesso ONLINE all'editore

  Mojzych, Mariusz; Bielawska, Anna; Bielawski, Krzysztof; Ceruso, Mariangela; Supuran, Claudiu T. (2014). Pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors with antitumor activity. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 2643-2647, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Alafeefy, Ahmed M.; Ceruso, Mariangela; Al-Tamimi, Abdul-Malek S; Del Prete, Sonia; Supuran, Claudiu T.; Capasso, Clemente (2014). Inhibition studies of quinazoline-sulfonamide derivatives against the γ-CA (PgiCA) from the pathogenic bacterium, Porphyromonas gingivalis. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 30, pp. 592-596, ISSN:1475-6366 DOI  

  O. Koz;D. Ekinci;A. Perrone;S. Piacente;O. Alankuş-Çalışkan;E. Bedir;C. T. Supuran (2014). Analysis of saponins and phenolic compounds as inhibitors of α-carbonic anhydrase isoenzymes.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 28, pp. 412-417, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Sławiński, Jarosław; Pogorzelska, Aneta; Zołnowska, Beata; Brozewicz, Kamil; Vullo, Daniela; Supuran, Claudiu T. (2014). Carbonic anhydrase inhibitors. Synthesis of a novel series of 5-substituted 2,4-dichlorobenzenesulfonamides and their inhibition of human cytosolic isozymes i and II and the transmembrane tumor-associated isozymes IX and XII. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 82, pp. 47-55, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Riafrecha, Leonardo E.; Rodríguez, Oscar M.; Vullo, Daniela; Supuran, Claudiu T.; Colinas, Pedro A. (2014). Attachment of carbohydrates to methoxyaryl moieties leads to highly selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 5308-5314, ISSN:0968-0896 DOI  

  Alafeefy, Ahmed M; Abdel-Aziz, Hatem A.; Vullo, Daniela; Al-Tamimi, Abdul-Malek S.; Al-Jaber, Nabila A.; Capasso, Clemente; Supuran, Claudiu T. (2014). Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfurihydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1, 3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 141-147, ISSN:0968-0896 DOI  

  Grandane, Aiga; Tanc, Muhammet; Zalubovskis, Raivis; Supuran, Claudiu T. (2014). Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 1522-1528, ISSN:0968-0896 DOI  

  M. Bozdag;M. Ferraroni;E. Nuti;D. Vullo;A. Rossello;F. Carta;A. Scozzafava;C. T. Supuran (2014). Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 334-340, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Capasso, Clemente; Supuran, Claudiu T. (2014). Sulfa and trimethoprim-like drugs-antimetabolites acting as carbonic anhydrase, dihydropteroate synthase and dihydrofolate reductase inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 29, pp. 379-387, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  D. Vullo;E. V. Kupriyanova;A. Scozzafava;C. Capasso;C. T. Supuran (2014). Anion inhibition study of the β-carbonic anhydrase (CahB1) from the cyanobacterium Coleofasciculus chthonoplastes (ex-Microcoleus chthonoplastes).. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 1667-1671, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  L. Syrjänen;S. Parkkila;A. Scozzafava;C. T. Supuran (2014). Sulfonamide inhibition studies of the β carbonic anhydrase from Drosophila melanogaster.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 2797-2801, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Durdagi, Serdar; Scozzafava, Gabriele; Vullo, Daniela; Sahin, Hüseyin; Kolayli, Sevgi; Supuran, Claudiu T. (2014). Inhibition of mammalian carbonic anhydrases I-XIV with grayanotoxin III: Solution and in silico studies. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 29, pp. 469-475, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Pan, Jinhe; Lau, Joseph; Mesak, Felix; Hundal, Navjit; Pourghiasian, Maral; Liu, Zhibo; Bénard, François; Dedhar, Shoukat; Supuran, Claudiu T.; Lin, Kuo-Shyan (2014). Synthesis and evaluation of 18F-labeled carbonic anhydrase IX inhibitors for imaging with positron emission tomography. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 29, pp. 249-255, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  M. Bozdag;M. Pinard;F. Carta;E. Masini;A. Scozzafava;R. McKenna;C. T. Supuran (2014). A class of 4-Sulfamoylphenyl-ω-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 57, pp. 9673-9686, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  K. Chegaev;L. Lazzarato;Y. Tamboli;D. Boschi;M. Blangetti;A. Scozzafava;F. Carta;E. Masini;R. Fruttero;C. T. Supuran;A. Gasco (2014). Furazan and furoxan sulfonamides are strong α-carbonic anhydrase inhibitors and potential antiglaucoma agents.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 3913-3921, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Pala, Nicolino; Micheletto, Laura; Sechi, Mario; Aggarwal, Mayank; Carta, Fabrizio; Mckenna, Robert; Supuran, Claudiu T. (2014). Carbonic anhydrase inhibition with benzenesulfonamides and tetrafluorobenzenesulfonamides obtained via click chemistry. ACS MEDICINAL CHEMISTRY LETTERS, vol. 5, pp. 927-930, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Nasr, Gihane; Cristian, Alina; Barboiu, Mihail; Vullo, Daniela; Winum, Jean-Yves; Supuran, Claudiu T. (2014). Carbonic anhydrase inhibitors. Inhibition of human cytosolic isoforms i and II with (reduced) Schiff's bases incorporating sulfonamide, carboxylate and carboxymethyl moieties. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 2867-2874, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Alterio, Vincenzo; Pan, Peiwen; Parkkila, Seppo; Buonanno, Martina; Supuran, Claudiu T.; Monti, Simona M.; De Simone, Giuseppina (2014). The structural comparison between membrane-associated human carbonic anhydrases provides insights into drug design of selective inhibitors. BIOPOLYMERS, vol. 101, pp. 769-778, ISSN:0006-3525 DOI   Accesso ONLINE all'editore

  Ceruso, Mariangela; Del Prete, Sonia; Alothman, Zeid; Capasso, Clemente; Supuran, Claudiu T. (2014). Sulfonamides with potent inhibitory action and selectivity against the α-carbonic anhydrase from Vibrio cholerae. ACS MEDICINAL CHEMISTRY LETTERS, vol. 5, pp. 826-830, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  Akurathi, Vamsidhar; Dubois, Ludwig; Celen, Sofie; Lieuwes, Natasja G.; Chitneni, Satish K.; Cleynhens, Bernard J.; Innocenti, Alessio; Supuran, Claudiu T.; Verbruggen, Alfons M.; Lambin, Philippe; Bormans, Guy M (2014). Development and biological evaluation of 99mTc-sulfonamide derivatives for in vivo visualization of CA IX as surrogate tumor hypoxia markers. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 71, pp. 374-384, ISSN:0223-5234 DOI  

  Güney, Murat; Coşkun, Ahmet; Topal, Fevzi; Daştan, Arif; Gülçin, Ilhami; Supuran, Claudiu T. (2014). Oxidation of cyanobenzocycloheptatrienes: Synthesis, photooxygenation reaction and carbonic anhydrase isoenzymes inhibition properties of some new benzotropone derivatives. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 3537-3543, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Grandane, Aiga; Tanc, Muhammet; Zalubovskis, Raivis; Supuran, Claudiu T. (2014). 6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 1256-1260, ISSN:0960-894X DOI  

  Del Prete, Sonia; Vullo, Daniela; Fisher, Gillian M; Andrews, Katherine T; Poulsen, Sally-Ann; Capasso, Clemente; Supuran, Claudiu T (2014). Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum--the η-carbonic anhydrases. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 4389-4396, ISSN:1464-3405 DOI  

  I. Nishimori;D. Vullo;T. Minakuchi;A. Scozzafava;S. M. Osman;Z. Alothman;C. Capasso;C. T. Supuran (2014). Anion inhibition studies of two new β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 1127-1132, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Migliardini, Fortunato; De Luca, Viviana; Carginale, Vincenzo; Rossi, Mosè; Corbo, Pasquale; Supuran, Claudiu T.; Capasso, Clemente (2014). Biomimetic CO2 capture using a highly thermostable bacterial α-carbonic anhydrase immobilized on a polyurethane foam. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 29, pp. 146-150, ISSN:1475-6366 DOI  

  Pérez-Sayáns, Mario; Suárez-Peñaranda, J.M.; Torres-López, M.; Supuran, C.T.; Gándara-Vila, P.; Gayoso-Diz, P.; Barros-Angueira, F.; Blanco-Carrión, A.; Gándara-Rey, J.M.; García-García, A. (2014). Expression of CA IX in dysplasia adjacent to surgical resection margins of oral squamous cell carcinoma. BIOTECHNIC & HISTOCHEMISTRY, vol. 89, pp. 91-97, ISSN:1052-0295 DOI  

  Sitaram, Null; Ceruso, Mariangela; Khloya, Poonam; Supuran, Claudiu T.; Sharma, Pawan K. (2014). 4-Functionalized 1,3-diarylpyrazoles bearing 6-aminosulfonylbenzothiazole moiety as potent inhibitors of carbonic anhydrase isoforms hCA I, II, IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 6945-6952, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  D. Vullo;S. D. Prete;S. M. Osman;A. Scozzafava;Z. Alothman;C. T. Supuran;C. Capasso (2014). Anion inhibition study of the β-class carbonic anhydrase (PgiCAb) from the oral pathogen Porphyromonas gingivalis.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 4402-4406, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  S. D. Prete;D. Vullo;S. M. Osman;A. Scozzafava;Z. AlOthman;C. Capasso;C. T. Supuran (2014). Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: The β-class (PgiCAb) versus the γ-class (PgiCA) enzymes.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 4537-4543, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  M. Ceruso;S. D. Prete;Z. AlOthman;S. M. Osman;A. Scozzafava;C. Capasso;C. T. Supuran (2014). Synthesis of sulfonamides with effective inhibitory action against Porphyromonas gingivalis γ-carbonic anhydrase.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 4006-4010, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  D. Vullo;E. Flemetakis;A. Scozzafava;C. Capasso;C. T. Supuran (2014). Anion inhibition studies of two α-carbonic anhydrases from Lotus japonicus, LjCAA1 and LjCAA2.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 136, pp. 67-72, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  D. Vullo;S. D. Prete;S. M. Osman;V. D. Luca;A. Scozzafava;Z. Alothman;C. T. Supuran;C. Capasso (2014). Sulfonamide inhibition studies of the δ-carbonic anhydrase from the diatom Thalassiosira weissflogii.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 275-279, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  D. Vullo;S. D. Prete;S. M. Osman;V. D. Luca;A. Scozzafava;Z. Alothman;C. T. Supuran;C. Capasso (2014). Sulfonamide inhibition studies of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, pp. 240-244, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Sharma, Aditi; Tiwari, Meena; Supuran, Claudiu T (2014). Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IX. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 29, pp. 292-296, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  F. Carta;C. T. Supuran;A. Scozzafava (2014). Sulfonamides and their isosters as carbonic anhydrase inhibitors.. FUTURE MEDICINAL CHEMISTRY, vol. 6, pp. 1149-1165, ISSN:1756-8919 DOI   Accesso ONLINE all'editore

  Singh, Shalini; Supuran, Claudiu T. (2014). 3D-QSAR CoMFA studies on sulfonamide inhibitors of the Rv3588c β-carbonic anhydrase from Mycobacterium tuberculosis and design of not yet synthesized new molecules. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 29, pp. 449-455, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Sara Falsini;Sandra Ristori;Laura Ciani;Emanuela Di Cola;Claudiu T. Supuran;Annarosa Arcangeli;Martin In (2014). Time resolved SAXS to study the complexation of siRNA with cationic micelles of divalent surfactants. SOFT MATTER, vol. 10, pp. 2226-2233, ISSN:1744-683X DOI  

  A. Scozzafava;M. Passaponti;C. T. Supuran;I. Gülçin (2014). Carbonic anhydrase inhibitors: guaiacol and catechol derivatives effectively inhibit certain human carbonic anhydrase isoenzymes (hCA I, II, IX and XII).. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 1-6, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  M. Bozdag;M. Ferraroni;F. Carta;D. Vullo;L. Lucarini;E. Orlandini;A. Rossello;E. Nuti;A. Scozzafava;E. Masini;C. T. Supuran (2014). Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 57, pp. 9152-9167, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Singh, Shalini; Supuran, Claudiu T. (2014). Chemometric modeling of breast cancer associated carbonic anhydrase IX inhibitors belonging to the ureido-substituted benzene sulfonamide class. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 29, pp. 877-883, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  D'Ascenzio, Melissa; Carradori, Simone; De Monte, Celeste; Secci, Daniela; Ceruso, Mariangela; Supuran, Claudiu T. (2014). Design, synthesis and evaluation of N-substituted saccharin derivatives as selective inhibitors of tumor-associated carbonic anhydrase XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 1821-1831, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Zołnowska, Beata; Sławiński, Jarosław; Pogorzelska, Aneta; Chojnacki, Jarosław; Vullo, Daniela; Supuran, Claudiu T. (2014). Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N′-(2-arylmethylthio-4-chloro-5- methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes i and II and the transmembrane tumor-associated isozymes IX and XII. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 71, pp. 135-147, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  De Simone, Giuseppina; Pizika, Ginta; Monti, Simona Maria; Di Fiore, Anna; Ivanova, Jekaterina; Vozny, Igor; Trapencieris, Peteris; Zalubovskis, Raivis; Supuran, Claudiu T.; Alterio, Vincenzo (2014). Hydrophobic Substituents of the Phenylmethylsulfamide Moiety Can Be Used for the Development of New Selective Carbonic Anhydrase Inhibitors. BIOMED RESEARCH INTERNATIONAL, vol. 2014, pp. 523210-523220, ISSN:2314-6133 DOI   Accesso ONLINE all'editore

  Villafuerte, Francisco C.; Swietach, Pawel; Youm, Jae-Boum; Ford, Kerrie; Cardenas, Rosa; Supuran, Claudiu T.; Cobden, Philip M.; Rohling, Mala; Vaughan-Jones, Richard D (2014). Facilitation by intracellular carbonic anhydrase of Na+-HCO3- co-transport but not Na+/H+ exchange activity in the mammalian ventricular myocyte. THE JOURNAL OF PHYSIOLOGY, vol. 592, pp. 991-1007, ISSN:0022-3751 DOI  

  Pichake, Jayashree; Kharkar, Prashant S.; Ceruso, Mariangela; Supuran, Claudiu T; Toraskar, Mrunmayee P. (2014). Carbonic anhydrase inhibitors: Design, synthesis, and biological evaluation of novel sulfonyl semicarbazide derivatives. ACS MEDICINAL CHEMISTRY LETTERS, vol. 5, pp. 793-796, ISSN:1948-5875 DOI   Accesso ONLINE all'editore

  M. Ceruso;S. Antel;D. Vullo;A. Scozzafava;C. T. Supuran (2014). Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I-XIV.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 6768-6775, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  E. O. Pettersen;P. Ebbesen;R. G. Gieling;K. J. Williams;L. Dubois;P. Lambin;C. Ward;J. Meehan;I. H. Kunkler;S. P. Langdon;A. H. Ree;K. Flatmark;H. Lyng;M. J. Calzada;L. D. Peso;M. O. Landazuri;A. Görlach;H. Flamm;J. Kieninger;G. Urban;A. Weltin;D. C. Singleton;S. Haider;F. M. Buffa;A. L. Harris;A. Scozzafava;C. T. Supuran;I. Moser;G. Jobst;M. Busk;K. Toustrup;J. Overgaard;J. Alsner;J. Pouyssegur;J. Chiche;N. Mazure;I. Marchiq;S. Parks;A. Ahmed;M. Ashcroft;S. Pastorekova;Y. Cao;K. M. Rouschop;B. G. Wouters;M. Koritzinsky;H. Mujcic;D. Cojocari (2014). Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 1-33, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Davis, Rohan A.; Vullo, Daniela; Supuran, Claudiu T.; Poulsen, Sally-Ann (2014). Natural product polyamines that inhibit human carbonic anhydrases. BIOMED RESEARCH INTERNATIONAL, vol. 2014, pp. 374079-374084, ISSN:2314-6141 DOI  

  Ghorab, Mostafa M.; Alsaid, Mansour S.; Ceruso, Mariangela; Nissan, Yassin M.; Supuran, Claudiu T. (2014). Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, pp. 3684-3695, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Lock, F.E.; Mcdonald, P.C.; Lou, Y.; Serrano, I.; Chafe, S.C.; Ostlund, C.; Aparicio, S.; Winum, J.-Y.; Supuran, C.T.; Dedhar, S. (2013). Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche. ONCOGENE, vol. 32, pp. 5210-5219, ISSN:0950-9232 DOI  

  Winum, Jean-Yves; Colinas, Pedro A.; Supuran, Claudiu T. (2013). Glycosidic carbonic anhydrase IX inhibitors: A sweet approach against cancer. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1419-1426, ISSN:0968-0896 DOI  

  D. Vullo;S. Isik;S. D. Prete;V. D. Luca;V. Carginale;A. Scozzafava;C. T. Supuran;C. Capasso (2013). Anion inhibition studies of the α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 23, pp. 1636-1638, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  S. D. Prete;V. D. Luca;A. Scozzafava;V. Carginale;C. T. Supuran;C. Capasso (2013). Biochemical properties of a new α-carbonic anhydrase from the human pathogenic bacterium, Vibrio cholerae.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 23-27, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  R. Demirdağ;V. Comaklı;M. Sentürk;D. Ekinci;O. I. Küfrevioğlu;C. T. Supuran (2013). Purification and characterization of carbonic anhydrase from sheep kidney and effects of sulfonamides on enzyme activity.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1522-1525, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  C. Ward;S. P. Langdon;P. Mullen;A. L. Harris;D. J. Harrison;C. T. Supuran;I. H. Kunkler (2013). New strategies for targeting the hypoxic tumour microenvironment in breast cancer.. CANCER TREATMENT REVIEWS, vol. 39, pp. 171-179, ISSN:0305-7372 DOI   Accesso ONLINE all'editore

  A. Maresca;D. Vullo;A. Scozzafava;G. Manole;C. T. Supuran (2013). Inhibition of the β-class carbonic anhydrases from Mycobacterium tuberculosis with carboxylic acids.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. ....., pp. 392-396, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  D. Vullo;V. D. Luca;A. Scozzafava;V. Carginale;M. Rossi;C. T. Supuran;C. Capasso (2013). The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. ...., pp. 1534-1538, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  R. L. Arechederra;A. Waheed;W. S. Sly;C. T. Supuran;S. D. Minteer (2013). Effect of sulfonamides as carbonic anhydrase VA and VB inhibitors on mitochondrial metabolic energy conversion.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1544-1548, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  V. D. Luca;D. Vullo;A. Scozzafava;V. Carginale;M. Rossi;C. T. Supuran;C. Capasso (2013). An α-carbonic anhydrase from the thermophilic bacterium Sulphurihydrogenibium azorense is the fastest enzyme known for the CO(2) hydration reaction.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. ...., pp. 1465-1469, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  S. Singh;C. T. Supuran (2013). Chemometric QSAR modeling and in silico design of carbonic anhydrase inhibition of a coral secretory isoform by sulfonamide.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1495-1502, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  A. M. Marini;A. Maresca;M. Aggarwal;E. Orlandini;S. Nencetti;F. D. Settimo;S. Salerno;F. Simorini;C. L. Motta;S. Taliani;E. Nuti;A. Scozzafava;R. McKenna;A. Rossello;C. T. Supuran (2013). Tryciclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibit α- and β- carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms.. JOURNAL OF MEDICINAL CHEMISTRY, vol. ----, pp. 9619-9629, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  F. Bellissima;F. Carta;A. Innocenti;A. Scozzafava;P. Baglioni;C. T. Supuran;D. Berti (2013). Structural modulation of the biological activity of gold nanoparticles functionalized with a carbonic anhydrase inhibitor.. THE EUROPEAN PHYSICAL JOURNAL. E, SOFT MATTER, vol. 36, pp. 48-57, ISSN:1292-8941 DOI   Accesso ONLINE all'editore

  A. D. Fiore;C. Capasso;V. D. Luca;S. M. Monti;V. Carginale;C. T. Supuran;A. Scozzafava;C. Pedone;M. Rossi;G. D. Simone (2013). X-ray structure of the first `extremo-α-carbonic anhydrase', a dimeric enzyme from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1.. ACTA CRYSTALLOGRAPHICA. SECTION D, BIOLOGICAL CRYSTALLOGRAPHY, vol. 69, pp. 1150-1159, ISSN:0907-4449 DOI   Accesso ONLINE all'editore

  M. Ceruso;D. Vullo;A. Scozzafava;C. T. Supuran (2013). Sulfonamides incorporating fluorine and 1,3,5-triazine moieties are effective inhibitors of three β-class carbonic anhydrases from Mycobacterium tuberculosis.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 686-689, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  C. T. Supuran;F. Carta;A. Scozzafava (2013). Metalloenzyme inhibitors for the treatment of Gram-negative bacterial infections: a patent review (2009 - 2012).. EXPERT OPINION ON THERAPEUTIC PATENTS, pp. 777-788, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  Buanne, Pasquale; Renzone, Giovanni; Monteleone, Francesca; Vitale, Monica; Maria Monti, Simona; Sandomenico, Anna Maria; Garbi, Corrado; Montanaro, Donatella; Accardo, Marina; Troncone, Giancarlo; Zatovicova, Miriam; Csaderova, Lucia; Supuran, Claudiu T.; Pastorekova, Silvia; Scaloni, Andrea; De Simone, Giuseppina; Zambrano, Nicola (2013). Characterization of carbonic anhydrase ix interactome reveals proteins assisting its nuclear localization in hypoxic cells. JOURNAL OF PROTEOME RESEARCH, vol. 12, pp. 282-292, ISSN:1535-3893 DOI  

  Biswas, Shyamasri; Carta, Fabrizio; Scozzafava, Andrea; McKenna, Robert*; Supuran, Claudiu T. (2013). Structural effect of phenyl ring compared to thiadiazole based adamantyl-sulfonamides on carbonic anhydrase inhibition. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 2314-2318, ISSN:0968-0896 DOI  

  A. Scozzafava;C. T. Supuran;F. Carta (2013). Antiobesity carbonic anhydrase inhibitors: a literature and patent review.. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 23, pp. 725-735, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  Aksu, Kadir; Nar, Meryem; Tanc, Muhammet; Vullo, Daniela; Gülçin, Ilhami; Göksu, Süleyman; Tümer, Ferhan; Supuran, Claudiu T. (2013). Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 2925-2931, ISSN:0968-0896 DOI  

  Sławiński, Jarosław; Szafrański, Krzysztof; Vullo, Daniela; Supuran, Claudiu T. (2013). Carbonic anhydrase inhibitors. Synthesis of heterocyclic 4-substituted pyridine-3-sulfonamide derivatives and their inhibition of the human cytosolic isozymes i and II and transmembrane tumor-associated isozymes IX and XII. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 69, pp. 701-710, ISSN:0223-5234 DOI  

  M. Tanc;F. Carta;M. Bozdag;A. Scozzafava;C. T. Supuran (2013). 7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 4502-4510, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Tarko, Laszlo; Supuran, Claudiu T. (2013). QSAR studies of sulfamate and sulfamide inhibitors targeting human carbonic anhydrase isozymes I, II, IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1404-1409, ISSN:0968-0896 DOI  

  F. Carta;D. Vullo;A. Maresca;A. Scozzafava;C. T. Supuran (2013). Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 6, pp. 1564-1569, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  R. A. Davis;D. Vullo;A. Maresca;C. T. Supuran;S. Poulsen (2013). Natural product coumarins that inhibit human carbonic anhydrases.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1539-1543, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Bozdag, Murat; Dreker, Tobias; Henry, Christophe; Tosco, Paolo; Vallaro, Maura; Fruttero, Roberta; Scozzafava, Andrea; Carta, Fabrizio*; Supuran, Claudiu T. (2013). Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 23, pp. 715-719, ISSN:0960-894X DOI  

  Carta, Fabrizio; Supuran, Claudiu T (2013). Diuretics with carbonic anhydrase inhibitory action: A patent and literature review (2005-2013). EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 23, pp. 681-691, ISSN:1354-3776 DOI  

  Güzel-Akdemir, Özlen; Biswas, Shyamasri; Lastra, Katherine; Mckenna, Robert; Supuran, Claudiu T. (2013). Structural study of the location of the phenyl tail of benzene sulfonamides and the effect on human carbonic anhydrase inhibition. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 6674-6680, ISSN:0968-0896 DOI  

  D. Vullo;R. S. Sai;A. Scozzafava;C. Capasso;J. G. Ferry;C. T. Supuran (2013). Anion inhibition studies of a β-carbonic anhydrase from Clostridium perfringens.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 23, pp. 6706-6710, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Sethi, Kalyan K; Verma, Saurabh M.; Tanç, Muhammet; Carta, Fabrizio; Supuran, Claudiu T. (2013). Carbonic anhydrase inhibitors: Synthesis and inhibition of the cytosolic mammalian carbonic anhydrase isoforms I, II and VII with benzene sulfonamides incorporating 4,5,6,7-tetrachlorophthalimide moiety. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 5168-5174, ISSN:0968-0896 DOI  

  S. D. Prete;D. Vullo;V. D. Luca;V. Carginale;A. Scozzafava;C. T. Supuran;C. Capasso (2013). A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 23, pp. 4067-4071, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Gavernet, Luciana; Gonzalez Funes, José L.; Palestro, Pablo H.; Bruno Blanch, Luis E.; Estiu, Guillermina L.; Maresca, Alfonso; Barrios, Ivana; Supuran, Claudiu T. (2013). Inhibition pattern of sulfamide-related compounds in binding to carbonic anhydrase isoforms I, II, VII, XII and XIV. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1410-1418, ISSN:0968-0896 DOI  

  I. Nishimori;D. Vullo;T. Minakuchi;A. Scozzafava;C. Capasso;C. T. Supuran (2013). Restoring catalytic activity to the human carbonic anhydrase (CA) related proteins VIII, X and XI affords isoforms with high catalytic efficiency and susceptibility to anion inhibition.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 23, pp. 256-260, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  L. E. Riafrecha;O. M. Rodríguez;D. Vullo;C. T. Supuran;P. A. Colinas (2013). Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1489-1494, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  A. Maresca;D. Vullo;A. Scozzafava;C. T. Supuran (2013). Inhibition of the alpha- and beta-carbonic anhydrases from the gastric pathogen Helycobacter pylori with anions.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. ....., pp. 388-391, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  C. Alp;A. Maresca;N. A. Alp;M. S. Gültekin;D. Ekinci;A. Scozzafava;C. T. Supuran (2013). Secondary/tertiary benzenesulfonamides with inhibitory action against the cytosolic human carbonic anhydrase isoforms I and II.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. ...., pp. 294-298, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  G. Compain;A. Martin-Mingot;A. Maresca;S. Thibaudeau;C. T. Supuran (2013). Superacid synthesis of halogen containing N-substituted-4-aminobenzene sulfonamides: New selective tumor-associated carbonic anhydrase inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1555-1563, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  A. Bonneau;A. Maresca;J. Winum;C. T. Supuran (2013). Metronidazole-coumarin conjugates and 3-cyano-7-hydroxy-coumarin act as isoform-selective carbonic anhydrase inhibitors.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 28, pp. 397-401, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Lounnas, Nadia; Rosilio, Célia; Nebout, Marielle; Mary, Didier; Griessinger, Emmanuel; Neffati, Zouhour; Chiche, Johanna; Spits, Hergen; Hagenbeek, Thijs J.; Asnafi, Vahid; Poulsen, Sally-Ann; Supuran, Claudiu T.; Peyron, Jean-François; Imbert, Véronique (2013). Pharmacological inhibition of carbonic anhydrase XII interferes with cell proliferation and induces cell apoptosis in T-cell lymphomas. CANCER LETTERS, vol. 333, pp. 76-88, ISSN:0304-3835 DOI  

  Alafeefy, Ahmed M; Isik, Semra; Abdel-Aziz, Hatem A.; Ashour, Abdelkader E.; Vullo, Daniela; Al-Jaber, Nabila A.; Supuran, Claudiu T. (2013). Carbonic anhydrase inhibitors: Benzenesulfonamides incorporating cyanoacrylamide moieties are low nanomolar/subnanomolar inhibitors of the tumor-associated isoforms IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1396-1403, ISSN:0968-0896 DOI  

  Rummer, Jodie L.; Mckenzie, David J.; Innocenti, Alessio; Supuran, Claudiu T.; Brauner, Colin J. (2013). Root effect hemoglobin may have evolved to enhance general tissue oxygen delivery. SCIENCE, vol. 340, pp. 1327-1329, ISSN:0036-8075 DOI   Accesso ONLINE all'editore

  F. Carta;A. Akdemir;A. Scozzafava;E. Masini;C. T. Supuran (2013). Xanthates and Trithiocarbonates Strongly Inhibit Carbonic Anhydrases and Show Antiglaucoma Effects in Vivo.. JOURNAL OF MEDICINAL CHEMISTRY, pp. 4691-4700, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  L. Syrjänen;M. E. E;M. Hilvo;D. Vullo;F. Carta;C. T. Supuran;S. Parkkila (2013). Characterization, bioinformatic analysis and dithiocarbamate inhibition studies of two new α-carbonic anhydrases, CAH1 and CAH2, from the fruit fly Drosophila melanogaster.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1516-1521, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  F. Cottier;W. Leewattanapasuk;L. R. Kemp;M. Murphy;C. T. Supuran;O. Kurzai;F. A. Mühlschlegel (2013). Carbonic anhydrase regulation and CO(2) sensing in the fungal pathogen Candida glabrata involves a novel Rca1p ortholog.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1549-1554, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Métayer, Benoît; Martin-Mingot, Agnès; Vullo, Daniela; Supuran, Claudiu. T.; Thibaudeau, Sébastien (2013). Superacid synthesized tertiary benzenesulfonamides and benzofuzed sultams act as selective hCA IX inhibitors: Toward understanding a new mode of inhibition by tertiary sulfonamides. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 11, pp. 7540-7549, ISSN:1477-0520 DOI  

  S. M. Monti;G. D. Simone;N. A. Dathan;M. Ludwig;D. Vullo;A. Scozzafava;C. Capasso;C. T. Supuran (2013). Kinetic and anion inhibition studies of a β-carbonic anhydrase (FbiCA 1) from the C4 plant Flaveria bidentis.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 23, pp. 1626-1630, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  P. Pan;A. B. Vermelho;A. Scozzafava;S. Parkkila;C. Capasso;C. T. Supuran (2013). Anion inhibition studies of the α-carbonic anhydrase from the protozoan pathogen Trypanosoma cruzi, the causative agent of Chagas disease.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 4472-4476, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  A. Akdemir;O. Güzel-Akdemir;A. Scozzafava;C. Capasso;C. T. Supuran (2013). Inhibition of tumor-associated human carbonic anhydrase isozymes IX and XII by a new class of substituted-phenylacetamido aromatic sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 5228-5232, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  S. Carradori;C. D. Monte;M. D'Ascenzio;D. Secci;G. Celik;M. Ceruso;D. Vullo;A. Scozzafava;C. T. Supuran (2013). Salen and tetrahydrosalen derivatives act as effective inhibitors of the tumor-associated carbonic anhydrase XII--a new scaffold for designing isoform-selective inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 23, pp. 6759-6763, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Schroeder, Marie A.; Ali, Mohammad A.; Hulikova, Alzbeta; Supuran, Claudiu T.; Clarke, Kieran; Vaughan-Jones, Richard D.; Tyler, Damian J.; Swietach, Pawel (2013). Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 110, pp. E958-E967, ISSN:0027-8424 DOI   Accesso ONLINE all'editore

  Hirohashi, Noritaka; Alvarez, Luis; Shiba, Kogiku; Fujiwara, Eiji; Iwata, Yoko; Mohri, Tatsuma; Inaba, Kazuo; Chiba, Kazuyoshi; Ochi, Hiroe; Supuran, Claudiu T.; Kotzur, Nico; Kakiuchi, Yasutaka; Kaupp, U. Benjamin; Baba, Shoji A. (2013). Sperm from sneaker male squids exhibit chemotactic swarming to CO 2. CURRENT BIOLOGY, vol. 23, pp. 775-781, ISSN:0960-9822 DOI  

  Rami, Marouan; Dubois, Ludwig; Parvathaneni, Nanda-Kumar; Alterio, Vincenzo; Van Kuijk, Simon J. A.; Monti, Simona Maria; Lambin, Philippe; De Simone, Giuseppina; Supuran, Claudiu T.; Winum, Jean-Yves (2013). Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates. JOURNAL OF MEDICINAL CHEMISTRY, vol. 56, pp. 8512-8520, ISSN:0022-2623 DOI  

  Dubois, Ludwig; Peeters, Sarah G.J.A.; Van Kuijk, Simon J.A.; Yaromina, Ala; Lieuwes, Natasja G.; Saraya, Ruchi; Biemans, Rianne; Rami, Marouan; Parvathaneni, Nanda Kumar; Vullo, Daniela; Vooijs, Marc; Supuran, Claudiu T.; Winum, Jean-Yves; Lambin, Philippe (2013). Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: A new concept of dual targeting drugs. RADIOTHERAPY AND ONCOLOGY, vol. 108, pp. 523-528, ISSN:0167-8140 DOI  

  E. Masini;F. Carta;A. Scozzafava;C. T. Supuran (2013). Antiglaucoma carbonic anhydrase inhibitors: a patent review.. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 23, pp. 705-716, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  Güzel-Akdemir, Özlen; Akdemir, Atilla; Isik, Semra; Vullo, Daniela; Supuran, Claudiu T. (2013). O-Benzenedisulfonimido-sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1386-1391, ISSN:0968-0896 DOI  

  Leitans, Janis; Sprudza, Agnese; Tanc, Muhammet; Vozny, Igor; Zalubovskis, Raivis; Tars, Kaspars; Supuran, Claudiu T. (2013). 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: Solution and X-ray crystallographic studies. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 5130-5138, ISSN:0968-0896 DOI  

  Ekinci, Deniz; Fidan, Ismail; Durdagi, Serdar; Kaban, Şeniz; Supuran, Claudiu T. (2013). Kinetic and in silico analysis of thiazolidin-based inhibitors of α-carbonic anhydrase isoenzymes. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 28, pp. 370-374, ISSN:1475-6366 DOI  

  Carreyre, Hélène; Coustard, Jean-Marie; Carré, Grégoire; Vandebrouck, Clarisse; Bescond, Jocelyn; Ouédraogo, Maurice; Marrot, Jérôme; Vullo, Daniella; Supuran, Claudiu T; Thibaudeau, Sébastien (2013). Natural product hybrid and its superacid synthesized analogues: Dodoneine and its derivatives show selective inhibition of carbonic anhydrase isoforms I, III, XIII and XIV. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 3790-3794, ISSN:0968-0896 DOI  

  Carroux, Cindy J.; Rankin, Gregory M.; Moeker, Janina; Bornaghi, Laurent F.; Katneni, Kasiram; Morizzi, Julia; Charman, Susan A.; Vullo, Daniela; Supuran, Claudiu T; Poulsen, Sally-Ann (2013). A prodrug approach toward cancer-related carbonic anhydrase inhibition. JOURNAL OF MEDICINAL CHEMISTRY, vol. 56, pp. 9623-9634, ISSN:0022-2623 DOI  

  Roberto Pini; Fulvio RATTO; Francesca TATINI; Franco Fusi; Sonia CENTI; Andrea Scozzafava; Claudiu Trandafir SUPURAN; Fabrizio Carta; Sergio Capaccioli; Ewa Janina WITORT (2013). Assembly comprising an absorber of near infrared (nir) light covalently linked to an inhibitor of carbonic anhydrase. Numero: EP2964272 CNR

  P. Pan;A. B. Vermelho;G. C. Rodrigues;A. Scozzafava;M. E. E;S. Parkkila;C. Capasso;C. T. Supuran (2013). Cloning, Characterization, and Sulfonamide and Thiol Inhibition Studies of an α-Carbonic Anhydrase from Trypanosoma cruzi, the Causative Agent of Chagas Disease.. JOURNAL OF MEDICINAL CHEMISTRY, pp. 1761-1771, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  D. Vullo;V. D. Luca;A. Scozzafava;V. Carginale;M. Rossi;C. T. Supuran;C. Capasso (2013). The extremo-α-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium azorense is highly inhibited by sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 4521-4525, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Pinard, Melissa A.; Boone, Christopher D.; Rife, Brittany D.; Supuran, Claudiu T; Mckenna, Robert (2013). Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 7210-7215, ISSN:0968-0896 DOI  

  Akincioǧlu, Akin; Akbaba, Yusuf; Göçer, Hülya; Göksu, Süleyman; Gülçin, Ilhami; Supuran, Claudiu T. (2013). Novel sulfamides as potential carbonic anhydrase isoenzymes inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1379-1385, ISSN:0968-0896 DOI  

  Tania Fiaschi;Elisa Giannoni;Maria Letizia Taddei;Paolo Cirri;Alberto Marini;Gianfranco Pintus;Cristina Nativi;Barbara Richichi;Andrea Scozzafava;Fabrizio Carta;Eugenio Torre;Claudiu T. Supuran;Paola Chiarugi (2013). Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells. CELL CYCLE, vol. 12, pp. 1791-1801, ISSN:1538-4101 DOI  

  Bernadat, Guillaume; Supuran, Claudiu T.; Iorga, Bogdan I (2013). Carbonic anhydrase binding site parameterization in OPLS-AA force field. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1427-1430, ISSN:0968-0896 DOI  

  M. Pérez-Sayáns;C. T. Supuran;S. Pastorekova;J. M. Suárez-Peñaranda;G. Pilar;F. Barros-Angueira;J. M. Gándara-Rey;A. García-García (2013). The role of carbonic anhydrase IX in hypoxia control in OSCC.. JOURNAL OF ORAL PATHOLOGY & MEDICINE, vol. 42, pp. 1-8, ISSN:0904-2512 DOI   Accesso ONLINE all'editore

  T. Tuccinardi;S. Bertini;C. Granchi;G. Ortore;M. Macchia;F. Minutolo;A. Martinelli;C. T. Supuran (2013). Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1511-1515, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  CLAUDIU SUPURAN; ANDREA SCOZZAFAVA; EMANUELA MASINI; FABRIZIO CARTA; ERIK OLAI PETTERSEN; PETER EBBERSEN (2013). A CARBONIC ANHYDRASE INHIBITOR COMPRISING A DITHIOCARBAMATE. Numero: WO 2013/050426 A1 CLAUDIU SUPURAN, ANDREA SCOZZAFAVA, EMANUELA MASINI, FABRIZIO CARTA, ERIK OLAI PETTERSEN, PETER EBBERSEN

  S. D. Prete;V. D. Luca;D. Vullo;A. Scozzafava;V. Carginale;C. T. Supuran;C. Capasso (2013). Biochemical characterization of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis, PgiCA.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 532-537, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Biswas, Shyamasri; Mckenna, Robert; Supuran, Claudiu T. (2013). Effect of incorporating a thiophene tail in the scaffold of acetazolamide on the inhibition of human carbonic anhydrase isoforms I, II, IX and XII. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 23, pp. 5646-5649, ISSN:0960-894X DOI  

  Saada, Mohamed-Chiheb; Ombouma, Joanna; Montero, Jean-Louis; Supuran, Claudiu T; Winum, Jean-Yves (2013). Thiol-ene click chemistry for the synthesis of highly effective glycosyl sulfonamide carbonic anhydrase inhibitors. CHEMICAL COMMUNICATIONS, vol. 49, pp. 5699-5701, ISSN:1359-7345 DOI  

  Ulus, Ramazan; Yeşildağ, Ibrahim; Tanç, Muhammet; Bülbül, Metin; Kaya, Muharrem; Supuran, Claudiu T (2013). Synthesis of novel acridine and bis acridine sulfonamides with effective inhibitory activity against the cytosolic carbonic anhydrase isoforms II and VII. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 5799-5805, ISSN:1464-3391 DOI  

  Sethi, Kalyan K; Vullo, Daniella; Verma, Saurabh M.; Tanç, Muhammet; Carta, Fabrizio; Supuran, Claudiu T. (2013). Carbonic anhydrase inhibitors: Synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 5973-5982, ISSN:0968-0896 DOI  

  M. Ceruso;D. Vullo;A. Scozzafava;C. T. Supuran (2013). Inhibition of human carbonic anhydrase isoforms I-XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 6929-6936, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Güzel Akdemir, Ö.; Akdemir, A.; Pan, P.; Vermelho, A. B.; Parkkila, S.; Scozzafava, Andrea; Capasso, C.; Supuran, CLAUDIU TRANDAFIR (2013). A class of sulfonamides with strong inhibitory action against the α-carbonic anhydrase from Trypanosoma cruzi.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 56, pp. 5773-5781, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Del Giudice, Rita; Monti, Daria M; Truppo, Emanuela; Arciello, Angela; Supuran, Claudiu T; De Simone, Giuseppina; Monti, Simona M (2013). Human carbonic anhydrase VII protects cells from oxidative damage. BIOLOGICAL CHEMISTRY, vol. 394, pp. 1343-1348, ISSN:1437-4315 DOI  

  A. Akdemir;D. Vullo;V. D. Luca;A. Scozzafava;V. Carginale;M. Rossi;C. T. Supuran;C. Capasso (2013). The extremo-α-carbonic anhydrase (CA) from Sulfurihydrogenibium azorense, the fastest CA known, is highly activated by amino acids and amines.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 23, pp. 1087-1090, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  H. M. Said;C. Hagemann;F. Carta;A. Katzer;B. Polat;A. Staab;A. Scozzafava;J. Anacker;G. H. Vince;M. Flentje;C. T. Supuran (2013). Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 3949-3957, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Métayer, Benoît; Mingot, Agnès; Vullo, Daniela; Supuran, Claudiu T; Thibaudeau, Sébastien (2013). New superacid synthesized (fluorinated) tertiary benzenesulfonamides acting as selective hCA IX inhibitors: toward a new mode of carbonic anhydrase inhibition by sulfonamides. CHEMICAL COMMUNICATIONS, vol. 49, pp. 6015-6017, ISSN:1364-548X DOI  

  F. Carta;A. Maresca;A. Scozzafava;C. T. Supuran (2012). 5- and 6-membered (thio)lactones are prodrug type carbonic anhydrase inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, pp. 267-270, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  S. Parkkila;D. Vullo;A. Maresca;F. Carta;A. Scozzafava;C. T. Supuran (2012). Serendipitous fragment-based drug discovery: ketogenic diet metabolites and statins effectively inhibit several carbonic anhydrases.. CHEMICAL COMMUNICATIONS, vol. 48, pp. 3551-3553, ISSN:1364-548X DOI   Accesso ONLINE all'editore

  F. Carta;D. Vullo;A. Maresca;A. Scozzafava;C. T. Supuran (2012). New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, pp. 2182-2185, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  R. Gitto;F. M. Damiano;P. Mader;L. D. Luca;S. Ferro;C. T. Supuran;D. Vullo;J. Brynda;P. Rezáčová;A. Chimirri (2012). Synthesis, structure-activity relationship studies, and X-ray crystallographic analysis of arylsulfonamides as potent carbonic anhydrase inhibitors.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 55, pp. 3891-3899, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  M. Pérez-Sayáns;J. M. Suárez-Peñaranda;G. Pilar;C. T. Supuran;S. Pastorekova;F. Barros-Angueira;J. M. Gándara-Rey;A. García-García (2012). Expression of CA-IX is associated with advanced stage tumors and poor survival in oral squamous cell carcinoma patients.. JOURNAL OF ORAL PATHOLOGY & MEDICINE, vol. 41, pp. 667-674, ISSN:0904-2512 DOI   Accesso ONLINE all'editore

  A. J. Salmon;M. L. Williams;Q. K. Wu;J. Morizzi;D. Gregg;S. A. Charman;D. Vullo;C. T. Supuran;S. Poulsen (2012). Metallocene-based inhibitors of cancer-associated carbonic anhydrase enzymes IX and XII.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 55, pp. 5506-5517, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  C. T. Supuran (2012). Structure-based drug discovery of carbonic anhydrase inhibitors.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 27, pp. 0-772, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  F. Carta;C. T. Supuran;A. Scozzafava (2012). Novel therapies for glaucoma: a patent review 2007 - 2011.. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 22, pp. 79-88, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  V. Alterio;A. D. Fiore;K. D'Ambrosio;C. T. Supuran;G. D. Simone (2012). Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?. CHEMICAL REVIEWS, vol. 112, pp. 4421-4468, ISSN:0009-2665 DOI   Accesso ONLINE all'editore

  F. Allouche;F. Chabchoub;F. Carta;C. T. Supuran (2012). Synthesis of aminocyanopyrazoles via a multi-component reaction and anti-carbonic anhydrase inhibitory activity of their sulfamide derivatives against cytosolic and transmembrane isoforms.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 28, pp. 343-349, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  K. D'Ambrosio;F. Smaine;F. Carta;G. D. Simone;J. Winum;C. T. Supuran (2012). Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 55, pp. 6776-6783, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  V. Alterio;E. Langella;F. Viparelli;D. Vullo;G. Ascione;N. A. Dathan;F. M. M;C. T. Supuran;G. D. Simone;S. M. Monti (2012). Structural and inhibition insights into carbonic anhydrase CDCA1 from the marine diatom Thalassiosira weissflogii.. BIOCHIMIE, vol. 94, pp. 1232-1241, ISSN:0300-9084 DOI   Accesso ONLINE all'editore

  S. M. Monti;A. Maresca;F. Viparelli;F. Carta;G. D. Simone;F. A. Mühlschlegel;A. Scozzafava;C. T. Supuran (2012). Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, pp. 859-862, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  K. S. Hewitson;D. Vullo;A. Scozzafava;A. Mastrolorenzo;C. T. Supuran (2012). Molecular Cloning, Characterization, and Inhibition Studies of a β-Carbonic Anhydrase from Malassezia globosa, a Potential Antidandruff Target.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 55, pp. 3513-3520, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  G. Balboni;C. Congiu;V. Onnis;A. Maresca;A. Scozzafava;J. Winum;A. Maietti;C. T. Supuran (2012). Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, pp. 3063-3066, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Maresca;A. Scozzafava;S. Köhler;J. Winum;C. T. Supuran (2012). Inhibition of beta-carbonic anhydrases from the bacterial pathogen Brucella suis with inorganic anions.. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 110, pp. 36-39, ISSN:0162-0134 DOI   Accesso ONLINE all'editore

  C. T. Supuran;A. Scozzafava (2012). Heterocyclic urea derivatives and methods of use thereof (WO2010142978).. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 22, pp. 193-197, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  M. Sentürk;D. Ekinci;S. Göksu;C. T. Supuran (2012). Effects of dopaminergic compounds on carbonic anhydrase isozymes I, II, and VI.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 27, pp. 365-369, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  F. Itel;S. Al-Samir;F. Oberg;M. Chami;M. Kumar;C. T. Supuran;P. M. T;W. Meier;K. Hedfalk;G. Gros;V. Endeward (2012). CO2 permeability of cell membranes is regulated by membrane cholesterol and protein gas channels.. THE FASEB JOURNAL, vol. 26, pp. 5182-5191, ISSN:0892-6638 DOI   Accesso ONLINE all'editore

  S. Turkoglu;A. Maresca;M. Alper;F. Kockar;S. Işık;S. Sinan;O. Ozensoy;O. Arslan;C. T. Supuran (2012). Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase II: influences on the catalytic activity and affinity for inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 20, pp. 2208-2213, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  D. Can;B. Spingler;P. Schmutz;F. Mendes;P. Raposinho;C. Fernandes;F. Carta;A. Innocenti;I. Santos;C. T. Supuran;R. Alberto (2012). [(Cp-R)M(CO)(3) ] (M=Re or (99m) Tc) Arylsulfonamide, Arylsulfamide, and Arylsulfamate Conjugates for Selective Targeting of Human Carbonic Anhydrase IX.. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 51, pp. 3354-3357, ISSN:1433-7851 DOI   Accesso ONLINE all'editore

  D. Ekinci;H. Cavdar;S. Durdagi;O. Talaz;M. Sentürk;C. T. Supuran (2012). Structure-activity relationships for the interaction of 5,10-dihydroindeno[1,2-b]indole derivatives with human and bovine carbonic anhydrase isoforms I, II, III, IV and VI.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, pp. 68-73, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  K. Groves;B. Bao;J. Zhang;E. Handy;P. Kennedy;G. Cuneo;C. T. Supuran;W. Yared;J. D. Peterson;M. Rajopadhye (2012). Synthesis and evaluation of near-infrared fluorescent sulfonamide derivatives for imaging of hypoxia-induced carbonic anhydrase IX expression in tumors.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, pp. 653-657, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  J. Winum;F. Carta;C. Ward;P. Mullen;D. Harrison;S. P. Langdon;A. Cecchi;A. Scozzafava;I. Kunkler;C. T. Supuran (2012). Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22(14), pp. 4681-4685, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Ohradanova;D. Vullo;S. Pastorekova;J. Pastorek;D. J. Jackson;G. Wörheide;C. T. Supuran (2012). Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 20, pp. 1403-1410, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  H. S. Lee;T. Bae;J. Lee;D. G. Kim;Y. S. Oh;Y. Jang;J. Kim;J. Lee;A. Innocenti;C. T. Supuran;L. Chen;K. Rho;S. Kim (2012). Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug.. BMC SYSTEMS BIOLOGY, vol. 6, pp. 80-90, ISSN:1752-0509 DOI   Accesso ONLINE all'editore

  A. B. Vermelho;C. T. Supuran;J. M. Guisan (2012). Microbial enzyme: applications in industry and in bioremediation.. ENZYME RESEARCH, vol. 2012, pp. 1-3, ISSN:2090-0414 DOI   Accesso ONLINE all'editore

  D. Vullo;V. D. Luca;A. Scozzafava;V. Carginale;M. Rossi;C. T. Supuran;C. Capasso (2012). The first activation study of a bacterial carbonic anhydrase (CA). The thermostable α-CA from Sulfurihydrogenibium yellowstonense YO3AOP1 is highly activated by amino acids and amines.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, pp. 6324-6327, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  S. D. Prete;S. Isik;D. Vullo;V. D. Luca;V. Carginale;A. Scozzafava;C. T. Supuran;C. Capasso (2012). DNA Cloning, Characterization, and Inhibition Studies of an α-Carbonic Anhydrase from the Pathogenic Bacterium Vibrio cholerae.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 55, pp. 10742-10748, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  F. Carta;M. Aggarwal;A. Maresca;A. Scozzafava;R. McKenna;E. Masini;C. T. Supuran (2012). Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 55, pp. 1721-1730, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  A. Scozzafava;F. Carta;C. T. Supuran (2012). Secondary and tertiary sulfonamides: a patent review (2008 - 2012).. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 23, pp. 203-213, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  M. Bozdag;T. Dreker;C. Henry;P. Tosco;M. Vallaro;R. Fruttero;A. Scozzafava;F. Carta;C. T. Supuran (2012). Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 23, pp. 715-719, ISSN:0960-894X Accesso ONLINE all'editore

  A. Ohradanova;D. Vullo;S. Pastorekova;J. Pastorek;D. J. Jackson;G. Wörheide;C. T. Supuran (2012). Anion inhibition studies of an α-carbonic anhydrase from the living fossil Astrosclera willeyana.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, pp. 1314-1316, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  D. Vullo;V. D. Luca;A. Scozzafava;V. Carginale;M. Rossi;C. T. Supuran;C. Capasso (2012). Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, pp. 7142-7145, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  P. C. McDonald;J. Winum;C. T. Supuran;S. Dedhar (2012). Recent developments in targeting carbonic anhydrase IX for cancer therapeutics.. ONCOTARGET, vol. 3, pp. 84-97, ISSN:1949-2553

  V. D. Luca;D. Vullo;A. Scozzafava;V. Carginale;M. Rossi;C. T. Supuran;C. Capasso (2012). Anion inhibition studies of an α-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, pp. 5630-5634, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  C. T. Supuran (2012). Amide derivatives of benzene-sulfonanilide, pharmaceutical composition thereof and method for cancer treatment using the same (US20120095092).. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 22, pp. 1251-1255, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  F. Fabrizi;F. Mincione;T. Somma;G. Scozzafava;F. Galassi;E. Masini;F. Impagnatiello;C. T. Supuran (2012). A new approach to antiglaucoma drugs: carbonic anhydrase inhibitors with or without NO donating moieties. Mechanism of action and preliminary pharmacology.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 27, pp. 138-147, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  E. Truppo;C. T. Supuran;A. Sandomenico;D. Vullo;A. Innocenti;A. D. Fiore;V. Alterio;G. D. Simone;S. M. Monti (2012). Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, pp. 1560-1564, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  C. T. Supuran (2012). Inhibition of bacterial carbonic anhydrases and zinc proteases: from orphan targets to innovative new antibiotic drugs.. CURRENT MEDICINAL CHEMISTRY, vol. 19, pp. 831-844, ISSN:0929-8673

  J. Winum;A. Maresca;F. Carta;A. Scozzafava;C. T. Supuran (2012). Polypharmacology of sulfonamides: pazopanib, a multitargeted receptor tyrosine kinase inhibitor in clinical use, potently inhibits several mammalian carbonic anhydrases.. CHEMICAL COMMUNICATIONS, vol. 48, pp. 8177-8179, ISSN:1359-7345 DOI   Accesso ONLINE all'editore

  C. T. Supuran (2012). Inhibition of carbonic anhydrase IX as a novel anticancer mechanism.. WORLD JOURNAL OF CLINICAL ONCOLOGY, vol. 3, pp. 98-103, ISSN:2218-4333 Accesso ONLINE all'editore

  C. T. Supuran (2012). Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity.. EXPERT OPINION ON EMERGING DRUGS, vol. 17, pp. 11-15, ISSN:1472-8214 DOI   Accesso ONLINE all'editore

  S. Avram;A. L. Milac;F. Carta;C. T. Supuran (2012). More effective dithiocarbamate derivatives inhibiting carbonic anhydrases, generated by QSAR and computational design.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 28, pp. 350-359, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  M. Sechi;A. Innocenti;N. Pala;D. Rogolino;M. Carcelli;A. Scozzafava;C. T. Supuran (2012). Inhibition of α-class cytosolic human carbonic anhydrases I, II, IX and XII, and β-class fungal enzymes by carboxylic acids and their derivatives: new isoform-I selective nanomolar inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, pp. 5801-5806, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  E. A. Kazancıoğlu;M. Güney;M. Sentürk;C. T. Supuran (2012). Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 27, pp. 880-885, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  H. Tzoupis;G. Leonis;G. Megariotis;C. T. Supuran;T. Mavromoustakos;M. G. Papadopoulos (2012). Dual inhibitors for aspartic proteases HIV-1 PR and renin: advancements in AIDS-hypertension-diabetes linkage via molecular dynamics, inhibition assays, and binding free energy calculations.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 55, pp. 5784-5796, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  T. Rogez-Florent;S. Meignan;C. Foulon;P. Six;A. Gros;C. Bal-Mahieu;C. T. Supuran;A. Scozzafava;R. Frédérick;B. Masereel;P. Depreux;A. Lansiaux;J. Goossens;S. Gluszok;L. Goossens (2012). New selective carbonic anhydrase IX inhibitors: Synthesis and pharmacological evaluation of diarylpyrazole-benzenesulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 1451-1464, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  F. Carta;M. Aggarwal;A. Maresca;A. Scozzafava;R. McKenna;C. T. Supuran (2012). Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations.. CHEMICAL COMMUNICATIONS, vol. 48, pp. 1868-1870, ISSN:1359-7345 DOI   Accesso ONLINE all'editore

  R. G. Gieling;M. Babur;L. Mamnani;N. Burrows;B. A. Telfer;F. Carta;J. Winum;A. Scozzafava;C. T. Supuran;K. J. Williams (2012). Antimetastatic Effect of Sulfamate Carbonic Anhydrase IX Inhibitors in Breast Carcinoma Xenografts.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 55, pp. 5591-5600, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  A. D. Fiore;A. Maresca;C. T. Supuran;G. D. Simone (2012). Hydroxamate represents a versatile zinc binding group for the development of new carbonic anhydrase inhibitors.. CHEMICAL COMMUNICATIONS, vol. 48, pp. 8838-8840, ISSN:1359-7345 DOI   Accesso ONLINE all'editore

  H. Cavdar;D. Ekinci;O. Talaz;N. Saraçoğlu;M. Sentürk;C. T. Supuran (2012). α-Carbonic anhydrases are sulfatases with cyclic diol monosulfate esters.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 27, pp. 148-154, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  K. Tars;D. Vullo;A. Kazaks;J. Leitans;A. Lends;A. Grandane;R. Zalubovskis;A. Scozzafava;C. T. Supuran (2012). Sulfocoumarins (1,2-Benzoxathiine-2,2-dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 56, pp. 293-300, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  F. Carta;A. Scozzafava;C. T. Supuran (2012). Sulfonamides: a patent review (2008 - 2012).. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 22, pp. 747-758, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  A. Maresca;A. Scozzafava;D. Vullo;C. T. Supuran (2012). Dihalogenated sulfanilamides and benzolamides are effective inhibitors of the three β-class carbonic anhydrases from Mycobacterium tuberculosis.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 0-0, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  G. D. Simone;C. T. Supuran (2012). (In)organic anions as carbonic anhydrase inhibitors.. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 111, pp. 117-129, ISSN:0162-0134 DOI   Accesso ONLINE all'editore

  M. Perez-Sayans;A. Garcia-Garcia;A. Scozzafava;C. T. Supuran (2012). Inhibition of V-ATPase and carbonic anhydrases as interference strategy with tumor acidification processes.. CURRENT PHARMACEUTICAL DESIGN, vol. 18, pp. 1407-1413, ISSN:1381-6128

  F. Carta;A. Maresca;A. Scozzafava;C. T. Supuran (2012). Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 20, pp. 2266-2273, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  S. Durdagi;D. Vullo;P. Pan;N. Kähkönen;J. A. Määttä;V. P. Hytönen;A. Scozzafava;S. Parkkila;C. T. Supuran (2012). Protein-Protein Interactions: Inhibition of Mammalian Carbonic Anhydrases I-XV by the Murine Inhibitor of Carbonic Anhydrase and Other Members of the Transferrin Family.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 55, pp. 5529-5535, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Sahin H.; Can Z.; Yildiz O.; Kolayli S.; Innocenti A.; Scozzafava G.; Supuran C.T. (2012). Inhibition of carbonic anhydrase isozymes I and II with natural products extracted from plants, mushrooms and honey. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 27, pp. 395-402, ISSN:1475-6366

  Z. H. Chohan;H. A. Shad;C. T. Supuran (2012). Synthesis, characterization and biological studies of sulfonamide Schiff's bases and some of their metal derivatives.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 27, pp. 58-68, ISSN:1475-6366 Accesso ONLINE all'editore

  R. Reich;A. Hoffman;A. Veerendhar;A. Maresca;A. Innocenti;C. T. Supuran;E. Breuer (2012). Carbamoylphosphonates control tumor cell proliferation and dissemination by simultaneously inhibiting carbonic anhydrase IX and matrix metalloproteinase-2. Toward nontoxic chemotherapy targeting tumor microenvironment.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 55, pp. 7875-7882, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  S. M. Monti;C. T. Supuran;G. D. Simone (2012). Carbonic anhydrase IX as a target for designing novel anticancer drugs.. CURRENT MEDICINAL CHEMISTRY, vol. 19, pp. 821-830, ISSN:0929-8673

  J. Moeker;K. Teruya;S. Rossit;B. L. Wilkinson;M. Lopez;L. F. Bornaghi;A. Innocenti;C. T. Supuran;S. Poulsen (2012). Design and synthesis of thiourea compounds that inhibit transmembrane anchored carbonic anhydrases.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 20, pp. 2392-2404, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  A. Harju;F. Bootorabi;M. Kuuslahti;C. T. Supuran;S. Parkkila (2012). Carbonic anhydrase III: A neglected isozyme is stepping into the limelight.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 28, pp. 231-239, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  S. Singh;C. T. Supuran (2012). QSARs on human carbonic anhydrase VA and VB inhibitors of some new not yet synthesized, substituted aromatic/heterocyclic sulphonamides as anti-obesity agent.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 27, pp. 666-672, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  D. Ekinci;M. Al-Rashida;G. Abbas;M. Şentürk;C. T. Supuran (2012). Chromone containing sulfonamides as potent carbonic anhydrase inhibitors.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 27, pp. 744-747, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Z. Brzozowski;J. Sławiński;D. Vullo;C. T. Supuran (2012). Carbonic anhydrase inhibitors. Regioselective synthesis of novel series 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 56, pp. 282-291, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  F. Bootorabi;J. Jänis;V. P. Hytönen;J. Valjakka;M. Kuuslahti;D. Vullo;O. Niemelä;C. T. Supuran;S. Parkkila (2011). Acetaldehyde-derived modifications on cytosolic human carbonic anhydrases.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 26, pp. 862-870, ISSN:1475-6366 Accesso ONLINE all'editore

  M. Sentürk;I. Gülçin;S. Beydemir;O. İ. Küfrevioğlu;C. T. Supuran (2011). In Vitro inhibition of human carbonic anhydrase I and II isozymes with natural phenolic compounds.. CHEMICAL BIOLOGY & DRUG DESIGN, vol. 77, pp. 494-499, ISSN:1747-0285 DOI   Accesso ONLINE all'editore

  Burghout, Peter; Vullo, Daniela; Scozzafava, Andrea; Hermans, Peter W.M.; Supuran, Claudiu T.* (2011). Inhibition of the β-carbonic anhydrase from Streptococcus pneumoniae by inorganic anions and small molecules: Toward innovative drug design of antiinfectives?. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 19, pp. 243-248, ISSN:0968-0896 DOI  

  Y.Lou; P.C. McDonald; A.Oloumi; S.Chia; C.Ostlund; A. Ahmadi; A.Kyle; U.auf dem Keller; S.Leung; D.Huntsman; B.Clarke; B.W.Sutherland; D.Waterhouse; M.Bally; C.Roskelley; C.M. Overall; A.Minchinton; F.Pacchiano; F. Carta; A.Scozzafava; N.Touisni; J.-Y.Winum; C.T. Supuran; S.Dedhar (2011). Targeting Tumor Hypoxia: Suppression of Breast TumorGrowth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors. CANCER RESEARCH, vol. -----------------, pp. 0-0, ISSN:0008-5472 DOI   Accesso ONLINE all'editore

  M. Saada;J. Montero;D. Vullo;A. Scozzafava;J. Winum;C. T. Supuran (2011). Carbonic Anhydrase Activators: Gold Nanoparticles Coated with Derivatized Histamine, Histidine, and Carnosine Show Enhanced Activatory Effects on Several Mammalian Isoforms.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54, pp. 1170-1177, ISSN:1520-4804 DOI   Accesso ONLINE all'editore

  C. T. Supuran;A. Maresca;F. Gregáň;M. Remko (2011). Three new aromatic sulfonamide inhibitors of carbonic anhydrases I, II, IV and XII.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 28, pp. 289-293, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  claudiu supuran, andrea scozzafava, fabrizio carta (2011). CARBONIC ANHYDRASE INHIBITOR COMPRISING A DITHIOCARBAMATE. Numero: WO2013050426 (A1) SUPURAN CLAUDIU T [IT]; SCOZZAFAVA ANDREA [IT]; MASINI EMANUELA [IT]; CARTA FABRIZIO [IT]; PETTERSEN ERIK OLAI [NO]; EBBESEN PETER [DK]

  D. Ekinci;L. Karagoz;D. Ekinci;M. Senturk;C. T. Supuran (2011). Carbonic anhydrase inhibitors: in vitro inhibition of α isoforms (hCA I, hCA II, bCA III, hCA IV) by flavonoids.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 0-0, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  F. Carta;A. Innocenti;R. A. Hall;F. A. Mühlschlegel;A. Scozzafava;C. T. Supuran (2011). Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 2521-2526, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. D. Fiore;A. Maresca;V. Alterio;C. T. Supuran;G. D. Simone (2011). Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II.. CHEMICAL COMMUNICATIONS, vol. 47, pp. 11636-11638, ISSN:1359-7345 DOI   Accesso ONLINE all'editore

  R. A. Davis;A. Hofmann;A. Osman;R. A. Hall;F. A. Mühlschlegel;D. Vullo;A. Innocenti;C. T. Supuran;S. Poulsen (2011). Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54, pp. 1682-1692, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  C. T. Supuran (2011). Bacterial carbonic anhydrases as drug targets: toward novel antibiotics?. FRONTIERS IN PHARMACOLOGY, vol. 2, pp. 34-40, ISSN:1663-9812 DOI   Accesso ONLINE all'editore

  C. T. Supuran (2011). Enzyme Inhibition and more--a tribute to John Smith.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 26, pp. 301-302, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  A. Bertucci;A. Innocenti;A. Scozzafava;S. Tambutté;D. Zoccola;C. T. Supuran (2011). Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 710-714, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  D. Vullo;I. Nishimori;T. Minakuchi;A. Scozzafava;C. T. Supuran (2011). Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 3591-3595, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  E. E. Knaus;A. Innocenti;A. Scozzafava;C. T. Supuran (2011). Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 5892-5896, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Maresca;C. T. Supuran (2011). (R)-/(S)-10-camphorsulfonyl-substituted aromatic/heterocyclic sulfonamides selectively inhibit mitochondrial over cytosolic carbonic anhydrases.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 1334-1337, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  K. Dave;A. Scozzafava;D. Vullo;C. T. Supuran;M. A. Ilies (2011). Pyridinium derivatives of histamine are potent activators of cytosolic carbonic anhydrase isoforms I, II and VII.. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 9, pp. 2790-2800, ISSN:1477-0520 DOI   Accesso ONLINE all'editore

  M. Lopez;J. Trajkovic;L. F. Bornaghi;A. Innocenti;D. Vullo;C. T. Supuran;S. Poulsen (2011). Design, synthesis, and biological evaluation of novel carbohydrate-based sulfamates as carbonic anhydrase inhibitors.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54, pp. 1481-1489, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  C. T. Supuran (2011). Therapeutic compounds: patent evaluation of WO2011011652A1.. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 21, pp. 1491-1495, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  A. Scozzafava;C. T. Supuran (2011). Heterocyclic compounds and their uses: a patent evaluation of WO2010151735A2.. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 21, pp. 803-806, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  R. Gitto;F. M. Damiano;L. D. Luca;S. Ferro;D. Vullo;C. T. Supuran;A. Chimirri (2011). Synthesis and biological profile of new 1,2,3,4-tetrahydroisoquinolines as selective carbonic anhydrase inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 19, pp. 7003-7007, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  A. J. Salmon;M. L. Williams;A. Maresca;C. T. Supuran;S. Poulsen (2011). Synthesis of glycoconjugate carbonic anhydrase inhibitors by ruthenium-catalysed azide-alkyne 1,3-dipolar cycloaddition.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 6058-6061, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  F. Carta;V. Garaj;A. Maresca;J. Wagner;B. S. Avvaru;A. H. Robbins;A. Scozzafava;R. McKenna;C. T. Supuran (2011). Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 19, pp. 3105-3119, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Z. Brzozowski;J. Sławiński;M. Gdaniec;A. Innocenti;C. T. Supuran (2011). Carbonic anhydrase inhibitors. Synthesis, molecular structures, and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with novel 3-pyridinesulfonamide derivatives.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 46, pp. 4403-4410, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  A. Bertucci;S. Tambutté;C. T. Supuran;D. Allemand;D. Zoccola (2011). A new coral carbonic anhydrase in Stylophora pistillata.. MARINE BIOTECHNOLOGY, vol. 13, pp. 992-1002, ISSN:1436-2228 DOI   Accesso ONLINE all'editore

  S. Kolayli;F. Karahalil;H. Sahin;B. Dincer;C. T. Supuran (2011). Characterization and inhibition studies of an α-carbonic anhydrase from the endangered sturgeon species Acipenser gueldenstaedti.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 26, pp. 895-900, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  D. Ekinci;S. B. Ceyhun;M. Sentürk;D. Erdem;O. İ. Küfrevioğlu;C. T. Supuran (2011). Characterization and anions inhibition studies of an α-carbonic anhydrase from the teleost fish Dicentrarchus labrax.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 19, pp. 744-748, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  P. Joseph;S. Ouahrani-Bettache;J. Montero;I. Nishimori;T. Minakuchi;D. Vullo;A. Scozzafava;J. Winum;S. Köhler;C. T. Supuran (2011). A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 19, pp. 1172-1178, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  D. Neri;C. T. Supuran (2011). Interfering with pH regulation in tumours as a therapeutic strategy.. NATURE REVIEWS DRUG DISCOVERY, vol. 10, pp. 767-777, ISSN:1474-1776 DOI   Accesso ONLINE all'editore

  P. Ditte;F. Dequiedt;E. Svastova;A. Hulikova;A. Ohradanova-Repic;M. Zatovicova;L. Csaderova;J. Kopacek;C. T. Supuran;S. Pastorekova;J. Pastorek (2011). Phosphorylation of carbonic anhydrase IX controls its ability to mediate extracellular acidification in hypoxic tumors.. CANCER RESEARCH, vol. 71, pp. 7558-7567, ISSN:0008-5472 DOI   Accesso ONLINE all'editore

  N. Touisni;A. Maresca;P. C. McDonald;Y. Lou;A. Scozzafava;S. Dedhar;J. Winum;C. T. Supuran (2011). Glycosyl Coumarin Carbonic Anhydrase IX and XII Inhibitors Strongly Attenuate the Growth of Primary Breast Tumors.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54, pp. 8271-8277, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  A. Cincinelli; T. Martellini; A. Innocenti; A. Scozzafava; C.T. Supuran (2011). Purification and inhibition studies with anions and sulfonamides of an a-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 19 (6), pp. 1847-1851, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  P. Burghout;D. Vullo;A. Scozzafava;P. W. M Hermans;C. T. Supuran (2011). Inhibition of the β-carbonic anhydrase from Streptococcus pneumoniae by inorganic anions and small molecules: Toward innovative drug design of antiinfectives?. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 19, pp. 243-248, ISSN:1464-3391 Accesso ONLINE all'editore

  A. Maresca;F. Carta;D. Vullo;C. T. Supuran (2011). Dithiocarbamates strongly inhibit the β-class carbonic anhydrases from Mycobacterium tuberculosis.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 0-0, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  R. Demirdağ;E. Yerlikaya;M. Sentürk;O. İ. Küfrevioğlu;C. T. Supuran (2011). Heavy metal ion inhibition studies of human, sheep and fish α-carbonic anhydrases.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 0-0, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  C. Alp;S. Ozsoy;N. A. Alp;D. Erdem;M. S. Gültekin;O. İ. Küfrevioğlu;M. Sentürk;C. T. Supuran (2011). Sulfapyridine-like benzenesulfonamide derivatives as inhibitors of carbonic anhydrase isoenzymes I, II and VI.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 0-0, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  S. B. Oztürk;F. Topal;M. Sentürk;I. Gülçin;C. T. Supuran (2011). In vitro inhibition of α-carbonic anhydrase isozymes by some phenolic compounds.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 4259-4262, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  F. Pacchiano; F. Carta; P.C. McDonald; Y. Lou; D.Vullo; A. Scozzafava; S. Dedhar; and C.T. Supuran (2011). Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54, pp. 1896-1902, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  J. C. Morris;J. Chiche;C. Grellier;M. Lopez;L. F. Bornaghi;A. Maresca;C. T. Supuran;J. Pouysségur;S. Poulsen (2011). Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54, pp. 6905-6918, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  D. Ekinci;N. I. Kurbanoglu;E. Salamcı;M. Sentürk;C. T. Supuran (2011). Carbonic anhydrase inhibitors: inhibition of human and bovine isoenzymes by benzenesulphonamides, cyclitols and phenolic compounds.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 0-0, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  P. Mader;J. Brynda;R. Gitto;S. Agnello;P. Pachl;C. T. Supuran;A. Chimirri;P. Řezáčová (2011). Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54, pp. 2522-2526, ISSN:0022-2623 Accesso ONLINE all'editore

  I. Nishimori;T. Minakuchi;D. Vullo;A. Scozzafava;C. T. Supuran (2011). Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 19, pp. 5023-5030, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Buller F; Steiner M; Frey K; Mircsof D; Scheuermann J; Kalisch M; Buhlmann P; Supuran CT; Neri D. (2011). Selection of Carbonic Anhydrase IX Inhibitors from One Million DNA-Encoded Compounds.. ACS CHEMICAL BIOLOGY, pp. 0-0, ISSN:1554-8937

  K. Dave;M. A. Ilies;A. Scozzafava;C. Temperini;D. Vullo;C. T. Supuran (2011). An inhibitor-like binding mode of a carbonic anhydrase activator within the active site of isoform II.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 2764-2768, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  M. Rami;A. Innocenti;J. Montero;A. Scozzafava;J. Winum;C. T. Supuran (2011). Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against human α- and bacterial/fungal β-carbonic anhydrases.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 5210-5213, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  N. Hen;M. Bialer;B. Yagen;A. Maresca;M. Aggarwal;A. H. Robbins;R. McKenna;A. Scozzafava;C. T. Supuran (2011). Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54, pp. 3977-3981, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  N. Pala;R. Dallocchio;A. Dessì;A. Brancale;F. Carta;S. Ihm;A. Maresca;M. Sechi;C. T. Supuran (2011). Virtual screening-driven identification of human carbonic anhydrase inhibitors incorporating an original, new pharmacophore.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 2515-2520, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  C. T. Supuran (2011). Carbonic anhydrase inhibition with natural products: novel chemotypes and inhibition mechanisms.. MOLECULAR DIVERSITY, vol. 15, pp. 305-316, ISSN:1381-1991 DOI   Accesso ONLINE all'editore

  H. Sahin;R. Aliyazicioglu;O. Yildiz;S. Kolayli;A. Innocenti;C. T. Supuran (2011). Honey, pollen, and propolis extracts show potent inhibitory activity against the zinc metalloenzyme carbonic anhydrase.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 26, pp. 440-444, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  F. Pacchiano;F. Carta;D. Vullo;A. Scozzafava;C. T. Supuran (2011). Inhibition of β-carbonic anhydrases with ureido-substituted benzenesulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 102-105, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  O. M. Rodríguez;A. Maresca;C. A. Témpera;R. D. Bravo;P. A. Colinas;C. T. Supuran (2011). N-β-glycosyl sulfamides are selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 4447-4450, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  O. Ozensoy;M. Arslan;C. T. Supuran (2011). Carbonic anhydrase inhibitors: purification and inhibition studies of pigeon (Columba livia var. domestica) red blood cell carbonic anhydrase with sulfonamides.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 26, pp. 749-753, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  M. Lopez;H. Vu;C. K. Wang;M. G. Wolf;G. Groenhof;A. Innocenti;C. T. Supuran;S. Poulsen (2011). Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors.. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 133, pp. 18452-18462, ISSN:0002-7863 DOI   Accesso ONLINE all'editore

  C. T. Supuran (2011). Carbonic anhydrase inhibitors and activators for novel therapeutic applications.. FUTURE MEDICINAL CHEMISTRY, vol. 3, pp. 1165-1180, ISSN:1756-8919 DOI   Accesso ONLINE all'editore

  F. Liu;A. Martin-Mingot;F. Lecornué;M. Jouannetaud;A. Maresca;S. Thibaudeau;C. T. Supuran (2011). Carbonic Anhydrases inhibitory effects of new benzenesulfonamides synthesized by using superacid chemistry.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 0-0, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  S. Durdagi;M. Sentürk;D. Ekinci;H. T. Balaydın;S. Göksu;O. İ. Küfrevioğlu;A. Innocenti;A. Scozzafava;C. T. Supuran (2011). Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. --, pp. -----, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  S. Biswas;M. Aggarwal;Ö. Güzel;A. Scozzafava;R. McKenna;C. T. Supuran (2011). Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 19, pp. 3732-3738, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  M. Saada;D. Vullo;J. Montero;A. Scozzafava;J. Winum;C. T. Supuran (2011). Carbonic anhydrase I and II activation with mono- and dihalogenated histamine derivatives.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 4884-4887, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  L. Dubois;S. Peeters;N. G. Lieuwes;N. Geusens;A. Thiry;S. Wigfield;F. Carta;A. McIntyre;A. Scozzafava;J. Dogné;C. T. Supuran;A. L. Harris;B. Masereel;P. Lambin (2011). Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation.. RADIOTHERAPY AND ONCOLOGY, vol. 99, pp. 424-431, ISSN:0167-8140 DOI   Accesso ONLINE all'editore

  M. Rami;A. Maresca;F. Smaine;J. Montero;A. Scozzafava;J. Winum;C. T. Supuran (2011). Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 2975-2979, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  F. Mincione;F. Benedini;S. Biondi;A. Cecchi;C. Temperini;G. Formicola;I. Pacileo;A. Scozzafava;E. Masini;C. T. Supuran (2011). Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, pp. 3216-3221, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  F. Bootorabi;J. Jänis;E. Smith;A. Waheed;S. Kukkurainen;V. Hytönen;J. Valjakka;C. T. Supuran;D. Vullo;W. S. Sly;S. Parkkila (2010). Analysis of a shortened form of human carbonic anhydrase VII expressed in vitro compared to the full-length enzyme.. BIOCHIMIE, vol. 92, pp. 1072-1080, ISSN:0300-9084 DOI   Accesso ONLINE all'editore

  I. Nishimori;T. Minakuchi;A. Maresca;F. Carta;A. Scozzafava;C. T. Supuran (2010). The β-carbonic anhydrases from Mycobacterium tuberculosis as drug targets.. CURRENT PHARMACEUTICAL DESIGN, vol. 16, pp. 3300-3309, ISSN:1381-6128

  A.Casini; C.Temperini; C.Gabbiani; C.Supuran; L.Messori (2010). The X-ray Structure of the Adduct between NAMI-A and CarbonicAnhydrase Provides Insights into the Reactivity of this Metallodrug with Proteins. CHEMMEDCHEM, vol. 5, pp. 1989-1994, ISSN:1860-7179 DOI  

  F. Pacchiano;M. Aggarwal;B. S. Avvaru;A. H. Robbins;A. Scozzafava;R. McKenna;C. T. Supuran (2010). Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.. CHEMICAL COMMUNICATIONS, vol. 46, pp. 8371-8373, ISSN:1359-7345 DOI   Accesso ONLINE all'editore

  M. A. Esteves;O. Ortet;A. Capelo;C. T. Supuran;S. M. Marques;M. A. Santos (2010). New hydroxypyrimidinone-containing sulfonamides as carbonic anhydrase inhibitors also acting as MMP inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 3623-3627, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  R. A. Davis;A. Innocenti;S. Poulsen;C. T. Supuran (2010). Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18, pp. 14-18, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  SUPURAN CLAUDIU, DEDHAR SHOUKAT, CARTA FABRIZIO, WINUM JEAN-YVES, MCDONALD PAUL C (2010). CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY. Numero: WO2012070024 (A1) SUPURAN CLAUDIU [IT]; DEDHAR SHOUKAT [CA]; CARTA FABRIZIO [IT]; WINUM JEAN-YVES [FR]; MCDONALD PAUL C [CA]

  SUPURAN CLAUDIU; DEDHAR SHOUKAT; MCDONALD PAUL; CARTA FABRIZIO (2010). NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH. Numero: WO2012021963 (A1) SUPURAN CLAUDIU; DEDHAR SHOUKAT; MCDONALD PAUL; CARTA FABRIZIO

  A. Innocenti;S. Durdagi;N. Doostdar;T. A. Strom;A. R. Barron;C. T. Supuran (2010). Nanoscale enzyme inhibitors: fullerenes inhibit carbonic anhydrase by occluding the active site entrance.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18, pp. 2822-2828, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  O. O. Guler;G. D. Simone;C. T. Supuran (2010). Drug design studies of the novel antitumor targets carbonic anhydrase IX and XII.. CURRENT MEDICINAL CHEMISTRY, vol. 17, pp. 1516-1526, ISSN:0929-8673

  A. Maresca;A. Scozzafava;C. T. Supuran (2010). 7,8-disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 7255-7258, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  S. B. Oztürk;I. Gülçin;C. T. Supuran (2010). Carbonic anhydrase inhibitors: Inhibition of human erythrocyte isozymes I and II with a series of phenolic acids.. CHEMICAL BIOLOGY & DRUG DESIGN, vol. 75, pp. 515-520, ISSN:1747-0285 DOI   Accesso ONLINE all'editore

  F. Carta;C. Temperini;A. Innocenti;A. Scozzafava;K. Kaila;C. T. Supuran (2010). Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 53, pp. 5511-5522, ISSN:1520-4804 DOI   Accesso ONLINE all'editore

  R. Gitto;S. Agnello;S. Ferro;D. Vullo;C. T. Supuran;A. Chimirri (2010). Identification of potent and selective human carbonic anhydrase VII (hCA VII) inhibitors.. CHEMMEDCHEM, vol. 5, pp. 823-826, ISSN:1860-7179 DOI   Accesso ONLINE all'editore

  A. Maresca;C. Temperini;L. Pochet;B. Masereel;A. Scozzafava;C. T. Supuran (2010). Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 53, pp. 335-344, ISSN:1520-4804 DOI   Accesso ONLINE all'editore

  A. Innocenti;R. A. Hall;A. Scozzafava;F. A. Mühlschlegel;C. T. Supuran (2010). Carbonic anhydrase activators: activation of the beta-carbonic anhydrases from the pathogenic fungi Candida albicans and Cryptococcus neoformans with amines and amino acids.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18, pp. 1034-1037, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  J. Wagner;B. S. Avvaru;A. H. Robbins;A. Scozzafava;C. T. Supuran;R. McKenna (2010). Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18, pp. 4873-4878, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  L. Syrjänen;M. Tolvanen;M. Hilvo;A. Olatubosun;A. Innocenti;A. Scozzafava;J. Leppiniemi;B. Niederhauser;V. P. Hytönen;T. A. Gorr;S. Parkkila;C. T. Supuran (2010). Characterization of the first beta-class carbonic anhydrase from an arthropod (Drosophila melanogaster) and phylogenetic analysis of beta-class carbonic anhydrases in invertebrates.. BMC BIOCHEMISTRY, vol. 11, pp. 28-41, ISSN:1471-2091 DOI   Accesso ONLINE all'editore

  F. Kockar;A. Maresca;M. Aydin;S. Işik;S. Turkoglu;S. Sinan;O. Arslan;O. O. Güler;Y. Turan;C. T. Supuran (2010). Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18, pp. 5498-5503, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  A. Maresca;C. T. Supuran (2010). Coumarins incorporating hydroxy- and chloro-moieties selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 4511-4514, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  D. Vullo;I. Nishimori;A. Scozzafava;S. Köhler;J. Winum;C. T. Supuran (2010). Inhibition studies of a beta-carbonic anhydrase from Brucella suis with a series of water soluble glycosyl sulfanilamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 2178-2182, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Bertucci;D. Zoccola;S. Tambutté;D. Vullo;C. T. Supuran (2010). Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18, pp. 2300-2303, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  C. T. Supuran;A. D. Fiore;V. Alterio;S. M. Monti;G. D. Simone (2010). Recent advances in structural studies of the carbonic anhydrase family: the crystal structure of human CA IX and CA XIII.. CURRENT PHARMACEUTICAL DESIGN, vol. 16, pp. 3246-3254, ISSN:1381-6128

  Z. Brzozowski;J. Sławiński;A. Innocenti;C. T. Supuran (2010). Carbonic anhydrase inhibitors. Regioselective synthesis of novel 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 45, pp. 3656-3661, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  J. E. Simpson;N. M. Walker;C. T. Supuran;M. Soleimani;L. L. Clarke (2010). Putative anion transporter-1 (Pat-1, Slc26a6) contributes to intracellular pH regulation during H+-dipeptide transport in duodenal villous epithelium.. AMERICAN JOURNAL OF PHYSIOLOGY: GASTROINTESTINAL AND LIVER PHYSIOLOGY, vol. 298, pp. G683-G691, ISSN:0193-1857 DOI   Accesso ONLINE all'editore

  V. Akurathi;L. Dubois;N. G. Lieuwes;S. K. Chitneni;B. J. Cleynhens;D. Vullo;C. T. Supuran;A. M. Verbruggen;P. Lambin;G. M. Bormans (2010). Synthesis and biological evaluation of a 99mTc-labelled sulfonamide conjugate for in vivo visualization of carbonic anhydrase IX expression in tumor hypoxia.. NUCLEAR MEDICINE AND BIOLOGY, vol. 37, pp. 557-564, ISSN:0969-8051 DOI   Accesso ONLINE all'editore

  Z. Brzozowski;J. Sławiński;F. Saczewski;A. Innocenti;C. T. Supuran (2010). Carbonic anhydrase inhibitors: synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 45, pp. 2396-2404, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  S. M. Marques;E. A. Enyedy;C. T. Supuran;N. I. Krupenko;S. A. Krupenko;M. A. Santos (2010). Pteridine-sulfonamide conjugates as dual inhibitors of carbonic anhydrases and dihydrofolate reductase with potential antitumor activity.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18, pp. 5081-5089, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  A. D. Fiore;S. M. Monti;A. Innocenti;J. Winum;G. D. Simone;C. T. Supuran (2010). Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 3601-3605, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  C. T. Supuran (2010). Carbonic anhydrase inhibition/activation: trip of a scientist around the world in the search of novel chemotypes and drug targets.. CURRENT PHARMACEUTICAL DESIGN, vol. 16, pp. 3233-3245, ISSN:1381-6128

  R. Gitto;S. Agnello;S. Ferro;L. D. Luca;D. Vullo;J. Brynda;P. Mader;C. T. Supuran;A. Chimirri (2010). Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as potent carbonic anhydrase inhibitors: synthesis, biological evaluation, and enzyme--ligand X-ray studies.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 53, pp. 2401-2408, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  S. Isik;O. O. Guler;F. Kockar;M. Aydin;O. Arslan;C. T. Supuran (2010). Saccharomyces cerevisiae β-carbonic anhydrase: inhibition and activation studies.. CURRENT PHARMACEUTICAL DESIGN, vol. 16, pp. 3327-3336, ISSN:1381-6128

  A. D. Fiore;E. Truppo;C. T. Supuran;V. Alterio;N. Dathan;F. Bootorabi;S. Parkkila;S. M. Monti;G. D. Simone (2010). Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 5023-5026, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Cianchi F.; Vinci M.C.; Supuran C.T.; Peruzzi B.; De Giuli P.; Fasolis G.; Perigli G.; Pastorekova S.; Papucci L.; Pini A.; Masini E.; Puccetti L. (2010). Selective inhibition of carbonic anhydrase IX decreases cell proliferation and induces ceramide-mediated apoptosis in human cancer cells. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 334, pp. 710-719, ISSN:0022-3565

  F. Viparelli;S. M. Monti;G. D. Simone;A. Innocenti;A. Scozzafava;Y. Xu;F. M. M Morel;C. T. Supuran (2010). Inhibition of the R1 fragment of the cadmium-containing zeta-class carbonic anhydrase from the diatom Thalassiosira weissflogii with anions.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 4745-4748, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  C. T. Supuran (2010). Carbonic anhydrases: again, and again, and again.. CURRENT PHARMACEUTICAL DESIGN, vol. 16, pp. 3231-3232, ISSN:1381-6128

  L. Baranauskienė;M. Hilvo;J. Matulienė;D. Golovenko;E. Manakova;V. Dudutienė;V. Michailovienė;J. Torresan;J. Jachno;S. Parkkila;A. Maresca;C. T. Supuran;S. Gražulis;D. Matulis (2010). Inhibition and binding studies of carbonic anhydrase isozymes I, II and IX with benzimidazo[1,2-c][1,2,3]thiadiazole-7-sulphonamides.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 25, pp. 863-870, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  J. S. Wischeler;A. Innocenti;D. Vullo;A. Agrawal;S. M. Cohen;A. Heine;C. T. Supuran;G. Klebe (2010). Bidentate Zinc chelators for alpha-carbonic anhydrases that produce a trigonal bipyramidal coordination geometry.. CHEMMEDCHEM, vol. 5, pp. 1609-1615, ISSN:1860-7179 DOI   Accesso ONLINE all'editore

  H. M. Said;C. T. Supuran;C. Hageman;A. Staab;B. Polat;A. Katzer;A. Scozzafava;J. Anacker;M. Flentje;D. Vordermark (2010). Modulation of carbonic anhydrase 9 (CA9) in human brain cancer.. CURRENT PHARMACEUTICAL DESIGN, vol. 16, pp. 3288-3299, ISSN:1381-6128

  D. Ekinci;H. Cavdar;O. Talaz;M. Sentürk;C. T. Supuran (2010). NO-releasing esters show carbonic anhydrase inhibitory action against human isoforms I and II.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18, pp. 3559-3563, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  D. Ekinci;M. Sentürk;S. Beydemir;O. I. Küfrevioğlu;C. T. Supuran (2010). An alternative purification method for human serum paraoxonase 1 and its interactions with sulfonamides.. CHEMICAL BIOLOGY & DRUG DESIGN, vol. 76, pp. 552-558, ISSN:1747-0285 DOI   Accesso ONLINE all'editore

  A. Innocenti;C. T. Supuran (2010). Paraoxon, 4-nitrophenyl phosphate and acetate are substrates of α- but not of β-, γ- and ζ-carbonic anhydrases.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 6208-6212, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  M. Lopez;A. J. Salmon;C. T. Supuran;S. Poulsen (2010). Carbonic anhydrase inhibitors developed through 'click tailing'.. CURRENT PHARMACEUTICAL DESIGN, vol. 16, pp. 3277-3287, ISSN:1381-6128

  O. Güzel;A. Innocenti;D. Vullo;A. Scozzafava;C. T. Supuran (2010). 3-phenyl-1H-indole-5-sulfonamides: structure-based drug design of a promising class of carbonic anhydrase inhibitors.. CURRENT PHARMACEUTICAL DESIGN, vol. 16, pp. 3317-3326, ISSN:1381-6128

  L. Gavernet;J. L. Gonzalez;L. B. Blanch;G. Estiu;A. Maresca;C. T. Supuran (2010). Affinity of sulfamates and sulfamides to carbonic anhydrase II isoform: experimental and molecular modeling approaches.. JOURNAL OF CHEMICAL INFORMATION AND MODELING, vol. 50, pp. 1113-1122, ISSN:1549-960X DOI   Accesso ONLINE all'editore

  M. Lopez;L. F. Bornaghi;A. Innocenti;D. Vullo;S. A. Charman;C. T. Supuran;S. Poulsen (2010). Sulfonamide linked neoglycoconjugates--a new class of inhibitors for cancer-associated carbonic anhydrases.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 53, pp. 2913-2926, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  A. Innocenti;S. B. Oztürk;I. Gülçin;C. T. Supuran (2010). Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18, pp. 2159-2164, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Innocenti;A. Scozzafava;S. Parkkila;C. T. Supuran (2010). The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 53, pp. 850-854, ISSN:1520-4804 DOI   Accesso ONLINE all'editore

  A. Innocenti;I. Gülçin;A. Scozzafava;C. T. Supuran (2010). Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 5050-5053, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  B. S. Avvaru;J. M. Wagner;A. Maresca;A. Scozzafava;A. H. Robbins;C. T. Supuran;R. McKenna (2010). Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 4376-4381, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  O. Güzel;A. Maresca;R. A. Hall;A. Scozzafava;A. Mastrolorenzo;F. A. Mühlschlegel;C. T. Supuran (2010). Carbonic anhydrase inhibitors. The beta-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamides.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 2508-2511, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  G. D. Simone;C. T. Supuran (2010). Carbonic anhydrase IX: Biochemical and crystallographic characterization of a novel antitumor target.. BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1804, pp. 404-409, ISSN:0006-3002 DOI   Accesso ONLINE all'editore

  P. Joseph;F. Turtaut;S. Ouahrani-Bettache;J. Montero;I. Nishimori;T. Minakuchi;D. Vullo;A. Scozzafava;S. Köhler;J. Winum;C. T. Supuran (2010). Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 53, pp. 2277-2285, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  S. Gluszok;R. Frédérick;C. Foulon;F. Klupsch;C. T. Supuran;D. Vullo;A. Scozzafava;J. Goossens;B. Masereel;P. Depreux;L. Goossens (2010). Design, solid-phase synthesis, and biological evaluation of novel 1,5-diarylpyrrole-3-carboxamides as carbonic anhydrase IX inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18, pp. 7392-7401, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  M. Feldshtein;S. Elkrinawi;B. Yerushalmi;B. Marcus;D. Vullo;H. Romi;R. Ofir;D. Landau;S. Sivan;C. T. Supuran;O. S. Birk (2010). Hyperchlorhidrosis caused by homozygous mutation in CA12, encoding carbonic anhydrase XII.. AMERICAN JOURNAL OF HUMAN GENETICS, vol. 87, pp. 713-720, ISSN:0002-9297 DOI   Accesso ONLINE all'editore

  J. Winum;S. Köhler;C. T. Supuran (2010). Brucella carbonic anhydrases: new targets for designing anti-infective agents.. CURRENT PHARMACEUTICAL DESIGN, vol. 16, pp. 3310-3316, ISSN:1381-6128

  V. Alterio;S. M. Monti;E. Truppo;C. Pedone;C. T. Supuran;G. D. Simone (2010). The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex.. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 8, pp. 3528-3533, ISSN:1477-0520 DOI   Accesso ONLINE all'editore

  A. Innocenti;A. Scozzafava;C. T. Supuran (2010). Carbonic anhydrase inhibitors. Inhibition of transmembrane isoforms IX, XII, and XIV with less investigated anions including trithiocarbonate and dithiocarbamate.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 1548-1550, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Scozzafava;C. T. Supuran (2010). Carbonic anhydrase inhibitors. X-ray crystal studies of the carbonic anhydrase II-trithiocarbonate adduct--an inhibitor mimicking the sulfonamide and urea binding to the enzyme.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 474-478, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  A. Innocenti;W. Leewattanapasuk;G. Manole;A. Scozzafava;F. A. Mühlschlegel;C. T. Supuran (2010). Carbonic anhydrase activators: Activation of the beta-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acids.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 20, pp. 1701-1704, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  A. Maresca;C. Temperini;H. Vu;N. B. Pham;S. Poulsen;A. Scozzafava;R. J. Quinn;C. T. Supuran (2009). Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors.. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 131, pp. 3057-3062, ISSN:0002-7863 DOI   Accesso ONLINE all'editore

  Almstedt K; Rafstedt T; Supuran CT; Carlsson U; Hammarström P. (2009). Small-molecule suppression of misfolding of mutated human carbonic anhydrase II linked to marble brain disease.. BIOCHEMISTRY, pp. 5358-5364, ISSN:0006-2960

  M. Abdo;D. Vullo;M. Saada;J. Montero;A. Scozzafava;J. Winum;C. T. Supuran (2009). Carbonic anhydrase activators: activation of human isozymes I, II and IX with phenylsulfonylhydrazido l-histidine derivatives.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 2440-2443, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  S. Rusconi;M. L. Cicero;O. Viganò;F. Sirianni;E. Bulgheroni;S. Ferramosca;A. Bencini;A. Bianchi;L. Ruiz;C. Cabrera;J. Martinez-Picado;C. T. Supuran;M. Galli (2009). New macrocyclic amines showing activity as HIV entry inhibitors against wild type and multi-drug resistant viruses.. MOLECULES, vol. 14, pp. 1927-1937, ISSN:1420-3049 DOI   Accesso ONLINE all'editore

  Claudiu T. Supuran (2009). Fluorescent- and Spin-Labeled Sulfonamides as Probe for Carbonic Anhydrase IX. In: Cecchi, Alessandro*. Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications, pp. 223-239 John Wiley & Sons, Inc., ISBN:9780470275009. DOI   Accesso ONLINE all'editore

  R. M. Vitale;V. Alterio;A. Innocenti;J. Winum;S. M. Monti;G. D. Simone;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 52, pp. 5990-5998, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  B. T. Loughrey;M. L. Williams;P. C. Healy;A. Innocenti;D. Vullo;C. T. Supuran;P. G. Parsons;S. Poulsen (2009). Novel organometallic cationic ruthenium(II) pentamethylcyclopentadienyl benzenesulfonamide complexes targeted to inhibit carbonic anhydrase.. JBIC, vol. 14, pp. 935-945, ISSN:0949-8257 DOI   Accesso ONLINE all'editore

  O. Güzel;A. Innocenti;A. Scozzafava;A. Salman;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, pp. 4894-4899, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  J. Winum;A. Innocenti;A. Scozzafava;J. Montero;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isoforms I and II and transmembrane, tumor-associated isoforms IX and XII with boronic acids.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, pp. 3649-3652, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  M. Lopez;B. Paul;A. Hofmann;J. Morizzi;Q. K. Wu;S. A. Charman;A. Innocenti;D. Vullo;C. T. Supuran;S. Poulsen (2009). S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 52, pp. 6421-6432, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  T. Minakuchi;I. Nishimori;D. Vullo;A. Scozzafava;C. T. Supuran (2009). Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 52, pp. 2226-2232, ISSN:1520-4804 DOI   Accesso ONLINE all'editore

  A. D. Fiore;S. M. Monti;M. Hilvo;S. Parkkila;V. Romano;A. Scaloni;C. Pedone;A. Scozzafava;C. T. Supuran;G. D. Simone (2009). Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide.. PROTEINS, vol. 74, pp. 164-175, ISSN:1097-0134 DOI   Accesso ONLINE all'editore

  F. Carta;A. Maresca;A. Scozzafava;D. Vullo;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XII over the cytosolic isoforms I and II.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, pp. 7093-7099, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  T. A. Coban;S. Beydemir;I. Gülcin;I. Gücin;D. Ekinci;A. Innocenti;D. Vullo;C. T. Supuran (2009). Sildenafil is a strong activator of mammalian carbonic anhydrase isoforms I-XIV.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, pp. 5791-5795, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  P. Swietach;S. Patiar;C. T. Supuran;A. L. Harris;R. D. Vaughan-Jones (2009). The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 284, pp. 20299-20310, ISSN:0021-9258 DOI   Accesso ONLINE all'editore

  A. Thiry;A. Delayen;L. Goossens;R. Houssin;M. Ledecq;A. Frankart;J. Dogné;J. Wouters;C. T. Supuran;J. Hénichart;B. Masereel (2009). Synthesis and biological evaluation of a new family of anti-benzylanilinosulfonamides as CA IX inhibitors.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 44, pp. 511-518, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  D. Vomasta;A. Innocenti;B. König;C. T. Supuran (2009). Carbonic anhydrase inhibitors: two-prong versus mono-prong inhibitors of isoforms I, II, IX, and XII exemplified by photochromic cis-1,2-alpha-dithienylethene derivatives.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 1283-1286, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  J. Winum;A. Innocenti;D. Vullo;J. Montero;C. T. Supuran (2009). Carbonic anhydrase inhibitors; fluorinated phenyl sulfamates show strong inhibitory activity and selectivity for the inhibition of the tumor-associated isozymes IX and XII over the cytosolic ones I and II.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 5082-5085, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Maresca;F. Carta;D. Vullo;A. Scozzafava;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Inhibition of the Rv1284 and Rv3273 beta-carbonic anhydrases from Mycobacterium tuberculosis with diazenylbenzenesulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 4929-4932, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Innocenti;A. Scozzafava;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 1855-1857, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  Cianchi F; Battisti N; Vinci MC; Supuran C; Peruzzi B; De Giuli P. Fasolis G; Perigli G; Pastorekova S; Masini E; Puccetti L (2009). Carbonic anhydrase inhibitors induce ceramide-mediated apoptosis in renal cancer cells.. In: II Congresso del Gruppo Oncologico Chirurgico Cooperativo Italiano, Firenze, 6-7 Novembre, pp. 53-53.

  A. Innocenti;M. Hilvo;S. Parkkila;A. Scozzafava;C. T. Supuran (2009). Carbonic anhydrase activators. Activation of the membrane-associated isoform XV with amino acids and amines.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 3430-3433, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  A. Innocenti;J. Winum;R. A. Hall;F. A. Mühlschlegel;A. Scozzafava;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Inhibition of the fungal beta-carbonic anhydrases from Candida albicans and Cryptococcus neoformans with boronic acids.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 2642-2645, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  M. Sentürk;I. Gülçin;A. Daştan;O. I. Küfrevioğlu;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, pp. 3207-3211, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  R. M. Steele;F. Benedini;S. Biondi;V. Borghi;L. Carzaniga;F. Impagnatiello;D. Miglietta;W. K. M;R. Rajapakse;A. Cecchi;C. Temperini;C. T. Supuran (2009). Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 6565-6570, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  C. Schlicker;R. A. Hall;D. Vullo;S. Middelhaufe;M. Gertz;C. T. Supuran;F. A. Mühlschlegel;C. Steegborn (2009). Structure and inhibition of the CO2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformans.. JOURNAL OF MOLECULAR BIOLOGY, vol. 385, pp. 1207-1220, ISSN:0022-2836 DOI   Accesso ONLINE all'editore

  G. Nasr;E. Petit;C. T. Supuran;J. Winum;M. Barboiu (2009). Carbonic anhydrase II-induced selection of inhibitors from a dynamic combinatorial library of Schiff's bases.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 6014-6017, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  J. Winum;S. Poulsen;C. T. Supuran (2009). Therapeutic applications of glycosidic carbonic anhydrase inhibitors.. MEDICINAL RESEARCH REVIEWS, vol. 29, pp. 419-435, ISSN:0198-6325 DOI   Accesso ONLINE all'editore

  A. Innocenti;W. Leewattanapasuk;F. A. Mühlschlegel;A. Mastrolorenzo;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the pathogenic yeast Candida glabrata with anions.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 4802-4805, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  O. Güzel;A. Maresca;A. Scozzafava;A. Salman;A. T. Balaban;C. T. Supuran (2009). Discovery of low nanomolar and subnanomolar inhibitors of the mycobacterial beta-carbonic anhydrases Rv1284 and Rv3273.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 52, pp. 4063-4067, ISSN:1520-4804 DOI   Accesso ONLINE all'editore

  A. Bertucci;A. Innocenti;D. Zoccola;A. Scozzafava;D. Allemand;S. Tambutté;C. T. Supuran (2009). Carbonic anhydrase inhibitors: inhibition studies of a coral secretory isoform with inorganic anions.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 650-653, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  I. Nishimori;T. Minakuchi;S. Onishi;D. Vullo;A. Cecchi;A. Scozzafava;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Cloning, characterization and inhibition studies of the cytosolic isozyme III with anions.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 24, pp. 70-76, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  S. Durdagi;C. T. Supuran;T. A. Strom;N. Doostdar;M. K. Kumar;A. R. Barron;T. Mavromoustakos;M. G. Papadopoulos (2009). In silico drug screening approach for the design of magic bullets: a successful example with anti-HIV fullerene derivatized amino acids.. JOURNAL OF CHEMICAL INFORMATION AND MODELING, vol. 49, pp. 1139-1143, ISSN:1549-960X DOI   Accesso ONLINE all'editore

  L. Ciani;A. Cecchi;C. Temperini;C. T. Supuran;S. Ristori (2009). Dissecting the inhibition mechanism of cytosolic versus transmembrane carbonic anhydrases by ESR.. JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL, vol. 113, pp. 13998-14005, ISSN:1520-6106 DOI   Accesso ONLINE all'editore

  V. Alterio;M. Hilvo;A. D. Fiore;C. T. Supuran;P. Pan;S. Parkkila;A. Scaloni;J. Pastorek;S. Pastorekova;C. Pedone;A. Scozzafava;S. M. Monti;G. D. Simone (2009). Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX.. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 106, pp. 16233-16238, ISSN:1091-6490 DOI   Accesso ONLINE all'editore

  M. Hilvo;A. M. Salzano;A. Innocenti;M. S. Kulomaa;A. Scozzafava;A. Scaloni;S. Parkkila;C. T. Supuran (2009). Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 52, pp. 646-654, ISSN:1520-4804 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Cecchi;A. Scozzafava;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the difference.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, pp. 1214-1221, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  A. Hulikova;M. Zatovicova;E. Svastova;P. Ditte;R. Brasseur;R. Kettmann;C. T. Supuran;J. Kopacek;J. Pastorek;S. Pastorekova (2009). Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX.. FEBS LETTERS, vol. 583, pp. 3563-3568, ISSN:0014-5793 DOI   Accesso ONLINE all'editore

  I. Nishimori;T. Minakuchi;D. Vullo;A. Scozzafava;A. Innocenti;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 52, pp. 3116-3120, ISSN:1520-4804 DOI   Accesso ONLINE all'editore

  J. Winum;J. Montero;D. Vullo;C. T. Supuran (2009). Carbonic anhydrase inhibitors: glycosylsulfanilamides act as subnanomolar inhibitors of the human secreted isoform VI.. CHEMICAL BIOLOGY & DRUG DESIGN, vol. 74, pp. 636-639, ISSN:1747-0285 DOI   Accesso ONLINE all'editore

  A. Innocenti;R. A. Hall;C. Schlicker;F. A. Mühlschlegel;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, pp. 2654-2657, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  F. Carta;A. Maresca;A. S. Covarrubias;S. L. Mowbray;T. A. Jones;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 6649-6654, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Thiry;M. Ledecq;A. Cecchi;R. Frederick;J. Dogné;C. T. Supuran;J. Wouters;B. Masereel (2009). Ligand-based and structure-based virtual screening to identify carbonic anhydrase IX inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, pp. 553-557, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;C. T. Supuran;T. B. Hadda;F. Nasim;K. M. Khan (2009). Metal based isatin-derived sulfonamides: their synthesis, characterization, coordination behavior and biological activity.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 24, pp. 859-870, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  F. Carta;B. Pothen;A. Maresca;M. Tiwari;V. Singh;C. T. Supuran (2009). Carbonic anhydrase inhibitors: inhibition of cytosolic carbonic anhydrase isozymes II and VII with simple aromatic sulfonamides and some azo dyes.. CHEMICAL BIOLOGY & DRUG DESIGN, vol. 74, pp. 196-202, ISSN:1747-0285 DOI   Accesso ONLINE all'editore

  R. Gitto;S. Ferro;S. Agnello;L. D. Luca;G. D. Sarro;E. Russo;D. Vullo;C. T. Supuran;A. Chimirri (2009). Synthesis and evaluation of pharmacological profile of 1-aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, pp. 3659-3664, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  S. Isik;F. Kockar;M. Aydin;O. Arslan;O. O. Guler;A. Innocenti;A. Scozzafava;C. T. Supuran (2009). Carbonic anhydrase activators: activation of the beta-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 1662-1665, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  A. Innocenti;M. Hilvo;S. Parkkila;A. Scozzafava;C. T. Supuran (2009). Carbonic anhydrase inhibitors: the membrane-associated isoform XV is highly inhibited by inorganic anions.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 1155-1158, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  A. Innocenti;R. A. Hall;C. Schlicker;A. Scozzafava;C. Steegborn;F. A. Mühlschlegel;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, pp. 4503-4509, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  G. D. Simone;A. Scozzafava;C. T. Supuran (2009). Which carbonic anhydrases are targeted by the antiepileptic sulfonamides and sulfamates?. CHEMICAL BIOLOGY & DRUG DESIGN, vol. 74, pp. 317-321, ISSN:1747-0285 DOI   Accesso ONLINE all'editore

  A. Bertucci;A. Innocenti;D. Zoccola;A. Scozzafava;S. Tambutté;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, pp. 5054-5058, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  M. Singer;M. Lopez;L. F. Bornaghi;A. Innocenti;D. Vullo;C. T. Supuran;S. Poulsen (2009). Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 2273-2276, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  G. Nasr;E. Petit;D. Vullo;J. Winum;C. T. Supuran;M. Barboiu (2009). Carbonic anhydrase-encoded dynamic constitutional libraries: toward the discovery of isozyme-specific inhibitors.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 52, pp. 4853-4859, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  S. Parkkila;A. Innocenti;H. Kallio;M. Hilvo;A. Scozzafava;C. T. Supuran (2009). The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 4102-4106, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  O. Güzel;A. Innocenti;A. Scozzafava;A. Salman;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 3170-3173, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  S. M. I Morsy;A. M. Badawi;A. Cecchi;A. Scozzafava;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Biphenylsulfonamides with inhibitory action towards the transmembrane, tumor-associated isozymes IX possess cytotoxic activity against human colon, lung and breast cancer cell lines.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 24, pp. 499-505, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  L. Crocetti;A. Maresca;C. Temperini;R. A. Hall;A. Scozzafava;F. A. Mühlschlegel;C. T. Supuran (2009). A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 1371-1375, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  O. Güzel;A. Innocenti;R. A. Hall;A. Scozzafava;F. A. Mühlschlegel;C. T. Supuran (2009). Carbonic anhydrase inhibitors. The nematode alpha-carbonic anhydrase of Caenorhabditis elegans CAH-4b is highly inhibited by 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, pp. 3212-3215, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  S. Isik;F. Kockar;M. Aydin;O. Arslan;O. O. Guler;A. Innocenti;A. Scozzafava;C. T. Supuran (2009). Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, pp. 1158-1163, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Cecchi;A. Scozzafava;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Comparison of chlorthalidone and indapamide X-ray crystal structures in adducts with isozyme II: when three water molecules and the keto-enol tautomerism make the difference.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 52, pp. 322-328, ISSN:1520-4804 DOI   Accesso ONLINE all'editore

  A. Innocenti;S. Pastorekova;J. Pastorek;A. Scozzafava;G. D. Simone;C. T. Supuran (2009). The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 5825-5828, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  O. Güzel;A. Maresca;A. Scozzafava;A. Salman;A. T. Balaban;C. T. Supuran (2009). Carbonic anhydrase inhibitors. Synthesis of 2,4,6-trimethylpyridinium derivatives of 2-(hydrazinocarbonyl)-3-aryl-1H-indole-5-sulfonamides acting as potent inhibitors of the tumor-associated isoform IX and XII.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 2931-2934, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  P. Ebbesen;E. O. Pettersen;T. A. Gorr;G. Jobst;K. Williams;J. Kieninger;R. H. Wenger;S. Pastorekova;L. Dubois;P. Lambin;B. G. Wouters;T. V. Den Beucken;C. T. Supuran;L. Poellinger;P. Ratcliffe;A. Kanopka;A. Görlach;M. Gasmann;A. L. Harris;P. Maxwell;A. Scozzafava (2009). Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 24 Suppl 1, pp. 1-39, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  L. Dubois;N. G. Lieuwes;A. Maresca;A. Thiry;C. T. Supuran;A. Scozzafava;B. G. Wouters;P. Lambin (2009). Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model.. RADIOTHERAPY AND ONCOLOGY, vol. 92, pp. 423-428, ISSN:0167-8140 DOI   Accesso ONLINE all'editore

  S. Singh;P. V. Khadikar;A. Scozzafava;C. T. Supuran (2009). QSAR studies for the inhibition of the transmembrane carbonic anhydrase isozyme XIV with sulfonamides using PRECLAV software.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 24, pp. 337-349, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  J. Winum;A. Scozzafava;J. Montero;C. T. Supuran (2009). Inhibition of carbonic anhydrase IX: a new strategy against cancer.. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol. 9, pp. 693-702, ISSN:1871-5206

  S. Isik;F. Kockar;O. Arslan;O. O. Guler;A. Innocenti;C. T. Supuran (2008). Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with anions.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 6327-6331, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Maresca;C. T. Supuran (2008). Muscarinic acetylcholine receptors as therapeutic targets for obesity.. EXPERT OPINION ON THERAPEUTIC TARGETS, vol. 12, pp. 1167-1175, ISSN:1472-8222 Accesso ONLINE all'editore

  M. Barathova;M. Takacova;T. Holotnakova;A. Gibadulinova;A. Ohradanova;M. Zatovicova;A. Hulikova;J. Kopacek;S. Parkkila;C. T. Supuran;S. Pastorekova;J. Pastorek (2008). Alternative splicing variant of the hypoxia marker carbonic anhydrase IX expressed independently of hypoxia and tumour phenotype.. BRITISH JOURNAL OF CANCER, vol. 98, pp. 129-136, ISSN:0007-0920 DOI   Accesso ONLINE all'editore

  A. Moya;S. Tambutté;A. Bertucci;E. Tambutté;S. Lotto;D. Vullo;C. T. Supuran;D. Allemand;D. Zoccola (2008). Carbonic anhydrase in the scleractinian coral Stylophora pistillata: characterization, localization, and role in biomineralization.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 283, pp. 25475-25484, ISSN:0021-9258 DOI   Accesso ONLINE all'editore

  P. Swietach;S. Wigfield;C. T. Supuran;A. L. Harris;R. D. Vaughan-Jones (2008). Cancer-associated, hypoxia-inducible carbonic anhydrase IX facilitates CO2 diffusion.. BJU INTERNATIONAL, vol. 101 Suppl 4, pp. 22-24, ISSN:1464-4096 DOI   Accesso ONLINE all'editore

  A. Thiry;C. T. Supuran;B. Masereel;J. Dogné (2008). Recent developments of carbonic anhydrase inhibitors as potential anticancer drugs.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 51, pp. 3051-3056, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  J. Winum;M. Rami;A. Scozzafava;J. Montero;C. Supuran (2008). Carbonic anhydrase IX: a new druggable target for the design of antitumor agents.. MEDICINAL RESEARCH REVIEWS, vol. 28, pp. 445-463, ISSN:0198-6325 DOI   Accesso ONLINE all'editore

  G. D. Simone;A. D. Fiore;C. T. Supuran (2008). Are carbonic anhydrase inhibitors suitable for obtaining antiobesity drugs?. CURRENT PHARMACEUTICAL DESIGN, vol. 14, pp. 655-660, ISSN:1381-6128

  J. Singh;S. Singh;R. Mishra;P. V. Khadikar;C. T. Supuran;B. W. Clare;M. Lakhwani (2008). Estimation of human carbonic anhydrase II inhibition using topological indices and their combination with quantum-theoretical descriptors.. MEDICINAL CHEMISTRY, vol. 4, pp. 30-66, ISSN:1573-4064

  S. Pastorekova;D. Vullo;I. Nishimori;A. Scozzafava;J. Pastorek;C. T. Supuran (2008). Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 16, pp. 3530-3536, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  C. T. Supuran (2008). Development of small molecule carbonic anhydrase IX inhibitors.. BJU INTERNATIONAL, vol. 101 Suppl 4, pp. 39-40, ISSN:1464-4096 DOI   Accesso ONLINE all'editore

  L. W. Lawrence;D. S. Fischer;C. M. Sharland;M. Trusselle;P. A. Foster;S. K. Chander;A. D. Fiore;C. T. Supuran;G. D. Simone;A. Purohit;M. J. Reed;B. V. L (2008). Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography.. MOLECULAR CANCER THERAPEUTICS, vol. 7, pp. 2435-2444, ISSN:1535-7163 DOI   Accesso ONLINE all'editore

  J. Singh;B. Shaik;S. Singh;V. K. Agrawal;P. V. Khadikar;O. Deeb;C. T. Supuran (2008). Comparative QSAR study on para-substituted aromatic sulphonamides as CAII inhibitors: information versus topological (distance-based and connectivity) indices.. CHEMICAL BIOLOGY & DRUG DESIGN, vol. 71, pp. 244-259, ISSN:1747-0285 DOI   Accesso ONLINE all'editore

  A. Cecchi;C. T. Supuran (2008). Fluorescence- and spin-labeled carbonic anhydrase inhibitors.. CURRENT PHARMACEUTICAL DESIGN, vol. 14, pp. 699-707, ISSN:1381-6128

  C. Temperini;A. Cecchi;N. A. Boyle;A. Scozzafava;J. E. Cabeza;P. Wentworth;G. M. Blackburn;C. T. Supuran (2008). Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 999-1005, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  O. Güzel;C. Temperini;A. Innocenti;A. Scozzafava;A. Salman;C. T. Supuran (2008). Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 152-158, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  G. L. Almajan;S. Barbuceanu;A. Innocenti;A. Scozzafava;C. T. Supuran (2008). Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II and IX with some 1,3,4-oxadiazole- and 1,2,4-triazole-thiols.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 23, pp. 101-107, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  M. Rami;J. Winum;A. Innocenti;J. Montero;A. Scozzafava;C. T. Supuran (2008). Carbonic anhydrase inhibitors: copper(II) complexes of polyamino-polycarboxylamido aromatic/heterocyclic sulfonamides are very potent inhibitors of the tumor-associated isoforms IX and XII.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 836-841, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  A. Innocenti;D. Vullo;A. Scozzafava;C. T. Supuran (2008). Carbonic anhydrase inhibitors: inhibition of mammalian isoforms I-XIV with a series of substituted phenols including paracetamol and salicylic acid.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 16, pp. 7424-7428, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  M. Rami;A. Cecchi;J. Montero;A. Innocenti;D. Vullo;A. Scozzafava;J. Winum;C. T. Supuran (2008). Carbonic anhydrase inhibitors: design of membrane-impermeant copper(II) complexes of DTPA-, DOTA-, and TETA-tailed sulfonamides targeting the tumor-associated transmembrane isoform IX.. CHEMMEDCHEM, vol. 3, pp. 1780-1788, ISSN:1860-7179 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;C. T. Supuran (2008). Structure and biological properties of first row d-transition metal complexes with N-substituted sulfonamides.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 23, pp. 240-251, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  J. Dogné;A. Thiry;C. T. Supuran (2008). Carbonic anhydrase inhibition: insight into non-COX-2 pharmacological effect of some coxibs.. CURRENT PHARMACEUTICAL DESIGN, vol. 14, pp. 679-684, ISSN:1381-6128

  F. Bootorabi;J. Jänis;J. Valjakka;S. Isoniemi;P. Vainiotalo;D. Vullo;C. T. Supuran;A. Waheed;W. S. Sly;O. Niemelä;S. Parkkila (2008). Modification of carbonic anhydrase II with acetaldehyde, the first metabolite of ethanol, leads to decreased enzyme activity.. BMC BIOCHEMISTRY, vol. 9, pp. 32-40, ISSN:1471-2091 DOI   Accesso ONLINE all'editore

  M. Hilvo;A. Innocenti;S. M. Monti;G. D. Simone;C. T. Supuran;S. Parkkila (2008). Recent advances in research on the most novel carbonic anhydrases, CA XIII and XV.. CURRENT PHARMACEUTICAL DESIGN, vol. 14, pp. 672-678, ISSN:1381-6128

  C. T. Supuran (2008). Diuretics: from classical carbonic anhydrase inhibitors to novel applications of the sulfonamides.. CURRENT PHARMACEUTICAL DESIGN, vol. 14, pp. 641-648, ISSN:1381-6128

  J. Winum;A. Scozzafava;J. Montero;C. T. Supuran (2008). Design of zinc binding functions for carbonic anhydrase inhibitors.. CURRENT PHARMACEUTICAL DESIGN, vol. 14, pp. 615-621, ISSN:1381-6128

  S. Morishita;I. Nishimori;T. Minakuchi;S. Onishi;H. Takeuchi;T. Sugiura;D. Vullo;A. Scozzafava;C. T. Supuran (2008). Cloning, polymorphism, and inhibition of beta-carbonic anhydrase of Helicobacter pylori.. JOURNAL OF GASTROENTEROLOGY, vol. 43, pp. 849-857, ISSN:0944-1174 DOI   Accesso ONLINE all'editore

  A. Innocenti;M. Hilvo;A. Scozzafava;M. Lindfors;H. R. Nordlund;M. S. Kulomaa;S. Parkkila;C. T. Supuran (2008). Carbonic anhydrase inhibitors: the very weak inhibitors dithiothreitol, beta-mercaptoethanol, tris(carboxyethyl)phosphine and threitol interfere with the binding of sulfonamides to isozymes II and IX.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 1898-1903, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  C. T. Supuran;A. D. Fiore;G. D. Simone (2008). Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity.. EXPERT OPINION ON EMERGING DRUGS, vol. 13, pp. 383-392, ISSN:1472-8214 DOI   Accesso ONLINE all'editore

  Claudiu T. Supuran (2008). Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. NATURE REVIEWS DRUG DISCOVERY, vol. 7, pp. 168-181, ISSN:1474-1776 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Scozzafava;C. T. Supuran (2008). Carbonic anhydrase activation and the drug design.. CURRENT PHARMACEUTICAL DESIGN, vol. 14, pp. 708-715, ISSN:1381-6128

  A. Thiry;J. Dogné;C. T. Supuran;B. Masereel (2008). Anticonvulsant sulfonamides/sulfamates/sulfamides with carbonic anhydrase inhibitory activity: drug design and mechanism of action.. CURRENT PHARMACEUTICAL DESIGN, vol. 14, pp. 661-671, ISSN:1381-6128

  P. Swietach;S. Wigfield;P. Cobden;C. T. Supuran;A. L. Harris;R. D. Vaughan-Jones (2008). Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 283, pp. 20473-20483, ISSN:0021-9258 DOI   Accesso ONLINE all'editore

  S. M. Marques;E. Nuti;A. Rossello;C. T. Supuran;T. Tuccinardi;A. Martinelli;M. A. Santos (2008). Dual inhibitors of matrix metalloproteinases and carbonic anhydrases: iminodiacetyl-based hydroxamate-benzenesulfonamide conjugates.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 51, pp. 7968-7979, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  D. Vullo;I. Nishimori;A. Scozzafava;C. T. Supuran (2008). Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 4303-4307, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  F. Smaine;F. Pacchiano;M. Rami;V. Barragan-Montero;D. Vullo;A. Scozzafava;J. Winum;C. T. Supuran (2008). Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 6332-6335, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  A. Cecchi; L. Ciani; J.Y. Winum; J.L. Montero; A. Scozzafava; S. Ristori; C.T. Supuran (2008). Carbonic anhydrase inhibitors: Design of spin-labeled sulfonamides incorporating TEMPO moieties as probes for cytosolic or transmembrane isozymes. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, pp. 3475-3480, ISSN:0960-894X DOI  

  A. Innocenti;A. Maresca;A. Scozzafava;C. T. Supuran (2008). Carbonic anhydrase inhibitors: thioxolone versus sulfonamides for obtaining isozyme-selective inhibitors?. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 3938-3941, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  F. Mincione;A. Scozzafava;C. T. Supuran (2008). The development of topically acting carbonic anhydrase inhibitors as antiglaucoma agents.. CURRENT PHARMACEUTICAL DESIGN, vol. 14, pp. 649-654, ISSN:1381-6128

  M. P. Leese;F. L. Jourdan;K. Gaukroger;M. F. Mahon;S. P. Newman;P. A. Foster;C. Stengel;S. Regis-Lydi;E. Ferrandis;A. D. Fiore;G. D. Simone;C. T. Supuran;A. Purohit;M. J. Reed;B. V. L (2008). Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 51, pp. 1295-1308, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  R. A. Hall;D. Vullo;A. Innocenti;A. Scozzafava;C. T. Supuran;P. Klappa;F. A. Mühlschlegel (2008). External pH influences the transcriptional profile of the carbonic anhydrase, CAH-4b in Caenorhabditis elegans.. MOLECULAR AND BIOCHEMICAL PARASITOLOGY, vol. 161, pp. 140-149, ISSN:0166-6851 DOI   Accesso ONLINE all'editore

  C. T. Supuran (2008). Antiepileptic activity of zonisamide on hippocampal CA3 neurons does not depend on carbonic anhydrase inhibition.. EPILEPSY RESEARCH, vol. 82, pp. 109-109, ISSN:0920-1211 DOI   Accesso ONLINE all'editore

  J. Krungkrai;C. T. Supuran (2008). The alpha-carbonic anhydrase from the malaria parasite and its inhibition.. CURRENT PHARMACEUTICAL DESIGN, vol. 14, pp. 631-640, ISSN:1381-6128

  I. Nishimori;S. Onishi;H. Takeuchi;C. T. Supuran (2008). The alpha and beta classes carbonic anhydrases from Helicobacter pylori as novel drug targets.. CURRENT PHARMACEUTICAL DESIGN, vol. 14, pp. 622-630, ISSN:1381-6128

  C. T. Supuran (2008). Carbonic anhydrases as drug targets.. CURRENT PHARMACEUTICAL DESIGN, vol. 14, pp. 601-602, ISSN:1381-6128

  J. Krungkrai;S. R. Krungkrai;C. T. Supuran (2008). Carbonic anhydrase inhibitors: inhibition of Plasmodium falciparum carbonic anhydrase with aromatic/heterocyclic sulfonamides-in vitro and in vivo studies.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 5466-5471, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  B. L. Wilkinson;A. Innocenti;D. Vullo;C. T. Supuran;S. Poulsen (2008). Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 51, pp. 1945-1953, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  A. Thiry;S. Rolin;D. Vullo;A. Frankart;A. Scozzafava;J. Dogné;J. Wouters;C. T. Supuran;B. Masereel (2008). Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 43, pp. 2853-2860, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  S. Poulsen;B. L. Wilkinson;A. Innocenti;D. Vullo;C. T. Supuran (2008). Inhibition of human mitochondrial carbonic anhydrases VA and VB with para-(4-phenyltriazole-1-yl)-benzenesulfonamide derivatives.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 4624-4627, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  C. T. Supuran (2008). Carbonic anhydrases--an overview.. CURRENT PHARMACEUTICAL DESIGN, vol. 14, pp. 603-614, ISSN:1381-6128

  E. Bayram;M. Senturk;O. I. Kufrevioglu;C. T. Supuran (2008). In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 16, pp. 9101-9105, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  K. D'Ambrosio;B. Masereel;A. Thiry;A. Scozzafava;C. T. Supuran;G. D. Simone (2008). Carbonic anhydrase inhibitors: binding of indanesulfonamides to the human isoform II.. CHEMMEDCHEM, vol. 3, pp. 473-477, ISSN:1860-7179 DOI   Accesso ONLINE all'editore

  A. Innocenti;S. A. Zimmerman;A. Scozzafava;J. G. Ferry;C. T. Supuran (2008). Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 6194-6198, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  O. Güzel;A. Innocenti;A. Scozzafava;A. Salman;S. Parkkila;M. Hilvo;C. T. Supuran (2008). Carbonic anhydrase inhibitors: synthesis and inhibition studies against mammalian isoforms I-XV with a series of 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 16, pp. 9113-9120, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  A. Innocenti;F. A. Mühlschlegel;R. A. Hall;C. Steegborn; A. Scozzafava;C. T. Supuran (2008). Carbonic anhydrase inhibitors: inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with simple anions.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 5066-5070, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  M. Hilvo;L. Baranauskiene;A. M. Salzano;A. Scaloni;D. Matulis;A. Innocenti;A. Scozzafava;S. M. Monti;A. D. Fiore;G. D. Simone;M. Lindfors;J. Jänis;J. Valjakka;S. Pastoreková;J. Pastorek;M. S. Kulomaa;H. R. Nordlund;C. T. Supuran;S. Parkkila (2008). Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 283, pp. 27799-27809, ISSN:0021-9258 DOI   Accesso ONLINE all'editore

  K. D'Ambrosio;R. Vitale;J. Dogné;B. Masereel;A. Innocenti;A. Scozzafava;G. D. Simone;C. T. Supuran (2008). Carbonic anhydrase inhibitors: bioreductive nitro-containing sulfonamides with selectivity for targeting the tumor associated isoforms IX and XII.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 51, pp. 3230-3237, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  F. Saczewski;A. Innocenti;J. Sławiński;A. Kornicka;Z. Brzozowski;E. Pomarnacka;A. Scozzafava;C. Temperini;C. T. Supuran (2008). Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 16, pp. 3933-3940, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  A. Innocenti;D. Vullo;A. Scozzafava;C. T. Supuran (2008). Carbonic anhydrase inhibitors: interactions of phenols with the 12 catalytically active mammalian isoforms (CA I-XIV).. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 1583-1587, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  A. D. Fiore;C. Pedone;J. Antel;H. Waldeck;A. Witte;M. Wurl;A. Scozzafava;C. T. Supuran;G. D. Simone (2008). Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 2669-2674, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  A. Innocenti;A. Scozzafava;S. Parkkila;L. Puccetti;G. D. Simone;C. T. Supuran (2008). Investigations of the esterase, phosphatase, and sulfatase activities of the cytosolic mammalian carbonic anhydrase isoforms I, II, and XIII with 4-nitrophenyl esters as substrates.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 2267-2271, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  A. Innocenti;M. Hilvo;A. Scozzafava;S. Parkkila;C. T. Supuran (2008). Carbonic anhydrase inhibitors: Inhibition of the new membrane-associated isoform XV with phenols.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 3593-3596, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Innocenti;A. Scozzafava;C. T. Supuran (2008). Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 16, pp. 8373-8378, ISSN:1464-3391 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Innocenti;A. Scozzafava;C. T. Supuran (2008). Carbonic anhydrase inhibitors. Interaction of the antitumor sulfamate EMD 486019 with twelve mammalian carbonic anhydrase isoforms: Kinetic and X-ray crystallographic studies.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 4282-4286, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Cecchi;A. Scozzafava;C. T. Supuran (2008). Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct.. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 18, pp. 2567-2573, ISSN:1464-3405 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Cecchi;A. Scozzafava;C. T. Supuran (2008). Carbonic anhydrase inhibitors. Sulfonamide diuretics revisited--old leads for new applications?. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 6, pp. 2499-2506, ISSN:1477-0520 DOI   Accesso ONLINE all'editore

  M. Stiti;A. Cecchi;M. Rami;M. Abdaoui;V. Barragan-Montero;A. Scozzafava;Y. Guari;J. Winum;C. T. Supuran (2008). Carbonic anhydrase inhibitor coated gold nanoparticles selectively inhibit the tumor-associated isoform IX over the cytosolic isozymes I and II.. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 130, pp. 16130-16131, ISSN:0002-7863 DOI   Accesso ONLINE all'editore

  J. Winum;A. Thiry;K. E. Cheikh;J. Dogné;J. Montero;D. Vullo;A. Scozzafava;B. Masereel;C. T. Supuran (2007). Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose-thioureido tails.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 2685-2691, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  J. Winum;A. Scozzafava;J. Montero;C. T. Supuran (2007). Metal binding functions in the design of carbonic anhydrase inhibitors.. CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol. 7, pp. 835-848, ISSN:1568-0266

  A. Mastrolorenzo; C.T. Supuran; G. Zuccati (2007). The sexually trasmitted papillomavirus infections: clinical manifestations, current and future therapies. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 17, pp. 173-211, ISSN:1354-3776

  A. D. Fiore;A. Scozzafava;J. Winum;J. Montero;C. Pedone;C. T. Supuran;G. D. Simone (2007). Carbonic anhydrase inhibitors: binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 1726-1731, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  B. L. Wilkinson;L. F. Bornaghi;T. A. Houston;A. Innocenti;D. Vullo;C. T. Supuran;S. Poulsen (2007). Inhibition of membrane-associated carbonic anhydrase isozymes IX, XII and XIV with a library of glycoconjugate benzenesulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 987-992, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Thiry;J. Dogné;C. T. Supuran;B. Masereel (2007). Carbonic anhydrase inhibitors as anticonvulsant agents.. CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol. 7, pp. 855-864, ISSN:0973-0532

  T. Tuccinardi;E. Nuti;G. Ortore;C. T. Supuran;A. Rossello;A. Martinelli (2007). Analysis of human carbonic anhydrase II: docking reliability and receptor-based 3D-QSAR study.. JOURNAL OF CHEMICAL INFORMATION AND MODELING, vol. 47, pp. 515-525, ISSN:1549-960X DOI   Accesso ONLINE all'editore

  I. Nishimori;A. Innocenti;D. Vullo;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase inhibitors. Inhibition studies of the human secretory isoform VI with anions.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 1037-1042, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  F. Smaine;J. Winum;J. Montero;Z. Regainia;D. Vullo;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase inhibitors: Selective inhibition of the extracellular, tumor-associated isoforms IX and XII over isozymes I and II with glycosyl-thioureido-sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 5096-5100, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  I. Nishimori;T. Minakuchi;S. Onishi;D. Vullo;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 50, pp. 381-388, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  A. Innocenti;D. Vullo;J. Pastorek;A. Scozzafava;S. Pastorekova;I. Nishimori;C. T. Supuran (2007). Carbonic anhydrase inhibitors. Inhibition of transmembrane isozymes XII (cancer-associated) and XIV with anions.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 1532-1537, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  M. Hilvo;C. T. Supuran;S. Parkkila (2007). Characterization and inhibition of the recently discovered carbonic anhydrase isoforms CA XIII, XIV and XV.. CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol. 7, pp. 893-899, ISSN:0973-0532

  C. T. Supuran (2007). Carbonic anhydrases as drug targets--an overview.. CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol. 7, pp. 825-833, ISSN:0973-0532

  B. L. Wilkinson;L. F. Bornaghi;T. A. Houston;A. Innocenti;D. Vullo;C. T. Supuran;S. Poulsen (2007). Carbonic anhydrase inhibitors: inhibition of isozymes I, II, and IX with triazole-linked O-glycosides of benzene sulfonamides.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 50, pp. 1651-1657, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  G. D. Simone;C. T. Supuran (2007). Antiobesity carbonic anhydrase inhibitors.. CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol. 7, pp. 879-884, ISSN:1568-0266

  J. Singh;B. Shaik;S. Singh;S. Sikhima;V. K. Agrawal;P. V. Khadikar;C. T. Supuran (2007). QSAR studies on the activation of the human carbonic anhydrase cytosolic isoforms I and II and secretory isozyme VI with amino acids and amines.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 15, pp. 6501-6509, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  A. Casini; G. Mastrobuoni; A. Temperini; C. Gabbiani; S. Francese; G. Moneti; C.T. Supuran; A. Scozzafava; L. Messori (2007). ESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme. CHEMICAL COMMUNICATIONS, vol. 2, pp. 156-158, ISSN:1359-7345 DOI  

  P. A. Colinas;R. D. Bravo;D. Vullo;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I and II, and extracellular isoforms IV, IX, and XII with sulfamides incorporating sugar moieties.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 5086-5090, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  R. Riihonen;C. T. Supuran;S. Parkkila;S. Pastorekova;H. K. Väänänen;T. Laitala-Leinonen (2007). Membrane-bound carbonic anhydrases in osteoclasts.. BONE, vol. 40, pp. 1021-1031, ISSN:8756-3282 DOI   Accesso ONLINE all'editore

  L. Tarko;C. T. Supuran (2007). QSAR studies for the inhibition of the transmembrane isozymes XII and XIV of human carbonic anhydrase with a series of sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 15, pp. 5666-5671, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  I. Nishimori;A. Innocenti;D. Vullo;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase inhibitors: the inhibition profiles of the human mitochondrial isoforms VA and VB with anions are very different.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 15, pp. 6742-6747, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  I. Nishimori;T. Minakuchi;T. Kohsaki;S. Onishi;H. Takeuchi;D. Vullo;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 3585-3594, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  C. Temperini;A. Innocenti;A. Guerri;A. Scozzafava;S. Rusconi;C. T. Supuran (2007). Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 2210-2215, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  M. K. Abdel-Hamid;A. A. Abdel-Hafez;N. A. El-Koussi;N. M. Mahfouz;A. Innocenti;C. T. Supuran (2007). Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 15, pp. 6975-6984, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Innocenti;A. Mastrolorenzo;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: kinetic and X-ray crystallographic studies.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 4866-4872, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  E. Nuti;E. Orlandini;S. Nencetti;A. Rossello;A. Innocenti;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 15, pp. 2298-2311, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  M. Zareef;R. Iqbal;N. G. De;J. Rodrigues;J. H. Zaidi;M. Arfan;C. T. Supuran (2007). Synthesis and antimalarial activity of novel chiral and achiral benzenesulfonamides bearing 1, 3, 4-oxadiazole moieties.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 22, pp. 301-308, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  A. Thiry;B. Masereel;J. Dogné;C. T. Supuran;J. Wouters;C. Michaux (2007). Exploration of the binding mode of indanesulfonamides as selective inhibitors of human carbonic anhydrase type VII by targeting Lys 91.. CHEMMEDCHEM, vol. 2, pp. 1273-1280, ISSN:1860-7179 DOI   Accesso ONLINE all'editore

  A. Ohradanova;D. Vullo;J. Kopacek;C. Temperini;T. Betakova;S. Pastorekova;J. Pastorek;C. T. Supuran (2007). Reconstitution of carbonic anhydrase activity of the cell-surface-binding protein of vaccinia virus.. BIOCHEMICAL JOURNAL, vol. 407, pp. 61-67, ISSN:0264-6021 DOI   Accesso ONLINE all'editore

  S. A. Zimmerman;J. G. Ferry;C. T. Supuran (2007). Inhibition of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases.. CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol. 7, pp. 901-908, ISSN:0973-0532

  A. J. Salmon;M. L. Williams;A. Innocenti;D. Vullo;C. T. Supuran;S. Poulsen (2007). Inhibition of carbonic anhydrase isozymes I, II and IX with benzenesulfonamides containing an organometallic moiety.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 5032-5035, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  I. Nishimori;S. Onishi;D. Vullo;A. Innocenti;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 15, pp. 5351-5357, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  J. Krungkrai;S. R. Krungkrai;C. T. Supuran (2007). Malarial parasite carbonic anhydrase and its inhibitors.. CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol. 7, pp. 909-917, ISSN:1568-0266

  D. Vullo;I. Nishimori;A. Innocenti;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase activators: an activation study of the human mitochondrial isoforms VA and VB with amino acids and amines.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 1336-1340, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  I. Nishimori;T. Minakuchi;S. Onishi;D. Vullo;A. Cecchi;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 15, pp. 7229-7236, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  L. Dubois;K. Douma;C. T. Supuran;R. K. Chiu;M. A. M J van Zandvoort;S. Pastoreková;A. Scozzafava;B. G. Wouters;P. Lambin (2007). Imaging the hypoxia surrogate marker CA IX requires expression and catalytic activity for binding fluorescent sulfonamide inhibitors.. RADIOTHERAPY AND ONCOLOGY, vol. 83, pp. 367-373, ISSN:0167-8140 DOI   Accesso ONLINE all'editore

  J. Dogné;A. Thiry;D. Pratico;B. Masereel;C. T. Supuran (2007). Dual carbonic anhydrase--cyclooxygenase-2 inhibitors.. CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol. 7, pp. 885-891, ISSN:0973-0532

  T. Tuccinardi;G. Ortore;A. Rossello;C. T. Supuran;A. Martinelli (2007). Homology modeling and receptor-based 3D-QSAR study of carbonic anhydrase IX.. JOURNAL OF CHEMICAL INFORMATION AND MODELING, vol. 47, pp. 2253-2262, ISSN:1549-960X DOI   Accesso ONLINE all'editore

  V. Alterio;G. D. Simone;S. M. Monti;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase inhibitors: inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides--solution and crystallographic studies.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 4201-4207, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  C. Temperini;J. Winum;J. Montero;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase inhibitors: the X-ray crystal structure of the adduct of N-hydroxysulfamide with isozyme II explains why this new zinc binding function is effective in the design of potent inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 2795-2801, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Mastrolorenzo;S. Rusconi;A. Scozzafava;G. Barbaro;C. T. Supuran (2007). Inhibitors of HIV-1 protease: current state of the art 10 years after their introduction. From antiretroviral drugs to antifungal, antibacterial and antitumor agents based on aspartic protease inhibitors.. CURRENT MEDICINAL CHEMISTRY, vol. 14, pp. 2734-2748, ISSN:0929-8673

  S. Rusconi;A. Scozzafava;A. Mastrolorenzo;C. T. Supuran (2007). An update in the development of HIV entry inhibitors.. CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol. 7, pp. 1273-1289, ISSN:1568-0266

  C. T. Supuran;A. Scozzafava (2007). Carbonic anhydrases as targets for medicinal chemistry.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 15, pp. 4336-4350, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  K. Köhler;A. Hillebrecht;J. S. Wischeler;A. Innocenti;A. Heine;C. T. Supuran;G. Klebe (2007). Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste.. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 46, pp. 7697-7699, ISSN:1433-7851 DOI   Accesso ONLINE all'editore

  D. Vullo;A. Innocenti;I. Nishimori;A. Scozzafava;K. Kaila;C. T. Supuran (2007). Carbonic anhydrase activators: activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 4107-4112, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  R. M. Vitale;C. Pedone;P. Amodeo;J. Antel;M. Wurl;A. Scozzafava;C. T. Supuran;G. D. Simone (2007). Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 15, pp. 4152-4158, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Innocenti;A. Scozzafava;A. Mastrolorenzo;C. T. Supuran (2007). Carbonic anhydrase activators: L-Adrenaline plugs the active site entrance of isozyme II, activating better isoforms I, IV, VA, VII, and XIV.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 628-635, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  M. A. Santos;S. Marques;D. Vullo;A. Innocenti;A. Scozzafava;C. T. Supuran (2007). Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated isoforms I, II, and IX with iminodiacetic carboxylates/hydroxamates also incorporating benzenesulfonamide moieties.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 17, pp. 1538-1543, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  M. Mizumori;J. Meyerowitz;T. Takeuchi;S. Lim;P. Lee;C. T. Supuran;P. H. Guth;E. Engel;J. D. Kaunitz;Y. Akiba (2006). Epithelial carbonic anhydrases facilitate PCO2 and pH regulation in rat duodenal mucosa.. THE JOURNAL OF PHYSIOLOGY, vol. 573, pp. 827-842, ISSN:0022-3751 DOI   Accesso ONLINE all'editore

  J. Winum;A. Scozzafava;J. Montero;C. T. Supuran (2006). Therapeutic potential of sulfamides as enzyme inhibitors.. MEDICINAL RESEARCH REVIEWS, vol. 26, pp. 767-792, ISSN:0198-6325 DOI   Accesso ONLINE all'editore

  V. Alterio;R. M. Vitale;S. M. Monti;C. Pedone;A. Scozzafava;A. Cecchi;G. D. Simone;C. T. Supuran (2006). Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX.. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 128, pp. 8329-8335, ISSN:0002-7863 DOI   Accesso ONLINE all'editore

  D. Vullo;B. Steffansen;B. Brodin;C. T. Supuran;A. Scozzafava;C. U. Nielsen (2006). Carbonic anhydrase inhibitors: transepithelial transport of thioureido sulfonamide inhibitors of the cancer-associated isozyme IX is dependent on efflux transporters.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 14, pp. 2418-2427, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  J. Winum;C. Temperini;K. E. Cheikh;A. Innocenti;D. Vullo;S. Ciattini;J. Montero;A. Scozzafava;C. T. Supuran (2006). Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, pp. 7024-7031, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  I. Nishimori;D. Vullo;T. Minakuchi;K. Morimoto;S. Onishi;A. Scozzafava;C. T. Supuran (2006). Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 16, pp. 2182-2188, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Weber;M. Böhm;C. T. Supuran;A. Scozzafava;C. A. Sotriffer;G. Klebe (2006). 3D QSAR selectivity analyses of carbonic anhydrase inhibitors: insights for the design of isozyme selective inhibitors.. JOURNAL OF CHEMICAL INFORMATION AND MODELING, vol. 46, pp. 2737-2760, ISSN:1549-9596 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;M. Arif;Z. Shafiq;M. Yaqub;C. T. Supuran (2006). In vitro antibacterial, antifungal & cytotoxic activity of some isonicotinoylhydrazide Schiff's bases and their cobalt (II), copper (II), nickel (II) and zinc (II) complexes.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 21, pp. 95-103, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  V. K. Agrawal;J. Singh;M. Gupta;Y. A. Jaliwala;P. V. Khadikar;C. T. Supuran (2006). QSAR studies on benzopyran potassium channel activators.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 41, pp. 360-366, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;C. T. Supuran (2006). Metalloantibiotics: synthesis, characterization and in-vitro antibacterial studies on cobalt (II), copper (II), nickel (II) and zinc (II) complexes with cloxacillin.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 21, pp. 441-448, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;A. Rauf;M. M. Naseer;M. A. Somra;C. T. Supuran (2006). Antibacterial, antifungal and cytotoxic properties of some sulfonamide-derived chromones.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 21, pp. 173-177, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  G. Melagraki;A. Afantitis;H. Sarimveis;O. Igglessi-Markopoulou;C. T. Supuran (2006). QSAR study on para-substituted aromatic sulfonamides as carbonic anhydrase II inhibitors using topological information indices.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 14, pp. 1108-1114, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  A. Thiry;M. Ledecq;A. Cecchi;J. Dogné;J. Wouters;C. T. Supuran;B. Masereel (2006). Indanesulfonamides as carbonic anhydrase inhibitors. Toward structure-based design of selective inhibitors of the tumor-associated isozyme CA IX.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, pp. 2743-2749, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Z. T. Maqsood;K. M. Khan;U. Ashiq;R. A. Jamal;Z. H. Chohan;M. Mahroof-Tahir;C. T. Supuran (2006). Oxovanadium(IV) complexes of hydrazides: potential antifungal agents.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 21, pp. 37-42, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  O. Ozensoy;F. Kockar;O. Arslan;S. Isik;C. T. Supuran;M. Lyon (2006). An evaluation of cytosolic erythrocyte carbonic anhydrase and catalase in carcinoma patients: an elevation of carbonic anhydrase activity.. CLINICAL BIOCHEMISTRY, vol. 39, pp. 804-809, ISSN:0009-9120 DOI   Accesso ONLINE all'editore

  J. Winum;A. Scozzafava;J. Montero;C. T. Supuran (2006). The sulfamide motif in the design of enzyme inhibitors.. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 16, pp. 27-47, ISSN:1354-3776 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;M. Arif;M. A. Akhtar;C. T. Supuran (2006). Metal-Based Antibacterial and Antifungal Agents: Synthesis, Characterization, and In Vitro Biological Evaluation of Co(II), Cu(II), Ni(II), and Zn(II) Complexes With Amino Acid-Derived Compounds.. BIOINORGANIC CHEMISTRY AND APPLICATIONS, pp. 83131-83144, ISSN:1565-3633 DOI   Accesso ONLINE all'editore

  V. Menchise;G. D. Simone;A. D. Fiore;A. Scozzafava;C. T. Supuran (2006). Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1,3,4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide to human isoform II.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 16, pp. 6204-6208, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  F. Saczewski;J. Sławiński;A. Kornicka;Z. Brzozowski;E. Pomarnacka;A. Innocenti;A. Scozzafava;C. T. Supuran (2006). Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 16, pp. 4846-4851, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  J. Winum;A. Scozzafava;J. Montero;C. T. Supuran (2006). New zinc binding motifs in the design of selective carbonic anhydrase inhibitors.. MINI-REVIEWS IN MEDICINAL CHEMISTRY, vol. 6, pp. 921-936, ISSN:1389-5575

  A. Hillebrecht;C. T. Supuran;G. Klebe (2006). Integrated approach using protein and ligand information to analyze selectivity- and affinity-determining features of carbonic anhydrase isozymes.. CHEMMEDCHEM, vol. 1, pp. 839-853, ISSN:1860-7179 DOI   Accesso ONLINE all'editore

  B. L. Wilkinson;L. F. Bornaghi;T. A. Houston;A. Innocenti;C. T. Supuran;S. Poulsen (2006). A novel class of carbonic anhydrase inhibitors: glycoconjugate benzene sulfonamides prepared by "click-tailing".. JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, pp. 6539-6548, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  C. T. Supuran;A. Mastrolorenzo;G. Barbaro;A. Scozzafava (2006). Phosphodiesterase 5 inhibitors--drug design and differentiation based on selectivity, pharmacokinetic and efficacy profiles.. CURRENT PHARMACEUTICAL DESIGN, vol. 12, pp. 3459-3465, ISSN:1381-6128

  M. P. Leese;B. Leblond;A. Smith;S. P. Newman;A. D. Fiore;G. D. Simone;C. T. Supuran;A. Purohit;M. J. Reed;B. V. L (2006). 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, pp. 7683-7696, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;A. U. Shaikh;M. M. Naseer;C. T. Supuran (2006). In-vitro antibacterial, antifungal and cytotoxic properties of metal-based furanyl derived sulfonamides.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 21, pp. 771-781, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  D. Vullo;E. Ruusuvuori;K. Kaila;A. Scozzafava;C. T. Supuran (2006). Carbonic anhydrase inhibitors: inhibition of the cytosolic human isozyme VII with anions.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 16, pp. 3139-3143, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  I. Nishimori;T. Minakuchi;K. Morimoto;S. Sano;S. Onishi;H. Takeuchi;D. Vullo;A. Scozzafava;C. T. Supuran (2006). Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, pp. 2117-2126, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  J. Winum;A. Cecchi;A. Seridi;A. Scozzafava;J. Montero;C. T. Supuran (2006). Carbonic anhydrase inhibitors. N-cyanomethylsulfonamides--a new zinc binding group in the design of inhibitors targeting cytosolic and membrane-anchored isoforms.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 21, pp. 477-481, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  B. W. Clare;C. T. Supuran (2006). A perspective on quantitative structure-activity relationships and carbonic anhydrase inhibitors.. EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, vol. 2, pp. 113-137, ISSN:1742-5255 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;A. U. Shaikh;A. Rauf;C. T. Supuran (2006). Antibacterial, antifungal and cytotoxic properties of novel N-substituted sulfonamides from 4-hydroxycoumarin.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 21, pp. 741-748, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Scozzafava;D. Vullo;C. T. Supuran (2006). Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: stereospecific recognition within the active site of an enzyme and its consequences for the drug design.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, pp. 3019-3027, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  A. Mastrolorenzo;L. Tiradritti;F. Vichi;S. Ketabchi;C. T. Supuran;G. Zuccati (2006). Primary anetoderma and HIV infection: a case report.. THE AIDS READER, vol. 16, pp. 92-6; discussion 94-5, ISSN:1053-0894

  V. K. Agrawal;J. Singh;P. V. Khadikar;C. T. Supuran (2006). QSAR study on topically acting sulfonamides incorporating GABA moieties: a molecular connectivity approach.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 16, pp. 2044-2051, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Thiry;J. Dogné;B. Masereel;C. T. Supuran (2006). Targeting tumor-associated carbonic anhydrase IX in cancer therapy.. TRENDS IN PHARMACOLOGICAL SCIENCES, vol. 27, pp. 566-573, ISSN:0165-6147 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;H. Pervez;A. Rauf;K. M. Khan;C. T. Supuran (2006). Antibacterial cobalt (II), copper (II), nickel (II) and zinc (II) complexes of mercaptothiadiazole--derived furanyl, thienyl, pyrrolyl, salicylyl and pyridinyl Schiff bases.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 21, pp. 193-201, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  S. Parkkila;D. Vullo;L. Puccetti;A. Parkkila;A. Scozzafava;C. T. Supuran (2006). Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 16, pp. 3955-3959, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Lisa Simi; Giulia Venturini; Francesca Malentacchi; Stefania Gelmini; Matteo Andreani; Alberto Janni; Silvia Pastorekova; Claudiu T Supuran; Mario Pazzagli; Claudio Orlando (2006). Quantitative analysis of carbonic anhydrase IX mRNA in human non-small cell lung cancer.. LUNG CANCER, vol. 52, pp. 59-66, ISSN:0169-5002

  A. D. Fiore;C. Pedone;K. D'Ambrosio;A. Scozzafava;G. D. Simone;C. T. Supuran (2006). Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 16, pp. 437-442, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  F. Saczewski;A. Innocenti;Z. Brzozowski;J. Slawiński;E. Pomarnacka;A. Kornicka;A. Scozzafava;C. T. Supuran (2006). Carbonic anhydrase inhibitors. Selective inhibition of human tumor-associated isozymes IX and XII and cytosolic isozymes I and II with some substituted-2-mercapto-benzenesulfonamides.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 21, pp. 563-568, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  G. D. Simone;R. M. Vitale;A. D. Fiore;C. Pedone;A. Scozzafava;J. Montero;J. Winum;C. T. Supuran (2006). Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, pp. 5544-5551, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  M. Zareef;A. Innocenti;R. Iqbal;J. H. Zaidi;M. Arfan;A. Scozzafava;C. T. Supuran (2006). Carbonic anhydrase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozymes I and II with some 1,3,4-oxadiazole-thiols.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 21, pp. 351-359, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Scozzafava;C. T. Supuran (2006). Carbonic anhydrase activators: the first X-ray crystallographic study of an adduct of isoform I.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 16, pp. 5152-5156, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  V. Endeward;R. Musa-Aziz;G. J. Cooper;L. Chen;M. F. Pelletier;L. V. Virkki;C. T. Supuran;L. S. King;W. F. Boron;G. Gros (2006). Evidence that aquaporin 1 is a major pathway for CO2 transport across the human erythrocyte membrane.. THE FASEB JOURNAL, vol. 20, pp. 1974-1981, ISSN:0892-6638 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;A. U. Shaikh;C. T. Supuran (2006). In-vitro antibacterial, antifungal and cytotoxic activity of cobalt (II), copper (II), nickel (II) and zinc (II) complexes with furanylmethyl- and thienylmethyl-dithiolenes: [1, 3-dithiole- 2-one and 1,3-dithiole-2-thione].. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 21, pp. 733-740, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Scozzafava;D. Vullo;C. T. Supuran (2006). Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII, and XIV with l- and d-histidine and crystallographic analysis of their adducts with isoform II: engineering proton-transfer processes within the active site of an enzyme.. CHEMISTRY-A EUROPEAN JOURNAL, vol. 12, pp. 7057-7066, ISSN:0947-6539 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Innocenti;A. Scozzafava;C. T. Supuran (2006). N-hydroxyurea--a versatile zinc binding function in the design of metalloenzyme inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 16, pp. 4316-4320, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  S. U. Rehman;Z. H. Chohan;F. Gulnaz;C. T. Supuran (2005). In-vitro antibacterial, antifungal and cytotoxic activities of some coumarins and their metal complexes.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 20, pp. 333-340, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  O. Ozensoy;S. Isik;O. Arslan;M. Arslan;A. Scozzafava;C. T. Supuran (2005). Carbonic anhydrase inhibitors. Inhibition of red blood cell ostrich (Struthio camelus) carbonic anhydrase with a series of aromatic and heterocyclic sulfonamides.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 20, pp. 383-387, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  A. D. Fiore;G. D. Simone;V. Menchise;C. Pedone;A. Casini;A. Scozzafava;C. T. Supuran (2005). Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 1937-1942, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  D. Vullo;J. Voipio;A. Innocenti;C. Rivera;H. Ranki;A. Scozzafava;K. Kaila;C. T. Supuran (2005). Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 971-976, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  P. V. Khadikar;V. Sharma;S. Karmarkar;C. T. Supuran (2005). Novel use of chemical shift in NMR as molecular descriptor: a first report on modeling carbonic anhydrase inhibitory activity and related parameters.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 931-936, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  M. Thakur;A. Thakur;P. V. Khadikar;C. T. Supuran (2005). QSAR study on pK(a) vis-à-vis physiological activity of sulfonamides: a dominating role of surface tension (inverse steric parameter).. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 203-209, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Cecchi;S. D. Taylor;Y. Liu;B. Hill;D. Vullo;A. Scozzafava;C. T. Supuran (2005). Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 5192-5196, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  H. Turkmen;M. Durgun;S. Yilmaztekin;M. Emul;A. Innocenti;D. Vullo;A. Scozzafava;C. T. Supuran (2005). Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 367-372, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Hasan;K. M. Khan;M. Sher;G. M. Maharvi;S. A. Nawaz;M. I. Choudhary;A. u. Rahman;C. T. Supuran (2005). Synthesis and inhibitory potential towards acetylcholinesterase, butyrylcholinesterase and lipoxygenase of some variably substituted chalcones.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 20, pp. 41-47, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  G. D. Simone;A. D. Fiore;V. Menchise;C. Pedone;J. Antel;A. Casini;A. Scozzafava;M. Wurl;C. T. Supuran (2005). Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 2315-2320, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  K. M. Khan;Z. S. Saify;M. T. H;N. Butt;G. M. Maharvi;S. Perveen;N. Ambreen;M. I. Choudhary;A. Ur-Rahman;C. T. Supuran (2005). Tyrosinase inhibition: conformational analysis based studies on molecular dynamics calculations of bipiperidine based inhibitors.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 20, pp. 401-407, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;M. Ul-Hassan;K. M. Khan;C. T. Supuran (2005). In-vitro antibacterial, antifungal and cytotoxic properties of sulfonamide--derived Schiff's bases and their metal complexes.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 20, pp. 183-188, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  B. W. Clare;C. T. Supuran (2005). Predictive flip regression: a technique for QSAR of derivatives of symmetric molecules.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 45, pp. 1385-1391, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  V. Garaj;L. Puccetti;G. Fasolis;J. Winum;J. Montero;A. Scozzafava;D. Vullo;A. Innocenti;C. T. Supuran (2005). Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 3102-3108, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Innocenti;M. A. Firnges;J. Antel;M. Wurl;A. Scozzafava;C. T. Supuran (2005). Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 1149-1154, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Innocenti;D. Vullo;A. Scozzafava;C. T. Supuran (2005). Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 567-571, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Cecchi;A. Hulikova;J. Pastorek;S. Pastoreková;A. Scozzafava;J. Winum;J. Montero;C. T. Supuran (2005). Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 48, pp. 4834-4841, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  A. T. Balaban;P. V. Khadikar;C. T. Supuran;A. Thakur;M. Thakur (2005). Study on supramolecular complexing ability vis-à-vis estimation of pKa of substituted sulfonamides: dominating role of Balaban index (J).. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 3966-3973, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  J. Winum;A. Innocenti;J. Nasr;J. Montero;A. Scozzafava;D. Vullo;C. T. Supuran (2005). Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with N-hydroxysulfamides--a new zinc-binding function in the design of inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 2353-2358, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  L. Puccetti;G. Fasolis;A. Cecchi;J. Winum;A. Gamberi;J. Montero;A. Scozzafava;C. T. Supuran (2005). Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 2359-2364, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  J. Krungkrai;A. Scozzafava;S. Reungprapavut;S. R. Krungkrai;R. Rattanajak;S. Kamchonwongpaisan;C. T. Supuran (2005). Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic sulfonamides: towards antimalarials with a novel mechanism of action?. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 13, pp. 483-489, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  V. K. Agrawal;M. Banerji;M. Gupta;J. Singh;P. V. Khadikar;C. T. Supuran (2005). QSAR study on carbonic anhydrase inhibitors: water-soluble sulfonamides incorporating beta-alanyl moieties, possessing long lasting-intra ocular pressure lowering properties--a molecular connectivity approach.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 40, pp. 1002-1012, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;H. Pervez;K. M. Khan;C. T. Supuran (2005). Organometallic-based antibacterial and antifungal compounds: transition metal complexes of 1,1'-diacetylferrocene-derived thiocarbohydrazone, carbohydrazone, thiosemicarbazone and semicarbazone.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 20, pp. 81-88, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  S. Pastorekova;D. Vullo;A. Casini;A. Scozzafava;J. Pastorek;I. Nishimori;C. T. Supuran (2005). Carbonic anhydrase inhibitors: Inhibition of the tumor-associated isozymes IX and XII with polyfluorinated aromatic/heterocyclic sulfonamides.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 20, pp. 211-217, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  J. Winum;A. Cecchi;J. Montero;A. Innocenti;A. Scozzafava;C. T. Supuran (2005). Carbonic anhydrase inhibitors. Synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with boron-containing sulfonamides, sulfamides, and sulfamates: toward agents for boron neutron capture therapy of hypoxic tumors.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 3302-3306, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  I. Nishimori;D. Vullo;A. Innocenti;A. Scozzafava;A. Mastrolorenzo;C. T. Supuran (2005). Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 48, pp. 7860-7866, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  V. Menchise;G. D. Simone;V. Alterio;A. D. Fiore;C. Pedone;A. Scozzafava;C. T. Supuran (2005). Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 48, pp. 5721-5727, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  L. Puccetti;G. Fasolis;D. Vullo;Z. H. Chohan;A. Scozzafava;C. T. Supuran (2005). Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 3096-3101, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Innocenti;R. Villar;V. Martinez-Merino;M. J. Gil;A. Scozzafava;D. Vullo;C. T. Supuran (2005). Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with benzo[b]thiophene 1,1-dioxide sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 4872-4876, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  I. Nishimori;D. Vullo;A. Innocenti;A. Scozzafava;A. Mastrolorenzo;C. T. Supuran (2005). Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 3828-3833, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  G. Barbaro;A. Scozzafava;A. Mastrolorenzo;C. T. Supuran (2005). Highly active antiretroviral therapy: current state of the art, new agents and their pharmacological interactions useful for improving therapeutic outcome.. CURRENT PHARMACEUTICAL DESIGN, vol. 11, pp. 1805-1843, ISSN:1381-6128

  O. Ozensoy;L. Puccetti;G. Fasolis;O. Arslan;A. Scozzafava;C. T. Supuran (2005). Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozymes IX and XII with a library of aromatic and heteroaromatic sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 4862-4866, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  F. Mincione;M. Starnotti;E. Masini;L. Bacciottini;C. Scrivanti;A. Casini;D. Vullo;A. Scozzafava;C. T. Supuran (2005). Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 3821-3827, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  J. Dogné;C. T. Supuran;D. Pratico (2005). Adverse cardiovascular effects of the coxibs.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 48, pp. 2251-2257, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  B. W. Clare;C. T. Supuran (2005). A physically interpretable quantum-theoretic QSAR for some carbonic anhydrase inhibitors with diverse aromatic rings, obtained by a new QSAR procedure.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 13, pp. 2197-2211, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  O. Hisar;S. Beydemir;I. Gülçin;O. I. Küfrevioğlu;C. T. Supuran (2005). Effects of low molecular weight plasma inhibitors of rainbow trout (Oncorhynchus mykiss) on human erythrocyte carbonic anhydrase-II isozyme activity in vitro and rat erythrocytes in vivo.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 20, pp. 35-39, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  J. Winum;A. Scozzafava;J. Montero;C. T. Supuran (2005). Sulfamates and their therapeutic potential.. MEDICINAL RESEARCH REVIEWS, vol. 25, pp. 186-228, ISSN:0198-6325 DOI   Accesso ONLINE all'editore

  D. Vullo;A. Innocenti;I. Nishimori;J. Pastorek;A. Scozzafava;S. Pastoreková;C. T. Supuran (2005). Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 963-969, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Dar;K. M. Khan;H. S. Ateeq;S. Khan;S. Rahat;S. Perveen;C. T. Supuran (2005). Inhibition of monoamine oxidase-A activity in rat brain by synthetic hydrazines: structure-activity relationship (SAR).. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 20, pp. 269-274, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  J. Winum;S. Pastorekova;L. Jakubickova;J. Montero;A. Scozzafava;J. Pastorek;D. Vullo;A. Innocenti;C. T. Supuran (2005). Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with bis-sulfamates.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 579-584, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  L. Puccetti;C. T. Supuran;P. P. Fasolo;E. Conti;G. Sebastiani;S. Lacquaniti;R. Mandras;M. G. Milazzo;N. Dogliani;P. D. Giuli;G. Fasolis (2005). Skewing towards neuroendocrine phenotype in high grade or high stage androgen-responsive primary prostate cancer.. EUROPEAN UROLOGY, vol. 48, pp. 215-21; Discussion 221-3, ISSN:0302-2838 DOI   Accesso ONLINE all'editore

  P. V. Khadikar;V. Sharma;S. Karmarkar;C. T. Supuran (2005). QSAR studies on benzene sulfonamide carbonic anhydrase inhibitors: need of hydrophobic parameter for topological modeling of binding constants of sulfonamides to human CA-II.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 923-930, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Z. H. Chohan;C. T. Supuran;A. Scozzafava (2005). Metal binding and antibacterial activity of ciprofloxacin complexes.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 20, pp. 303-307, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  C. Temperini;A. Scozzafava;L. Puccetti;C. T. Supuran (2005). Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with L-histidine as a platform for the design of stronger activators.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 5136-5141, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  O. Ozensoy;I. Nishimori;D. Vullo;L. Puccetti;A. Scozzafava;C. T. Supuran (2005). Carbonic anhydrase inhibitors: inhibition of the human transmembrane isozyme XIV with a library of aromatic/heterocyclic sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 13, pp. 6089-6093, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;C. T. Supuran (2005). In-vitro antibacterial and cytotoxic activity of cobalt (ii), copper (ii), nickel (ii) and zinc (ii) complexes of the antibiotic drug cephalothin (Keflin).. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 20, pp. 463-468, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  S. A. Tripodi;M. T. Del;C. T. Supuran;A. Scozzafava;M. G. Gabrielli;S. Pastorekova;R. Rossie;G. Fasolis;L. Puccetti (2004). Redox state and carbonic anhydrase isozyme IX expression in human renal cell carcinoma: biochemical and morphological investigations.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 19, pp. 287-291, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  D. Vullo;M. Franchi;E. Gallori;J. Antel;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors. Inhibition of mitochondrial isozyme V with aromatic and heterocyclic sulfonamides.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 47, pp. 1272-1279, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  A. INNOCENTI; A. CASINI; M.C. ALCARO; A.M. PAPINI; A. SCOZZAFAVA; C.T. SUPURAN (2004). Carbonic anhydrase inhibitors: The first on-resin screening of a 4-sulfamoylphenylthioureas library. JOURNAL OF MEDICINAL CHEMISTRY, vol. 47, pp. 5224-5229, ISSN:0022-2623 DOI  

  Z. H. Chohan;H. Pervez;K. M. Khan;A. Rauf;G. M. Maharvi;C. T. Supuran (2004). Antifungal cobalt(II), copper(II), nickel(II) and zinc(II) complexes of furanyl-,thiophenyl-, pyrrolyl-, salicylyl- and pyridyl-derived cephalexins.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 19, pp. 85-90, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  M. A. Ilies;B. Masereel;S. Rolin;A. Scozzafava;G. Câmpeanu;V. Cîmpeanu;C. T. Supuran (2004). Carbonic anhydrase inhibitors: aromatic and heterocyclic sulfonamides incorporating adamantyl moieties with strong anticonvulsant activity.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 12, pp. 2717-2726, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  K. M. Khan;Z. S. Saify;M. Z. Khan; Zia-Ullah;I. M. Choudhary;A. Ur-Rahman;S. Perveen;Z. H. Chohan;C. T. Supuran (2004). Synthesis of coumarin derivatives with cytotoxic, antibacterial and antifungal activity.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 19, pp. 373-379, ISSN:1475-6366

  M. Jaiswal;P. V. Khadikar;C. T. Supuran (2004). Topological modeling of lipophilicity, diuretic activity, and carbonic inhibition activity of benzene sulfonamides: a molecular connectivity approach.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 5661-5666, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  P. E. Morgan;C. T. Supuran;J. R. Casey (2004). Carbonic anhydrase inhibitors that directly inhibit anion transport by the human Cl-/HCO3- exchanger, AE1.. MOLECULAR MEMBRANE BIOLOGY, vol. 21, pp. 423-433, ISSN:0968-7688 DOI   Accesso ONLINE all'editore

  J. M. Lehtonen;S. Parkkila;D. Vullo;A. Casini;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 3757-3762, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  F. Abbate;J. Winum;B. V. L;A. Casini;J. Montero;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 231-234, ISSN:0960-894X

  L. Bonnac;A. Innocenti;J. Winum;A. Casini;J. Montero;A. Scozzafava;V. Barragan;C. T. Supuran (2004). Carbonic anhydrase inhibitors: aliphatic N-phosphorylated sulfamates--a novel zinc-anchoring group leading to nanomolar inhibitors.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 19, pp. 275-278, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  A. Cecchi;J. Winum;A. Innocenti;D. Vullo;J. Montero;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 5775-5780, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  C. T. Supuran;B. W. Clare (2004). Quantum theoretic QSAR of benzene derivatives: some enzyme inhibitors.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 19, pp. 237-248, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  A. Weber;A. Casini;A. Heine;D. Kuhn;C. T. Supuran;A. Scozzafava;G. Klebe (2004). Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 47, pp. 550-557, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  M. Jaiswal;P. V. Khadikar;C. T. Supuran (2004). QSAR study on CA inhibitory activity of disulfonamides: effect of halogen substitution.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 12, pp. 2477-2482, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  F. Abbate;A. Coetzee;A. Casini;S. Ciattini;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 337-341, ISSN:0960-894X

  A. Innocenti;J. Antel;M. Wurl;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors: inhibition of human cytosolic isozyme II and mitochondrial isozyme V with a series of benzene sulfonamide derivatives.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 5703-5707, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  D. VULLO; M. FRANCHI; E. GALLORI; J. ANTEL; A. SCOZZAFAVA; C. SUPURAN (2004). Carbonic anhydrase inhibitors. Inhibition of mitochondrial isozyme V with aromatic and heterocyclis sulfonamides.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 47, pp. 1272-1279, ISSN:0022-2623

  Z. H. Chohan;C. T. Supuran;A. Scozzafava (2004). Metalloantibiotics: synthesis and antibacterial activity of cobalt(II), copper(II), nickel(II) and zinc(II) complexes of kefzol.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 19, pp. 79-84, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  C. T. Supuran;D. Vullo;G. Manole;A. Casini;A. Scozzafava (2004). Designing of novel carbonic anhydrase inhibitors and activators.. CURRENT MEDICINAL CHEMISTRY. CARDIOVASCULAR & HEMATOLOGICAL AGENTS, vol. 2, pp. 49-68, ISSN:1568-0169

  J. Winum;A. Casini;F. Mincione;M. Starnotti;J. Montero;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors: N-(p-sulfamoylphenyl)-alpha-D-glycopyranosylamines as topically acting antiglaucoma agents in hypertensive rabbits.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 225-229, ISSN:0960-894X

  S. Zimmerman;A. Innocenti;A. Casini;J. G. Ferry;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 6001-6006, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. T. Balaban;S. C. Basak;A. Beteringhe;D. Mills;C. T. Supuran (2004). QSAR study using topological indices for inhibition of carbonic anhydrase II by sulfanilamides and Schiff bases.. MOLECULAR DIVERSITY, vol. 8, pp. 401-412, ISSN:1381-1991

  S. Pastorekova;A. Casini;A. Scozzafava;D. Vullo;J. Pastorek;C. T. Supuran (2004). Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 869-873, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  F. Abbate;A. Casini;T. Owa;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 217-223, ISSN:0960-894X

  S. Pastorekova;S. Parkkila;J. Pastorek;C. T. Supuran (2004). Carbonic anhydrases: current state of the art, therapeutic applications and future prospects.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 19, pp. 199-229, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  DE LEVAL X; ILIES M; CASINI A; DOGNE JM; SCOZZAFAVA A; E. MASINI; MINCIONE F; STARNOTTI M; SUPURAN CT. (2004). Carbonic anhydrase inhibitors: synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 20, pp. 2796-2804, ISSN:0022-2623, American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671:

  C. Chazalette;B. Masereel;S. Rolin;A. Thiry;A. Scozzafava;A. Innocenti;C. T. Supuran (2004). Carbonic anhydrase inhibitors. Design of anticonvulsant sulfonamides incorporating indane moieties.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 5781-5786, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  S. Rusconi;A. Innocenti;D. Vullo;A. Mastrolorenzo;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 5763-5767, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Z. H. Chohan;H. Pervez;K. M. Khan;A. Rauf;C. T. Supuran (2004). Binding of transition metal ions [cobalt, copper, nickel and zinc] with furanyl-, thiophenyl-, pyrrolyl-, salicylyl- and pyridyl-derived cephalexins as potent antibacterial agents.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 19, pp. 51-56, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  D. Vullo;A. Scozzafava;S. Pastorekova;J. Pastorek;C. T. Supuran (2004). Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 2351-2356, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Innocenti;S. Zimmerman;J. G. Ferry;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors. Inhibition of the zinc and cobalt gamma-class enzyme from the archaeon Methanosarcina thermophila with anions.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 3327-3331, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  S. Rusconi;A. Scozzafava;A. Mastrolorenzo;C. T. Supuran (2004). New advances in HIV entry inhibitors development.. CURRENT DRUG TARGETS. INFECTIOUS DISORDERS, vol. 4, pp. 339-355, ISSN:1568-0053

  M. Ul-Hassan;Z. H. Chohan;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors: Schiff's bases of aromatic and heterocyclic sulfonamides and their metal complexes.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 19, pp. 263-267, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  J. Lehtonen;B. Shen;M. Vihinen;A. Casini;A. Scozzafava;C. T. Supuran;A. Parkkila;J. Saarnio;A. J. Kivelä;A. Waheed;W. S. Sly;S. Parkkila (2004). Characterization of CA XIII, a novel member of the carbonic anhydrase isozyme family.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 279, pp. 2719-2727, ISSN:0021-9258 DOI   Accesso ONLINE all'editore

  A. Thakur;M. Thakur;P. V. Khadikar;C. T. Supuran;P. Sudele (2004). QSAR study on benzenesulphonamide carbonic anhydrase inhibitors: topological approach using Balaban index.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 12, pp. 789-793, ISSN:0968-0896 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;H. Pervez;A. Rauf;K. M. Khan;C. T. Supuran (2004). Isatin-derived antibacterial and antifungal compounds and their transition metal complexes.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 19, pp. 417-423, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  A. Innocenti;M. A. Firnges;J. Antel;M. Wurl;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 5769-5773, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  V. Garaj;L. Puccetti;G. Fasolis;J. Winum;J. Montero;A. Scozzafava;D. Vullo;A. Innocenti;C. T. Supuran (2004). Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 5427-5433, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  A. Mastrolorenzo; G. Zuccati; A. Scozzafava; C.T. Supuran (2004). Carbonic anhydrase inhibitors in dermatology. In: C.T. Supuran, A. Scozzafava, J. Conway. Carbonic anhydrase, its inhibitors and activators, pp. 303-315, Boca Raton: CRC Press.

  Z. H. Chohan;H. Pervez;A. Rauf;K. M. Khan;G. M. Maharvi;C. T. Supuran (2004). Antibacterial and antifugal mono- and di-substituted symmetrical and unsymmetrical triazine-derived Schiff-bases and their transition metal complexes.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 19, pp. 161-168, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  C. T. Supuran;A. Casini;A. Mastrolorenzo;A. Scozzafava (2004). COX-2 selective inhibitors, carbonic anhydrase inhibition and anticancer properties of sulfonamides belonging to this class of pharmacological agents.. MINI-REVIEWS IN MEDICINAL CHEMISTRY, vol. 4, pp. 625-632, ISSN:1389-5575

  V. K. Agrawal;S. Bano;C. T. Supuran;P. V. Khadikar (2004). QSAR study on carbonic anhydrase inhibitors: aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl moieties, with topical activity as antiglaucoma agents.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 39, pp. 593-600, ISSN:0223-5234 DOI   Accesso ONLINE all'editore

  C. T. Supuran;A. Innocenti;A. Mastrolorenzo;A. Scozzafava (2004). Antiviral sulfonamide derivatives.. MINI-REVIEWS IN MEDICINAL CHEMISTRY, vol. 4, pp. 189-200, ISSN:1389-5575

  C. T. Supuran;A. Scozzafava (2004). Benzolamide is not a membrane-impermeant carbonic anhydrase inhibitor.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 19, pp. 269-273, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  J. R. Casey;P. E. Morgan;D. Vullo;A. Scozzafava;A. Mastrolorenzo;C. T. Supuran (2004). Carbonic anhydrase inhibitors. Design of selective, membrane-impermeant inhibitors targeting the human tumor-associated isozyme IX.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 47, pp. 2337-2347, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  E. Svastová;A. Hulíková;M. Rafajová;M. Zat'ovicová;A. Gibadulinová;A. Casini;A. Cecchi;A. Scozzafava;C. T. Supuran;J. Pastorek;S. Pastoreková (2004). Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH.. FEBS LETTERS, vol. 577, pp. 439-445, ISSN:0014-5793 DOI   Accesso ONLINE all'editore

  K. M. Khan;S. Iqbal;M. A. Lodhi;G. M. Maharvi;S. Perveen;M. I. Choudhary;A. Ur-Rahman;Z. H. Chohan;C. T. Supuran (2004). Synthesis and urease enzyme inhibitory effects of some dicoumarols.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 19, pp. 367-371, ISSN:1475-6366

  M. Jaiswal;P. V. Khadikar;A. Scozzafava;C. T. Supuran (2004). Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, pp. 3283-3290, ISSN:0960-894X DOI   Accesso ONLINE all'editore

  Supuran, C. T.; Scozzafava, A.; Pastorekova, S.; Pastorek, J. (2004). CA IX-specific inhibitors. WO 2004/048544.. Numero: PCT/US2003/037783 C.T. Supuran, A. Scozzafava, S. Pastorekova, J. Pastorek

  A. Casini;S. Caccia;A. Scozzafava;C. T. Supuran (2003). Carbonic anhydrase activators. The selective serotonin reuptake inhibitors fluoxetine, sertraline and citalopram are strong activators of isozymes I and II.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 13, pp. 2765-2768, ISSN:0960-894X

  D. Vullo;M. Franchi;E. Gallori;J. Pastorek;A. Scozzafava;S. Pastorekova;C. T. Supuran (2003). Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 13, pp. 1005-1009, ISSN:0960-894X DOI  

  A. Scozzafava;T. Owa;A. Mastrolorenzo;C. T. Supuran (2003). Anticancer and antiviral sulfonamides.. CURRENT MEDICINAL CHEMISTRY, vol. 10, pp. 925-953, ISSN:0929-8673

  C. T. Supuran (2003). Indisulam: an anticancer sulfonamide in clinical development.. EXPERT OPINION ON INVESTIGATIONAL DRUGS, vol. 12, pp. 283-287, ISSN:1354-3784 DOI   Accesso ONLINE all'editore

  C. T. Supuran;A. Casini;A. Scozzafava (2003). Protease inhibitors of the sulfonamide type: anticancer, antiinflammatory, and antiviral agents.. MEDICINAL RESEARCH REVIEWS, vol. 23, pp. 535-558, ISSN:0198-6325 DOI   Accesso ONLINE all'editore

  M. Ilies;M. D. Banciu;A. Scozzafava;M. A. Ilies;M. T. Caproiu;C. T. Supuran (2003). Protease inhibitors: synthesis of bacterial collagenase and matrix metalloproteinase inhibitors incorporating arylsulfonylureido and 5-dibenzo-suberenyl/suberyl moieties.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, pp. 2227-2239, ISSN:0968-0896

  J. Winum;D. Vullo;A. Casini;J. Montero;A. Scozzafava;C. T. Supuran (2003). Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, tumor-associated isozyme IX with sulfamates including EMATE also acting as steroid sulfatase inhibitors.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 46, pp. 2197-2204, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  D. Vullo;M. Franchi;E. Gallori;J. Pastorek;A. Scozzafava;S. Pastorekova;C. T. Supuran (2003). Carbonic anhydrase inhibitors. inhibition of cytosolic isozymes I and II and transmembrane, cancer-associated isozyme IX with anions.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 18, pp. 403-406, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  F. Abbate;A. Casini;A. Scozzafava;C. T. Supuran (2003). Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the perfluorobenzoyl analogue of methazolamide. Implications for the drug design of fluorinated inhibitors.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 18, pp. 303-308, ISSN:1475-6366

  M. A. Santos;S. Marques;M. Gil;M. Tegoni;A. Scozzafava;C. T. Supuran (2003). Protease inhibitors: synthesis of bacterial collagenase and matrix metalloproteinase inhibitors incorporating succinyl hydroxamate and iminodiacetic acid hydroxamate moieties.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 18, pp. 233-242, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  A. Casini;J. Winum;J. Montero;A. Scozzafava;C. T. Supuran (2003). Carbonic anhydrase inhibitors: inhibition of cytosolic isozymes I and II with sulfamide derivatives.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 13, pp. 837-840, ISSN:0960-894X

  V. K. Agrawal;S. Srivastava;P. V. Khadikar;C. T. Supuran (2003). Quantitative structure-activity relationship study on sulfanilamide schiff's bases: carbonic anhydrase (CA) inhibitors.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, pp. 5353-5362, ISSN:0968-0896

  A. Casini;J. Antel;F. Abbate;A. Scozzafava;S. David;H. Waldeck;S. Schäfer;C. T. Supuran (2003). Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 13, pp. 841-845, ISSN:0960-894X

  Alvarez BV; Loiselle FB; Supuran CT; Schwartz GJ; Casey JR. (2003). Direct extracellular interaction between carbonic anhydrase IV and the human NBC1 sodium/bicarbonate co-transporter.. BIOCHEMISTRY, pp. 12321-12329, ISSN:0006-2960

  A. W. Cuthbert;C. T. Supuran;L. J. MacVinish (2003). Bicarbonate-dependent chloride secretion in Calu-3 epithelia in response to 7,8-benzoquinoline.. THE JOURNAL OF PHYSIOLOGY, vol. 551, pp. 79-92, ISSN:0022-3751 DOI   Accesso ONLINE all'editore

  M. A. Ilies;D. Vullo;J. Pastorek;A. Scozzafava;M. Ilies;M. T. Caproiu;S. Pastorekova;C. T. Supuran (2003). Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 46, pp. 2187-2196, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  A. Casini;A. Scozzafava;F. Mincione;L. Menabuoni;M. Starnotti;C. T. Supuran (2003). Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating esters and amides of 3- and 4-carboxybenzolamide.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 13, pp. 2867-2873, ISSN:0960-894X

  A. MASTROLORENZO; G. ZUCCATI; D. MASSI; M.G. GABRIELLI; A. CASINI; A. SCOZZAFAVA; C.T. SUPURAN. (2003). iMMUNOHISTOCHEMICAL EXPRESSION OF CARBONIC ANHYDRASE ISOENZYMES IN HUMAN SKIN. EUROPEAN JOURNAL OF DERMATOLOGY, vol. 13, pp. 440-444, ISSN:1167-1122, John Libby Eurotext Ltd:127 avenue de la Republique, F 92120 Montrouge France:011 33 1 46730660, EMAIL: marketing@jle.com, INTERNET: http://www.john-libbey-eurotext.fr, Fax: 011 33 1 40840999:

  A. Mastrolorenzo;G. Zuccati;D. Massi;M. G. Gabrielli;A. Casini;A. Scozzafava;C. T. Supuran (2003). Immunohistochemical study of carbonic anhydrase isozymes in human skin.. EUROPEAN JOURNAL OF DERMATOLOGY, vol. 13, pp. 440-444, ISSN:1167-1122

  A. SCOZZAFAVA; C. SUPURAN; A. CASINI (2003). CARBONIC ANHYDRASE INHIBITORS. MEDICINAL RESEARCH REVIEWS, vol. 2, pp. 146-189, ISSN:0198-6325

  M. FRANCHI; D. VULLO; E. GALLORI; J. ANTEL; M. WURL; A. SCOZZAFAVA; C. SUPURAN (2003). Carbonic anhydrase inhibitors: inhibition of human and murine mitochondrial isozymes V with anions.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 13, pp. 2857-2861, ISSN:0960-894X, Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010:

  A. Scozzafava;C. T. Supuran (2003). Hydroxyurea is a carbonic anhydrase inhibitor.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, pp. 2241-2246, ISSN:0968-0896

  De Simone G; Menchise V; Omaggio S; Pedone C; Scozzafava A; Supuran CT. (2003). Design of weakly basic thrombin inhibitors incorporating novel P1 binding functions: molecular and X-ray crystallographic studies.. BIOCHEMISTRY, pp. 9013-9021, ISSN:0006-2960

  M. Franchi;D. Vullo;E. Gallori;J. Pastorek;A. Russo;A. Scozzafava;S. Pastorekova;C. T. Supuran (2003). Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, cancer-associated isozyme IX with lipophilic sulfonamides.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 18, pp. 333-338, ISSN:1475-6366

  Z. H. Chohan;A. Scozzafava;C. T. Supuran (2003). Zinc complexes of benzothiazole-derived Schiff bases with antibacterial activity.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 18, pp. 259-263, ISSN:1475-6366

  A. Casini;F. Abbate;A. Scozzafava;C. T. Supuran (2003). Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a bis-sulfonamide-two heads are better than one?. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 13, pp. 2759-2763, ISSN:0960-894X

  J. Winum;D. Vullo;A. Casini;J. Montero;A. Scozzafava;C. T. Supuran (2003). Carbonic anhydrase inhibitors: inhibition of transmembrane, tumor-associated isozyme IX, and cytosolic isozymes I and II with aliphatic sulfamates.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 46, pp. 5471-5477, ISSN:0022-2623 DOI   Accesso ONLINE all'editore

  M.FERRARONI; F.BRIGANTI; W.R.CHEGWIDDEN; C.T.SUPURAN; A.SCOZZAFAVA (2002). Crystal analysis of Aromatic sulfonamide binding to native and (Zn)2adduct to Human Carbonic Anhydrase I Michigan 1. INORGANICA CHIMICA ACTA, vol. 339, pp. 135-144, ISSN:0020-1693

  A. Casini;F. Mincione;D. Vullo;L. Menabuoni;A. Scozzafava;C. T. Supuran (2002). Carbonic anhydrase inhibitors with strong topical antiglaucoma properties incorporating a 4-(2-aminopyrimidin-4-yl-amino)-benzenesulfonamide scaffold.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 17, pp. 9-18, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  A. Scozzafava;C. T. Supuran (2002). Carbonic anhydrase activators: high affinity isozymes I, II, and IV activators, incorporating a beta-alanyl-histidine scaffold.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 45, pp. 284-291, ISSN:0022-2623

  A. Casini;A. Scozzafava;F. Mincione;L. Menabuoni;C. T. Supuran (2002). Carbonic anhydrase inhibitors: synthesis of water soluble sulfonamides incorporating a 4-sulfamoylphenylmethylthiourea scaffold, with potent intraocular pressure lowering properties.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 17, pp. 333-343, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;A. Scozzafava;C. T. Supuran (2002). Unsymmetrical 1,1'-disubstituted ferrocenes: synthesis of Co(ii), Cu(ii), Ni(ii) and Zn(ii) chelates of ferrocenyl -1-thiadiazolo-1'-tetrazole, -1-thiadiazolo-1'-triazole and -1-tetrazolo-1'-triazole with antimicrobial properties.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 17, pp. 261-266, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;M. S. Iqbal;H. S. Iqbal;A. Scozzafava;C. T. Supuran (2002). Transition metal acetylsalicylates and their anti-inflammatory activity.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 17, pp. 87-91, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  B. Masereel;S. Rolin;F. Abbate;A. Scozzafava;C. T. Supuran (2002). Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 45, pp. 312-320, ISSN:0022-2623

  C. T. Supuran (2002). Indisulam. Eisai.. IDRUGS, vol. 5, pp. 1075-1079, ISSN:1369-7056

  D. Sterling;N. J. D;C. T. Supuran;J. R. Casey (2002). The functional and physical relationship between the DRA bicarbonate transporter and carbonic anhydrase II.. AMERICAN JOURNAL OF PHYSIOLOGY. CELL PHYSIOLOGY, vol. 283, pp. C1522-C1529, ISSN:0363-6143 DOI   Accesso ONLINE all'editore

  A. Scozzafava;C. T. Supuran (2002). Protease inhibitors: synthesis of matrix metalloproteinase and bacterial collagenase inhibitors incorporating 5-amino-2-mercapto-1,3,4-thiadiazole zinc binding functions.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 12, pp. 2667-2672, ISSN:0960-894X

  C. T. Supuran;A. Scozzafava;B. W. Clare (2002). Bacterial protease inhibitors.. MEDICINAL RESEARCH REVIEWS, vol. 22, pp. 329-372, ISSN:0198-6325 DOI   Accesso ONLINE all'editore

  F. Abbate;C. T. Supuran;A. Scozzafava;P. Orioli;M. T. Stubbs;G. Klebe (2002). Nonaromatic sulfonamide group as an ideal anchor for potent human carbonic anhydrase inhibitors: role of hydrogen-bonding networks in ligand binding and drug design.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 45, pp. 3583-3587, ISSN:0022-2623

  A. Casini;A. Scozzafava;C. T. Supuran (2002). Cysteine-modifying agents: a possible approach for effective anticancer and antiviral drugs.. ENVIRONMENTAL HEALTH PERSPECTIVES, vol. 110 Suppl 5, pp. 801-806, ISSN:0091-6765

  Z. H. Chohan;H. Pervez;A. Rauf;A. Scozzafava;C. T. Supuran (2002). Antibacterial Co(II), Cu(II), Ni(II) and Zn(II) complexes of thiadiazole derived furanyl, thiophenyl and pyrrolyl Schiff bases.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 17, pp. 117-122, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;H. Pervez;A. Rauf;C. T. Supuran (2002). Antibacterial Role of SO(4), NO(3), C(2)O(4) and CH(3)CO(2) Anions on Cu(II) and Zn(II) Complexes of a Thiadiazole-derived Pyrrolyl Schiff Base.. METAL-BASED DRUGS, vol. 8, pp. 263-267, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  A. Scozzafava;A. Casini;C. T. Supuran (2002). Targeting cysteine residues of biomolecules: new approaches for the design of antiviral and anticancer drugs.. CURRENT MEDICINAL CHEMISTRY, vol. 9, pp. 1167-1185, ISSN:0929-8673

  FERRARONI M.; BRIGANTI F.; CHEGWIDDEN W.R.; SUPURAN C.T.; A. SCOZZAFAVA (2002). Crystal analysis of aromatic sulfonamide binding to native and (Zn)2 adduct of human carbonic anhydrase I Michigan 1.. INORGANICA CHIMICA ACTA, vol. 339, pp. 135-144, ISSN:0020-1693, Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598 Editore precedente:Prof Ugo Croatto Luogo pubbl. Padova Ultimo luogo pubblicazione: Lausanne.:

  A. SCOZZAFAVA; C. SUPURAN (2002). CARBONIC ANHYDRASE ACTIVATORS: HIGH AFFINITY ISOZYMES I, II AND IV ACTIVATORS INCORPORATING A ALANYL-HISTIDINE SCAFFOLS. JOURNAL OF MEDICINAL CHEMISTRY, vol. 45, pp. 284-291, ISSN:0022-2623

  Z. H. Chohan;A. Rauf;C. T. Supuran (2002). Antibacterial Co(II) and Ni(II) Complexes of N-(2-Furanylmethylene)-2-Aminothiadiazole and Role of SO(4), NO(3), C(2)O(4) and CH(3)CO(2) anions on Biological Properties.. METAL-BASED DRUGS, vol. 8, pp. 287-291, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;M. A. Farooq;A. Scozzafava;C. T. Supuran (2002). Antibacterial Schiff bases of oxalyl-hydrazine/diamide incorporating pyrrolyl and salicylyl moieties and of their zinc(II) complexes.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 17, pp. 1-7, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  A. Scozzafava;C. T. Supuran (2002). Carbonic anhydrase activators: human isozyme II is strongly activated by oligopeptides incorporating the carboxyterminal sequence of the bicarbonate anion exchanger AE1.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 12, pp. 1177-1180, ISSN:0960-894X

  C. U. Nielsen;C. T. Supuran;A. Scozzafava;S. Frokjaer;B. Steffansen;B. Brodin (2002). Transport characteristics of L-carnosine and the anticancer derivative 4-toluenesulfonylureido-carnosine in a human epithelial cell line.. PHARMACEUTICAL RESEARCH, vol. 19, pp. 1337-1344, ISSN:0724-8741

  Z. H. Chohan;A. Rau;S. Noreen;A. Scozzafava;C. T. Supuran (2002). Antibacterial cobalt(II), nickel(II) and zinc(II) complexes of nicotinic acid-derived Schiff-bases.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 17, pp. 101-106, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  A. Scozzafava;C. T. Supuran (2002). Carbonic anhydrase inhibitors. Preparation of potent sulfonamides inhibitors incorporating bile acid tails.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 12, pp. 1551-1557, ISSN:0960-894X

  A. Scozzafava;L. Menabuoni;F. Mincione;C. T. Supuran (2002). Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 45, pp. 1466-1476, ISSN:0022-2623

  F. Maestrelli; P. Mura; A. Casini; F. Mincione; A. Scozzafava; C.T. Supuran (2002). Cyclodextrin complexes of sulfonamide carbonic anhydrase inhibitors as long-lasting topically acting antiglaucoma agents. JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 91, pp. 2211-2219, ISSN:0022-3549

  M. FERRARONI; S. TILLI; F. BRIGANTI; W. CHEGWIDDEN; C. SUPURAN; K. WIEBAUER; R. TASHIAN; A. SCOZZAFAVA (2002). Crystal structure of a zinc-activated variant of Human Carbonic Anhydrase I, CA I Michigan 1: evidence for a second zinc binding site involving arginine coordination. BIOCHEMISTRY, vol. 41, pp. 6237-6244, ISSN:0006-2960 DOI  

  A. Scozzafava;A. Mastrolorenzo;C. T. Supuran (2002). Non-peptidic chemokine receptors antagonists as emerging anti-HIV agents.. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 17, pp. 69-76, ISSN:1475-6366 DOI   Accesso ONLINE all'editore

  C. Chazalette;M. Riviere-Baudet;A. Scozzafava;F. Abbate;Z. B. Maarouf;C. T. Supuran (2001). Carbonic anhydrase inhibitors, interaction of boron derivatives with isozymes I and II: a new binding site for hydrophobic inhibitors at the entrance of the active site as shown by docking studies.. JOURNAL OF ENZYME INHIBITION, vol. 16, pp. 125-133, ISSN:8755-5093

  C. T. Supuran; F. Briganti; S. Tilli; W. R. Chegwidden; A. Scozzafava (2001). Carbonic anhydrase inhibitors: sulfonamides as antitumor agents?. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 9, pp. 703-714, ISSN:0968-0896

  A. Scozzafava;I. Saramet;M. D. Banciu;C. T. Supuran (2001). Carbonic anhydrase activity modulators: synthesis of inhibitors and activators incorporating 2-substituted-thiazol-4-yl-methyl scaffolds.. JOURNAL OF ENZYME INHIBITION, vol. 16, pp. 351-358, ISSN:8755-5093

  A. Scozzafava;F. Mincione;L. Menabuoni;C. T. Supuran (2001). Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating phthaloyl and phthalimido moieties.. DRUG DESIGN AND DISCOVERY, vol. 17, pp. 337-348, ISSN:1055-9612

  I. Fenesan;R. Popescu;C. T. Supuran;S. Nicoara;M. Culea;N. Palibroda;Z. Moldovan;O. Cozar (2001). Electron impact mass spectral interpretation for some thiophosphoryl-p-acetylaminobenzenesulfonamides.. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, vol. 15, pp. 721-729, ISSN:0951-4198 DOI   Accesso ONLINE all'editore

  C. Chazalette;M. Rivière-Baudet;C. T. Supuran;A. Scozzafava (2001). Carbonic anhydrase inhibitors: allylsulfonamide, styrene sulfonamide, N-allyl sulfonamides and some of their Si, Ge, and B derivatives.. JOURNAL OF ENZYME INHIBITION, vol. 16, pp. 475-489, ISSN:8755-5093

  A. Casini;F. Mincione;M. A. Ilies;L. Menabuoni;A. Scozzafava;C. T. Supuran (2001). Carbonic anhydrase inhibitors: synthesis and inhibition against isozymes I, II and IV of topically acting antiglaucoma sulfonamides incorporating cis-5-norbornene-endo-3-carboxy-2-carboxamido moieties.. JOURNAL OF ENZYME INHIBITION, vol. 16, pp. 113-123, ISSN:8755-5093

  B. W. Clare;A. Scozzafava;C. T. Supuran (2001). Protease inhibitors: synthesis of a series of bacterial collagenase inhibitors of the sulfonyl amino acyl hydroxamate type.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 44, pp. 2253-2258, ISSN:0022-2623

  Z. H. Chohan;A. Munawar;C. T. Supuran (2001). Transition Metal Ion Complexes of Schiff-bases. Synthesis, Characterization and Antibacterial Properties.. METAL-BASED DRUGS, vol. 8, pp. 137-143, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;M. A. Farooq;C. T. Supuran (2001). Copper (II) Acylhydrazinates. Their Synthesis and Characterization.. METAL-BASED DRUGS, vol. 8, pp. 171-177, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  Z. H. Chohan;M. F. Jaffery;C. T. Supuran (2001). Antibacterial Co(II), Cu(II), Ni(II) and Zn(II) Complexes of Thiadiazoles Schiff Bases.. METAL-BASED DRUGS, vol. 8, pp. 95-101, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  B. W. Clare;A. Scozzafava;C. T. Supuran (2001). Protease inhibitors, part 13: Specific, weakly basic thrombin inhibitors incorporating sulfonyl dicyandiamide moieties in their structure.. JOURNAL OF ENZYME INHIBITION, vol. 16, pp. 1-13, ISSN:8755-5093

  F. Mincione;M. Starnotti;L. Menabuoni;A. Scozzafava;A. Casini;C. T. Supuran (2001). Carbonic anhydrase inhibitors: 4-sulfamoyl-benzenecarboxamides and 4-chloro-3-sulfamoyl-benzenecarboxamides with strong topical antiglaucoma properties.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 11, pp. 1787-1791, ISSN:0960-894X

  A. Scozzafava;A. Mastrolorenzo;C. T. Supuran (2001). Antimycobacterial activity of 3,4-dichlorophenyl-ureas, N,N-diphenyl-ureas and related derivatives.. JOURNAL OF ENZYME INHIBITION, vol. 16, pp. 425-432, ISSN:8755-5093

  A. Scozzafava;A. Mastrolorenzo;C. T. Supuran (2001). Antimycobacterial activity of 9-sulfonylated/sulfenylated-6-mercaptopurine derivatives.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 11, pp. 1675-1678, ISSN:0960-894X

  A. Scozzafava;L. Menabuoni;F. Mincione;G. Mincione;C. T. Supuran (2001). Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 11, pp. 575-582, ISSN:0960-894X

  A. Scozzafava;A. Mastrolorenzo;C. T. Supuran (2001). Arylsulfonyl-N,N-dialkyl-dithiocarbamates as tumor cell growth inhibitors: novel agents targeting beta-tubulin?. JOURNAL OF ENZYME INHIBITION, vol. 16, pp. 55-63, ISSN:8755-5093

  C. T. Supuran;B. W. Clare (2001). Orbital symmetry in QSAR: some Schiff's base inhibitors of carbonic anhydrase.. SAR AND QSAR IN ENVIRONMENTAL RESEARCH, vol. 12, pp. 17-29, ISSN:1062-936X DOI   Accesso ONLINE all'editore

  M. Ul-Hassan;A. Scozzafava;Z. H. Chohan;C. T. Supuran (2001). Carbonic anhydrase inhibitors: metal complexes of a sulfanilamide derived Schiff base and their interaction with isozymes I, II and IV.. JOURNAL OF ENZYME INHIBITION, vol. 16, pp. 499-505, ISSN:8755-5093

  C. T. Supuran;A. Scozzafava (2000). Activation of carbonic anhydrase isozymes.. EXS, pp. 197-219, ISSN:1023-294X

  A. Scozzafava;C. T. Supuran (2000). Carbonic anhydrase and matrix metalloproteinase inhibitors: sulfonylated amino acid hydroxamates with MMP inhibitory properties act as efficient inhibitors of CA isozymes I, II, and IV, and N-hydroxysulfonamides inhibit both these zinc enzymes.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 43, pp. 3677-3687, ISSN:0022-2623

  A. Mastrolorenzo;A. Scozzafava;C. T. Supuran (2000). Antifungal activity of Ag(I) and Zn(II) complexes of aminobenzolamide (5-sulfanilylamido-1,3,4-thiadiazole-2-sulfonamide) derivatives.. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 517-531, ISSN:8755-5093

  C. T. Supuran;A. Scozzafava (2000). Carbonic anhydrase inhibitors--Part 94. 1,3,4-thiadiazole-2-sulfonamidederivatives as antitumor agents?. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 35, pp. 867-874, ISSN:0223-5234

  A. Scozzafava;C. T. Supuran (2000). Carbonic anhydrase inhibitors: synthesis of N-morpholylthiocarbonylsulfenylamino aromatic/heterocyclic sulfonamides and their interaction with isozymes I, II and IV.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 10, pp. 1117-1120, ISSN:0960-894X

  F. Briganti; S. Tilli; G. Mincione; F. Mincione; L. Menabuoni; C. T. Supuran (2000). Carbonic anhydrase inhibitors. metal complexes of 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide with topical intraocular pressure lowering properties: the influence of metal ions upon the pharmacological activity.. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 185-200, ISSN:8755-5093

  C. T. Supuran; F. Briganti; L. Menabuoni; G. Mincione; F. Mincione; A. Scozzafava (2000). Carbonic anhydrase inhibitors - part 78(#). Synthesis of water-soluble sulfonamides incorporating beta-alanyl moieties, possessing long lasting-intraocular pressure lowering properties via the topical route.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 35, pp. 309-321, ISSN:0223-5234

  M. Barboiu; C. T. Supuran; L. Menabuoni; A. Scozzafava; F. Mincione; F. Briganti; G. Mincione (2000). Carbonic anhydrase inhibitors. Synthesis of topically effective intraocular pressure lowering agents derived from 5-(omega-aminoalkylcarboxamido)-1,3,4-thiadiazole-2-sulfonamide.. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 23-46, ISSN:8755-5093

  A. Scozzafava;C. T. Supuran (2000). Protease inhibitors - part 5. Alkyl/arylsulfonyl- and arylsulfonylureido-/arylureido- glycine hydroxamate inhibitors of Clostridium histolyticum collagenase.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 35, pp. 299-307, ISSN:0223-5234

  A. Mastrolorenzo;A. Scozzafava;C. T. Supuran (2000). The antifungal activity of sulfonylated/carboxylated derivatives of dibenzo-1,4-dioxine-2-acetyloxime may be due to inhibition of lanosterol-14alpha-demethylase.. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 557-569, ISSN:8755-5093

  A. Scozzafava;C. T. Supuran (2000). Protease inhibitors: synthesis of clostridium histolyticum collagenase inhibitors incorporating sulfonyl-L-alanine hydroxamate moieties.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 10, pp. 499-502, ISSN:0960-894X

  A. Scozzafava;B. Iorga;C. T. Supuran (2000). Carbonic anhydrase activators: synthesis of high affinity isozymes I, II and IV activators, derivatives of 4-(4-tosylureido-amino acyl)ethyl-1H-imidazole (histamine derivatives).. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 139-161, ISSN:8755-5093

  A. Mastrolorenzo;C. T. Supuran (2000). Antifungal Activity of Ag(I) and Zn(II) Complexes of Sulfacetamide Derivatives.. METAL-BASED DRUGS, vol. 7, pp. 49-54, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  M. A. Ilies;C. T. Supuran;A. Scozzafava (2000). Carbonic anhydrase inhibitors. Part 91. Metal complexes of heterocyclic sulfonamides as potential pharmacological agents in the treatment of gastric Acid secretion imbalances.. METAL-BASED DRUGS, vol. 7, pp. 57-62, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  A. Scozzafava;M. D. Banciu;A. Popescu;C. T. Supuran (2000). Carbonic anhydrase inhibitors: inhibition of isozymes I, II and IV by sulfamide and sulfamic acid derivatives.. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 443-453, ISSN:8755-5093

  A. Casini;A. Scozzafava;F. Mincione;L. Menabuoni;M. A. Ilies;C. T. Supuran (2000). Carbonic anhydrase inhibitors: water-soluble 4-sulfamoylphenylthioureas as topical intraocular pressure-lowering agents with long-lasting effects.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 43, pp. 4884-4892, ISSN:0022-2623

  C. T. Supuran;A. Scozzafava (2000). Carbonic anhydrase activators: synthesis of high affinity isozymes I, II and IV activators, derivatives of 4-(arylsulfonylureido-amino acyl)ethyl-1H-imidazole.. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 471-486, ISSN:8755-5093

  A. Scozzafava;M. D. Banciu;A. Popescu;C. T. Supuran (2000). Carbonic anhydrase inhibitors: synthesis of Schiff bases of hydroxybenzaldehydes with aromatic sulfonamides and their reactions with arylsulfonyl isocyanates.. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 533-546, ISSN:8755-5093

  C. T. Supuran;A. Scozzafava (2000). Carbonic anhydrase inhibitors: aromatic sulfonamides and disulfonamides act as efficient tumor growth inhibitors.. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 597-610, ISSN:8755-5093

  B. W. Clare;C. T. Supuran (2000). Carbonic anhydrase inhibitors. Part 86. A QSAR study on some sulfonamide drugs which lower intra-ocular pressure, using the ACE non-linear statistical method.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 35, pp. 859-865, ISSN:0223-5234

  A. Scozzafava;A. Mastrolorenzo;C. T. Supuran (2000). Arylsulfonyl-N,N-diethyl-dithiocarbamates: a novel class of antitumor agents.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 10, pp. 1887-1891, ISSN:0960-894X

  I. Fenesan;R. Popescu;A. Scozzafava;V. Crucin;E. Mateiciuc;R. Bauer;M. A. Ilies;C. T. Supuran (2000). Carbonic anhydrase inhibitors; phosphoryl-sulfonamides--a new class of high affinity inhibitors of isozymes I and II.. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 297-310, ISSN:8755-5093

  A. Scozzafava;M. A. Ilies;G. Manole;C. T. Supuran (2000). Protease inhibitors. Part 12. Synthesis of potent matrix metalloproteinase and bacterial collagenase inhibitors incorporating sulfonylated N-4-nitrobenzyl-beta-alanine hydroxamate moieties.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 11, pp. 69-79, ISSN:0928-0987

  A. Scozzafava;C. T. Supuran (2000). Protease inhibitors: synthesis of potent bacterial collagenase and matrix metalloproteinase inhibitors incorporating N-4-nitrobenzylsulfonylglycine hydroxamate moieties.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 43, pp. 1858-1865, ISSN:0022-2623

  A. Scozzafava;C. T. Supuran (2000). Carbonic anhydrase activators - part 21. Novel activators of isozymes I, II and IV incorporating carboxamido and ureido histamine moieties.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 35, pp. 31-39, ISSN:0223-5234

  A. Mastrolorenzo;A. Scozzafava;C. T. Supuran (2000). 4-toluenesulfonylureido derivatives of amines, amino acids and dipeptides: a novel class of potential antitumor agents.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 11, pp. 325-332, ISSN:0928-0987

  C. T. Supuran;A. Scozzafava (2000). Protease inhibitors. Part 7. Inhibition of Clostridium histolyticum collagenase with sulfonylated derivatives of L-valine hydroxamate.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 10, pp. 67-76, ISSN:0928-0987

  C. T. Supuran; A. Scozzafava; M. A. Ilies; F. Briganti (2000). Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating 2,4,6-trisubstituted-pyridinium-ethylcarboxamido moieties possessing membrane-impermeability and in vivo selectivity for the membrane-bound (CA IV) versus the cytosolic (CA I and CA II) isozymes.. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 381-401, ISSN:8755-5093

  C. T. Supuran; A. Scozzafava; F. Briganti; B. W. Clare (2000). Protease inhibitors: synthesis and QSAR study of novel classes of nonbasic thrombin inhibitors incorporating sulfonylguanidine and O-methylsulfonylisourea moieties at P1.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 43, pp. 1793-1806, ISSN:0022-2623

  A. Guerri; F. Briganti; A. Scozzafava; C. T. Supuran; S. Mangani (2000). Mechanism of cyanamide hydration catalyzed by carbonic anhydrase II suggested by cryogenic X-ray diffraction.. BIOCHEMISTRY, vol. 39, pp. 12391-12397, ISSN:0006-2960

  C. T. Supuran; F. Briganti; A. Scozzafava; M. A. Ilies (2000). Protease inhibitors: Part 4. Synthesis of weakly basic thrombin inhibitors incorporating pyridinium-sulfanilylaminoguanidine moieties.. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 335-356, ISSN:8755-5093

  B. W. Clare; A. Scozzafava; F. Briganti; B. Iorga; C. T. Supuran (2000). Protease inhibitors. Part 2. Weakly basic thrombin inhibitors incorporating sulfonyl-aminoguanidine moieties as S1 anchoring groups: synthesis and structure-activity correlations.. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 235-264, ISSN:8755-5093

  A. Scozzafava; F. Briganti; M. A. Ilies; C. T. Supuran (2000). Carbonic anhydrase inhibitors: synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 43, pp. 292-300, ISSN:0022-2623

  C. T. Supuran; F. Briganti; G. Mincione; A. Scozzafava (2000). Protease inhibitors: Synthesis of L-alanine hydroxamate sulfonylated derivatives as inhibitors of clostridium histolyticum collagenase.. JOURNAL OF ENZYME INHIBITION, vol. 15, pp. 111-128, ISSN:8755-5093

  G. Renzi;A. Scozzafava;C. T. Supuran (2000). Carbonic anhydrase inhibitors: topical sulfonamide antiglaucoma agents incorporating secondary amine moieties.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 10, pp. 673-676, ISSN:0960-894X

  A. Scozzafava;C. T. Supuran (2000). Carbonic anhydrase activators. Part 24. High affinity isozymes I, II and IV activators, derivatives of 4-(4-chlorophenylsulfonylureido-amino acyl)ethyl-1H-imidazole.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 10, pp. 29-41, ISSN:0928-0987

  M. Ilies;C. T. Supuran;A. Scozzafava;A. Casini;F. Mincione;L. Menabuoni;M. T. Caproiu;M. Maganu;M. D. Banciu (2000). Carbonic anhydrase inhibitors: sulfonamides incorporating furan-, thiophene- and pyrrole-carboxamido groups possess strong topical intraocular pressure lowering properties as aqueous suspensions.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 8, pp. 2145-2155, ISSN:0968-0896

  A. Mastrolorenzo;A. Scozzafava;C. T. Supuran (2000). Antifungal activity of silver and zinc complexes of sulfadrug derivatives incorporating arylsulfonylureido moieties.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 11, pp. 99-107, ISSN:0928-0987

  A. Scozzafava; L. Menabuoni; F. Mincione; F. Briganti; G. Mincione; C. T. Supuran (2000). Carbonic anhydrase inhibitors: perfluoroalkyl/aryl-substituted derivatives of aromatic/heterocyclic sulfonamides as topical intraocular pressure-lowering agents with prolonged duration of action.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 43, pp. 4542-4551, ISSN:0022-2623

  F. Briganti; A. Scozzafava; C. T. Supuran (1999). Novel carbonic anhydrase isozymes I, II and IV activators incorporating sulfonyl-histamino moieties.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 9, pp. 2043-2048, ISSN:0960-894X

  A. Scozzafava; F. Briganti; C.T. Supuran (1999). Protease inhibitors - Part 3. Synthesis of non-basic thrombin inhibitors incorporating pyridinium-sulfanilylguanidine moieties at the P1 site.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 34, pp. 939-952, ISSN:0223-5234

  C. T. Supuran; A. Scozzafava; L. Menabuoni; F. Mincione; F. Briganti; G. Mincione (1999). Carbonic anhydrase inhibitors. Part 71. Synthesis and ocular pharmacology of a new class of water-soluble, topically effective intraocular pressure lowering sulfonamides incorporating picolinoyl moieties.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 8, pp. 317-328, ISSN:0928-0987

  C. T. Supuran; A. Scozzafava; F. Briganti (1999). Carbonic anhydrase inhibitors: N-cyanosulfonamides, a new class of high affinity isozyme II and IV inhibitors.. JOURNAL OF ENZYME INHIBITION, vol. 14, pp. 289-306, ISSN:8755-5093

  A. Scozzafava;C. T. Supuran (1999). Carbonic anhydrase inhibitors. Arylsulfonylureido- and arylureido-substituted aromatic and heterocyclic sulfonamides: towards selective inhibitors of carbonic anhydrase isozyme I.. JOURNAL OF ENZYME INHIBITION, vol. 14, pp. 343-363, ISSN:8755-5093

  C. T. Supuran;A. Scozzafava (1999). Carbonic anhydrase activators: amino acyl/dipeptidyl histamine derivatives bind with high affinity to isozymes I, II and IV and act as efficient activators.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 7, pp. 2915-2923, ISSN:0968-0896

  M. Barboiu;C. T. Supuran;A. Scozzafava;C. Guran;P. Diaconescu;M. Bojin;V. Iluc;L. Cot (1999). Functionalized Derivatives of Benzo-Crown Ethers. Part 4. Antifungal Macrocyclic Supramolecular Complexes of Transition Metal Ions Acting as Lanosterol-14-alpha-Demethylase Ihibitors.. METAL-BASED DRUGS, vol. 6, pp. 101-110, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  J. Borras; A. Scozzafava; L. Menabuoni; F. Mincione; F. Briganti; G. Mincione; C. T. Supuran (1999). Carbonic anhydrase inhibitors: synthesis of water-soluble, topically effective intraocular pressure lowering aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl moieties: is the tail more important than the ring?. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 7, pp. 2397-2406, ISSN:0968-0896

  A. Popescu; A. Simion; A. Scozzafava; F. Briganti; C. T. Supuran (1999). Carbonic anhydrase inhibitors. Schiff bases of some aromatic sulfonamides and their metal complexes: towards more selective inhibitors of carbonic anhydrase isozyme IV.. JOURNAL OF ENZYME INHIBITION, vol. 14, pp. 407-423, ISSN:8755-5093

  A. Scozzafava; F. Briganti; G. Mincione; L. Menabuoni; F. Mincione; C. T. Supuran (1999). Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 42, pp. 3690-3700, ISSN:0022-2623

  C. T. Supuran; A. Scozzafava; F. Mincione; L. Menabuoni; F. Briganti; G. Mincione; M. Jitianu (1999). Carbonic anhydrase inhibitors. Part 60(#). The topical intraocular pressure-lowering properties of metal complexes of a heterocyclic sulfonamide: influence of the metal ion upon biological activity.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 34, pp. 585-595, ISSN:0223-5234

  F. Briganti; S. Mangani; A. Scozzafava; G. Vernaglione; C. T. Supuran (1999). Carbonic anhydrase catalyzes cyanamide hydration to urea: is it mimicking the physiological reaction?. JBIC, vol. 4, pp. 528-536, ISSN:0949-8257

  A. Scozzafava; L. Menabuoni; F. Mincione; F. Briganti; G. Mincione; C. T. Supuran (1999). Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring?. JOURNAL OF MEDICINAL CHEMISTRY, vol. 42, pp. 2641-2650, ISSN:0022-2623

  L. Menabuoni; A. Scozzafava; F. Mincione; F. Briganti; G. Mincione; C. T. Supuran (1999). Carbonic anhydrase inhibitors. Water-soluble, topically effective intraocular pressure lowering agents derived from isonicotinic acid and aromatic/heterocyclic sulfonamides: is the tail more important than the ring?. JOURNAL OF ENZYME INHIBITION, vol. 14, pp. 457-474, ISSN:8755-5093

  G. Mincione; L. Menabuoni; F. Briganti; F. Mincione; A. Scozzafava; C. T. Supuran (1999). Carbonic anhydrase inhibitors. Part 79. Synthesis of topically acting sulfonamides incorporating GABA moieties in their molecule, with long-lasting intraocular pressure-lowering properties.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 9, pp. 185-199, ISSN:0928-0987

  C. T. Supuran; A. Scozzafava; L. Menabuoni; F. Mincione; F. Briganti; G. Mincione (1999). Carbonic Anhydrase Inhibitors Part 72 Synthesis and Antiglaucoma Properties of Metal Complexes of p-Fluorobenzolamide.. METAL-BASED DRUGS, vol. 6, pp. 67-73, ISSN:0793-0291

  C. Guran;M. Barboiu;P. Diaconescu;V. Iluc;M. Bojin;A. Scozzafava;C. T. Supuran (1998). Synthesis and antifungal activity of metal complexes containing dichloro-tetramorpholino-cyclophosphazatriene.. METAL-BASED DRUGS, vol. 5, pp. 287-294, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  A. Scozzafava;C. T. Supuran (1998). Carbonic anhydrase inhibitors: ureido and thioureido derivatives of aromatic sulfonamides possessing increased affinities for isozyme I. A novel route to 2,5-disubstituted-1,3,4-thiadiazoles via thioureas, and their interaction with isozymes I, II and IV.. JOURNAL OF ENZYME INHIBITION, vol. 13, pp. 103-123, ISSN:8755-5093

  F. Mincione; L. Menabuoni; F. Briganti; G. Mincione; A. Scozzafava; C. T. Supuran (1998). Carbonic anhydrase inhibitors: inhibition of isozymes I, II and IV with N-hydroxysulfonamides--a novel class of intraocular pressure lowering agents.. JOURNAL OF ENZYME INHIBITION, vol. 13, pp. 267-284, ISSN:8755-5093

  A. Scozzafava;A. Nicolae;O. Maior;F. Briganti;C. T. Supuran (1998). The antifungal activity of 2,2'-diamino-4,4'-dithiazole derivatives is due to the possible inhibition of lanosterol-14-alpha-demethylase.. JOURNAL OF ENZYME INHIBITION, vol. 14, pp. 49-68, ISSN:8755-5093

  C. T. Supuran;A. Scozzafava;F. Briganti;M. A. Ilies;A. Jitianu (1998). Carbonic Anhydrase Inhibitors. Part 55 Metal Complexes of 1,3,4-Thiadiazole-2-Sulfonamide Derivatives: In Vitro Inhibition Studies With Carbonic Anhydrase Isozymes I, II and IV.. METAL-BASED DRUGS, vol. 5, pp. 103-114, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  C. T. Supuran; A. Scozzafava; F. Briganti; G. Loloiu; O. Maior (1998). Sulfonylamido derivatives of 2-aminophenoxathiin-10,10-dioxide and related compounds possess antifungal action due to the possible inhibition of lanosterol-14-alpha-demethylase.. JOURNAL OF ENZYME INHIBITION, vol. 13, pp. 291-310, ISSN:8755-5093

  C. T. Supuran;A. Scozzafava;I. Saramet;M. D. Banciu (1998). Carbonic anhydrase inhibitors: inhibition of isozymes I, II and IV with heterocyclic mercaptans, sulfenamides, sulfonamides and their metal complexes.. JOURNAL OF ENZYME INHIBITION, vol. 13, pp. 177-194, ISSN:8755-5093

  A. Scozzafava;C. T. Supuran (1998). Carbonic anhydrase inhibitors: novel compounds containing S-NH moieties: sulfenamido-sulfonamides, sulfenimido-sulfonamides and their interaction with isozymes I, II and IV.. JOURNAL OF ENZYME INHIBITION, vol. 13, pp. 419-442, ISSN:8755-5093

  A. Scozzafava;C. Cavazza;C. T. Supuran;I. Saramet;F. Briganti;M. D. Banciu (1998). Complexes with biologically active ligands. Part 11. Synthesis and carbonic anhydrase inhibitory activity of metal complexes of 4,5-disubstituted-3-mercapto-1,2,4-triazole derivatives.. METAL-BASED DRUGS, vol. 5, pp. 11-18, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  Supuran CT; Conroy CW; Maren TH. (1997). Is cyanate a carbonic anhydrase substrate?. PROTEINS, pp. 272-278, ISSN:0887-3585

  G. Mincione;A. Scozzafava;C. T. Supuran (1997). Carbonic Anhydrase Inhibitors. Part 46 Inhibition of Carbonic Anhydrase Isozymes I, II and IV With Trifluoromethylsulfonamide Derivatives and Their Zinc(II) and Copper(II) Complexes.. METAL-BASED DRUGS, vol. 4, pp. 27-34, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  C. T. Supuran;A. Scozzafava (1997). Novel aromatic/heterocyclic sulfonamides and their metal complexes as inhibitors of carbonic anhydrase isozymes I, II and IV.. JOURNAL OF ENZYME INHIBITION, vol. 12, pp. 37-51, ISSN:8755-5093

  F. Briganti;S. Mangani;P. Orioli;A. Scozzafava;G. Vernaglione;C. T. Supuran (1997). Carbonic anhydrase activators: X-ray crystallographic and spectroscopic investigations for the interaction of isozymes I and II with histamine.. BIOCHEMISTRY, vol. 36, pp. 10384-10392, ISSN:0006-2960 DOI   Accesso ONLINE all'editore

  A. Jitianu;M. A. Llies;F. Briganti;A. Scozzafava;C. T. Supuran (1997). Complexes with biologically active ligands. Part 9 metal complexes of 5-benzoylamino- and 5-(3-nitrobenzoyl-amino)-1,3,4-thiadiazole-2-sulfonamide as carbonic anhydrase inhibitors.. METAL-BASED DRUGS, vol. 4, pp. 1-7, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  C. T. Supuran;A. Scozzafava;A. Jitianu (1997). Carbonic anhydrase inhibitors. Part 54: metal complexes of heterocyclic sulfonamides: a new class of antiglaucoma agents.. METAL-BASED DRUGS, vol. 4, pp. 307-315, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  A. Scozzafava;C. T. Supuran (1997). Complexes With Biologically Active Ligands. Part 10 Inhibition of Carbonic Anhydrase Isozymes I and II With Metal Complexes of Imidazo[2,1-b ]-1,3,4-Thiadiazole-2-Sulfonamide.. METAL-BASED DRUGS, vol. 4, pp. 19-26, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  F. Briganti;A. Scozzafava;C. T. Supuran (1997). Carbonic Anhydrase Activators. Part 19 Spectroscopic and Kinetic Investigations for the Interaction of Isozymes I and II With Primary Amines.. METAL-BASED DRUGS, vol. 4, pp. 221-227, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  C. T. Supuran;F. Briganti;A. Scozzafava (1997). Sulfenamido-sulfonamides as inhibitors of carbonic anhydrase isozymes I, II and IV.. JOURNAL OF ENZYME INHIBITION, vol. 12, pp. 175-190, ISSN:8755-5093

  C. T. Supuran (1996). Complexes with biologically active ligands. Part 4. Coordination compounds of chlorothiazide with transition metal ions behave as strong carbonic anhydrase inhibitors.. METAL-BASED DRUGS, vol. 3, pp. 79-83, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  M. Barboiu;M. Cimpoesu;C. Guran;C. T. Supuran (1996). 1,3,4-thiadiazole derivatives. Part 9. Synthesis and biological activity of metal complexes of 5-(2-aminoethyl)-2-amino-1,3,4-thiadiazole.. METAL-BASED DRUGS, vol. 3, pp. 227-232, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  C. T. Supuran (1996). Complexes With Biologically Active Ligands. Part 2. Preparation of Copper(II) Complexes of Positively-Charged Derivatives of Aminoglutethimide.. METAL-BASED DRUGS, vol. 3, pp. 57-62, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  F. Briganti; R. Pierattelli; A. Scozzafava; C.T. Supuran (1996). Carbonic anhydrase inhibitors .37. Novel classes of isozyme I and II inhibitors and their mechanism of action. Kinetic and spectroscopic investigations on native and cobalt-substituted enzymes. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 31, pp. 1001-1010, ISSN:0223-5234

  S. L. Sumalan;J. Casanova;G. Alzuet;J. Borrás;A. Castiñeiras;C. T. Supuran (1996). Synthesis and characterization of metal(II)-8-quinolinsulfonamidato (sa-) complexes (M = Co, Ni, Cu, and Zn). Crystal structure of [Zn(sa)2(NH3)]NH3 complex. Carbonic anhydrase inhibitory properties.. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 62, pp. 31-39, ISSN:0162-0134

  J. Borràs;J. Casanova;T. Cristea;A. Gheorghe;A. Scozzafava;C. T. Supuran;V. Tudor (1996). Complexes With Biologically Active Ligands. Part 6 Ni(II) Coordination Compounds of Hydrazine and Heterocyclic Sulfonamides as Inhibitors of the Zinc Enzyme Carbonic Anhydrase.. METAL-BASED DRUGS, vol. 3, pp. 143-148, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  F. Briganti; R.Pierattelli; A.Scozzafava; C.T.Supuran (1996). Carbonic anhydrase inhibitors. Part 37#. Novel classes of isozymes I and II inhibitors and their mechanism of action. Kinetic and spectroscopic investigations on the native and cobalt-substituted enzymes. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 31, pp. 1001-1010, ISSN:0223-5234

  C. T. Supuran (1996). Complexes with biologically active ligands. Part 1. Synthesis of coordination compounds of diazoxide with transition- and main-group cations.. METAL-BASED DRUGS, vol. 3, pp. 25-30, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  D. Timotheatou;P. V. Ioannou;A. Scozzafava;F. Briganti;C. T. Supuran (1996). Carbonic Anhydrase Interaction With Lipothioars Enites: A Novel Class of Isozymes I and II Inhibitors.. METAL-BASED DRUGS, vol. 3, pp. 263-268, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  C. T. Supuran;R. M. Claramunt;J. L. Lavandera;J. Elguero (1996). Carbonic anhydrase activators. XV. A kinetic study of the interaction of bovine isozyme II with pyrazoles, bis- and tris-azolyl-methanes.. BIOLOGICAL & PHARMACEUTICAL BULLETIN, vol. 19, pp. 1417-1422, ISSN:0918-6158

  M. Barboiu;C. Guran;I. Jitaru;M. Cimpoesu;C. T. Supuran (1996). Complexes With Biologically Active Ligands. Part 7 Synthesis and Fungitoxic Activity of Metal Complexes Containing 1,3,5-tris-(8-Hydroxyquinolino)- Trichlorocyclo-Triphosphazatriene.. METAL-BASED DRUGS, vol. 3, pp. 233-240, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  C. T. Supuran (1995). Metal Complexes of 1,3,4-Thiadiazole-2,5-Disulfonamide are Strong Dual Carbonic Anhydrase Inhibitors, although the Ligand Possesses very Weak such Properties.. METAL-BASED DRUGS, vol. 2, pp. 331-336, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  C. T. Supuran (1995). Thienothiopyransulfonamides as complexing agents for the preparation of dual carbonic anhydrase inhibitors.. METAL-BASED DRUGS, vol. 2, pp. 327-330, ISSN:0793-0291 DOI   Accesso ONLINE all'editore

  B. W. Clare;C. T. Supuran (1994). Carbonic anhydrase activators. 3: structure-activity correlations for a series of isozyme II activators.. JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 83, pp. 768-773, ISSN:0022-3549

  C. T. Supuran;G. Manole;M. Andruh (1993). Carbonic anhydrase inhibitors. Part 11. Coordination compounds of heterocyclic sulfonamides with lanthanides are potent inhibitors of isozymes I and II.. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 49, pp. 97-103, ISSN:0162-0134

  C. T. Supuran;A. T. Balaban;P. Cabildo;R. M. Claramunt;J. L. Lavandera;J. Elguero (1993). Carbonic anhydrase activators. VII. Isozyme II activation by bisazolyl-methanes, -ethanes and related azoles.. BIOLOGICAL & PHARMACEUTICAL BULLETIN, vol. 16, pp. 1236-1239, ISSN:0918-6158

  C. T. Supuran;G. Manole;A. Dinculescu;A. Schiketanz;M. D. Gheorghiu;I. Puscas;A. T. Balaban (1992). Carbonic anhydrase inhibitors. V: Pyrylium salts in the synthesis of isozyme-specific inhibitors.. JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 81, pp. 716-719, ISSN:0022-3549