Moreno LELLI

Ruolo attuale:: Professore Associato
SSD:: CHIM/03 - Chimica generale ed inorganica
Afferenza organizzativa:: Dipartimento di Chimica 'Ugo Schiff' - DICUS

Recapiti

	0554574259 - 0554573001
	moreno.lelli(AT)unifi.it

Moreno LELLI

Orario di ricevimento (aggiornato al 20/09/2021)

Giovedì mattina dalle 11h15 alle 13h15 presso il mio ufficio al CERM.

Via Luigi Sacconi 6, 50019 Sesto Fiorentino (FI).

é fortemente consigliato prendere un appuntamento prima per telefono o per mail, indicando nell'oggetto "Ricevimento"

Moreno LELLI

Biografia

Prof. Moreno LELLI

Nato a Bologna il 13 Dicembre 1975

Ufficio:

Dipartimento di Chimica "Ugo Schiff", Via della Lastruccia 3 50019 Sesto Fiorentino (FI)

Centro Risonanze Magnetiche Dell'Università di Firenze (CERM), Via Luigi Sacconi 6 50019 Sesto Fiorentino (FI)

Tel: +39 055 457 4259

@-mail: moreno.lelli(at)unifi.it

Moreno LELLI

Curriculum

CARRIERA ACCADEMICA

2016-presente Università di Firenze (Professore Associato)

2009-2015 École Normale Supérieure de Lyon

Posizione permanente di ricerca CNRS all’ École Normale Supérieure di Lione (Ingénieur de Recherche (IR-2)) con incarico di insegnamento.

2007-2009 Post-doc FIRB presso il CERM (Univerità di Firenze).

2003-2006 Assegno di Ricerca dell’Università di Firenze presso il Dipartimento di Chimica ugo schiff dell'Università di Firenze.

ISTRUZIONE ACCADEMICA

2000-2002 Corso di Perfezionamento (Ph.D) in Chimica alla Scuola Normale Superiore di Pisa.

Supervisori Prof. Piero Salvadori e Prof. Lorenzo Di Bari. Tesi: “Solution Structure and Solution Dynamics in Chiral Ytterbium(III) Complexes” Votazione: 70/70 con lode.

1994-1999 Scuola Normale Superiore di Pisa

2000 Diploma in Chimica della Scuola Normale Superiore of Pisa. Votazione: summa cum laude. Tesi: “ Trivalent lanthanide complexes in asymmetric catalysis ”

Novembre 1999. Laurea (Master Degree) in Chimica presso la Facoltà di Scienze M.F.N. dell’Università di Pisa. Valutazione: 110/110 e lode. Supervisore: Dott. Lorenzo Di Bari. Tesi: “Complessi chirali di itterbio (III) come ausiliari in stereochimica organica ”.

Moreno LELLI

Interessi

Ricerca in Risonanza Magnetica in genere ed NMR di stato solido in particolare.

Applicazioni dello stato solido allo studio dei materiali, e delle biomolecole.

Dynamic Nuclear Polarization (DNP) NMR applicato allo studio dei materiali e biomolecole.

Moreno LELLI

Pubblicazioni

Legenda

Contributo su rivista |

Articolo su libro |

Libro |

Contributo in atti di convegno (proceeding) |

Brevetto |

Curatela | Altro

Altro |

Tesi di Dottorato

Jiafei Mao; Xinsheng Jin; Man Shi; David Heidenreich; Lynda J. Brown; Richard C. D. Brown; Moreno Lelli; Xiao He; Clemens Glaubitz (2024). Molecular mechanisms and evolutionary robustness of a color switch in proteorhodopsins. SCIENCE ADVANCES, vol. 10, pp. eadj0384-eadj0384, ISSN:2375-2548 DOI Accesso ONLINE all'editore

Wan Z.; Shi M.; Gong Y.; Lucci M.; Li J.; Zhou J.; Yang X.-L.; Lelli M.; He X.; Mao J. (2024). Multitasking Pharmacophores Support Cabotegravir-Based Long-Acting HIV Pre-Exposure Prophylaxis (PrEP). MOLECULES, vol. 29, pp. 376-376, ISSN:1420-3049 DOI Accesso ONLINE all'editore

Bellomo, Giovanni; Paciotti, Silvia; Concha-Marambio, Luis; Rizzo, Domenico; Wojdaƚa, Anna Lidia; Chiasserini, Davide; Gatticchi, Leonardo; Cerofolini, Linda; Giuntini, Stefano; De Luca, Chiara Maria Giulia; Ma, Yihua; Farris, Carly M; Pieraccini, Giuseppe; Bologna, Sara; Filidei, Marta; Ravera, Enrico; Lelli, Moreno; Moda, Fabio; Fragai, Marco; Parnetti, Lucilla; Luchinat, Claudio (2023). Cerebrospinal fluid lipoproteins inhibit α-synuclein aggregation by interacting with oligomeric species in seed amplification assays. MOLECULAR NEURODEGENERATION, vol. 18, pp. 1-24, ISSN:1750-1326 DOI Accesso ONLINE all'editore

Federico De Biasi; Michael A. Hope; Claudia E. Avalos; Ganesan Karthikeyan; Gilles Casano; Aditya Mishra; Saumya Badoni; Gabriele Stevanato; Dominik J. Kubicki; Jonas Milani; Jean-Philippe Ansermet; Aaron Rossini; Moreno Lelli; Olivier Ouari; Lyndon Emsley (2023). Optically Enhanced Solid-State 1H NMR Spectroscopy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 145, pp. 14874-14883, ISSN:0002-7863 DOI

Hutchison M.-T.; Bellomo G.; Cherepanov A.; Stirnal E.; Furtig B.; Richter C.; Linhard V.; Gurewitsch E.; Lelli M.; Morgner N.; Schrader T.; Schwalbe H. (2023). Modulation of Aβ42 Aggregation Kinetics and Pathway by Low-Molecular-Weight Inhibitors. CHEMBIOCHEM, vol. 24, pp. 202200760-202200760, ISSN:1439-4227 DOI Accesso ONLINE all'editore

Shukla R.; Peoples A.J.; Ludwig K.C.; Maity S.; Derks M.G.N.; De Benedetti S.; Krueger A.M.; Vermeulen B.J.A.; Harbig T.; Lavore F.; Kumar R.; Honorato R.V.; Grein F.; Nieselt K.; Liu Y.; Bonvin A.M.J.J.; Baldus M.; Kubitscheck U.; Breukink E.; Achorn C.; Nitti A.; Schwalen C.J.; Spoering A.L.; Ling L.L.; Hughes D.; Lelli M.; Roos W.H.; Lewis K.; Schneider T.; Weingarth M. (2023). An antibiotic from an uncultured bacterium binds to an immutable target. CELL, vol. 186, pp. 4059-4073, ISSN:0092-8674 DOI

Chamignon C.; Lelli M.; Emsley J.W.; Luckhurst G.R.; Zimmermann H. (2023). Proton-decoupled deuterium NMR study of an asymmetric liquid crystal dimer having two nematic phases. PHYSICAL REVIEW. E, vol. 108, pp. 024702-1-024702-9, ISSN:2470-0045 DOI Accesso ONLINE all'editore

Tricomi, Jacopo; Cacaci, Margherita; Biagiotti, Giacomo; Caselli, Lucrezia; Niccoli, Lorenzo; Torelli, Riccardo; Gabbani, Alessio; Di Vito, Maura; Pineider, Francesco; Severi, Mirko; Sanguinetti, Maurizio; Menna, Enzo; Lelli, Moreno; Berti, Debora; Cicchi, Stefano; Bugli, Francesca; Richichi, Barbara (2022). Ball milled glyco-graphene oxide conjugates markedly disrupted Pseudomonas aeruginosa biofilms. NANOSCALE, vol. 14, pp. 10190-10199, ISSN:2040-3364 DOI

Berruyer, Pierrick; Bertarello, Andrea; Björgvinsdóttir, Snædís; Lelli, Moreno; Emsley, Lyndon (2022). 1H Detected Relayed Dynamic Nuclear Polarization. JOURNAL OF PHYSICAL CHEMISTRY. C, vol. 126, pp. 7564-7570, ISSN:1932-7447 DOI

Alessio Milanesi, Moreno Lelli, Fulvio Ratto, Sonia Centi (2022). Development of Plasmonic Goldnanorods stabilized with PEG and MBT, and included in Biocompatible PVA/Chitosan Hydrogels for Applications in Wound Healing Monitoring (COMUNICATION). pp. 0-0, in Book of Abstracts - 1st PiCSU Symposium

Shukla, Rhythm; Lavore, Francesca; Maity, Sourav; Derks, Maik G N; Jones, Chelsea R; Vermeulen, Bram J A; Melcrová, Adéla; Morris, Michael A; Becker, Lea Marie; Wang, Xiaoqi; Kumar, Raj; Medeiros-Silva, João; van Beekveld, Roy A M; Bonvin, Alexandre M J J; Lorent, Joseph H; Lelli, Moreno; Nowick, James S; MacGillavry, Harold D; Peoples, Aaron J; Spoering, Amy L; Ling, Losee L; Hughes, Dallas E; Roos, Wouter H; Breukink, Eefjan; Lewis, Kim; Weingarth, Markus (2022). Teixobactin kills bacteria by a two-pronged attack on the cell envelope. NATURE, vol. 608, pp. 390-396, ISSN:0028-0836 DOI

Alessio Milanesi, Moreno Lelli, Fulvio Ratto, Sonia Centi (2022). Development of Plasmonic Goldnanorods stabilized with PEG and MBT, and included in Biocompatible PVA/Chitosan Hydrogels for Applications in Wound Healing Monitoring. In: 1st PiCSU (PhD in Chemical Sciences at UniFI) Symposium 2022, Sesto Fiorentino (Florence), Italy, 19-21/01/2022, PhD Course in Chemical Sciences at University of Florence, pp. 0-0.

Monu Kaushik; Hugo Lingua; Gabriele Stevanato; Margarita Elokova; Moreno Lelli; Anne Lesage; Olivier Ouari (2022). Trehalose matrices for high temperature dynamic nuclear polarization enhanced solid state NMR. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, vol. 24, pp. 12167-12175, ISSN:1463-9076 DOI

Alessio Milanesi, Moreno Lelli, Giada Magni, Claudia Borri, Fulvio Ratto, Sonia Centi, Lucia Cavigli, Roberto Pini, Boris Khlebtsov (2022). Biomimetic Systems containing Smooth and Rough Goldnanorods for Biomedical Sensing via Photoacoustic Stimulation. ELSEVIER, vol. SSRN eJournal (Social Science Research Network Electronic Journal), pp. 0-0, ISSN:0922-3444 Accesso ONLINE all'editore

Jabbour, Ribal; Renom-Carrasco, Marc; Chan, Ka Wing; Völker, Laura; Berruyer, Pierrick; Wang, Zhuoran; Widdifield, Cory M; Lelli, Moreno; Gajan, David; Copéret, Christophe; Thieuleux, Chloé; Lesage, Anne (2022). Multiple Surface Site Three-Dimensional Structure Determination of a Supported Molecular Catalyst. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 144, pp. 10270-10281, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Menzildjian G.; Lund A.; Yulikov M.; Gajan D.; Niccoli L.; Karthikeyan G.; Casano G.; Jeschke G.; Ouari O.; Lelli M.; Lesage A. (2021). Efficient Dynamic Nuclear Polarization up to 230 K with Hybrid BDPA-Nitroxide Radicals at a High Magnetic Field. JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL, vol. 125, pp. 13329-13338, ISSN:1520-6106 DOI Accesso ONLINE all'editore

Vilona D.; Lelli M.; Dumont E.; Lacote E. (2021). Organo-Polyoxometalate-Based Hydrogen-Bond Catalysis. CHEMISTRY-A EUROPEAN JOURNAL, vol. 27, pp. 17761-17764, ISSN:0947-6539 DOI Accesso ONLINE all'editore

Hope M.A.; Bjorgvinsdottir S.; Halat D.M.; Menzildjian G.; Wang Z.; Zhang B.; Macmanus-Driscoll J.L.; Lesage A.; Lelli M.; Emsley L.; Grey C.P. (2021). Endogenous 17O Dynamic Nuclear Polarization of Gd-Doped CeO2from 100 to 370 K. JOURNAL OF PHYSICAL CHEMISTRY. C, vol. 125, pp. 18799-18809, ISSN:1932-7447 DOI Accesso ONLINE all'editore

Odermatt N.T.; Lelli M.; Herrmann T.; Abriata L.A.; Japaridze A.; Voilquin H.; Singh R.; Piton J.; Emsley L.; Dietler G.; Cole S.T. (2020). Structural and DNA binding properties of mycobacterial integration host factor mIHF. JOURNAL OF STRUCTURAL BIOLOGY, vol. 209, pp. 107434-107434, ISSN:1047-8477 DOI

Lucia Banci, Letizia Barbieri, Vito Calderone, Francesca Cantini, Linda Cerofolini, Simone Ciofi-Baffoni, Isabella C. Felli, Marco Fragai, Moreno Lelli, Claudio Luchinat, Enrico Luchinat, Giacomo Parigi, Mario Piccioli, Roberta Pierattelli, Enrico Ravera, Antonio Rosato, Leonardo Tenori, Paola Turano (2020). Biomolecular NMR at 1.2 GHz. Accesso ONLINE all'editore

Stevanato G.; Casano G.; Kubicki D.J.; Rao Y.; Hofer L.E.; Menzildjian G.; Karoui H.; Siri D.; Cordova M.; Yulikov M.; Jeschke G.; Lelli M.; Lesage A.; Ouari O.; Emsley L. (2020). Open and closed radicals: Local geometry around unpaired electrons governs magic-angle spinning dynamic nuclear polarization performance. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 142, pp. 16587-16599, ISSN:0002-7863 DOI

Imrie C.T.; Paterson D.A.; Storey J.M.D.; Chamignon C.; Lelli M.; Emsley J.W.; Luckhurst G.R. (2020). Phase transitions in a high magnetic field of an odd, symmetric liquid crystal dimer having two nematic phases, N U and NTB, studied by NMR spectroscopy. PHYSICAL REVIEW. E, vol. 102, pp. 042706-042706, ISSN:2470-0045 DOI

Berruyer P.; Bjorgvinsdottir S.; Bertarello A.; Stevanato G.; Rao Y.; Karthikeyan G.; Casano G.; Ouari O.; Lelli M.; Reiter C.; Engelke F.; Emsley L. (2020). Dynamic Nuclear Polarization Enhancement of 200 at 21.15 T Enabled by 65 kHz Magic Angle Spinning. THE JOURNAL OF PHYSICAL CHEMISTRY LETTERS, vol. 11, pp. 8386-8391, ISSN:1948-7185 DOI

Avalos C.E.; Richert S.; Socie E.; Karthikeyan G.; Casano G.; Stevanato G.; Kubicki D.J.; Moser J.E.; Timmel C.R.; Lelli M.; Rossini A.J.; Ouari O.; Emsley L. (2020). Enhanced Intersystem Crossing and Transient Electron Spin Polarization in a Photoexcited Pentacene-Trityl Radical. JOURNAL OF PHYSICAL CHEMISTRY. A, MOLECULES, SPECTROSCOPY, KINETICS, ENVIRONMENT, & GENERAL THEORY, vol. 124, pp. 6068-6075, ISSN:1089-5639 DOI

Shukla R.; Medeiros-Silva J.; Parmar A.; Vermeulen B.J.A.; Das S.; Paioni A.L.; Jekhmane S.; Lorent J.; Bonvin A.M.J.J.; Baldus M.; Lelli M.; Veldhuizen E.J.A.; Breukink E.; Singh I.; Weingarth M. (2020). Mode of action of teixobactins in cellular membranes. NATURE COMMUNICATIONS, vol. 11, pp. 2848-2858, ISSN:2041-1723 DOI

Lund A.; Casano G.; Menzildjian G.; Kaushik M.; Stevanato G.; Yulikov M.; Jabbour R.; Wisser D.; Renom-Carrasco M.; Thieuleux C.; Bernada F.; Karoui H.; Siri D.; Rosay M.; Sergeyev I.V.; Gajan D.; Lelli M.; Emsley L.; Ouari O.; Lesage A. (2020). TinyPols: A family of water-soluble binitroxides tailored for dynamic nuclear polarization enhanced NMR spectroscopy at 18.8 and 21.1 T. CHEMICAL SCIENCE, vol. 11, pp. 2810-2818, ISSN:2041-6520 DOI

Lelli, Moreno; Di Bari, Lorenzo (2019). Solution structure and structural rearrangement in chiral dimeric ytterbium(iii) complexes determined by paramagnetic NMR and NIR-CD. DALTON TRANSACTIONS, vol. 48, pp. 882-890, ISSN:1477-9234 DOI Accesso ONLINE all'editore

Viger-Gravel J.; Avalos C.E.; Kubicki D.J.; Gajan D.; Lelli M.; Ouari O.; Lesage A.; Emsley L. (2019). 19F Magic Angle Spinning Dynamic Nuclear Polarization Enhanced NMR Spectroscopy. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 58 (22), pp. 7249-7253, ISSN:1433-7851, Wiley-VCH Verlag: DOI Accesso ONLINE all'editore

Wisser, Dorothea; Karthikeyan, Ganesan; Lund, Alicia; Casano, Gilles; Karoui, Hakim; Yulikov, Maxim; Menzildjian, Georges; Pinon, Arthur C.; Purea, Armin; Engelke, Frank; Chaudhari, Sachin R.; Kubicki, Dominik; Rossini, Aaron J.; Moroz, Ilia B.; Gajan, David; Copéret, Christophe; Jeschke, Gunnar; Lelli, Moreno; Emsley, Lyndon; Lesage, Anne; Ouari, Olivier (2018). BDPA-Nitroxide Biradicals Tailored for Efficient Dynamic Nuclear Polarization Enhanced Solid-State NMR at Magnetic Fields up to 21.1 T. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 140, pp. 13340-13349, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Emsley, J W; Lelli, M; Luckhurst, G R; Zimmermann, H (2018). Publisher's Note: ^13C NMR study of the director distribution adopted by the modulated nematic phases formed by liquid-crystal dimers with odd numbers of atoms in their spacers [Phys. Rev. E 96, 062702 (2017)]. PHYSICAL REVIEW. E, vol. 97, pp. 029903-029903, ISSN:2470-0045 DOI

Sturlese, Mattia; Manta, Bruno; Bertarello, Andrea; Bonilla, Mariana; Lelli, Moreno; Zambelli, Barbara; Grunberg, Karin; Mammi, Stefano; Comini, Marcelo A.; Bellanda, Massimo* (2018). The lineage-specific, intrinsically disordered N-terminal extension of monothiol glutaredoxin 1 from trypanosomes contains a regulatory region. SCIENTIFIC REPORTS, vol. 8, pp. 13716-13716, ISSN:2045-2322 DOI Accesso ONLINE all'editore

Bellomo G, Bologna S, Gonnelli L, Ravera E, Fragai M, Lelli M, Luchinat C (2018). Aggregation kinetics of the Aβ1-40 peptide monitored by NMR. CHEMICAL COMMUNICATIONS, vol. 54, pp. 7601-7604, ISSN:1359-7345 DOI Accesso ONLINE all'editore

Chaudhari, Sachin R.; Wisser, Dorothea; Pinon, Arthur C.; Berruyer, Pierrick; Gajan, David; Tordo, Paul; Ouari, Olivier; Reiter, Christian; Engelke, Frank; Copéret, Christophe; Lelli, Moreno*; Lesage, Anne; Emsley, Lyndon (2017). Dynamic Nuclear Polarization Efficiency Increased by Very Fast Magic Angle Spinning. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 139, pp. 10609-10612, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Berruyer, Pierrick; Lelli, Moreno; Conley, Matthew P; Silverio, Daniel L; Widdifield, Cory M; Siddiqi, Georges; Gajan, David; Lesage, Anne; Copéret, Christophe; Emsley, Lyndon (2017). Three-Dimensional Structure Determination of Surface Sites. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 139, pp. 849-855, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Birkou, Maria; Chasapis, Christos T.; Marousis, Konstantinos D.; Loutsidou, Ariadni K.; Bentrop, Detlef; Lelli, Moreno; Herrmann, Torsten; Carthy, Jonathon M.; Episkopou, Vasso*; Spyroulias, Georgios A. (2017). A Residue Specific Insight into the Arkadia E3 Ubiquitin Ligase Activity and Conformational Plasticity. JOURNAL OF MOLECULAR BIOLOGY, vol. 429, pp. 2373-2386, ISSN:0022-2836 DOI Accesso ONLINE all'editore

Jarvis, J.A.; Haies, I.; Lelli, M.; Rossini, A.J.; Kuprov, I.; Carravetta, M.; Williamson, P.T.F.* (2017). Measurement of 14N quadrupole couplings in biomolecular solids using indirect-detection 14N solid-state NMR with DNP. CHEMICAL COMMUNICATIONS, vol. 53, pp. 12116-12119, ISSN:1359-7345 DOI Accesso ONLINE all'editore

Emsley, J.W.; Lelli, M.; Luckhurst, G.R.; Zimmermann, H. (2017). C 13 NMR study of the director distribution adopted by the modulated nematic phases formed by liquid-crystal dimers with odd numbers of atoms in their spacers. PHYSICAL REVIEW. E, vol. 96, pp. 062702-062702, ISSN:2470-0045 DOI Accesso ONLINE all'editore

Vilona, Debora; Lachkar, David; Dumont, Elise*; Lelli, Moreno; Lacôte, Emmanuel (2017). Elucidation of the Conformation of Polyglycine Organo-Polyoxotungstates: Evidence for Zipper Folding. CHEMISTRY-A EUROPEAN JOURNAL, vol. 23, pp. 13323-13327, ISSN:0947-6539 DOI Accesso ONLINE all'editore

Pinon, Arthur C.; Schlagnitweit, Judith; Berruyer, Pierrick; Rossini, Aaron J.; Lelli, Moreno; Socie, Etienne; Tang, Mingxue; Pham, Tran; Lesage, Anne; Schantz, Staffan; Emsley, Lyndon* (2017). Measuring Nano- to Microstructures from Relayed Dynamic Nuclear Polarization NMR. JOURNAL OF PHYSICAL CHEMISTRY. C, vol. 121, pp. 15993-16005, ISSN:1932-7447 DOI Accesso ONLINE all'editore

Lachkar, David; Vilona, Debora; Dumont, Elise; Lelli, Moreno; Lacôte, Emmanuel (2016). Grafting of Secondary Diolamides onto [P2W15V3O62]9- Generates Hybrid Heteropoly Acids. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 55, pp. 5961-5965, ISSN:1433-7851 DOI Accesso ONLINE all'editore

Pucheta-Martinez, Encarna; D'Amelio, Nicola; Lelli, Moreno; Martinez-Torrecuadrada, Jorge L.; Sudol, Marius; Saladino, Giorgio; Gervasio, Francesco Luigi (2016). Changes in the folding landscape of the WW domain provide a molecular mechanism for an inherited genetic syndrome. SCIENTIFIC REPORTS, vol. 6, pp. 30293-30300, ISSN:2045-2322 DOI Accesso ONLINE all'editore

Morando, Maria Agnese; Saladino, Giorgio; D'Amelio, Nicola; Pucheta-Martinez, Encarna; Lovera, Silvia; Lelli, Moreno; López-Méndez, Blanca; Marenchino, Marco; Campos-Olivas, Ramón; Gervasio, Francesco Luigi (2016). Conformational Selection and Induced Fit Mechanisms in the Binding of an Anticancer Drug to the c-Src Kinase. SCIENTIFIC REPORTS, vol. 6, pp. 24439-24448, ISSN:2045-2322 DOI Accesso ONLINE all'editore

Chaudhari, Sachin R.; Berruyer, Pierrick; Gajan, David; Reiter, Christian; Engelke, Frank; Silverio, Daniel L.; Copéret, Christophe; Lelli, Moreno; Lesage, Anne; Emsley, Lyndon (2016). Dynamic nuclear polarization at 40 kHz magic angle spinning. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, vol. 18, pp. 10616-10622, ISSN:1463-9076 DOI Accesso ONLINE all'editore

Emsley, J.W; Lelli, M.; Joy, H.; Tamba, M.-G.; Mehl, G.H. (2016). Similarities and differences between molecular order in the nematic and twist-bend nematic phases of a symmetric liquid crystal dimer. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, vol. 18, pp. 9419-9430, ISSN:1463-9076 DOI Accesso ONLINE all'editore

Pucheta-Martínez, Encarna; Saladino, Giorgio; Morando, Maria Agnese; Martinez-Torrecuadrada, Jorge; Lelli, Moreno; Sutto, Ludovico; D'Amelio, Nicola; Gervasio, Francesco Luigi (2016). An allosteric cross-talk between the activation loop and the ATP binding site regulates the activation of Src kinase. SCIENTIFIC REPORTS, vol. 6, pp. 24235-24241, ISSN:2045-2322 DOI Accesso ONLINE all'editore

Heist, L.M; Poon, C.-D.; Samulski, E.T.; Photinos, D.J.; Jokisaari, J.; Vaara, J.; Emsley, J.W.; Mamone, S.; Lelli, M. (2015). Benzene at 1 GHz. Magnetic field-induced fine structure. JOURNAL OF MAGNETIC RESONANCE, vol. 258, pp. 17-24, ISSN:1090-7807 DOI Accesso ONLINE all'editore

Sturlese, Mattia; Lelli, Moreno; Manta, Bruno; Mammi, Stefano; Comini, Marcelo A.; Bellanda, Massimo (2015). 1H, 13C and 15N resonance assignment of the mature form of monothiol glutaredoxin 1 from the pathogen Trypanosoma brucei. BIOMOLECULAR NMR ASSIGNMENTS, vol. 9, pp. 143-146, ISSN:1874-2718 DOI Accesso ONLINE all'editore

Lelli, Moreno; Chaudhari, Sachin R.; Gajan, David; Casano, Gilles; Rossini, Aaron J.; Ouari, Olivier; Tordo, Paul; Lesage, Anne; Emsley, Lyndon (2015). Solid-State Dynamic Nuclear Polarization at 9.4 and 18.8 T from 100 K to Room Temperature. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 137, pp. 14558-14561, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Huang, Yongqi; Yoon, Mi-Kyung; Otieno, Steve; Lelli, Moreno; Kriwacki, Richard W. (2015). The activity and stability of the intrinsically disordered Cip/Kip protein family are regulated by non-receptor tyrosine kinases. JOURNAL OF MOLECULAR BIOLOGY, vol. 427, pp. 371-386, ISSN:0022-2836 DOI Accesso ONLINE all'editore

Ceccon, Alberto; Lelli, Moreno; D'Onofrio, Mariapina; Molinari, Henriette; Assfalg, Michael (2014). Dynamics of a globular protein adsorbed to liposomal nanoparticles. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 136, pp. 13158-13161, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Domenici, Valentina; Lelli, Moreno; Cifelli, Mario; Hamplova, Vera; Marchetti, Alessandro; Veracini, Carlo Alberto (2014). Conformational properties and orientational order of a de Vries liquid crystal investigated through NMR spectroscopy. CHEMPHYSCHEM, vol. 15, pp. 1485-1495, ISSN:1439-4235 DOI Accesso ONLINE all'editore

Rossini, Aaron J.; Widdifield, Cory M.; Zagdoun, Alexandre; Lelli, Moreno; Schwarzwälder, Martin; Copéret, Christophe; Lesage, Anne; Emsley, Lyndon (2014). Dynamic nuclear polarization enhanced NMR spectroscopy for pharmaceutical formulations. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 136, pp. 2324-2334, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Lelli, Moreno; Rossini, Aaron J.; Casano, Gilles; Ouari, Olivier; Tordo, Paul; Lesage, Anne; Emsley, Lyndon (2014). Hydrophobic radicals embedded in neutral surfactants for dynamic nuclear polarization of aqueous environments at 9.4 Tesla. CHEMICAL COMMUNICATIONS, vol. 50, pp. 10198-10201, ISSN:1359-7345 DOI Accesso ONLINE all'editore

De Biasio, Alfredo; Ibáñez De Opakua, Alain; Cordeiro, Tiago N.; Villate, Maider; Merino, Nekane; Sibille, Nathalie; Lelli, Moreno; Diercks, Tammo; Bernadó, Pau; Blanco, Francisco J. (2014). P15PAF Is an intrinsically disordered protein with nonrandom structural preferences at sites of interaction with other proteins. BIOPHYSICAL JOURNAL, vol. 106, pp. 865-874, ISSN:0006-3495 DOI

Gajan, David; Schwarzwälder, Martin; Conley, Matthew P.; Grüning, Wolfram R.; Rossini, Aaron J.; Zagdoun, Alexandre; Lelli, Moreno; Yulikov, Maxim; Jeschke, Gunnar; Sauvée, Claire; Ouari, Olivier; Tordo, Paul; Veyre, Laurent; Lesage, Anne; Thieuleux, Chloé; Emsley, Lyndon; Copéret, Christophe (2013). Solid-phase polarization matrixes for dynamic nuclear polarization from homogeneously distributed radicals in mesostructured hybrid silica materials. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 135, pp. 15459-15466, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Conley, Matthew P.; Drost, Ruben M.; Baffert, Mathieu; Gajan, David; Elsevier, Cornelis; Franks, W. Trent; Oschkinat, Hartmut; Veyre, Laurent; Zagdoun, Alexandre; Rossini, Aaron; Lelli, Moreno; Lesage, Anne; Casano, Gilles; Ouari, Olivier; Tordo, Paul; Emsley, Lyndon; Copéret, Christophe; Thieuleux, Chloé (2013). A well-defined Pd hybrid material for the Z-selective semihydrogenation of alkynes characterized at the molecular level by DNP SENS. CHEMISTRY-A EUROPEAN JOURNAL, vol. 19, pp. 12234-12238, ISSN:0947-6539 DOI Accesso ONLINE all'editore

King, John; Shammas, Christos; Nareen, Misbah; Lelli, Moreno; Ramesh, Vasudevan (2013). NMR characterisation of a highly conserved secondary structural RNA motif of Halobacterium halobium 23S rRNA. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 11, pp. 3382-3392, ISSN:1477-0520 DOI Accesso ONLINE all'editore

Telitel, Sofia; Schweizer, Stéphane; Morlet-Savary, Fabrice; Graff, Bernadette; Tschamber, Théophile; Blanchard, Nicolas; Fouassier, Jean Pierre; Lelli, Moreno; Lacoîte, Emmanuel; Lalevée, Jacques (2013). Soft photopolymerizations initiated by dye-sensitized formation of NHC-boryl radicals under visible light. MACROMOLECULES, vol. 46, pp. 43-48, ISSN:0024-9297 DOI Accesso ONLINE all'editore

Zagdoun, Alexandre; Rossini, Aaron J.; Conley, Matthew P.; Grüning, Wolfram R.; Schwarzwälder, Martin; Lelli, Moreno; Franks, W. Trent; Oschkinat, Hartmut; Copéret, Christophe; Emsley, Lyndon; Lesage, Anne (2013). Improved dynamic nuclear polarization surface-enhanced NMR spectroscopy through controlled incorporation of deuterated functional groups. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 52, pp. 1222-1225, ISSN:1433-7851 DOI Accesso ONLINE all'editore

Samantaray, Manoja K.; Alauzun, Johan; Gajan, David; Kavitake, Santosh; Mehdi, Ahmad; Veyre, Laurent; Lelli, Moreno; Lesage, Anne; Emsley, Lyndon; Copéret, Christophe; Thieuleux, Chloé (2013). Evidence for metal-surface interactions and their role in stabilizing Well-defined immobilized Ru-NHC alkene metathesis catalysts. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 135, pp. 3193-3199, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Liu, Miao; Chen, Ping; Véricel, Evelyne; Lelli, Moreno; Béguin, Laetitia; Lagarde, Michel; Guichardant, Michel (2013). Characterization and biological effects of di-hydroxylated compounds deriving from the lipoxygenation of ALA. JOURNAL OF LIPID RESEARCH, vol. 54, pp. 2083-2094, ISSN:0022-2275 DOI Accesso ONLINE all'editore

Rossini, Aaron J.; Zagdoun, Alexandre; Lelli, Moreno; Lesage, Anne; Copéret, Christophe; Emsley, Lyndon (2013). Dynamic nuclear polarization surface enhanced NMR spectroscopy. ACCOUNTS OF CHEMICAL RESEARCH, vol. 46, pp. 1942-1951, ISSN:0001-4842 DOI Accesso ONLINE all'editore

Emsley, James W; Lelli, Moreno; Lesage, Anne; Luckhurst, Geoffrey R. (2013). A comparison of the conformational distributions of the achiral symmetric liquid crystal dimer CB7CB in the achiral nematic and chiral twist-bend nematic phases. JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL, vol. 117, pp. 6547-6557, ISSN:1520-6106 DOI Accesso ONLINE all'editore

Rossini, Aaron J.; Zagdoun, Alexandre; Lelli, Moreno; Canivet, Jérôme; Aguado, Sonia; Ouari, Olivier; Tordo, Paul; Rosay, Melanie; Maas, Werner E.; Copéret, Christophe; Farrusseng, David; Emsley, Lyndon; Lesage, Anne (2012). Dynamic nuclear polarization enhanced solid-state NMR spectroscopy of functionalized metal-organic frameworks. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 51, pp. 123-127, ISSN:1433-7851 DOI Accesso ONLINE all'editore

Domenici, Valentina; Cifelli, Mario; Marchetti, Alessandro; Lelli, Moreno; Hamplova, Vera; Kaspar, Miroslav; Veracini, Carlo Alberto (2012). Smectic A-smectic C* transition in a de vries liquid crystal by 2H NMR. MOLECULAR CRYSTALS AND LIQUID CRYSTALS, vol. 553, pp. 103-110, ISSN:1542-1406 DOI Accesso ONLINE all'editore

Zagdoun, Alexandre; Rossini, Aaron J.; Gajan, David; Bourdolle, Adrien; Ouari, Olivier; Rosay, Melanie; Maas, Werner E.; Tordo, Paul; Lelli, Moreno; Emsley, Lyndon; Lesage, Anne; Copéret, Christophe (2012). Non-aqueous solvents for DNP surface enhanced NMR spectroscopy. CHEMICAL COMMUNICATIONS, vol. 48, pp. 654-656, ISSN:1359-7345 DOI Accesso ONLINE all'editore

Beguin, Laetitia; Emsley, James W; Lelli, Moreno; Lesage, Anne; Luckhurst, Geoffrey R.; Timimi, Bakir A.; Zimmermann, Herbert (2012). The chirality of a twist-bend nematic phase identified by NMR spectroscopy. JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL, vol. 116, pp. 7940-7951, ISSN:1520-6106 DOI Accesso ONLINE all'editore

Rossini, Aaron J.; Zagdoun, Alexandre; Lelli, Moreno; Gajan, David; Rascón, Fernando; Rosay, Melanie; Maas, Werner E.; Copéret, Christophe; Lesage, Anne; Emsley, Lyndon (2012). One hundred fold overall sensitivity enhancements for Silicon-29 NMR spectroscopy of surfaces by dynamic nuclear polarization with CPMG acquisition. CHEMICAL SCIENCE, vol. 3, pp. 108-115, ISSN:2041-6520 DOI Accesso ONLINE all'editore

Beguin, Laetitia; Emsley, James W.; Lelli, Moreno; Lesage, Anne; Luckhurst, Geoffrey R.; Timimi, Bakir A.; Zimmermann, Herbert (2012). Erratum: The chirality of a twist-bend nematic phase identified by NMR spectroscopy (Journal of Physical Chemistry B (2012) 116 (7940-7951) DOI: 10.1021/jp302705n). JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL, vol. 116, pp. 10407-10407, ISSN:1520-6106 DOI Accesso ONLINE all'editore

Zagdoun, Alexandre; Casano, Gilles; Ouari, Olivier; Lapadula, Giuseppe; Rossini, Aaron J.; Lelli, Moreno; Baffert, Mathieu; Gajan, David; Veyre, Laurent; Maas, Werner E.; Rosay, Melanie; Weber, Ralph T.; Thieuleux, Chloé; Coperet, Christophe; Lesage, Anne; Tordo, Paul; Emsley, Lyndon (2012). A slowly relaxing rigid biradical for efficient dynamic nuclear polarization surface-enhanced NMR spectroscopy: Expeditious characterization of functional group manipulation in hybrid materials. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 134, pp. 2284-2291, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Vitzthum, Veronika; Miéville, Pascal; Carnevale, Diego; Caporini, Marc A.; Gajan, David; Copéret, Christophe; Lelli, Moreno; Zagdoun, Alexandre; Rossini, Aaron J.; Lesage, Anne; Emsley, Lyndon; Bodenhausen, Geoffrey (2012). Dynamic nuclear polarization of quadrupolar nuclei using cross polarization from protons: Surface-enhanced aluminium-27 NMR. CHEMICAL COMMUNICATIONS, vol. 48, pp. 1988-1990, ISSN:1359-7345 DOI Accesso ONLINE all'editore

L.Banci; I.Bertini; O.Blazevits; F.Cantini; M.Lelli; C.Luchinat; J.Mao; M.Vieru (2011). NMR Characterization of a “Fibril-Ready” State ofDemetalated Wild-Type Superoxide Dismutase. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 133 (2), pp. 345-349, ISSN:0002-7863 DOI

Lelli, Moreno; Gajan, David; Lesage, Anne; Caporini, Marc A.; Vitzthum, Veronika; Miéville, Pascal; Héroguel, Florent; Rascón, Fernando; Roussey, Arthur; Thieuleux, Chloé; Boualleg, Malika; Veyre, Laurent; Bodenhausen, Geoffrey; Copéret, Christophe; Emsley, Lyndon (2011). Fast characterization of functionalized silica materials by silicon-29 surface-enhanced NMR spectroscopy using dynamic nuclear polarization. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 133, pp. 2104-2107, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Lesage, Anne; Lelli, Moreno; Gajan, David; Caporini, Marc A.; Vitzthum, Veronika; Miéville, Pascal; Alauzun, Johan; Roussey, Arthur; Thieuleux, Chloé; Mehdi, Ahmad; Bodenhausen, Geoffrey; Copéret, Christophe; Emsley, Lyndon (2010). Surface enhanced NMR spectroscopy by dynamic nuclear polarization. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 132, pp. 15459-15461, ISSN:0002-7863 DOI Accesso ONLINE all'editore

I.Bertini; L.Emsley; M.Lelli; C.Luchinat; J.Mao; G.Pintacuda (2010). Ultrafast MAS solid-state NMR permits extensive 13C and 1H detection in paramagnetic metalloproteins. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 132, pp. 5558-5559, ISSN:0002-7863 DOI

I.Bertini; A.Bhaumik; G.De Paëpe; R.G.Griffin; M.Lelli; J.R.Lewandowski; C.Luchinat (2010). High-resolution solid-state NMR structure of a 17.6 kDa protein. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 132(3), pp. 1032-1040, ISSN:0002-7863 DOI

Marchetti, Alessandro; Domenici, Valentina; Novotna, Vladimira; Lelli, Moreno; Cifelli, Mario; Lesage, Anne; Veracini, Carlo A. (2010). Direct Measure of the Tilt Angle in de Vries-Type Liquid Crystals through NMR Spectroscopy. CHEMPHYSCHEM, vol. 11, pp. 1641-1645, ISSN:1439-4235 DOI Accesso ONLINE all'editore

Moreno, Lelli (2009). Solution Structure and Solution Dynamics in Chiral Ytterbium(III) Complexes. Pisa: Edizioni della Normale, Scuola Normale Superiore di Pisa, Pisa., ISBN:978-88-7642-349-9

S. Balayssac; I. Bertini; A. Bhaumik; M. Lelli; C. Luchinat (2008). Paramagnetic shifts in solid-state NMR of proteins to elicit structural information. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 105, pp. 17284-17289, ISSN:0027-8424 DOI

Lelli, Moreno; Bari, Lorenzo Di; Salvadori, Piero (2007). Solution study of chiral 1,2-diol Yb3+ chelates through near-IR circular dichroism. TETRAHEDRON-ASYMMETRY, vol. 18, pp. 2876-2885, ISSN:0957-4166 DOI Accesso ONLINE all'editore

S.Balayssac; I.Bertini; M.Lelli; C.Luchinat; M.Maletta (2007). Paramagnetic ions provide structural restraints in solid-state NMR of proteins. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 129, pp. 2218-2219, ISSN:0002-7863, American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671: DOI

S. Balayssac; I. Bertini; K. Falber; M. Fragai; S. Jehle; M. Lelli; C. Luchinat; H. Oschkinat; K. J. Yeo (2007). Solid-state NMR of matrix metalloproteinase 12: An approach complementary to solution NMR. CHEMBIOCHEM, vol. 8, pp. 486-489, ISSN:1439-4227 DOI Accesso ONLINE all'editore

E. Babini; I.C. Felli; M. Lelli; C. Luchinat; R. Pierattelli (2005). Backbone and side-chains 1H, 13C and 15N NMR assignment of human beta-parvalbumin. JOURNAL OF BIOMOLECULAR NMR, vol. 33, pp. 137-137, ISSN:0925-2738, Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254: DOI

Lelli, Moreno; Pintacuda, Guido; Cuzzola, Angela; Di Bari, Lorenzo (2005). Monitoring proton dissociation and solution conformation of chiral ytterbium complexes with near-IR CD. CHIRALITY, vol. 17, pp. 201-211, ISSN:0899-0042 DOI Accesso ONLINE all'editore

Di Bari, Lorenzo; Lelli, Moreno; Salvadori, Piero (2004). Ligand lability and chirality inversion in Yb heterobimetallic catalysts. CHEMISTRY-A EUROPEAN JOURNAL, vol. 10, pp. 4594-4598, ISSN:0947-6539 DOI Accesso ONLINE all'editore

E.Babini; I.Bertini; F.Capozzi; I.C.Felli; M.Lelli; C.Luchinat (2004). Direct carbon detection in paramagnetic metalloproteins to further exploit pseudocontact shift restraints. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 126, pp. 10496-10497, ISSN:0002-7863 DOI

Di Bari, Lorenzo; Lelli, Moreno; Pintacuda, Guido; Pescitelli, Gennaro; Marchetti, Fabio; Salvadori, Piero (2003). Solution versus solid-state structure of ytterbium heterobimetallic catalysts. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 125, pp. 5549-5558, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Bari, Lorenzo Di; Lelli, Moreno; Pintacuda, Guido; Salvadori, Piero (2002). Yb(fod)3 in the spectroscopic determination of the configuration of chiral diols: A survey of the lanthanide diketonate method. CHIRALITY, vol. 14, pp. 265-273, ISSN:0899-0042 DOI Accesso ONLINE all'editore

Moreno LELLI

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Moreno LELLI

Biography

Born in Bologna on 13 Dicembre 1975

Office:

Chemistry Department "Ugo Schiff" of the University of Florence,

Via della Lastruccia 3

50019 Sesto Fiorentino (FI)

Magnetic Resonance Centre (CERM),

Via Luigi Sacconi 6 50019 Sesto Fiorentino (FI)

Tel: +39 055 457 4259

@-mail: moreno.lelli(at)unifi.it

Moreno LELLI

Curriculum

Academic Career

2016- University of Florence (Associate Professor)

2009-2015 École Normale Supérieure de Lyon Research CNRS permanent position (IR-2) with teaching.

2007-2009 Post-doc FIRB at CERM (Centre of Magnetic Resonance, CERM) (University of Florence).

2003-2006 Post-Doc at University of Florence at the Chemistry Department

Education

2000-2002 PhD in Chemistry at Scuola Normale Superiore of Pisa

1994-1999 Scuola Normale Superiore of Pisa (Bachelor and Master degrees)

1994-1999 University of Pisa (Bachelor and Master degrees)

Moreno LELLI

Interest

Research interest on Magnetic Resonance in Chemistry. In particular Solid-state NMR (ssNMR) and Dynamic Nuclear Polarization.

Application of DNP and ssNMR to the characterization of materials and biomolecules.

Moreno LELLI

Moreno LELLI

Moreno LELLI

Moreno LELLI

Moreno LELLI

Moreno LELLI

Moreno LELLI

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