Dettori, I ; Gaviano, L ; Melani, A ; Lucarini, L ; Durante, M ; Masini, E ; Pedata, F (2018). A Selective Histamine H4 Receptor Antagonist, JNJ7777120, Is Protective in a Rat Model of Transient Cerebral Ischemia. FRONTIERS IN PHARMACOLOGY, pp. 1-11, ISSN:1663-9812

  Lana, D; Ugolini, F; Melani, A; Nosi, D; Pedata, F; Giovannini, Mg (2017). The neuron-astrocyte-microglia triad in CA3 after chronic cerebral hypoperfusion in the rat: Protective effect of dipyridamole. EXPERIMENTAL GERONTOLOGY, pp. 46-62, ISSN:0531-5565 DOI  

  Pedata, Felicita; Dettori, Ilaria; Fusco, Irene; Coppi, Elisabetta; Pugliese, Anna M.; Melani, Alessia (2017). Adenosine and Oxygen/Glucose Deprivation in the Brain. In: Pedata, Felicita*. Adenosine Receptors in Neurodegenerative Diseases, pp. 151-173 Elsevier Inc., ISBN:9780128037454. DOI   Accesso ONLINE all'editore

  Pedata, Felicita; Dettori, Ilaria; Coppi, Elisabetta; Melani, Alessia; Fusco, Irene; Corradetti, Renato; Pugliese, Anna Maria (2016). Purinergic signalling in brain ischemia. NEUROPHARMACOLOGY, pp. 1-26, ISSN:0028-3908 DOI  

  Dettori, I.; Melani, A.; Cellai, L.; Pedata, F. (2015). Time-course of the protective effect of selective adenosine A2A receptor agonists and antagonists after brain focal ischemia in the rat. In: XVI Meeting Italian Society for Neuroscience, Cagliari, October 8-11, 2015, d, pp. 324-324.

  Dettori, I.; Melani, A.; Cellai, L.; Pedata, F. (2015). Selective adenosine A2A receptor agonists and antagonists protect at different times after brain focal ischemia in the rat. In: 37° Congresso Nazionale della Società Italiana di Farmacologia, I nuovi orizzonti della ricerca farmacologica: tra etica e scienza, Napoli, 27-30 ottobre 2015, d, pp. 0-0.

  Melani A; Dettori I; Corti F; Cellai L; Pedata F. (2015). Time-course of protection by the selective A2A receptor antagonist SCH58261 after transient focal cerebral ischemia.. NEUROLOGICAL SCIENCES, vol. 36, pp. 1441-1448, ISSN:1590-1874 DOI   Accesso ONLINE all'editore

  Cellai, L; Melani, A; Dettori, I; Pugliese, AM; Pedata, F (2015). Effect of chronic administration of selective adenosine A2A receptor agonists and antagonists on cerebral injury evaluated up to seven days after focal ischemia in the rat. In: 6th Joint German-Italian Purine Club Meeting, International conference on purinergic signalling, Hamburg, July, 23-25 2015, d, pp. 70-70.

  Coppi, Elisabetta; Cellai, Lucrezia; Maraula, Giovanna; Dettori, Ilaria; Melani, Alessia; Pugliese, Anna Maria; Pedata, Felicita (2015). Role of adenosine in oligodendrocyte precursor maturation. FRONTIERS IN CELLULAR NEUROSCIENCE, vol. 9, pp. 155-162, ISSN:1662-5102 DOI   Accesso ONLINE all'editore

  Maraula G;Lana D;Coppi E;Gentile F;Mello T;Melani A;Galli A;Giovannini MG;Pedata F;Pugliese AM (2014). The Selective Antagonism of P2X7 and P2Y1 Receptors Prevents Synaptic Failure and Affects Cell Proliferation Induced by Oxygen and Glucose Deprivation in Rat Dentate Gyrus.. PLOS ONE, vol. 9(12): e115273, pp. 1-23, ISSN:1932-6203 DOI  

  Lana, Daniele; Melani, Alessia; Pugliese, Anna Maria; Cipriani, Sara; Nosi, Daniele; Pedata, Felicita; Giovannini, Maria Grazia (2014). The neuron-astrocyte-microglia triad in a rat model of chronic cerebral hypoperfusion: Protective effect of dipyridamole. FRONTIERS IN AGING NEUROSCIENCE, vol. 6, pp. 1-17, ISSN:1663-4365 DOI   Accesso ONLINE all'editore

  Pedata F;Pugliese AM;Coppi E;Dettori I;Maraula G;Cellai L;Melani A (2014). Adenosine A2A Receptors Modulate Acute Injury and Neuroinflammation in Brain Ischemia.. MEDIATORS OF INFLAMMATION, vol. 2014, pp. 1-16, ISSN:0962-9351 DOI  

  Pedata, F; Melani, A; Cellai, L; Dettori, I; Pugliese, AM (2014). Role of adenosine A2A receptors in cerebral ischemia. PURINERGIC SIGNALLING, vol. 10, pp. 667-667, ISSN:1573-9538

  Alessia Melani;Anna Maria Pugliese;Felicita Pedata (2014). Adenosine Receptors in Cerebral Ischemia. In: Alessia Melani, Anna Maria Pugliese, Felicita Pedata. International Review of Neurobiology, pp. 309-348 Mori, A. DOI  

  Ferrè, S; Guitart, X; Rea, W; Orrù, M; Cellai, L; Melani, A; Dettori, I; Lluis, C; Cortés, A; Casadò, V; Pedata, F (2014). Adenosine as a biomarker of Huntington Disease. In: Purines 2014 Nucleotides, Nucleosides and Nucleobases, International conference on signalling, drugs and targets, Bonn, July 23-27 2014, d, pp. 113-114.

  Corti, Francesca; Cellai, Lucrezia; Melani, Alessia; Donati, Chiara; Bruni, Paola; Pedata, Felicita (2013). Adenosine is present in rat brain synaptic vesicles.. NEUROREPORT, vol. 24, pp. 982-987, ISSN:0959-4965 DOI  

  F. Pedata; A.M. Pugliese; F. Corti; A. Melani. (2012). Adenosine and Stroke. In: S. Masino, Boison D. Adenosine: a Key Link between Metabolism and CNS Activity, pp. 1-37, New York: Susan Masino and Detlev Boison EDs, Springer, ISBN:9781461439035. DOI  

  Mazzon E;Esposito E;Impellizzeri D;DI Paola R;Melani A;Bramanti P;Pedata F;Cuzzocrea S (2011). CGS 21680, an agonist of the adenosine (A2A) receptor, reduces progression of murine type II collagen-induced arthritis.. THE JOURNAL OF RHEUMATOLOGY, vol. 38, pp. 2119-2129, ISSN:0315-162X DOI  

  Paterniti I;Melani A;Cipriani S;Corti F;Mello T;Mazzon E;Esposito E;Bramanti P;Cuzzocrea S;Pedata F (2011). Selective adenosine A2A receptor agonists and antagonists protect against spinal cord injury through peripheral and central effects.. JOURNAL OF NEUROINFLAMMATION, vol. 8, pp. 31-44, ISSN:1742-2094 DOI  

  Impellizzeri D;Di Paola R;Esposito E;Mazzon E;Paterniti I;Melani A;Bramanti P;Pedata F;Cuzzocrea S (2011). CGS 21680, an agonist of the adenosine (A2A) receptor, decreases acute lung inflammation.. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 668, pp. 305-316, ISSN:0014-2999 DOI  

  R.Di Paola; A.Melani; E.Esposito; E.Mazzon; I.Paterniti; P.Bramanti; F.Pedata; S.Cuzzocrea (2010). Adenosine A2A receptor-selective stimulation reduces signaling pathways involved in the development of intestine ischemia and reperfusion injury. SHOCK, vol. 33, pp. 541-551, ISSN:1073-2322 DOI  

  Melani A; Cipriani S; Vannucchi MG; Nosi D; Donati C; Bruni P; Giovannini MG; Pedata F (2010). Selective adenosine A(2A) receptor antagonism reduces JNK MAPK activation in oligodendrocytes after cerebral ischaemia. PURINERGIC SIGNALLING, vol. 6, pp. 97-97, ISSN:1573-9538

  F. PEDATA; A. MELANI; F. CORTI; S. CIPRIANI; M.G. GIOVANNINI; G. PEPEU (2010). Selective adenosine A2A receptor antagonism reduces JNK activation in oligodendrocytes after cerebral ischemia.. In: 40th Annual Meeting of the Society for Neuroscience, San Diego, CA (USA), Society for neuroscience, pp. 153.8-153.8.

  Pedata F.; Melani A.; Cipriani S.; Pugliese A.M.; Traini C.; Corti F.; Giovannini MG. (2010). Adenosine A2A antagonists are protective in in vivo and in vitro models of brain ischemia.. PURINERGIC SIGNALLING, vol. 6 (Suppl. 1), pp. S20-S21, ISSN:1573-9538, SPRINGER: DOI  

  A.Melani; S.Cipriani; F.Corti; F.Pedata (2010). Effect of intravenous administration of dipyridamole in a rat model of chronic cerebral ischemia. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 1207, pp. 89-96, ISSN:0077-8923 DOI  

  T.Genovese; A.Melani; E.Esposito; I.Paterniti; E.Mazzon; R.Di Paola; P.Bramanti; J.Linden; F.Pedata; S.Cuzzocrea (2010). Selective adenosine A2A receptor agonists reduce the apoptosis in an experimental model of spinal cord trauma. JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS, vol. 24, pp. 73-86, ISSN:0393-974X

  Pedata F.; Melani A.; Pugliese A.M.; Cipriani S. ; Giovannini M.G. (2009). Adenosine A2A antagonists are protective in in vivo and in vitro models of brain ischemia.. FRONTIERS IN NEUROSCIENCE, vol. Conference Abstract: 3rd Mediterranean Conference of Neuroscience, pp. 1-1, ISSN:1662-453X DOI   Accesso ONLINE all'editore

  A.Melani; S.Cipriani; MG Vannucchi; D Nosi; C Donati; P Bruni; MG Giovannini; F Pedata (2009). Selective adenosine A2A receptor antagonism reduces JNK activation in oligodendrocytes after cerebral ischemia. BRAIN, vol. 132, pp. 1480-1495, ISSN:0006-8950 DOI   Accesso ONLINE all'editore

  Melani A.; Cipriani S.; Corti F.; Eisert W.; Pedata F. (2009). Effects of intravenous administration of dipyridamole in a rat model of chronic cerebral ischemia. EUROPEAN JOURNAL OF NEUROLOGY, vol. 16 (suppl.3), pp. 405-405, ISSN:1351-5101 DOI  

  T.Genovese; A.Melani; E.Esposito; E.Mazzon; R. Di Paola; P.Bramanti; F.Pedata; S.Cuzzocrea (2009). The selective adenosine A2A receptor agonist CGS 21680 reduces JNK MAPK activation in oligodendrocytes in injured spinal cord. SHOCK, vol. 32, pp. 578-585, ISSN:1073-2322 DOI  

  Cipriani S; Bizzoco E; Gianfriddo M; Melani A; Vannucchi M.G; Pedata F (2008). Adenosine A2A receptor antagonism increases nNOS-immunoreactive neurons in the striatum of Huntington transgenic mice. EXPERIMENTAL NEUROLOGY, vol. 213, pp. 163-170, ISSN:0014-4886 DOI  

  Melani A.; Cipriani S.; Bizzoco E.; Gianfriddo M; Vannucchi M.G.; Pedata F. (2008). Adenosine A2A receptor antagonism increases neuronal nitric oxide syntase expression in the striatum of huntington transgenic mice. PURINERGIC SIGNALLING, vol. 4(suppl.1), pp. S42-S43, ISSN:1573-9538 DOI  

  M.L.Trincavelli; A.Melani; S.Guidi; S.Cuboni; S.Cipriani; F.Pedata; C. Martini (2008). Regulation of A(2A) adenosine receptor expression and functioning following permanent focal ischemia in rat brain. JOURNAL OF NEUROCHEMISTRY, vol. 104, pp. 479-490, ISSN:0022-3042 DOI  

  J-F.Chen; P.K.Sonsalla; F.Pedata; A.Melani; M.R.Domenici; P.Popoli; J.Geiger; L.V.Lopes; A.de Mendonça (2007). Adenosine A2A receptors and brain injury: broad spectrum of neuroprotection, multifaceted actions and "fine tuning" modulation.. PROGRESS IN NEUROBIOLOGY, vol. 83, pp. 310-331, ISSN:0301-0082 DOI   Accesso ONLINE all'editore

  PEDATA F; PUGLIESE A.M; COPPI E; POPOLI P; MORELLI M; SCHWARZSCHILD M.A.; MELANI A (2007). Adenosine in the Central Nervous System: Effects on Neurotransmission and Neuroprotection.. CURRENT MEDICINAL CHEMISTRY. IMMUNOLOGY, ENDOCRINE & METABOLIC AGENTS, vol. 4, pp. 304-321, ISSN:1568-0134 DOI  

  J.Borycz; M.F.Pereira; A.Melani; R.J.Rodrigues; A.Köfalvi; L.Panlilio; F.Pedata; S.R.Goldberg; R.A.Cunha; S.Ferré (2007). Differential glutamate-dependent and glutamate-independent adenosine A1 receptor-mediated modulation of dopamine release in different striatal compartments.. JOURNAL OF NEUROCHEMISTRY, vol. 101, pp. 355-363, ISSN:0022-3042 DOI  

  F. PEDATA; A. MELANI; A.M. PUGLIESE ; E. COPPI; S. CIPRIANI; C. TRAINI (2007). The role of ATP and adenosine in the brain under normoxic and ischemic conditions.. PURINERGIC SIGNALLING, vol. 3, pp. 299-310, ISSN:1573-9538 DOI  

  Coppi E; Pugliese AM; Urbani S; Melani A; Cerbai E; Mazzanti B; Bosi A; Saccardi R; Pedata F. (2007). ATP modulates cell proliferation and elicits two different electrophysiological responses in human mesenchymal stem cells.. STEM CELLS, vol. 25, pp. 1840-1849, ISSN:1066-5099 DOI   Accesso ONLINE all'editore

  A. MELANI; M. GIANFRIDDO; M. VANNUCCHI; S. CIPRIANI; P. BARALDI; M.G. GIOVANNINI; F. PEDATA (2006). The selective A(2A) receptor antagonist SCH 58261 protects from neurological deficit, brain damage and activation of p38 MAPK in rat focal cerebral ischemia.. BRAIN RESEARCH, vol. 1073-1074, pp. 470-480, ISSN:0006-8993 DOI  

  Pedata F; Melani A; Gianfriddo M; Vannucchi MG; Cipriani S; Giovannini MG (2006). The selective adenosine A2A antagonist SCH58261 is protective in a model of focal cerebral ischemia in the rat. ACTA PHARMACOLOGICA SINICA, pp. 118-118, ISSN:1671-4083

  A.MELANI; S.AMADIO; M. GIANFRIDDO; M.G.VANNUCCHI; C.VOLONTÈ; G.BERNARDI; F.PEDATA; G.SANCESARIO (2006). P2X(7) receptor modulation on microglial cells and reduction of brain infarct caused by middle cerebral artery occlusion in rat. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, vol. 26, pp. 974-982, ISSN:0271-678X DOI   Accesso ONLINE all'editore

  F. PEDATA; M. GIANFRIDDO; D. TURCHI; A. MELANI (2005). The protective effect of adenosine A2A receptor antagonism in cerebral ischemia. NEUROLOGICAL RESEARCH, vol. 27, pp. 169-174, ISSN:0161-6412

  A. MELANI; D. TURCHI; M. VANNUCCHI; S. CIPRIANI; M. GIANFRIDDO; F. PEDATA (2005). ATP extracellular concentrations are increased in the rat striatum during in vivo ischemia. NEUROCHEMISTRY INTERNATIONAL, vol. 47, pp. 442-448, ISSN:0197-0186

  GIANFRIDDO M.; MELANI A.; TURCHI D.; GIOVANNINI M.G.; F. PEDATA (2004). Adenosine and glutamate extracellular concentrations and mitogen-activated protein kinases in the striatum of Huntington transgenic mice. Selective antagonism of adenosine A2A receptors reduces transmitter outflow.. NEUROBIOLOGY OF DISEASE, vol. 17, pp. 77-88, ISSN:0969-9961 DOI   Accesso ONLINE all'editore

  GIANFRIDDO M.; CORSI C.; MELANI A.; PEZZOLA A.; REGGIO R.; POPOLI P.; F. PEDATA (2003). Adenosine A(2A) antagonism increases striatal glutamate outflow in the quinolinic acid rat model of Huntington's disease.. BRAIN RESEARCH, vol. 979, pp. 225-229, ISSN:0006-8993

  MELANI A; PANTONI L; BORDONI F; GIANFRIDDO M; BIANCHI L; M. VANNUCCHI; BERTORELLI R; MONOPOLI A; PEDATA F. (2003). The selective A2A receptor antagonist SCH 58261 reduces striatal transmitter outflow, turning behavior and ischemic brain damage induced by permanent focal ischemia in the rat. BRAIN RESEARCH, vol. 959, pp. 243-250, ISSN:0006-8993 Accesso ONLINE all'editore

  Melani A; De Micheli E; Pinna G; Alfieri A; Della Corte L; Pedata F. (2003). Adenosine extracellular levels in human brain gliomas: an intraoperative microdialysis study.. NEUROSCIENCE LETTERS, vol. 346, pp. 93-96, ISSN:0304-3940

  F. PEDATA; A.M. PUGLIESE; A. MELANI; M. GIANFRIDDO (2003). A2A receptors in neuroprotection of dopaminergic neurons.. NEUROLOGY, vol. 61, pp. S49-S50, ISSN:0028-3878 Accesso ONLINE all'editore

  CORSI C; PINNA A; GIANFRIDDO M; MELANI A; MORELLI M; F. PEDATA (2003). Adenosine A2A receptor antagonism increases striatal glutamate outflow in dopamine-denervated rats. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 464, pp. 33-38, ISSN:0014-2999

  F. PEDATA; C. CORSI; A. MELANI; F. BORDONI; S. LATINI (2001). Adenosine extracellular brain concentrations and role of A2A receptors in ischemia. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 939, pp. 74-84, ISSN:0077-8923

  Pedata F.; Melani A.; Pantoni L.; Bianchi L.; Bordoni F.; Monopoli A.; Pepeu G. (2001). Effect of A2A receptor antagonism on the histological damage, neurological deficit and striatal adenosine and aminoacid outflow following middle cerebral artery occlusion in the rat. BRITISH JOURNAL OF PHARMACOLOGY, vol. 133 (suppl), pp. 154P-154P, ISSN:1476-5381

  Pedata F.; Melani A.; Pantoni L.; Bianchi L.; Bordoni F.; Monopoli A.; Pepeu G. (2001). Effect of the selective adenosine A2A receptor antagonist, SCH 58261, in a model of permanent focal cerebral ischemia in the rat.. PHARMACOLOGICAL RESEARCH, vol. 43(supplA), pp. 60-60, ISSN:1043-6618

  E. De Micheli; A. Alfieri; G. Pinna; L. Bianchi; M. A. Colivicchi; A. Melani; F. Pedata; L. Della Corte; A. Bricolo (2000). Extracellular levels of taurine in tumoral, peritumoral and normal brain tissue in patients with malignant glioma: An intraoperative microdialysis study. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, vol. 483, pp. 621-625, ISSN:0065-2598

  Pedata F.; Corsi C.; Melani A.; Bianchi L.; Pepeu G. (2000). Effect of A2A receptor antagonism on glutamate outflow from the striatum of young and aged rats in vivo.. DRUG DEVELOPMENT RESEARCH, vol. 50, pp. 71-71, ISSN:1098-2299

  CORSI C.; MELANI A.; BIANCHI L.; F. PEDATA (2000). Striatal A2A adenosine receptor antagonism differentially modifies striatal glutamate outflow in vivo in young and aged rats.. NEUROREPORT, vol. 11, pp. 2591-2595, ISSN:0959-4965

  MELANI A.; PANTONI L.; CORSI C.; BIANCHI L.; MONOPOLI A.; BERTORELLI R.; PEPEU G.; F. PEDATA (1999). Striatal outflow of adenosine, excitatory amino acids, gamma-aminobutyric acid, and taurine in awake and freely moving rats after middle cerebral artery occlusion. Correlations with neurological deficit and histopathological damage.. STROKE, vol. 30, pp. 2448-2455, ISSN:0039-2499

  S. KOPF; A. MELANI; F. PEDATA; G. PEPEU (1999). ADENOSINE AND MEMORY STORAGE: EFFECT OF A(1) AND A(2) RECEPTOR ANTAGONISTS.. PSYCHOPHARMACOLOGY, vol. 146, pp. 214-219, ISSN:0033-3158

  Bianchi L.; Melani A.; Colivicchi A.; De Micheli E.; Alfieri A.; Pinna G.; Pedata F.; Della Corte L. (1999). Intraoperative microdialysis in human brain gliomas: amino acids, adenosine and choline extracellular levels.. PHARMACOLOGICAL RESEARCH, vol. 39 (suppl), pp. 105-105, ISSN:1043-6618

  A. MELANI; C. CORSI; F. PEDATA; L. GIMÉNEZ; E. MARTÍNEZ; S. OGREN; S. FRERRÈ (1999). EFFECT OF N-METHYL-D-ASPARTATE ON MOTOR ACTIVITY AND IN VIVO ADENOSINE STRIATAL OUTFLOW IN THE RAT.. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 385, pp. 15-19, ISSN:0014-2999

  Pinna G.; Pedata F.; Bianchi L.; Alfieri A.; De Micheli E.; Melani A.; Della Corte L.; Colivicchi M.A. (1999). Amino acids, adenosine choline extracellular levels as possible markers in human brain gliomas: an intraoperative microdialysis study.. CLINICAL CHEMISTRY AND LABORATORY MEDICINE, vol. 37, pp. S222-S222, ISSN:1434-6621

  Melani A.; Corsi C.; Pantoni L.; Colivicchi M.A.; Pepeu G.; Pedata F. (1999). Striatal outflow adenosine and amino acid following focal cerebral ischemia: correlation with neurological deficit and histological damage.. PHARMACOLOGICAL RESEARCH, vol. 39 (suppl), pp. 67-67, ISSN:1043-6618

  Corsi C; Melani A; Bianchi L; Pepeu G; Pedata F. (1999). Striatal A2A adenosine receptors differentially regulate spontaneous and K+-evoked glutamate release in vivo in young and aged rats. NEUROREPORT, vol. 10, pp. 687-691, ISSN:0959-4965

  Corsi C.; Melani A.; Colivicchi A.; Pepeu G.; Pedata F. (1999). Excitatory aminoacid and GABA release from the rat striatum in vivo: effect of the selctive A2A adenosine receptor agonist CGS 21680.. PHARMACOLOGICAL RESEARCH, vol. 39 (suppl.), pp. 15-15, ISSN:1043-6618

  CORSI C; MELANI A; BIANCHI L; PEPEU G; F. PEDATA (1999). Effect of adenosine A2A receptor stimulation on GABA release from the striatum of young and aged rats in vivo. NEUROREPORT, vol. 10, pp. 1-5, ISSN:0959-4965

  Melani A.; Pantoni L.; Corsi C.; Colivicchi A.; Bertorelli R. Pepeu G.; Pedata F. (1998). Correlation between adenosine and amino acid outflow and neuropathological outcome in rat striatum following middle cerebral artery occlusion.. DRUG DEVELOPMENT RESEARCH, vol. 43, pp. 56-56, ISSN:1098-2299

  Corsi C.; Melani A.; Colivicchi A.; Pepeu G.; Pedata F. (1998). A2A adenosine receptors inhibits glutamate release in vivo from the striatum of aging rats.. DRUG DEVELOPMENT RESEARCH, vol. 43, pp. 52-52, ISSN:1098-2299

  Pedata F.; Corsi C.; Pazzagli M.; Melani A.; Bianchi L.; Pepeu G. (1997). In vivo amino acid drelease from the striatum of aging rats: adenosine modulation.. PHARMACOLOGICAL RESEARCH, vol. 35, pp. 20-20, ISSN:1043-6618