Isabella Caterina FELLI

Ruolo attuale:: Professore Associato
SSD:: CHIM/03 - Chimica generale ed inorganica
Afferenza organizzativa:: Dipartimento di Chimica 'Ugo Schiff' - DICUS

Recapiti

	0554574242
	isabellacaterina.felli(AT)unifi.it

Ulteriori Recapiti

	CERM, Via L. Sacconi 6, 50019 Sesto Fiorentino
	http://www.cerm.unifi.it/people/isabella-c-felli

Isabella Caterina FELLI

Orario di ricevimento (aggiornato al 29/05/2013) lunedi' e giovedi' alle 2.30

Isabella Caterina FELLI

Biografia Isabella C. Felli si e’ laureata in Chimica nel 1994 ed ha ottenuto il Dottorato in Chimica nel 1998 all’universita’ di Firenze sotto la guida del Prof. Ivano Bertini. Ha svolto attivita' di ricerca nel gruppo del Prof. Geoffrey Bodenhausen nel 1996 al NHMFL a Tallahasse (USA). Ha ottenuto una borsa di studio dell’associazione Alexander von Humboldt per un post-dottorato all’universita’ di Francoforte con il Prof. Christian Griesinger (1998-1999). In questo periodo ha inoltre ottenuto varie grants (Marie Curie, DAAD, EMBO) e alcuni premi (premio Federchimica per la Tesi di Laurea, premio della Societa' Chimica Italiana per la Tesi di Dottorato). Successivamente e’ ritornata a Firenze nel gruppo del Prof. Ivano Bertini dove ha continutato la sua attivita’ di ricerca e dove ha iniziato l’attivita’ di insegnamento. Dal 2005 e’ professore associato (CHIM/03) all’Universita’ di Firenze. E' membro del del Collegio dei Docenti del Dottorato in Chimica e del del Dottorato Internazionale in Biologia Strutturale (Universita' di Fiernze). Dal 2006 e' stata coinvolta come "local operator" in progetti EC (EUNMR, EASTNMR, BioNMR) mirati a fornire accesso da utenti europei alla infrastruttura di ricerca NMR. Coordina una Marie Curie Initial Training Network (ITN) "High resolution tools to understand the functional role of protein intrinsic disorder" (IDPbyNMR, 8 partner, 3.4 M, data di inizio 01/11/2012, durata 4 years). E' stata invitata a molti convegni internazionali come speaker (alcuni esempi recenti includono ICMRBS 2012, ISMAR 2013, EUROMAR 2013). Il suo interesse principale consiste nello sviluppo di metodi NMR innovativi per lo studio di metalloproteine, di macromolecole biologiche e delle loro interazioni con gli ioni metallici.

Isabella Caterina FELLI

Curriculum Isabella Caterina Felli
Nata a Charlottesville, Virginia, USA

dal 01/11/2005
Professore Associato (CHIM/03), Università degli Studi di FIRENZE, Dipartimento di CHIMICA "Ugo Schiff"

Dal 05/2001 al 10/2005
Professore a contratto della Facoltà di SMFN, Università di Firenze.
Titolare del corso di Chimica degli Alimenti (CHIM/03, 6 CFU) del Corso di Laurea in Chimica Applicata (AA 2001/2002 Corso di Diploma Universitario in Chimica).
Coordinamento e supporto alla didattica (Manager Didattico) nell'ambito del Corso di Laurea in Chimica Applicata (AA 2001/2002 Corso di Diploma Universitario in Chimica).

Dal 03/1999 al 04/2001
Assegno di Ricerca, Dipartimento di Chimica, Università di Firenze.
"Studi NMR di metalloproteine paramagnetiche" (responsabile scientifico Prof. Ivano Bertini).

Dal 04/1998 al 11/1998
Post-doc Alexander von Humboldt, Università di Francoforte, Germania.
"Sviluppo di nuovi metodi NMR" (responsabile scientifico Prof. Christian Griesinger).

Dal 11/ 1997 al 03/1998 e dal 11/1998 al 02/1999
Borsa di studio del Dipartimento di Chimica, Università di Firenze.
"NMR di metalloproteine paramagnetiche" (responsabile scientifico Prof. Ivano Bertini).

Dal 04/1996 al 09/1996
Borsa di studio del National High Magnetic Field Laboratory (NHMFL), Tallahassee, Florida, USA.
"Sviluppo di nuovi metodi NMR per determinare le proprietà dinamiche di metalloproteine paramagnetiche in soluzione mediante lo studio di fenomeni di cross-correlazione" (responsabile scientifico Prof. Geoffrey Bodenhausen).

Dal 11/1994 al 10/1997
Dottorato di Ricerca in Scienze Chimiche (X ciclo)
"From electron and nuclear spins to the structure and dynamics of paramagnetic metalloproteins involved in electron transfer". Tutore del Dottorato: Prof. Ivano Bertini.

Dal 03/1993 al 05/1993
Borsa di studio della CRUI (Progetto Vigoni), Universität Saarlandes, Homburg, Germania.
"Applicazione della spettroscopia di risonanza magnetica elettronica in onda continua e ad impulsi (EPR ed ESEEM) allo studio di metalloproteine paramagnetiche" (responsabile scientifico Prof. Jurgen Huttermann).

Dal 05/1994 al 10/1994
Borsa di studio Bruker Spectrospin Italiana S.r.l. - Dipartimento di Chimica, Università di Firenze
"Sviluppo di tecniche strumentali per lo studio di metalloproteine paramagnetiche" (responsabile
scientifico Prof. Ivano Bertini).

Il 04/1994 - Tesi di Laurea
"Dallo studio ESEEM della superossido dismutasi alla struttura in soluzione, via NMR, di una proteina ferro-zolfo ad alto potenziale". Relatore: Prof. Ivano Bertini.

Attività di ricerca
Sviluppo di nuovi metodi basati sulla spettroscopia NMR per lo studio di metalloproteine paramagnetiche e, più in generale, di macromolecole biologiche e delle loro interazioni con gli ioni metallici.
I principali risultati includono: 1) la determinazione della prima struttura tridimensionale di una metalloproteina paramagnetica in soluzione tramite NMR (tesi di laurea), seguita da altri esempi e dallo sviluppo della relativa metodologia, 2) lo sviluppo di nuovi metodi NMR per la determinazione della mobilità locale, 3) lo sviluppo di nuovi metodi NMR basati sulla 13C per lo studio di proteine, 4) lo sviluppo di nuovi metodi NMR allo stato solido, 5) lo sviluppo di nuovi metodi NMR per lo studio di proteine intrinsecamente disordinate (IDP).
I risultati scientifici ottenuti, descritti in 80 pubblicazioni (e in ulteriori 2 inviate per la pubblicazione), sono stati presentati a molti convegni internazionali (32 presentazioni orali su invito, 41 come poster).

Attività didattica, settore CHIM/03, presso la Facoltà di Scienze Matematiche Fisiche e Naturali, Università di Firenze

AA 2011/2012 - oggi
Corso di Laurea Magistrale SCIENZE CHIMICHE
Corso di NMR IN BIOLOGIA STRUTTURALE (6 CFU)
AA 2010/2011
Corso di Laurea Magistrale SCIENZE CHIMICHE
Corso di LABORATORIO DI GENOMICA STRUTTURALE INORGANICA (6 CFU)
AA 2009/2010 - oggi
Corso di Laurea Magistrale SCIENZE CHIMICHE
Corso di METODI SPETTROSCOPICI DI INDAGINE IN CHIMICA INORGANICA (6 CFU)
AA 2009/2010 - AA 2010/2011
Corso di Laurea CHIMICA
Corso di SPETTROSCOPIA NMR (6 CFU)
AA 2008/2009
Corso di Laurea Specialistica CHIMICA
Corso di METODI SPETTROSCOPICI E RISONANZA MAGNETICA, Modulo II (3 CFU)
AA 2006/2007 AA 2010/2011
Corso di Laurea CHIMICA
Corso di METODI FISICI IN CHIMICA INORGANICA (6 CFU)
AA 2005/2006 AA 2009/2010
Corso di Laurea Specialistica CHIMICA DELLE MOLECOLE BIOLOGICHE
Corso di GENOMICA STRUTTURALE INORGANICA (6 CFU)
AA 2001/2002 AA 2007/2008
Corso di Laurea CHIMICA APPLICATA
Corso di CHIMICA DEGLI ALIMENTI (6 CFU) (nel 2001 Corso di Diploma Universitario in Chimica)

Attività didattica nell'ambito del Corso di Dottorato Dottorato Internazionale in Biologia Strutturale, Università di Firenze
dal 2002 al 2009 un corso per anno intitolato "Improving the NMR culture

Titoli
Responsabilità scientifica per progetti di ricerca internazionali e nazionali, ammessi al finanziamento sulla base di bandi competitivi che prevedano la revisione tra pari (progetto, durata in mesi, ruolo ricoperto):

IDPbyNMR, Marie Curie Initial Training Network, EC contract number 264257, FP7, 48 Coordinatore
BioNMR, Combination of CP and CSA, EC contract number 261863, FP7, 48 Local Operator
EASTNMR, Combination of CP and CSA, EC contract number 228461, FP7, 48 Local Operator
EUNMR, Integrated Infrastructure Initiative I3, contract number RII3-026145, FP7, 48 Local Operator

Partecipazione a comitati editoriali di riviste, collane editoriali, enciclopedie e trattati di riconosciuto prestigio (tipo, titolo, periodo):

Riviste - ChemPhysChem - editore per un numero della rivista dedicato all'NMR - in corso 08/2012 09/2013
Collane editoriali - Advances in Experimental Medicine and Biology series - editore di un volume - in corso 07/2012

Attribuzione di incarichi di ricerca (fellowship) ufficiale presso atenei e istituti di ricerca, esteri e internazionali, di alta qualificazione (tipo, ente, periodo):

Alexander von Humboldt fellowship, University of Frankfurt, Germany 04/1998 11/1998
National High Magnetic Field Laboratory (NHMFL) fellowship, FL, USA 04/1996 09/1996
Borsa di studio CRUI (Progetto Vigoni), Universität Saarlandes, Homburg, Germania 03/1993 05/1993

partecipazione ad accademie aventi prestigio nel settore (accademia, periodo):

AMPERE Group, Member of the AMPERE Committee dal 07/2010
Alexander von Humboldt Foundation, Member dal 04/1998
Marie Curie Fellows Association, Member dal 07/1998

Conseguimento di premi e riconoscimenti per l'attività scientifica:

1999 Premio di Dottorato della Società Chimica Italiana, Divisione di Chimica Inorganica per la migliore Tesi di Dottorato del X ciclo
1995 Premio Nazionale Federchimica "Federchimica - Per un futuro intelligente" per la Tesi di Laurea
1986 Viaggio premio a Strasburgo " 50 giovani al parlamento europeo", organizzato dal movimento federalista europeo, per visitare il Parlamento Europeo

1998 Vincitrice delle seguenti fellowships competitive:
Alexander von Humboldt fellowship
Marie Curie Research Training Grant ERB4001GT974957 TMR program
EMBO (European Molecular Biology Organization) Short term fellowship
DAAD (Deutscher Akademischer Austauschdienst) Research scholarship

altri titoli
Comunicazioni a congressi scientifici internazionali e scuole specializzate:
3 inviti a presentare una lecture nel 2013 (di cui una plenaria)
34 presentazioni orali su invito
41 presentazioni poster.

Organizzazione di congressi scientifici internazionali:
12 come organizzatrice, 3 come parte del comitato organizzatore.

Reviewer per le seguenti riviste scientifiche internazionali:
Journal of the American Chemical Society, Journal of Biomolecular NMR, PLoS ONE

Tutore di 4 studenti di dottorato (1 concluso, 3 in corso).
Relatore di 4 Tesi di Laurea Specialistica in Chimica, di 15 Tesi di Laurea Triennale in Chimica e Chimica Applicata, e di 5 Stage di Diploma Universitario in Chimica.

Membro del Collegio dei Docenti del Dottorato in Chimica.
Membro del Collegio dei Docenti del Dottorato Internazionale in Biologia Strutturale.

Coinvolta in progetti FIRB e PRIN coordinati dal Prof. I. Bertini o dalla Prof. Banci (PRIN09 "Biologia strutturale meccanicistica: avanzamenti metodologici e biologici" - 2009FAKHZT, PRIN 2007 "Gli ioni metallici nelle interazioni proteina-proteina" - 2007M5MWM9, PRIN-COFIN 2005 "Genomica strutturale di metalloproteine e delle loro interazioni funzionali" 2005039878, COFIN 2003 "Il ruolo degli ioni metallici nei processi metabolici" 2003035772_001, FIRB PROTEOMICA "Rete Nazionale per lo studio della Proteomica Umana (Italian Human ProteomeNet)" MIUR-RBRN07BMCT, MIUR-FIRB (Fondo per gli Investimenti della Ricerca di Base) "Piattaforme NMR per lo studio dell'interazione proteine-leganti di interesse farmacologico" - MIUR-RBLA032ZM7).

Abilitata alla professione del chimico.

Isabella Caterina FELLI

Interessi NMR, proteine, windsurf

Isabella Caterina FELLI

Pubblicazioni

Legenda

Contributo su rivista |

Articolo su libro |

Libro |

Contributo in atti di convegno (proceeding) |

Brevetto |

Curatela | Altro

Altro |

Tesi di Dottorato

Schiavina, Marco; Konrat, Ruth; Ceccolini, Irene; Mateos, Borja; Konrat, Robert; Felli, Isabella C.; Pierattelli, Roberta (2023). Studies of proline conformational dynamics in IDPs by 13C-detected cross-correlated NMR relaxation. JOURNAL OF MAGNETIC RESONANCE, vol. 354, pp. 0-0, ISSN:1090-7807 DOI Accesso ONLINE all'editore

Mészáros, Bálint; Hatos, András; Palopoli, Nicolas; Quaglia, Federica; Salladini, Edoardo; Van Roey, Kim; Arthanari, Haribabu; Dosztányi, Zsuzsanna; Felli, Isabella C; Fischer, Patrick D; Hoch, Jeffrey C; Jeffries, Cy M; Longhi, Sonia; Maiani, Emiliano; Orchard, Sandra; Pancsa, Rita; Papaleo, Elena; Pierattelli, Roberta; Piovesan, Damiano; Pritisanac, Iva; Tenorio, Luiggi; Viennet, Thibault; Tompa, Peter; Vranken, Wim; Tosatto, Silvio C E; Davey, Norman E (2023). Minimum information guidelines for experiments structurally characterizing intrinsically disordered protein regions. NATURE METHODS, pp. 0-0, ISSN:1548-7091 DOI

Pontoriero L.; Schiavina M.; Korn S.M.; Schlundt A.; Pierattelli R.; Felli I.C. (2022). NMR Reveals Specific Tracts within the Intrinsically Disordered Regions of the SARS-CoV-2 Nucleocapsid Protein Involved in RNA Encountering. BIOMOLECULES, vol. 12, pp. 929-941, ISSN:2218-273X DOI

Marco Schiavina; Letizia Pontoriero; Giuseppe Tagliaferro; Roberta Pierattelli; Isabella C. Felli (2022). The Role of Disordered Regions in Orchestrating the Properties of Multidomain Proteins: The SARS-CoV-2 Nucleocapsid Protein and Its Interaction with Enoxaparin. BIOMOLECULES, vol. 12, pp. 1302-1323, ISSN:2218-273X DOI Accesso ONLINE all'editore

Felli, Isabella C; Pierattelli, Roberta (2022). 13C Direct Detected NMR for Challenging Systems. CHEMICAL REVIEWS, vol. 122, pp. 9468-9496, ISSN:0009-2665 DOI Accesso ONLINE all'editore

Letizia Pontoriero, Marco Schiavina, Sophie M. Korn, Andreas Schlundt, Roberta Pierattelli, Isabella C. Felli (2022). "NMR reveals specific tracts within the intrinsically disordered regions of the SARS-CoV-2 Nucleocapsid protein involved in RNA encountering"- PiCSU 2022. In: PiCSU2022, Anna Maria Papini, Martina Vizza, Gina Elena Giacomazzo, Saul Santini, Marco Bonechi, Mert Acar, Davide Ranieri, Mariagrazia Lettieri, Debora Pratesi, pp. 64-64.

Berg, Hannes; Wirtz Martin, Maria A; Altincekic, Nadide; Alshamleh, Islam; Kaur Bains, Jasleen; Blechar, Julius; Ceylan, Betül; de Jesus, Vanessa; Dhamotharan, Karthikeyan; Fuks, Christin; Gande, Santosh L; Hargittay, Bruno; Hohmann, Katharina F; Hutchinson, Marie T; Korn, Sophie Marianne; Krishnathas, Robin; Kutz, Felicitas; Linhard, Verena; Matzel, Tobias; Meiser, Nathalie; Niesteruk, Anna; Pyper, Dennis J; Schulte, Linda; Trucks, Sven; Azzaoui, Kamal; Blommers, Marcel J J; Gadiya, Yojana; Karki, Reagon; Zaliani, Andrea; Gribbon, Philip; Almeida, Marcius da Silva; Anobom, Cristiane Dinis; Bula, Anna Lina; Buetikofer, Matthias; Caruso, Ícaro Putinhon; Felli, Isabella Caterina; Da Poian, Andrea T; de Amorim, Gisele Cardoso; Fourkiotis, Nikolaos K; Gallo, Angelo; Ghosh, Dhiman; Gomes-Neto, Francesco; Gorbatyuk, Oksana; Hao, Bing; Kurauskas, Vilius; Lecoq, Lauriane; Li, Yunfeng; Mebus-Antunes, Nathane Cunha; Mompean, Miguel; Neves-Martins, Thais Cristtina; Ninot-Pedrosa, Marti; Pinheiro, Anderson S; Pontoriero, Letizia; Pustovalova, Yulia; Riek, Roland; Robertson, Angus; Abi Saad, Marie Jose; Treviño, Miguel A; Tsika, Aikaterini C; Almeida, Fabio C L; Bax, Ad; Henzler-Wildman, Katherine; Hoch, Jeffrey C; Jaudzems, Kristaps; Laurents, Douglas V; Orts, Julien; Pierattelli, Roberta; Spyroulias, Georgios A; Duchardt-Ferner, Elke; Ferner, Jan; Fuertig, Boris; Hengesbach, Martin; Löhr, Frank; Qureshi, Nusrat; Richter, Christian; Saxena, Krishna; Schlundt, Andreas; Sreeramulu, Sridhar; Wacker, Anna; Weigand, Julia E; Wirmer-Bartoschek, Julia; Woehnert, Jens; Schwalbe, Harald (2022). Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development. ANGEWANDTE CHEMIE, pp. 1-13, ISSN:1521-3773 DOI

Altincekic, Nadide; Korn, Sophie Marianne; Qureshi, Nusrat Shahin; Dujardin, Marie; Ninot-Pedrosa, Martí; Abele, Rupert; Abi Saad, Marie Jose; Alfano, Caterina; Almeida, Fabio C. L.; Alshamleh, Islam; de Amorim, Gisele Cardoso; Anderson, Thomas K.; Anobom, Cristiane D.; Anorma, Chelsea; Bains, Jasleen Kaur; Bax, Adriaan; Blackledge, Martin; Blechar, Julius; Böckmann, Anja; Brigandat, Louis; Bula, Anna; Bütikofer, Matthias; Camacho-Zarco, Aldo R.; Carlomagno, Teresa; Caruso, Icaro Putinhon; Ceylan, Betül; Chaikuad, Apirat; Chu, Feixia; Cole, Laura; Crosby, Marquise G.; de Jesus, Vanessa; Dhamotharan, Karthikeyan; Felli, Isabella C.; Ferner, Jan; Fleischmann, Yanick; Fogeron, Marie-Laure; Fourkiotis, Nikolaos K.; Fuks, Christin; Fürtig, Boris; Gallo, Angelo; Gande, Santosh L.; Gerez, Juan Atilio; Ghosh, Dhiman; Gomes-Neto, Francisco; Gorbatyuk, Oksana; Guseva, Serafima; Hacker, Carolin; Häfner, Sabine; Hao, Bing; Hargittay, Bruno; Henzler-Wildman, K.; Hoch, Jeffrey C.; Hohmann, Katharina F.; Hutchison, Marie T.; Jaudzems, Kristaps; Jović, Katarina; Kaderli, Janina; Kalniņš, Gints; Kaņepe, Iveta; Kirchdoerfer, Robert N.; Kirkpatrick, John; Knapp, Stefan; Krishnathas, Robin; Kutz, Felicitas; zur Lage, Susanne; Lambertz, Roderick; Lang, Andras; Laurents, Douglas; Lecoq, Lauriane; Linhard, Verena; Löhr, Frank; Malki, Anas; Bessa, Luiza Mamigonian; Martin, Rachel W.; Matzel, Tobias; Maurin, Damien; McNutt, Seth W.; Mebus-Antunes, Nathane Cunha; Meier, Beat H.; Meiser, Nathalie; Mompeán, Miguel; Monaca, Elisa; Montserret, Roland; Mariño Perez, Laura; Moser, Celine; Muhle-Goll, Claudia; Neves-Martins, Thais Cristtina; Ni, Xiamonin; Norton-Baker, Brenna; Pierattelli, Roberta; Pontoriero, Letizia; Pustovalova, Yulia; Ohlenschläger, Oliver; Orts, Julien; Da Poian, Andrea T.; Pyper, Dennis J.; Richter, Christian; Riek, Roland; Rienstra, Chad M.; Robertson, Angus; Pinheiro, Anderson S.; Sabbatella, Raffaele; Salvi, Nicola; Saxena, Krishna; Schulte, Linda; Schiavina, Marco; Schwalbe, Harald; Silber, Mara; Almeida, Marcius da Silva; Sprague-Piercy, Marc A.; Spyroulias, Georgios A.; Sreeramulu, Sridhar; Tants, Jan-Niklas; Tārs, Kaspars; Torres, Felix; Töws, Sabrina; Treviño, Miguel Á.; Trucks, Sven; Tsika, Aikaterini C.; Varga, Krisztina; Wang, Ying; Weber, Marco E.; Weigand, Julia E.; Wiedemann, Christoph; Wirmer-Bartoschek, Julia; Wirtz Martin, Maria Alexandra; Zehnder, Johannes; Hengesbach, Martin; Schlundt, Andreas (2021). Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications. FRONTIERS IN MOLECULAR BIOSCIENCES, vol. 8, pp. 0-0, ISSN:2296-889X DOI Accesso ONLINE all'editore

Felli, Isabella C.; Bermel, Wolfgang; Pierattelli, Roberta (2021). Exclusively heteronuclear NMR experiments for the investigation of intrinsically disordered proteins: focusing on proline residues. MAGNETIC RESONANCE, vol. 2, pp. 511-522, ISSN:2699-0016 DOI

Letizia Pontoriero, Marco Schiavina, Maria Grazia Murrali, Roberta Pierattelli, Isabella Caterina Felli (2021). "Monitoring the interaction of alpha-Synuclein with Calcium Ions Through Exclusively Heteronuclear NMR Experiments" ENC 2021. In: ENC 2021 Virtual Congress, ENC organization commettee, pp. 120-120.

Pontoriero Letizia; Schiavina Marco; Murrali Maria Grazia; Pierattelli Roberta; Felli Isabella Caterina (2021). ZOOMING ON THE INTERACTION BETWEEN a-SYNUCLEIN AND CALCIUM IONS APPROACHING PHYSIOLOGICAL CONDITIONS. In: EUROMAR 2021, MARTINA LENARČIČ,ŽIVKOVIĆ MAJA MARUŠIČ, JANEZ PLAVEC, PETRA JAKSETIČ, pp. 175-175, ISBN:978-961-95442-0-4

Schiavina, Marco; Pontoriero, Letizia; Uversky, Vladimir N.; Felli, Isabella C.; Pierattelli, Roberta (2021). The highly flexible disordered regions of the SARS-CoV-2 nucleocapsid N protein within the 1–248 residue construct: sequence-specific resonance assignments through NMR. BIOMOLECULAR NMR ASSIGNMENTS, vol. 15, pp. 219-227, ISSN:1874-2718 DOI Accesso ONLINE all'editore

G. T. Heller, F. A. Aprile, T. C. T. Michaels, R. Limbocker, M. Perni, F. S. Ruggeri, B. Mannini, T. Lohr, M. Bonomi, C. Camilloni, A. De Simone, I. C. Felli, R. Pierattelli, T. P. J. Knowles, C. M. Dobson, M. Vendruscolo, (2020). Small-molecule sequestration of amyloid-beta. as a drug discovery strategy for Alzheimer's disease. SCIENCE ADVANCES, vol. 6, pp. 0-0, ISSN:2375-2548 DOI Accesso ONLINE all'editore

Lucia Banci, Letizia Barbieri, Vito Calderone, Francesca Cantini, Linda Cerofolini, Simone Ciofi-Baffoni, Isabella C. Felli, Marco Fragai, Moreno Lelli, Claudio Luchinat, Enrico Luchinat, Giacomo Parigi, Mario Piccioli, Roberta Pierattelli, Enrico Ravera, Antonio Rosato, Leonardo Tenori, Paola Turano (2020). Biomolecular NMR at 1.2 GHz. Accesso ONLINE all'editore

Mateos, Borja; Conrad-Billroth, Clara; Schiavina, Marco; Beier, Andreas; Kontaxis, Georg; Konrat, Robert; Felli, Isabella C.; Pierattelli, Roberta (2020). The ambivalent role of proline residues in an intrinsically disordered protein: from disorder promoters to compaction facilitators. JOURNAL OF MOLECULAR BIOLOGY, vol. 432, pp. 3093-3111, ISSN:0022-2836 DOI

Olsen G.L.; Szekely O.; Mateos B.; Kaderavek P.; Ferrage F.; Konrat R.; Pierattelli R.; Felli I.C.; Bodenhausen G.; Kurzbach D.; Frydman L. (2020). Sensitivity-enhanced three-dimensional and carbon-detected two-dimensional NMR of proteins using hyperpolarized water. JOURNAL OF BIOMOLECULAR NMR, vol. 74, pp. 161-171, ISSN:0925-2738 DOI

Kosol, Simone; Contreras-Martos, Sara; Piai, Alessandro; Varadi, Mihaly; Lazar, Tamas; Bekesi, Angela; Lebrun, Pierre; Felli, Isabella C; Pierattelli, Roberta; Tompa, Peter (2020). Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity. SCIENTIFIC REPORTS, vol. 10, pp. 0-0, ISSN:2045-2322 DOI

Orton, Henry W.; Stanek, Jan; Schubeis, Tobias; Foucaudeau, Dylan; Ollier, Claire; Draney, Adrian W.; Le Marchand, Tanguy; De Paepe, Diane Cala; Felli, Isabella C.; Pierattelli, Roberta; Hiller, Sebastian; Bermel, Wolfgang; Pintacuda, Guido (2020). Protein NMR resonance assignment without spectral analysis: 5D SOlid‐state Automated Projection SpectroscopY (SO‐APSY). ANGEWANDTE CHEMIE, vol. 59, pp. 2380-2384, ISSN:0044-8249 DOI Accesso ONLINE all'editore

Bertarello, Andrea; Benda, Ladislav; Sanders, Kevin; Pell, Andrew J; Knight, Michael John; Pelmenschikov, Vladimir; Gonnelli, Leonardo; Felli, Isabella Caterina; Kaupp, Martin; Emsley, Lyndon; Pierattelli, Roberta; Pintacuda, Guido (2020). Pico-meter resolution structure of the coordination sphere in the metal-binding site in a metalloprotein by NMR. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 142, pp. 16757-16765, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Marco Schiavina, Edoardo Salladini, Maria Grazia Murrali, Giancarlo Tria, Isabella Caterina Felli, Roberta Pierattelli, Sonia Longhi (2020). Ensemble description of the intrinsically disordered N-terminal domain of the Nipah virus P/V protein from combined NMR and SAXS. SCIENTIFIC REPORTS, vol. 10, pp. 0-0, ISSN:2045-2322 DOI Accesso ONLINE all'editore

Murrali M.G.; Felli I.C.; Pierattelli R. (2020). Adenoviral E1A exploits flexibility and disorder to target cellular proteins. BIOMOLECULES, vol. 10, pp. 0-0, ISSN:2218-273X DOI Accesso ONLINE all'editore

Pontoriero Letizia; Schiavina Marco; Murrali Maria Grazia; Pierattelli Roberta; Felli Isabella Caterina (2020). Monitoring the Interaction of α-Synuclein with Calcium Ions through Exclusively Heteronuclear Nuclear Magnetic Resonance Experiments. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 59, pp. 18537-18545, ISSN:1433-7851 DOI Accesso ONLINE all'editore

Bonaccorsi, Marta; Knight, Michael; Le Marchand, Tanguy; Dannatt, Hugh; Schubeis, Tobias; Salmon, Loic; Felli, Isabella; Emsley, Lyndon; Pierattelli, Roberta; Pintacuda, Guido (2020). Multimodal response to copper binding in superoxide dismutase dynamics. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 142, pp. 19660-19667, ISSN:0002-7863 DOI Accesso ONLINE all'editore

Mateos, Borja; Konrat, Robert; Pierattelli, Roberta*; Felli, Isabella C. (2019). NMR Characterization of Long-Range Contacts in Intrinsically Disordered Proteins from Paramagnetic Relaxation Enhancement in 13C Direct-Detection Experiments. CHEMBIOCHEM, vol. 20, pp. 335-339, ISSN:1439-4227 DOI Accesso ONLINE all'editore

Eftekharzadeh, Bahareh; Banduseela, Varuna C.; Chiesa, Giulio; Martínez-Cristóbal, Paula; Rauch, Jennifer N.; Nath, Samir R.; Schwarz, Daniel M. C.; Shao, Hao; Marin-Argany, Marta; Di Sanza, Claudio; Giorgetti, Elisa; Yu, Zhigang; Pierattelli, Roberta; Felli, Isabella C.; Brun-Heath, Isabelle; García, Jesús; Nebreda, Ángel R.; Gestwicki, Jason E.; Lieberman, Andrew P.; Salvatella, Xavier (2019). Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor. NATURE COMMUNICATIONS, vol. 10, pp. 0-0, ISSN:2041-1723 DOI Accesso ONLINE all'editore

Daniels, Malcolm J.; Nourse, J. Brucker; Kim, Hanna; Sainati, Valerio; Schiavina, Marco; Murrali, Maria Grazia; Pan, Buyan; Ferrie, John J.; Haney, Conor M.; Moons, Rani; Gould, Neal S.; Natalello, Antonino; Grandori, Rita; Sobott, Frank; Petersson, E. James; Rhoades, Elizabeth; Pierattelli, Roberta; Felli, Isabella; Uversky, Vladimir N.; Caldwell, Kim A.; Caldwell, Guy A.; Krol, Edward S.; Ischiropoulos, Harry (2019). Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity. SCIENTIFIC REPORTS, vol. 9, pp. 0-0, ISSN:2045-2322 DOI Accesso ONLINE all'editore

Kukic, Predrag; Lo Piccolo, Giuseppe Mattia; Oliveira Nogueira, Marcela Cristina; Svergun, Dmitri I.; Vendruscolo, Michele; Felli, Isabella C.; Pierattelli, Roberta (2019). The free energy landscape of the oncogene protein E7 of human papillomavirus type 16 reveals a complex interplay between ordered and disordered regions. SCIENTIFIC REPORTS, vol. 9, pp. 0-0, ISSN:2045-2322 DOI Accesso ONLINE all'editore

Schiavina, Marco; Murrali, Maria Grazia; Pontoriero, Letizia; Sainati, Valerio; Kümmerle, Rainer; Bermel, Wolfgang; Pierattelli, Roberta; Felli, Isabella C. (2019). Taking Simultaneous Snapshots of Intrinsically Disordered Proteins in Action. BIOPHYSICAL JOURNAL, vol. 117, pp. 46-55, ISSN:0006-3495 DOI Accesso ONLINE all'editore

Escobedo, Albert; Topal, Busra; Kunze, Micha B A; Aranda, Juan; Chiesa, Giulio; Mungianu, Daniele; Bernardo-Seisdedos, Ganeko; Eftekharzadeh, Bahareh; Gairí, Margarida; Pierattelli, Roberta; Felli, Isabella C; Diercks, Tammo; Millet, Oscar; García, Jesús; Orozco, Modesto; Crehuet, Ramon; Lindorff-Larsen, Kresten; Salvatella, Xavier (2019). Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in a transcription factor. NATURE COMMUNICATIONS, vol. 10, pp. 0-0, ISSN:2041-1723 DOI Accesso ONLINE all'editore

Davey, Norman E.; Babu, M. Madan; Blackledge, Martin; Bridge, Alan; Capella-Gutierrez, Salvador; Dosztanyi, Zsuzsanna; Drysdale, Rachel; Edwards, Richard J.; Elofsson, Arne; Felli, Isabella C.; Gibson, Toby J.; Gutmanas, Aleksandras; Hancock, John M.; Harrow, Jen; Higgins, Desmond; Jeffries, Cy M.; Le Mercier, Philippe; Mészáros, Balint; Necci, Marco; Notredame, Cedric; Orchard, Sandra; Ouzounis, Christos A.; Pancsa, Rita; Papaleo, Elena; Pierattelli, Roberta; Piovesan, Damiano; Promponas, Vasilis J.; Ruch, Patrick; Rustici, Gabriella; Romero, Pedro; Sarntivijai, Sirarat; Saunders, Gary; Schuler, Benjamin; Sharan, Malvika; Shields, Denis C.; Sussman, Joel L.; Tedds, Jonathan A.; Tompa, Peter; Turewicz, Michael; Vondrasek, Jiri; Vranken, Wim F.; Wallace, Bonnie Ann; Wichapong, Kanin; Tosatto, Silvio C. E. (2019). An intrinsically disordered proteins community for ELIXIR. F1000RESEARCH, vol. 8, pp. 0-0, ISSN:2046-1402 DOI

Szekely O, Olsen GL, Felli IC, Frydman L (2018). High-resolution 2D NMR of disordered proteins enhanced by hyperpolarized water. ANALYTICAL CHEMISTRY, pp. 0-0, ISSN:0003-2700 DOI Accesso ONLINE all'editore

Murrali, Maria Grazia; Piai, Alessandro; Bermel, Wolfgang; Felli, Isabella C.*; Pierattelli, Roberta (2018). Proline Fingerprint in Intrinsically Disordered Proteins. CHEMBIOCHEM, vol. 19, pp. 1625-1629, ISSN:1439-4227 DOI Accesso ONLINE all'editore

Murrali, Maria Grazia; Schiavina, Marco; Sainati, Valerio; Bermel, Wolfgang; Pierattelli, Roberta; Felli, Isabella C. (2018). 13C APSY-NMR for sequential assignment of intrinsically disordered proteins. JOURNAL OF BIOMOLECULAR NMR, vol. 70, pp. 167-175, ISSN:0925-2738 DOI Accesso ONLINE all'editore

Baronti, Lorenzo; Hosek, Tomas; Gil Caballero, Sergio; Raveh Amit, Hadas; Eduardo O., Calçada; Ayala, Isabel; Dinnyés, András; Felli, Isabella C.; Pierattelli, Roberta; Brutscher, Bernhard (2017). Fragment-Based NMR Study of the Conformational Dynamics in the bHLH Transcription Factor Ascl1. BIOPHYSICAL JOURNAL, vol. 112, pp. 1366-1373, ISSN:0006-3495 DOI Accesso ONLINE all'editore

Marcela Oliveira, Nogueira; Hosek, Tomas; Eduardo O., Calçada; Castiglia, Francesca; Massimi, Paola; Banks, Lawrence; Felli, Isabella C.; Pierattelli, Roberta (2017). Monitoring HPV-16 E7 phosphorylation events. VIROLOGY, vol. 503, pp. 70-75, ISSN:0042-6822 DOI Accesso ONLINE all'editore

Contreras-Martos, Sara; Piai, Alessandro; Kosol, Simone; Varadi, Mihaly; Bekesi, Angela; Lebrun, Pierre; Volkov, Alexander N.; Gevaert, Kris; Pierattelli, Roberta; Felli, Isabella C.; Tompa, Peter (2017). Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP. SCIENTIFIC REPORTS, vol. 7, pp. 0-0, ISSN:2045-2322 DOI Accesso ONLINE all'editore

Canales Á, Rösinger M, Sastre J, Felli IC, Jiménez-Barbero J, Giménez-Gallego G, Fernández-Tornero C. (2017). Hidden α-helical propensity segments within disordered regions of the transcriptional activator CHOP. PLOS ONE, vol. 12, pp. 0-0, ISSN:1932-6203 DOI Accesso ONLINE all'editore

Piai, Alessandro; Gonnelli, Leonardo; Felli, Isabella C.; Pierattelli, Roberta; Kazimierczuk, Krzysztof; Grudziaz, Katarzyna; Koźmiński, Wiktor; Zawadzka Kazimierczuk, Anna (2016). Amino acid recognition for automatic resonance assignment of intrinsically disordered proteins. JOURNAL OF BIOMOLECULAR NMR, vol. 64, pp. 239-253, ISSN:0925-2738 DOI

Piai, Alessandro; Eduardo o, Calçada; Tarenzi, Thomas; Grande, Alessandro del; Varadi, Mihaly; Tompa, Peter; Felli, ISABELLA CATERINA; Pierattelli, Roberta (2016). Just a Flexible Linker? The Structural and Dynamic Properties of CBP-ID4 Revealed by NMR Spectroscopy. BIOPHYSICAL JOURNAL, vol. 110, pp. 372-381, ISSN:0006-3495 DOI Accesso ONLINE all'editore

Hosek, Tomas; Eduardo O., Calçada; Marcela Oliveira, Nogueira; Salvi, Michele; Pagani, Talita Duarte; Felli, ISABELLA CATERINA; Pierattelli, Roberta (2016). Structural and Dynamic Characterization of the Molecular Hub Early Region 1A (E1A) from Human Adenovirus. CHEMISTRY-A EUROPEAN JOURNAL, vol. 22, pp. 13010-13013, ISSN:0947-6539 DOI Accesso ONLINE all'editore

Eftekharzadeh, Bahareh; Piai, Alessandro; Chiesa, Giulio; Mungianu, Daniele; García, Jesús; Pierattelli, Roberta; Felli, Isabella C.; Salvatella, Xavier (2016). Sequence Context Influences the Structure and Aggregation Behavior of a PolyQ Tract. BIOPHYSICAL JOURNAL, vol. 110, pp. 2361-2366, ISSN:0006-3495 DOI Accesso ONLINE all'editore

Brutscher, Bernhard; Felli, Isabella C.; Gil-Caballero, Sergio; Hošek, Tomáš; Kümmerle, Rainer; Piai, Alessandro; Pierattelli, Roberta; Sólyom, Zsófia (2015). NMR methods for the study of instrinsically disordered proteins structure, dynamics, and interactions: General overview and practical guidelines. In: Isabella C. Felli, Roberta Pierattelli. Intrinsically Dosordered Proteins Studied by NMR Spectroscopy, pp. 49-122, BERLIN, HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY: Springer, ISBN:978-3-319-20164-1. DOI Accesso ONLINE all'editore

Hošek, Tomáš; Gil-Caballero, Sergi; Pierattelli, Roberta; Brutscher, Bernhard; Felli, Isabella C. (2015). Longitudinal relaxation properties of 1HN and 1Hα determined by direct-detected 13C NMR experiments to study intrinsically disordered proteins (IDPs). JOURNAL OF MAGNETIC RESONANCE, vol. 254, pp. 19-26, ISSN:1090-7807 DOI Accesso ONLINE all'editore

Baronti, Lorenzo; Erales, Jenny; Habchi, Johnny; Felli, Isabella C.; Pierattelli, Roberta; Longhi, Sonia (2015). Dynamics of the intrinsically disordered C-terminal domain of the nipah virus nucleoprotein and interaction with the X domain of the phosphoprotein as unveiled by NMR spectroscopy. CHEMBIOCHEM, vol. 16, pp. 268-276, ISSN:1439-4227 DOI Accesso ONLINE all'editore

Andreas, Loren B.; Stanek, Jan; Le Marchand, Tanguy; Bertarello, Andrea; Cala-De Paepe, Diane; Lalli, Daniela; Krejčíková, Magdaléna; Doyen, Camille; Öster, Carl; Knott, Benno; Wegner, Sebastian; Engelke, Frank; Felli, Isabella C.; Pierattelli, Roberta; Dixon, Nicholas E.; Emsley, Lyndon; Herrmann, Torsten; Pintacuda, Guido (2015). Protein residue linking in a single spectrum for magic-angle spinning NMR assignment. JOURNAL OF BIOMOLECULAR NMR, vol. 62, pp. 253-261, ISSN:0925-2738 DOI Accesso ONLINE all'editore

Felli, Isabella C; Pierattelli, Roberta (2015). Spin-state-selective methods in solution- and solid-state biomolecular 13C NMR. PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY, vol. 84-85, pp. 1-13, ISSN:0079-6565 DOI Accesso ONLINE all'editore

Felli, Isabella C; Pierattelli, Roberta (2015). Intrinsically disordered proteins studied by NMR spectroscopy. di Priyanka Joshi, Jenny Erales, David Blocquel, Johnny Habchi, Matilde Beltrandi, Antoine Gruet, Marion Dosnon, Christophe Bignon, Sonia Longhi, Mihaly Varadi, Cesyen Cedeño, Hadas Raveh-Amit, András Dinnyés, Pallab Bhowmick, Mainak Guharoy, Peter Tompa, Michael Kachala, Erica Valentini, Dmitri I. Svergun, A. Keith Dunker, Christopher J. Oldfield, Biao Fu, Michele Vendruscolo, Bernhard Brutscher, Isabella C. Felli, Sergio Gil-Caballero, Tomáš Hošek, Rainer Kümmerle, Alessandro Piai, Roberta Pierattelli, Zsófia Sólyom, Jaka Kragelj, Martin Blackledge, Malene Ringkjøbing Jensen, Dennis Kurzbach, Georg Kontaxis, Nicolas Coudevylle, Robert Konrat, Eduardo O. Calçada, Magdalena Korsak, Tatiana Kozyreva, Vladimir N. Uversky, Springer International Publishing, pp. 1-421, 9783319201641. Accesso ONLINE all'editore

Leonid Breydo;Krishna D. Reddy;Alessandro Piai;Isabella C. Felli;Roberta Pierattelli;Vladimir N. Uversky (2014). The crowd you're in with: Effects of different types of crowding agents on protein aggregation. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, vol. 1844, pp. 346-357, ISSN:1570-9639 DOI

Isabella C Felli;Leonardo Gonnelli;Roberta Pierattelli (2014). In-cell 13C NMR spectroscopy for the study of intrinsically disordered proteins. NATURE PROTOCOLS, vol. 9, pp. 2005-2016, ISSN:1754-2189 DOI

Isabella C. Felli; Roberta Pierattelli (2014). Novel methods based on 13C detection to study intrinsically disordered proteins. JOURNAL OF MAGNETIC RESONANCE, vol. 241, pp. 115-125, ISSN:1090-7807 DOI

M. Varadi;S. Kosol;P. Lebrun;E. Valentini;M. Blackledge;A. K. Dunker;I. C. Felli;J. D. Forman-Kay;R. W. Kriwacki;R. Pierattelli;J. Sussman;D. I. Svergun;V. N. Uversky;M. Vendruscolo;D. Wishart;P. E. Wright;P. Tompa (2014). pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins. NUCLEIC ACIDS RESEARCH, vol. 42, pp. D326-D335, ISSN:0305-1048 DOI Accesso ONLINE all'editore

Piai A; Hošek T; Gonnelli L; Zawadzka-Kazimierczuk A; Koźmiński W; Brutscher B; Bermel W; Pierattelli R; Felli IC. (2014). "CON-CON" assignment strategy for highly flexible intrinsically disordered proteins. JOURNAL OF BIOMOLECULAR NMR, vol. 60, pp. 209-218, ISSN:0925-2738 DOI Accesso ONLINE all'editore

Sergio Gil; Tomas Hosek; Zsofia Solyom; Rainer Kuemmerle; Bernhard Brutscher; Roberta Pierattelli; Isabella C. Felli (2013). NMR Spectroscopic Studies of Intrinsically Disordered Proteins at Near-Physiological Conditions. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 52, pp. 11808-11812, ISSN:1433-7851 DOI

M.J. Knight; I.C. Felli; R. Pierattelli; L. Emsley; G. Pintacuda (2013). Magic Angle Spinning NMR of Paramagnetic Proteins. ACCOUNTS OF CHEMICAL RESEARCH, vol. 46, pp. 2108-2116, ISSN:0001-4842 DOI Accesso ONLINE all'editore

Eduardo O. Calçada; Isabella C. Felli; Tomas Hosek; Roberta Pierattelli (2013). The Heterogeneous Structural Behavior of E7 from HPV16 Revealed by NMR Spectroscopy. CHEMBIOCHEM, vol. 14, pp. 1876-1882, ISSN:1439-4227 DOI

Wolfgang Bermel; Marta Bruix; Isabella C. Felli; Vasantha Kumar M. V.; Roberta Pierattelli; Soraya Serrano (2013). Improving the chemical shift dispersion of multidimensional NMR spectra of intrinsically disordered proteins. JOURNAL OF BIOMOLECULAR NMR, vol. 55, pp. 231-237, ISSN:0925-2738 DOI

Wolfgang Bermel;Isabella C. Felli;Leonardo Gonnelli;Wiktor Kozminski;Alessandro Piai;Roberta Pierattelli;Anna Zawadzka-Kazimierczuk (2013). High-dimensionality 13C direct-detected NMR experiments for the automatic assignment of intrinsically disordered proteins. JOURNAL OF BIOMOLECULAR NMR, vol. 57, pp. 353-361, ISSN:0925-2738 DOI

Lucia Banci;Ivano Bertini;Chiara Cefaro;Simone Ciofi-Baffoni;Karolina Gajda;Isabella C. Felli;Angelo Gallo;Anna Pavelkova;Emmanouela Kallergi;Maria Andreadaki;Nitsa Katrakili;Charalambos Pozidis;Kostas Tokatlidis (2013). An Intrinsically Disordered Domain Has a Dual Function Coupled to Compartment-Dependent Redox Control. JOURNAL OF MOLECULAR BIOLOGY, vol. 425, pp. 594-608, ISSN:0022-2836 DOI

Emeline Barbet-Massin;Andrew J. Pell;Michael J. Knight;Amy L. Webber;Isabella C. Felli;Roberta Pierattelli;Lyndon Emsley;Anne Lesage;Guido Pintacuda (2013). 13C-Detected Through-Bond Correlation Experiments for Protein Resonance Assignment by Ultra-Fast MAS Solid-State NMR. CHEMPHYSCHEM, vol. 14, pp. 331-337, ISSN:1439-4235 DOI

Felli I; Piai A; Pierattelli R (2013). Recent Advances in Solution NMR Studies: 13C Direct Detection for Biomolecular NMR applications. In: Graham Webb. Annual Reports on NMR Spectroscopy, pp. 359-418, Oxford, UK: Academic Press, Elsevier Science, ISBN:9780124080973. DOI

Felli I (2013). BioNMR: an opportunity for biologists. THE FEBS JOURNAL, vol. 280, pp. 627-627, ISSN:1742-4658 DOI Accesso ONLINE all'editore

Felli I (2013). Putting the right spin on it. CHEMPHYSCHEM, vol. 14, pp. 2998-2999, ISSN:1439-7641 DOI

Felli I.C.; Pierattelli R. (2012). 13C direct detection NMR. In: Bertini I.; McGreevy K.S.; Parigi G.. NMR of biomolecules, pp. 433-442, Weinheim: Wiley-VCH, ISBN:978-352732850-5. DOI

W. Bermel; I. Bertini; J. Chill; I.C. Felli; N. Haba; M.V. Kumar; R. Pierattelli (2012). Exclusively Heteronuclear 13C-Detected Amino-Acid-Selective NMR Experiments for the Study of Intrinsically Disordered Proteins (IDPs). CHEMBIOCHEM, vol. 13, pp. 2425-2432, ISSN:1439-4227 DOI

Felli I.C. (2012). Recent progress in NMR spectroscopy: towards the study of intrinsically disordered proteins of increasing size and complexity. THE FEBS JOURNAL, vol. 279, pp. 9-9, ISSN:1742-464X DOI

Popovic M.; Zlatev V.; Hodnik V.; Anderluh G.; Felli I.C.; Pongor S.; Pintar A. (2012). Flexibility of the PDZ-binding motif in the micelle-bound form of Jagged-1 cytoplasmic tail. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, vol. 1818, pp. 1706-1716, ISSN:0005-2736 DOI

Felli I.C.; Pierattelli R.; Tompa P. (2012). Intrinsically disordered proteins. In: Bertini I.; McGreevy K.S.; Parigi G.. NMR of biomolecules, pp. 137-152, Weinheim: Wiley-VCH, ISBN:978-352732850-5. DOI

M. J. Knight; A. J. Pell; I. Bertini; I. C. Felli; L. Gonnelli; R. Pierattelli; T. Herrmann; L. Emsley; G. Pintacuda (2012). Structure and backbone dynamics of a microcrystalline metalloprotein by solid-state NMR. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 109, pp. 11095-11100, ISSN:0027-8424 DOI

A. Mainz;B. Bardiaux;F. Kuppler;G. Multhaup;I. C. Felli;R. Pierattelli;B. Reif (2012). Structural and Mechanistic Implications of Metal Binding in the Small Heat-shock Protein B-crystallin. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 287, pp. 1128-1138, ISSN:0021-9258 DOI

S.Tottey; C.J.Patterson; L.Banci; I.Bertini; I.C.Felli; A.Pavelkova; S.J.Dainty; R.Pernil; K.J.Waldron; A.W.Foster; N.J.Robinson (2012). Cyanobacterial metallochaperone inhibits deleterious side reactions of copper. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 109, pp. 95-100, ISSN:0027-8424 DOI

A.L. Webber; A.J. Pell; E. Barbet-Massin; M.J. Knight; I. Bertini; I.C. Felli; R. Pierattelli; L. Emsley; A. Lesage; G. Pintacuda (2012). Combination of DQ and ZQ Coherences for Sensitive Through-Bond NMR Correlation Experiments in Biosolids under Ultra-Fast MAS. CHEMPHYSCHEM, vol. 13, pp. 2405-2411, ISSN:1439-4235 DOI

M.J. Knight; I.C. Felli; R. Pierattelli; I. Bertini; L. Emsley; T. Herrmann; G. Pintacuda (2012). Rapid Measurement of Pseudocontact Shifts in Metalloproteins by Proton-Detected Solid-State NMR Spectroscopy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 134, pp. 14730-14733, ISSN:0002-7863 DOI Accesso ONLINE all'editore

I.C. Felli; R. Pierattelli (2012). Recent progress in NMR spectroscopy: Toward the study of intrinsically disordered proteins of increasing size and complexity. IUBMB LIFE, vol. 64, pp. 473-481, ISSN:1521-6543 DOI

W. Bermel; I. Bertini; I.C. Felli; L. Gonnelli; W. Koźmiński; A. Piai; R. Pierattelli; J. Stanek (2012). Speeding up sequence specific assignment of IDPs. JOURNAL OF BIOMOLECULAR NMR, vol. 53, pp. 293-301, ISSN:0925-2738 DOI

I.Bertini; I.C.Felli; L.Gonnelli; M.Vasantha Kumar; R.Pierattelli (2011). High-Resolution Characterization of Intrinsic Disorder in Proteins: Expanding the Suite of (13)C-Detected NMR Spectroscopy Experiments to Determine Key Observables. CHEMBIOCHEM, vol. 12, pp. 2347-2352, ISSN:1439-4227 DOI

M.J.Knight; A.L.Webber; A.J.Pell; P.Guerry; E.Barbet-Massin; I.Bertini; I.C.Felli; L.Gonnelli; R.Pierattelli; L.Emsley; A.Lesage; T.Hermann; G.Pintacuda (2011). Fast resonance assignment and fold determination of human superoxide dismutase by high-resolution proton-detected solid state MAS NMR spectroscopy. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 50, pp. 11697-11701, ISSN:1433-7851 DOI Accesso ONLINE all'editore

F.Arnesano; L.Banci; I.Bertini; I.C.Felli; M.Losacco; G.Natile (2011). Probing the interaction of cisplatin with the human copper chaperone Atox1 by solution and in-cell NMR spectroscopy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 133 (45), pp. 18361-18369, ISSN:0002-7863 DOI

I.Bertini; I.C.Felli; L.Gonnelli; M.V.Kumar; R.Pierattelli (2011). 13C Direct-Detection Biomolecular NMR Spectroscopy in Living Cells. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 50, pp. 2339-2341, ISSN:1433-7851 DOI Accesso ONLINE all'editore

I.Bertini; L.Emsley; I.C.Felli; S.Laage; A.Lesage; J.R. Lewandowski; A.Marchetti; R.Pierattelli; G.Pintacuda (2011). High-Resolution and Sensitivity Through-Bond Correlations in Ultra-Fast Magic Angle Spinning (MAS) Solid-State NMR. CHEMICAL SCIENCE, vol. 2, pp. 345-348, ISSN:2041-6520 DOI

P.Turano; D.Lalli; I.C.Felli; E.C.Theil; I.Bertini (2010). NMR reveals a pathway for iron mineral precursors to the central cavity of ferritin. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 107, pp. 545-550, ISSN:1091-6490 DOI

W.Bermel; I.Bertini; I.C.Felli; R.Peruzzini; R.Pierattelli (2010). Exclusively Heteronuclear NMR Experiments to Obtain Structural and Dynamic Information on Proteins. CHEMPHYSCHEM, vol. 11, pp. 689-695, ISSN:1439-4235 DOI

L.Banci;I.Bertini;C.Cefaro;L.Cenacchi;S.Ciofi-Baffoni;I.C.Felli;A.Gallo;L.Gonnelli;E.Luchinat;D.Sideris;K.Tokatlidis (2010). Molecular chaperone function of Mia40 triggers consecutive induced folding steps of the substrate in mitochondrial protein import. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 107 (47), pp. 20190-20195, ISSN:1091-6490 DOI

T.Madl; I.C.Felli; I.Bertini; M.Sattler (2010). Structural analysis of protein interfaces from 13C direct-detected paramagnetic relaxation enhancements. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 132 (21), pp. 7285-7287, ISSN:0002-7863 DOI Accesso ONLINE all'editore

I.C. FELLI; B. BRUTSCHER (2009). Recent advances in solution NMR: fast methods and heteronuclear direct detection. CHEMPHYSCHEM, vol. 10, pp. 1356-1368, ISSN:1439-4235 DOI Accesso ONLINE all'editore

S.Laage; A.Lesage; L.Emsley; I.Bertini; I.C.Felli; R.Pierattelli; G.Pintacuda (2009). Transverse-dephasing optimized homonuclear J-decoupling in solid-state NMR spectroscopy of uniformly 13C-labeled proteins. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 131, pp. 10816-10817, ISSN:0002-7863 DOI

Banci, Lucia; Bertini, Ivano; Calderone, Vito; Della-Malva, Nunzia; Felli, Isabella C.; Neri, Sara; Pavelkova, Anna; Rosato, Antonio (2009). Copper(I)-mediated protein-protein interactions result from suboptimal interaction surfaces. BIOCHEMICAL JOURNAL, vol. 422, pp. 37-42, ISSN:0264-6021 DOI Accesso ONLINE all'editore

W.Bermel; I.Bertini; V.Csizmok; I.C.Felli; R.Pierattelli; P.Tompa (2009). H-start for exclusively heteronuclear NMR spectroscopy: the case of intrinsically disordered proteins. JOURNAL OF MAGNETIC RESONANCE, vol. 198, pp. 275-281, ISSN:1090-7807 DOI

I.C.Felli; R.Pierattelli; S.Glaser; B.Luy (2009). Relaxation-optimised Hartmann-Hahn transfer for carbonyl-carbonyl correlation spectroscopy using a specifically tailored MOCCA-XY16 mixing sequence for protonless 13C direct detection experiments. JOURNAL OF BIOMOLECULAR NMR, vol. 43, pp. 187-196, ISSN:0925-2738 DOI

A. Pavelkova;L. Banci;I. Bertini;V. Calderone;N. D. Malva;I. C. Felli;S. Neri;A. Rosato (2009). Copper(I)-mediated protein-protein interactions result from suboptimal interaction surfaces. THE FEBS JOURNAL, vol. 276, pp. 159-159, ISSN:1742-464X DOI

W.Bermel; I.Bertini; I.C.Felli; R.Pierattelli (2009). Speeding up (13)C direct detection biomolecular NMR spectroscopy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 131, pp. 15339-15345, ISSN:0002-7863 DOI

W. Bermel; I. Bertini; I.C. Felli; R. Kümmerle; R. Pierattelli (2008). Pursuing direct 13C detection for biomolecular NMR in solution. In: Autori Vari. Bruker SpinReport, pp. 26-31, Karlruhe: Bruker BioSpin GmbH.

W.Bermel; I.C.Felli; R.Kummerle; R.Pierattelli (2008). 13C direct-detection biomolecular NMR. CONCEPTS IN MAGNETIC RESONANCE. PART A, BRIDGING EDUCATION AND RESEARCH., vol. 32, pp. 183-200, ISSN:1546-6086 DOI

V.Csizmok; I.C.Felli; P.Tompa; L.Banci; I.Bertini (2008). Structural and Dynamic Characterization of Intrinsically Disordered Human Securin by NMR Spectroscopy.. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 130, pp. 16873-16879, ISSN:0002-7863, J Am Chem Soc: DOI Accesso ONLINE all'editore

I.Bertini; I.C.Felli; C.Luchinat; G.Parigi; R.Pierattelli (2007). Towards a protocol for solution structure determination of copper(II) proteins: the case of Cu(II)Zn(II) superoxide dismutase. CHEMBIOCHEM, vol. 8, pp. 1422-1429, ISSN:1439-4227 DOI

W.Bermel; I.Bertini; I.C.Felli; M.Matzapetakis; R.Pierattelli; E.C.Theil; P.Turano (2007). A method for C(alpha) direct-detection in protonless NMR. JOURNAL OF MAGNETIC RESONANCE, vol. 188, pp. 301-310, ISSN:1090-7807 DOI

L.Banci; I.Bertini; F.Cantini; I.C.Felli; L.Gonnelli; N.Hadjiliadis; R.Pierattelli; A.Rosato; P.Voulgaris (2006). The Atx1-Ccc2 complex is a metal-mediated protein-protein interaction. NATURE CHEMICAL BIOLOGY, vol. 2, pp. 367-368, ISSN:1552-4450 DOI

W.Bermel; I.Bertini; I.C.Felli; Y.M.Lee; C.Luchinat; R.Pierattelli (2006). Protonless NMR experiments for sequence-specific assignment of backbone nuclei in unfolded proteins. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 128, pp. 3918-3919, ISSN:0002-7863 DOI

W.Bermel; I.Bertini; I.C.Felli; M.Piccioli; R.Pierattelli (2006). 13C detected protonless NMR spectroscopy of proteins in solution. PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY, vol. 48, pp. 25-45, ISSN:0079-6565 DOI

W.Bermel; I.Bertini; I.C.Felli; R.Kuemmerle; R.Pierattelli (2006). Novel 13C direct detection experiments, including extension to the third dimension, to perform the complete assignment of proteins. JOURNAL OF MAGNETIC RESONANCE, vol. 178, pp. 56-64, ISSN:1090-7807, Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445: DOI

I.Bertini; I.C.Felli; L.Gonnelli; R.Pierattelli; Z.Spyranti; G.A.Spyroulias (2006). Mapping protein-protein interaction by 13C´-detected heteronuclear NMR spectroscopy. JOURNAL OF BIOMOLECULAR NMR, vol. 36, pp. 111-122, ISSN:0925-2738 DOI

E. Babini; I.C. Felli; M. Lelli; C. Luchinat; R. Pierattelli (2005). Backbone and side-chains 1H, 13C and 15N NMR assignment of human beta-parvalbumin. JOURNAL OF BIOMOLECULAR NMR, vol. 33, pp. 137-137, ISSN:0925-2738, Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254: DOI

L. Banci; I. Bertini; I.C.Felli; R. Pierattelli; Z. Spyranti; G. Spyroulias (2005). Protonless NMR for the Study of Protein-Protein Interactions. In: 46th ENC, Providence, USA, 10-15 Aprile 2005, ENC Conference, pp. 0-0.

W.Bermel; I.Bertini; L.Duma; I.C.Felli; L.Emsley; R.Pierattelli; P.R.Vasos (2005). Complete assignment of heteronuclear protein resonances by protonless NMR spectroscopy. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 44, pp. 3089-3092, ISSN:1433-7851

W.Bermel; I.Bertini; I.C.Felli; R.Pierattelli; P.R.Vasos (2005). A selective experiment for the sequential protein backbone assignment from 3D heteronuclear spectra. JOURNAL OF MAGNETIC RESONANCE, vol. 172, pp. 324-328, ISSN:1090-7807, Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445:

L.Banci; I.Bertini; I.C.Felli; J.Sarrou (2005). Backbone-only restraints for fast determination of the protein fold: the role of paramagnetism-based restraints. Cytochrome b562 as an example. JOURNAL OF MAGNETIC RESONANCE, vol. 172, pp. 191-200, ISSN:1090-7807, Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445: DOI

I.Bertini; I.C.Felli; R.Kuemmerle; D.Moskau; R.Pierattelli (2004). 13C-13C NOESY: an attractive alternative for studying large macromolecules. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 126, pp. 464-465, ISSN:0002-7863 DOI

I.Bertini; I.C.Felli; R.Kuemmerle; C.Luchinat; R.Pierattelli (2004). (13)C-(13)C NOESY: a constructive use of (13)C-(13)C spin-diffusion. JOURNAL OF BIOMOLECULAR NMR, vol. 30, pp. 245-251, ISSN:0925-2738 DOI

I.Bertini; L.Duma; I.C.Felli; M.Fey; C.Luchinat; R.Pierattelli; P.R.Vasos (2004). A heteronuclear direct-detection NMR spectroscopy experiment for protein-backbone assignment. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 43, pp. 2257-2259, ISSN:1433-7851 DOI

E.Babini; I.Bertini; F.Capozzi; I.C.Felli; M.Lelli; C.Luchinat (2004). Direct carbon detection in paramagnetic metalloproteins to further exploit pseudocontact shift restraints. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 126, pp. 10496-10497, ISSN:0002-7863 DOI

W.BERMEL; I.BERTINI; I.C.FELLI; R.KUEMMERLE; R.PIERATTELLI (2003). 13C direct detection experiments on the paramagnetic oxidized monomeric copper, zinc superoxide dismutase. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 125, pp. 16423-16429, ISSN:0002-7863

BANCI L; BERTINI I; FELLI IC; KRIPPAHL L; KUBICEK K; MOURA J.J; ROSATO A; (2003). A further investigation of the cytochrome b5 – cytochrome c complex. JBIC, vol. 8, pp. 777-786, ISSN:0949-8257 DOI

L. BANCI; F. ARNESANO; I. BERTINI; I. FELLI; C. LUCHINAT; A. THOMPSETT (2003). A strategy for the NMR characterization of type II copper(II) proteins: the case of copper trafficking protein CopC from Pseudomonas syringae.. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 125, pp. 7200-7208, ISSN:0002-7863 DOI

L. Banci; I. C. Felli; R. Kummerle (2002). Direct detection of hydrogen bonds in monomeric superoxide dismutase: Biological implications. BIOCHEMISTRY, vol. 41, pp. 2913-2920, ISSN:0006-2960 DOI

M. Piccioli;T. Lehmann;C. Luchinat;I. Bertini;I. Felli;A. Rosato (2001). [Fe4S4](2/3+) HiPIP proteins: from structure in solution to redox shifts. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 86, pp. 507-507, ISSN:0162-0134

L.BANCI; I.BERTINI; I.C.FELLI; P.HAJIEVA; M.S.VIEZZOLI (2001). Side chain mobility as monitored by CH-CH cross correlation: the example of cytochrome b5.. JOURNAL OF BIOMOLECULAR NMR, vol. 20, pp. 1-10, ISSN:0925-2738

Y. M. Lee;F. Arnesano;L. Banci;R. Barbieri;I. Bertini;I. Felli;C. Luchinat;M. Piccioli;J. Sarrou;A. Rosato (2001). Self orientation of paramagnetic molecules in high magnetic fields for structure determination. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 86, pp. 504-504, ISSN:0162-0134

F. Arnesano;L. Banci;I. Bertini;I. Felli;P. Hajieva;D. Koulougliotis;C. Luchinat;A. Rosato;G. Spyroulias;P. Turano;M. S. Viezzoli (2001). Cytochrome b5. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 86, pp. 495-495, ISSN:0162-0134

I. Bertini; I. C. Felli (2001). NMR of paramagnetic proteins: structure, function and stability. In: I. Bertini, I.C. Felli. Dynamics, structure and function of biological macromolecules, pp. 117-131, Dordrecht: Academic Publishers.

BERTINI I; FELLI I.C.; LUCHINAT C (2000). Lanthanide induced residual dipolar couplings for the conformational investigation of peripheral 15NH2 moieties. JOURNAL OF BIOMOLECULAR NMR, vol. 18, pp. 347-355, ISSN:0925-2738 DOI

JUNKER J; REIF B; STEINHAGEN H; JUNKER B; I. FELLI; REGGELIN M; GRIESINGER C (2000). Structure determination of a key intermediate of the enantioselective Pd complex catalyzed allylic substitution reaction. CHEMISTRY-A EUROPEAN JOURNAL, vol. 6, pp. 3281-3286, ISSN:0947-6539

CARLOMAGNO T; I. FELLI; CZECH M; FISHER R; SPRINZL M; GRIESINGER C (1999). Transferred cross correlated relaxation: application to the determination of sugar pucker in aminoacylated tRNA-mimetic weakly bound to EF-Tu. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 121, pp. 1945-1948, ISSN:0002-7863, American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671:

I. FELLI; RICHTER C; GRIESINGER C; SCHWALBE H (1999). Determination of RNA sugar pucker mode from cross correlated relaxation in solution NMR spectroscopy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 121, pp. 1956-1957, ISSN:0002-7863, American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671:

F.ARNESANO; L.BANCI; I.BERTINI; I.C. FELLI; D.KOULOUGLIOTIS (1999). Solution structure of the B form of oxidized rat microsomal cytochrome b5 and backbone dynamics via 15N rotating frame NMR relaxation measurements: biological implications. EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 260, pp. 347-354, ISSN:0014-2956

RICHTER C; GRIESINGER C; I. FELLI; COLE P.T; VARANI G; SCHWALBE H (1999). Determination of sugar conformation in large RNA oligonucleotides from analysis of dipole-dipole cross correlated relaxation by solution NMR spectroscopy. JOURNAL OF BIOMOLECULAR NMR, vol. 15, pp. 241-250, ISSN:0925-2738, Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254:

L. Banci; I. C. Felli; D. Koulougliotis (1998). Identification of slow motions in the reduced recombinant high-potential iron sulfur protein I (HiPIP I) from Ectothiorhodospira halophila via N-15 rotating-frame NMR relaxation measurements. JOURNAL OF BIOMOLECULAR NMR, vol. 12, pp. 307-318, ISSN:0925-2738

BERTINI I; FELLI I.C.; LUCHINAT C (1998). High magnetic field consequences on the NMR hyperfine shifts in solution. JOURNAL OF MAGNETIC RESONANCE, vol. 134, pp. 360-364, ISSN:0022-2364

L.BANCI; I.BERTINI; C.CAVAZZA; I.C.FELLI; D.KOULOUGLIOTIS (1998). Probing the backbone dynamics of oxidized and reduced rat microsomal cytochrome b5 via 15N rotating frame NMR relaxation measurements: biological implications. BIOCHEMISTRY, vol. 37, pp. 12320-12330, ISSN:0006-2960

F.ARNESANO; L.BANCI; I.BERTINI; I.C.FELLI (1998). The solution structure of oxidized rat microsomal cytochrome b5. BIOCHEMISTRY, vol. 37, pp. 173-184, ISSN:0006-2960

I. FELLI; DESVAUX H; BODENHAUSEN G (1998). Local Mobility of 15N labeled biomolecules characterized through cross-correlation rates: applications to paramagnetic proteins. JOURNAL OF BIOMOLECULAR NMR, vol. 12, pp. 509-520, ISSN:0925-2738, Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254:

BERTINI I; DONAIRE A; I. FELLI; LUCHINAT C; ROSATO A (1997). 1H and 13C NMR studies of an oxidized HiPIP. INORGANIC CHEMISTRY, vol. 36, pp. 4798-4803, ISSN:0020-1669, American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671:

BERTINI I; BORSARI M; BOSI M; ELTIS L.D; I.C. FELLI; LUCHINAT C; PICCIOLI M (1996). The influence of a surface charge on the electronic and steric structure of a high potential iron-sulfur protein. JBIC, vol. 1, pp. 257-263, ISSN:0949-8257

I. Bertini; I. C. Felli; C. Luchinat; A. Rosato (1996). A complete relaxation matrix refinement of the solution structure of a paramagnetic metalloprotein: reduced HiPIP I from Ectothiorhodospira halophila.. PROTEINS, vol. 24, pp. 158-164, ISSN:0887-3585

I. Bertini; M. M. Couture; A. Donaire; L. D. Eltis; I. C. Felli; C. Luchinat; M. Piccioli; A. Rosato (1996). The solution structure refinement of the paramagnetic reduced high-potential iron-sulfur protein I from Ectothiorhodospira halophila by using stable isotope labeling and nuclear relaxation.. EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 241, pp. 440-452, ISSN:0014-2956

BERTINI I; DONAIRE A; I.C. FELLI; LUCHINAT C; ROSATO A (1996). From NOESY cross peaks to structural constraints in a paramagnetic metalloprotein. MAGNETIC RESONANCE IN CHEMISTRY, vol. 34, pp. 948-950, ISSN:0749-1581

JEANNERAT D; BLUE A; BOULAT B; CUTTING B; DESVAUX H; I. FELLI; FU R; HUTH J; MEERSMANN T; MURALI N; MUTZENHARDT P; PALMER J.A; PELUPESSY P; PENG C; SCHWAGER M; SMITH S; VINCENT S; ZWAHLEN C. AND BODENHAUSEN G (1996). Two years of NMR developments at the National High Magnetic Field Laboratory in Tallahassee, USA. CHIMIA, vol. 50, pp. 633-638, ISSN:0009-4293, Swiss Chemical Society:Barenplatz 2, CH 3011 Bern Switzerland:011 41 31 3104090, EMAIL: info@swiss-chem-soc.ch, markus.straub@swiss-chem-soc.ch, INTERNET: http://www.swiss-chem-soc.ch, Fax: 011 41 31 3121678:

BERTINI I; CAPOZZI F; ELTIS L.D; I.C. FELLI; LUCHINAT C; PICCIOLI M (1995). Sequence-specific assignement of ligand cysteine protons of oxidized, recombinant HiPIP I from Ectothiorhodospira halophila. INORGANIC CHEMISTRY, vol. 34, pp. 2516-2523, ISSN:0020-1669

BERTINI I; ELTIS L.D; I.C. FELLI; KASTRAU D.H.W; LUCHINAT C; PICCIOLI M (1995). The solution structure of oxidized HiPIP I from Ectothiorhodospira halophila. Can NMR spectroscopy be used to probe rearrangements associated with electron transfer processes?. CHEMISTRY-A EUROPEAN JOURNAL, vol. 1, pp. 598-607, ISSN:0947-6539

DIKANOV S.A; TYRYSHKIN M.A; I. FELLI; REIJERSE E.J; HUETTERMANN J (1995). C-band ESEEM of strongly coupled peptide nytrogens in reduced two-iron ferredoxin. JOURNAL OF MAGNETIC RESONANCE SERIES B, vol. 108, pp. 99-102, ISSN:1064-1866

IWAGAMI S.G; CREAGH A.L; HAYNES C.A; BORSARI M; I.C. FELLI; PICCIOLI M; ELTIS L.D (1995). The role of a conserved tyrosine residue in high-potential iron-sulfur proteins. PROTEIN SCIENCE, vol. 4, pp. 2562-2572, ISSN:0961-8368

BERTINI I; I.C. FELLI (1995). The structure determination of proteins in solution by NMR. Now it is possible also for paramagnetic proteins. LA CHIMICA E L'INDUSTRIA, vol. 9, pp. 639-648, ISSN:0009-4315

I. FELLI;L. BANCI;I. BERTINI;L. D. EITIS;D. H. W.;C. LUCHINAT;M. PICCIOLI;R. PIERATTELLI;M. SMITH (1995). Solution Structure of the Recombinant Iron-sulfur Protein Iso-i (hipip-i) From E-halophila, In Both Oxidation-states. JOURNAL OF CELLULAR BIOCHEMISTRY, pp. 45-45, ISSN:0730-2312

I. BERTINI; I. C. FELLI; D. H. W. KASTRAU; C. LUCHINAT; M. PICCIOLI; M. S. VIEZZOLI (1994). Sequence-Specific Assignment Of The H-1 And N-15 Nuclear-Magnetic-Resonance Spectra Of The Reduced Recombinant High-Potential Iron-Sulfur Protein-I From Ectothiorhodospira-Halophila. EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 225, pp. 703-714, ISSN:0014-2956

DIKANOV S; I.C. FELLI; VIEZZOLI M.S; SPOYALOV A; HUETTERMANN J (1994). X-band ESEEM spectroscopy of 15N substituted native and inhibitor bound superoxide dismutase. Hyperfine couplings with remote nitrogen of histidine ligands. FEBS LETTERS, vol. 345, pp. 55-60, ISSN:0014-5793

L. Banci; I. Bertini; L. D. Eltis; I. C. Felli; D. H. Kastrau; C. Luchinat; M. Piccioli; R. Pierattelli; M. Smith (1994). The three-dimensional structure in solution of the paramagnetic high-potential iron-sulfur protein I from Ectothiorhodospira halophila through nuclear magnetic resonance.. EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 225, pp. 715-725, ISSN:0014-2956

Isabella Caterina FELLI

Insegnamenti relativi all'Anno Accademico

- - -

Isabella Caterina FELLI

Biography Isabella C. Felli graduated with a degree in Chemistry in 1994 and obtained the PhD in Chemistry in 1998 at the University of Florence (Italy) under the supervision of Prof. Ivano Bertini. She joined the group of Prof. Geoffrey Bodenhausen as visiting student at the NHMFL in Tallahassee. She received an Alexander von Humbold fellowship for a post-doctoral position in Frankfurt with Prof. Christian Griesinger. She also received several other grants (including Marie Curie, DAAD, EMBO) as well as awards during this period (prize by Federchimica for her undergraduate thesis, prize by the Italian Chemical Society for her PhD work). She then returned to Florence in the group of Prof. Ivano Bertini. Since 2005 she is associate professor (CHIM/03) at the University of Florence. She is a member of the Supervisory Board of the Doctorate in Chemistry (Faculty of Science) and of the International Doctorate in Structural Biology (Faculty of Science). She has been involved since 2006, as a local operator, in several EC supported projects to provide access to NMR research infrastructures (EUNMR, EASTNMR, BioNMR). She is coordinating an EC Marie Curie Initial Training Network (ITN) "High resolution tools to understand the functional role of protein intrinsic disorder" (IDPbyNMR, 8 partners, 3.4 M, starting date 001/11/2012, duration: 4 years). She has been invited to many international meetings as a speaker (some recent examples include the ICMRBS 2012, ISMAR 2013, EUROMAR 2013). Her main research interest consists in the application and development of NMR methods to study metalloproteins, macromolecules of biological interest and their interactions with metal ions. She is author of 80 publications in international journals.

Isabella Caterina FELLI

Curriculum Isabella Caterina Felli
Born in Charlottesville, Virginia, USA

from 01/11/2005
Associate Professor (CHIM/03), University of Florence, Department of Chemistry "Ugo Schiff"

from 05/2001 to 10/2005
Professor of the Faculty of Mathematics, Physics and Natural Sciences of the Univerity of Florence.
Responsible of the course on Food Chemistry (CHIM/03, 6 CFU) of "Corso di Laurea in Chimica Applicata (AA 2001/2002 Corso di Diploma Universitario in Chimica)".
Coordination and support of teaching activities (Education Manager) within "Corso di Laurea in Chimica Applicata (AA 2001/2002 Corso di Diploma Universitario in Chimica)".

from 03/1999 to 04/2001
Research grant, Department of Chemistry, University of Florence.
"NMR studies of paramagnetic metalloproteins" (scientific supervisor Prof. Ivano Bertini).

from 04/1998 to 11/1998
Alexander von Humboldt Post-doc, University of Frankfurt, Germany.
"Development of new NMR methods" (scientific supervisor Prof. Christian Griesinger).

from 11/1997 to 03/1998 and from 11/1998 to 02/1999
Research grant of the Departmentof Chemistry, University of Florence.
"NMR of paramagnetic metalloproteins" (scientific supervisor Prof. Ivano Bertini).

from 04/1996 to 09/1996
Research grant of the National High Magnetic Field Laboratory (NHMFL), Tallahassee, Florida, USA.
"Development of new NMR methods to determine the dynamic properties of paramagnetic metalloproteins in solution through the study of cross-correlated relaxation rates" (scientific supervisor Prof. Geoffrey Bodenhausen).

from 11/1994 to 10/1997
Doctorate in Chemical Sciences (X cycle)
"From electron and nuclear spins to the structure and dynamics of paramagnetic metalloproteins involved in electron transfer" (scientific supervisor Prof. I. Bertini).

from 03/1993 to 05/1993
Research grant by CRUI ("Progetto Vigoni"), Universität Saarlandes, Homburg, Germany.
"Application of electron magnetic resonance spectroscopy (continous wave and pulsed EPR ed ESEEM) to the study of paramagnetic metalloproteins" (scientific supervisor Prof. Jurgen Huttermann).

from 05/1994 to 10/1994
Research grant by Bruker Spectrospin Italiana S.r.l. - Department of Chemistry, University of Florence.
"Development of instrumental techniques for the study of paramagnetic metalloproteins" (scientific supervisor Prof. Ivano Bertini).

On 04/1994 - Tesi di Laurea
"From the ESEEM study of superoxide dismutase to the NMR solution structure of a high potential iron sulfur proteins" (scientific supervisor Prof. Ivano Bertini).

Research interests
Development of new methods based on NMR spectroscopy for the study of metalloproteins, of macromolecules of biological interest and of their interactions with metal ions.
The main results include: 1) the determination of the first solution structure of a paramagnetic metalloprotein through NMR (undergraduate thesis), followed by several other examples and by the development of the relative methodology, 2) development of new NMR methods for the determination of local mobility, 3) development of new NMR methods based on 13C direct detection for the study of proteins, 4) development of new solid state NMR methods, 5) development of new NMR methods for the study of intrinsically disordered proteins (IDP).
The scientific results, described in 80 publications (plus two just submitted forpublication), have been presented at many international meetings (32 oral presentations, 41 poster presentations).

Teaching activity (CHIM/03), Faculty of Mathematics, Physical and Natural Sciences, University of Florence

Academic Year 2011/2012 - today
"Corso di Laurea Magistrale SCIENZE CHIMICHE"
NMR IN STRUCTURAL BIOLOGY (6 CFU)
Academic Year 2010/2011
"Corso di Laurea Magistrale SCIENZE CHIMICHE"
LABORATORY of INORGANIC STRUCTURAL GENOMICS (6 CFU)
Academic Year 2009/2010 - oggi
"Corso di Laurea Magistrale SCIENZE CHIMICHE"
SPECTROSCOPIC METHODS IN INOGRANIC CHEMISRTY (6 CFU)
Academic Year 2009/2010 - AA 2010/2011
"Corso di Laurea CHIMICA"
NM SPETTROSCOPY (6 CFU)
Academic Year 2008/2009
"Corso di Laurea Specialistica CHIMICA"
SPECTROSCOPIC METHODS AND MAGNETIC RESONANCE, Module II (3 CFU)
Academic Year 2006/2007 AA 2010/2011
"Corso di Laurea CHIMICA"
PHYSICAL METHODS IN INOGRANIC CHEMISRTY (6 CFU)
Academic Year 2005/2006 AA 2009/2010
"Corso di Laurea Specialistica CHIMICA DELLE MOLECOLE BIOLOGICHE"
INORGANIC STRUCTURAL GENOMICS (6 CFU)
Academic Year 2001/2002 AA 2007/2008
"Corso di Laurea CHIMICA APPLICATA"
FOOD CHEMISTRY(6 CFU)

Courses for the International Doctorate in Structural Biology, University of Florence
from 2002 to 2009 one course per year entitled "Improving the NMR culture"

Peer-reviewed scientific projects supervised (title of the project, duration in months, role covered):

IDPbyNMR, Marie Curie Initial Training Network, EC contract number 264257, FP7, 48 Coordinator
BioNMR, Combination of CP and CSA, EC contract number 261863, FP7, 48 Local Operator
EASTNMR, Combination of CP and CSA, EC contract number 228461, FP7, 48 Local Operator
EUNMR, Integrated Infrastructure Initiative I3, contract number RII3-026145, FP7, 48 Local Operator

Partecipation to editorial initiatives (type, title, period):

Journal - ChemPhysChem - editor of one issue dedicated to NMR - ongoing 08/2012 09/2013
Book series - Advances in Experimental Medicine and Biology series - editor of one volume - ongoing 07/2012

Competitive research grants awarded (type, institution, period):

Alexander von Humboldt fellowship, University of Frankfurt, Germany 04/1998 11/1998
National High Magnetic Field Laboratory (NHMFL) fellowship, FL, USA 04/1996 09/1996
CRUI fellowship (Progetto Vigoni), Universität Saarlandes, Homburg, Germania 03/1993 05/1993

Partecipazione ad accademie aventi prestigio nel settore (accademia, periodo):

AMPERE Group, Member of the AMPERE Committee since 07/2010
Alexander von Humboldt Foundation, Member since 04/1998
Marie Curie Fellows Association, Member since 07/1998

Awards for her scientific activity:

1999 Award for her PhD from the Italian Chemical Society, Division of Inorganic Chemistry for PhD Thesis (X cycle)
1995 National Award by Federchimica "Federchimica - Per un futuro intelligente" for her "Tesi di Laurea"
1986 Award trip to Strasburg " 50 young students at the European Parliament"

1998 competitive fellowships awarded:
Alexander von Humboldt fellowship
Marie Curie Research Training Grant ERB4001GT974957 TMR program
EMBO (European Molecular Biology Organization) Short term fellowship
DAAD (Deutscher Akademischer Austauschdienst) Research scholarship

Other titles
Presentations at international conferences and advanced training courses:
3 invited presentations in 2013 (one of them the at the plenary level)
34 oral presentations
41 poster presentations.

Organization of international scientific meetigns:
12 as organizer, 3 as part of the organizing committee.

Reviewer for the following international scientific journals:
Journal of the American Chemical Society, Journal of Biomolecular NMR, PLoS ONE

Supervisor of 4 students for their PhD (1 concluded, 3 ongoing).
Supervisor of 4 "Tesi di Laurea Specialistica in Chimica", of 15 "Tesi di Laurea Triennale in Chimica e Chimica Applicata", and of 5 "Stage di Diploma Universitario in Chimica".
Member of the Board of Teachers of the Doctorate in Chemistry.
Member of the Board of Teachers of the International Doctorate in Structural Biology.

Involved in FIRB and PRIN projects coordinated by Prof. I. Bertini or by Prof. Banci (PRIN09 "Biologia strutturale meccanicistica: avanzamenti metodologici e biologici" - 2009FAKHZT, PRIN 2007 "Gli ioni metallici nelle interazioni proteina-proteina" - 2007M5MWM9, PRIN-COFIN 2005 "Genomica strutturale di metalloproteine e delle loro interazioni funzionali" 2005039878, COFIN 2003 "Il ruolo degli ioni metallici nei processi metabolici" 2003035772_001, FIRB PROTEOMICA "Rete Nazionale per lo studio della Proteomica Umana (Italian Human ProteomeNet)" MIUR-RBRN07BMCT, MIUR-FIRB (Fondo per gli Investimenti della Ricerca di Base) "Piattaforme NMR per lo studio dell'interazione proteine-leganti di interesse farmacologico" - MIUR-RBLA032ZM7).

Isabella Caterina FELLI

Interest NMR, proteins, windsurf

Isabella Caterina FELLI

Isabella Caterina FELLI

Isabella Caterina FELLI

Isabella Caterina FELLI

Isabella Caterina FELLI

Isabella Caterina FELLI

Isabella Caterina FELLI

Insegnamenti relativi all'Anno Accademico 2023-2024 2022-2023 2021-2022 2020-2021 2019-2020 2018-2019 2017-2018 2016-2017 2015-2016 2014-2015 2013-2014 2012-2013 2011-2012 2010-2011 2009-2010 2008-2009 2007-2008

Isabella Caterina FELLI

Isabella Caterina FELLI

Isabella Caterina FELLI

Insegnamenti relativi all'Anno Accademico